Honeysuckle flower extract and preparation method thereof

Abstract

The invention provides a preparation method of a honeysuckle flower extract. The preparation method comprises the following steps: S1, material selection: selecting honeysuckle flowers which are picked in a flower bud stage and of which the water content is controlled to be 12% or below; s2, impurity removal: removing impurities in the honeysuckle flowers, and removing non-medicinal parts; s3, cleaning: cleaning and draining the honeysuckle flowers; s4, cutting: cutting the honeysuckle raw material to destroy the cell structure; s5, sterilization: sterilizing the cut honeysuckle raw materials; and S6, screening: screening the cut honeysuckle raw materials, and screening out honeysuckle scraps of 80 meshes or above. The extraction method adopted by the invention is simple, the extract yield of the honeysuckle extract can be effectively improved, no other materials are added in the whole process, and the cost and manpower are effectively saved.

Description

TECHNICAL FIELD

[0001] The present application relates to the extraction and processing technology field of honeysuckle, and in particular to a honeysuckle extract and a preparation method thereof. BACKGROUND

[0002] Honeysuckle is a perennial semi-evergreen climbing shrub of Caprifoliaceae Lonicera, which is famous for its unique yellow and white flowers and excellent medicinal value. Its main function is to clear heat and detoxify, and it is especially effective in treating wind-heat cold, sore throat and other aspects, and is known as "Chinese antibiotic". After a series of processing such as decoction, the extract can be obtained, which is extract, but the current preparation method of honeysuckle extract has low extraction rate. SUMMARY

[0003] The present application discloses a honeysuckle extract and a preparation method thereof, which solves the problem of low extraction rate of the current preparation method of honeysuckle extract.

[0004] To solve the above technical problems, the present application specifically adopts the following technical solutions:

[0005] A honeysuckle extract preparation method, characterized in that it comprises the following steps:

[0006] S1, selecting material: selecting and picking up the flower bud stage, and controlling the water content below 12% of the honeysuckle;

[0007] S2, impurity removal: removing impurities in the honeysuckle and rejecting non-medicinal parts;

[0008] S3, cleaning: cleaning the honeysuckle and draining;

[0009] S4, cutting: cutting the honeysuckle raw material to destroy the cell structure;

[0010] S5, sterilization: sterilizing the cut honeysuckle raw material;

[0011] S6, screening: screening the cut honeysuckle raw material, and screening out honeysuckle debris above 80 meshes;

[0012] S7, soaking: soaking the honeysuckle raw material in water to open the honeysuckle raw material;

[0013] S8, first decoction: taking out the honeysuckle raw material from the water, adding pure water to decoct, controlling the water temperature at 95-100 DEG C, and decocting for 2-3 hours;

[0014] a, collecting the water vapor generated in the first decoction process of the honeysuckle raw material to form a pure distillate;

[0015] b, oil-water separation of the pure distillate to obtain honeysuckle essential oil and distillate water;

[0016] S9, filtering: separating the boiled honeysuckle raw materials from water to obtain an extract;

[0017] S10, second boiling: putting the honeysuckle raw materials after the first boiling into pure water for second boiling, with the temperature controlled at 95-110°C, and the boiling time being 1-1.5 hours;

[0018] a, collecting the water vapor generated in the second boiling process of the honeysuckle raw materials to form a hydrolat;

[0019] b, separating the hydrolat into honeysuckle essential oil and distillate water;

[0020] S11, separating: separating the honeysuckle raw materials after the second boiling from water to obtain an extract;

[0021] S12, mixing: mixing the extracts obtained by the two extractions together;

[0022] S13, sieving: sieving the mixed extract to remove the particulate impurities in the extract;

[0023] S14, vacuum concentrating the extract to obtain honeysuckle extract.

[0024] Further, the honeysuckle raw materials are soaked in water for 3-5 hours to completely open the honeysuckle raw materials.

[0025] Further, the amount of water added in the first boiling of the honeysuckle raw materials is 8-10 times that of the honeysuckle raw materials.

[0026] Further, the amount of water added in the second boiling of the honeysuckle raw materials is 6-8 times that of the honeysuckle raw materials.

[0027] Further, the specific gravity of the honeysuckle extract obtained after vacuum concentration to the honeysuckle raw materials is 1:1-1.3.

[0028] Further, the distillate water is mixed with pure water to boil the next batch of honeysuckle.

[0029] A honeysuckle extract prepared by any of the preparation methods of the present application.

[0030] Compared with the prior art, the present application has the following beneficial effects:

[0031] The extraction method adopted by the present application is simple, can effectively improve the extract yield of honeysuckle extract, and the whole process does not need to add any other materials, effectively saving the cost and manpower. DETAILED DESCRIPTION

[0032] The specific content of the present application will be described in detail below in conjunction with examples.

[0033] Embodiment 1:

[0034] A preparation method of honeysuckle extract, comprising the following steps:

[0035] S1, take 100 kg of dry honeysuckle raw materials, preferably honeysuckle raw materials picked at the bud stage ("two white period" or "large white period"), and honeysuckle raw materials with water content controlled below 12%; high water content is easy to cause mold and enzymatic hydrolysis of active ingredients, and also affects the subsequent solvent penetration and concentration energy consumption;

[0036] S2, remove large impurities such as branches, leaves, soil, sand, etc. through a vibrating screen or an air separator; remove non-medicinal parts (such as open flowers, blackened, moldy, and worm-eaten flower buds) and foreign colors by hand or a color sorter, while removing possible metal shavings;

[0037] S3, clean the selected honeysuckle raw materials and quickly drain them through an air dryer;

[0038] S4, cut the honeysuckle raw materials, cut one part of the honeysuckle raw materials into two parts, destroy the cell structure of the honeysuckle raw materials, increase the contact area with the extraction solvent, and greatly improve the mass transfer rate and extraction rate;

[0039] S5, irradiate the honeysuckle raw materials with cobalt-60 gamma rays or electron beams for sterilization;

[0040] S6, screen out honeysuckle raw material debris above 80 mesh to avoid difficulty in later filtration, increase the impurities of the extract, and reduce the clarity;

[0041] S7, soak the honeysuckle raw materials in water for 5 hours to open the honeysuckle raw materials;

[0042] S8, take the honeysuckle out of the water, then add 1000 kg of pure water to cook, control the water temperature at 95℃, and cook for 3 hours; the water vapor is transported to the collection cylinder through the pipeline to form pure incense;

[0043] S9, use suction filtration to filter through a 200-mesh screen to separate the cooked honeysuckle and pure water, and obtain a clear extract;

[0044] S10, put the honeysuckle raw materials after the first cooking into 800 kg of pure water for secondary cooking, control the temperature at 100℃, and cook for 1.5 hours; the water vapor generated during the second cooking of the honeysuckle raw materials is also collected;

[0045] S11, use suction filtration to filter through a 150-mesh screen to separate the honeysuckle after secondary cooking and pure water, and obtain a clear extract;

[0046] S12, stirring and mixing the twice extracted extract to make the components uniformly distributed;

[0047] S13, passing the mixed extract through a 100 mesh screen to further remove impurities in the extract;

[0048] S14, using a pure electric concentrator to concentrate the extract, temperature 60℃, vacuum degree-0.06Mpa, concentrated to relative density 1.06-1.08g / ml(60℃), filtered through a 300 mesh screen to prepare the extract; the pure extract is separated by oil-water separation equipment, and the honeysuckle essential oil is collected and stored. The distilled water is collected and then added to the next batch of honeysuckle decoction for recycling.

[0049] Example 2:

[0050] A honeysuckle extract preparation method, comprising the following steps:

[0051] S1, take 100kg of dry honeysuckle raw materials, preferentially select honeysuckle raw materials picked at the bud stage (“two white period” or “large white period”), and honeysuckle raw materials with water content below 12%; high water content is easy to cause mold and enzyme hydrolysis of active ingredients, and also affects the subsequent solvent penetration and concentration energy consumption;

[0052] S2, remove large impurities such as branches, leaves, dirt, sand, etc. by vibration screen or air separator; manually or by color sorter to remove non-medicinal parts (such as open flowers, blackened, moldy, worm-eaten flower buds) and foreign colors, while removing possible metal shavings;

[0053] S3, clean the selected honeysuckle raw materials and quickly drain them through an air dryer;

[0054] S4, cut the honeysuckle raw materials, cut one part of the honeysuckle raw materials into two parts, destroy the cell structure of the honeysuckle raw materials, increase the contact area with the extraction solvent, and greatly improve the mass transfer rate and extraction rate;

[0055] S5, irradiate the honeysuckle raw materials with cobalt-60 gamma rays or electron beams for sterilization;

[0056] S6, screen out honeysuckle raw material debris above 80 mesh to avoid difficulty in later filtration, increase the impurities of the extract, and reduce the clarity;

[0057] S7, soak the honeysuckle raw materials in water for 5 hours to open the honeysuckle raw materials;

[0058] S8, the honeysuckle is taken out from the water, then 800 kg of pure water is boiled, the water temperature is controlled at 100℃, and the boiling time is 2.5 hours; the water vapor is transported into the collection cylinder through the pipeline to form the hydrolat;

[0059] S9, the boiling honeysuckle and the pure water are separated by adopting the way of suction filtration and filtering through a 200-mesh screen to obtain the clear extract;

[0060] S10, the honeysuckle raw material after the first boiling is put into 600 kg of pure water for secondary boiling, the temperature is controlled at 110℃, and the boiling time is 1 hour; the water vapor generated in the second boiling process of the honeysuckle raw material is also collected;

[0061] S11, the secondary boiled honeysuckle and the pure water are separated by adopting the way of suction filtration and filtering through a 150-mesh screen to obtain the clear extract;

[0062] S12, the extract liquids extracted twice are stirred and mixed to make the components uniformly distributed;

[0063] S13, the mixed extract liquid is filtered through a 100-mesh screen to further remove the impurities in the extract liquid;

[0064] S14, the extract liquid is concentrated by using a pure electric concentrator, the temperature is 60℃, the vacuum degree is -0.06 Mpa, the concentration is to the relative density of 1.06-1.08 g / ml (60℃), the filtration is through a 300-mesh screen to prepare the extract; the hydrolat is separated by the oil-water separation equipment, then the honeysuckle essential oil is collected and stored, the distilled water is led out and collected, and then it is supplemented to the honeysuckle boiling of the next batch for recycling.

[0065] Comparative Example 1:

[0066] The comparative example provides a preparation method of honeysuckle extract, which specifically includes the following steps:

[0067] (1) 100 kg of honeysuckle is taken, 800 kg of water is added, and the temperature is raised to 100℃, and boiled for 3 hours;

[0068] (2) the decoction liquid is filtered through an 80-mesh screen, and the filtrate and the dregs are collected;

[0069] The extract yield of comparative example 1 is 70 kg ~ 100 kg.

[0070] The extract yield of extract examples 1-2 and extract comparative example 1 is calculated after weighing;

[0071] Example 1:

[0072] First boiling:

[0073] Water added: 1000 kg;

[0074] Boiling time: 3 hours;

[0075] Evaporation rate per hour 10%: 1000 kg x 10% = 100 kg / hour;

[0076] Total evaporation = 100 kg / hour x 3 hours = 300 kg;

[0077] First filtered medicinal liquid mass = water added mass - evaporation + dissolved substance mass

[0078] Raw material dissolved substance = 40 kg;

[0079] First medicinal liquid mass = 1000 - 300 + 40 = 740 kg;

[0080] Second boiling;

[0081] Water added: 800 kg;

[0082] Boiling time: 1.5 hours;

[0083] Evaporation rate per hour: 800 kg x 10% = 80 kg / hour;

[0084] Total evaporation = 80 kg / hour x 1.5 hours = 120 kg;

[0085] Second dissolved substance is 1 / 3 of the first, 15 kg;

[0086] Second medicinal liquid mass = 800 - 120 + 15 = 695 kg;

[0087] Total medicinal liquid mass = 740 + 695 = 1435 kg; After concentration, 115 kg of extract is obtained.

[0088] Example 2:

[0089] First boiling:

[0090] Water added: 8000 kg;

[0091] Boiling time: 2.5 hours;

[0092] Evaporation rate per hour 10%: 1000 kg x 10% = 100 kg / hour;

[0093] Total evaporation = 800 kg x 10% x 2.5 = 200 kg;

[0094] First filtered medicinal liquid mass = water added mass - evaporation + dissolved substance mass

[0095] Dissolved material of raw material = 30 kg;

[0096] First time medicinal liquid mass = 800 - 200 + 30 = 630 kg;

[0097] Second time boiling;

[0098] Water added amount: 600 kg;

[0099] Boiling time: 1 hour;

[0100] Evaporation rate per hour: 800 kg x 10% = 80 kg / hour;

[0101] Total evaporation amount = 600 kg x 10% x 1 = 60 kg;

[0102] Second time dissolved material is 12 kg;

[0103] Second time medicinal liquid mass = 600 - 60 + 12 = 552 kg;

[0104] Total medicinal liquid mass = 630 + 552 = 1182 kg; 105 kg of extract is obtained after concentration.

[0105] Finally, it is to be noted that the above examples are merely used to illustrate the technical solutions of the present application and not to limit the same. Although the present application has been described in detail with reference to the preferred embodiments, those skilled in the art should understand that the technical solutions of the present application can be modified or replaced equivalently without departing from the spirit and scope of the present application, and all of them should be covered in the scope of the claims of the present application.

Claims

1. A preparation method of honeysuckle extract, characterized in that, It comprises the following steps: S1, selecting: selecting and picking at the bud stage, and the moisture control is below 12% of honeysuckle; S2, impurity removal: removing impurities in honeysuckle, and rejecting non-medicinal parts; S3, cleaning: cleaning honeysuckle and draining; S4, cutting: cutting honeysuckle raw materials, destroying cell structure; S5, sterilization: sterilizing honeysuckle raw materials after cutting; S6, screening: screening honeysuckle raw materials after cutting, and screening out honeysuckle debris above 80 meshes; S7, soaking: soaking honeysuckle raw materials in water, and opening honeysuckle raw materials; S8, first boiling: after taking honeysuckle raw materials out of water, boiling with pure water, water temperature is controlled at 95-100℃, and boiling time is 2-3 hours; a, collecting water vapor generated in the first boiling process of honeysuckle raw materials to form hydrolate; b, oil-water separation of hydrolate to obtain honeysuckle essential oil and distillate water; S9, filtering: separating honeysuckle raw materials after boiling from water to obtain extract; S10, second boiling: putting honeysuckle raw materials after the first boiling into pure water for second boiling, temperature control is 95-110℃, and boiling time is 1-1.5 hours; a, collecting water vapor generated in the second boiling process of honeysuckle raw materials to form hydrolate; b, oil-water separation of hydrolate to obtain honeysuckle essential oil and distillate water; S110, separation: separating honeysuckle raw materials after second boiling from water to obtain extract; S12, mixing: mixing extractives extracted twice together; S13, sieving: sieving extractives mixed together to remove particulate impurities in extractives; S14, vacuum concentration of extractives to obtain honeysuckle extract. 2.The honeysuckle extract and a preparation method thereof according to claim 1, characterized in that: Honeysuckle raw materials are soaked in water for 3-5 hours to completely open honeysuckle raw materials. 3.The honeysuckle extract and a preparation method thereof according to claim 1, characterized in that: The amount of water added in the first boiling of honeysuckle raw materials is 8-10 times of honeysuckle raw materials. 4.The honeysuckle extract and a preparation method thereof according to claim 1, characterized in that: The amount of water added in the second boiling of honeysuckle raw materials is 6-8 times of honeysuckle raw materials. 5.The honeysuckle extract and a preparation method thereof according to claim 1, characterized in that: The specific gravity of honeysuckle extract obtained after vacuum concentration to honeysuckle raw materials is: 1; 1-1.

3. 6.The honeysuckle extract and a preparation method thereof according to claim 1, characterized in that: Distillate water is mixed in pure water to boil the next batch of honeysuckle.

7. A honeysuckle extract prepared by the preparation method of any one of claims 1-6.