Degassing fluid coupling system

Abstract

The invention discloses a degassing fluid coupling system which comprises a coupling device and a degassing fluid circulating device, the coupling device comprises a coupling frame and an ultrasonic treatment transducer, and the coupling frame comprises a first frame, a second frame and a coupling film. Water of an external water source is primarily degassed through the degassing mechanism, dissolved gas in the water is removed, then the water flows into the water storage tank to be stored, the degassed water in the water storage tank needs to enter the degassing mechanism again to be deeply degassed, and the treated water can selectively flow back to the water storage tank for standby application or is directly conveyed to the coupling containing cavity through a water conveying pipeline to serve as an acoustic coupling medium. The ultrasonic treatment transducer located in the coupling containing cavity is in stable ultrasonic coupling with the skin of the human body by means of an acoustic coupling medium. The process is completed through a coupling film made of a biocompatible material, the acoustic transmission performance can be maximized through the coupling film, ultrasonic imaging artifacts are remarkably reduced, the acoustic performance is better, and image interference can be further reduced.

Description

Technical Field

[0001] This invention relates to the field of medical device technology, and in particular to a degassing fluid coupling system. Background Technology

[0002] Histotripsy is a novel non-invasive ablation technique. Its core principle is to precisely induce a controlled cavitation effect in the target lesion area using extremely short and intense acoustic pulses. Microbubbles within the target area undergo violent expansion and collapse, mechanically homogenizing the cells and tissue structures within the lesion volume, ultimately achieving lesion removal. This outcome is distinctly different from the coagulative necrosis caused by thermal ablation. To achieve this effect, the acoustic energy must be delivered in the form of high-amplitude pulses with a low duty cycle. With its non-thermal destructive core characteristic, it has become an important innovative direction in the field of ablation technology.

[0003] Compared to traditional ablation techniques such as High-Intensity Focused Ultrasound (HIFU), Histotripsy offers three significant advantages: First, it employs a mechanical rather than thermal tissue destruction process, fundamentally avoiding the risk of damage to surrounding normal tissue caused by heat diffusion; second, the cavitation signal is bright under ultrasound imaging, allowing for direct confirmation of the treatment target and positioning accuracy, thus improving treatment safety; and third, the treated tissue typically exhibits a darker, low-echo characteristic on ultrasound imaging (except in special cases), facilitating real-time assessment of the treatment area. As an important supplement to existing thermal ablation techniques such as microwave, radiofrequency, cryotherapy, and radiation ablation, it achieves precise and controllable damage generation through cavitation mechanisms, without relying on heat, cold, or high-energy radiation, expanding the application scenarios of non-invasive treatment.

[0004] However, existing ablation techniques still have many shortcomings: traditional thermal ablation easily damages normal tissues, radiation ablation carries the risk of whole-body radiation, and most techniques suffer from the problem of unintuitive monitoring of treatment effects. Histotripsy itself is not perfect either; it still suffers from ultrasound imaging artifacts, which interfere with image clarity and thus reduce acoustic transmission performance, potentially affecting treatment precision and the accuracy of effect assessment. This is a key area that needs to be addressed in future technological optimization. The complementary advantages and disadvantages of various techniques provide a basis for personalized selection of clinical ablation treatment plans.

[0005] Therefore, there is an urgent need to propose a degassing fluid coupling system to solve the above problems. Summary of the Invention

[0006] The purpose of this invention is to provide a degassing fluid coupling system that maximizes acoustic transmission performance and reduces ultrasonic imaging artifacts by designing the proportions of a membrane material, and designs the processing of the acoustic coupling medium to improve the working efficiency of the acoustic coupling medium.

[0007] To achieve this objective, the present invention adopts the following technical solution: A degassing fluid coupling system, comprising: A coupling device includes a coupling frame and an ultrasound therapy transducer. The coupling frame includes a first frame, a second frame, and a coupling membrane. The lower edge of the first frame is detachably connected to the upper edge of the second frame. The upper edge of the first frame is configured to contact the skin. The coupling membrane is sandwiched between the first frame and the second frame, and a coupling cavity is formed between the coupling membrane and the first frame. The coupling cavity is filled with an acoustic coupling medium. The coupling membrane is made of a biocompatible material, and the weight of oil in the coupling membrane accounts for 30%-70% of the total weight. At least a portion of the ultrasound therapy transducer is immersed in the acoustic coupling medium. The degassing fluid circulation device includes a moving mechanism, a water storage tank, and a degassing mechanism. The moving mechanism is provided with a first port and a second port. The first port is connected to an external water source. The first connection port of the water storage tank is connected to the first port or the second connection port of the water storage tank through the degassing mechanism. The second port is connected to the coupling cavity through a water supply pipeline.

[0008] Preferably, the degassing fluid circulation device further includes a water filter, the inlet of which is connected to the first port, and the outlet of which is connected to the degassing mechanism.

[0009] Preferably, the degassing fluid circulation device also includes a wastewater tank and a first water pump. The moving mechanism is also provided with a third port. The wastewater tank is connected to the third port through the first water pump, and the third port is connected to the coupling cavity through a water supply pipeline.

[0010] Preferably, the degassing fluid coupling system also includes a support structure, one end of which is connected to the moving mechanism and the other end of which is connected to the coupling frame.

[0011] Preferably, the support structure includes at least three robotic arms connected in sequence.

[0012] Preferably, the degassing fluid coupling system also includes a flow sensor and a display screen. The detection end of the flow sensor is inserted into the coupling cavity, and the flow sensor is electrically connected to the display screen.

[0013] Preferably, the degassing fluid coupling system further includes a controller, and the degassing fluid circulation device further includes a first solenoid valve and a second solenoid valve. The first solenoid valve and the second solenoid valve are respectively connected to the two ends of the degassing mechanism, and the controller is respectively connected to the flow sensor, the first solenoid valve and the second solenoid valve.

[0014] Preferably, the thickness of the coupling film is set to be in the range of 2.0 mm to 4.0 mm, and the tensile strength of the coupling film is greater than 0.4 MPa.

[0015] Preferably, at least one of the first frame, the second frame, and the coupling film is a transparent element.

[0016] Preferably, the coupling frame further includes a connector, the two ends of which are connected to the side surfaces of the first frame and the second frame, respectively.

[0017] The beneficial effects of this invention are: This invention provides a degassing fluid coupling system, including a coupling device and a degassing fluid circulation device. The coupling device includes a coupling frame and an ultrasound therapy transducer. The coupling frame includes a first frame, a second frame, and a coupling membrane. The lower edge of the first frame is detachably connected to the upper edge of the second frame. The upper edge of the first frame is configured to contact the skin. The coupling membrane is sandwiched between the first and second frames, forming a coupling cavity with the first frame. The coupling cavity is filled with an acoustic coupling medium. The coupling membrane is made of a biocompatible material, and the oil content in the coupling membrane accounts for 30%-70% of its total weight. At least a portion of the ultrasound therapy transducer is immersed in the acoustic coupling medium. The degassing fluid circulation device includes a moving mechanism, a water tank, and a degassing mechanism. The moving mechanism has a first port and a second port. The first port is connected to an external water source. The first connection port of the water tank is connected to the first port or the second connection port of the water tank through the degassing mechanism. The second port is connected to the coupling cavity through a water supply pipe. Water from an external source undergoes initial degassing via a degassing mechanism to remove dissolved gases before flowing into a storage tank. The degassed water in the tank then re-enters the degassing mechanism for further degassing. The treated water can either be returned to the storage tank for later use or directly transported via a pipeline to the coupling cavity as an acoustic coupling medium. The ultrasound therapy transducer located within the coupling cavity requires the acoustic coupling medium to achieve stable ultrasound coupling with the human skin. This process is accomplished using a coupling membrane made of biocompatible material. This membrane maximizes acoustic transmission performance and significantly reduces ultrasound imaging artifacts, resulting in superior acoustic performance and further reduced image interference. Furthermore, the degassing fluid circulation device optimizes the acoustic coupling medium processing flow, significantly improving the efficiency of the acoustic coupling medium compared to existing technologies, making the entire processing system more complete and reliable. Attached Figure Description

[0018] Figure 1 This is a schematic diagram of the degassing fluid coupling system provided in this embodiment; Figure 2 This is a schematic diagram of the coupling device provided in this embodiment; Figure 3 This is a schematic diagram of the degassing fluid circulation device provided in this embodiment; Figure 4 This is a schematic diagram of the structure of the ultrasound therapy transducer provided in this embodiment.

[0019] In the picture: 11. Coupling frame; 111. First frame; 112. Second frame; 113. Connector; 12. Ultrasonic therapy transducer; 21. Moving mechanism; 211. First port; 212. Second port; 213. Third port; 22. Water tank; 23. Degassing mechanism; 24. Water filter; 25. Wastewater tank; 26. Controller; 27. Display screen; 281. First solenoid valve; 282. Second solenoid valve; 283. Third solenoid valve; 291. First water pump; 292. Second water pump; 31. Water supply pipeline; 32. Support structure. Detailed Implementation

[0020] The present invention will now be described in further detail with reference to the accompanying drawings and embodiments. It should be understood that the specific embodiments described herein are merely illustrative of the invention and not intended to limit it. Furthermore, it should be noted that, for ease of description, the accompanying drawings show only the parts relevant to the present invention, and not all of the structures.

[0021] In the description of this invention, unless otherwise explicitly specified and limited, the terms "connected," "linked," and "fixed" should be interpreted broadly. For example, they can refer to a fixed connection, a detachable connection, or an integral part; they can refer to a mechanical connection or an electrical connection; they can refer to a direct connection or an indirect connection through an intermediate medium; they can refer to the internal communication of two components or the interaction between two components. Those skilled in the art can understand the specific meaning of the above terms in this invention based on the specific circumstances.

[0022] In this invention, unless otherwise explicitly specified and limited, "above" or "below" the second feature can include direct contact between the first and second features, or contact between the first and second features through another feature between them. Furthermore, "above," "over," and "on top" of the second feature includes the first feature directly above or diagonally above the second feature, or simply indicates that the first feature is at a higher horizontal level than the second feature. "Below," "below," and "under" the second feature includes the first feature directly below or diagonally below the second feature, or simply indicates that the first feature is at a lower horizontal level than the second feature.

[0023] In the description of this embodiment, the terms "upper," "lower," "right," etc., refer to the orientation or positional relationship shown in the accompanying drawings. They are used only for ease of description and simplification of operation, and do not indicate or imply that the device or element referred to must have a specific orientation, or be constructed and operated in a specific orientation. Therefore, they should not be construed as limitations on the present invention. In addition, the terms "first" and "second" are used only for distinction in description and have no special meaning.

[0024] This embodiment provides a degassing fluid coupling system that maximizes acoustic transmission performance and reduces ultrasonic imaging artifacts by designing the proportions of a membrane material, and designs the processing of the acoustic coupling medium to improve its working efficiency.

[0025] Specifically, such as Figures 1 to 4 As shown, a degassing fluid coupling system includes a coupling device and a degassing fluid circulation device. The coupling device includes a coupling frame 11 and an ultrasound therapy transducer 12. The coupling frame 11 includes a first frame 111, a second frame 112, and a coupling membrane. The lower edge of the first frame 111 is detachably connected to the upper edge of the second frame 112. The upper edge of the first frame 111 is configured to contact the skin. The coupling membrane is sandwiched between the first frame 111 and the second frame 112, and a coupling cavity is formed between the coupling membrane and the first frame 111. The coupling cavity is filled with an acoustic coupling medium. The coupling membrane is made of a biocompatible material, and the oil content in the coupling membrane accounts for 30%-70% of the total weight. It should be noted that the coupling membrane typically contains 40%-50% oil, and its specific oil content is not specifically limited in this embodiment. The first frame 111 and the second frame 112 can be modified to various sizes and shapes according to actual needs and to adapt to the patient's needs to ensure good coupling of the ultrasound therapy transducer 12 during treatment. The structure of the coupling frame 11 is usually made by molding, casting, 3D printing, etc. It can be used for single use or reused but needs to be sterilized to ensure that it is sterile each time it is used. Sterilization can be carried out by any known method, including but not limited to ethylene oxide, gamma rays, electron beam, autoclaving, steam, etc.

[0026] The coupling membrane is positioned appropriately between the first frame 111 and the second frame 112, forming a water seal between them and contacting the patient's skin. The coupling membrane uses a biocompatible material to couple the coupling frame 11 and the acoustic coupling medium to the patient's skin. Within the coupling frame 11, an ultrasound therapy transducer 12 or treatment head is placed, for example, positioning the therapy transducer in the desired location and maintaining its posture within the coupling support structure.

[0027] At least a portion of the ultrasound therapy transducer 12 is immersed in the acoustic coupling medium, and the ultrasound therapy transducer 12 is configured to rotate within the coupling cavity to improve skin compatibility. For example... Figure 4 As shown, the core function of the ultrasound therapy transducer 12 is to generate high-intensity focused ultrasound, a technique also known as histotripsy. The ultrasound therapy transducer 12 consists of at least one function generator, a signal amplifier, a therapy transducer body, and a matching power supply module. These components work together to generate, amplify, and convert electrical signals into acoustic energy.

[0028] The degassing fluid circulation device includes a moving mechanism 21, a water storage tank 22, and a degassing mechanism 23. The moving mechanism 21 is provided with a first port 211 and a second port 212. The first port 211 is connected to an external water source. The first connection port of the water storage tank 22 is connected to the first port 211, the second connection port of the water storage tank 22, or the second port 212 through the degassing mechanism 23. The second port 212 is connected to the coupling cavity through a water supply pipeline 31. This device is responsible for delivering the acoustic coupling medium (degassed water) to the coupling cavity to ensure that the water quality meets the specified requirements (including key indicators such as temperature and gas saturation). The device also realizes the replenishment of water to the water storage tank 22 and the discharge of waste liquid through the first port 211 and the second port 212. The device can be moved in various scenarios as needed through the moving mechanism 21 to adapt to clinical use environments such as hospitals and nursing rooms. The degassing mechanism 23 includes a silicone hollow fiber membrane, a vacuum pump, and a degassing membrane, such that when fluid moves through the degassing module, the degassing contactor can partially degas to a fraction of a billionth at a flow rate of approximately 1.5 L / min, and can remove dissolved O2, CO2, and N2 gases from the water. In this embodiment, the water tank 22 contains an acoustic coupling medium (e.g., degassed water) with a volume up to 20 L; in other embodiments, the water tank 22 may have a volume of 30 L.

[0029] Water from an external water source (tap water or bottled water) undergoes preliminary degassing via degassing mechanism 23 to remove dissolved gases before flowing into storage tank 22. The degassed water in storage tank 22 then re-enters degassing mechanism 23 for further degassing. The treated water can be either returned to storage tank 22 for later use or directly transported to coupling cavity via water pipeline 31 as an acoustic coupling medium. The ultrasound therapy transducer 12, located within the coupling cavity, requires the acoustic coupling medium to achieve stable ultrasound coupling with human skin. This process is accomplished using a coupling membrane made of biocompatible material. This membrane maximizes acoustic transmission performance and significantly reduces ultrasound imaging artifacts, resulting in superior acoustic performance and further reduced image interference. Furthermore, the degassing fluid circulation device optimizes the acoustic coupling medium processing flow, significantly improving the efficiency of acoustic coupling medium utilization compared to existing technologies, making the entire processing system more complete and reliable in operation. The closed area achieved through the coupling membrane and the first frame 111 in a patient coupling system for tissue destruction typically has the following functions, including but not limited to: 1) a membrane / barrier membrane required to provide a closed, sealed, and conformal interface between the patient coupling and the tissue destruction system; 2) the first frame 111 providing sufficient working and top space to hold the coupling membrane and provide the range of motion required for the operation of the ultrasound therapy transducer 12; and 3) a coupling cavity containing a sufficient volume of acoustic coupling medium to ensure the acoustic coupling process of the ultrasound therapy transducer 12. It should be noted that, in specific application scenarios, the degassed fluid coupling system can be placed in operating rooms and sterile environments for minimally invasive or non-invasive treatments. Energy is transferred to the lesion through the coupling device to generate acoustic cavitation. Depending on the application scenario, the system can be placed in different positions on the patient as needed, providing sufficient working space for placing the coupling frame 11 to improve the applicability of the degassed fluid coupling system.

[0030] In this embodiment, the ultrasound therapy transducer 12, compared to existing mainstream high-intensity focused ultrasound (HIFU) devices, adopts a multi-element phased array drive architecture. During treatment, it excites the piezoelectric ceramic element with high-amplitude electrical pulses (peak voltage > 2000V), causing it to generate therapeutic ultrasound pulses within microseconds. This induces a cavitation effect in the focal region. Specifically, the impact effect is achieved through a high-amplitude peak negative pressure exceeding the intrinsic cavitation threshold within 1-2 cycles (for water-based soft tissue, the cavitation threshold is typically 24-28MPa). This cavitation effect is triggered by the sound pressure generated during the negative half-cycle of the pulse exceeding the tissue's intrinsic threshold, i.e., the "intrinsic threshold mechanism." During treatment, multiple parameters need to be precisely controlled, including but not limited to ultrasound frequency, pulse number, pulse length, pulse period, pulse repetition frequency, and duty cycle. These parameters can be configured through embedding or combination to adapt to different treatment needs; this is a conventional technique and will not be elaborated upon in this embodiment. In addition, the structural parameters of the ultrasound therapy transducer 12 (including size, shape, focal length, number of array elements, array element distribution and operating frequency, etc.) need to be designed and optimized according to actual needs. In particular, for superficial targets or deep treatment areas such as the liver, the focal length and number of array elements need to be adjusted to adapt to different treatment depths to ensure treatment accuracy.

[0031] It should be noted that the first frame 111 and the second frame 112 are composed of polyurethane, polystyrene copolymer, polyethylene copolymer, polylactic acid (glycolic acid), polyhydroxybutyrate (phosphonazine), polyester, polyethylene glycol, polyethylene oxide, polyacrylamide, polyhydroxyethyl methacrylate, polyalkylene acrylate, polyamide, poly(imino carbonate), polyalkylene acrylate, polyoxyethylene ester, polyorthoester, polyphosphazene and its copolymers, block copolymers, homopolymers, blends, and combinations thereof. The coupling membrane is made of polylactic acid (… The composition consists of several components of the following: glycolic acid, polyhydroxybutyrate (phosphonazine), polyester, polyethylene glycol, polyethylene oxide, polyacrylamide, polybutene, hydrophobic polyester, glycerol, poly(amino acid), copolymer (ether-ester), polyalkylene acrylate, polyamide, poly(imino carbonate), polyalkylene acrylate, polyoxyethylene ester, polyorthoester, polyphosphazene and its copolymers, block copolymers, homopolymers, and blends. The specific material composition of the first frame 111, the second frame 112, and the coupling membrane is not specifically limited in this embodiment and can be adjusted according to the actual situation.

[0032] Furthermore, the coupling membrane has a thickness ranging from 2.0mm to 4.0mm, precisely matching the acoustic impedance of the ultrasound transducer 12 and human skin. This maximizes acoustic energy transmission efficiency, reduces ultrasound imaging artifacts, and ensures both membrane flexibility and structural strength, achieving a tight fit with the skin and ultrasound transducer 12. This avoids the problems of easy breakage due to excessive thinness or attenuation of acoustic energy due to excessive thickness, thus meeting clinical treatment needs. Moreover, the coupling membrane has a tensile strength greater than 0.4MPa, further enhancing its impact and pressure resistance, preventing damage during ultrasound treatment, ensuring stable acoustic energy transmission, and meeting the needs of long-term clinical use. It should be noted that various parameters of the coupling membrane can be optimized, including thickness, overall thickness distribution, density, and formulation (e.g., polymer molecular weight and copolymer ratio, additives, plasticizers, etc.), specifically optimized to maximize acoustic transmission performance and reduce ultrasound imaging artifacts, including but not limited to membrane reflection and refraction.

[0033] Optionally, the degassing fluid circulation device also includes a water filter 24 and a third solenoid valve 283. The inlet of the water filter 24 is connected to the first port 211 through the third solenoid valve 283, and the outlet of the water filter 24 is connected to the first connection port of the degassing mechanism 23. The water filter 24 performs preliminary filtration treatment on the water from the external water source, effectively intercepting suspended solids, particulate impurities and colloids in the water, preventing impurities from entering the degassing mechanism 23 and causing component blockage or operational interference, significantly reducing the workload of the degassing mechanism 23, thereby greatly improving its degassing efficiency and operational stability, and ensuring the smooth progress of subsequent water treatment processes.

[0034] Furthermore, the degassing fluid circulation device also includes a wastewater tank 25 and a first water pump 291. The moving mechanism 21 is also provided with a third port 213. The wastewater tank 25 is connected to the third port 213 through the first water pump 291. The third port 213 is connected to the coupling cavity through the water supply pipeline 31. After the ultrasound treatment process is completed, the first water pump 291 provides stable power, and the used acoustic coupling medium in the coupling cavity is efficiently recycled to the wastewater tank 25 through the third port 213, realizing the centralized collection and subsequent standardized treatment of the acoustic coupling medium, and ensuring a clean and orderly operating environment for the degassing fluid circulation device.

[0035] Optionally, the degassing fluid coupling system also includes a support structure 32. One end of the support structure 32 is connected to the moving mechanism 21, and the other end of the support structure 32 is connected to the coupling frame 11. On the one hand, the rigid connection design with the coupling frame 11 provides a stable and reliable support force for the coupling frame 11, effectively suppressing the vibration and displacement generated by the operation of the equipment during ultrasound treatment, and ensuring the positional accuracy and structural stability of the coupling frame 11. On the other hand, the layout of the support structure 32 is highly consistent with the water supply pipeline 31, which can form a uniform support force on the water supply pipeline 31, avoiding problems such as bending or falling off of the pipeline due to its own weight or external force, and ensuring the continuity and smoothness of the acoustic coupling medium delivery.

[0036] Furthermore, the support structure 32 includes at least three sequentially connected robotic arms, enabling multi-dimensional displacement adjustment of the coupling frame 11, covering horizontal translation, vertical lifting, and angle fine-tuning. This allows for flexible adaptation to the treatment positions and site requirements of different patients, further improving the positioning accuracy of the coupling frame 11, reducing ultrasound coupling deviation, and ensuring the stability and precision of the treatment process. In this embodiment, the number of robotic arms is three; in other embodiments, the number of robotic arms can be four, five, or six, etc.

[0037] Optionally, the degassing fluid coupling system also includes a flow sensor and a display screen 27. The detection end of the flow sensor is inserted into the coupling cavity. Both the flow sensor and the temperature sensor are electrically connected to the display screen 27. The flow sensor collects the volume data of the acoustic coupling medium in the coupling cavity in real time and transmits the data to the equipment control system. The display screen 27 then displays this data in a clear and intuitive digital form in real time, allowing the operator to accurately and conveniently grasp the volume status of the medium in the cavity without additional detection operations, and make timely judgments on replenishment or discharge, ensuring the stable progress of the ultrasound treatment process. It should be noted that the degassing fluid coupling system also includes temperature sensors and pressure sensors for detection, which are all commonly used detection methods in this field and will not be described in detail here.

[0038] Furthermore, the degassing fluid coupling system also includes a controller 26, and the degassing fluid circulation device includes a first solenoid valve 281, a second solenoid valve 282, and a second water pump 292. The first solenoid valve 281 is connected to the second connection port of the water storage tank 22, the first connection port of the degassing mechanism 23, and the second port 212, respectively. The second solenoid valve 282 is connected to the first connection port of the water storage tank 22, the second connection port of the degassing mechanism 23, and the wastewater tank 25, respectively. The controller 26 is connected to the flow sensor, the temperature sensor, the first water pump 291, the second water pump 292, and the first solenoid valve 292, respectively. The first solenoid valve 281 and the second solenoid valve 282 are connected by a signal. The flow sensor monitors the capacity of the acoustic coupling medium in the coupling cavity in real time and feeds the data back to the controller 26. The controller 26 analyzes and judges according to the preset capacity threshold and precisely controls the opening and closing status and different connection paths of the first solenoid valve 281 and the second solenoid valve 282, thereby automatically realizing the on-demand replenishment of degassed water and the orderly discharge of excess acoustic coupling medium, ensuring the stability of the capacity of the acoustic coupling medium in the coupling cavity. The controller 26 can also be used to control all functions of the first pump and the second water pump 292, including but not limited to the pump degassing control device.

[0039] Optionally, at least one of the first frame 111, the second frame 112, and the coupling membrane is transparent. Using a transparent first frame 111 allows visualization of the process of delivering the acoustic coupling medium into the coupling cavity. Using a transparent first frame 111 and a transparent second frame 112 allows visualization of the entire process of delivering the acoustic coupling medium into the coupling cavity, facilitating the operator's direct observation of the flow state and filling effect of the acoustic coupling medium, and timely detection and avoidance of problems such as blockage of the water supply pipe 31 and uneven distribution of the acoustic coupling medium. At the same time, with a transparent or semi-transparent coupling membrane, the contact state changes between the coupling membrane and the human skin can be observed in real time, accurately judging the fit and contact gap, further improving the control over the entire process of ultrasound coupling and ensuring the stability of the treatment.

[0040] Furthermore, the coupling frame 11 also includes a connector 113, which comprises two rotatably connected parts. The two ends of the connector 113 are respectively connected to the side surfaces of the first frame 111 and the second frame 112. By means of the closing and opening actions of the two parts of the connector 113, a stable connection and quick disassembly of the first frame 111 and the second frame 112 can be achieved. When the two parts of the connector 113 are closed, the first frame 111 and the second frame 112 can be precisely locked together, thereby forming a uniform and stable clamping effect on the edge of the coupling membrane. When the two parts of the connector 113 are open, the first frame 111 and the second frame 112 can be easily separated, which facilitates the replacement and maintenance of the coupling membrane and meets the convenience requirements of clinical operation.

[0041] The working process and principle of the degassing fluid circulation device provided in this embodiment are as follows: First Deaeration Cycle: During the water storage process, controller 26 controls the first solenoid valve 281 to connect the outlet of the water filter 24 and the first connection port of the deaeration mechanism 23. Controller 26 also controls the second solenoid valve 282 to connect the second connection port of the deaeration mechanism 23 and the first connection port of the water storage tank 22. Water enters through the first port 211, undergoes preliminary filtration through the water filter 24, and then passes through the first solenoid valve 281 into the deaeration mechanism 23 for deaeration to the first deaeration threshold. The water then flows through the second solenoid valve 282 into the water storage tank 22 for storage of deaerated water. At this time, the deaerated water can selectively maintain the first deaeration threshold.

[0042] II. Second Degassing Cycle: At this time, controller 26 controls the first solenoid valve 281 to connect the second connection port of the water storage tank 22 to the first connection port of the degassing mechanism 23, and controller 26 controls the second solenoid valve 282 to connect the second connection port of the degassing mechanism 23 to the first connection port of the water storage tank 22. The degassed water in the water storage tank 22 is drawn out by the second water pump 292 and flows through the second solenoid valve 282 into the degassing mechanism 23 for a second degassing to the second degassing threshold, and then flows back into the water storage tank 22 through the first solenoid valve 281 to reduce the amount of residual dissolved oxygen.

[0043] Third, the third degassing cycle: Water is added to the coupling device. At this time, the controller 26 controls the first solenoid valve 281 to connect the first connection port of the degassing mechanism 23 to the second port 212, and the controller 26 controls the second solenoid valve 282 to connect the second connection port of the degassing mechanism 23 to the first connection port of the water storage tank 22. The degassed water in the water storage tank 22 is drawn out by the second water pump 292 and flows through the second solenoid valve 282 into the degassing mechanism 23 for further degassing to the third degassing threshold. Then it flows through the first solenoid valve 281 into the second port 212 and is delivered to the coupling cavity by the water supply pipeline 31.

[0044] It should be noted that the degassing fluid circulation device can omit the second water pump 292, relying instead on the water source flow rate (e.g., tap water flow rate) to move the fluid through the water filter 24, delivering water to the degassing mechanism 23 and sending the medium to the water storage tank 22. During use, the acoustic coupling medium (degassed water) that has passed the third degassing threshold is added to the coupling cavity through the second port 212. In this embodiment, the second degassing threshold is lower than the first degassing threshold, and the third degassing threshold is lower than both the second and first degassing thresholds. It has been verified that each degassing cycle can remove approximately 20%-40% of the remaining dissolved oxygen. The first and third degassing cycles remove 20%-40% of the remaining dissolved oxygen. Since the second cycle can run for a longer time than either the first or third cycle, 60%-80% of the remaining dissolved oxygen can be removed during the second cycle, further improving the removal rate of remaining dissolved oxygen.

[0045] Obviously, the above embodiments of the present invention are merely examples for clearly illustrating the present invention, and are not intended to limit the implementation of the present invention. Those skilled in the art will be able to make various obvious changes, readjustments, and substitutions without departing from the scope of protection of the present invention. It is neither necessary nor possible to exhaustively describe all embodiments here. Any modifications, equivalent substitutions, and improvements made within the spirit and principles of the present invention should be included within the scope of protection of the claims of the present invention.

Claims

1. A degassing fluid coupling system, characterized in that, include: The coupling device includes a coupling frame (11) and an ultrasound therapy transducer (12). The coupling frame (11) includes a first frame (111), a second frame (112), and a coupling membrane. The lower edge of the first frame (111) is detachably connected to the upper edge of the second frame (112). The upper edge of the first frame (111) is configured to contact the skin. The coupling membrane is sandwiched between the first frame (111) and the second frame (112), and a coupling cavity is formed between the coupling membrane and the first frame (111). The coupling cavity is filled with an acoustic coupling medium. The coupling membrane is made of a biocompatible material, and the weight of oil in the coupling membrane accounts for 30%-70% of the total weight. At least a portion of the ultrasound therapy transducer (12) is immersed in the acoustic coupling medium. The degassing fluid circulation device includes a moving mechanism (21), a water storage tank (22), and a degassing mechanism (23). The moving mechanism (21) is provided with a first port (211) and a second port (212). The first port (211) is connected to an external water source. The first connection port of the water storage tank (22) is connected to the first port (211) or the second connection port or the second port (212) of the water storage tank (22) through the degassing mechanism (23). The second port (212) is connected to the coupling cavity through a water supply pipeline (31).

2. The degassing fluid coupling system according to claim 1, characterized in that, The degassing fluid circulation device further includes a water filter (24), the inlet of which is connected to the first port (211), and the outlet of which is connected to the degassing mechanism (23).

3. The degassing fluid coupling system according to claim 2, characterized in that, The degassing fluid circulation device also includes a wastewater tank (25) and a first water pump (291). The moving mechanism (21) is also provided with a third port (213). The wastewater tank (25) is connected to the third port (213) through the first water pump (291). The third port (213) is connected to the coupling cavity through the water supply pipeline (31).

4. The degassing fluid coupling system according to claim 1, characterized in that, The degassing fluid coupling system also includes a support structure (32), one end of which is connected to the moving mechanism (21), and the other end of which is connected to the coupling frame (11).

5. The degassing fluid coupling system according to claim 4, characterized in that, The support structure (32) includes at least three robotic arms connected in sequence.

6. The degassing fluid coupling system according to claim 1, characterized in that, The degassing fluid coupling system also includes a flow sensor and a display screen (27). The detection end of the flow sensor is inserted into the coupling cavity, and the flow sensor is electrically connected to the display screen (27).

7. The degassing fluid coupling system according to claim 6, characterized in that, The degassing fluid coupling system further includes a controller (26), and the degassing fluid circulation device further includes a first solenoid valve (281) and a second solenoid valve (282). The first solenoid valve (281) and the second solenoid valve (282) are respectively connected to the two ends of the degassing mechanism (23), and the controller (26) is signal connected to the flow sensor, the first solenoid valve (281) and the second solenoid valve (282) respectively.

8. The degassing fluid coupling system according to any one of claims 1-7, characterized in that, The thickness of the coupling membrane is set to be in the range of 2.0mm-4.0mm, and the tensile strength of the coupling membrane is greater than 0.4MPa.

9. The degassing fluid coupling system according to any one of claims 1-7, characterized in that, At least one of the first frame (111), the second frame (112), and the coupling film is a transparent element.

10. The degassing fluid coupling system according to any one of claims 1-7, characterized in that, The coupling frame (11) further includes a connector (113), the two ends of which are connected to the side surfaces of the first frame (111) and the second frame (112), respectively.

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