Protein powder with dual health functions of increasing muscle and bone density as well as preparation method and application of protein powder

This scientifically formulated protein powder combines whey protein, soy protein isolate, calcium β-hydroxy-β-methylbutyrate, and calcium salts to address the shortcomings of existing protein powders in muscle and bone health, achieving dual health benefits for both muscles and bones. It is suitable for sports nutrition, health care for middle-aged and elderly people, and postoperative rehabilitation.

CN121512191APending Publication Date: 2026-02-13HARBIN PHARM GROUP SANJING PHARMACEUTICAL CO LTD
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Patent Information

Application Number
CN202511737730.4
Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
Filing Date
2025-11-25
Publication Date
2026-02-13

AI Technical Summary

Technical Problem

Existing protein powder products cannot simultaneously meet the needs of muscle growth and bone health, and have problems such as poor taste and insufficient mixing uniformity, which limits their application, especially among athletes and the middle-aged and elderly.

Method used

Using a scientific formula, this protein powder combines whey protein, soy protein isolate, calcium β-hydroxy-β-methylbutyrate (CaHMB) and calcium salts, along with resistant dextrin, suspending agents and sweeteners, to create an easy-to-mix and palatable protein powder that meets the dual needs of muscle and bone health.

Benefits of technology

It simultaneously improves muscle and bone health, enhances athletic performance and physical function in middle-aged and elderly people, and solves the shortcomings of traditional protein powder in terms of taste and mixing uniformity. It is suitable for fitness and muscle building, health care for middle-aged and elderly people, and postoperative rehabilitation.

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Abstract

The invention relates to protein powder with dual health functions of increasing muscle and bone density as well as a preparation method and application of the protein powder. Through a scientific formula, the protein powder is functional protein powder combining calcium and calcium beta-hydroxy-beta-methylbutyrate (CaHMB), and is especially suitable for the fields of sports nutrition, middle-aged and elderly health care and postoperative rehabilitation. The core components comprise high-content high-quality animal and plant double proteins, CaHMB and calcium, and have the innovative advantages of being scientific in formula, high in content, easy to brew, good in taste and wide in application range. The protein powder disclosed by the invention can effectively improve muscle growth efficiency, prevent exercise-induced bone calcium loss, resist age-related muscle loss and osteoporosis and maintain action ability, and is especially suitable for fitness and muscle building people, middle-aged and elderly people and postoperative rehabilitation or malnutrition people.
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Description

Technical Field

[0001] This invention relates to the field of muscle-building and bone health products, specifically to a protein powder with dual health functions of increasing muscle and bone density, its preparation method, and its application, applicable to sports nutrition, health care for middle-aged and elderly people, and postoperative rehabilitation. Background Technology

[0002] With increasing health awareness, protein supplements are being used more and more widely among athletes, the elderly, and rehabilitation patients. However, existing protein powder products have limited functionality and cannot simultaneously meet the needs of muscle growth and bone health. For example, athletes often face bone calcium loss during muscle building, while the elderly need to combat both muscle loss and osteoporosis. In addition, existing protein powders have shortcomings in terms of taste, mixing uniformity, and reconstitution properties. For example, calcium β-hydroxy-β-methylbutyrate (CaHMB) has a bitter taste, and the mineral ingredients have a gritty texture, which limits the widespread application of these products.

[0003] Protein powder: Protein not only promotes tissue growth and repair but also provides ample energy. Whey protein and soy protein are excellent choices for sports nutrition. They contain branched-chain amino acids and functional peptides, which can relieve muscle soreness, repair sports injuries, and improve muscle mass. Compared to casein, whey protein is more effective for skeletal muscle synthesis, helps with weight management, prevents immune imbalance caused by over-exercise, enriches serum globulins, and regulates immune stress. Appropriate supplementation with this type of nutrient during exercise can enhance athletic performance and the body's repair capabilities, leading to better athletic performance. Meanwhile, protein is also crucial for maintaining bodily functions in middle-aged and elderly individuals. Whey protein and soy protein are easily absorbed and are ideal nutritional supplement choices. They contain high-quality amino acids and immunoglobulins, which can slow muscle loss, repair body tissues, improve the physical condition of middle-aged and elderly individuals, enhance immunity, reduce the risk of infection, and help maintain a healthy weight, alleviating discomfort caused by physical decline. Appropriate daily supplementation can help middle-aged and elderly individuals maintain vitality and improve their quality of life.

[0004] Calcium β-hydroxy-β-methylbutyrate: Maintaining muscle mass and strength is crucial for ensuring systemic protein metabolism, wound healing, organ function, skin integrity, and immune function, while also enhancing physical reserves. Studies show that β-hydroxy-β-methylbutyrate (HMB) promotes muscle protein synthesis and slows muscle protein breakdown by both upregulating protein synthesis signaling pathways and downregulating protein breakdown signaling pathways. Research has measured fasting plasma HMB concentrations in people of different ages, showing that plasma HMB concentrations decrease with age, with children having the highest average HMB concentration, followed by young adults and the elderly. Furthermore, plasma HMB concentrations in adults show a significant positive correlation with muscle mass and strength. Calcium β-hydroxy-β-methylbutyrate (CaHMB), a new resource food ingredient, is one of the common supplemental forms of HMB and is widely used in food. Its applications include animal nutrition, sports nutrition, and special medical purpose formula foods. The application of CaHMB is mainly based on its ability to promote muscle synthesis and reduce muscle protein degradation. In sports nutrition, CaHMB can promote muscle volume increase, increase muscle strength, and improve muscle repair after exercise.

[0005] Calcium: Calcium is an essential macroelement for the human body, its core function being to build strong bones and teeth, and maintaining key physiological functions such as nerve conduction, muscle contraction, and blood clotting. Organic calcium is a superior supplementation choice, as it is gentle on the stomach and does not rely on stomach acid. Its absorption rate is much higher than inorganic calcium, and it does not cause discomfort such as bloating or constipation, making it suitable for long-term supplementation by all types of people. For athletes, calcium can increase bone density, strengthen bone resilience, aid muscle contraction and energy metabolism, reduce the risk of bone injury and muscle cramps during exercise, improve muscle endurance, prevent decreased athletic performance due to calcium deficiency, maintain normal neuromuscular excitability, and make athletic performance more stable. For middle-aged and elderly people, calcium can slow bone loss, prevent osteoporosis, reduce the risk of fractures, maintain cardiovascular stability, and relieve discomfort such as limb numbness and muscle soreness. Appropriate daily supplementation can help athletes improve athletic performance and reduce the probability of injury, and also help middle-aged and elderly people consolidate bone health, maintain physical activity, and improve quality of life.

[0006] Patent CN107440126A discloses a protein powder for relieving exercise fatigue, but it mainly focuses on anti-fatigue and muscle building, without addressing bone health protection. While patent CN108651998A adds multiple functional ingredients, its formula is complex and the taste issue remains unresolved. Therefore, there is an urgent need to develop a protein powder with a scientifically formulated and optimized process to fill the market gap for the combined needs of "muscle + bone."

[0007] Currently, the market supply of nutritional supplements specifically for sarcopenia is insufficient. Existing nutritional compositions designed to improve muscle function and endurance generally contain fats, casein, and organic acid salts containing trace elements such as potassium, sodium, and phosphorus. These components play multiple roles in the products. However, for older adults with declining digestive and metabolic functions, especially those with sarcopenia, the presence of these components poses significant health risks. Given these issues, there is an urgent market need for a functional food product specifically designed for older adults with sarcopenia. This product should possess the following characteristics: ① Reduce gastrointestinal burden: Avoid ingredients that may increase digestive and metabolic burden, such as high-sodium, high-phosphorus organic acid salts, casein, and fat. ② Maintain muscle health: Provide easily absorbed protein and other nutrients through a scientifically formulated approach to support muscle synthesis and repair. ③ Prevent and improve sarcopenia: Help older adults maintain muscle function and endurance through a balanced combination of nutrients, slowing down the progression of muscle loss. In conclusion, developing a nutritional supplement suitable for older adults with sarcopenia is not only of significant health importance but also meets market demand. Summary of the Invention

[0008] To address the shortcomings of existing technologies, the purpose of this invention is to provide a protein powder with dual health functions of increasing muscle and bone density, as well as its preparation method and applications. This protein powder, through scientific formulation, is a functional protein powder that combines calcium and calcium β-hydroxy-β-methylbutyrate (CaHMB), and is particularly suitable for sports nutrition, health care for middle-aged and elderly people, and postoperative rehabilitation.

[0009] To achieve the above objectives, the first aspect of the present invention provides a protein powder with dual health functions of increasing muscle and bone density, comprising the following components by weight: 30-40 parts whey protein, 25-35 parts soy protein isolate, 1-10 parts calcium β-hydroxy-β-methylbutyrate (CaHMB), 1-10 parts calcium salt, 8-20 parts resistant dextrin, 0.5-1.5 parts suspending agent, 0.1-1 part sweetener, and 0.3-3 parts edible flavoring.

[0010] In this invention, both whey protein and soy protein isolate are high-quality proteins, whose core functions are to supplement the amino acids needed by the human body, aid in muscle synthesis and repair, and maintain bodily functions. The advantages of whey protein are: rapid absorption, quick energy supply, an amino acid ratio close to human needs, and high utilization rate. The advantages of soy protein isolate are: it contains dietary fiber and plant-based active ingredients, which are beneficial to cardiovascular health.

[0011] Calcium β-hydroxy-β-methylbutyrate reduces post-exercise muscle damage and aids in repair and growth by inhibiting muscle protein breakdown and promoting muscle protein synthesis. It enhances athletic performance and endurance, delays fatigue, and helps maintain muscle mass, making it particularly suitable for fitness enthusiasts and the elderly. It is a high-quality nutritional supplement that balances muscle protection and performance support. When combined with protein powder, calcium β-hydroxy-β-methylbutyrate creates a synergistic effect of "synthesis + protection."

[0012] Calcium plays a vital role in bone and teeth mineralization, maintaining nerve conduction and muscle contraction, and regulating blood clotting. It strengthens bones and teeth, prevents osteoporosis, and ensures normal heartbeat and neuromuscular function, making it crucial for bone health and overall bodily function at all ages. The combination of calcium and protein powder provides the dual health benefits of increased muscle and bone density.

[0013] Resistant dextrin, as a water-soluble dietary fiber, can regulate gut microbiota, promote intestinal motility, control blood sugar and lipids, and increase satiety to aid in weight management. In powder form, it can improve solubility, enhance the taste of instant preparation, and prevent clumping. As a low-calorie filler, it does not affect the absorption of core nutrients, combining nutritional benefits with processing suitability.

[0014] The core function of suspending agents is to prevent the active ingredients from settling and clumping, improve dispersion uniformity, allow powders to dissolve quickly and prevent separation when mixed with water, while also optimizing the smoothness of the taste and ensuring consistent intake of ingredients each time. The application of resistant dextrin and suspending agents solves problems such as the gritty texture of mineral raw materials.

[0015] Sweeteners in powders improve taste, mask off-flavors of raw materials, and are low in calories, so they don't affect blood sugar. Flavorings give powders a pleasant taste and solve the bitterness problem of calcium β-hydroxy-β-methylbutyrate (CaHMB). The combination of these two enhances the eating experience, making the product more acceptable and ensuring consumer compliance.

[0016] The calcium salt includes one of calcium carbonate, calcium citrate, calcium citrate malate, and milk mineral salts.

[0017] The calcium salt has a particle size of 1000-2000 mesh.

[0018] The whey protein includes whey protein concentrate and whey protein isolate, with a protein content greater than 80%.

[0019] The suspending agent includes one of xanthan gum, guar gum, carrageenan, pectin, and maltodextrin.

[0020] The sweetener includes one of steviol glycosides, mogrosides, sucralose, aspartame, and neotame.

[0021] Preferably, a protein powder with dual health functions of increasing muscle and bone density comprises, by weight, the following components: 35-40 parts whey protein, 30-35 parts soy protein isolate, 5-8 parts calcium β-hydroxy-β-methylbutyrate (CaHMB), 4-8 parts milk mineral salt, 10-15 parts resistant dextrin, 1.0-1.2 parts xanthan gum, 0.2-0.5 parts mogroside, and 1-2 parts edible flavor.

[0022] A second aspect of the present invention also provides a method for preparing the protein powder, comprising the following steps.

[0023] Weighing: Accurately weigh each material according to the formula ratio.

[0024] Mixing 1: Add equal amounts of sweetener and resistant dextrin to the mixture twice, mix thoroughly, and obtain Mixture 1.

[0025] Mixing 2: Add calcium salt and an equal amount of soy protein isolate into a hopper mixer, mix, and sieve to obtain mixture 2.

[0026] Mixing 3: Add mixture 1, mixture 2, calcium β-hydroxy-β-methylbutyrate, edible flavoring, suspending agent, remaining resistant dextrin, and remaining soy protein isolate into a hopper mixer and mix to obtain mixture 3.

[0027] Mixing 4: Add the mixture 3 and whey protein into the hopper mixer and mix.

[0028] Preferably, the mixing time is 20-30 minutes.

[0029] Packaging: The material is divided into composite film bags using a multi-row back-sealing automatic powder packaging machine, and then the outer packaging is carried out after the dispensing is completed.

[0030] The protein powder of the present invention has the following innovative advantages.

[0031] Scientifically formulated: Combining calcium and calcium β-hydroxy-β-methylbutyrate (CaHMB), it can simultaneously meet the needs of muscle and bone health.

[0032] High content and reasonable ratio: High in protein and calcium, rich in nutrients.

[0033] Easy to prepare and tastes good: It solves the problems of traditional protein powder being difficult to prepare and having a gritty texture, resulting in a better taste.

[0034] Wide range of applications: Especially suitable for fitness enthusiasts, middle-aged and elderly people, as well as those recovering from surgery or suffering from malnutrition. Detailed Implementation

[0035] The present invention will be further described below with reference to the embodiments, but the scope of protection of the present invention is not limited thereto.

[0036] Example 1 A protein powder with dual health benefits of increasing muscle and bone density and its preparation method, comprising the following components by weight: 35 parts concentrated whey protein, 30 parts soy protein isolate, 5 parts calcium β-hydroxy-β-methylbutyrate (CaHMB), 7.5 parts calcium citrate, 19.2 parts resistant dextrin, 1 part xanthan gum, 0.3 parts mogroside, and 2 parts edible flavoring.

[0037] The preparation method is as follows: 1. Weighing: Accurately weigh each material according to the formula ratio; 2. Mixing 1: Mix mogrosides with an equal amount of resistant dextrin in two separate steps, mixing thoroughly to obtain mixture 1; 3. Mixing 2: Add calcium citrate and an equal amount of soy protein isolate into a hopper mixer, mix for 10 minutes, and sieve to obtain mixture 2; 4. Mixing 3: Add mixture 1, mixture 2, calcium β-hydroxy-β-methylbutyrate, edible flavoring, xanthan gum, the remaining resistant dextrin, and the remaining soy protein isolate into a hopper mixer and mix for 10 minutes to obtain mixture 3; 5. Mixing 4: Add the mixture from step 3 and the concentrated whey protein to the hopper mixer and mix for 20 minutes; 6. Packaging: Use a multi-row back-sealing automatic powder packaging machine to divide the material into composite film bags, and then perform outer packaging after the dispensing is completed.

[0038] Example 2 A protein powder with dual health benefits of increasing muscle and bone density, and its preparation method, comprises the following components by weight: 38 parts concentrated whey protein, 28 parts soy protein isolate, 8 parts calcium β-hydroxy-β-methylbutyrate (CaHMB), 8 parts milk mineral salt, 14 parts resistant dextrin, 1.4 parts pectin, 0.1 parts steviol glycosides, and 2.5 parts edible flavoring. The preparation method is the same as in Example 1.

[0039] Example 3 A protein powder with dual health benefits of increasing muscle and bone density and its preparation method are disclosed. By weight, the powder comprises the following components: 33 parts whey protein isolate, 35 parts soy protein isolate, 3 parts calcium β-hydroxy-β-methylbutyrate (CaHMB), 6 parts calcium carbonate, 20 parts resistant dextrin, 0.9 parts carrageenan, 0.1 parts sucralose, and 2 parts flavoring. The preparation method is the same as in Example 1.

[0040] Comparative Example Calcium β-hydroxy-β-methylbutyrate (CaHMB) and calcium salt were removed from the formulation, and resistant dextrin was used as an excipient to replace the two removed raw materials. The finished product was prepared according to the preparation process in Example 1.

[0041] Use it to verify the effect.

[0042] Bone density enhancement test: Fifty middle-aged and elderly individuals (aged ≥ 65 years) voluntarily participated in the trial. Ultrasonic bone densitometer testing confirmed that the subjects' bone density was below the normal standard for their age group (i.e., osteoporosis or osteopenia), and they had not received any drug treatment or had other organic lesions. The 50 subjects were randomly divided into 5 groups of 10 each. The example and comparative groups consumed the corresponding composition daily at the prescribed dosage, while the control group consumed a placebo, maltodextrin, once daily at a dose of 10g for 6 months.

[0043] Heel bone mineral density was measured in subjects using an ultrasonic bone densitometer before consumption (0 months) and after the trial (6 months). The results are as follows.

[0044] Based on the data above, it can be seen that the compositions of Examples 1-3 significantly increased the bone mineral density of the subjects after 6 months, compared with the control group and the comparative example, indicating that they have a significant bone formation promoting effect.

[0045] Muscle strength test: Fifty middle-aged and elderly individuals (aged ≥ 65 years) voluntarily participated in the trial. Dual-energy X-ray absorptiometry (DXA) confirmed that the subjects had reduced muscle mass without any drug treatment or other organic lesions. The 50 subjects were randomly divided into 5 groups of 10 each. The example and comparative groups consumed the corresponding composition daily at the prescribed dosage, while the control group consumed a placebo maltodextrin, 10g once daily for 3 months.

[0046] Grip strength was measured in subjects using a grip strength meter before consumption (0 months) and after the trial (3 months).

[0047] The results are as follows:

[0048] The data above shows that, compared with the control group, the compositions of Examples 1-3 significantly improved grip strength after 3 months of consumption, indicating a muscle-building effect. The control group also showed a certain increase in grip strength compared to the control group. However, the muscle-building effect of the compositions of Examples 1-3 was more pronounced.

[0049] in conclusion: The protein powder of this invention, through a scientific formula, combines calcium and calcium β-hydroxy-β-methylbutyrate (CaHMB) to simultaneously meet the health needs of muscles and bones. It boasts unique advantages such as high content, a reasonable ratio, ease of preparation, and good taste, making it particularly suitable for fitness enthusiasts aiming to build muscle, middle-aged and elderly individuals, and those recovering from surgery or suffering from malnutrition. Through efficacy verification, the protein powder of this invention has proven to be safe and reliable, exhibiting significant muscle and bone health-promoting effects.

Claims

1. A protein powder with dual health functions of increasing muscle and bone density, its preparation method, and its application, characterized in that, By weight, it includes the following components: 30-40 parts whey protein, 25-35 parts soy protein isolate, 1-10 parts calcium β-hydroxy-β-methylbutyrate (CaHMB), 1-10 parts calcium salt, 8-20 parts resistant dextrin, 0.5-1.5 parts suspending agent, 0.1-1 part sweetener, and 0.3-3 parts edible flavoring.

2. The protein powder according to claim 1, characterized in that, The calcium salt includes one of calcium carbonate, calcium citrate, calcium citrate malate, and milk mineral salts.

3. The protein powder according to claim 1, characterized in that, The calcium salt has a particle size of 1500-2000 mesh.

4. The protein powder according to claim 1, characterized in that, The whey protein includes whey protein concentrate and whey protein isolate, with a protein content greater than 80%.

5. The protein powder according to claim 1, characterized in that, The suspending agent includes one of xanthan gum, guar gum, carrageenan, pectin, and maltodextrin.

6. The protein powder according to claim 1, characterized in that, The sweetener includes one of steviol glycosides, mogrosides, sucralose, aspartame, and neotame.

7. A method for preparing the protein powder according to any one of claims 1-6, characterized in that, Its preparation method includes the following steps: (1) Weighing: Accurately weigh each material according to the formula ratio; (2) Mixing 1: The sweetener is mixed with an equal amount of resistant dextrin in two separate steps, and the mixture is mixed evenly to obtain mixture 1; (3) Mixing 2: Add calcium salt and an equal amount of soy protein isolate into a hopper mixer, mix, and sieve to obtain mixture 2; (4) Mixing 3: Mixing material 1, mixing material 2, calcium β-hydroxy-β-methylbutyrate, edible flavoring, suspending agent, remaining resistant dextrin, and remaining soy protein isolate are put into the hopper mixer and mixed to obtain mixing material 3; (5) Mixing 4: Add the mixture 3 and whey protein into the hopper mixer and mix; (6) Packaging: Use a multi-row back-sealing automatic powder packaging machine to divide the material into composite film bags, and then carry out outer packaging after the division is completed.

8. The preparation method according to claim 7, characterized in that, All mixing steps are completed in a hopper mixer, with a mixing time of 10-30 minutes.

9. The protein powder according to any one of claims 1-6 may be used in sports nutrition, health care for the middle-aged and elderly, or postoperative rehabilitation.

Citation Information

Patent Citations

  • Albumen powder capable of relieving exercise fatigue and preparation method thereof

    CN107440126A

  • Whey protein powder having function of relieving weariness and preparation method of whey protein powder

    CN108651998A