Plant essential oil intestinal tract conditioner for ornamental birds

Abstract

According to the plant essential oil intestinal conditioner for the ornamental birds, a pure plant essential oil formula is adopted to achieve a sterilization effect, and the plant essential oil intestinal conditioner is safer and more harmless to the health of the ornamental birds. According to the present invention, the problems of easy volatilization, easy loss, poor palatability, difficult direct taking and the like caused by the pure use of the plant essential oil are reduced, and the plant essential oil is used for inhibiting harmful bacteria in flora in the digestive tract of the ornamental bird so as to provide effects of growth promotion, weight increase and antibiotic use reduction for the ornamental bird.

Description

Technical Field

[0001] This invention relates to the field of poultry medicine technology, specifically to a plant essential oil intestinal conditioner for ornamental birds. Background Technology

[0002] Based on records of various digestive tract diseases in several herbivorous ornamental birds, including small and medium-sized parrots and Java sparrows, as documented in publications such as *Chinese Avian Diseases (2nd Edition)*, *Veterinary Pharmacology*, *Feed Additives: Aromatic and Herbal Plants and Their Extracts for Animal Nutrition and Health*, and *Aromatherapy for Parrots*, as well as the inventor's many years of clinical experience, enteritis, one of the most common diseases in captive-bred parrots, is most commonly treated with antibiotics. However, due to the small size and light weight of birds, antibiotic use can easily lead to overdose and cause significant harm to the birds. Summary of the Invention

[0003] To address the shortcomings and deficiencies of existing technologies, this invention provides a plant essential oil intestinal conditioner for ornamental birds, its preparation method, and its application.

[0004] The technical solution adopted in this invention is: a plant essential oil intestinal conditioner for ornamental birds, composed of cinnamon essential oil, thymol, oregano oil, tea tree essential oil and excipients.

[0005] A plant essential oil intestinal conditioner for ornamental birds, composed of 25-35% cinnamon essential oil, 15-25% thymol, 24-34% oregano oil, 5-15% tea tree essential oil, and ≤5 excipients.

[0006] A method for preparing a plant essential oil intestinal conditioner for ornamental birds comprises the following steps: Cinnamon essential oil, thymol, oregano oil, and tea tree essential oil were mixed evenly and then encapsulated using hydroxypropyl β-cyclodextrin via molecular encapsulation. The resulting composite essential oil microcapsule powder was obtained by low-temperature vacuum drying.

[0007] Application of a plant essential oil intestinal conditioner for ornamental birds in the preparation of drugs for treating enteritis in ornamental birds.

[0008] A plant-based antibacterial composition for ornamental birds, comprising the aforementioned plant essential oil intestinal conditioner for ornamental birds and Tween 40.

[0009] Cinnamon essential oil: An aromatic oil obtained by distilling the bark, branches, and leaves of the cinnamon tree. As a major antibacterial agent, it inhibits various bacteria, yeasts, and molds.

[0010] Thymol: Used for sterilization, mainly targeting Gram-negative bacteria such as Salmonella, Bordetella pertussis, and Chlorella vulgaris, as well as Gram-positive bacteria such as Staphylococcus aureus and Listeria monocytogenes.

[0011] Oregano oil: An aromatic oil obtained by distilling oregano branches and leaves, used to combat common bacteria and some fungi.

[0012] Tea tree oil is an essential oil obtained by distilling the leaves and young shoots of the tea tree. It is used to inhibit various bacteria.

[0013] The beneficial effects of this invention are: a plant essential oil intestinal conditioner for ornamental birds. This invention uses a pure plant essential oil formula to achieve a sterilization effect, making it safer and harmless to the health of ornamental birds. This invention reduces the problems caused by simply using plant essential oils, such as volatility, easy loss, poor palatability, and difficulty in direct consumption. This invention is used to inhibit harmful bacteria in the gut microbiota of ornamental birds, thereby promoting their growth, increasing their weight, and reducing the need for antibiotics. Attached Figure Description

[0014] Figure 1 Evaluation of the combined antibacterial performance of plant essential oil intestinal conditioner for ornamental birds and Tween 40 (Clostridium perfringens on the left, Candida albicans on the right).

[0015] Figure 2 The results of the combined antibacterial evaluation experiment of plant essential oil intestinal conditioner for ornamental birds and Tween 40. Detailed Implementation

[0016] The technical solutions of the embodiments of the present invention will be clearly and completely described below with reference to the accompanying drawings. Obviously, the described embodiments are only a part of the embodiments of the present invention, and not all of them. Based on the embodiments of the present invention, all other embodiments obtained by those of ordinary skill in the art without creative effort are within the scope of protection of the present invention.

[0017] Example 1: Preparation of a Plant Essential Oil Intestinal Conditioner for Ornamental Birds 25-35% cinnamon essential oil, 15-25% thymol, 24-34% oregano oil, and 5-15% tea tree essential oil were mixed evenly and then encapsulated using hydroxypropyl β-cyclodextrin via molecular encapsulation. The resulting composite essential oil microcapsule powder was obtained by low-temperature vacuum drying.

[0018] Example 2: An 8-month-old budgie was affected. Before the illness, its droppings were loose, it had no appetite, was inactive, and was losing weight. After 3 days of taking this product, its appetite returned to normal, its spirits returned to normal, and its droppings became formed. After 7 days of treatment, its weight began to increase. There was no change in uric acid color throughout the entire course of treatment.

[0019] Example 3: The affected bird was a 6-month-old cockatoo, weighing approximately 600g. The owner reported vomiting containing mucus and undigested seeds, and loose droppings. The product was administered twice daily at 0.2g each time. After 3 days, the bird's appetite returned to normal, its spirits returned to normal, its droppings became formed, and the vomiting stopped. After 7 days, its weight began to increase.

[0020] Example 4: Evaluation of the combined antibacterial effect of the intestinal conditioner of this invention and Tween 40: (1) Clostridium perfringens No colonies grew in regions A1 to H3 of the 96-well plate used in the experiment. The MIC value of the intestinal conditioner was 0.152 mg / mL, and the MIC value when used in combination was 0.0190 mg / mL; the MIC value of Tween 40 was 195 mg / mL, and the MIC value when used in combination was 24.375 mg / mL. Therefore, the FIC index of Tween 40 and the intestinal conditioner against Clostridium perfringens was calculated to be 0.25.

[0021] Because the FIC is less than 0.5, Tween 40 and intestinal conditioners have a synergistic effect on Clostridium perfringens.

[0022] (2) Candida albicans No colonies grew in wells A1 to B8 of the 96-well plate used in the experiment. The MIC value of the intestinal conditioner was 0.1562 mg / mL, and the MIC value when used in combination was 0.01952 mg / mL; the MIC value of Tween 40 was 195 mg / mL, and the MIC value of Tween 40 when used in combination was 24.375 mg / mL. Therefore, the FIC index of Tween 40 and the intestinal conditioner against Candida albicans was calculated to be 0.25. Since the FIC is less than 0.5, Tween 40 and the intestinal conditioner have a synergistic effect against Candida albicans.

[0023] Instruction manual attached Figure 2 For the checkerboard serial dilution of Clostridium perfringens, the concentrations of the intestinal conditioning agent from column 1 to column 8 were: 0.1525 mg / mL, 0.07625 mg / mL, 0.03812 mg / mL, 0.01906 mg / mL, 0.009531 mg / mL, 0.004766 mg / mL, 0.002383 mg / mL, and 0.001191 mg / mL, respectively; and the concentrations of Tween 40 from column A to column H were: 195.0 mg / mL, 97.50 mg / mL, 48.75 mg / mL, 24.38 mg / mL, 12.19 mg / mL, 6.094 mg / mL, 3.047 mg / mL, and 1.523 mg / mL, respectively.

[0024] The Candida albicans checkerboard serial dilutions, from column 1 to column 8, showed the following concentrations of intestinal conditioning agents: 0.1562 mg / mL, 0.07810 mg / mL, 0.03905 mg / mL, 0.01953 mg / mL, 0.009763 mg / mL, 0.004881 mg / mL, 0.002440 mg / mL, and 0.001220 mg / mL. From column A to column H, the concentrations of Tween 40 were: 195 mg / mL, 97.50 mg / mL, 48.75 mg / mL, 24.38 mg / mL, 12.19 mg / mL, 6.094 mg / mL, 3.047 mg / mL, and 1.523 mg / mL.

Claims

1. A plant essential oil enteral conditioner for ornamental birds, characterized by, Cinnamon essential oil, thymol, oregano oil, tea tree essential oil and adjuvant.

2. The plant essential oil enteral conditioner for ornamental birds according to claim 1, characterized in that, 25-35% cinnamon essential oil, 15-25% thymol, 24-34% oregano oil, 5-15% tea tree essential oil, and ≤5 adjuvant.

3. A method of preparing a plant essential oil enteral conditioner for ornamental birds as claimed in claim 1, wherein, It consists of the following steps: Mix the cinnamon essential oil, thymol, oregano oil, and tea tree essential oil evenly, and use hydroxypropyl β-cyclodextrin to perform molecular inclusion, and use low-temperature vacuum drying method to obtain composite essential oil microcapsule powder.

4. The use of the plant essential oil intestinal conditioner for ornamental birds of claim 1 in the preparation of a drug for treating intestinal inflammation of ornamental birds.

5. A plant bacteriostatic composition for ornamental birds, characterized by, The plant essential oil intestinal conditioner for ornamental birds of claim 1 and Tween 40.

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