Animal cervix uteri slow-release drug delivery device

Abstract

The invention relates to an animal cervix uteri slow-release drug delivery device which comprises a drug bin and a supporting part, the drug bin is of a columnar structure, the supporting part is arranged on the rear portion of the drug bin, the supporting part is of a support type structure on the whole, a traction part is further arranged on the supporting part, and the traction part drags folding of the supporting part. The supporting part is arranged on the medicine bin, and the medicine bin is limited in the vagina of the animal through the supporting part, so that the medicine bin corresponds to the cervix orifice, and long-term stable sustained-release administration operation is achieved.

Description

TECHNICAL FIELD

[0001] The present application relates to a drug delivery device for livestock breeding, in particular to an animal cervix sustained-release drug delivery device. BACKGROUND

[0002] In livestock breeding, the drug delivery method for animals varies according to the different action sites. In addition to the conventional oral and injection drug delivery, targeted local drug delivery can directly deliver drugs to the lesion area, increase the local drug concentration, and avoid the adverse reactions caused by systemic drug delivery. Compared with systemic drug delivery, local drug delivery has the advantages of fast effect and low cost.

[0003] Currently, artificial insemination is gradually replacing the traditional natural reproduction mode in livestock breeding, and therefore, the uterus as the main reproductive organ needs to receive more targeted drug delivery operations during artificial insemination, such as using progestins for synchronization of estrus and diestrus, and using antibiotics for the treatment of reproductive organ inflammation.

[0004] The commonly used targeted drug delivery devices currently mainly include sponge plugs, catheter type tampons, and "Y" shaped plugs, but these devices generally have the problems of poor placement comfort and easy falling off. Among them, the sponge plug has a high falling off rate of about 10%, and the falling off rate of the catheter type tampon and the "Y" shaped plug is about 5%. The conventional "Y" shaped plug has its head outward during placement, and in order to prevent falling off, it needs to have a high hardness, which further aggravates the discomfort of the animal.

[0005] In addition, in order to maintain the sustained release of the drug, the above-mentioned devices need to be left in the animal body for a long time. However, sponge plugs and catheter type tampons are easy to block the vagina, causing the retention of secretions, and further causing inflammation or adhesion. SUMMARY

[0006] The present application is an animal cervix sustained-release drug delivery device, which is provided with a support part on the drug cartridge, the support part limits the drug cartridge in the vagina of the animal, so that the drug cartridge corresponds to the cervix, and realizes long-term stable sustained-release drug delivery operation.

[0007] The present application adopts the following technical solutions: An animal cervix sustained-release drug delivery device, which comprises a drug cartridge and a support part, the drug cartridge is in a columnar structure, the support part is arranged at the rear part of the drug cartridge, the support part is in a whole bracket type structure, and a traction part is further arranged on the support part, the traction part tracts the folding of the support part.

[0008] The medicine bin end is provided with a conical protrusion, the center of the medicine bin is provided with a hollow cavity, the front end of the medicine bin is provided with a front release hole, the two sides of the cavity bottom of the medicine bin are also provided with left and right rear release holes, the front release hole and the rear release hole are respectively provided with a cotton thread guide; the medicine bin is made of silica gel material, a cylindrical groove is arranged at the bottom of the medicine bin, the end of the support part is provided with a cylindrical connecting head corresponding to the groove, and the support part is inserted into the groove of the medicine bin to realize the connection of the two; a plurality of anti-dropping lines are arranged on the connecting head.

[0009] The support part further includes a support leg, which is arranged at the lower part of the connecting head, and a plurality of support legs are uniformly distributed below the connecting head, the support legs extend outward in a scattering manner below the connecting head, the support legs are made of elastic material, including but not limited to thin steel wires; the outer part of the support leg is wrapped with a silica gel sleeve; the traction part includes a pull wire corresponding to the support leg, and the pull wire pulls the tail end of the support leg to the center to realize the folding operation of the support leg.

[0010] The traction part further includes a movable top rod, the top rod is a tubular structure, the end of the top rod is provided with a notched groove corresponding to the pull wire, and when the end of the top rod is movably supported at the bottom of the connecting head, the notched groove corresponds to the range where the support leg is located.

[0011] Further, the traction part includes a ring-shaped bracket, the bracket is arranged at the center of the tail end of the support leg, the bracket and the connecting head are concentric structures, one end of the pull wire is connected to the support leg, and the other end is connected to the bracket; the traction part further includes a movable traction rod, the traction rod supports or pulls the bracket to drive the pull wire, and then drives the tail end of the support leg to the center.

[0012] The traction rod includes an inner rod and an outer rod, the outer rod is a hollow tubular structure, the inner rod is inserted into the outer rod, the diameter of the inner rod corresponds to the diameter of the center hole on the bracket, and the outer rod is supported on the end face of the bracket; the end of the inner rod is provided with a hook, and the bottom center of the connecting head is provided with a hook corresponding to the hook; the inner rod of the traction rod passes through the bracket and is connected to the hook on the connecting head, the outer rod is pushed to the connecting head direction to support the bracket to the inside, and drives the tail end of the pull wire and the support leg to the center.

[0013] The traction rod comprises an inner rod and an outer rod, the outer rod is a hollow tubular structure, the inner rod is inserted into the outer rod, and the front end of the inner rod is provided with a same diameter section with the same outer diameter as the outer rod; the inner rod slides in the outer rod, and when the same diameter section is attached to the end of the outer rod, the same diameter section and the outer rod form a complete columnar structure, and are synchronously inserted into the center hole on the bracket; the outer rod is provided with a limiting tooth for limiting the bracket, the inner rod and the outer rod are jointly inserted into the center hole on the bracket, the same diameter section at the end of the inner rod is supported to the bottom of the connecting head, and the corresponding limiting tooth on the outer rod limits the inner side of the bracket; the sliding of the outer rod to the outer side drives the bracket and the pull wire to stretch to the outer side, so that the supporting legs are close to the center.

[0014] Further, the end of the outer rod is provided with a ring-shaped step groove, the corresponding same diameter section is provided with a ring-shaped insertion groove, the step groove is inserted into the insertion groove when the end of the outer rod is butted against the same diameter section, the limiting tooth on the outer rod corresponds to the step groove part, and the limiting tooth is retracted into the insertion groove under the limitation of the outer side wall of the insertion groove when the step groove is inserted into the insertion groove; the end of the outer rod is provided with a strip-shaped notch part consistent with the direction of the outer rod, the step groove occupies part of the notch part, the notch part is provided with a reed, the end of the reed is provided with the limiting tooth, the limiting tooth is wedge-shaped as a whole, and the reed and the corresponding limiting tooth correspond to the overall outer edge of the outer rod; a space is left between the bottom of the reed and the inner wall of the outer rod for the movement of the limiting tooth to the inner side.

[0015] The present application has the following beneficial effects: The corresponding support part structure of the present application can maintain a stable support position in the uterus of an animal, facilitates long-term drug release operation of the drug bin, and adopts a pull wire type closing mode for the supporting leg structure of the support part, so that good dismounting effect can be achieved when the present device is taken out after the completion of drug release, and the uterus of the animal is not damaged.

[0016] The present application provides a new design scheme for the slow-release drug delivery of the uterus of an animal, and actual verification shows that the present application is several times more than the conventional directional drug delivery device in placement time, so that a more optimal idea is provided for the design of the amount of drug and the drug slow-release period. BRIEF DESCRIPTION OF DRAWINGS

[0017] Figure 1 The present application is a schematic diagram of embodiment 1.

[0018] Figure 2 The present application is a sectional view of the drug bin and the support part of embodiment 1.

[0019] Figure 3 The present application is a schematic diagram of embodiment 2.

[0020] Figure 4 The present application is a partial schematic diagram in Figure 3 ​

[0021] Figure 5 This is a schematic diagram of Example 3.

[0022] Figure 6 This is a schematic diagram showing the breakdown of Example 3.

[0023] Figure 7 This is a schematic diagram of the limiting teeth. Detailed Implementation

[0024] The present invention will be further described below with reference to the accompanying drawings and embodiments. It should be understood that the following embodiments are only one or more manifestations of the present invention and are not a complete limitation on the invention content described in this application. Any improvements made based on the invention content or technical solution described in this application that are known to those skilled in the art should fall within the scope of protection claimed in this application.

[0025] Furthermore, the descriptions of directions such as up, down, left, right, front, and back presented in the specific embodiments are merely for the purpose of describing the technical solutions and are not absolute limitations unless otherwise stated.

[0026] like Figure 1 , Figure 2 The present invention relates to a sustained-release drug delivery device for animal cervix, comprising a drug chamber 1 and a support part 2. The drug chamber 1 is a columnar structure, and the support part 2 is located at the rear of the drug chamber 1. The support part 2 is a bracket structure, and a traction part 3 is provided on the support part 2, which pulls the support part 2 to close.

[0027] The drug chamber 1 has a conical protrusion 101 at one end, a hollow cavity 102 at the center, a through front release hole 1031 at the front end, and through rear release holes 1032 on both sides of the bottom of the cavity 102. Cotton thread guides 105 are respectively provided in the front release hole 1031 and the rear release hole 1032. The drug chamber 1 is made of silicone material. A columnar groove 104 is provided at the bottom of the drug chamber 1. The end of the support part 2 is provided with a columnar connector 201 corresponding to the groove 104. The support part 2 is connected to the groove 104 of the drug chamber 1 by inserting the connector 201 into the groove 104 of the drug chamber 1. The connector 201 is also provided with several anti-slip textures 202, which are recessed groove structures.

[0028] The support part 2 further comprises a supporting leg 203 arranged at the lower part of the connecting head 201, and a plurality of supporting legs 203 are uniformly arranged below the connecting head 201, the supporting legs 203 extend outward in a scattered manner below the connecting head 201, the supporting legs 203 are made of elastic material, including but not limited to thin steel wires; the outer part of the supporting leg 203 is wrapped with a silica gel sleeve 204; the traction part 3 comprises a pull wire 301 corresponding to the supporting leg 203, and the pull wire 301 pulls the supporting leg 203 to make the tail end of the supporting leg 203 close to the center to realize the folding operation of the supporting leg 203.

[0029] The above is the basic design idea of the case, and the following three specific design schemes are provided as further refinement, which mainly explain and illustrate the specific operation mode of the traction part. Embodiment 1

[0030] As shown in Figure 1 and Figure 2 , the pull wire 301 is provided with a plurality of pull wires 301 corresponding to the supporting leg 203, the pull wire 301 is connected to the tail of the supporting leg 203 respectively, and the free end of the pull wire 301 is gathered into one pull wire 301 extending outward at the center of the supporting leg 203; the traction part 3 further comprises a movable top rod 302, the top rod 302 is a tubular structure, the end of the top rod 302 is provided with a notch groove 3021 corresponding to the pull wire 301, and when the end of the top rod 302 is movably supported at the bottom of the connecting head 201, the pull wire 301 is correspondingly arranged in each notch groove 3021.

[0031] The design mode of the pull wire in this embodiment is relatively simple, only the tail end of the supporting leg is connected by the pull wire, and the supporting leg is closed to the center by pulling the pull wire to close, so that the supporting leg is relatively closed when the device is taken out, and the uterus is not damaged, and when the pull wire is not pulled, the supporting leg is scattered and supported in the vagina of the animal to prevent it from coming out.

[0032] In order to further facilitate the taking out operation of the device after use, a top rod device is added in this example, in actual operation, the top rod can be inserted into the vagina, the notch groove at the end of the top rod is correspondingly arranged in the pull wire in different directions and inserted, then the end of the top rod is supported at the bottom of the connecting head, the total pull wire is pulled out from the top rod, at this time, the total pull wire is pulled, the top rod is relatively fixed with the connecting head, the total pull wire drives each pull wire to enter the fixed rod from the notch groove and move outward, at the same time, the tail end of the supporting leg closes to the top rod, the folding operation of the supporting part is realized, when the top rod device is not arranged, the pulling of the pull wire will drive the whole movement of the supporting part and the medicine bin, the relative folding effect is not good, the intervention of the top rod makes the supporting part first realize the folding, and then is taken out, which causes less damage to the animal. Embodiment 2

[0033] As shown in Figure 3 andFigure 4 As shown, the traction part 3 comprises a ring-shaped bracket 303, which is arranged at the center of the tail end of the supporting leg 203, and the bracket 303 is concentric with the connecting head 201. One end of the pull wire 301 is connected to the supporting leg 203, and the other end is connected to the bracket 303. The traction part 3 further comprises a movably arranged traction rod 304, which supports or pulls the bracket 303 to drive the pull wire 301, thereby driving the tail end of the supporting leg 203 to move towards the center.

[0034] The traction rod 304 comprises an inner rod 3041 and an outer rod 3042. The outer rod 3042 is a hollow tubular structure, and the inner rod 3041 is inserted into the outer rod 3042. The diameter of the inner rod 3041 corresponds to that of the center hole of the bracket 303, and the outer rod 3042 is supported on the end face of the bracket 303. The end of the inner rod 3041 is provided with a hook 3043, and the bottom center of the connecting head 201 is provided with a corresponding hook 3044. The inner rod 3041 of the traction rod 304 passes through the bracket 303 and is connected to the hook 3044 of the connecting head 201 through the hook 3043. Pushing the outer rod 3042 towards the connecting head 201 supports the bracket 303 from the inside, thereby driving the pull wire 301 and the tail end of the supporting leg 203 to move towards the center.

[0035] The above is another embodiment of the present application. In this embodiment, a bracket is arranged at the center of the pull wire to uniformly connect the pull wire. The inner end of the corresponding pull wire of the supporting leg is connected to the bracket. At this time, the movement of the bracket position can drive the pull wire. This structure eliminates the need for pull wire structures that extend to the outside. Overall, the use effect is better. In combination with the corresponding traction rod, the corresponding folding operation can be achieved. In this example, the bracket is pushed towards the connecting head to drive the supporting leg to fold. The inner rod is limited by the hook, and then the outer rod is pushed inwards to support the bracket from the inside to achieve the desired effect.

[0036] In actual use, this structure still has room for improvement. The pushing method is not convenient for single-handed operation, so the next embodiment is introduced. Embodiment 3

[0037] As Figures 5-7As shown, the traction rod 304 includes an inner rod 3041 and an outer rod 3042, the outer rod 3042 is a hollow tubular structure, the inner rod 3041 is inserted into the outer rod 3042, and the front end of the inner rod 3041 is provided with a same diameter section 305 with the same outer diameter as the outer rod 3042, the inner rod 3041 slides in the outer rod 3042, and when the same diameter section 305 is attached to the end of the outer rod 3042, the same diameter section 305 and the outer rod 3042 form a complete columnar structure, and both are synchronously inserted into the center hole on the bracket 303; The outer rod 3042 is provided with a limiting tooth 306 for limiting the bracket 303, the inner rod 3041 and the outer rod 3042 are inserted into the center hole on the bracket 303, the same diameter section 305 at the end of the inner rod 3041 supports the bottom of the connector 201, the corresponding limiting tooth 306 on the outer rod 3042 limits the inner side of the bracket 303, and the sliding of the outer rod 3042 to the outside side drives the bracket 303 and the pull wire 301 to stretch outward to realize the convergence of the supporting legs 203 to the center.

[0038] Further, the outer edge of the end of the outer rod 3042 is provided with a ring-shaped step groove 3045, and the corresponding same diameter section 305 is provided with a ring-shaped insertion groove 3051, when the end of the outer rod 3042 is connected to the same diameter section 305, the step groove 3045 is inserted into the insertion groove 3051, the limiting tooth 306 on the outer rod 3042 corresponds to the step groove 3045, and when the step groove 3045 is inserted into the insertion groove 3051, the limiting tooth 306 is retracted into the insertion groove 3051 under the limitation of the outer side wall of the insertion groove 3051; The end of the outer rod 3042 is provided with a strip-shaped notch portion 3046 consistent with its own direction, the step groove 3045 occupies part of the notch portion 3046, the notch portion 3046 is provided with a reed 3047, the end of the reed 3047 is provided with the limiting tooth 306, the limiting tooth 306 is wedge-shaped as a whole, and the reed 3047 and the corresponding limiting tooth 306 correspond to the overall outer edge of the outer rod 3042, and there is a space between the bottom of the reed 3047 and the inner wall of the outer rod 3042 for the inward movement of the limiting tooth 306.

[0039] The application adopts the structure of pulling the bracket outward to realize folding, the inner rod and the outer rod are designed as the structure of mutual sliding insertion, and both can be inserted as the complete cylindrical structure corresponding to the center hole of the bracket, during use, the both are inserted, the stepped groove of the outer rod is inserted into the insertion slot on the same diameter section, during the insertion process, the outer wall of the insertion slot presses the limiting teeth downward to make it shrink into the insertion slot, at this time, the complete cylinder formed by the inner rod and the outer rod can be inserted into the center hole on the bracket, then, the tail ends of the inner rod and the outer rod are pressed mutually to make them slide mutually, the end part of the outer rod is separated from the insertion slot, the limiting teeth and the spring leaf lose the limitation to stretch outward, and are higher than the outer edge of the outer rod, at this time, the continuous pressing is carried out, the top of the inner rod supports the bottom of the connecting head, and is limited to the inner side of the bracket, drives it to move away from the connecting head, the bracket drives the pull wire and the supporting leg to move close to the center, and realizes the folding operation of the supporting leg, the biggest advantage of the pressing operation type structure of the application is that the single hand operation can be realized, and the device can be used to realize the installation and removal of the whole medicine dispenser.

Claims

1. A sustained-release drug delivery device for animal cervix, characterized in that: It includes a drug compartment and a support section. The drug compartment is a columnar structure, and the support section is located at the rear of the drug compartment. The support section is a bracket structure, and a traction section is also provided on the support section. The traction section pulls the support section to close.

2. The animal cervical sustained-release drug delivery device according to claim 1, characterized in that: The drug chamber has a conical protrusion at its end and a hollow cavity at its center. A through-hole is located at the front end of the drug chamber, and through-holes are located on both sides of the bottom of the cavity. Cotton thread guides are installed inside both the front and rear release holes. The entire drug chamber is made of silicone material, with a columnar groove at its bottom. A columnar connector corresponding to the groove is located at the end of the support part. The support part is connected to the groove of the drug chamber via the connector. The connector also has several anti-slip grooves, which are recessed groove structures.

3. The animal cervical sustained-release drug delivery device according to claim 2, characterized in that: The support unit also includes legs, which are located at the lower part of the connector. Several legs are evenly distributed below the connector and extend outwards in a radiating pattern. The legs are made of elastic material, including but not limited to thin steel wire. The legs are covered with silicone sleeves. The traction unit includes pull lines corresponding to the legs. The pull lines pull the legs so that their ends move towards the center to achieve the retraction operation of the legs.

4. The animal cervical sustained-release drug delivery device according to claim 3, characterized in that: The pull cable has several corresponding to the outriggers, and the pull cables are respectively connected to the tail of the outriggers. The free ends of the pull cables converge at the center of the outriggers to form a pull cable extending outward. The traction part also includes a movable top rod. The top rod is a tubular structure. The end of the top rod has a notch corresponding to the pull cable. When the end of the top rod is movably supported to the bottom of the connector, the notch corresponds to the area where the outrigger is located.

5. The animal cervical sustained-release drug delivery device according to claim 3, characterized in that: The traction unit includes an annular bracket located at the center of the tail end of the outrigger. The bracket and the connector are concentric. One end of the pull cable is connected to the outrigger, and the other end is connected to the bracket. The traction unit also includes a movable traction rod, which supports or pulls the bracket to drive the pull cable, thereby causing the end of the outrigger to move closer to the center.

6. The animal cervical sustained-release drug delivery device according to claim 5, characterized in that: The traction rod includes an inner rod and an outer rod. The outer rod is a hollow tubular structure. The inner rod is inserted into the outer rod, and the diameter of the inner rod corresponds to the diameter of the central hole on the bracket. The outer rod is supported on the end face of the bracket. The end of the inner rod is provided with a hook, and the bottom center of the connector is provided with a buckle corresponding to the hook. After the inner rod on the traction rod passes through the bracket, it is connected to the buckle on the connector through the hook. Pushing the outer rod towards the connector makes it support the bracket inward, causing the tail of the pull cable and the support leg to move closer to the center.

7. The animal cervical sustained-release drug delivery device according to claim 5, characterized in that: The traction rod includes an inner rod and an outer rod. The outer rod is a hollow tubular structure, and the inner rod is inserted inside the outer rod. The front end of the inner rod has a section with the same outer diameter as the outer rod. The inner rod slides inside the outer rod until the section with the same diameter fits against the end of the outer rod, forming a complete columnar structure. Both are simultaneously inserted into the central hole on the bracket. The outer rod has limiting teeth that limit the bracket. The inner rod and the outer rod are inserted into the central hole on the bracket together. The section with the same diameter at the end of the inner rod supports the bottom of the connector. The corresponding limiting teeth on the outer rod limit the inner side of the bracket. The sliding of the outer rod outward causes the bracket and the pull cable to stretch outward, so that the outriggers move closer to the center.

8. The animal cervical sustained-release drug delivery device according to claim 7, characterized in that: The outer rod has an annular stepped groove along its outer edge, and a corresponding annular slot along its diameter. When the outer rod is aligned with the diameter section, the stepped groove is inserted into the slot. The limiting tooth on the outer rod corresponds to the stepped groove. When the stepped groove is inserted into the slot, the limiting tooth retracts into the slot due to the limiting effect of the outer wall of the slot. The outer rod has a strip-shaped notch that is aligned with its own direction. The stepped groove occupies part of the notch. A spring is provided in the notch. The end of the spring is provided with the limiting tooth. The limiting tooth is wedge-shaped, and the spring and the corresponding limiting tooth correspond to the outer edge of the outer rod. There is space between the bottom of the spring and the inner wall of the outer rod for the limiting tooth to move inward.

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