Anti-fatigue composition and preparation method thereof

Abstract

The invention belongs to the technical field of anti-fatigue compositions, particularly relates to an anti-fatigue composition and a preparation method thereof, and provides the following scheme aiming at the problems that an existing anti-fatigue or health-care product is complex in formula, tedious in preparation process and unfavorable for being popularized as a daily medicinal and edible health-care product. The composition is prepared from the following raw materials in parts by weight: 20-40 parts of radix puerariae and 60-80 parts of soybeans, four medicinal and edible raw materials including radix puerariae, soybeans, radix astragali and fructus lycii are selected and scientifically proportioned, an anti-fatigue scheme which is extremely simple in formula and convenient to prepare is formed, the composition has the basic health-care functions of invigorating spleen, replenishing qi, resisting fatigue and the like, and the health-care effects of tonifying spleen, replenishing qi, resisting fatigue and the like are achieved. The product is prepared through simple physical processing, so that the total nutritional ingredients are reserved to the maximum extent, the production cost and the operation difficulty are remarkably reduced, and the health-care food is extremely suitable for being popularized and applied as daily health-care food.

Description

TECHNICAL FIELD

[0001] The present application relates to the technical field of anti-fatigue composition, in particular to an anti-fatigue composition and a preparation method thereof. BACKGROUND

[0002] With the acceleration of life pace, sub-health state is widespread, fatigue, cardiovascular risk, metabolic syndrome and osteoporosis and other problems are increasingly prominent.

[0003] In the prior art, the anti-fatigue or health care product formula is complex, the preparation process is complicated, and it is not conducive to popularization and popularization as a daily health care product of food and medicine homology, therefore, the present application provides an anti-fatigue composition and a preparation method thereof to solve the above problems. SUMMARY

[0004] The present application relates to the technical field of anti-fatigue composition, in particular to an anti-fatigue composition and a preparation method thereof.

[0005] The anti-fatigue composition and the preparation method thereof provided by the present application adopt the following technical scheme:

[0006] An anti-fatigue composition, comprising raw materials, the raw materials comprising the following components in parts by weight: 20-40 parts of radix puerariae, 60-80 parts of soybean, 10-20 parts of radix astragali, and 10-20 parts of medlar.

[0007] Further, the raw materials comprise the following components in parts by weight: 25-35 parts of radix puerariae, 65-75 parts of soybean, 12-18 parts of radix astragali, and 12-18 parts of medlar.

[0008] Further, the raw materials comprise the following components in parts by weight: 30 parts of radix puerariae, 70 parts of soybean, 15 parts of radix astragali, and 15 parts of medlar.

[0009] The present application also provides a preparation method of the anti-fatigue composition, wherein the anti-fatigue composition is the anti-fatigue composition described above, and the preparation method comprises the following steps:

[0010] S1: selecting raw materials and pretreating the raw materials;

[0011] S2: crushing and mixing the pretreated raw materials;

[0012] S3: packaging the mixed raw materials to obtain the composition product.

[0013] Further, in S1, the soybean is washed and roasted until cooked, the roasting temperature is 120-140 DEG C, and the roasting is performed until the aroma is generated.

[0014] Further, in the S1, the roasted soybeans, the kudzu root, the astragalus root and the medlar are dried respectively.

[0015] Further, in the S2, the processed raw materials are collectively pulverized, the pulverized fineness is 80-120 meshes, and the mixture is obtained.

[0016] Further, in the S3, the mixture is directly packaged to obtain the composition product.

[0017] In summary, the present application has at least one of the following beneficial technical effects:

[0018] 1. The present application is composed of four kinds of medicinal and edible raw materials, i.e. kudzu root, soybeans, astragalus root and medlar, which are scientifically proportioned, have the effects of invigorating the spleen and replenishing qi, raising clear and moistening the muscles, and are beneficial to cardiovascular health, can resist fatigue and aging, and assist in regulating blood sugar, blood pressure and blood lipids, and because of containing protein, vitamins and minerals, have a certain effect on controlling weight and osteoporosis;

[0019] 2. The present application can be simply pulverized and mixed to produce the product, which maximally retains the whole nutritional ingredients of the raw materials, has low production cost, simple operation, and is very suitable for daily health food production and promotion.

[0020] The present application selects four kinds of medicinal and edible raw materials, i.e. kudzu root, soybeans, astragalus root and medlar, and scientifically proportioned, forms a set of formula simple and convenient to prepare anti-fatigue scheme, the composition has the functions of invigorating the spleen and replenishing qi, resisting fatigue and other basic health care functions, and has the synergistic effects of regulating cardiovascular, blood sugar and blood lipids and supplementing nutrition, and is made into a product through simple physical processing, which maximally retains the whole nutritional ingredients, significantly reduces the production cost and operation difficulty, and is extremely suitable for daily health food promotion and application. BRIEF DESCRIPTION OF DRAWINGS

[0021] Figure 1 The present application provides a flow chart of a preparation method of an anti-fatigue composition. DETAILED DESCRIPTION

[0022] The technical solutions in the embodiments of the present application will be clearly and completely described below with reference to the drawings in the embodiments of the present application. Obviously, the described embodiments are only a part of the embodiments of the present application, rather than all the embodiments.

[0023] Embodiment one

[0024] Referring to Figure 1 An anti-fatigue composition includes raw materials, and the raw materials include the following components in parts by weight: kudzu root 20 parts, soybeans 60 parts, astragalus root 10 parts, and medlar 10 parts.

[0025] The application further provides a preparation method of the anti-fatigue composition.

[0026] S1: roasting soybeans to be cooked after cleaning, the roasting temperature is 120 DEG C, and the roasted soybeans are dried together with kudzu root, astragalus and medlar;

[0027] S2: co-milling the treated raw materials, the fineness after milling is 80 meshes, and the mixture is uniformly mixed to obtain a mixed powder;

[0028] S3: directly packaging the mixed powder to obtain a composition product.

[0029] Example two

[0030] Reference Figure 1 An anti-fatigue composition comprises raw materials, and the raw materials comprise the following components in parts by weight: 30 parts of kudzu root, 70 parts of soybeans, 15 parts of astragalus and 15 parts of medlar.

[0031] The application further provides a preparation method of the anti-fatigue composition, and the anti-fatigue composition is the anti-fatigue composition.

[0032] S1: roasting soybeans to be cooked after cleaning, the roasting temperature is 130 DEG C, and the roasted soybeans are dried together with kudzu root, astragalus and medlar;

[0033] S2: co-milling the treated raw materials, the fineness after milling is 100 meshes, and the mixture is uniformly mixed to obtain a mixed powder;

[0034] S3: directly packaging the mixed powder to obtain a composition product.

[0035] Example three

[0036] Reference Figure 1 An anti-fatigue composition comprises raw materials, and the raw materials comprise the following components in parts by weight: 40 parts of kudzu root, 80 parts of soybeans, 20 parts of astragalus and 20 parts of medlar.

[0037] The application further provides a preparation method of the anti-fatigue composition, and the anti-fatigue composition is the anti-fatigue composition.

[0038] S1: roasting soybeans to be cooked after cleaning, the roasting temperature is 140 DEG C, and the roasted soybeans are dried together with kudzu root, astragalus and medlar;

[0039] S2: co-milling the treated raw materials, the fineness after milling is 120 meshes, and the mixture is uniformly mixed to obtain a mixed powder;

[0040] S3: The mixed powder is directly packed to obtain a composition product.

[0041] Effect demonstration

[0042] I. Mouse model test detection

[0043] Toxicity detection and anti-fatigue efficacy detection are carried out by using a mouse model, and the specific experimental process is as follows: acute toxicity test: 40 healthy ICR mice are randomly divided into 4 groups, 10 mice in each group, half male and half female, and a blank control group and 3 dose groups (1.0 g / kg, 2.0 g / kg, 4.0 g / kg) are set up. The composition suspension of the application is given by gavage, and the mice are continuously observed for 14 days, and the body weight change, behavior activity and death of the mice are recorded;

[0044] Anti-fatigue efficacy detection: 60 healthy male ICR mice are randomly divided into 4 groups: a normal control group, a fatigue model group, a sample low-dose group (0.5 g / kg) and a sample high-dose group (1.0 g / kg). The mouse fatigue model is established by using the weight-loaded swimming experiment, and after 28 days of continuous gavage administration, the exhaustive swimming time of the mice is measured, and the contents of lactic acid (BLA), urea nitrogen (BUN) and liver glycogen in the serum are detected.

[0045] II. Human test effect test

[0046] Anti-fatigue human test: 150 volunteers meeting the test requirements are selected and randomly divided into 3 groups, 50 people in each group. The volunteers in the three groups continuously take the anti-fatigue compositions prepared in Examples 1, 2 and 3, respectively. The taking period is 30 days. Before and after the test, the scores are evaluated by using the "Fatigue Self-consciousness Questionnaire", and the effective rate (defined as: the ratio of subjects whose total fatigue score after the test is decreased by ≥5 points compared with that before the test) is calculated. The specific results are shown in Table 1:

[0047] Table 1 Anti-fatigue human test effect

[0048] Group Fatigue symptom improvement effective rate (%) Example 1 88.0 Example 2 90.0 Example 3 86.0

[0049] Result analysis

[0050] Acute toxicity test: as shown in Table 2, no abnormal behavior and death of mice in each dose group was observed within 14 days of observation period, and there was no significant difference in body weight gain compared with the control group (P>0.05), indicating that the composition of the application has no toxic side effects on mice;

[0051] Table 2 Results of acute toxicity test of mice

[0052] Group Initial body weight (g) Final body weight (g) Mortality rate (%) Control group 21.5±1.2 36.8±2.1 0 1.0 g / kg group 21.8±1.1 37.2±1.9 0 2.0 g / kg group 21.3±1.3 36.5±2.3 0 4.0 g / kg group 21.6±1.4 36.9±2.0 0

[0053] As can be seen from the data of Examples 1 to 3 and Table 1, the composition provided by the present application has remarkable efficacy in anti-fatigue of human body. In the human body test, the fatigue self-conscious symptoms of most volunteers are effectively improved after taking the composition, and the effective rate is more than 86.0%.

[0054] In summary, through the mouse model test and the human body test, it can be concluded that the composition provided by the present application is safe and non-toxic, and has remarkable anti-fatigue efficacy.

[0055] The above merely describes the preferred embodiments of the present application, but the protection scope of the present application is not limited thereto, and any person skilled in the art can make equivalent replacements or changes according to the technical solution and the inventive concept of the present application within the technical range disclosed by the present application, which should be covered in the protection scope of the present application.

Claims

1. An anti-fatigue composition comprising raw materials, characterized in that: The raw materials include the following components in parts by weight: 20-40 parts of Pueraria, 60-80 parts of soybean, 10-20 parts of Astragalus, and 10-20 parts of Chinese wolfberry.

2. The anti-fatigue composition according to claim 1, characterized in that: The raw materials include the following components in parts by weight: 25-35 parts of Pueraria, 65-75 parts of soybean, 12-18 parts of Astragalus, and 12-18 parts of Chinese wolfberry.

3. The anti-fatigue composition according to claim 2, wherein: The raw materials include the following components in parts by weight: 30 parts of Pueraria, 70 parts of soybean, 15 parts of Astragalus, and 15 parts of Chinese wolfberry.

4. A method of preparing an anti-fatigue composition according to any one of claims 1 to 3, wherein: The method includes the following steps: S1: selecting raw materials and pretreating the raw materials; S2: crushing the pretreated raw materials and mixing them; S3: packaging the mixed raw materials to obtain a composition product.

5. A process for the preparation of an anti-fatigue composition according to claim 4, characterized in that: In S1, the soybean is cleaned and then roasted until cooked at a temperature of 120-140°C until an aroma is produced.

6. A process for the preparation of an anti-fatigue composition according to claim 5, characterized in that: In S1, the roasted soybean is dried together with Pueraria, Astragalus, and Chinese wolfberry.

7. A process for the preparation of an anti-fatigue composition according to claim 6, characterized in that: In S2, the treated raw materials are crushed together to a fineness of 80-120 mesh and then mixed evenly to obtain a mixed powder.

8. A process for the preparation of an anti-fatigue composition according to claim 7, characterized in that: In S3, the mixed powder is directly packaged to obtain a composition product.

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