Freezing and thawing bag protection assembly and freezing and thawing bag protection system

Abstract

The invention provides a freeze-thaw bag protection assembly and a freeze-thaw bag protection system.The freeze-thaw bag protection assembly comprises a protection shell and a bearing piece, the protection shell and the bearing piece are matched to form a containing cavity for containing a freeze-thaw bag, and the outer surface, away from the containing cavity, of the protection shell and / or the bearing piece is provided with a containing groove; the pipe component is used for accommodating a part of the pipe component; and a communication part is arranged between the containing cavity and the containing groove, so that the free end of the pipe assembly can extend to the containing groove through the communication part and be stored, and the freezing and thawing bag has the advantages that the pipe assembly can be stored conveniently, and meanwhile the whole carrying formed by the protection assembly, the freezing and thawing bag and the pipe assembly is not affected.

Description

Technical Field

[0001] This invention relates to the field of biological liquid storage and transportation, and in particular to a freeze-thaw bag protection component and freeze-thaw bag protection system. Background Technology

[0002] In biopharmaceutical processes, to maintain the sterility of biological feedstocks such as antibodies and cells, these feedstocks are typically stored in disposable containers. Existing disposable containers are usually biological feedstock bags made of flexible or elastic materials, and these bags are usually connected to external tubing to allow the biological feedstock to enter and exit the bag. However, because the deformation and abrasion resistance of biological feedstock bags made of flexible or elastic materials are generally limited, the bags are easily damaged during storage, transportation, or refrigeration due to factors such as vibration, abrasion, impact, internal pressure changes, and improper handling, thus compromising the integrity of the bag.

[0003] To protect the integrity of the biological liquid bag during the freezing process, current production methods involve placing the biological liquid bag inside a shell for protection, thereby preserving the integrity of the biological liquid bag and the effectiveness of the biological liquid inside. In subsequent use, the shell containing the bag is placed in a flat environment such as a specialized medical freezer or receiving rack.

[0004] To facilitate the filling of biological feed solutions into or the transfer of biological feed solutions from biological feed solutions bags, the free ends of the tubing connected to the biological feed solutions bags typically extend beyond the housing. This avoids the risk of contamination that would arise from frequently opening the housing when the tubing assembly is completely enclosed. Furthermore, the extension of the freeze-thaw bag tubing beyond the protective housing to a certain length meets the requirements of biopharmaceutical processes (such as sampling and connecting to external equipment).

[0005] However, the tubing extending beyond the shell still needs to be stored outside the shell to facilitate the handling and storage of the bio-liquid bags, tubing, and shell. If the tubing is stored using an external storage structure (such as a storage block with a storage groove), to avoid compromising the connection stability between the bio-liquid bags and tubing, and to facilitate overall handling, the external storage structure needs to be connected to the shell. This setup would damage the shell structure, affecting its structural strength. Furthermore, it would increase the overall size of the structure formed by the external storage structure, shell, bio-liquid bags, and tubing, making transportation and handling difficult. If excessively long tubing is installed around the shell, it increases the complexity and processing difficulty of the surrounding structure, further enlarging the overall shell area and causing difficulties in handling and storage. Moreover, it is difficult to match specific storage spaces on the shell for tubing of different lengths, requiring customized designs for different shell perimeter structures, increasing design complexity and processing costs. Summary of the Invention

[0006] The technical problem to be solved by the present invention is to overcome the defects in the prior art, thereby providing a freeze-thaw bag protection component and a freeze-thaw bag protection system.

[0007] To achieve the above objectives, the present invention adopts the following technical solution:

[0008] A freeze-thaw bag protection assembly for protecting a freeze-thaw bag connected to a tubular assembly;

[0009] The freeze-thaw bag protection assembly includes a protective shell and a receiving component. The protective shell and the receiving component cooperate with each other to form a receiving cavity for accommodating the freeze-thaw bag.

[0010] The protective shell and / or the receiving member have receiving grooves on their outer surfaces away from the receiving cavity for accommodating a portion of the pipe assembly;

[0011] A connecting portion is provided between the receiving cavity and the receiving groove, so that the free end of the tube assembly can extend through the connecting portion to the receiving groove and be received.

[0012] In the above solution, at least one of the protective shell and the receiving component has a receiving groove on its outer surface. This receiving groove is connected to the receiving cavity via a connecting part, meaning the free end of the pipe assembly can extend into the receiving groove through the connecting part, effectively accommodating the portion of the pipe assembly extending out of the receiving cavity. Furthermore, since the receiving groove is located on the outer surface of the protective shell, which has a relatively large area (i.e., the projected area along the thickness direction of the protective shell), the receiving groove can be sufficiently large to accommodate pipe assemblies of different lengths. This eliminates the need for specific designs for different types of pipe assemblies, reducing the design difficulty, processing difficulty, and processing cost of the protective assembly. Simultaneously, the receiving groove's location on the outer surface of the protective shell does not expand the extension area of ​​either the protective shell or the receiving component (i.e., the extension area along the plane of the laid-out freeze-thaw bag), effectively avoiding the difficulties of transporting the protective assembly, freeze-thaw bag, and pipe assembly as a whole.

[0013] It is worth noting that the "free end of the tube assembly" refers to the end furthest from the freeze-thaw bag. "Area" refers to the projected area along the thickness direction of the protective shell.

[0014] Preferably, the connecting portion is configured as a channel penetrating the protective shell;

[0015] The channel is located on the protective shell corresponding to the tube assembly.

[0016] In the above solution, the connecting part is a channel that penetrates the protective shell. That is, when the tube assembly passes through the channel, the channel penetrates the protective shell and the side wall formed on the protective shell can achieve circumferential restraint on the tube assembly. Compared with the tube assembly extending around the protective shell to the receiving groove (that is, the connecting part is formed on the outer periphery of the overall structure of the protective shell, rather than on the overall structure of the protective shell), it can avoid the tube assemblies stored on the two protective components from squeezing or colliding with each other during transportation, thereby avoiding damage to the tube assembly.

[0017] Furthermore, the channel is located at the corresponding tube assembly of the protective shell, which helps to shorten the minimum length of the tube assembly extending from the freeze-thaw bag to the receiving groove (that is, the length of the tube assembly in the receiving cavity). It also helps the free end of the tube assembly to extend from the receiving cavity through the connecting part to the receiving groove on the outer surface of the protective shell for sorting and storage. This reduces the free movement of the tube assembly, facilitates the orderly and neat storage of the tube assembly, and helps to reduce the damage to the tube assembly caused by its messy state.

[0018] Preferably, the receiving groove is formed by the protective shell recessing towards the receiving cavity, and the protective shell has side walls and a bottom wall corresponding to the receiving groove;

[0019] The projection of the bottom wall along the thickness direction of the protective shell at least covers the projection of the center of the freeze-thaw bag along the thickness direction of the protective shell; and / or, the side wall is provided with the connecting portion, and the connecting portion is configured as a channel penetrating the side wall, the channel being located on the protective shell corresponding to the tube assembly.

[0020] In the above solution, when the elastic deformation of the membrane material used to make the freeze-thaw bag changes greatly or when the liquid volume of the freeze-thaw bag is large, the center of the freeze-thaw bag is prone to excessive expansion. The projection of the bottom wall along the thickness direction of the protective shell at least covers the projection of the center of the freeze-thaw bag along the thickness direction of the protective shell. That is, when the freeze-thaw bag is placed in the containment cavity, the center of the freeze-thaw bag directly abuts against the bottom wall or the center of the freeze-thaw bag abuts against the bottom wall after the freeze-thaw bag expands and deforms, the bottom wall (which has a certain supporting strength and anti-deformation ability) can inhibit further expansion at the center of the freeze-thaw bag, thus avoiding the hidden danger of excessive expansion of the freeze-thaw bag and damage (such as causing the membrane material of the freeze-thaw bag to become thinner) or breakage (such as exceeding the elastic limit of its membrane material and breaking).

[0021] It is worth noting that the center of a freeze-thaw bag refers to the intersection of its multiple diagonals or the midpoint of its only diagonal, while the periphery of a freeze-thaw bag refers to the closed edge that surrounds and forms the inner cavity of the freeze-thaw bag.

[0022] By providing a connecting portion on the side wall, that is, the connecting portion is located closer to the edge of the tube assembly relative to the center of the freeze-thaw bag, it is beneficial to shorten the minimum length of the tube assembly from the freeze-thaw bag to the receiving groove (that is, the length of the tube assembly in the receiving cavity). This facilitates the free end of the tube assembly to extend from the receiving cavity through the connecting portion to the receiving groove on the outer surface of the protective shell for neat storage, reducing the free movement of the tube assembly, making it easier to store the tube assembly in an orderly and tidy manner, and helping to reduce the damage to the tube assembly caused by its messy state.

[0023] Preferably, the receiving groove includes an extension groove; the extension groove is formed from the connection position of the side wall and the bottom wall towards the recess of the receiving cavity; the extension groove is distributed along the periphery of the receiving groove;

[0024] and / or;

[0025] The receiving groove includes a receiving groove formed by the bottom wall recessing towards the receiving cavity.

[0026] In the above scheme, the extension groove is formed from the connection point of the bottom wall and side wall towards the receiving cavity, and the extension groove is distributed around the periphery of the receiving groove, which can increase the circumferential length of the extension groove to a certain extent. When the pipe assembly is stored, the pipe assembly can be distributed around the extension groove, which is beneficial for storing relatively long pipe assemblies. The protective shell corresponding to the position of the extension groove protrudes further towards the receiving cavity compared to the bottom wall. When the bottom wall abuts against the center of the freeze-thaw bag to suppress excessive expansion of the center of the freeze-thaw bag, the protruding part of the protective shell corresponding to the extension groove can further suppress excessive expansion of the freeze-thaw bag located on the periphery of the bottom wall.

[0027] Furthermore, when the bottom wall does not contact the freeze-thaw bag, the biological liquid stored inside the freeze-thaw bag may easily move during transportation due to shaking. The protruding part of the protective shell corresponding to the extension groove can limit the position of the freeze-thaw bag and ensure its stability.

[0028] Preferably, the channel is located within the extension groove, and there are multiple channels arranged at intervals within the extension groove;

[0029] And / or, the bottom of the receiving slot is further away from the opening end of the receiving slot than the bottom of the extending slot;

[0030] And / or, the bottom wall has a suppressing protrusion on its inner surface facing the receiving cavity; the suppressing protrusion is capable of abutting against the center of the freeze-thaw bag.

[0031] In the above scheme, the freeze-thaw bag can have one or more tube assemblies. When there are multiple tube assemblies, the connection positions between different tube assemblies and the freeze-thaw bag differ. Several channels spaced apart in the extension groove allow different tube assemblies to pass through, extending into the receiving groove via different channels. This ensures that the tube assemblies are more evenly distributed within the receiving groove, preventing the tube assemblies from stacking along the thickness of the protective shell and potentially exceeding the port of the receiving groove, or causing the connectors or sealing plugs at the free ends of the tube assemblies to protrude from the port of the receiving groove. Furthermore, the tube assemblies extend from the receiving cavity into the extension groove through the channels and are further housed within the receiving groove. The extension groove is formed by the inward indentation of the bottom and side walls towards the receiving cavity, which reduces the length of the tube assembly within the receiving cavity to a certain extent, reducing the free movement of the tube assembly and facilitating orderly and neat storage of the tube assembly. This helps reduce the breakage of the tube assembly caused by its disordered state.

[0032] Furthermore, the tube assembly typically includes a tube body and either a connector or a closure plug. One end of the tube body is connected to a freeze-thaw bag to form the fixed end of the tube assembly; the connector or closure plug is fixed to the end of the tube body away from the freeze-thaw bag to form the free end of the tube assembly. The free end of the tube assembly extends from the receiving cavity into the receiving groove through a channel. The tube body of the tube assembly is housed in the extension groove and the area between the extension groove and the receiving groove. The receiving groove can house the connector or closure plug, which facilitates the separate housing of the tube body and the connector or closure plug. The connector or closure plug is usually larger than the diameter of the tube body. The bottom of the receiving groove is further away from the opening of the receiving groove than the bottom of the extension groove. This design ensures that after the tube assembly is housed in the receiving groove, the central axis of the tube body and the connector or closure plug are collinear. This helps to avoid the loss caused by bending and offset at the connection between the tube body and the connector or closure plug due to misalignment of the central axes of the tube body and the connector or closure plug along the axial direction. Furthermore, the design of the extension groove and the storage groove makes the area of ​​the protective shell corresponding to the extension groove and the storage groove have an uneven structure, which is conducive to promoting the distribution of biological liquid in the freeze-thaw bag from the center of the freeze-thaw bag to the periphery, while avoiding the biological liquid from exerting a large squeezing force on the surrounding sealed area of ​​the freeze-thaw bag.

[0033] Furthermore, the formation of the suppression convexity can suppress the expansion process at the center of the freeze-thaw bag. At the same time, after the suppression convexity comes into contact with the freeze-thaw bag, it can apply a certain pressure force to the freeze-thaw bag to limit its movement and thus prevent the freeze-thaw bag from shifting.

[0034] Preferably, the protective shell has a plurality of hollow portions through it, and along the thickness direction of the protective shell, the projection of the hollow portion is located inside the projection of the extension groove and outside the projection of the suppression protrusion.

[0035] And / or,

[0036] The bottom wall includes several deformable portions, and the projections of the deformable portions are all located outside the projection of the suppressing convexity.

[0037] In the above scheme, one or more hollow and deformable portions are provided, and both the hollow and deformable portions are located between the extension groove and the suppression protrusion. This allows the protective shell to easily deform near the hollow portion or the corresponding deformable portion when subjected to force, thereby promoting the distribution of the biological feed liquid from the center to the periphery of the freeze-thaw bag. This results in a more uniform distribution of the biological feed liquid within the freeze-thaw bag, which is beneficial for improving the freezing uniformity of the freeze-thaw bag. Simultaneously, since the protective shell protrudes further towards the receiving cavity relative to the bottom wall, it can further suppress excessive expansion of the freeze-thaw bag at the periphery of the bottom wall, avoiding affecting the sealing performance of the freeze-thaw bag's periphery.

[0038] Meanwhile, the presence of a hollow section facilitates heat conduction and circulation, further enhancing the freezing uniformity and efficiency of the freeze-thaw bag.

[0039] Preferably, the receiving groove is provided with a coiled tube column; a portion of the tube assembly can be wound around the coiled tube column.

[0040] In the above scheme, the setting of the coil column is conducive to the winding and storage of the tube assembly, increases the stability of the tube assembly storage, prevents the tube assembly from falling out of the receiving groove, and also facilitates the orderly storage of the tube assembly.

[0041] Preferably, at least two coiled tubing columns are provided, and a tubing clamping gap is formed between adjacent coiled tubing columns. The tubing clamping gap is used to allow partial passage of the tubing assembly so that the tubing assembly is wound around at least one of the coiled tubing columns.

[0042] And / or,

[0043] The receiving groove includes a receiving groove, which is formed by the bottom wall recessing towards the receiving cavity, and the inner surface of the bottom wall corresponding to the position of the receiving groove has a corresponding suppressing protrusion; the coil column is disposed in the receiving groove;

[0044] And / or,

[0045] The projection of the boundary circle containing the outer perimeter of all the coils along the thickness direction of the protective shell covers the center of the freeze-thaw bag.

[0046] In the above scheme, when the tube body of the tube assembly is connected to a connector or a sealing plug, and the tube body is wound and stored on the coil column, the connector or sealing plug can be directly clamped by the tube clamping gap, or the tube body and the connector (or sealing plug) of the tube assembly can be located at opposite ends of the tube clamping gap, which helps to limit the tube body from detaching from the coil column and ensures the stability of the tube body storage. When the tube assembly only includes the tube body, the tube body can be directly press-fitted with the tube clamping gap, which helps to limit the movement of the tube body and further facilitates the storage of the tube body. It is also worth noting that when there are at least two coil column intervals, if there are multiple sets of tube assemblies, it is beneficial to distinguish different tube assemblies and store them in an orderly manner. If the tube assembly is long, multiple coil columns can be used to wind and store the tube assembly, avoiding the tube assembly being stored along the same coil column, which would cause the winding height along the coil column to be too high, making it easy to detach from the coil column or protrude from the receiving groove, thus causing difficulties in transportation.

[0047] Furthermore, the bottom wall tends to recess into the receiving cavity to form a receiving groove, and a suppressing protrusion is formed on the inner surface of the bottom wall corresponding to the receiving groove. On the one hand, the formed receiving groove facilitates the storage of connectors or sealing plugs; on the other hand, the suppressing protrusion can suppress excessive expansion of the center of the freeze-thaw bag. Moreover, the suppressing protrusion is formed simultaneously during the processing of the receiving groove on the bottom wall, eliminating the need for separate processing of the suppressing protrusion and reducing processing difficulty. The coiled tube column is placed in the receiving groove, which not only facilitates the storage of the tube assembly in the receiving groove but also increases the strength of the suppressing protrusion, preventing the suppressing protrusion from deforming due to the reaction force of the freeze-thaw bag.

[0048] Furthermore, since the coiled columns are spaced apart, the above scheme helps to ensure that at least one coiled column can be located at or near the center of the freeze-thaw bag. The coiled columns are connected to the bottom wall or protrude from the bottom wall locally away from the receiving cavity (the protrusion does not affect the thickness of the bottom wall itself), thereby increasing the structural strength of the location where the coiled column is located on the bottom wall and better suppressing the expansion of the center of the freeze-thaw bag.

[0049] Preferably, the sidewall and the bottom wall are integrally formed.

[0050] In the above solution, the sidewalls and bottom wall are integrally molded, meaning they are formed from a substrate (such as a base plate) of the same thickness. This ensures uniform thickness throughout the protective shell, guaranteeing uniform heat conduction and thus improving the freezing effect of the biological liquid inside the freeze-thaw bag. Furthermore, the integral molding process effectively reduces manufacturing difficulty and results in a stronger overall protective shell structure, effectively preventing localized breakage during deformation compared to a pieced-together structure.

[0051] Preferably, it further includes a latching part, which is connected between the protective shell and the receiving part;

[0052] The projection of the latching part along the thickness direction of the protective shell is located outside the projection of the receiving cavity along the thickness direction of the protective shell.

[0053] In the above solution, the snap-fit ​​part allows the protective shell to be opened and closed relative to the receiving part at any time. On the one hand, this facilitates the adjustment of the internal freeze-thaw bag; on the other hand, it allows the protective component to be used either once or repeatedly. Furthermore, considering that repeated opening and closing of the snap-fit ​​part could lead to structural failure or a decrease in the structural strength of the protective shell, thus affecting the freeze-thaw bag, the above solution also ensures that the projection of the snap-fit ​​part along the thickness direction of the protective shell is outside the projection of the receiving cavity along the thickness direction of the protective shell. This avoids the problem of structural failure or a decrease in the strength of the protective shell caused by repeated opening and closing of the snap-fit ​​part affecting the freeze-thaw bag.

[0054] Preferably, a reinforcing part is provided between the snap-fit ​​part and the receiving cavity.

[0055] In the above solution, the reinforcing part can be a raised rib or a thickened structure to increase the connection strength between the snap-fit ​​part and the receiving cavity, and avoid problems such as structural failure or strength reduction of the snap-fit ​​part under repeated opening and closing.

[0056] Furthermore, the reinforcement can correspond to the pipe assembly, that is, to the connecting part. It is easy to understand that, since the strength of the protective shell at the connecting part is low, it can enhance the structural strength of the outer periphery of the connecting part, thus preventing the pipe assembly and the periphery of the connecting part from interfering with each other and causing damage to the protective shell.

[0057] Preferably, the receiving component has the same structure as the protective shell, and the inner surface of the receiving component and the inner surface of the protective shell are arranged opposite to each other along the thickness direction of the protective shell to form a receiving cavity for accommodating the freeze-thaw bag;

[0058] or,

[0059] The receiving component has an inner side and an outer side, the inner side facing the freeze-thaw bag and arranged opposite to the inner surface of the protective shell along the thickness direction of the protective shell to form a receiving cavity for accommodating the freeze-thaw bag.

[0060] The receiving part is provided on the inner side of the receiving component to receive the freeze-thaw bag.

[0061] The inner surface of the protective shell has a suppressing protrusion, and the inner side of the receiving component has a limiting protrusion; the center of the freeze-thaw bag is located between the suppressing protrusion and the limiting protrusion.

[0062] And / or,

[0063] The receiving component is provided with a peripheral portion around its circumference;

[0064] The peripheral portion has a first wall surface and a second wall surface, the first wall surface being connected to the inner side surface of the receiving member, and the second wall surface being connected to the outer side surface of the receiving member;

[0065] The first wall surface is provided with a first shape, and the second wall surface is provided with a second shape. When the first wall surface of one of the receiving components is disposed opposite to the second wall surface of the other receiving component, the first shape and the second shape are complementary.

[0066] In the above scheme, by setting the suppressing convex and limiting convex from both sides of the freeze-thaw bag corresponding to the center of the freeze-thaw bag, excessive deformation of the center of the freeze-thaw bag can be suppressed.

[0067] Furthermore, complementary first and second shapes are formed on the peripheral portion of the receiving component that surrounds it circumferentially. When the protective components are stacked along the thickness direction of the protective shell, the first shape on one of the receiving components and the second shape on the other receiving component can complement each other, that is, form an interlocking fit. This allows a limiting fit to be formed between two adjacent receiving components that are stacked, preventing adjacent freeze-thaw bag protective components from moving or misaligning during the stacking process along the thickness direction, thus facilitating stable stacking and transportation.

[0068] The present invention also provides a freeze-thaw bag protection system having a freeze-thaw bag protection component as described above and a freeze-thaw bag contained within the freeze-thaw bag protection component.

[0069] Compared with the prior art, the present invention has at least the following beneficial effects:

[0070] 1. By providing a receiving groove on the outer surface of at least one of the protective shell and the receiving component, and the receiving groove communicating with the receiving cavity through a connecting part, the free end of the pipe assembly can extend to the receiving groove through the connecting part, thus effectively accommodating the portion of the pipe assembly extending out of the receiving cavity. Furthermore, since the receiving groove is located on the outer surface of the protective shell, which has a relatively large area (i.e., the projected area along the thickness direction of the protective shell), the receiving groove can be ensured to have a sufficiently large area to accommodate pipe assemblies of different lengths. This eliminates the need for specific designs for different types of pipe assemblies, reducing the design difficulty, processing difficulty, and processing cost of the protective assembly. Simultaneously, the receiving groove being located on the outer surface of the protective shell does not expand the extension area of ​​either the protective shell or the receiving component (i.e., the extension area along the plane of the laid-out freeze-thaw bag), effectively avoiding the difficulties of transporting the protective assembly, freeze-thaw bag, and pipe assembly as a whole.

[0071] 2. By setting the connecting part to form a channel through the protective shell, that is, when the tube assembly passes through the channel, the channel passes through the protective shell and the side wall surface formed on the protective shell can achieve circumferential restraint on the tube assembly. Compared with the tube assembly extending around the protective shell to the receiving groove (that is, the connecting part is formed on the outer periphery of the protective shell), it can avoid the tube assemblies stored on the two protective components from squeezing or colliding with each other during transportation, thereby avoiding damage or breakage of the tube assembly.

[0072] Furthermore, the channel is located at the corresponding tube assembly of the protective shell, which helps to shorten the minimum length of the tube assembly extending from the freeze-thaw bag to the receiving groove (that is, the length of the tube assembly in the receiving cavity). It also helps the free end of the tube assembly to extend from the receiving cavity through the connecting part to the receiving groove on the outer surface of the protective shell for sorting and storage. This reduces the free movement of the tube assembly, facilitates the orderly and neat storage of the tube assembly, and helps to reduce the damage to the tube assembly caused by its messy state.

[0073] 3. The extension groove is formed from the connection point of the bottom wall and side wall towards the receiving cavity, and the extension groove is distributed around the periphery of the receiving groove, which is beneficial for accommodating relatively long pipe assemblies. The protective shell, corresponding to the position of the extension groove, protrudes further towards the receiving cavity compared to the bottom wall. When the bottom wall abuts against the center of the freeze-thaw bag to suppress excessive expansion at the center of the freeze-thaw bag, the protruding part of the protective shell corresponding to the extension groove can further suppress excessive expansion of the freeze-thaw bag at the periphery of the bottom wall. Furthermore, since the freeze-thaw bag is not in contact with the bottom wall during transportation, the sloshing of the stored biological material liquid can easily cause the freeze-thaw bag to shift. The protruding part of the protective shell corresponding to the extension groove can limit the position of the freeze-thaw bag, ensuring its stability. Attached Figure Description

[0074] To more clearly illustrate the specific embodiments of the present invention or the technical solutions in the prior art, the drawings used in the description of the specific embodiments or the prior art will be briefly introduced below. Obviously, the drawings described below are some embodiments of the present invention. For those skilled in the art, other drawings can be obtained from these drawings without creative effort.

[0075] Figure 1 This is a schematic diagram of a first embodiment of the freeze-thaw bag protection assembly provided by the present invention.

[0076] Figure 2 for Figure 1 A schematic diagram of the structure of the freeze-thaw bag protection assembly when the freeze-thaw bag is installed.

[0077] Figure 3 for Figure 2 A structural diagram from another perspective (top view).

[0078] Figure 4 for Figure 3 A cross-sectional view along section AA shows that the bottom of the extended groove tends to bulge into the receiving cavity relative to the bottom wall.

[0079] Figure 5 for Figure 4 An enlarged diagram of position D1.

[0080] Figure 6 for Figure 4 An enlarged view of position D2 in the middle.

[0081] Figure 7 for Figure 3 A schematic diagram of the structure of the freeze-thaw bag.

[0082] Figure 8 for Figure 2 A structural diagram from another perspective.

[0083] Figure 9 for Figure 8 A schematic diagram of the structure of the protective shell.

[0084] Figure 10 for Figure 9 A schematic diagram of a section cut along one of the cutting planes.

[0085] Figure 11 for Figure 9 A schematic diagram of a section cut along another cutting plane.

[0086] Figure 12 for Figure 8 A schematic diagram of the structure of the middle connector.

[0087] Figure 13 for Figure 12 A cross-sectional view of the middle connector.

[0088] Figure 14 two Figure 1 The diagram shows the structure of the freeze-thaw bag protection components when stacked.

[0089] Figure 15 The bottom of the extension groove extends in the same horizontal direction as the bottom wall.

[0090] Figure 16 for Figure 15 A cross-sectional view of the inner protective shell.

[0091] Figure 17 This is a schematic diagram of the structure of a second embodiment of the freeze-thaw bag protection component provided by the present invention.

[0092] Figure 18 for Figure 17 A cross-sectional diagram.

[0093] Figure 19 This is a schematic diagram of the structure of a third embodiment of the freeze-thaw bag protection assembly provided by the present invention.

[0094] Figure 20 This is a schematic diagram of the structure of Embodiment 4 of the freeze-thaw bag protection component provided by the present invention.

[0095] Figure 21 for Figure 20 A schematic diagram of the structure of the freeze-thaw bag protection assembly when the freeze-thaw bag is installed.

[0096] Figure 22 for Figure 21 A structural diagram from another perspective.

[0097] Figure 23 for Figure 22 A cross-sectional view along section BB.

[0098] Explanation of reference numerals in the attached figures:

[0099] 100. Pipe assembly; 101. Pipe body; 102. Connector; 200. Freeze-thaw bag; 1. Protective shell; 111. Inner surface; 112. Outer surface; 11. Side wall; 12. Bottom wall; 121. Deformation part; 1211. Arc connection part; 1212. Through groove; 13. Hollow part; 2. Receiving part; 211. Inner side; 212. Outer side; 21. Receiving groove; 22. Restricting protrusion; 23. Peripheral part; 231. First wall surface; 232. Second wall surface; 3. Receiving cavity; 4. Receiving groove; 41. Extension groove; 42. Storage groove; 5. Channel; 6. Suppression protrusion; 7. Coil column; 70. Pipe clamping gap; 8. Buckle part; 81. Plate; 82. Bayonet; 83. Buckle body; 84. Locking part; 9. Reinforcing part. Detailed Implementation

[0100] The technical solution of the present invention will now be clearly and completely described with reference to the accompanying drawings. Obviously, the described embodiments are only some, not all, of the embodiments of the present invention. Based on the embodiments of the present invention, all other embodiments obtained by those skilled in the art without creative effort are within the scope of protection of the present invention.

[0101] In the description of this invention, it should be noted that the terms "center," "upper," "lower," "left," "right," "vertical," "horizontal," "inner," and "outer," etc., indicate the orientation or positional relationship based on the orientation or positional relationship shown in the accompanying drawings. They are used only for the convenience of describing the invention and for simplifying the description, and do not indicate or imply that the device or element referred to must have a specific orientation, or be constructed and operated in a specific orientation. Therefore, they should not be construed as limitations on the invention. Furthermore, the terms "first," "second," and "third" are used for descriptive purposes only and should not be construed as indicating or implying relative importance.

[0102] In the description of this invention, it should be noted that, unless otherwise explicitly specified and limited, the terms "installation," "connection," and "linking" should be interpreted broadly. For example, they can refer to a fixed connection, a detachable connection, or an integral connection; they can refer to a mechanical connection or an electrical connection; they can refer to a direct connection or an indirect connection through an intermediate medium; and they can refer to the internal connection of two components. Those skilled in the art can understand the specific meaning of the above terms in this invention based on the specific circumstances.

[0103] Example 1

[0104] See Figures 1 to 14 This invention provides a freeze-thaw bag protection assembly for protecting a freeze-thaw bag 200 connected to a tube assembly 100. The tube assembly 100 is used to deliver biological feed solution into the freeze-thaw bag 200 or to output the biological feed solution from the freeze-thaw bag 200. Generally, the tube assembly 100 typically includes a tube body 101 and either a connector 102 or a sealing plug. One end of the tube body 101 is fixedly connected to the freeze-thaw bag 200 to form a fixed end of the tube assembly 100; the connector 102 or sealing plug is fixed to the end of the tube body 101 away from the freeze-thaw bag 200 to form a free end of the tube assembly 100. The freeze-thaw bag 200 is used to store or transport biological feed solution, and it may have one or more tube assemblies 100. The freeze-thaw bag protection assembly protects the freeze-thaw bag 200 from damage caused by collision or compression during transportation or operation, and also prevents the freeze-thaw bag 200 from being punctured by sharp objects.

[0105] Specifically, the aforementioned freeze-thaw bag protection assembly includes a protective shell 1 and a receiving component 2. The protective shell 1 and the receiving component 2 cooperate with each other to form a receiving cavity 3 for accommodating the freeze-thaw bag 200. "Relative arrangement" means that along the thickness direction of the protective shell 1, the protective shell 1 and the receiving component 2 are arranged face-to-face, either directly opposite each other or approximately directly opposite; that is, along the thickness direction of the protective shell 1, the projections of the protective shell 1 and the receiving component 2 have a large overlapping area, and this overlapping area corresponds to the position where the receiving cavity 3 is formed; in the use state, the protective shell 1 and the receiving component 2 are placed on a horizontal surface.

[0106] Furthermore, the protective shell 1 has an inner surface 111 and an outer surface 112 disposed opposite to each other, and the receiving member 2 includes an inner side 211 and an outer side 212, with the inner side 211 facing the freeze-thaw bag 200. The inner side 211 and the inner surface 111 are arranged opposite to each other (directly or approximately directly opposite each other) along the thickness direction of the protective shell 1 to form a receiving cavity 3 for receiving the freeze-thaw bag 200. Here, "inner" indicates a position relatively closer to the receiving cavity 3 (i.e., closer to the freeze-thaw bag 200), and "outer" indicates a position relatively farther away from the receiving cavity 3 (i.e., farther away from the freeze-thaw bag 200). For example, the inner side 211 of the receiving member 2 is closer to the freeze-thaw bag 200 than its outer side 212, and the inner surface 111 of the protective shell 1 is also closer to the freeze-thaw bag 200 than its outer surface 112. The freeze-thaw bag 200 is located inside the receiving cavity 3 and is limited by the receiving part 2 and the protective shell 1 (for example, by direct contact with the limiting part, or by the freeze-thaw bag 200 deforming to a certain extent before contact with the limiting part) to ensure the stable placement of the freeze-thaw bag 200 inside the receiving cavity 3.

[0107] It is worth noting that the thickness directions of the protective shell 1, the receiving component 2, and the freeze-thaw bag 200 can all be understood as... Figure 4 The direction of H shown or the opposite direction of H.

[0108] Furthermore, the outer surface 112 of the protective shell 1, away from the receiving cavity 3, is provided with a receiving groove 4 for accommodating a portion of the tube assembly 100. A connecting portion is provided between the receiving cavity 3 and the receiving groove 4 so that the free end of the tube assembly 100 can extend through the connecting portion into the receiving groove 4 and be stored therein. That is, when the freeze-thaw bag 200 is located inside the receiving cavity 3, the free end of the tube assembly 100 can extend through the connecting portion into the receiving groove 4, thereby effectively storing the portion of the tube assembly 100 that extends out of the receiving cavity 3.

[0109] It is easy to understand that since the receiving groove 4 is located on the outer surface 112 of the protective shell 1, and the outer surface 112 has a relatively large area, the receiving groove 4 can be provided with a sufficiently large area to accommodate pipe assemblies 100 of different lengths. This eliminates the need for specific designs for different models of pipe assemblies 100, reducing the design difficulty, processing difficulty, and processing cost of the protective assembly. At the same time, the receiving groove 4 is located on the outer surface 112 of the protective shell 1, which does not expand the extended area of ​​either the protective shell 1 or the receiving component 2 (i.e., the extended area along the plane of the laid-out freeze-thaw bag 200), effectively avoiding the difficulties in transporting the protective assembly, freeze-thaw bag 200, and pipe assembly 100 as a whole. It is worth noting that the aforementioned "area" refers to the projected area along the thickness direction of the protective shell 1.

[0110] See Figures 1 to 7The receiving groove 4 is formed by the protective shell 1 tending to be recessed closer to the receiving cavity 3. The protective shell 1 has a side wall 11 and a bottom wall 12 corresponding to the receiving groove 4. That is, the outer surface of the side wall 11 and the bottom wall 12 (a part of the outer surface 112 of the protective shell 1) corresponds to the receiving groove 4.

[0111] Specifically, because the elastic deformation of the membrane material used to make the freeze-thaw bag 200 varies greatly, or when the liquid volume of the freeze-thaw bag 200 is large, the center of the freeze-thaw bag 200 is prone to excessive expansion. Therefore, to avoid excessive expansion at the center of the freeze-thaw bag 200, the projection of the bottom wall 12 along the thickness direction of the protective shell 1 covers the projection of the center of the freeze-thaw bag 200 along the thickness direction of the protective shell 1. That is, when the freeze-thaw bag 200 is placed in the receiving cavity 3, and the center of the freeze-thaw bag 200 directly abuts against the bottom wall 12, or when the center of the freeze-thaw bag 200 abuts against the bottom wall 12 after the freeze-thaw bag 200 has expanded and deformed, the bottom wall 12 (which has a certain supporting strength and anti-deformation ability) can inhibit further expansion at the center of the freeze-thaw bag 200, thus avoiding the potential danger of excessive expansion of the freeze-thaw bag 200 and damage (such as causing the membrane material of the freeze-thaw bag 200 to become thinner) or breakage (such as exceeding the elastic limit of its membrane material and rupturing).

[0112] It is worth noting that the center of the freeze-thaw bag 200 refers to point C, the intersection of its multiple diagonals (see [reference]). Figure 7 Alternatively, it can be determined by the midpoint of the only diagonal line. "Periphery of the freeze-thaw bag 200" refers to the closed edge that surrounds and forms the inner cavity of the freeze-thaw bag 200. In this embodiment, the projection of the bottom wall 12 along the thickness direction of the protective shell covers the center of the freeze-thaw bag 200 and a local area that diffuses from the center of the freeze-thaw bag 200 to the periphery, specifically determined by the contact area between the bottom wall 12 itself and the freeze-thaw bag 200.

[0113] Furthermore, the connecting portion is configured as a channel 5 that penetrates the protective shell 1 (specifically, the side wall 11 of the protective shell 1). That is, when the tube assembly 100 penetrates the channel 5, the channel 5 penetrates the protective shell 1 and the side wall surface formed on the protective shell 1 can achieve circumferential restraint on the tube assembly 100. Compared to the tube assembly 100 extending around the protective shell 1 to the receiving groove 4 (that is, the connecting portion is formed on the outer periphery of the overall structure of the protective shell 1, rather than on the overall structure of the protective shell 1), it can avoid the tube assemblies 100 stored on the two protective components from squeezing or colliding with each other during transportation, thereby avoiding damage or breakage of the tube assembly 100.

[0114] Furthermore, the channel 5 is located at the corresponding tube assembly 100 on the protective shell 1, which helps to shorten the minimum length of the tube assembly 100 extending from the freeze-thaw bag 200 to the receiving groove 4 (that is, the length of the tube assembly 100 in the receiving cavity 3). It also helps to organize and store the free end of the tube assembly 100 from the receiving cavity 3 through the connecting part to the receiving groove 4 on the outer surface 112 of the protective shell 1. This reduces the free movement of the tube assembly 100, facilitates the orderly and neat storage of the tube assembly 100, and helps to reduce the damage to the tube assembly 100 caused by its messy state.

[0115] Specifically, see Figures 1 to 11 The receiving groove 4 includes an extension groove 41; the extension groove 41 is formed by the indentation of the connection position between the side wall 11 and the bottom wall 12 towards the receiving cavity 3; the extension groove 41 is distributed along the periphery of the receiving groove 4. That is, the extension groove 41 is arranged around the periphery of the receiving groove 4, which can increase the length of the extension groove 41 to a certain extent, thereby facilitating the storage of the relatively long pipe assembly 100.

[0116] Since the extension groove 41 is formed by the connection between the side wall 11 and the bottom wall 12 and tends to be recessed towards the receiving cavity 3, the protective shell 1 corresponding to the extension groove 41 protrudes towards the receiving cavity 3 relative to the bottom wall 12. In some specific embodiments, the bottom of the extension groove 41 protrudes towards the receiving cavity 3 relative to the bottom wall 12. When the bottom wall 12 abuts against the center of the freeze-thaw bag 200 to suppress excessive expansion of the center of the freeze-thaw bag 200, the protruding part of the protective shell 1 corresponding to the extension groove 41 can further suppress excessive expansion of the freeze-thaw bag 200 located on the periphery of the bottom wall 12. Furthermore, since when the bottom wall 12 does not abut against the freeze-thaw bag 200, the biological liquid stored inside the freeze-thaw bag 200 is prone to displacement during transportation due to shaking, the protruding part of the protective shell 1 corresponding to the extension groove 41 can limit the position of the freeze-thaw bag 200 and ensure its stability.

[0117] Furthermore, the channel 5 is located within the extension groove 41, which facilitates the extension of the tube assembly 100 into the extension groove 41 and allows the tube assembly 100 to be partially housed within the extension groove 41 (especially when the tube body 101 of the tube assembly 100 is relatively long).

[0118] Furthermore, since there are different connection positions between different tube assemblies 100 and the freeze-thaw bag 200 when multiple tube assemblies 100 are provided, in this embodiment, two channels 5 are provided, and the two channels 5 are spaced apart in the extension groove 41, so that different tube assemblies 100 can pass through, so that different tube assemblies 100 can extend into the receiving groove 4 through different channels 5, so that several tube assemblies 100 can be more evenly distributed in the receiving groove 4, thereby avoiding the hidden danger that multiple tube assemblies 100 are stacked along the thickness direction of the protective shell 1, which may cause the tube assemblies 100 to easily exceed the port of the receiving groove 4, and cause the connector 102 or sealing plug connected to the free end of the tube assembly 100 to protrude from the port of the receiving groove 4.

[0119] Furthermore, it should be understood that since the tube assembly 100 extends from the receiving cavity 3 into the extension groove 41 through the channel 5 and is further housed in the receiving groove 4, and the extension groove 41 is formed by the indentation of the bottom wall 12 and the side wall 11 in the direction of the receiving cavity 3, the length of the tube assembly 100 in the receiving cavity 3 can be further reduced to a certain extent, reducing the free movement of the tube assembly 100, facilitating the orderly and regular storage of the tube assembly 100, and helping to reduce the damage to the tube assembly 100 caused by the messy state of the tube assembly 100.

[0120] Specifically, see Figures 1 to 11 The receiving groove 4 also includes a receiving groove 42, the bottom of which is further away from the opening end of the receiving groove 4 than the bottom of the extension groove 41. When the free end of the tube assembly 100 extends from the receiving cavity 3 into the receiving groove 4 through the channel 5, the tube body 101 of the tube assembly 100 is received in the extension groove 41 and the area between the extension groove 41 and the receiving groove 42. The receiving groove 42 can receive the connector 102 or the sealing plug, which is beneficial for distinguishing and storing the tube body 101 and the connector 102 or the sealing plug. Furthermore, since the size of the connector 102 or the sealing plug is usually larger than the diameter of the tube body 101, the bottom of the receiving groove 42 is further away from the opening end of the receiving groove 4 than the bottom of the extension groove 41. This arrangement ensures that after the tube assembly 100 is received into the receiving groove 4, the central axis of the tube body 101 of the tube assembly 100 is collinear with that of the connector 102 or the sealing plug. This helps to avoid the damage caused by the bending and offset of the connection between the tube body 101 and the connector 102 or the sealing plug due to the misalignment of the central axis of the tube body 101 and the connector 102 or the sealing plug along the axial direction.

[0121] In addition, when the extension groove 41 and the storage groove 42 are provided at the same time, the area of ​​the protective shell 1 corresponding to the extension groove 41 and the storage groove 42 has an uneven structure, which is conducive to promoting the distribution of biological liquid in the freeze-thaw bag 200 from the center of the freeze-thaw bag 200 to the periphery, while avoiding the biological liquid from exerting a large squeezing force on the surrounding sealing area of ​​the freeze-thaw bag 200.

[0122] Furthermore, the receiving groove 42 is formed by the indentation of the bottom wall 12 towards the receiving cavity 3, and the inner surface 111 of the bottom wall 12 corresponding to the position of the receiving groove 42 forms a suppressing protrusion 6. That is, the outer surface of the suppressing protrusion 6 (which is part of the outer surface 112 of the protective shell 1) corresponds to the wall of the receiving groove 42, and the inner surface of the suppressing protrusion 6 (which is part of the inner surface 111 of the protective shell 1) can abut against the center of the freeze-thaw bag 200. For example, the suppressing protrusion 6 can abut against the center of the freeze-thaw bag 200 directly, or there can be a certain distance between the suppressing protrusion 6 and the freeze-thaw bag 200, so that when the center of the freeze-thaw bag 200 expands, it can abut against the suppressing protrusion 6. This arrangement facilitates the storage of the connector 102 or the sealing plug by forming the receiving groove 42, and suppresses excessive expansion of the center of the freeze-thaw bag 200 by the suppressing protrusion 6. Moreover, the suppressing protrusion 6 is formed simultaneously during the processing of the receiving groove 42 on the bottom wall 12, eliminating the need to process the suppressing protrusion 6 separately and reducing the processing difficulty.

[0123] It is easy to understand that the formation of the inhibition convex 6 can suppress the expansion process at the center of the freeze-thaw bag 200. At the same time, after the inhibition convex 6 comes into contact with the freeze-thaw bag 200, it can apply a certain pressure force to the freeze-thaw bag 200 to restrict the movement of the freeze-thaw bag 200 and thus prevent the freeze-thaw bag 200 from shifting.

[0124] Of course, in other embodiments, the suppression protrusion 6 may also be configured as a plurality of protrusions formed on the inner surface 111 of the bottom wall 12 facing the receiving cavity 3.

[0125] See Figures 1 to 11 The receiving groove 4 is provided with a coiled column 7; a portion of the tube assembly 100 can be wound around the coiled column 7, which is conducive to the winding and storage of the tube assembly 100, increases the stability of the storage of the tube assembly 100, prevents the tube assembly 100 from falling out of the receiving groove 4, and at the same time, is conducive to the orderly storage of the tube assembly 100.

[0126] Specifically, three coiled tubing columns 7 are provided and arranged linearly. A clamping gap 70 is formed between adjacent coiled tubing columns 7. The clamping gap 70 is used for partial passage of the tubing assembly 100, allowing the tubing assembly 100 to pass through different clamping gaps 70 sequentially and wind around different coiled tubing columns 7, thus improving the stability of the winding of the tubing assembly 100. Specifically, when the tubing body 101 of the tubing assembly 100 is connected to a connector 102 or a sealing plug, and the tubing body 101 is wound and stored on the coiled tubing column 7, the connector 102 or sealing plug can be directly clamped through the clamping gap 70. Alternatively, the tubing body 101 and the connector 102 (or sealing plug) of the tubing assembly 100 can be located at opposite ends of the clamping gap 70, thereby helping to prevent the tubing body 101 from detaching from the coiled tubing column 7 and ensuring the stability of the storage of the tubing body 101. When the tube assembly 100 includes only the tube body 101, the tube body 101 can be directly pressurized with the tube clamping gap 70, which helps to restrict the movement of the tube body 101 and further facilitates the storage of the tube body 101.

[0127] It is worth noting that when the number of coiled columns 7 is more than one, if there are multiple sets of tube assemblies 100, it is beneficial to distinguish and store different tube assemblies 100 in an orderly manner. If the tube assembly 100 is long, it can be wound and stored by multiple coiled columns 7, avoiding the tube assembly 100 being wound too high along the axial direction of the coiled column 7 when stored along the same coiled column 7, which may cause it to easily detach from the coiled column 7 or protrude from the receiving groove 4, thus causing difficulties in transportation.

[0128] Furthermore, the boundary circle containing the outer perimeter of all coil columns 7 (see...) Figure 3 The projection of C1 along the thickness direction of the protective shell 1 covers the center of the freeze-thaw bag 200. Since the coils 7 are spaced apart, this method helps to ensure that at least one coil 7 can be located at or near the center of the freeze-thaw bag 200. The coils 7 are connected to the bottom wall 12 or are formed by protruding from the bottom wall 12 locally away from the receiving cavity 3 (the protrusion does not affect the thickness of the bottom wall 12 itself), thereby increasing the structural strength of the location of the bottom wall 12 where the coils 7 are located, and thus better suppressing the expansion of the center of the freeze-thaw bag 200.

[0129] Specifically, in this embodiment, the coil column 7 is disposed within the receiving groove 42. At this time, since the inner surface 111 of the bottom wall 12 corresponding to the position of the receiving groove 42 forms a suppressing protrusion 6, and the coil column 7 is disposed within the receiving groove 42 (i.e., on the side away from the suppressing protrusion 6), it is advantageous to store the tube assembly 100 (especially the connector 102 or sealing plug of the tube assembly 100) in the receiving groove 42, and it can also increase the structural strength of the suppressing protrusion 6, preventing the suppressing protrusion 6 from deforming due to the reaction force of the freeze-thaw bag 200.

[0130] Of course, in other embodiments, two, four or more coiled columns 7 may be provided, and the multiple coiled columns 7 may be arranged in a multi-ring circular array structure or dispersed in the receiving groove 4.

[0131] See Figures 1 to 7 The protective shell 1 has several hollow portions 13 extending through it. Each hollow portion 13 is a through groove penetrating the protective shell 1. Along the thickness direction of the protective shell 1, the projection of the hollow portion 13 is located inside the projection of the extension groove 41 and outside the projection of the suppression protrusion 6. That is, the hollow portion 13 is located between the extension groove 41 and the suppression protrusion 6 on the protective shell 1. This allows the portion of the protective shell 1 near the hollow portion 13 to deform more easily when subjected to force, thereby promoting the distribution of the biological liquid from the center of the freeze-thaw bag 200 to its periphery. This results in a more uniform distribution of the biological liquid within the freeze-thaw bag 200, improving the freezing uniformity of the freeze-thaw bag 200. Simultaneously, because the protective shell 1 protrudes further towards the receiving cavity 3 relative to the bottom wall 12 at the position corresponding to the extension groove 41, it can further suppress excessive expansion of the freeze-thaw bag 200 around the bottom wall 12, avoiding affecting the sealing performance of the freeze-thaw bag 200's periphery. In addition, the hollow section 13 is designed to promote heat conduction and circulation, further improving the freezing uniformity and efficiency of the freeze-thaw bag 200.

[0132] Furthermore, in order to further promote the distribution of biological liquid from the center of the freeze-thaw bag 200 to the periphery of the freeze-thaw bag 200, a number of deformation parts 121 can be provided on the bottom wall 12, and the projections of the deformation parts 121 are all located outside the projection of the suppression protrusion 6.

[0133] Specifically, the deformable part 121 includes an arc connecting part 1211 and a through groove 1212. The arc connecting part 1211 connects the extension groove 41 and the receiving groove 42, and the through groove 1212 passes through the arc connecting part 1211. The through groove 1212 is provided on the outer side of each of the four edges of the receiving groove 42.

[0134] Of course, in other embodiments, the deformable part 121 may also be configured as a corrugated structure, which may be connected between the extension groove 41 and the receiving groove 42.

[0135] It is easy to understand that the hollow part 13 and the deformable part 121 have the same effect, and they can be set at the same time or separately. When the hollow part 13 and the deformable part 121 are set at the same time, along the thickness direction of the protective shell 1, the projection of the deformable part 121 is located between the projection of the suppressing protrusion 6 and the projection of the hollow part 13.

[0136] See Figures 4 to 11Since the receiving groove 4 (including the extension groove 41 and the receiving groove 42), the hollow part 13, the deformation part 121, the channel 5, the suppression protrusion 6, the coil column 7, etc. are all formed on the protective shell 1, the side wall 11 and the bottom wall 12 are integrally formed for ease of processing. That is, the side wall 11 and the bottom wall 12 are formed by processing a substrate (such as a substrate) of the same thickness, which ensures that the thickness of the entire protective shell 1 is uniform throughout, and ensures the uniformity of heat conduction, which is beneficial to ensuring the freezing effect of the biological liquid in the freeze-thaw bag 200. In addition, the integral forming process not only effectively reduces the processing difficulty, but also makes the entire protective shell 1 structurally stronger. Compared with the spliced ​​structure, it can effectively avoid local breakage of the protective shell 1 during deformation.

[0137] Specifically, it can be formed by stamping (such as extension groove 41, receiving groove 42, suppression protrusion 6, coil column 7, etc.) and milling (such as hollow part 13, channel 5, etc.) on a whole substrate.

[0138] See Figures 1 to 4 The freeze-thaw bag protection assembly also includes a buckle part 8, which is connected between the protective shell 1 and the receiving part 2, thereby enabling the protective shell 1 to be opened and closed relative to the receiving part 2 at any time. On the one hand, it is convenient to adjust the internal freeze-thaw bag 200, and on the other hand, it enables the protection assembly to be used once or repeatedly.

[0139] Furthermore, the latching part 8 includes a first mating part and a second mating part. The first mating part is fixedly installed on the protective shell 1, and the second mating part is fixedly installed on the receiving part 2. The first mating part includes a plate 81 and a bayonet 82, and the second mating part includes a buckle body 83 fixedly installed on the receiving part 2. The buckle body 83 can engage with the bayonet 82.

[0140] It is easy to understand that the plate 81 can deform to a certain extent. When the plate 81 is subjected to force away from the end connected to the protective shell 1, the buckle 83 will disengage from the bayonet 82. At this time, the protective shell 1 and the receiving part 2 can be opened. When the buckle 83 is inserted into the bayonet 82, the protective shell 1 and the receiving part 2 are connected.

[0141] Furthermore, considering that the repeated opening and closing of the latching part 8 may cause structural failure of the protective shell 1 or reduce the structural strength of the protective shell 1, thereby affecting the freeze-thaw bag 200, in this embodiment, the projection of the latching part 8 along the thickness direction of the protective shell 1 is located outside the projection of the receiving cavity 3 along the thickness direction of the protective shell 1, so as to avoid the problem that the repeated opening and closing of the latching part 8 may cause structural failure of the protective shell 1 or reduce the strength of the protective shell 1, which may affect the freeze-thaw bag 200.

[0142] Furthermore, a reinforcing part 9 is provided between the latching part 8 and the receiving cavity 3. Specifically, the reinforcing part 9 can be a raised rib or a structural thickening, which can increase the connection strength between the latching part 8 and the receiving cavity 3, and can avoid problems such as structural failure or strength reduction of the latching part 8 under repeated opening and closing.

[0143] Furthermore, the reinforcing part 9 corresponds to the pipe assembly 100, that is, to the connecting part (channel 5). It is easy to understand that since the strength of the protective shell 1 at the connecting part is low, the setting of the reinforcing part 9 at the pipe assembly 100 can enhance the structural strength of the outer periphery of the connecting part, and prevent the pipe assembly 100 from interfering with the periphery of the connecting part (that is, the wall of the channel 5) and causing damage to the protective shell 1.

[0144] See Figures 1 to 6 ,as well as Figures 12 to 14 The inner side 211 of the receiving part 2 is provided with a receiving part to receive the freeze-thaw bag 200.

[0145] Specifically, the receiving part is configured as a receiving groove 21, which is formed by the receiving member 2 protruding outward in a direction away from the receiving cavity 3. When the freeze-thaw bag 200 is placed in the receiving groove 21, the periphery of the freeze-thaw bag 200 is limited by the side wall of the receiving groove 21, and the side of the freeze-thaw bag 200 is supported by the bottom surface of the receiving groove 21, so that the freeze-thaw bag 200 can be stably placed in the receiving groove 21. At the same time, it can also prevent the freeze-thaw bag 200 from moving when the protective shell 1 is opened and closed.

[0146] It is easy to understand that the receiving member 2 protrudes outward in a direction away from the receiving cavity 3 to form an outward protrusion on the receiving member 2, and the inner side of the outward protrusion (which is part of the inner side 211 of the receiving member 2) corresponds to the wall of the receiving groove 21.

[0147] Furthermore, the inner surface 211 of the receiving part 2 has a limiting protrusion 22, which is positioned opposite the suppressing protrusion 6 in the thickness direction of the protective shell 1, so that the center of the freeze-thaw bag 200 is located between the suppressing protrusion 6 and the limiting protrusion 22, thereby further preventing excessive deformation of the center of the freeze-thaw bag 200.

[0148] Furthermore, the receiving part 2 is provided with a peripheral portion 23 around its circumference, and the projection of the peripheral portion 23 is located outside the projection of the protective shell 1 along the thickness direction of the protective shell 1.

[0149] Specifically, the peripheral portion 23 has a first wall surface 231 and a second wall surface 232. The first wall surface 231 is connected to the inner side surface 211 of the receiving member 2, and the second wall surface 232 is connected to the outer side surface 212 of the receiving member 2. The first wall surface 231 has a first shape, and the second wall surface 232 has a second shape. When the first wall surface 231 of one receiving member 2 is opposite to the second wall surface 232 of the other receiving member 2, the first shape and the second shape are complementary.

[0150] See Figure 14 When the protective components are stacked along the thickness direction of the protective shell 1, the first shape on one of the receiving parts 2 and the second shape on the other receiving part 2 can complement each other, that is, form a plug-in fit, which can make the two adjacent receiving parts 2 stacked together form a limiting fit, preventing the adjacent freeze-thaw bag 200 protective components from moving or misaligning during the stacking process along the thickness direction, and facilitating stable stacking and transportation.

[0151] See Figures 15 to 16 In some other embodiments, the bottom of the extension groove 41 extends in the same horizontal direction as the bottom wall 12.

[0152] Example 2

[0153] See Figure 17 and Figure 18 Based on the above embodiment one, the difference in this embodiment is that the connecting part is formed on the outer periphery of the protective shell 1, and is not provided on the main body structure of the protective shell 1. Compared with providing a through channel on the protective shell 1, the method adopted in this embodiment can effectively ensure the structural strength of the protective shell 1. When the protective shell 1 and the receiving part 2 cooperate with each other to limit the freeze-thaw bag, the protective shell 1 can be prevented from undergoing excessive deformation.

[0154] Specifically, the protective shell 1 has two long sides arranged opposite each other and a short side connecting the two long sides, and the reinforcing part 9 is provided on the two short sides of the protective shell 1. Correspondingly, the receiving part 2 also has two long sides arranged opposite each other and a short side connecting the two long sides, and there is a certain distance between the two long sides of the protective shell 1 and the corresponding two long sides on the receiving part 2. This distance allows the pipe body 101 and the connector 102 of the pipe assembly 100 to pass through. That is, this distance allows the free end of the pipe assembly 100 to extend from the receiving cavity 3 to the receiving groove 4.

[0155] It is worth noting that this spacing can correspond to a local area or the entire area of ​​the long side of the protective shell 1.

[0156] In this embodiment, a local area is preferred, and a connecting part is provided on both long sides. The two connecting parts are symmetrically distributed about the reinforcing part 9, so that the pipe assembly 100 at different positions can extend to the receiving groove 4 through different connecting parts, and the force on both sides of the protective shell 1 can be more even, increasing the stability of the connection between the protective shell 1 and the receiving part 2.

[0157] It is also worth noting that in this embodiment, the connection between the bottom wall 12 and the side wall 11 is recessed inward toward the receiving cavity 3 to form an extension groove 41. Of course, in other embodiments, the connection between the bottom wall 12 and the side wall 11 may not have an extension groove 41.

[0158] Example 3

[0159] See Figure 19 Based on the above embodiment 1, the difference in this embodiment is that: the receiving groove 4 does not have an extension groove 41, but only a receiving groove 42, so as to facilitate the processing of the protective shell 1.

[0160] Furthermore, the connecting portion is configured as a channel 5 that penetrates the bottom wall 12 and the side wall 11. Of course, in other embodiments, the connecting portion may also be provided around the protective shell 1, or it may penetrate only the bottom wall 12 or only the side wall 11.

[0161] Furthermore, the center of the storage slot 42 coincides with the center of the receiving slot 4.

[0162] Example 4

[0163] Based on the above embodiment one, see Figures 20 to 23 The difference in this embodiment is that the receiving component 2 has the same structure as the protective shell 1, and the inner surface 111 of the receiving component 2 and the inner surface 111 of the protective shell 1 are arranged opposite to each other along the thickness direction of the protective shell 1 to form a receiving cavity 3 for accommodating the freeze-thaw bag 200. At this time, both the outer surface 112 of the receiving component 2 and the protective shell 1 are provided with receiving grooves 4, which can be used to store the tube assembly 100.

[0164] Furthermore, at this point, the latching part 8 includes a plate 81, a latch 82, and a locking member 84. Two plates 81 are provided, each connected to the protective shell 1 and the receiving member 2 respectively. Both plates 81 have latches 82. When the latches 82 on the two plates 81 overlap, the locking member 84 passes through both latches 82 to achieve a limiting connection between the receiving member 2 and the protective shell 1. The locking member 84 is configured as a combination of bolts and nuts.

[0165] It is worth noting that, at this time, the latching part 8 can be provided on all four sides of the protective shell 1.

[0166] Example 5

[0167] See Figure 2Based on the above as Embodiment 1, this embodiment also provides a freeze-thaw bag protection system, which has the freeze-thaw bag protection component and freeze-thaw bag 200 as described in Embodiment 1 above.

[0168] Example 6

[0169] See Figure 21 Based on the above embodiment two, this embodiment also provides a freeze-thaw bag protection system, which has the freeze-thaw bag protection component and freeze-thaw bag 200 as in embodiment two above.

[0170] The above embodiments are merely preferred embodiments of the present invention and should not be construed as limiting the scope of protection of the present invention. Any non-substantial changes and substitutions made by those skilled in the art based on the present invention shall fall within the scope of protection claimed by the present invention.

Claims

1. A freeze-thaw bag protection assembly for protecting a freeze-thaw bag connected to a tubular assembly; The freeze-thaw bag protection assembly includes a protective shell and a receiving component, wherein the protective shell and the receiving component cooperate to form a receiving cavity for accommodating the freeze-thaw bag, characterized in that... The protective shell and / or the receiving member have receiving grooves on their outer surfaces away from the receiving cavity for accommodating a portion of the pipe assembly; A connecting portion is provided between the receiving cavity and the receiving groove, so that the free end of the tube assembly can extend through the connecting portion to the receiving groove and be received.

2. The freeze-thaw bag protection assembly according to claim 1, characterized in that, The connecting portion is configured as a channel penetrating the protective shell; The channel is located on the protective shell corresponding to the tube assembly.

3. The freeze-thaw bag protection assembly according to claim 1, characterized in that, The receiving groove is formed by the protective shell recessing towards the receiving cavity, and the protective shell has side walls and bottom walls corresponding to the receiving groove; The projection of the bottom wall along the thickness direction of the protective shell at least covers the projection of the center of the freeze-thaw bag along the thickness direction of the protective shell; and / or, the side wall is provided with the connecting portion, and the connecting portion is configured as a channel penetrating the side wall, the channel being located on the protective shell corresponding to the tube assembly.

4. The freeze-thaw bag protection assembly according to claim 3, characterized in that, The receiving groove includes an extension groove; the extension groove is formed from the connection position of the side wall and the bottom wall towards the recess of the receiving cavity; the extension groove is distributed along the periphery of the receiving groove; And / or, The receiving groove includes a receiving groove formed by the bottom wall recessing towards the receiving cavity.

5. A freeze-thaw bag protection assembly according to claim 4, characterized in that, The channel is located within the extension groove, and there are multiple channels arranged at intervals within the extension groove; And / or, the bottom of the receiving slot is further away from the opening end of the receiving slot than the bottom of the extending slot; And / or, the bottom wall has a suppressing protrusion on its inner surface facing the receiving cavity; the suppressing protrusion is capable of abutting against the center of the freeze-thaw bag.

6. A freeze-thaw bag protection assembly according to claim 5, characterized in that, The protective shell has several hollow portions that are provided through it. Along the thickness direction of the protective shell, the projection of the hollow portion is located inside the projection of the extension groove and outside the projection of the suppression protrusion. And / or, The bottom wall includes several deformable portions, and the projections of the deformable portions are all located outside the projection of the suppressing convexity.

7. A freeze-thaw bag protection assembly according to any one of claims 4-6, characterized in that, The receiving groove is provided with a coiled column; a portion of the tube assembly can be wound around the coiled column.

8. A freeze-thaw bag protection assembly according to claim 7, characterized in that, At least two coiled tube columns are provided, and a tube clamping gap is formed between adjacent coiled tube columns. The tube clamping gap is used to allow partial passage of the tube assembly so that the tube assembly is wound around at least one of the coiled tube columns. And / or, The receiving groove includes a receiving groove, which is formed by the bottom wall recessing towards the receiving cavity, and the inner surface of the bottom wall corresponding to the position of the receiving groove has a corresponding suppressing protrusion; the coil column is disposed in the receiving groove; And / or, The projection of the boundary circle containing the outer perimeter of all the coils along the thickness direction of the protective shell covers the center of the freeze-thaw bag.

9. A freeze-thaw bag protection assembly according to any one of claims 3-6, characterized in that, The sidewall and the bottom wall are integrally formed.

10. A freeze-thaw bag protection assembly according to claim 1, characterized in that, It also includes a latching part, which connects the protective shell and the receiving part; The projection of the latching part along the thickness direction of the protective shell is located outside the projection of the receiving cavity along the thickness direction of the protective shell.

11. A freeze-thaw bag protection assembly according to claim 10, characterized in that, A reinforcing part is provided between the latching part and the receiving cavity.

12. The freeze-thaw bag protection assembly according to claim 1, characterized in that, The receiving component has the same structure as the protective shell, and the inner surface of the receiving component and the inner surface of the protective shell are arranged opposite to each other along the thickness direction of the protective shell to form a receiving cavity for accommodating the freeze-thaw bag. or, The receiving component has an inner side and an outer side, the inner side facing the freeze-thaw bag and arranged opposite to the inner surface of the protective shell along the thickness direction of the protective shell to form a receiving cavity for accommodating the freeze-thaw bag. The receiving part is provided on the inner side of the receiving component to receive the freeze-thaw bag.

13. A freeze-thaw bag protection assembly according to claim 12, characterized in that, The inner surface of the protective shell has a suppressing protrusion, and the inner side of the receiving component has a limiting protrusion; the center of the freeze-thaw bag is located between the suppressing protrusion and the limiting protrusion. And / or, The receiving component is provided with a peripheral portion around its circumference; The peripheral portion has a first wall surface and a second wall surface, the first wall surface being connected to the inner side surface of the receiving member, and the second wall surface being connected to the outer side surface of the receiving member; The first wall surface is provided with a first shape, and the second wall surface is provided with a second shape. When the first wall surface of one of the receiving components is disposed opposite to the second wall surface of the other receiving component, the first shape and the second shape are complementary.

14. A freeze-thaw bag protection system, characterized in that, The invention comprises a freeze-thaw bag protection assembly as described in any one of claims 1-13 and a freeze-thaw bag contained within the freeze-thaw bag protection assembly.

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