Micro-lipid calcium supplement carrier

Abstract

The invention provides a micro-fat calcium supplement carrier, which is prepared from the following raw materials in parts by weight: 30 to 35 parts of standard index calcium, 1 to 5 parts of chondroitin, 1 to 5 parts of glucosamine, 8 to 12 parts of pure camel milk, 0.7 part of vitamin D, 2 to 70.3 parts of vitamin K, 1 to 3 parts of phospholipid complex and 8 to 10 parts of excipient. According to the invention, standard calcium, chondroitin, glucosamine, pure camel milk, vitamin D, vitamin K2-7, a phospholipid complex and an excipient are organically mixed by adopting a liposome carrier technology, so that the digestion and absorption of calcium in a body and the distribution of calcium in a specific region are effectively improved, and further the effects of rapid bone growth, increase of bone length (promotion of height increase) and increase of bone density are achieved; the health-care food has the health-care functions of reducing the fracture probability, preventing tooth decay, reducing the death rate of cardiovascular diseases and the like, so that the calcium absorption rate is remarkably improved and reaches up to 95%.

Description

Technical Field

[0001] This invention belongs to the field of traditional Chinese medicine component technology, and in particular relates to a micro-lipid calcium supplement carrier. Background Technology

[0002] Calcium helps reduce the excitability of nerve cells, acting as a natural sedative. Calcium deficiency can lead to neurogenic migraines (affecting 10%-20% of women), irritability, insomnia; in infants, it can cause night terrors, night crying, and night sweats; and in children, it can induce ADHD. Calcium also strengthens the conduction function of the nervous system; simultaneously, calcium helps in the production and release of neurotransmitters, maintaining normal muscle and nerve excitability. High blood calcium levels can inhibit muscle and nerve excitability; when blood calcium is low, neuromuscular excitability increases, leading to convulsions. Calcium deficiency is also a significant cause of irritable bowel syndrome and dysmenorrhea in girls. Calcium affects the permeability of cells and capillaries; calcium deficiency can easily lead to skin allergies, edema, and other symptoms. Calcium also promotes the activity of various enzymes in the body; when calcium is deficient, the secretory function of glandular cells weakens. Calcium is also an enzyme activator, maintaining acid-base balance and participating in the blood clotting process. Blood clotting is a complex process, and one important step is prothrombin, which is an active form of thrombin that requires calcium for activation. In short, calcium is an indispensable trace element for the human body; it is both a constructor and a regulator of the body, and is the source of life.

[0003] However, due to differences in manufacturing processes and formulation techniques, commercially available products currently have lower calcium content (below 40%) and lower absorption rates (below 35%), making them less convenient for the human body to digest and absorb quickly, resulting in poorer health benefits for calcium-containing products. Summary of the Invention

[0004] In view of this, the present invention aims to propose a liposome calcium supplement carrier, which uses liposome carrier technology to effectively improve the absorption and utilization rate of calcium.

[0005] To achieve the above objectives, the technical solution of the present invention is implemented as follows:

[0006] A micro-lipid calcium supplement carrier, wherein the raw materials of the micro-lipid calcium supplement carrier are made from the following parts by weight: 30-35 parts of standard calcium, 1-5 parts of chondroitin, 1-5 parts of glucosamine, 8-12 parts of pure camel milk, 0.7 parts of vitamin D, 0.3 parts of vitamin K2-7, 1-3 parts of phospholipid complex, and 8-10 parts of excipients.

[0007] Furthermore, chondroitin can deliver essential oxygen and nutrients to the joints and help remove waste products from within them. It is crucial to take chondroitin concurrently with glucosamine, as chondroitin promotes the penetration of glucosamine into the joints. Multiple studies, including one published in the New England Journal of Medicine, have shown that combining glucosamine and chondroitin intake can more effectively protect, reverse damage, and promote the repair of articular cartilage. Glucosamine has therapeutic, antioxidant, and anti-aging effects. Pure camel milk is rich in vitamin C and also contains a large amount of unsaturated fatty acids, iron, and vitamin B, all essential for the human body. It is warm in nature, sweet and cold in taste, and non-toxic, possessing the effects of tonifying the middle energizer, replenishing qi, and strengthening muscles and bones.

[0008] Furthermore, the vitamin D is a cyclopentane-polyhydrophenanthrene compound, whose main functions are to promote the absorption of calcium and phosphorus by small intestinal mucosal cells, promote the renewal of calcium salts and new bone formation, promote the reabsorption of calcium and phosphorus by renal tubular cells, promote skin cell growth, and regulate immune function. Vitamin D deficiency can lead to rickets and osteomalacia. The vitamin K2-7 is a type of vitamin K2, that is, vitamin K2 contains 7 isoprene units on its side chain. It is a fat-soluble vitamin and one of the essential vitamins for the human body. The phospholipid complex is a relatively stable compound or complex formed by the drug and phospholipid molecules through charge migration. It can change the physicochemical properties of the parent drug and improve bioavailability. The excipient is an additive in pharmaceutical preparations other than the main drug, also known as an excipient, which mainly functions as an antioxidant and emulsifier in the drug.

[0009] Furthermore, the raw materials of this micro-lipid calcium supplement carrier are made from the following parts by weight: 30-34 parts of standard calcium, 2-5 parts of chondroitin, 1-4 parts of glucosamine, 8-11 parts of pure camel milk, 0.7 parts of vitamin D, 2-70.3 parts of vitamin K, 1-2.5 parts of phospholipid complex, and 8-9.5 parts of excipients.

[0010] Furthermore, the raw materials of this micro-lipid calcium supplement carrier are made from the following parts by weight: 32-34 parts of standard calcium, 3-5 parts of chondroitin, 2-4 parts of glucosamine, 9-11 parts of pure camel milk, 0.7 parts of vitamin D, 0.3 parts of vitamin K2-7, 1-2 parts of phospholipid complex, and 9-9.5 parts of excipients.

[0011] Furthermore, the raw materials of this micro-lipid calcium supplement carrier are preferably made from the following parts by weight: 32 parts of standard calcium, 3 parts of chondroitin, 3 parts of glucosamine, 10 parts of pure camel milk, 0.7 parts of vitamin D, 0.3 parts of vitamin K2-7, 2 parts of phospholipid complex, and 9 parts of excipients.

[0012] Furthermore, the preparation method of the micro-liposome calcium supplement carrier includes the following steps:

[0013] Step (1): Take the indicated calcium, chondroitin, glucosamine, pure camel milk, vitamin D, vitamin K2-7, phospholipid complex and excipients according to the preferred ratio and set aside;

[0014] Step (2): Add the raw materials to the emulsification equipment for emulsification, and strictly control the temperature and time of emulsification;

[0015] Step (3) involves filling and packaging the emulsified drug to achieve the preparation of the micro-lipid calcium supplement carrier.

[0016] Furthermore, in step (1), different medicine containers should be used when taking each raw material, and the raw materials should be stored separately after taking them. This can effectively avoid the mutual mixing of raw materials when taking them and ensure the purity of each raw material.

[0017] Furthermore, in step (2), emulsification is mainly achieved using an ultrasonic emulsifier.

[0018] Furthermore, the emulsification time in step (2) is 60-100 min and the emulsification temperature is 80-85℃. By strictly controlling the emulsification time and temperature, the final processing quality of the micro-lipid calcium supplement carrier is improved.

[0019] Furthermore, in step (3), a measuring cup is required after the finished drug is filled, which makes it convenient for users to take the drug.

[0020] Furthermore, the specifications of this micro-liposome calcium supplement carrier are: 500mg per tablet, and the method of consumption is: 2-4 tablets twice a day, after meals or before bedtime, taken with warm water.

[0021] Compared with existing technologies, the micro-lipid calcium supplement carrier described in this invention has the following advantages:

[0022] This invention employs lipocarrier technology to organically mix calcium, chondroitin, glucosamine, pure camel milk, vitamin D, vitamin K2-7, phospholipid complex, and excipients. This effectively increases the digestion and absorption of calcium in the body and its distribution in specific areas, thereby achieving health benefits such as rapid bone growth, increased bone length (promoting height growth), increased bone density, reduced fracture risk, prevention of tooth decay, and reduced cardiovascular disease mortality. As a result, the calcium absorption rate is significantly improved, reaching up to 95%. Detailed Implementation

[0023] Unless otherwise defined, the technical terms used in the following embodiments have the same meaning as commonly understood by those skilled in the art to which this invention pertains.

[0024] The present invention will now be described in detail.

[0025] A micro-lipid calcium supplement carrier, wherein the raw materials of the micro-lipid calcium supplement carrier are made from the following parts by weight: 30-35 parts of standard calcium, 1-5 parts of chondroitin, 1-5 parts of glucosamine, 8-12 parts of pure camel milk, 0.7 parts of vitamin D, 0.3 parts of vitamin K2-7, 1-3 parts of phospholipid complex, and 8-10 parts of excipients.

[0026] In this embodiment, the chondroitin can deliver essential oxygen and nutrients to the joints and help remove waste products from the joints. It is crucial to take chondroitin concurrently with glucosamine, as chondroitin promotes the penetration of glucosamine into the joints. Multiple studies, including one published in the New England Journal of Medicine, have shown that combining glucosamine and chondroitin intake can more effectively protect, reverse damage, and promote the repair of articular cartilage. Glucosamine has therapeutic, antioxidant, and anti-aging effects. The pure camel milk is rich in vitamin C and also contains a large amount of unsaturated fatty acids, iron, and vitamin B, all essential for the human body. It is warm in nature, sweet and cold in taste, and non-toxic, possessing the effects of tonifying the middle energizer, replenishing qi, and strengthening muscles and bones.

[0027] In this embodiment, the vitamin D is a cyclopentane-polyhydrophenanthrene compound, whose main functions are to promote the absorption of calcium and phosphorus by small intestinal mucosal cells, promote the renewal of calcium salts and new bone formation, promote the reabsorption of calcium and phosphorus by renal tubular cells, promote skin cell growth, and regulate immune function. Vitamin D deficiency can lead to rickets and osteomalacia. The vitamin K2-7 is a type of vitamin K2, that is, vitamin K2 contains 7 isoprene units on its side chain. It is a fat-soluble vitamin and one of the essential vitamins for the human body. The phospholipid complex is a relatively stable compound or complex formed by the drug and phospholipid molecules through charge migration. It can change the physicochemical properties of the parent drug and improve bioavailability. The excipient is an additive in the pharmaceutical preparation other than the main drug, also known as an excipient, which mainly acts as an antioxidant and emulsifier in the drug.

[0028] In this embodiment, the raw materials of the micro-lipid calcium supplement carrier are made from the following parts by weight: 30-34 parts of standard calcium, 2-5 parts of chondroitin, 1-4 parts of glucosamine, 8-11 parts of pure camel milk, 0.7 parts of vitamin D, 2-70.3 parts of vitamin K, 1-2.5 parts of phospholipid complex, and 8-9.5 parts of excipients.

[0029] In this embodiment, the raw materials of the micro-lipid calcium supplement carrier are made from the following parts by weight: 32-34 parts of standard calcium, 3-5 parts of chondroitin, 2-4 parts of glucosamine, 9-11 parts of pure camel milk, 0.7 parts of vitamin D, 2-70.3 parts of vitamin K, 1-2 parts of phospholipid complex, and 9-9.5 parts of excipients.

[0030] In this embodiment, the raw materials of the micro-lipid calcium supplement carrier are preferably made from the following parts by weight: 32 parts of standard calcium, 3 parts of chondroitin, 3 parts of glucosamine, 10 parts of pure camel milk, 0.7 parts of vitamin D, 0.3 parts of vitamin K2-7, 2 parts of phospholipid complex, and 9 parts of excipients.

[0031] In this embodiment, the preparation method of the liposome calcium supplement carrier includes the following steps:

[0032] Step (1): Take the indicated calcium, chondroitin, glucosamine, pure camel milk, vitamin D, vitamin K2-7, phospholipid complex and excipients according to the preferred ratio and set aside;

[0033] Step (2): Add the raw materials to the emulsification equipment for emulsification, and strictly control the temperature and time of emulsification;

[0034] Step (3) involves filling and packaging the emulsified drug to achieve the preparation of the micro-lipid calcium supplement carrier.

[0035] In this embodiment, in step (1), different medicine containers should be used when taking each raw material, and the raw materials should be stored separately after taking them. This can effectively avoid the mutual mixing of raw materials when taking them and ensure the purity of each raw material.

[0036] In this embodiment, the emulsification in step (2) is mainly achieved by using an ultrasonic emulsifier.

[0037] In this embodiment, the emulsification time in step (2) is 60-100 min and the emulsification temperature is 80-85℃. By strictly controlling the emulsification time and temperature, the final processing quality of the micro-lipid calcium supplement carrier is improved.

[0038] In this embodiment, a measuring cup is required after the finished drug is filled in step (3) to facilitate the user's consumption.

[0039] In this embodiment, the specifications of the micro-lipid calcium supplement carrier are: 500mg per tablet, and the method of consumption is: 2-4 tablets twice a day, after meals or before bedtime, taken with warm water.

[0040] The above description is only a preferred embodiment of the present invention and is not intended to limit the present invention. Any modifications, equivalent substitutions, improvements, etc., made within the spirit and principles of the present invention should be included within the protection scope of the present invention.

Claims

1. A micro-liposomal calcium supplement carrier, characterized by: The raw materials of the micro-lipid calcium supplement carrier are prepared according to the weight ratio of the following raw materials: 30-35 parts of marker calcium, 1-5 parts of chondroitin, 1-5 parts of glucosamine, 8-12 parts of pure camel milk, 0.7 parts of vitamin D, 0.3 parts of vitamin K2-7, 1-3 parts of phospholipid complex, and 8-10 parts of excipient.

2. The microemulsified calcium supplement carrier according to claim 1, wherein: The raw materials of the micro-lipid calcium supplement carrier are prepared according to the weight ratio of the following raw materials: 30-34 parts of marker calcium, 2-5 parts of chondroitin, 1-4 parts of glucosamine, 8-11 parts of pure camel milk, 0.7 parts of vitamin D, 0.3 parts of vitamin K2-7, 1-2.5 parts of phospholipid complex, and 8-9.5 parts of excipient.

3. The microemulsified calcium supplement carrier of claim 1, wherein: The raw materials of the micro-lipid calcium supplement carrier are prepared according to the weight ratio of the following raw materials: 32-34 parts of marker calcium, 3-5 parts of chondroitin, 2-4 parts of glucosamine, 9-11 parts of pure camel milk, 0.7 parts of vitamin D, 0.3 parts of vitamin K2-7, 1-2 parts of phospholipid complex, and 9-9.5 parts of excipient.

4. The microemulsified calcium supplement carrier of claim 1, wherein: The raw materials of the micro-lipid calcium supplement carrier are prepared according to the weight ratio of the following raw materials: 32-34 parts of marker calcium, 3-5 parts of chondroitin, 2-4 parts of glucosamine, 9-11 parts of pure camel milk, 0.7 parts of vitamin D, 0.3 parts of vitamin K2-7, 1-2 parts of phospholipid complex, and 9-9.5 parts of excipient.

5. A method of preparing a micro- liposomal calcium supplement carrier as claimed in any one of claims 1 to 4, characterized by: The method comprises the following steps: Step (1): according to the preferred ratio, marker calcium, chondroitin, glucosamine, pure camel milk, vitamin D, vitamin K2-7, phospholipid complex, and excipient are taken respectively and prepared; Step (2): the raw materials are added to the emulsification equipment for emulsification processing, and the temperature and time of emulsification are strictly controlled; Step (3): the emulsified medicine is filled and packaged to realize the preparation of the micro-lipid calcium supplement carrier.

6. The method for preparing a micro-lipid calcium supplement carrier according to claim 5, characterized in that: In step (1), different containers are used to take the raw materials, and the taken raw materials are stored separately.

7. The method for preparing a micro-lipid calcium supplement carrier according to claim 5, characterized in that: In step (2), ultrasonic emulsifier is used for emulsification.

8. The method for preparing a micro-lipid calcium supplement carrier according to claim 5, characterized in that: The emulsification time in step (2) is 60-100 minutes, and the emulsification temperature is 80-85°C.

9. The method for preparing a micro-lipid calcium supplement carrier according to claim 5, characterized in that: In step (3), a measuring cup is needed for filling the finished medicine.

10. The method for preparing a micro-lipid calcium supplement carrier according to claim 5, characterized in that: The specification of the micro-lipid calcium supplement carrier is 500 mg per tablet, and the eating method is 2-4 tablets twice a day, after meals or before sleep, and warm water is used for taking.