POCT (Point of Care Testing) microfluidic detection device

Abstract

The invention discloses a POCT microfluidic detection device which structurally comprises a reaction device, a machine cover, a sliding rail, an adjusting frame, a processing device, a placement groove, a placement plate and a main body. The main body is arranged at a corresponding use position, a material for sampling is placed on the placement plate, the reaction device is mounted in the placement groove in a matched manner, and the reaction device is arranged in the placement groove in a matched manner; the adjusting frame moves left and right under the action of the sliding rail to adjust the position of the processing device, the processing device can be vertically arranged on the reaction device through cooperation of the adjusting frame and the processing device, sampling is carried out through the processing device, and therefore a sample can be vertically injected into the reaction device, and the reaction device is installed in the containing groove in a matched mode. The reaction device is protected through the movement of the machine cover and the placing groove through the hinge, so that the reaction device is not interfered by the outside in a sample detection process, and the detection efficiency of the reaction device is ensured.

Description

Technical Field

[0001] This invention relates to the field of medical device technology, specifically to a POCT microfluidic detection device. Background Technology

[0002] Point-of-care testing (POCT) is a system for rapid testing of human blood. POCT scanners are primarily used in emergency departments of major hospitals and for timely testing in primary care facilities, providing faster biochemical results. In vitro diagnostics (IVD) refers to obtaining relevant clinical diagnostic information by testing samples from the body, including blood, body fluids, and tissues, outside the human body, thereby helping to determine diseases or bodily functions. Currently, IVD technology with significant development potential and rapid growth focuses on molecular diagnostics and point-of-care testing, primarily based on nucleic acid detection. Areas for improvement when using POCT microfluidic testing devices include: When using a POCT microfluidic testing device, under normal circumstances, it is equipped with rotating rod one, rotating rod two, rotating block, and support block. Rotating the rotating plate allows the support blocks on both sides to rotate. The rotating block and fixed block, along with the rotating support block, support the front and rear sides of the base, increasing its stability. The load-bearing blocks on the left and right sides further enhance the overall stability of the portable POCT testing instrument on the base. During use, the sampling needle moves inside different reaction tubes, coming into contact with different test liquids. This causes the residual liquids on the outer wall of the sampling needle to mix, leading to cross-contamination and inaccurate test results. Furthermore, when the sampling needle removes the test liquid after placing it into the reaction tube, the residual liquid on its outer wall accumulates at the bottom of the reaction tube due to gravity, forming droplets that fall onto the tray. This results in the tray containing residual test liquids, leading to bacterial contamination and affecting the accuracy of the device's testing. Summary of the Invention

[0003] To address the shortcomings of existing technologies, this invention provides the following technical solution: a POCT microfluidic detection device, comprising a reaction device, a cover, a slide rail, an adjustment frame, a processing device, a placement slot, a placement plate, and a main body. The reaction device is mounted on the placement slot, which is embedded inside the main body. The placement slot has a cover, which is connected to the placement slot via a hinge. The upper end of the placement slot faces the processing device, and the upper end of the processing device is vertically inserted into the adjustment frame. The lower end of the adjustment frame is mounted on the slide rail, and the adjustment frame slides on the slide rail. The slide rail is fixed to the main body, and the main body has a placement plate connected to it.

[0004] As a further optimization of the invention, the processing device includes a disinfection component, a linkage, a locking rod, a movable tube, a locking ring, and a sampler. The sampler is internally connected to the disinfection component, and a locking ring is fitted to the upper end of the disinfection component. Four equally spaced, circularly arranged locking rods are inserted into the locking ring, and the four locking rods are fixedly connected to the outer wall of the movable tube. The lower end of the movable tube is provided with a linkage, and the upper end of the linkage is movably connected to the inside of the movable tube. The end of the linkage away from the movable tube extends into the interior of the disinfection component and connects to the sampler.

[0005] As a further optimization of the invention, the disinfection component includes a sponge pad, a squeezing block, a limiting fastener, an outer frame, an ultraviolet light strip, a connecting cavity, a mounting pusher, and a pull rod. Two sponge pads are provided, and the two sponge pads are fitted together on the inner sides of the two squeezing blocks. A pull rod is inserted into one end of the squeezing block away from the sponge pad, and the other end of the pull rod extends through the outer frame. Mounting pushers are symmetrically installed on both sides of the inner side of the outer frame, and ultraviolet light strips are provided on the inner sides of both mounting pushers. The end of the ultraviolet light strip away from the mounting pusher is attached to both sides of the connecting cavity, and sponge pads are connected to both sides of the lower end of the connecting cavity. The sponge pads and the ultraviolet light strip are aligned on the same straight line.

[0006] As a further optimization of the invention, the reaction device is fitted inside the placement slot. The cover, in conjunction with the placement slot, protects the reaction device. The sample is injected into the corresponding position inside the reaction device via the adjustment frame and the movement of the processing device. The movable tube on the processing device is fixedly inserted into the adjustment frame. The disinfection component is installed at the lower end of the movable tube via a locking rod and a locking ring. The linkage extends through the disinfection component and connects with the sampler, thereby driving the sampler to move up and down in the connecting cavity inside the disinfection component. The sponge pads on the left and right sides of the connecting cavity are pressed against the sides of the sampler by the squeezing block and the pulling rod. The ultraviolet lamp strip is also connected to the sides of the sampler by the installation pusher, effectively disinfecting the sampler.

[0007] As a further optimization of the invention, the reaction device is installed inside the placement slot, and the adjustment frame moves left and right under the action of the slide rail to adjust the position of the processing device, so that the processing device can be vertically set on the reaction device and the sample can be vertically injected into the reaction device.

[0008] As a further optimization of the invention, the movable tube on the processing device is fixed on the adjustment frame, and the locking rod will assist the movable tube in being stably connected to the adjustment frame. The movable tube is kept on the same straight line as the disinfection component through the locking rod, so that the linkage can stably drive the sampler to move up and down inside the disinfection component for disinfection.

[0009] As a further optimization of the invention, the upper end of the outer frame is fitted with a retaining ring and a retaining rod, so that the linkage extends vertically through the outer frame into the connecting cavity and connects with the sampler. The sampler will then pass through the connecting cavity and connect with the sponge pad and the ultraviolet light strip through the connecting cavity.

[0010] As a further optimization of the invention, the reaction device includes a turntable, a support platform, a tray, a sample detection platform, and reaction components. The turntable is mounted on the support platform and is connected to the bottom of the tray through the support platform. The sample detection platform is fixedly connected to the upper end of the tray, and multiple reaction components are arranged in a ring at equal intervals on the sample detection platform. The reaction components are snapped together on the outer ring of the sample detection platform.

[0011] As a further optimization of the invention, the support platform is installed inside the placement slot, and the turntable drives the tray to rotate inside the placement slot, so that the sample detection stage will move accordingly, thereby allowing the position of the reaction component to be adjusted to be in opposition to the processing device for use.

[0012] As a further optimization of the invention, the reaction assembly includes a reaction tube, a barrier component, a connecting tube, and a fixing plate. The upper end of the reaction tube is fitted with the barrier component, and the lower end of the barrier component is provided with a fixing plate. The fixing plate is embedded in the upper end of the inner wall of the reaction tube, and the middle position of the fixing plate is provided with a connecting tube connected to it. The upper end of the connecting tube is connected to the barrier component.

[0013] As a further optimization of the invention, the reaction tube is externally fastened to the outer edge of the sample detection stage, so that the reaction tube can be stably placed on the tray for rotation via the sample detection stage.

[0014] As a further optimization of the invention, the blocking component includes a connecting plate, a holding connector, a slide rail, and a swing plate. The connecting plate has five slide rails connected to it, and each of the five slide rails is connected to a corresponding swing plate. The upper end of the swing plate is slidably connected to the slide rail, and the five swing plates simultaneously open and close on the holding connector through the slide rail. The holding connector is located in the middle of the connecting plate.

[0015] As a further optimization of the invention, the swing plate moves on the slide rail through the joint above it. When the five swing plates open at the same time, the insert connector is exposed. Conversely, when the five swing plates close at the same time, the insert connector effectively plays a sealing role.

[0016] As a further optimization of the invention, the insert connector is provided with an interface, an air bladder, a snap-fit ​​connector, a contact scraper, and a connector. The interface is located in the middle of the snap-fit ​​connector, and the snap-fit ​​connector is provided with multiple connectors arranged in a ring at equal intervals. Each of the multiple connectors is provided with an air bladder, and the end of the connector away from the snap-fit ​​connector is connected to a contact scraper. The multiple contact scrapers are connected by the connectors to form a ring structure on the outer ring of the interface.

[0017] As a further optimization of the invention, the interface is located in the middle of the connecting plate, and multiple contact scrapers are connected to the connector on the outer ring of the interface. Under the support of the airbag, the connector can move and adjust the contact scrapers inside the interface. Beneficial effects

[0018] The present invention provides a POCT microfluidic detection device, which has the following beneficial effects: 1. This invention places the main body in the corresponding usage position, places the sampling material on the placement plate, and then fits the reaction device into the placement slot. An adjusting frame moves left and right under the action of a slide rail to adjust the position of the processing device. Through the movement of the adjusting frame in conjunction with the processing device, the processing device can be vertically erected on the reaction device. The processing device then takes samples, allowing the samples to be vertically injected into the reaction device. The reaction device fits perfectly into the placement slot, and the cover and placement slot are hinged to protect the reaction device, ensuring that the reaction device is not affected by external interference during sample testing and guaranteeing the detection efficiency of the reaction device. 2. In this invention, the movable tube on the processing device is fixedly inserted into the adjusting frame with the assistance of four clamping rods. The lower end of the clamping ring installed at the lower end of the clamping rods fits into the top of the disinfection component, so that the movable tube can be kept in a straight line with the disinfection component through the cooperation of the clamping rods and the clamping ring. A linkage component is connected through the disinfection component and the movable tube. The linkage component extends into the two to make adjustments, and the lower end of the linkage component extends into the interior of the disinfection component to connect with the sampler. This allows the linkage component to stably drive the sampler to move up and down inside the disinfection component for disinfection. This makes it less likely for the sampler to be cross-contaminated when it is reused, thereby ensuring the accuracy of the test results.

[0019] 3. In this invention, the reaction device is stably installed inside the placement slot via a support platform. The turntable, driven by the support platform, rotates the tray inside the placement slot. Under the control of the main body, the turntable rotates at a uniform speed. The sample detection platform above it moves stably under the influence of the tray, allowing for adjustment of the position of the reaction components. This ensures the adjusted reaction components are used in a perpendicular position to the processing device. The reaction tubes on the reaction components are externally fastened to the outer edge of the sample detection platform, allowing the reaction tubes to be stably placed on the tray for rotation, thus ensuring the accuracy of the equipment's operation and testing. Attached Figure Description

[0020] Other features, objects, and advantages of the present invention will become more apparent from the following detailed description of non-limiting embodiments with reference to the accompanying drawings: Figure 1 This is a schematic diagram of a POCT microfluidic detection device. Figure 2 This is a schematic diagram of a three-dimensional structure of an improved processing device.

[0021] Figure 3 This is a cross-sectional structural diagram of an improved disinfection component.

[0022] Figure 4 This is a schematic diagram of a three-dimensional structure of an improved reaction device.

[0023] Figure 5 This is a schematic diagram of the cross-sectional structure of an improved reaction component.

[0024] Figure 6 This is a top view schematic diagram of an improved barrier component.

[0025] Figure 7 This is a schematic diagram of the internal structure of an improved insert connector.

[0026] In the diagram: reaction device-1, machine cover-2, slide rail-3, adjustment frame-4, processing device-5, placement tank-6, placement plate-7, main body-8.

[0027] Disinfection components-51, linkage components-52, clamping rod-53, movable tube-54, retaining ring-55, sampler-56.

[0028] 511. Sponge pad, 512. Extrusion block, 513. Limit fastener, 514. Outer frame, 515. Ultraviolet light strip, 516. Connecting cavity, 517. Mounting pusher, 518. Pull rod.

[0029] Turntable-11, Support platform-12, Tray-13, Sample testing platform-14, Reaction assembly-15.

[0030] Reaction tube-151, barrier assembly-152, connecting tube-153, fixing plate-154.

[0031] Connecting plate-1521, insert connector-1522, slide rail-1523, swing plate-1524.

[0032] Interface-5221, airbag-5222, snap-fit-5223, contact scraper-5224, connector-5225. Detailed Implementation

[0033] To make the technical means, creative features, objectives and effects of this invention easier to understand, the invention will be further described below in conjunction with specific embodiments.

[0034] Example 1 Please see Figures 1-3 , This invention provides a POCT microfluidic detection device. A POCT microfluidic detection device includes a reaction device 1, a cover 2, a slide rail 3, an adjustment frame 4, a processing device 5, a placement slot 6, a placement plate 7, and a main body 8. The reaction device 1 is mounted on the placement slot 6, which is embedded inside the main body 8. The cover 2 is provided on the placement slot 6 and is connected to the placement slot 6 by a hinge. The upper end of the placement slot 6 faces the processing device 5, and the upper end of the processing device 5 is vertically inserted into the adjustment frame 4. The lower end of the adjustment frame 4 is provided on the slide rail 3 and is slidably connected to the slide rail 3. The slide rail 3 is fixed to the main body 8, and the main body 8 is provided with a placement plate 7 connected to it.

[0035] The processing device 5 is provided with a disinfection component 51, a linkage 52, a locking rod 53, a movable tube 54, a retaining ring 55, and a sampler 56. The sampler 56 is connected through the inside of the disinfection component 51, and the upper end of the disinfection component 51 is fitted with a retaining ring 55. Four equally spaced ring-shaped locking rods 53 are inserted into the retaining ring 55, and the four locking rods 53 are fixedly connected to the outer wall of the movable tube 54. The lower end of the movable tube 54 is provided with a linkage 52, and the upper end of the linkage 52 is movably connected to the inside of the movable tube 54. The end of the linkage 52 away from the movable tube 54 extends through the inside of the disinfection component 51 and is connected to the sampler 56.

[0036] The disinfection component 51 includes a sponge pad 511, a squeezing block 512, a limiting fastener 513, an outer frame 514, an ultraviolet light strip 515, a connecting cavity 516, a mounting pusher 517, and a pull rod 518. Two sponge pads 511 are provided, and the two sponge pads 511 are fitted together on the inner sides of the two squeezing blocks 512. A pull rod 518 is inserted into one end of each squeezing block 512 away from the sponge pad 511, and the other end of the pull rod 518 extends through and out of the outer frame 514. Mounting pushers 517 are symmetrically installed on both sides of the inner side of the outer frame 514, and ultraviolet light strips 515 are provided on the inner sides of both mounting pushers 517. One end of the ultraviolet light strip 515 away from the mounting pusher 517 is attached to both sides of the connecting cavity 516, and sponge pads 511 are connected to both sides of the lower end of the connecting cavity 516. The sponge pads 511 and the ultraviolet light strips 515 are arranged on the same straight line.

[0037] The reaction device 1 is fitted inside the placement slot 6. The cover 2, in conjunction with the placement slot 6, protects the reaction device 1. The adjustment frame 4, in conjunction with the movement of the processing device 5, injects the sample into the corresponding position inside the reaction device 1. The movable tube 54 on the processing device 5 is fixedly inserted into the adjustment frame 4. The disinfection component 51 is installed at the lower end of the movable tube 54 through the cooperation of the clamping rod 53 and the clamping ring 55. The linkage 52 extends through the disinfection component 51 and connects with the sampler 56, thereby driving the sampler 56 to move up and down in the connecting cavity 516 inside the disinfection component 51. The sponge pads 511 on the left and right sides of the connecting cavity 516 are attached to the sides of the sampler 56 under the action of the squeezing block 512 and the pulling rod 518. The ultraviolet lamp strip 515 is also connected to the sides of the sampler 56 under the action of the installation pusher 517, effectively disinfecting the sampler 56.

[0038] The reaction device 1 is installed inside the placement slot 6. The adjustment frame 4 moves left and right under the action of the slide rail 3 to adjust the position of the processing device 5, so that the processing device 5 can be vertically set on the reaction device 1 and the sample can be vertically injected into the reaction device 1.

[0039] The movable tube 54 on the processing device 5 is fixed on the adjustment frame 4, and the locking rod 53 will assist the movable tube 54 to be stably connected to the adjustment frame 4. The movable tube 54 is kept on the same straight line as the disinfection component 51 through the locking rod 53, so that the linkage 52 can stably drive the sampler 56 to move up and down inside the disinfection component 51 for disinfection.

[0040] The upper end of the outer frame 514 is fitted with a retaining ring 55 and a retaining rod 53, so that the linkage 52 vertically penetrates the outer frame 514 and extends into the connecting cavity 516 to connect with the sampler 56. The sampler 56 will then penetrate into the connecting cavity 516 and will be connected to the sponge pad 511 and the ultraviolet light strip 515 through the connecting cavity 516.

[0041] The working principle of the above technical solution is explained below: In use, the main body 8 is placed in the corresponding position, the material to be sampled is placed on the placement plate 7, and the reaction device 1 is fitted into the placement slot 6. The adjusting frame 4 moves left and right under the action of the slide rail 3 to adjust the position of the processing device 5. Through the movement of the adjusting frame 4 in conjunction with the processing device 5, the processing device 5 can be vertically erected on the reaction device 1. The processing device 5 is used to sample, so that the sample can be vertically injected into the reaction device 1. The reaction device 1 is fitted into the placement slot 6. The cover 2 and the placement slot 6 are hinged to protect the reaction device 1. The movable tube 54 on the processing device 5 is fixedly inserted into the adjusting frame 4, and the four external locking rods 53 are also... Subsequently, the auxiliary movable tube 54 is stably connected and installed on the adjusting frame 4. The lower end of the retaining ring 55 installed at the lower end of the retaining rod 53 will fit and connect to the top of the disinfection component 51, so that the movable tube 54 can be kept in the same straight line with the disinfection component 51 through the cooperation of the retaining rod 53 and the retaining ring 55. A linkage 52 is connected between the disinfection component 51 and the movable tube 54. The linkage 52 will extend into the two for adjustment. The lower end of the linkage 52 extends into the interior of the disinfection component 51 to connect with the sampler 56, so that the linkage 52 can stably drive the sampler 56 to move up and down inside the disinfection component 51 for disinfection. The linkage 52 will pass through the outer frame 514 on the disinfection component 51 and extend inward into the connecting cavity 51 in the middle position. In section 6, sponge pads 511 and ultraviolet light strips 515 are provided on both sides of the connecting cavity 516. The two sponge pads 511 are fitted onto two compression blocks 512. Pull rods 518 are inserted into the outer sides of each compression block 512. The two pull rods 518 extend through the outer frame 514, and their movement is controlled to adjust the position of the sponge pads 511 in coordination with the compression blocks 512. Limit fasteners 513 are connected to the pull rods 518, limiting their movement and ensuring the two sponge pads 511 are stably positioned on both sides of the lower end of the connecting cavity 516. Ultraviolet light strips 515 are provided on both sides of the connecting cavity 516, and the ultraviolet light strips 515... The pusher 517 is symmetrically installed, and the linkage 52 connects to the sampler 56, extending into the connecting cavity 516. The sponge pads 511 and ultraviolet lamp strips 515 on both sides of the sampler 56 will then adhere to both sides of the sampler 56. After sampling, the sampler 56 moves into the outer frame 514 under the pull of the linkage 52. The sponge pads 511 are moved inward by the pull rod 518 and the squeezing block 512 to fit tightly against the sampler 56. The position of the pull rod 518 is then fixed by the limiting fastener 513 to prevent the pull rod 518 from moving outward under force. After the sampler 56 moves into the connecting cavity 516, the sponge pads 511 will come into direct contact with it, absorbing and cleaning the residual sample liquid on the outer wall of the sampler 56.After the sampler 56 is processed, the sponge pad 511 is pulled outward by the pulling rod 518, which pulls the squeezing block 512 outward, causing the sponge pad 511 to move outward accordingly. Then, the position of the pulling rod 518 is limited by the limiting fastener 513, effectively fixing the sponge pad 511 in the corresponding position by the squeezing block 512. This prevents the sponge pad 511 from making secondary contact with the processed sampler 56 and causing re-contamination. The sampler 56 then moves upward to the position corresponding to the ultraviolet light strip 515. Two mounting pushers 517 push the ultraviolet light strip 515 outward, allowing the two ultraviolet light strips 515 to fit snugly against the outer wall of the sampler 56. This effectively disinfects the exterior of the sampler 56, reducing the risk of cross-contamination during secondary use and ensuring the accuracy of the test results.

[0042] Example 2 Please see Figures 4-7 , This invention provides a POCT microfluidic detection device. The reaction device 1 includes a turntable 11, a support platform 12, a tray 13, a sample detection platform 14, and reaction components 15. The turntable 11 is mounted on the support platform 12 and is connected to the bottom of the tray 13 through the support platform 12. The sample detection platform 14 is fixedly connected to the upper end of the tray 13, and multiple reaction components 15 are arranged in a ring at equal intervals on the sample detection platform 14. The reaction components 15 are fastened to the outer ring of the sample detection platform 14.

[0043] The support platform 12 is installed inside the placement slot 6. The turntable 11 drives the tray 13 to rotate inside the placement slot 6, so that the sample detection platform 14 will move accordingly, thereby adjusting the position of the reaction component 15 to be used in a state opposite to the processing device 5.

[0044] The reaction assembly 15 includes a reaction tube 151, a barrier assembly 152, a connecting tube 153, and a fixing plate 154. The upper end of the reaction tube 151 is fitted with the barrier assembly 152, and the lower end of the barrier assembly 152 is provided with the fixing plate 154. The fixing plate 154 is embedded in the upper end of the inner wall of the reaction tube 151, and the connecting tube 153 is provided in the middle position of the fixing plate 154. The upper end of the connecting tube 153 is connected to the barrier assembly 152.

[0045] The reaction tube 151 is externally fastened to the outer edge of the sample detection stage 14, so that the reaction tube 151 can be stably placed on the tray 13 for rotation via the sample detection stage 14.

[0046] The blocking component 152 includes a connecting plate 1521, a holding connector 1522, a slide rail 1523, and a swing plate 1524. The connecting plate 1521 has five slide rails 1523 connected to it, and the swing plates 1524 are respectively connected to the five slide rails 1523. The upper end of the swing plate 1524 is slidably connected to the slide rail 1523, and the five swing plates 1524 simultaneously open and close on the holding connector 1522 through the slide rails 1523. The holding connector 1522 is located in the middle of the connecting plate 1521.

[0047] The swing plate 1524 moves on the slide rail 1523 through the joint above it. When the five swing plates 1524 open at the same time, the insertion connector 1522 is exposed. Conversely, when the five swing plates 1524 close at the same time, the insertion connector 1522 effectively seals the area.

[0048] The insert connector 1522 is provided with an interface 5221, an airbag 5222, a snap-fit ​​connector 5223, a contact scraper 5224, and a connector 5225. The interface 5221 is located in the middle of the snap-fit ​​connector 5223, and the snap-fit ​​connector 5223 is provided with multiple connectors 5225 arranged in a ring at equal intervals. Each of the multiple connectors 5225 is provided with an airbag 5222, and the end of the connector 5225 away from the snap-fit ​​connector 5223 is connected to a contact scraper 5224. The multiple contact scrapers 5224 are connected by the connectors 5225 to form a ring structure on the outer ring of the interface 5221.

[0049] The interface 5221 is located in the middle of the connecting plate 1521. Multiple contact scrapers 5224 are connected to the connector 5225 and located on the outer ring of the interface 5221. Under the support of the airbag 5222, the connector 5225 can move and adjust the contact scrapers 5224 inside the interface 5221.

[0050] The working principle of the above technical solution is explained below: In use, the support platform 12 of the reaction device 1 is stably installed inside the placement slot 6. The turntable 11, under the action of the support platform 12, drives the tray 13 to rotate inside the placement slot 6. The sample detection stage 14 above it moves accordingly under the influence of the tray 13, thereby adjusting the position of the reaction component 15 to be opposite to the processing device 5 for use. The reaction tube 151 on the reaction component 15 is externally fastened to the outer edge of the sample detection stage 14, allowing the reaction tube 151 to be stably placed on the tray 13 for rotation via the sample detection stage 14. A fixing plate 154 is fitted to the upper end of the reaction tube 151, and the connecting pipe 153 located in the middle of the fixing plate 154 connects with the barrier component 15. When the two phases are connected, the outer wall of the connecting plate 1521 on the barrier component 152 will fit into the inner wall of the upper end of the reaction tube 151, so that the connecting plate 1521 is parallel to the upper end of the reaction tube 151. When the sample is injected into the reaction tube 151, the five swing plates 1524 installed on the connecting plate 1521 move on the slide rail 1523 through the connector above them. The five swing plates 1524 open simultaneously, so that the insert connector 1522 is exposed. Conversely, the five swing plates 1524 close simultaneously, and the insert connector 1522 effectively seals the tube. Then, the corresponding sample tube is installed on the sampler 56. The sampler 56 moves the sample tube down to the insert connector 1522. As the sampler 56 continues to move down, the sample tube moves down through the insert connector 1522. The interface 5221 on 522 penetrates the connecting tube 153 inside the fixed plate 154. The connecting tube 153 is connected to the interface 5221, allowing the sampler 56 to extend into the reaction tube 151 through the interface 5221 and the connecting tube 153. The sampler 56, in conjunction with the sample tube, injects the sample into the reaction tube 151. After the sample is injected, the sampler 56 moves the sample tube upward, and the outer wall of the sampler 56 fits tightly against the inner wall of the interface 5221. A contact scraper 5224 is connected to the outside of the interface 5221. Multiple contact scrapers 5224 are connected to the connector 5225 to form a ring structure on the outer ring of the interface 5221. The connector 5225, supported by the airbag 5222, can move accordingly. The contact scraper 5224 moves and adjusts within the interface 5221 to fit tightly against the sampler 56. During the movement of the sampler 56, the air bladder 5222 exhibits good elasticity, generating a certain rebound force after being subjected to force, pushing the connector 5225 outward. The connector 5225 then pulls the contact scraper 5224 outward, allowing it to fit snugly against the outer wall of the sampler 56. This effectively scrapes off any residual sample liquid from the outer wall of the sampler 56, preventing liquid adhering to the outer wall from accumulating at the bottom of the reaction tube and dripping onto the tray due to gravity during the sampler's movement, thus ensuring the cleanliness of the sample testing station.There will be no residual bacteria from different test liquids, ensuring the accuracy of the equipment's testing.

[0051] The foregoing has shown and described the basic principles, main features, and advantages of the present invention. It will be apparent to those skilled in the art that the invention is not limited to the details of the exemplary embodiments described above, and that the invention can be implemented in other specific forms without departing from its spirit or essential characteristics. Therefore, the embodiments should be considered illustrative and non-limiting in all respects, and the scope of the invention is defined by the appended claims rather than the foregoing description. Thus, all variations falling within the meaning and scope of equivalents of the claims are intended to be included within the scope of the invention. No reference numerals in the claims should be construed as limiting the scope of the claims.

[0052] Furthermore, it should be understood that although this specification describes embodiments, not every embodiment contains only one independent technical solution. This narrative style is merely for clarity. Those skilled in the art should consider the specification as a whole, and the technical solutions in each embodiment can also be appropriately combined to form other embodiments that can be understood by those skilled in the art.

Claims

1. A POCT microfluidic detection device, comprising a reaction device (1), a cover (2), a slide rail (3), an adjustment frame (4), a processing device (5), a placement slot (6), a placement plate (7), and a main body (8). The reaction device (1) is mounted on the placement slot (6), which is embedded inside the main body (8). The placement slot (6) is provided with the cover (2), which is connected to the placement slot (6) by a hinge. The upper end of the placement slot (6) faces the processing device (5), and the upper end of the processing device (5) is vertically inserted into the adjustment frame (4). The lower end of the adjustment frame (4) is provided on the slide rail (3), and the adjustment frame (4) is slidably connected to the slide rail (3). The slide rail (3) is fixed to the main body (8), and the main body (8) is provided with a placement plate (7) connected thereto. The processing device (5) is provided with a disinfection component (51), a linkage (52), a clamping rod (53), a movable tube (54), a retaining ring (55), and a sampler (56). The sampler (56) is connected through the inside of the disinfection component (51), and a retaining ring (55) is connected to the upper end of the disinfection component (51). Four clamping rods (53) are inserted into the retaining ring (55) in a circular arrangement at equal intervals, and the four clamping rods (53) are fixedly connected to the outer wall of the movable tube (54). The lower end of the movable tube (54) is provided with a linkage (52), and the upper end of the linkage (52) is movably connected to the inside of the movable tube (54). The end of the linkage (52) away from the movable tube (54) extends through into the inside of the disinfection component (51) and is connected to the sampler (56). The disinfection component (51) includes a sponge pad (511), a squeezing block (512), a limiting fastener (513), an outer frame (514), an ultraviolet lamp strip (515), a connecting cavity (516), a mounting pusher (517), and a pull rod (518). Two sponge pads (511) are provided, and the two sponge pads (511) are connected to the inner surfaces of the two squeezing blocks (512). A pull rod (518) is inserted into one end of the squeezing block (512) away from the sponge pad (511), and the pull rod (518)... 18) The other end extends through the outer frame (514). The two sides of the inner side of the outer frame (514) are symmetrically equipped with mounting pushers (517), and the inner sides of the two mounting pushers (517) are provided with ultraviolet light strips (515). The end of the ultraviolet light strip (515) away from the mounting pusher (517) is attached to both sides of the connecting cavity (516), and the lower sides of the connecting cavity (516) are connected with sponge pads (511). The sponge pads (511) and the ultraviolet light strips (515) are set on the same straight line. The reaction device (1) is fitted inside the placement slot (6). The cover (2) protects the reaction device (1) in conjunction with the placement slot (6). The sample is injected into the corresponding position inside the reaction device (1) by the movement of the adjustment frame (4) and the processing device (5). The movable tube (54) on the processing device (5) is fixedly inserted into the adjustment frame (4). The disinfection component (51) is installed at the lower end of the movable tube (54) by the cooperation of the clamp (53) and the clamp (55). The linkage (52) passes through... The sampler (56) is connected to the disinfection assembly (51), thereby causing the sampler (56) to move up and down in the connecting cavity (516) inside the disinfection assembly (51). The sponge pads (511) on the left and right sides of the connecting cavity (516) will adhere to the sides of the sampler (56) under the action of the squeezing block (512) and the pulling rod (518). The ultraviolet lamp strip (515) will also be connected to the sides of the sampler (56) under the action of the installation pusher (517), effectively disinfecting the sampler (56).

2. The POCT microfluidic detection device according to claim 1, characterized in that: The reaction device (1) is installed inside the placement slot (6). The adjustment frame (4) moves left and right under the action of the slide rail (3) to adjust the position of the processing device (5), so that the processing device (5) can be vertically set on the reaction device (1) and the sample can be vertically injected into the reaction device (1).

3. The POCT microfluidic detection device according to claim 1, characterized in that: The movable tube (54) on the processing device (5) is fixed on the adjustment frame (4), and the lever (53) will assist the movable tube (54) to be stably connected to the adjustment frame (4). The movable tube (54) is kept on the same straight line with the disinfection component (51) through the lever (53), so that the linkage (52) can stably drive the sampler (56) to move up and down inside the disinfection component (51) for disinfection.

4. The POCT microfluidic detection device according to claim 1, characterized in that: The upper end of the outer frame (514) is fitted with a retaining ring (55) and a retaining rod (53), so that the linkage (52) vertically penetrates the outer frame (514) and extends into the connecting cavity (516) to connect with the sampler (56). The sampler (56) will then penetrate into the connecting cavity (516) and will be connected to the sponge pad (511) and the ultraviolet lamp strip (515) through the connecting cavity (516).

5. A POCT microfluidic detection device according to claim 1, characterized in that: The reaction device (1) is provided with a turntable (11), a support platform (12), a tray (13), a sample detection platform (14), and reaction components (15). The turntable (11) is installed on the support platform (12) and the turntable (11) is connected to the bottom of the tray (13) through the support platform (12). The upper end of the tray (13) is fixedly connected to the sample detection platform (14), and the sample detection platform (14) is provided with a plurality of reaction components (15) arranged in a ring at equal intervals. The reaction components (15) are fastened to the outer ring of the sample detection platform (14). The support platform (12) is installed inside the placement slot (6). The turntable (11) drives the tray (13) to rotate inside the placement slot (6), so that the sample detection platform (14) will move accordingly, thereby allowing the position of the reaction component (15) to be adjusted to be opposite to the processing device (5) for use.

6. A POCT microfluidic detection device according to claim 5, characterized in that: The reaction assembly (15) is provided with a reaction tube (151), a barrier assembly (152), a connecting tube (153), and a fixing plate (154). The upper end of the reaction tube (151) is connected to the barrier assembly (152), and the lower end of the barrier assembly (152) is provided with a fixing plate (154). The fixing plate (154) is embedded in the upper end of the inner wall of the reaction tube (151), and the connecting tube (153) is provided in the middle position of the fixing plate (154) and connected to it. The upper end of the connecting tube (153) is connected to the barrier assembly (152). The reaction tube (151) is fastened to the outer edge of the sample detection stage (14), so that the reaction tube (151) can be stably placed on the tray (13) for rotation via the sample detection stage (14).

7. A POCT microfluidic detection device according to claim 6, characterized in that: The barrier assembly (152) is provided with a connecting plate (1521), a holding connector (1522), a slide rail (1523), and a swing plate (1524). The connecting plate (1521) is provided with five slide rails (1523) connected to it, and the five slide rails (1523) are respectively connected to the swing plates (1524). The upper end of the swing plate (1524) is slidably connected to the slide rail (1523), and the five swing plates (1524) simultaneously open and close on the holding connector (1522) through the slide rails (1523). The holding connector (1522) is located in the middle of the connecting plate (1521). The swing plate (1524) moves on the slide (1523) through the joint above it. When the five swing plates (1524) open at the same time, the insert connector (1522) is exposed. Conversely, when the five swing plates (1524) close at the same time, the insert connector (1522) effectively plays a sealing role.

8. A POCT microfluidic detection device according to claim 7, characterized in that: The insert connector (1522) is provided with an interface (5221), an air bladder (5222), a snap-fit ​​connector (5223), a contact scraper (5224), and a connector (5225). The interface (5221) is located in the middle of the snap-fit ​​connector (5223), and the snap-fit ​​connector (5223) is provided with multiple connectors (5225) arranged in a ring at equal intervals. Each of the multiple connectors (5225) is provided with an air bladder (5222), and the end of the connector (5225) away from the snap-fit ​​connector (5223) is connected to a contact scraper (5224). The multiple contact scrapers (5224) are connected by the connectors (5225) to form a ring structure on the outer ring of the interface (5221). The interface (5221) is located in the middle of the connecting plate (1521). Multiple contact scrapers (5224) and connectors (5225) are connected and located on the outer ring of the interface (5221). Under the support of the airbag (5222), the connectors (5225) can move and adjust the contact scrapers (5224) inside the interface (5221).

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