Biocompatible suspension electrode jet tube capable of realizing far-end discharge

Abstract

The invention relates to a biocompatible suspension electrode jet tube capable of realizing far-end discharge. The biocompatible suspension electrode jet tube comprises a dielectric tube, a PLA (polylactic acid) bracket, a ring electrode, a flexible tube and an induction conductor, according to the invention, far-end in-situ discharge in a deep tissue or a complex cavity is realized, and the limitation that discharge can only be carried out at a nozzle in the prior art is broken through; biocompatible materials (a PLA support and a silicone tube) are adopted, so that the safety and the adaptability in medical application are ensured; through the insulation coating and inductive coupling mode, the electrical safety of the device in the operation process is improved, and the common breakdown and electric shock problems in traditional long wire transmission are avoided. The device provided by the invention is high in flexibility, and can be widely applied to the scenes of skin sterilization, orifice inflammation diminishing, tumor ablation, medical instrument disinfection and the like.

Description

Technical Field

[0001] This invention relates to the field of medical device technology, and more specifically to a biocompatible suspended electrode jet tube for achieving remote discharge. Background Technology

[0002] Plasma discharge is a physical process that uses sufficient energy to ionize a neutral gas, generating plasma containing free electrons, positive ions, and neutral particles. In the medical and health field, it is used for skin surface sterilization, anti-inflammation, and promoting wound healing. The plasma is precisely sprayed onto skin lesions, such as diabetic foot, chronic ulcers, and burn wounds, via a distal flexible silicone tube. It can also be used for localized plasma therapy in cavities such as the bronchi, esophagus, nasal cavity, and rectum. It achieves minimally invasive, localized anti-tumor effects in deep tumors such as lung cancer and esophageal cancer. Distal plasma generators are used for the disinfection and treatment of periodontal disease, root canal infections, and oral mucosal lesions. In the field of disinfection and sterilization, distal plasma is used to disinfect the internal surfaces of medical devices such as endoscopes and catheters, avoiding high-temperature damage.

[0003] Traditional direct electrode discharge structures: Existing atmospheric pressure cryogenic plasma jet devices typically employ needle-shaped or ring-shaped electrodes directly positioned near the nozzle, generating plasma by exciting discharge through a high-voltage electric field within the gas channel. While this type of structure can achieve jet discharge, the electrodes are tightly coupled to the discharge region, preventing remote discharge. Furthermore, the high-voltage electrodes are directly exposed to the discharge region, posing a risk of electric shock and potential safety hazards to operators.

[0004] Dielectric barrier discharge (DBD) jet tubes: Some technologies use glass or ceramic tubes as the dielectric, with an external ring electrode and an internal gas passage forming a dielectric barrier discharge structure. The gas forms a plasma jet at the outlet. These devices are typically rigid structures, with the discharge location limited to the nozzle end. They lack flexibility and cannot penetrate into curved or narrow cavities for remote processing.

[0005] Conductor structures for long-distance potential transmission: Some technologies attempt to use extended conductors to transmit high-voltage electric fields to distant locations, achieving discharge relatively far from the power source. However, most of these devices use bare metal wires or simple insulation layers for protection, with the conductors directly coupled to the discharge area, posing risks of leakage, breakdown, and potential damage to biological tissues. Furthermore, inadequate conductor fixation methods make them prone to positional shifts or conductor deformation during long-distance transmission, leading to unstable discharge.

[0006] This shows that existing technologies still have significant shortcomings in ensuring biocompatibility, achieving stable remote plasma discharge, and improving clinical safety. Summary of the Invention

[0007] The purpose of this invention is to provide a biocompatible suspended electrode jet tube for achieving remote discharge, comprising: a dielectric tube, a PLA scaffold, a ring electrode, a flexible tube, and an inductive conductor.

[0008] The dielectric tube is a hollow columnar structure, with one end connected to an external gas generating device and the other end connected to a flexible tube, forming a gas jet channel.

[0009] The PLA bracket is installed inside the dielectric tube to fix the inductive conductor.

[0010] The sensing conductor extends from inside the dielectric tube to the end of the flexible tube, and the surface of the sensing conductor is covered with an insulating layer.

[0011] The ring electrode surrounds the outer wall of the dielectric tube.

[0012] The ring electrode is electrically connected to an external pulse generator.

[0013] The flexible tube is made of a biocompatible material.

[0014] When performing remote discharge using the jet tube, the end of the flexible tube is placed in front of the object to be sprayed. An external gas generating device inputs working gas, and an external pulse generator generates an electrical signal on the ring electrode, which in turn generates electromagnetic induction coupling with the induction conductor. The induction conductor generates an induced potential at the end of the flexible tube. The working gas undergoes primary ionization in the dielectric tube and secondary ionization as it flows through the end of the flexible tube, generating a plasma jet that acts on the object to be sprayed.

[0015] Furthermore, the dielectric tube is made of materials including quartz, borosilicate glass, alumina ceramic, and high-silicon glass.

[0016] The biocompatible materials include silicone and polytetrafluoroethylene.

[0017] Furthermore, a gas flow meter is also provided between the external gas generating device and the dielectric tube.

[0018] The gas flow meter is used to control the input flow rate and ratio of the working gas.

[0019] The input flow rate of the working gas is in the range of 0.5L / min to 10L / min.

[0020] The gas flow meter includes a gas mass flow controller and a flow-limiting orifice plate.

[0021] Furthermore, the insulating layer is made of a material including polyesterimide.

[0022] Furthermore, the external pulse generator includes a pulse power supply and a medium-frequency AC power supply.

[0023] The electrical signal generated on the ring electrode by the external pulse generator includes a square wave pulse voltage.

[0024] Furthermore, the square wave pulse voltage has a voltage amplitude range of 6KV-9kV, a pulse width range of 200 ns-2000ns, and a frequency range of 5kHz-10kHz.

[0025] Furthermore, the sensing conductor includes a suspended metal wire electrode and a hollow needle electrode.

[0026] The material used for the inductive conductor includes copper.

[0027] Furthermore, the length of the flexible tube ranges from 0 to 2 meters.

[0028] Furthermore, the working gas includes at least one of helium, argon, nitrogen, and oxygen.

[0029] Furthermore, the PLA bracket is manufactured using 3D printing.

[0030] The technical advantages of this invention are undeniable. It achieves in-situ discharge at the distal end within deep tissues or complex cavities, overcoming the limitation of existing technologies that can only discharge at the nozzle. The use of biocompatible materials (PLA scaffold, silicone tubing) ensures safety and compatibility in medical applications. Through insulation coating and inductive coupling, the electrical safety during device operation is improved, avoiding the breakdown and electric shock problems common in traditional long-wire transmission. The device provided by this invention is highly flexible and can be widely applied in scenarios such as skin sterilization, cavity anti-inflammatory treatment, tumor ablation, and medical device disinfection.

[0031] The beneficial effects of this invention include:

[0032] 1. Remote discharge capability: By placing an insulated copper wire inside the glass tube and extending it to the end of the silicone tube, combined with inductive coupling via a ring electrode, plasma discharge can be directly generated at a remote end. Compared with existing devices that can only discharge at the nozzle, this invention overcomes the problem of limited discharge location and can flexibly act on deep tissues and complex cavities.

[0033] 2. High safety: The copper wire is completely covered with a polyesterimide insulation layer, preventing direct contact with the patient and avoiding the risk of electric shock and breakdown during high-voltage conduction. Compared with traditional bare electrodes or simple insulated wires, this invention is safer in clinical applications.

[0034] 3. Good biocompatibility: The device uses a PLA scaffold and medical-grade silicone tubing, which has good flexibility and biocompatibility. It can be safely inserted into the patient's cavity or adhere to the skin tissue, significantly reducing the risk of tissue damage and rejection.

[0035] 4. Flexibility and adaptability: The flexible silicone tube can be up to 2 meters long and can be bent to fit the shape of the cavity, facilitating precise discharge in narrow or curved areas. Compared to rigid glass or ceramic tubes, this invention is more suitable for complex environments.

[0036] 5. Controllable treatment effect: By adjusting the input gas flow rate and high-pressure pulse parameters, the length, intensity and concentration of active substances of the plasma jet can be flexibly controlled to achieve personalized treatment for different tissues or diseases.

[0037] 6. Multi-scenario application: It can be used not only for superficial treatments such as skin sterilization and wound repair, but also for anti-tumor and anti-infection treatments in deep cavities such as the respiratory and digestive tracts. It also has extended applications such as disinfection of the inner wall of medical devices and surface modification of materials, making it widely applicable. Attached Figure Description

[0038] Figure 1 This is a schematic diagram showing the composition of each module of the present invention;

[0039] Figure 2 This is a schematic diagram of the plasma control delivery system in this invention;

[0040] Figure 3 This is a schematic diagram of the discharge system of the present invention;

[0041] Figure 4 This is a flowchart of the workflow of the present invention;

[0042] Figure 5 A schematic diagram of plasma generation at a remote location;

[0043] Figure 6 A schematic diagram showing the applied voltage and the measured voltage of the floating electrode; Figure 6 (a) is a schematic diagram of the applied voltage; Figure 6 (b) is a schematic diagram of the measured voltage of the suspended electrode;

[0044] In the diagram: 1. Dielectric tube; 2. PLA support; 3. Ring electrode; 4. Flexible tube; 5. Induction conductor; 6. Plasma jet; 7. External gas generating device; 8. Gas flow meter; 9. External pulse generator. Detailed Implementation

[0045] The present invention will be further described below with reference to embodiments, but it should not be construed that the scope of the present invention is limited to the following embodiments. Various substitutions and modifications made based on ordinary technical knowledge and common practices in the art without departing from the above-described technical concept of the present invention should be included within the scope of protection of the present invention.

[0046] Example 1:

[0047] See Figures 1 to 6A biocompatible suspended electrode jet tube for achieving remote discharge includes: a dielectric tube 1, a PLA support 2, a ring electrode 3, a flexible tube 4, and an inductive conductor 5.

[0048] The dielectric tube 1 is a hollow columnar structure, with one end connected to the external gas generating device 7 and the other end connected to the flexible tube 4, forming a gas jet channel.

[0049] The PLA bracket 2 is installed inside the dielectric tube 1 and is used to fix the induction conductor 5.

[0050] The inductive conductor 5 extends from inside the dielectric tube 1 to the end of the flexible tube 4, and the surface of the inductive conductor 5 is covered with an insulating layer.

[0051] The ring electrode 3 is surrounded on the outer wall of the dielectric tube 1.

[0052] The ring electrode 3 is electrically connected to the external pulse generator 9.

[0053] The flexible tube 4 is made of a biocompatible material.

[0054] When performing remote discharge using the jet tube, the end of the flexible tube 4 is placed in front of the object to be sprayed. The external gas generating device 7 inputs working gas, and the external pulse generator 9 generates an electrical signal on the ring electrode 3, which in turn generates electromagnetic induction coupling with the induction conductor 5. The induction conductor 5 generates an induced potential at the end of the flexible tube 4. The working gas undergoes primary ionization in the dielectric tube 1 and secondary ionization as it flows through the end of the flexible tube 4, generating a plasma jet 6, which acts on the object to be sprayed.

[0055] Example 2:

[0056] A biocompatible suspended electrode jet tube for achieving remote discharge is described in Example 1. Further, the dielectric tube 1 is made of materials including quartz, borosilicate glass, alumina ceramic, and high-silicon glass.

[0057] The biocompatible materials include silicone and polytetrafluoroethylene.

[0058] Example 3:

[0059] A biocompatible suspended electrode jet tube for achieving remote discharge, the main technical contents of which are described in any one of Embodiments 1 to 2, further wherein a gas flow meter 8 is provided between the external gas generating device 7 and the dielectric tube 1.

[0060] The gas flow meter 8 is used to control the input flow rate and ratio of the working gas.

[0061] The input flow rate of the working gas is in the range of 0.5L / min to 10L / min.

[0062] The gas flow meter 8 includes a gas mass flow controller and a flow-limiting orifice plate.

[0063] Example 4:

[0064] A biocompatible suspended electrode jet tube for achieving remote discharge, the main technical contents of which are described in any one of Examples 1 to 3, and further, the insulating layer is made of polyesterimide.

[0065] Example 5:

[0066] A biocompatible suspended electrode jet tube for achieving remote discharge, the main technical contents of which are described in any one of Embodiments 1 to 4. Further, the external pulse generator 9 includes a pulse power supply and a medium-frequency AC power supply.

[0067] The electrical signal generated on the ring electrode 3 by the external pulse generator 9 includes a square wave pulse voltage.

[0068] Example 6:

[0069] A biocompatible suspended electrode jet tube for achieving remote discharge, the main technical contents of which are described in any one of Examples 1 to 5. Further, the voltage amplitude range of the square wave pulse voltage is 6KV-9kV, the pulse width range is 200 ns-2000ns, and the frequency range is 5kHz-10kHz.

[0070] Example 7:

[0071] A biocompatible suspended electrode jet tube for achieving remote discharge, the main technical contents of which are described in any one of Examples 1 to 6, further wherein the inductive conductor 5 includes a suspended metal wire electrode and a hollow needle electrode.

[0072] The material used for the inductive conductor 5 includes copper.

[0073] Example 8:

[0074] A biocompatible suspended electrode jet tube for achieving remote discharge, the main technical contents of which are described in any one of Examples 1 to 7, and further, the length of the flexible tube 4 is in the range of 0-2m.

[0075] Example 9:

[0076] A biocompatible suspended electrode jet tube for achieving remote discharge, the main technical contents of which are described in any one of Examples 1 to 8, further wherein the working gas includes at least one of helium, argon, nitrogen and oxygen.

[0077] Example 10:

[0078] A biocompatible suspended electrode jet tube for achieving remote discharge, the main technical contents of which are described in any one of Examples 1 to 9, and further, the PLA scaffold 2 is made by 3D printing.

[0079] Example 11:

[0080] See Figures 1 to 6 A biocompatible suspended electrode jet tube for achieving remote discharge includes: a dielectric tube 1, a PLA support 2, a ring electrode 3, a flexible tube 4, and an inductive conductor 5.

[0081] The dielectric tube 1 is a hollow columnar structure, with one end connected to the external gas generating device 7 and the other end connected to the flexible tube 4, forming a gas jet channel.

[0082] The PLA bracket 2 is installed inside the dielectric tube 1 and is used to fix the induction conductor 5.

[0083] The inductive conductor 5 extends from inside the dielectric tube 1 to the end of the flexible tube 4, and the surface of the inductive conductor 5 is covered with an insulating layer to prevent electric shock and leakage current.

[0084] The ring electrode 3 is surrounded on the outer wall of the dielectric tube 1.

[0085] The ring electrode 3 is electrically connected to the external pulse generator 9.

[0086] The flexible tube 4 is made of a biocompatible material.

[0087] When performing remote discharge using the jet tube, the end of the flexible tube 4 is placed in front of the object to be sprayed. The external gas generating device 7 inputs working gas, and the external pulse generator 9 generates an electrical signal on the ring electrode 3, which in turn generates electromagnetic induction coupling with the induction conductor 5. The induction conductor 5 generates an induced potential at the end of the flexible tube 4. The working gas undergoes primary ionization in the dielectric tube 1 and secondary ionization as it flows through the end of the flexible tube 4, generating a plasma jet 6, which acts on the object to be sprayed.

[0088] The targets to be sprayed include the skin surface, the inside of cavities (such as the bronchus, esophagus, nasal cavity, and rectum), deep tumors, and oral mucosa.

[0089] Because the copper wire is entirely covered by a polyesterimide insulation layer, the human body will not come into direct contact with the high voltage during operation, ensuring safety. This structure achieves separation of "near-end power supply - far-end discharge," allowing plasma to be stably generated at the end of a flexible silicone tube several meters away from the power source. During operation, the length of the plasma jet, the concentration of active material, and the effective range can be precisely controlled by adjusting the input gas flow rate and high-voltage pulse parameters.

[0090] Example 12:

[0091] A biocompatible suspended electrode jet tube for achieving remote discharge is described in Example 11. Further, the dielectric tube 1 is made of materials including quartz, borosilicate glass, alumina ceramic, high-silicon glass, or other materials with good thermal and dimensional stability.

[0092] The biocompatible materials include silicone and polytetrafluoroethylene.

[0093] Example 13:

[0094] A biocompatible suspended electrode jet tube for achieving remote discharge is described in any one of Embodiments 11 to 12. Furthermore, a gas flow meter 8 is provided between the external gas generating device 7 and the dielectric tube 1.

[0095] The gas flow meter 8 is used to control the input flow rate and ratio of the working gas.

[0096] The input flow rate of the working gas is in the range of 0.5L / min to 10L / min.

[0097] The gas flow meter 8 includes a gas mass flow controller and a flow-limiting orifice plate.

[0098] Example 14:

[0099] A biocompatible suspended electrode jet tube for achieving remote discharge, the main technical contents of which are described in any one of Examples 11 to 13, and further, the insulating layer is made of polyesterimide.

[0100] Example 15:

[0101] A biocompatible suspended electrode jet tube for achieving remote discharge, the main technical contents of which are described in any one of Embodiments 11 to 14. Further, the external pulse generator 9 includes a pulse power supply and a medium-frequency AC power supply.

[0102] The electrical signal generated on the ring electrode 3 by the external pulse generator 9 includes a square wave pulse voltage.

[0103] Example 16:

[0104] A biocompatible suspended electrode jet tube for achieving remote discharge, the main technical contents of which are described in any one of Examples 11 to 15. Further, the voltage amplitude range of the square wave pulse voltage is 6KV-9kV, the pulse width range is 200 ns-2000ns, and the frequency range is 5kHz-10kHz.

[0105] Example 17:

[0106] A biocompatible suspended electrode jet tube for achieving remote discharge, the main technical contents of which are described in any one of Examples 11 to 16, further wherein the inductive conductor 5 includes a suspended metal wire electrode and a hollow needle electrode.

[0107] The material used for the inductive conductor 5 includes copper.

[0108] Example 18:

[0109] A biocompatible suspended electrode jet tube for achieving remote discharge is described in any one of Examples 11 to 17. Furthermore, the length of the flexible tube 4 ranges from 0 to 2 meters. This allows for deep penetration into cavities or narrow spaces, ensuring flexible operation.

[0110] Example 19:

[0111] A biocompatible suspended electrode jet tube for achieving remote discharge, the main technical contents of which are described in any one of Examples 11 to 18, further wherein the working gas includes at least one of helium, argon, nitrogen and oxygen.

[0112] Example 20:

[0113] A biocompatible suspended electrode jet tube for achieving remote discharge, the main technical contents of which are described in any one of Examples 11 to 19, and further, the PLA scaffold 2 is made by 3D printing.

[0114] Example 21:

[0115] See Figures 1 to 6 A biocompatible suspended electrode jet tube for achieving remote discharge, the main contents of which include:

[0116] Structural composition:

[0117] 1. Glass tube discharge unit

[0118] The glass tube serves as the main channel, with annular electrodes wrapped around its outer wall. These electrodes are connected to a high-voltage power supply. One end of the glass tube has a gas inlet, and the other end is connected to a silicone tube to form a gas jet channel.

[0119] 2. Flexible transfer silicone tube

[0120] Utilizing biocompatible and flexible medical-grade silicone tubing, it can reach lengths of up to 2 meters. Attached to the end of a glass tube, it can be inserted deep into cavities or narrow spaces, ensuring flexible operation.

[0121] 3. Internal conductive transmission unit

[0122] A 3D-printed PLA support is placed inside a glass tube to support and secure a copper wire conductor. The copper wire extends from inside the glass tube to the entire length of the silicone tube, down to the end of the silicone tube. The surface of the copper wire is coated with a polyesterimide insulating layer to prevent electric shock and leakage current.

[0123] 4. Power supply and sensing unit

[0124] The external ring electrode is connected to a high-voltage power supply, which can output a square wave pulse voltage of approximately 7000 V. The copper wire itself is not directly connected to the power supply, but rather an induced potential of approximately 2000 V is generated at the end of the copper wire through electromagnetic induction between the ring electrode and the copper wire.

[0125] Working principle and working method:

[0126] A high-voltage square-wave pulse is applied to the ring electrode on the outer wall of the glass tube, inducing electromagnetic coupling between the glass tube and the internal insulating copper wire. The copper wire induces a potential of approximately 2000 V at the distal end of the silicone tube, which, in conjunction with the gas jet, generates a stable plasma discharge at the distal outlet. Because the copper wire is entirely covered by a polyesterimide insulation layer, the human body will not come into direct contact with the high voltage during operation, ensuring safety. This structure achieves separation of "near-end power supply—far-end discharge," allowing plasma to be stably generated at the end of the flexible silicone tube, several meters away from the power source. During operation, the length of the plasma jet, the concentration of active material, and the effective range can be precisely controlled by adjusting the input gas flow rate and high-voltage pulse parameters.

[0127] Example 22:

[0128] See Figures 1 to 6 A biocompatible suspended electrode jet tube for achieving remote discharge, the main contents of which include:

[0129] Please see the appendix Figure 1 A biocompatible suspended electrode jet tube includes the following components:

[0130] Dielectric tube 1: The tube wall thickness is about 1.5 mm. It has good dielectric properties and mechanical strength, and can maintain stable discharge characteristics without easily breaking.

[0131] PLA bracket 2: Made by 3D printing, it is used to fix the suspended metal wire electrode inside the dielectric tube to ensure the stability of the electrode position.

[0132] High voltage electrode 3: Located in a ring position outside the dielectric tube, used to connect to an external high voltage power supply.

[0133] Silicone Tube 4: Utilizing biocompatible medical-grade silicone tubing with a wall thickness of approximately 1 mm, this tubing combines flexibility and insulation properties to effectively avoid the risk of electric shock. Furthermore, the silicone tubing can reach lengths of up to 2 m, allowing it to penetrate deep into natural body cavities (such as the bronchi) for distal treatment.

[0134] Suspended copper wire electrode 5: Extends along the inside of the dielectric tube and silicone tube, and the outer surface of the copper wire is covered with a polyesterimide insulating layer to prevent electric shock and leakage current.

[0135] Through the above structure, the device achieves the functions of applying voltage at the near end and safely discharging at the far end.

[0136] Please see the appendix Figure 2 The control and delivery system of this invention includes: a working gas source, a gas flow meter, and a pulsed high-voltage generator. The working gas may include at least one of helium, argon, nitrogen, and oxygen. One or more working gases flow through a mass flow controller (MFC), which controls the ratio of rare gas doping with oxygen and nitrogen, as well as the flow rate of the mixed working gas. A high-precision MFC can control the mixed gas flow rate within the range of 0.5 L / min to 10 L / min, with the oxygen and nitrogen doping ratio typically set to 1000 ppm. The mixed working gas is connected to a suspended electrode via a quick-connect interface. The input working gas is ionized by a square wave pulse with a voltage amplitude range of 6 kV-9 kV, a pulse width of 200-2000 ns, and a frequency range of 5 kHz-10 kHz. It undergoes primary ionization within a dielectric tube and secondary ionization at the end of the silicone tube of the suspended electrode before being discharged.

[0137] Figure 3 The invention demonstrates the composition of a treatment system comprising a voltage input module, a gas control module, a flow input module, and a feedback adjustment module. By precisely controlling the gas flux, a mixed working gas is introduced into the system to ensure that the plasma delivery medium environment has an appropriate gas composition and concentration. A multi-parameter adjustable high-voltage generator ionizes and generates a high concentration of active substances. Through precise control of the gas flux and discharge parameters, the system ensures the stability and controllability of the plasma jet at the distal end, thereby guaranteeing therapeutic efficacy.

[0138] Figure 4 The workflow of this invention is demonstrated.

[0139] Input the applied voltage and gas flow rate at the human-machine interface; the working gas is mixed by the gas control device and adjusted to the set flow rate by the flow module; a pulsed high voltage is applied to the external electrode, generating primary ionization in the dielectric tube; the voltage is induced on the suspended copper wire through induction, inducing secondary discharge at the outlet of the distal silicone tube; the formed plasma jet acts on the target tissue or model to achieve the predetermined treatment or treatment effect.

[0140] Figure 5 This diagram illustrates the remote plasma generation. A high-voltage square wave pulse of 7000V-1us-10kHz is applied, along with helium gas at a flow rate of 4L / min. The plasma is generated in a human lung model 2m away.

[0141] Figure 6 Under the condition of applying a high-voltage square wave pulse of 8000 V, 1 μs pulse width, and 10 kHz frequency, with a helium flow rate of 4 L / min, the measured peak voltage at the end of the suspended electrode was 2.4 kV. This voltage amplitude, with the insulation of the silicone tube, will not cause an electric shock, verifying the safety and effectiveness of the device of the present invention under long-distance transmission conditions.

[0142] Example 23:

[0143] A biocompatible suspended electrode jet tube for achieving remote discharge, the main technical contents of which are described in Example 22, further simplifies the gas type: the original multi-component working gas (such as helium / argon mixed with oxygen or nitrogen) is simplified to a single helium. Sufficient active ingredients can be generated by adjusting the voltage amplitude, thereby reducing the complexity of gas source configuration and lowering operating costs.

[0144] Example 24:

[0145] A biocompatible suspended electrode jet tube for achieving remote discharge is described in any one of Examples 22 to 23. Further, the discharge electrode is replaced by a hollow needle electrode instead of a suspended metal wire electrode. This still forms a secondary ionization region and generates plasma at the remote end, further simplifying the electrode structure and processing technology.

[0146] Example 25:

[0147] A biocompatible suspended electrode jet tube for achieving remote discharge, the main technical contents of which are described in any one of Examples 22 to 24. Furthermore, the gas delivery method is simplified: the independent gas mass flow controller (MFC) is replaced with a flow-limiting orifice plate with a fixed flow rate to achieve constant gas flow rate output. Although it lacks fine control function, it can meet the needs of routine treatment, reduce equipment cost and improve system stability.

[0148] Example 26:

[0149] A biocompatible suspended electrode jet tube for achieving remote discharge, the main technical contents of which are described in any one of Examples 22 to 25. Further, the power supply module is replaced: the high-voltage pulse power supply is replaced with a medium-frequency AC power supply. After optimizing the frequency range (10–20 kHz), it can still generate a sufficient concentration of active species, while reducing the complexity of the pulse control circuit.

[0150] Example 27:

[0151] A biocompatible suspended electrode jet tube for achieving remote discharge is described in any one of Examples 22 to 26. Furthermore, the delivery device is optimized by replacing the original silicone tube with a medical-grade polytetrafluoroethylene (PTFE) tube, which has better corrosion resistance and insulation properties, thereby further improving the safety and lifespan of the device.

[0152] Example 28:

[0153] A biocompatible suspended electrode jet tube for remote discharge is described in any one of Examples 22 to 27. Furthermore, the terminal interface is simplified: the complex human-machine interface is removed, and basic control of voltage and flow is achieved only through knobs and indicator lights, making the device easier to carry and operate.

Claims

1. A biocompatible suspended electrode jet tube for achieving remote discharge, characterized in that, include: Dielectric tube (1), PLA support (2), ring electrode (3), flexible tube (4), inductive conductor (5); The dielectric tube (1) is a hollow columnar structure, with one end connected to an external gas generating device (7) and the other end connected to a flexible tube (4) to form a gas jet channel. The PLA bracket (2) is installed inside the dielectric tube (1) to fix the inductive conductor (5); The inductive conductor (5) extends from inside the dielectric tube (1) to the end of the flexible tube (4), and the surface of the inductive conductor (5) is covered with an insulating layer; The ring electrode (3) surrounds the outer wall of the dielectric tube (1); The ring electrode (3) is electrically connected to the external pulse generator (9); The flexible tube (4) is made of a biocompatible material; When performing remote discharge using the jet tube, the end of the flexible tube (4) is placed in front of the object to be sprayed. The external gas generating device (7) inputs working gas, and the external pulse generator (9) generates an electrical signal on the ring electrode (3), which in turn generates electromagnetic induction coupling with the induction conductor (5). The induction conductor (5) generates an induced potential at the end of the flexible tube (4). The working gas is ionized once in the dielectric tube (1) and ionized a second time as it flows through the end of the flexible tube (4), generating a plasma jet (6) that acts on the object to be sprayed.

2. The biocompatible suspended electrode jet tube for achieving remote discharge according to claim 1, characterized in that, The dielectric tube (1) is made of materials including quartz, borosilicate glass, alumina ceramic, and high-silicon glass; The biocompatible materials include silicone and polytetrafluoroethylene.

3. The biocompatible suspended electrode jet tube for achieving remote discharge according to claim 1, characterized in that, A gas flow meter (8) is also provided between the external gas generating device (7) and the dielectric tube (1); The gas flow meter (8) is used to control the input flow rate and ratio of the working gas; The input flow rate of the working gas is in the range of 0.5L / min-10L / min; The gas flow meter (8) includes a gas mass flow controller and a flow-limiting orifice plate.

4. The biocompatible suspended electrode jet tube for achieving remote discharge according to claim 1, characterized in that, The insulating layer is made of polyesterimide.

5. A biocompatible suspended electrode jet tube for achieving remote discharge according to claim 1, characterized in that, The external pulse generator (9) includes a pulse power supply and a medium-frequency AC power supply; The electrical signal generated by the external pulse generator (9) on the ring electrode (3) includes a square wave pulse voltage.

6. A biocompatible suspended electrode jet tube for achieving remote discharge according to claim 5, characterized in that, The square wave pulse voltage has an amplitude range of 6kV-9kV, a pulse width range of 200ns-2000ns, and a frequency range of 5kHz-10kHz.

7. A biocompatible suspended electrode jet tube for achieving remote discharge according to claim 1, characterized in that, The inductive conductor (5) includes a suspended metal wire electrode and a hollow needle electrode; The material used for the inductive conductor (5) includes copper.

8. A biocompatible suspended electrode jet tube for achieving remote discharge according to claim 1, characterized in that, The length of the flexible tube (4) ranges from 0 to 2 m.

9. A biocompatible suspended electrode jet tube for achieving remote discharge according to claim 1, characterized in that, The working gas includes at least one of helium, argon, nitrogen, and oxygen.

10. A biocompatible suspended electrode jet tube for achieving remote discharge according to claim 1, characterized in that, The PLA bracket (2) is manufactured by 3D printing.

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