Dual-emissive molecularly imprinted ratiometric fluorescent sensor, preparation method thereof and application thereof in detection of chlortetracycline
By combining ratiometric fluorescence and molecular imprinting techniques, a dual-emission molecular imprinted ratiometric fluorescence sensor was prepared, solving the problem of detecting complex matrices of chlortetracycline in existing technologies. This sensor achieves rapid, sensitive, and visualized detection, making it suitable for practical applications.
CN121555192BActive Publication Date: 2026-06-02BINZHOU MEDICAL COLLEGE
Patent Information
- Authority / Receiving Office
- CN · China
- Patent Type
- Patents(China)
- Current Assignee / Owner
- BINZHOU MEDICAL COLLEGE
- Filing Date
- 2026-01-22
- Publication Date
- 2026-06-02
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Figure CN121555192B_ABST
Abstract
This invention discloses a dual-emission molecularly imprinted ratiometric fluorescence sensor, its preparation method, and its application in the detection of chlortetracycline, belonging to the field of chemical sensor technology. The preparation method of this sensor includes the following steps: preparing silica-quantum dot composite nanoparticles; preparing a molecularly imprinted polymer using salicylamide as a template molecule; and using a post-mixing strategy to mix the molecularly imprinted polymer and silica-quantum dot composite nanoparticles in HEPES buffer to construct the dual-emission molecularly imprinted ratiometric fluorescence sensor. The advantages of this invention are: the dual-emission molecularly imprinted ratiometric fluorescence sensor provided by this invention exhibits rich fluorescence color changes, enabling rapid, highly sensitive, and visual detection of chlortetracycline; and the entire detection process is simple, convenient, and fast, making it suitable for widespread application in practical applications.
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