Pipetting device for tumor early screening detection

By introducing an anti-accidental contact rotating mechanism and a rotating lifting mechanism into the pipetting device, the problems of air entry or liquid outflow in the event of accidental contact in existing devices are solved, achieving higher precision and more stable pipetting operations.

CN121446573APending Publication Date: 2026-02-03XIAMEN SINIAN BIOTECHNOLOGY CO LTD +1
View PDF 1 Cites 0 Cited by

Patent Information

Application Number
CN202411056968.6
Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
Filing Date
2024-08-02
Publication Date
2026-02-03

AI Technical Summary

Technical Problem

Existing pipetting devices for early cancer screening are prone to accidental contact during pipetting, which can lead to air entering or liquid flowing out, affecting pipetting accuracy and stability.

Method used

A pipetting device was designed, which includes an anti-accidental-touch rotating mechanism and a rotating lifting mechanism. The anti-accidental-touch rotating mechanism prevents the threaded rod from rotating due to accidental contact, while the rotating lifting mechanism enables the height and orientation adjustment of the extraction cylinder. Combined with a deceleration mechanism, the stability of the device is improved.

Benefits of technology

It effectively prevents air from entering or liquid from flowing out due to accidental contact during pipetting, improves pipetting accuracy and stability, and facilitates pipetting operations.

✦ Generated by Eureka AI based on patent content.

Smart Images

  • Figure CN121446573A_ABST
    Figure CN121446573A_ABST
Patent Text Reader

Abstract

The invention discloses a pipetting device for tumor early screening detection, and relates to the technical field of medical instruments. The device comprises an extraction cylinder and a rotary lifting mechanism, the bottom of the extraction cylinder penetrates through and is fixedly connected with a liquid suction head, an inner piston of the extraction cylinder is slidably connected with a piston plate, the top of the piston plate is rotatably connected with a threaded rod A, and the top of the threaded rod A is provided with a mistaken touch prevention rotating mechanism; by arranging the mistaken touch prevention rotating mechanism, when a threaded rod A needs to be rotated to drive a piston plate to move, through cooperation of a moving block, an arc-shaped block, a clamping groove and other assemblies, the threaded rod A can be driven to rotate only by pressing a rotating rod downwards and rotating the rotating rod, and after the rotating rod is loosened, a reset spring can drive the rotating rod to move upwards to restore; at the moment, when the rotating rod is rotated again, the threaded rod A cannot be driven to rotate, and the situation that air enters or liquid flows out due to mistaken touch in the liquid transferring process is effectively prevented.
Need to check novelty before this filing date? Find Prior Art

Description

TECHNICAL FIELD

[0001] The application belongs to the technical field of medical appliances, and particularly relates to a pipetting device for early screening detection of tumors. BACKGROUND

[0002] A tumor is a new organism formed by local tissue cell proliferation, and the acidity of the tumor is slightly stronger than that of healthy body tissue. The tumor can form an acid wall to protect itself from the immune system attack. According to the cell characteristics of the new organism and the degree of harm to the body, the tumor is divided into two categories, namely, benign tumor and malignant tumor. The benign tumor grows slowly, and the surface is smooth. The tumor does not invade the adjacent normal tissue. An envelope is often formed around the tumor, so the tumor is obviously separated from the normal tissue. Unless the tumor is located in a vital part, the benign tumor is generally not fatal, and most of the benign tumors can be completely removed and rarely recur. Cancer is the most common malignant tumor. The malignant tumor is divided into cancer and sarcoma. Cancer refers to a malignant tumor originating from epithelial tissue. Sarcoma refers to mesenchymal tissue, including fibrous connective tissue, fat, muscle, blood vessels, bone and cartilage tissue, etc. The malignant tumor occurs, such as the malignant tumor formed by the large intestinal mucosa epithelium, which is called large intestinal mucosa epithelial cancer, and is simply referred to as large intestinal cancer. The skin epithelium forms skin epithelial cancer, which is simply referred to as skin cancer, and so on. Therefore, if a doctor says that someone has cancer, it means that the patient has a malignant tumor. If it is said that someone has stomach cancer, it means that the patient has a cancer formed by the stomach mucosa epithelium. If it is said that the patient has stomach sarcoma, it means that the malignant tumor is not formed by the mucosa epithelial cells, and it may be caused by the smooth muscle cell malignant change or belong to the stomach malignant lymphoma. However, it can be generally said that the patient suffers from cancer. Since the benign tumor and the malignant tumor are different not only in clinical manifestations, but also in prognosis (the final outcome of the patient), once the lump and the above symptoms are found in the body, the patient should go to a doctor in time. Lung cancer is the malignant tumor with the highest incidence and mortality. In the early screening detection of lung cancer, the serum needs to be transferred from a test tube containing serum to another test tube containing reagent, which is commonly referred to as pipetting.

[0003] The utility model discloses a pipette device for early tumor screening detection, which belongs to the technical field of pipette device for early tumor screening detection, and comprises an outer shell, a suction pipe threadedly connected to the bottom side of the outer shell, a top cover installed on the top side of the outer shell, a piston slidingly and sealingly installed in the outer shell, a threaded hole formed in the top side of the top cover, a screw rod threadedly installed in the threaded hole, the bottom end of the screw rod extending into the outer shell and being rotationally connected with the piston, the top end of the screw rod extending out of the threaded hole and being installed with a manual rotating assembly. SUMMARY

[0004] The present application aims to provide a pipette device for early tumor screening detection, which solves the existing problems.

[0005] To solve the above technical problems, the present application is achieved by the following technical solutions:

[0006] The present application is a pipette device for early tumor screening detection, which comprises an extraction cylinder and a rotating lifting mechanism, the bottom of the extraction cylinder is penetrated and fixedly connected with a liquid suction head, the inside of the extraction cylinder is slidingly connected with a piston plate, the top of the piston plate is rotationally connected with a threaded rod A, and the top of the threaded rod A is provided with an anti-mis-touch rotating mechanism; the anti-mis-touch rotating mechanism comprises a rotating rod and a groove body, the bottom of the rotating rod is fixedly connected with a moving block, the surface of the moving block is provided with a groove, the inside of the groove is slidingly connected with a compression spring, the inside of the groove is slidingly connected with an arc-shaped block through the compression spring, the groove body is formed in the inside of the threaded rod A, the inside bottom of the groove body is provided with a return spring, and a clamping groove is formed in the inner wall of the groove body.

[0007] Further, the top of the extraction cylinder is threadedly connected with the threaded rod A through a threaded groove, and rotating the threaded rod A will make the threaded rod A rotate and move upward or downward at the same time.

[0008] Further, the moving block is located in the inside of the groove body, and the end of the return spring away from the inside bottom of the groove body is in initial state and abuts against the bottom of the moving block, and the moving block moves downward to extrude the return spring and make it gradually tighten.

[0009] Further, the arc-shaped block is in abutment with the inner wall of the groove body away from the compression spring in the initial state, and the compression spring is in the initial state of being in the taut state, and the compression spring rebounds to drive the arc-shaped block to move outwardly from the groove.

[0010] Further, the arc surface of the arc-shaped block faces upward, the opening size of the clamping groove is equal to the opening size of the groove, and the arc surface of the arc-shaped block moves into the groove when being extruded, and the arc-shaped block can be clamped into the clamping groove.

[0011] Further, the rotating lifting mechanism comprises a fixed seat and a connecting frame, the inner part of the fixed seat is rotationally connected with a rotating table, the top of the rotating table is rotationally connected with a threaded rod B, the top of the rotating table is fixedly connected with a sliding rod, the connecting frame is slidably connected with the sliding rod, the side surface of the connecting frame is fixedly connected with a fixed frame, the inner side wall of the fixed frame is fixedly connected with the outer surface of the extraction cylinder, and the top of the fixed seat is provided with a speed reduction mechanism.

[0012] Further, the friction force between the rotating table and the fixed seat is greater than the friction force between the threaded rod B and the rotating table, and the rotating table does not rotate when the threaded rod B is rotated.

[0013] Further, the speed reduction mechanism comprises a fixed ring and a connecting block, the bottom of the fixed ring is fixedly connected with the top of the fixed seat, the inner wall of the fixed ring is fixedly connected with a speed reduction block, one end of the connecting block is fixedly connected with the top of the rotating table, the end of the connecting block away from the rotating table is provided with a sliding groove, the sliding groove is provided with a telescopic spring in the inner part, and the inner part of the sliding groove is slidably connected with a contact block through the telescopic spring.

[0014] Further, the end of the contact block away from the telescopic spring is arc-shaped, the material of the speed reduction block is rubber material, resistance is generated when the arc-shaped end of the contact block contacts the rubber material speed reduction block, and the resistance generated when the contact block contacts the speed reduction block is used to slow down the rotating speed of the rotating table.

[0015] The present application has the following beneficial effects:

[0016] 1、The anti-misoperation rotating mechanism is arranged, so that when the threaded rod A needs to be rotated to drive the piston plate to move, the cooperation of the moving block, the arc-shaped block, the clamping groove and other components enables the threaded rod A to be rotated only when the rotating rod is pressed downward, and the reset spring drives the rotating rod to move upward to restore after the rotating rod is released, so that the threaded rod A is not rotated when the rotating rod is rotated again, thereby effectively preventing the air from entering or the liquid from flowing out due to misoperation during the pipetting process.

[0017] 2、The present application is provided with rotating lifting mechanism, thereby achieving the height of the extraction cylinder can be lifted by rotating the threaded rod B after extracting liquid, and the orientation of the extraction cylinder can be changed by pushing the connecting frame to drive the rotating platform to rotate, facilitating the subsequent liquid outlet, making the whole pipetting work more convenient.

[0018] 3、The present application is provided with speed reduction mechanism, thereby achieving the rotation speed of the rotating platform is limited by the cooperation of the connecting block, extrusion block, speed reduction block and other components when the connecting frame drives the rotating platform to rotate, preventing the rotating platform from rotating too fast due to excessive force of the user, causing the extraction cylinder to shake, making the whole device more stable to use.

[0019] Of course, implementing any product of the present application does not necessarily need to achieve all the advantages described above. BRIEF DESCRIPTION OF DRAWINGS

[0020] In order to more clearly illustrate the technical solutions of the embodiments of the present application, the following will briefly introduce the drawings needed to be used in the embodiment description. Obviously, the drawings in the following description are only some embodiments of the present application, and other drawings can also be obtained by those skilled in the art without creative labor.

[0021] Figure 1 It is the three-dimensional front view of the overall structure of the present application.

[0022] Figure 2 It is the three-dimensional back view of the overall structure of the present application.

[0023] Figure 3 It is the three-dimensional sectional view of the overall structure of the present application.

[0024] Figure 4 It is the three-dimensional schematic view of the anti-mis-touch rotating mechanism structure of the present application.

[0025] Figure 5 It is the three-dimensional sectional view of the anti-mis-touch rotating mechanism structure of the present application.

[0026] Figure 6 It is the three-dimensional schematic view of the rotating lifting mechanism structure of the present application.

[0027] Figure 7 It is the three-dimensional sectional view of the rotating lifting mechanism structure of the present application.

[0028] Figure 8 It is the three-dimensional sectional view of the speed reduction mechanism structure of the present application.

[0029] In the drawings, the components represented by each number are listed as follows:

[0030] 1, extraction cylinder; 2, liquid suction head; 3, piston plate; 4, threaded rod A; 5, anti-misoperation rotating mechanism; 51, rotating rod; 52, moving block; 53, groove; 54, compression spring; 55, arc-shaped block; 56, groove body; 57, reset spring; 58, clamping groove; 6, rotating lifting mechanism; 61, fixed seat; 62, rotating table; 63, threaded rod B; 64, sliding rod; 65, connecting frame; 66, fixed frame; 7, speed reduction mechanism; 71, fixed ring; 72, speed reduction block; 73, connecting block; 74, sliding groove; 75, extension spring; 76, contact block. DETAILED DESCRIPTION

[0031] The technical solutions in the embodiments of the present application will be clearly and completely described below with reference to the drawings in the embodiments of the present application. Obviously, the described embodiments are only part of the embodiments of the present application, rather than all the embodiments. Based on the embodiments in the present application, all other embodiments obtained by those skilled in the art without creative work fall within the scope of protection of the present application.

[0032] Please refer to Figures 1-5 The present application is a liquid transfer device for early tumor screening, which comprises an extraction cylinder 1 and a rotating lifting mechanism 6. The bottom of the extraction cylinder 1 is through and fixedly connected with a liquid suction head 2. The inside of the extraction cylinder 1 is slidably connected with a piston plate 3. The top of the piston plate 3 is rotatably connected with a threaded rod A 4. The top of the threaded rod A 4 is provided with an anti-misoperation rotating mechanism 5. The anti-misoperation rotating mechanism 5 comprises a rotating rod 51 and a groove body 56. The bottom of the rotating rod 51 is fixedly connected with a moving block 52. The surface of the moving block 52 is provided with a groove 53. The inside of the groove 53 is slidably connected with a compression spring 54. The inside of the groove 53 is slidably connected with an arc-shaped block 55 through the compression spring 54. The groove body 56 is arranged in the inside of the threaded rod A 4. The inside bottom of the groove body 56 is provided with a reset spring 57. The inner wall of the groove body 56 is provided with a clamping groove 58.

[0033] The top of the extraction cylinder 1 is threadedly connected with the threaded rod A 4 through a threaded groove. When the threaded rod A 4 is rotated, the threaded rod A 4 is rotated and moved upward or downward at the same time.

[0034] The moving block 52 is located in the inside of the groove body 56. The end of the reset spring 57 away from the inside bottom of the groove body 56 is in contact with the bottom of the moving block 52 in the initial state. When the moving block 52 moves downward, the reset spring 57 is compressed and gradually tightened.

[0035] The end of the arc-shaped block 55 away from the compression spring 54 is in contact with the inner wall of the groove body 56 in the initial state. The compression spring 54 is in the tightened state in the initial state. When the compression spring 54 rebounds, the arc-shaped block 55 is moved outward from the groove 53.

[0036] The arc surface of the arc-shaped block 55 faces upward, the opening size of the clamping groove 58 is equal to the opening size of the groove 53, the arc surface of the arc-shaped block 55 is moved into the groove 53 when being extruded, and the arc-shaped block 55 can be clamped into the clamping groove 58.

[0037] The rotating lifting mechanism 6 comprises a fixed seat 61 and a connecting frame 65, the inner part of the fixed seat 61 is rotationally connected with a rotating table 62, the top of the rotating table 62 is rotationally connected with a threaded rod B63, the top of the rotating table 62 is fixedly connected with a sliding rod 64, the connecting frame 65 is slidingly connected with the sliding rod 64, the side of the connecting frame 65 is fixedly connected with a fixed frame 66, the inner side wall of the fixed frame 66 is fixedly connected with the outer surface of the extraction cylinder 1, and the top of the fixed seat 61 is provided with a speed reduction mechanism 7.

[0038] The friction force between the rotating table 62 and the fixed seat 61 is greater than the friction force between the threaded rod B63 and the rotating table 62, and the rotating table 62 will not rotate when the threaded rod B63 is rotated.

[0039] The speed reduction mechanism 7 comprises a fixed ring 71 and a connecting block 73, the bottom of the fixed ring 71 is fixedly connected with the top of the fixed seat 61, the inner wall of the fixed ring 71 is fixedly connected with a speed reduction block 72, one end of the connecting block 73 is fixedly connected with the top of the rotating table 62, the end of the connecting block 73 away from the rotating table 62 is provided with a sliding groove 74, the inner part of the sliding groove 74 is provided with a telescopic spring 75, and the inner part of the sliding groove 74 is slidingly connected with a contact block 76 through the telescopic spring 75.

[0040] The end of the contact block 76 away from the telescopic spring 75 is arc-shaped, the material of the speed reduction block 72 is rubber material, and resistance is generated when the arc-shaped end of the contact block 76 is in contact with the rubber material speed reduction block 72.

[0041] One specific application of the embodiment is: when pipetting is needed, the liquid suction head 2 at the bottom of the extraction cylinder 1 is inserted into the liquid to be extracted, the position of the swing lever 51 is adjusted, the position of the handle on the swing lever 51 is directed to the front side, the swing lever 51 is pressed downward, the swing lever 51 moves downward to drive the moving block 52 to move downward, the moving block 52 moves downward to drive the groove 53 to fit with the clamping groove 58, at this time the reset spring 57 will rebound to drive the arc block 55 to clamp into the clamping groove 58, at this time rotating the swing lever 51 will drive the threaded rod A4 to rotate through the cooperation of the arc block 55 and the clamping groove 58, the rotation of the threaded rod A4 will cooperate with the threaded groove at the top of the extraction cylinder 1 to make the threaded rod A4 move upward while rotating, the upward movement of the threaded rod A4 will drive the piston plate 3 to move upward, the upward movement of the piston plate 3 will cause the bottom of the extraction cylinder 1 to generate negative pressure, so that the liquid is sucked into the extraction cylinder 1 through the liquid suction head 2, the whole process is more accurate than manual liquid extraction, and when the swing lever 51 is released, the reset spring 57 will rebound to drive the moving block 52 to move upward, the moving block 52 will move upward to drive the arc block 55 to move upward, at this time the arc surface of the arc block 55 will be extruded with the inner wall of the clamping groove 58, at this time the arc block 55 will shrink into the groove 53 and will not affect the upward movement of the moving block 52, after the arc block 55 leaves the clamping groove 58, rotating the swing lever 51 will not drive the threaded rod A4 to rotate, effectively preventing the threaded rod A4 from rotating due to accidental touch during subsequent pipetting, causing the piston plate 3 to move, thereby effectively preventing air from entering or liquid from flowing out during pipetting due to accidental touch.

[0042] After the liquid extraction is completed, the threaded rod B63 can be rotated, the rotation of the threaded rod B63 will drive the connecting frame 65 to move upward or downward along the slide rod 64 through the cooperation between the threads, thereby adjusting the height of the extraction cylinder 1, and driving the turntable 62 to rotate by pushing the connecting frame 65 can change the position of the extraction cylinder 1, the height of the extraction cylinder 1 is adjusted by rotating the threaded rod B63, and the orientation of the extraction cylinder 1 is changed by driving the turntable 62 to rotate by pushing the connecting frame 65, which facilitates subsequent liquid discharge, making the whole pipetting work more convenient and facilitating subsequent pipetting operation.

[0043] When the fixed frame 66 is pushed to drive the rotating table 62 to rotate, the connecting block 73 rotates with the rotating table 62, the connecting block 73 drives the contact block 76 to rotate, the contact block 76 rotates to contact the deceleration block 72 on the inner wall of the fixed ring 71, the arc-shaped end of the contact block 76 contacts the rubber deceleration block 72 to generate resistance, the contact block 76 is also extruded to move a small distance into the sliding groove 74, so that the rotating table 62 cannot rotate, the resistance generated when the contact block 76 contacts the deceleration block 72 slows down the rotating speed of the rotating table 62, prevents the user from pushing the fixed frame 66 too hard to make the rotating table 62 rotate too fast, and the liquid in the extraction cylinder 1 is easy to shake and leak, effectively makes the whole device more stable to use.

[0044] In the description of the present specification, the description referring to the terms "one embodiment", "an example", "a specific example" and the like means that the specific features, structures, materials or characteristics described in connection with the embodiment or example are included in at least one embodiment or example of the present application. In the present specification, the illustrative description of the above terms does not necessarily refer to the same embodiment or example. Moreover, the specific features, structures, materials or characteristics described can be combined in any one or more embodiments or examples in a suitable manner.

[0045] The preferred embodiments of the application disclosed above are only used to help explain the application. The preferred embodiments do not describe all the details, nor limit the application to the specific embodiments described. Obviously, according to the content of the present specification, many modifications and changes can be made. The present specification selects and specifically describes these embodiments in order to better explain the principles and practical applications of the application, so that those skilled in the art can well understand and utilize the application. The application is limited only by the claims and their full scope and equivalents.

Claims

1. A pipetting device for early tumor screening, comprising an extraction tube (1) and a rotating lifting mechanism (6), characterized in that: The bottom of the extraction cylinder (1) is connected to a liquid suction head (2), the piston inside the extraction cylinder (1) is slidably connected to a piston plate (3), the top of the piston plate (3) is rotatably connected to a threaded rod A (4), and the top of the threaded rod A (4) is provided with an anti-accidental contact rotation mechanism (5). The anti-accidental touch rotation mechanism (5) includes a rotating rod (51) and a groove (56). A moving block (52) is fixedly connected to the bottom of the rotating rod (51). A groove (53) is provided on the surface of the moving block (52). A compression spring (54) is slidably connected inside the groove (53). An arc-shaped block (55) is slidably connected inside the groove (53) through the compression spring (54). The groove (56) is opened inside the threaded rod A (4). A reset spring (57) is provided at the bottom of the groove (56). A slot (58) is provided on the inner wall of the groove (56).

2. The pipetting device for early tumor screening according to claim 1, characterized in that, The top of the extraction cylinder (1) is threadedly connected to the threaded rod A (4) by a threaded groove.

3. The pipetting device for early tumor screening according to claim 2, characterized in that, The movable block (52) is located inside the groove (56), and the end of the return spring (57) away from the bottom of the groove (56) is initially in contact with the bottom of the movable block (52).

4. The pipetting device for early tumor screening according to claim 3, characterized in that, The end of the arc-shaped block (55) away from the compression spring (54) initially abuts against the inner wall of the groove (56), and the compression spring (54) is initially in a taut state.

5. A pipetting device for early tumor screening according to claim 4, characterized in that, The arc surface of the arc block (55) faces upward, and the opening size of the slot (58) is equal to the opening size of the groove (53).

6. A pipetting device for early tumor screening according to claim 5, characterized in that, The rotating lifting mechanism (6) includes a fixed base (61) and a connecting frame (65). A turntable (62) is rotatably connected inside the fixed base (61). A threaded rod B (63) is rotatably connected to the top of the turntable (62). A sliding rod (64) is fixedly connected to the top of the turntable (62). The connecting frame (65) is slidably connected to the sliding rod (64). A fixed frame (66) is fixedly connected to the side of the connecting frame (65). The inner side wall of the fixed frame (66) is fixedly connected to the outer surface of the extraction cylinder (1). A slowing mechanism (7) is provided on the top of the fixed base (61).

7. A pipetting device for early tumor screening according to claim 6, characterized in that, The frictional force between the turntable (62) and the fixed seat (61) is greater than the frictional force between the threaded rod B (63) and the turntable (62).

8. A pipetting device for early tumor screening according to claim 7, characterized in that, The deceleration mechanism (7) includes a fixed ring (71) and a connecting block (73). The bottom of the fixed ring (71) is fixedly connected to the top of the fixed base (61). A deceleration block (72) is fixedly connected to the inner wall of the fixed ring (71). One end of the connecting block (73) is fixedly connected to the top of the turntable (62). A sliding groove (74) is provided at the end of the connecting block (73) away from the turntable (62). A telescopic spring (75) is provided inside the sliding groove (74). A contact block (76) is slidably connected inside the sliding groove (74) through the telescopic spring (75).

9. A pipetting device for early tumor screening according to claim 8, characterized in that, The end of the contact block (76) away from the telescopic spring (75) is arc-shaped, and the deceleration block (72) is made of rubber.

Citation Information

Patent Citations

  • Pipetting device for tumor early screening detection

    CN210545206U