Oral cavity sample preservation device

Abstract

The invention relates to the technical field of storage, in particular to an oral cavity sample storage device which comprises a storage tube, a one-way piece, a collection rod, a sealing column and an interaction plate, and a complete technical scheme is formed through optimization of multiple embodiments. During collection, a sample is obtained through the ball head of the collection rod, and after the storage tube is placed, a preservation solution generates impact and suction through the through hole of the interaction plate by shaking, so that the sample is quickly and uniformly dissolved, and long-term soaking of the collection head is avoided. The one-way piece is designed through a buffer groove, a piston and a push rod, so that the preservation liquid is controllably discharged in a dripping mode, and overflow is prevented. The sealing column is matched with a double-horn-mouth and supporting rod structure through a sliding block-sliding groove-limiting groove, rapid positioning and limiting are achieved, sealing is enhanced, the shaking space is reduced, and the dissolving efficiency is improved. The device avoids detection impurity interference, is reliable in sealing and convenient to operate, adapts to various detection scenes and sample requirements, considers sample storage stability and detection accuracy, and greatly improves the pretreatment efficiency.

Description

Technical Field

[0001] This invention relates to the field of storage technology, and in particular to oral sample preservation devices. Background Technology

[0002] In fields such as oral medicine testing, gene sequencing, and disease screening, the quality of oral sample collection and preservation (such as saliva and mucosal cells) directly affects the accuracy of subsequent test results and is a crucial step in ensuring the smooth progress of testing. Currently, most mainstream oral sample preservation devices on the market use storage tubes as the core carrier, paired with collection rods to collect samples. Preservation solutions maintain sample activity and integrity, and these devices are widely used in clinical testing, scientific research experiments, and other scenarios. With the increasing precision of testing technologies, higher requirements are being placed on the performance of sample preservation devices, including sealing, sample detachment efficiency, and controllable release of the preservation solution.

[0003] Existing oral sample preservation devices have many shortcomings in practical use, making it difficult to meet the needs of accurate testing: On the one hand, after collecting the sample, the collection head of the collection rod needs to be immersed in the preservation solution in the storage tube. Long-term immersion can easily cause the material of the collection head to fall off, introducing impurities that interfere with the test results. Moreover, the sample is difficult to dissolve quickly and evenly in the preservation solution, affecting the sample extraction efficiency and uniformity. On the other hand, the drainage structure of the storage tube is simply designed, mostly with a direct opening or ordinary valve control. During drainage, excessive flow of preservation solution and excessive flow rate can easily occur, causing the testing device to overflow. At the same time, the sealing structure has poor sealing performance, which can easily lead to leakage of preservation solution or external contamination. Furthermore, the sealing and limit adjustment are inconvenient, further affecting the stability of sample preservation and testing. Summary of the Invention

[0004] In view of the problems existing in the prior art, the present invention is proposed.

[0005] To solve the above-mentioned technical problems, the present invention provides the following technical solution: an oral sample preservation device, which includes a storage tube, a one-way component disposed at the bottom of the storage tube, a collection rod disposed inside the storage tube, and a collection ball head disposed at one end of the collection rod, a sealing column sleeved on the outer wall of the collection rod, an interactive plate disposed inside the storage tube, and the interactive plate includes a through hole for observing the interactive plate.

[0006] In a preferred embodiment of the oral sample preservation device of the present invention, the unidirectional component includes an isolation plate embedded in the bottom of the storage tube, the isolation plate has a buffer groove inside, the buffer groove is connected to the inside of the storage tube through a first through hole, the buffer groove is connected to the outside through a second through hole, and the buffer groove has a first elastic element and a piston inside.

[0007] In a preferred embodiment of the oral sample preservation device of the present invention, the piston outer wall is provided with a push rod, and the push rod extends to the outside through the second through hole.

[0008] In a preferred embodiment of the oral sample preservation device of the present invention, the outer wall of the collection rod is provided with a first slider, the sealing column is provided with a first movable channel through which the collection rod can pass, the first movable channel is provided with a first sliding groove, and the end of the first sliding groove is connected to a limiting groove.

[0009] In a preferred embodiment of the oral sample preservation device of the present invention, the end of the first slide groove away from the limiting groove is connected to a horn groove, and the first slide groove array has two parts.

[0010] In a preferred embodiment of the oral sample preservation device of the present invention, the sealing column is provided with a first flared opening on the side near the interactive plate, the bottom of the first flared opening is provided with a first annular column, and the outer wall of the first annular column is wrapped with a sealing gasket.

[0011] In a preferred embodiment of the oral sample preservation device of the present invention, the sealing column is provided with a second flared end away from the first flared end, the end face of the second flared end is provided with a second annular column, and the outer wall of the collection rod is fitted with a cover plate.

[0012] As a preferred embodiment of the oral sample preservation device of the present invention, the outer wall of the collection rod is provided with an annular groove, and the annular groove includes a first inclined surface;

[0013] The cover plate has a second movable channel inside, and a support rod that can slide against the inner wall of the annular groove is provided inside the second movable channel. Both ends of the support rod are provided with arc surfaces.

[0014] In a preferred embodiment of the oral sample preservation device of the present invention, the annular groove further includes a first vertical surface, a second inclined surface, and a second vertical surface.

[0015] In a preferred embodiment of the oral sample preservation device of the present invention, the inner wall of the storage tube is provided with an arc-shaped groove.

[0016] The beneficial effects of this invention are:

[0017] This invention utilizes the through-hole structure design of the interactive plate to generate impact and suction when the preservation solution flows. This allows the sample to quickly detach from the collection bulb and dissolve evenly into the preservation solution, while preventing the collection bulb from detaching due to prolonged immersion. The unidirectional component, combined with a buffer tank, a small-section second through-hole, and a piston pusher structure, enables controlled drip-type drainage of the preservation solution, effectively preventing liquid spillage and adapting to various detection devices. Simultaneously, the elastic component drives the piston to reset and seal, enhancing preservation safety. Attached Figure Description

[0018] To more clearly illustrate the technical solutions of the embodiments of the present invention, the drawings used in the following description of the embodiments will be briefly introduced. Obviously, the drawings described below are only some embodiments of the present invention. For those skilled in the art, other drawings can be obtained based on these drawings without creative effort.

[0019] Figure 1 This is a schematic diagram of the overall structure of the present invention;

[0020] Figure 2 This is a schematic cross-sectional view of the overall structure in this invention;

[0021] Figure 3 In this invention Figure 2 Enlarged schematic diagram of the structure of region A in the middle;

[0022] Figure 4 This is a schematic diagram of the internal structure of the storage tube in this invention;

[0023] Figure 5 This is a schematic diagram of the sealing column structure in this invention;

[0024] Figure 6 In this invention Figure 2 Enlarged schematic diagram of the structure of region B in the middle;

[0025] Figure 7 In this invention Figure 6 Enlarged schematic diagram of the structure of region C in the middle;

[0026] Figure 8 In this invention Figure 6 Enlarged schematic diagram of the structure of region D in the middle. Detailed Implementation

[0027] To make the above-mentioned objects, features and advantages of the present invention more apparent and understandable, the specific embodiments of the present invention will be described in detail below with reference to the accompanying drawings.

[0028] Example 1

[0029] Reference Figures 1-8 This is the first embodiment of the present invention, which provides an oral sample preservation device.

[0030] Specifically, the storage tube 1, the one-way component 2 located at the bottom of the storage tube 1, the acquisition rod 3 located inside the storage tube 1, and the acquisition rod 3 having an acquisition ball head 31 at one end, a sealing post 4 sleeved on the outer wall of the acquisition rod 3, and an interactive plate 5 located inside the storage tube 1, and the interactive plate 5 having a through hole 51 for observing the interactive plate 5.

[0031] The storage tube 1 is a plastic tube with an open top. A one-way connector 2 is embedded at the bottom of the storage tube 1. Opening the one-way connector 2 allows the liquid inside the storage tube 1 to flow out through it. A collection rod 3 is placed inside the storage tube 1, and a collection ball head 31 is fixedly installed at the lower end of the collection rod 3. The collection ball head 31 is used to collect samples from inside the oral cavity. Different materials of collection ball heads 31 can be installed according to actual needs. A sealing post 4 is installed on the outer wall of the collection rod 3 to seal the upper opening of the storage tube 1. An interactive plate 5 is fixedly installed at the lower end of the storage tube 1 near the collection ball head 31. The outer wall of the interactive plate 5 is in contact with the inner wall of the storage tube 1, and a through hole 51 penetrates through it. The interactive plate 5 has multiple arrays. The advantage of this design is that after collecting oral samples, they are directly placed into the storage tube 1. Then, the storage tube 1 is shaken, and the preservation solution inside passes through the through hole 51 of the interactive plate 5. As the cross-section of the preservation solution decreases, the flow rate increases, which impacts the collection ball head 31. The preservation solution then adheres to the surface of the collection ball head 31 and falls, carrying away the sample on the surface. This process is repeated several times to ensure that the sample dissolves into the preservation solution. In addition, the interactive plate 5 also has the advantage that the smaller cross-section and increased flow rate of the preservation solution as it passes through the through hole 51 can create suction and a certain stirring effect, so that the sample dissolves evenly in the preservation solution.

[0032] In summary, when the time is right, the sampling rod 3 inside the storage tube 1 is pulled out, and then the sampling bulb 31 is used to collect the sample. The sample is then placed inside the storage tube 1, with the sampling bulb 31 at the top of the interactive plate 5 and the preservation solution at the bottom. The storage tube 1 is then shaken, and the up-and-down flow of the preservation solution carries the sample into the bottom of the interactive plate 5, causing the preservation solution to separate from the sampling bulb 31. This prevents the sampling bulb 31 from being soaked in the preservation solution for a long time, which could cause some material to detach and lead to errors in subsequent testing. The collected sample is then placed on a regular test tube rack for testing. When testing is required, the one-way valve 2 is opened, and the preservation solution is dripped onto the testing device. The testing device can be a common testing plate, testing paper, or a more precise instrument. In this solution, the one-way valve 2 can be used.

[0033] Example 2

[0034] Reference Figures 1-8 This is the second embodiment of the present invention, which differs from the previous embodiment.

[0035] Specifically, the one-way component 2 includes an isolation plate 21 embedded in the bottom of the storage tube 1. The isolation plate 21 has a buffer groove 211 inside. The buffer groove 211 is connected to the inside of the storage tube 1 through a first through hole 212 and to the outside through a second through hole 213. The buffer groove 211 has a first elastic component 22 and a piston 23 inside.

[0036] An isolation plate 21 is fixedly connected to the lower end of the storage tube 1. The isolation plate 21 has an annular space inside, forming a buffer tank 211. The buffer tank 211 is connected to the interior of the storage tube 1 through a first through-hole 212. The preservation liquid inside the storage tube 1 can flow into the buffer tank 211 through the first through-hole 212. The main function of the buffer tank 211 is to provide a buffer for the preservation liquid, preventing a direct water jet from forming when the one-way component 2 is opened, which could cause excessive leakage of the preservation liquid and overwhelm the detection device. Simultaneously, a second through-hole 213 connects the outside to the buffer tank 211. It should be noted that the cross-section of the second through hole 213 is smaller than that of the first through hole 212; the piston 23 is a spherical structure, and the side near the inside of the storage tube 1 is made flat. One end of the first elastic element 22 is fixedly connected to the flat surface of the piston 23, and the other end is fixedly connected to the upper inner wall of the buffer groove 211. The first elastic element 22 is a conical spring. When inspection is required, the piston 23 is pushed inward to open the second through hole 213. Because the cross-section of the second through hole 213 is small and the piston 23 blocks some space above, the preservation liquid will drip out instead of flowing out directly, thus preventing the preservation liquid from flowing out directly.

[0037] Preferably, the piston 23 has a push rod 231 on its outer wall, and the push rod 231 extends to the outside through the second through hole 213.

[0038] A push rod 231 is fixedly connected to the lower surface of the piston 23. The push rod 231 pushes the piston 23 to move a certain distance into the storage tube 1, opening the second through hole 213, so that the storage liquid drips out.

[0039] In summary, when testing is required, hold the storage tube 1 and place its bottom against the surface of the testing device. The surface of the testing device will then contact the push rod 231, opening the second through hole 213, and the storage liquid will then fall onto the testing device.

[0040] Example 3

[0041] Reference Figures 1-8 This is the third embodiment of the present invention, which is implemented based on the previous embodiment.

[0042] Specifically, the outer wall of the collection rod 3 is provided with a first slider 32, and the sealing column 4 is provided with a first movable channel 41 through which the collection rod 3 can pass. The first movable channel 41 is provided with a first sliding groove 411 inside, and the end of the first sliding groove 411 is connected to a limiting groove 412.

[0043] The first slider 32 is fixedly connected to the collection rod 3 near the collection ball head 31. The first movable channel 41 passes through the sealing column 4, and a vertical first groove 411 is provided on the inner wall of the first movable channel 41. A horizontal limiting groove 412 is connected to the end of the first groove 411, and the first groove 411 and the limiting groove 412 are perpendicular to each other. The advantage of this design is that the sealing column 4 is slidably installed on the outer surface of the collection rod 3. After the sample is collected, the sealing column 4 can be pushed to slide along the surface of the collection rod 3. Then the first slider 32 on the outer wall of the collection rod 3 slides along the first groove 411. When it slides into the end, the sealing column 4 is rotated, so that the first slider 32 enters the limiting groove 412, restricting the sliding of the sealing column 4. Then it is pushed into the storage tube 1, so that the sealing column 4 is close to the interaction plate 5, which reduces the internal space of the storage tube 1. Then the internal preservation liquid is shaken. When the preservation liquid is shaken, the space for the internal preservation liquid to shake back and forth is reduced, the time is shortened, and it is easier to remove the sample from the surface of the collection ball head 31. At the same time, shaking will shorten the dissolution time and improve uniformity.

[0044] Preferably, the end of the first slide groove 411 away from the limiting groove 412 is connected to a horn groove 413, and two arrays of the first slide groove 411 are provided.

[0045] In this design, an outwardly opening horn groove 413 is connected to one end of the first slide groove 411 near the first slider 32. Two first slide grooves 411 are symmetrically arranged, and the two horn grooves 413 are interconnected. When the first slider 32 slides along the horn groove 413, it will slide into the interior of the first slide groove 411. That is, no matter what position or angle the sealing column 4 rotates to, the first slider 32 will slide along the inner wall of the horn groove 413, then slide into the interior of the first slide groove 411, and finally enter the interior of the limiting groove 412, thereby restricting the movement of the sealing column 4.

[0046] Preferably, the sealing post 4 is provided with a first flared opening 42 on the side near the interactive plate 5, and a first annular post 421 is provided at the bottom of the first flared opening 42. The outer wall of the first annular post 421 is wrapped with a sealing gasket 6.

[0047] In this scheme, the outer wall of the sealing column 4 no longer adheres to the inner wall of the storage tube 1. At the same time, the lower end of the sealing column 4 has an outwardly opening first flared mouth 42. The first flared mouth 42 is made of a feasible variable material, such as silicone. A sealing gasket 6 is fixedly installed at the lower end of the first flared mouth 42, so that a fan-shaped space is formed below. After the collection is completed, the sealing column 4 is moved downward and then its movement is restricted by the first slider 32. During this process, the sealing gasket 6 will adhere to the upper surface of the interactive plate 5, thereby squeezing the upper surface of the interactive plate 5 and separating the space above and below the first flared mouth 42.

[0048] The sealing column 4 has a second horn 43 at one end away from the first horn 42, and a second annular column 431 is provided on the end face of the second horn 43. The outer wall of the collection rod 3 is fitted with a cover plate 7.

[0049] The design incorporates a second flared opening 43 fixed at the upper end of the sealing column 4, made of hard plastic. Above the second flared opening 43 is a ring-shaped second ring column 431, made of a deformable material. A cover plate 7 is slidably mounted on the outer surface of the collection rod 3, with rounded corners at the bottom. This design allows the sealing column 4 to slide upwards during production, enabling the cover plate 7 to slide into the second ring column 431, causing it to expand slightly outwards and then press against the storage tube 1. This, combined with the inner wall of the storage tube 1, seals the storage tube 1. During use, a ring-shaped handle 34 is fixedly mounted at the upper end of the collection rod 3. Rotating the handle 34 and applying outward force allows the collection rod 3 to be pulled out. A V-shaped space 44 is formed between the two flared openings, allowing the collection rod 3 to be held within this space during oral sample collection.

[0050] The outer wall of the collecting rod 3 is provided with an annular groove 33, and the annular groove 33 includes a first inclined surface 331;

[0051] The cover plate 7 has a second movable channel 71 inside, and a support rod 8 that can abut against the inner wall of the annular groove 33 is slidably arranged inside the second movable channel 71. Both ends of the support rod 8 are provided with arc surfaces 81.

[0052] The acquisition rod 3 has an annular groove 33 on its outer wall, and the annular groove 33 has a first inclined surface 331. At the same time, the cover plate 7 has multiple second movable channels 71 arranged in an array inside, and a support rod 8 is slidably installed inside the second movable channel 71. Both ends of the support rod 8 are rounded to form an arc surface 81. One end of the support rod 8 can extend into the annular groove 33, and the other end can move out of the second movable channel 71. During production and assembly, the cover plate 7 slides into the second annular column 431, and then the second annular column 431 fits against the inner wall of the storage tube 1. During use, after acquisition, the sealing column 4 slides down, and then the acquisition rod 3 is pressed down. The advantage of this process is that it squeezes the sealing gasket 6 at the lower end of the first horn 42 to fit more closely to the surface of the interactive plate 5. Then, the support rod 8 can be pushed outward to abut against the inner wall of the storage tube 1.

[0053] Preferably, the annular groove 33 further includes a first vertical surface 332, a second inclined surface 333, and a second vertical surface 334.

[0054] The first inclined surface 331 of the annular groove 33 is connected to a vertical first surface 332 at its lower end. The second inclined surface 332 is connected to a second inclined surface 333 at its lower end. The second inclined surface 333 is connected to a second vertical surface 334 at its lower end. During installation, the cover plate 7 is attached to the inner wall of the second annular column 431. The friction force directly restricts the movement of the cover plate 7. The collecting rod 3 moves downward, causing one end of the support rod 8 to move from the surface of the second vertical surface 334 and enter the first vertical surface 332 along the second inclined surface 333. Then, the other end of the support rod 8 presses against the second annular column 431, increasing the friction force and ensuring the sealing.

[0055] The inner wall of the storage tube 1 is provided with an arc-shaped groove 11.

[0056] In this design, an arc-shaped groove 111 is formed by a downward indentation at the upper end of the storage tube 1. After data collection, the user holds the cover plate 7 and presses down on the collection rod 3, causing one end of the support rod 8 to slide from the first vertical surface 332 along the first inclined surface 331 into the outer surface of the collection rod 3. Subsequently, the other end of the support rod 8 enters the interior of the arc-shaped surface 111 along the inner wall of the arc-shaped surface 111, forming a locking connection. Figure 8 The bottom of the arc-shaped groove 11 is more recessed than the top, which is used to snap the support rod 8.

[0057] It should be noted that the above embodiments are only used to illustrate the technical solutions of the present invention and are not intended to limit it. Although the present invention has been described in detail with reference to preferred embodiments, those skilled in the art should understand that modifications or equivalent substitutions can be made to the technical solutions of the present invention without departing from the spirit and scope of the technical solutions of the present invention, and all such modifications or substitutions should be covered within the scope of the claims of the present invention.

Claims

1. An oral sample preservation device, characterized in that: It includes a storage tube (1), a one-way component (2) located at the bottom of the storage tube (1), a collection rod (3) located inside the storage tube (1), and a collection ball head (31) at one end of the collection rod (3), a sealing column (4) sleeved on the outer wall of the collection rod (3), and an interactive plate (5) located inside the storage tube (1), and the interactive plate (5) includes a through hole (51) for observing the interactive plate (5).

2. The oral sample preservation device as described in claim 1, characterized in that: The one-way component (2) includes an isolation plate (21) embedded in the bottom of the storage tube (1). The isolation plate (21) has a buffer groove (211) inside. The buffer groove (211) is connected to the inside of the storage tube (1) through a first through hole (212). The buffer groove (211) is connected to the outside through a second through hole (213). The buffer groove (211) has a first elastic element (22) and a piston (23) inside.

3. The oral sample preservation device as described in claim 2, characterized in that: The piston (23) has a push rod (231) on its outer wall, and the push rod (231) extends to the outside through the second through hole (213).

4. The oral sample preservation device as described in claim 3, characterized in that: The outer wall of the collecting rod (3) is provided with a first slider (32), and the sealing column (4) is provided with a first movable channel (41) through which the collecting rod (3) can pass. The first movable channel (41) is provided with a first sliding groove (411) inside, and the end of the first sliding groove (411) is connected to a limiting groove (412).

5. The oral sample preservation device as described in claim 1 or 4, characterized in that: The end of the first slide groove (411) away from the limiting groove (412) is connected to the horn groove (413), and there are two arrays of the first slide groove (411).

6. The oral sample preservation device as described in claim 5, characterized in that: The sealing column (4) has a first horn (42) on the side near the interactive plate (5), and a first ring column (421) is provided at the bottom of the first horn (42). The outer wall of the first ring column (421) is wrapped with a sealing gasket (6).

7. The oral sample preservation device as described in claim 6, characterized in that: The sealing column (4) has a second horn (43) at one end away from the first horn (42), and a second ring column (431) is provided on the end face of the second horn (43). The outer wall of the collection rod (3) is fitted with a cover plate (7).

8. The oral sample preservation device as described in claim 7, characterized in that: The outer wall of the collecting rod (3) is provided with an annular groove (33), and the annular groove (33) includes a first inclined surface (331); The cover plate (7) has a second movable channel (71) inside, and a support rod (8) that can abut against the inner wall of the annular groove (33) is slidably provided inside the second movable channel (71). Both ends of the support rod (8) are provided with arc surfaces (81).

9. The oral sample preservation device as described in claim 8, characterized in that: The annular groove (33) also includes a first vertical surface (332), a second inclined surface (333), and a second vertical surface (334).

10. The oral sample preservation device as described in claim 9, characterized in that: The inner wall of the storage tube (1) is provided with an arc-shaped groove (11).

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