Candida vesii and application thereof

CN121450448APending Publication Date: 2026-02-03CATHAY BIOTECH INC +1
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Patent Information

Application Number
CN202411020865.4
Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
Filing Date
2024-07-29
Publication Date
2026-02-03

AI Technical Summary

Technical Problem

Traditional chemical synthesis methods for ω-hydroxy fatty acids are complex and difficult to separate, while microbial fermentation methods have not yet been industrialized. Therefore, there is a need to develop efficient methods for producing ω-hydroxy fatty acids.

Method used

By genetically modifying the fatty alcohol dehydrogenase activity of Candida strains, Candida viscera CATH2303 was obtained. Strains with ω-hydroxy fatty acid production capacity were obtained through mutagenesis screening, and fatty acids or their derivatives were used as substrates for fermentation production.

Benefits of technology

It significantly increases the yield of ω-hydroxy fatty acids, has the potential for industrial-scale production, and utilizes renewable resources to replace petroleum alkanes, which meets the requirements of sustainable development.

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Abstract

The invention provides a Candida viscera CATH2303 (Candida viscera CATH2303) and an application of the Candida viscera CATH2303. The Candida viscera CATH2303 The candida vesii provided by the invention has reduced fatty alcohol dehydrogenase activity or does not have fatty alcohol dehydrogenase activity, and can efficiently utilize fatty acid or derivatives thereof as a substrate to produce omega-hydroxy fatty acid, and the yield is obviously improved. The candida vesii and the method for producing the omega-hydroxy fatty acid by using the candida vesii, provided by the invention, have the potential of industrial large-scale production.
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Citation Information

Patent Citations

  • Candida viswanathii and application thereof

    CN111748480A

  • Genetically engineered bacterium for producing binary acid and application of genetically engineered bacterium

    CN116218696A