Temperature control and speed control type multi-groove section dyeing device

By designing a temperature- and speed-controlled multi-groove section staining device, the problem of uneven contact between the staining solution and the section sample is solved by using thermal expansion gas to drive shaking and electromagnets to adjust the shaking amplitude, thus achieving staining uniformity and diagnostic accuracy.

CN121783657APending Publication Date: 2026-04-03HENAN ACADEMY OF MEDICAL SCIENCES
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
Filing Date
2025-12-31
Publication Date
2026-04-03

AI Technical Summary

Technical Problem

In existing staining devices, the contact between the staining solution and the slide sample is uneven, resulting in uneven staining and affecting the accuracy of pathological diagnosis and scientific research data.

Method used

The device employs a temperature- and speed-controlled multi-slide staining apparatus. A heating plate causes thermal expansion gas to propel the moving component within the moving tank, which in turn causes the placement component to shake, promoting uniform contact between the staining solution and the slide sample. The shaking amplitude is adjusted by an electromagnet to accommodate different slide and staining solution characteristics.

Benefits of technology

This method achieves full and uniform contact between the staining solution and the slide sample, avoiding uneven staining and improving the accuracy of pathological diagnosis and research data.

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Abstract

The invention provides a temperature control and speed control type multi-groove section dyeing device and belongs to the technical field of section dyeing, the temperature control and speed control type multi-groove section dyeing device comprises an equipment body, a containing groove is formed in the equipment body, a plurality of installation assemblies are arranged in the containing groove, a plurality of installation grooves distributed at equal intervals are formed in each installation assembly, and the installation grooves are communicated with the containing groove. Mounting grooves are formed in the mounting assemblies, placing pieces are arranged in the mounting grooves, limiting sliding grooves are further formed in the mounting assemblies, sliding pieces are slidably connected in the limiting sliding grooves, transfer grooves communicating with the corresponding limiting sliding grooves are formed in the bottoms of the mounting grooves, and adjusting clamping pieces are arranged at the bottoms of the placing pieces; each sliding piece is provided with clamping grooves which are the same as the corresponding adjusting clamping pieces in number and correspond to the corresponding adjusting clamping pieces in position, when the sliding pieces move in the limiting sliding grooves, the corresponding placing pieces can be selectively driven to shake through cooperation of the adjusting clamping pieces and the clamping grooves, and the dyeing uniformity can be improved.
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Description

Technical Field

[0001] This invention belongs to the field of section staining technology, specifically relating to a temperature- and speed-controlled multi-groove section staining device. Background Technology

[0002] Section staining is a crucial technique that involves preparing thin sections of biological tissue and then staining them with specific dyes to clearly reveal their microscopic structure under a microscope. By displaying contrasting colors in different cellular components, it significantly enhances the contrast of observation, allowing doctors and researchers to identify cell morphology, analyze tissue structure, and detect abnormal changes. Therefore, it has become an indispensable cornerstone method in pathological diagnosis and life science research. In biological experiments and pathological examinations, section staining is a key step, and its staining effect directly impacts subsequent observation and analysis results.

[0003] Chinese patent application CN202410032488.X discloses a pathology specimen slide staining device, specifically relating to the field of slide staining. The device includes a chassis and a slide holder. The slide holder holds multiple slides with specimen slides. The chassis contains several staining tanks and a robotic arm that transports the slide holder into the staining tanks for staining the specimen slides. At least one holding component is mounted on the slide holder, including a support frame for holding the slides. A fixing frame is located below the support frame. This invention not only prevents tissue fragments from absorbing water, swelling, and rupturing, thus avoiding contamination of the staining solution in the staining tank, but also controls the flow of the staining solution into the inner cavity to stain the specimen slides. Combined with the dual staining effect of external staining solution permeating the filter paper and contacting the specimen slides, the device allows for faster and more thorough contact between the specimen slides and the solution, improving staining and soaking efficiency and shortening staining time.

[0004] However, existing staining devices often fail to achieve effective and uniform contact between the staining solution and the slide during the staining process. This is primarily due to the relatively static or simple mechanical movement of the contact between the staining solution and the slide sample. Specifically, in traditional static immersion or simple overall lifting / translation processes, the staining solution relies mainly on its own molecular Brownian motion for slow diffusion. This passive mass transfer method easily forms a stable "concentration boundary layer" on the microscopic surface of the slide sample. Especially for pathological slides with complex tissue structures, the staining solution struggles to effectively penetrate into the interstitial spaces and deep cellular crypts. This also leads to the retention of metabolic products or old staining solutions, resulting in uneven staining where some areas (such as edges or surfaces) are excessively dark, while other areas (such as the core or interior of complex structures) are lightly stained or even unstained. This not only blurs the contrast between cell nucleus and cytoplasm and makes it difficult to distinguish microscopic structures, but it can also directly lead to deviations in pathological diagnosis or distortion of research data due to color misjudgment. Furthermore, existing devices lack a precise shaking control mechanism and cannot actively break the concentration boundary layer, causing metabolic products or old staining solutions to remain, further exacerbating the uneven staining.

[0005] Therefore, in order to solve the above problems, it is necessary to provide a temperature- and speed-controlled multi-groove section staining device. Summary of the Invention

[0006] The purpose of this invention is to provide a temperature- and speed-controlled multi-tank section staining device, which aims to solve the problem in the prior art that the staining solution cannot effectively and evenly contact the section.

[0007] To achieve the above objectives, the present invention provides the following technical solution: A temperature- and speed-controlled multi-groove section staining device includes a main body with a receiving groove on the main body, and multiple sets of mounting components are provided in the receiving groove. Each set of mounting components has multiple equally spaced mounting slots, each mounting slot contains a placement component, and each mounting component also has a limiting groove, in which a sliding component is slidably connected. The bottom of each mounting slot has a transition groove that communicates with the corresponding limiting groove, and the bottom of each placement component has an adjusting clip. Each sliding component has a number of corresponding adjusting clips and corresponding slots. When the sliding component moves in the limiting groove, the adjustment clips and slots work together to selectively cause the corresponding placement component to shake.

[0008] Preferably, the adjusting clip includes an adjusting member fixedly connected to the bottom of the corresponding placement member, the outer wall of the adjusting member being slidably connected to the inner wall of the transition groove, a sealed chamber being formed inside the placement member, each of the sealed chambers being filled with thermally expanding gas, a moving groove being formed inside the adjusting member communicating with the sealed chamber, a moving member being slidably connected inside the moving groove, an elastic member being connected between the top of the moving member and the inner wall of the sealed chamber, and a snap-fit ​​member being fixedly connected to the bottom of the moving member.

[0009] Preferably, each of the adjusting members has two symmetrically arranged extrusion grooves on its outer wall, each extrusion groove has a friction member slidably connected inside, each extrusion groove has a guide groove communicating with the corresponding moving groove, each guide groove has a wedge member slidably connected to the corresponding friction member, each moving member has a number of wedge grooves corresponding to the guide grooves and in the same position, and each wedge member is slidably connected to the corresponding wedge groove.

[0010] Preferably, each of the mounting slots has two symmetrically arranged connecting slots inside, each connecting slot has a connecting rod rotatably connected to the corresponding placement component, each placement component has a placement slot, each placement slot has a dyeing cup installed inside, and each placement slot has a heating plate at the bottom.

[0011] Preferably, an installation chamber communicating with the limiting slide groove is provided on the outer side of the device body located on the end face of the sliding member. Each installation chamber is fixedly connected with a rotating shaft that is the same number as the sliding member and corresponds to the position of the sliding member. Each rotating shaft is rotatably connected with a connecting member that is fixedly connected to the corresponding sliding member.

[0012] Preferably, a drive chamber communicating with the installation chamber is provided on one side of the main body of the device. A drive motor is provided inside the drive chamber. An eccentric component is fixedly connected to the output shaft of the drive motor. An adjustment groove is provided inside the eccentric component. An isolation plate is fixedly connected inside the adjustment groove. The isolation plate can divide the adjustment groove into a first chamber and a second chamber. An adjustment screw is rotatably connected inside the isolation plate. One end of the adjustment screw is rotatably connected to the inner wall of the second chamber. The other end of the adjustment screw is located inside the first chamber and is fixedly connected to a first gear. A movable component that is slidably connected to the inner wall of the second chamber is rotatably connected to the outer wall of the adjustment screw.

[0013] Preferably, each of the mounting chambers is equipped with a sealing plate, wherein the sealing plate located on one side of the drive motor is provided with an adjusting motor concentric with the output shaft of the drive motor. The output shaft of the adjusting motor passes through the sealing plate and is fixedly connected to a transition shaft. The outer wall of the other end of the transition shaft is fixedly connected to a fixing member. A third chamber is opened inside the fixing member. An electromagnet is fixedly connected inside the third chamber. A magnet is slidably connected inside the third chamber. The magnetic poles of the magnet and the electromagnet on the opposite side are arranged in the same manner. The end of the magnet away from the electromagnet is fixedly connected to an adjusting shaft that passes through the fixing member. The other end of the adjusting shaft is located inside the first chamber and is fixedly connected to a second gear.

[0014] Preferably, the second gear can mesh with the first gear. When the electromagnet is energized, the magnetic force generated by the electromagnet can cause the magnet to move away from the electromagnet, allowing the second gear to enter the first chamber and mesh with the first gear. At this time, the driving adjustment motor can be used to adjust the position of the moving part.

[0015] Preferably, a drive rod rotatably connected to the movable component is rotatably connected to the connecting component, and a synchronizing rod is connected between the connecting components on one side. When the drive motor rotates, it can drive multiple connecting components to move synchronously through the drive rod and the synchronizing rod.

[0016] Preferably, the main body of the device is also equipped with an oxygen supply device and a control panel.

[0017] Compared with the prior art, the beneficial effects of the present invention are: This invention activates a heating plate at the bottom of a specific staining cup, transferring heat to the sealed chamber of the placement component. This causes the thermally expanding gas inside to expand, generating pressure that pushes a moving component downwards within a moving groove. This, in turn, drives a snap-fit ​​component to extend downwards and insert into a snap-fit ​​slot, achieving automatic snap-fit. At this point, a drive motor starts, using a drive rod and a synchronizing rod to move all sliding components back and forth within an arc-shaped limiting groove. This causes the corresponding placement component to shake rhythmically. This shaking forces the staining solution within the staining cup to turbulently flow, effectively breaking the "concentration boundary layer" and promoting full and uniform contact and exchange between the staining solution and the microscopic surface and complex internal structure of the slide sample. This avoids uneven contact that occurs in relatively static or simple mechanical contact modes.

[0018] This invention, by controlling the on / off state of the electromagnet, can adjust the meshing state of the second gear and the first gear. When the second gear and the first gear are meshing, the position of the movable part on the adjusting screw can be precisely adjusted by controlling the rotation direction of the adjusting motor. When the movable part is close to the output shaft of the drive motor, the shaking amplitude decreases, which is suitable for fine structures or low-viscosity dye solutions. When the movable part is far away from the output shaft of the drive motor, the shaking amplitude increases, which is suitable for thick tissues or high-viscosity dye solutions. This allows for adjustment of the shaking amplitude, ensuring that sections in different staining tanks can obtain the best dye exchange effect, avoiding staining defects caused by excessive or insufficient shaking. Furthermore, when combined with the selective mechanism of the staining cup, it enables customized uniform staining of sections in multiple tanks. Attached Figure Description

[0019] The accompanying drawings are provided to further illustrate the invention and form part of the specification. They are used in conjunction with embodiments of the invention to explain the invention and do not constitute a limitation thereof. In the drawings: Figure 1 This is a schematic diagram of the overall structure of the present invention; Figure 2 This is a schematic diagram of the structure of the mounting component of the present invention; Figure 3 This is a schematic diagram of the limiting slide groove of the present invention; Figure 4 This is a schematic diagram of the structure of the placement component of the present invention; Figure 5 This is a schematic diagram of the internal structure of the placement component of the present invention; Figure 6 This is a schematic diagram of the structure of the moving part of the present invention; Figure 7 This is a schematic diagram of the structure of the drive chamber of the present invention; Figure 8 This is a schematic diagram of the structure of the connector and the sliding member of the present invention; Figure 9 This is a schematic diagram of the eccentric component of the present invention; Figure 10 This is a schematic diagram of the internal structure of the fixing ring of the present invention.

[0020] In the diagram: 1. Main body of the equipment; 11. Receiving groove; 12. Installation chamber; 13. Rotating shaft; 14. Connecting piece; 15. Synchronizing rod; 2. Installation assembly; 21. Installation groove; 22. Limiting slide groove; 23. Sliding piece; 24. Adapter groove; 25. Slot; 26. Connecting groove; 27. Connecting rod; 3. Placement piece; 31. Placement groove; 32. Dyeing cup; 33. Heating plate; 4. Adjusting clip; 41. Adjusting piece; 42. Sealed chamber; 43. Moving groove; 44. Moving piece; 45. Elastic piece; 46. Clip; 47. Extrusion groove; 48. Friction 49. Wiping component; 410. Guide groove; 411. Wedge-shaped component; 5. Wedge-shaped groove; 5. Drive chamber; 51. Drive motor; 52. Eccentric component; 53. Adjusting groove; 54. Isolation plate; 55. First chamber; 56. Second chamber; 57. Adjusting screw; 58. First gear; 59. Moving component; 510. Sealing plate; 511. Drive rod; 6. Adjusting motor; 61. Adapter shaft; 62. Fixing component; 63. Third chamber; 64. Electromagnet; 65. Magnetic component; 66. Adjusting shaft; 67. Second gear; 7. Oxygen supply equipment; 8. Control panel. Detailed Implementation

[0021] The technical solutions of the embodiments of the present invention will be clearly and completely described below with reference to the accompanying drawings. Obviously, the described embodiments are only some embodiments of the present invention, and not all embodiments. Based on the embodiments of the present invention, all other embodiments obtained by those skilled in the art without creative effort are within the scope of protection of the present invention. Example 1

[0022] In existing staining devices, the staining solution cannot effectively and evenly contact the slides during the staining process. This is mainly because the contact mode between the staining solution and the slide sample is always relatively static or simple mechanical movement. Specifically, in traditional static immersion or simple overall lifting / translation processes, the staining solution mainly relies on its own molecular Brownian motion for slow diffusion. This passive mass transfer mode is very likely to form a stable "concentration boundary layer" on the microscopic surface of the slide sample. Especially for pathological slides with complex tissue structures, the staining solution has difficulty effectively penetrating into the interstitial spaces and deep cellular crypts. At the same time, it also leads to the retention of metabolic products or old staining solution, which is difficult to remove. This ultimately results in a phenomenon of "uneven staining" in which some areas of the slide are stained too darkly (such as the edges or surface), while other areas (such as the core or the interior of complex structures) are stained lightly or even unstained. This not only blurs the contrast between cell nucleus and cytoplasm and makes it difficult to distinguish microscopic structures, but may also directly lead to deviations in pathological diagnosis or distortion of scientific research data due to color misinterpretation.

[0023] Please see Figures 1 to 6A temperature- and speed-controlled multi-groove section staining device includes a main body 1, a receiving groove 11 on the main body 1, and multiple sets of installation components 2 inside the receiving groove 11. Each set of mounting components 2 has multiple equally spaced mounting slots 21, and each mounting slot 21 is provided with a placement component 3. Each mounting component 2 also has a limiting slide groove 22, in which a sliding component 23 is slidably connected. The bottom of each mounting slot 21 has a transition groove 24 that communicates with the corresponding limiting slide groove 22. The bottom of each placement component 3 is provided with an adjusting clip 4. Each sliding component 23 has a number of corresponding adjusting clips 4 and corresponding slots 25. When the sliding component 23 moves in the limiting slide groove 22, the corresponding placement component 3 can be selectively driven to shake by the cooperation of the adjusting clip 4 and the slot 25.

[0024] The adjusting clip 4 includes an adjusting member 41 fixedly connected to the bottom of the corresponding placement member 3. The outer wall of the adjusting member 41 is slidably connected to the inner wall of the transition groove 24. The placement member 3 has a sealed chamber 42 inside, and each sealed chamber 42 is filled with thermal expansion gas. The adjusting member 41 has a moving groove 43 connected to the sealed chamber 42 inside. The moving groove 43 is slidably connected to a moving member 44 inside. The top of the moving member 44 is connected to the inner wall of the sealed chamber 42 by an elastic member 45. The bottom of the moving member 44 is fixedly connected to a snap-fit ​​member 46. When the snap-fit ​​member 46 is located inside the corresponding slot 25, the sliding member 23 can drive the corresponding placement member 3 to move synchronously.

[0025] In the initial state, i.e. when the equipment is not running, the moving part 44 is located inside the moving groove 43. At this time, the snap-fit ​​part 46 cannot be inserted into the slot 25 and is in a disengaged state. When the heating plate 33 heats the dyeing cup 32, it can also raise the temperature of the thermal expansion gas inside its sealed chamber 42, causing the thermal expansion gas to expand and push the moving part 44 downward inside the moving groove 43, allowing the snap-fit ​​part 46 to be inserted into the slot 25.

[0026] Each adjusting member 41 has two symmetrically arranged extrusion grooves 47 on its outer wall. Each extrusion groove 47 has a friction member 48 slidably connected inside it. Each extrusion groove 47 has a guide groove 49 that communicates with the corresponding moving groove 43 inside it. Each guide groove 49 has a wedge-shaped member 410 that is slidably connected to the corresponding friction member 48 inside it. Each moving member 44 has a number of wedge-shaped grooves 411 that are the same as the corresponding guide grooves 49 and are in the same position. Each wedge-shaped member 410 is slidably connected to the corresponding wedge-shaped groove 411.

[0027] When the moving part 44 moves upward relative to the adjusting part 41, the wedge 410 moves along the inclined surface of the wedge groove 411, driving the friction part 48 to move radially outward and press against the inner wall of the transition groove 24. When the moving part 44 moves downward, the friction part 48 retracts radially inward into the extrusion groove 47.

[0028] When the moving part 44 moves upward inside the moving groove 43, the wedge part 410 moves inside the wedge groove 411, which allows the friction part 48 to move away from the adjusting part 41. The friction part 48 can press against the transition groove 24, which can limit the placement part 3 and facilitate the installation of the dyeing cup 32. When the moving part 44 moves downward inside the moving groove 43, the wedge part 410 moves inside the wedge groove 411, which allows the friction part 48 to move closer to the adjusting part 41. The friction part 48 can enter the corresponding pressing groove 47, and the friction part 48 no longer presses against the transition groove 24, which allows the placement part 3 to be in a "moving state".

[0029] Each mounting slot 21 has two symmetrically arranged connecting slots 26 inside. Each connecting slot 26 has a connecting rod 27 that is rotatably connected to the corresponding placement piece 3. Each placement piece 3 has a placement slot 31. Each placement slot 31 has a dyeing cup 32 installed inside. Each placement slot 31 has a heating plate 33 at its bottom.

[0030] The main body of the equipment 1 is also equipped with oxygen supply equipment 7 and control panel 8.

[0031] The oxygen supply device 7 is used to provide oxygen during the dyeing process. The oxygen supply device 7 is existing technology and will not be described in detail here.

[0032] The dyeing cup 32 can be heated by the heating plate 33, and the heating temperature of the heating plate 33 can be controlled by the control panel 8. This is existing technology and will not be described in detail.

[0033] The outer side of the main body 1 of the device located on the end face of the sliding member 23 is provided with an installation chamber 12 that communicates with the limiting slide groove 22. Each installation chamber 12 is fixedly connected with a rotating shaft 13 that is the same number as the sliding member 23 and has a corresponding position. Each rotating shaft 13 is rotatably connected with a connecting member 14 that is fixedly connected to the corresponding sliding member 23.

[0034] The limiting groove 22 and the sliding member 23 are both arc-shaped. Each rotating shaft 13 and connecting rod 27 are located at the center of the corresponding limiting groove 22. When the locking member 46 is located inside the corresponding slot 25, it ensures that the sliding member 23 can drive the corresponding placement member 3 to shake. The two sides of the sliding member 23 are wedge-shaped, which is to facilitate the subsequent entry of the locking member 46 into the slot 25. When the moving member 44 moves downward inside the moving groove 43, since the sealed chamber 42 is filled with gas, when the locking member 46 contacts and squeezes the wedge-shaped surface of the sliding member 23, the moving member 44 can retract upward to a certain extent. Then, when the locking member 46 corresponds to the position of the slot 25, the moving member 44 can move downward again, so that the locking member 46 enters the slot 25 for locking.

[0035] It should be noted that during use, when the drive motor 51 rotates, it can drive multiple connecting parts 14 to move synchronously through the drive rod 511 and the synchronous rod 15, and can drive multiple sliding parts 23 to reciprocate within the limiting slide groove 22. At this time, by activating the corresponding heating plate 33 to heat the dyeing cup 32, the thermal expansion gas inside the corresponding sealed chamber 42 can be heated, causing the thermal expansion gas to expand and push the moving part 44 to move downward within the moving groove 43, allowing the snap-fit ​​part 46 to insert into the corresponding snap-fit ​​groove 25. Simultaneously, when the moving part 44 moves downward within the moving groove 43, the wedge-shaped part 410 moves within the wedge-shaped groove 411, causing the friction part 48 to move towards the adjusting part 41, and the friction part 48 can enter the corresponding... Inside the squeezing groove 47, the friction element 48 no longer squeezes and contacts the transfer groove 24, allowing the placement element 3 to be in a "moving state". At this time, the sliding element 23 moves inside the limiting groove 22, which can drive the corresponding placement element 3 to shake regularly around the connecting rod 27, and can make the corresponding staining cup 32 shake synchronously. This shaking forces the staining solution in the staining cup 32 to generate turbulence, effectively breaking the "concentration boundary layer" and promoting full and uniform contact and exchange between the staining solution and the microscopic surface and complex structure of the slide sample. This achieves selective shaking of the staining cup 32, and the shaking can make the staining solution inside the staining cup 32 contact the slide sample more evenly, avoiding the phenomenon of uneven contact in the contact mode of relatively static or simple mechanical movement.

[0036] After heating stops, the gas in the sealed chamber 42 cools and contracts, and the elastic element 45 rebounds elastically, which can reset the moving element 44 and move it upward. The locking element 46 then exits from the slot 25, releasing the linkage. At the same time, the friction element 48 extends outward again, relocking the placement element 3 and restoring it to a stable state.

[0037] In summary, this invention activates the heating plate 33 at the bottom of a specific staining cup 32, transferring heat to the sealed chamber 42 of the placement component 3. This causes the thermally expanding gas inside to expand due to the heat, generating pressure that pushes the moving component 44 downward within the moving groove 43. This, in turn, drives the snap-fit ​​component 46 downward, allowing it to insert into the snap-fit ​​slot 25 for automatic snap-fit. At this time, the drive motor 51 starts, driving all the sliding components 23 to reciprocate within the arc-shaped limiting groove 22 via the drive rod 511 and the synchronizing rod 15. This causes the corresponding placement component 3 to shake regularly. This shaking forces the staining solution within the staining cup 32 to turbulently flow, effectively breaking the "concentration boundary layer" and promoting full and uniform contact and exchange between the staining solution and the microscopic surface and complex internal structure of the slide sample. This avoids uneven contact that occurs in relatively static or simple mechanical contact modes. Example 2

[0038] Based on the above embodiments, although the selective shaking mechanism effectively improves the contact uniformity between the staining solution and the slide, the amplitude and frequency of this shaking mode are relatively fixed and cannot be dynamically adjusted according to the specific needs of the slide sample (such as tissue thickness, structural complexity, or staining solution viscosity). Specifically, a fixed amplitude of shaking may not be able to fully adapt to the mass transfer requirements of different staining stages. For slides with dense structures or large thickness, a larger amplitude of shaking is required to enhance the penetration of the staining solution. For fragile or fine structures, excessive shaking may cause slide damage or staining solution splashing. In addition, in the process of parallel staining in multiple tanks, different staining cups may require different shaking parameters, but the uniform driving mechanism of Embodiment 1 lacks flexibility and is prone to over- or under-staining of some slides, affecting staining consistency and efficiency.

[0039] Please see Figures 7 to 10 A drive chamber 5, which communicates with the installation chamber 12, is provided on one side of the main body 1. A drive motor 51 is provided inside the drive chamber 5. An eccentric component 52 is fixedly connected to the output shaft of the drive motor 51. An adjustment groove 53 is provided inside the eccentric component 52. An isolation plate 54 is fixedly connected inside the adjustment groove 53. The isolation plate 54 can divide the adjustment groove 53 into a first chamber 55 and a second chamber 56. An adjustment screw 57 is rotatably connected inside the isolation plate 54. One end of the adjustment screw 57 is rotatably connected to the inner wall of the second chamber 56. The other end of the adjustment screw 57 is located inside the first chamber 55 and is fixedly connected to a first gear 58. A movable component 59, which is slidably connected to the inner wall of the second chamber 56, is rotatably connected to the outer wall of the adjustment screw 57.

[0040] Each installation chamber 12 is equipped with a sealing plate 510. The sealing plate 510 located on one side of the drive motor 51 is equipped with an adjusting motor 6 concentric with the output shaft of the drive motor 51. The output shaft of the adjusting motor 6 passes through the sealing plate 510 and is fixedly connected to a transition shaft 61. The outer wall of the other end of the transition shaft 61 is fixedly connected to a fixing member 62. A third chamber 63 is opened inside the fixing member 62. An electromagnet 64 is fixedly connected inside the third chamber 63. A magnet 65 is slidably connected inside the third chamber 63. The magnetic poles of the magnet 65 and the electromagnet 64 are arranged in the same direction on the opposite side. The end of the magnet 65 away from the electromagnet 64 is fixedly connected to an adjusting shaft 66 that passes through the fixing member 62. The other end of the adjusting shaft 66 is located inside the first chamber 55 and is fixedly connected to a second gear 67.

[0041] Both the regulating motor 6 and the electromagnet 64 are electrically connected to the control panel 8 and can be controlled and adjusted through the control panel 8. This is existing technology and will not be described in detail here.

[0042] The magnetic poles of the magnet 65 and the electromagnet 64 on opposite sides are arranged in the same way. If the end of the magnet 65 near the electromagnet 64 is the N pole, then the end of the electromagnet 64 near the magnet 65 is also the N pole, and vice versa. If the end of the magnet 65 near the electromagnet 64 is the S pole, then the end of the electromagnet 64 near the magnet 65 is also the S pole.

[0043] The second gear 67 can mesh with the first gear 58 in the vertical direction. The first gear 58 is coaxially arranged with the output shaft of the drive motor 51. When the electromagnet 64 is not energized, the magnet 65 can move towards the electromagnet 64 through magnetic force to make contact, since there is an iron core inside the electromagnet 64. At this time, the second gear 67 can come out from the first chamber 55 and disengage from the first gear 58. When the electromagnet 64 is energized, like poles repel each other, and the magnetic force generated by the electromagnet 64 can make the magnet 65 move away from the electromagnet 64. At this time, the second gear 67 can enter the first chamber 55 and mesh with the first gear 58. At this time, the drive adjustment motor 6 can realize the position adjustment of the moving part 59.

[0044] When it is necessary to adjust the shaking amplitude, first control the electromagnet 64 to be energized. Like poles repel each other, and the magnetic force generated by the electromagnet 64 can make the magnet 65 move away from the electromagnet 64, pushing the adjusting shaft 66 and the second gear 67 to move into the first chamber 55 until the second gear 67 and the first gear 58 enter a perpendicular meshing state. Subsequently, the drive adjustment motor 6 drives the adapter shaft 61 to rotate, and through the fixing part 62 drives the adjustment shaft 66 to rotate the second gear 67. The second gear 67 drives the first gear 58, which meshes with it, to rotate. The first gear 58 then drives the adjustment screw 57 to rotate synchronously, enabling the movable part 59 to move linearly along the screw shaft. By controlling the direction of rotation, the movable part 59 can be precisely positioned at different positions on the adjustment screw 57. After adjustment, the drive adjustment motor 6 is stopped. Since there is an iron core inside the electromagnet 64, the magnet 65 can move towards the electromagnet 64 through magnetic force. The second gear 67 disengages from the first gear 58, thereby locking the new position of the movable part 59 and preventing accidental displacement during the drive process.

[0045] The movable part 59 is rotatably connected to the drive rod 511 which is rotatably connected to the connector 14. A synchronizing rod 15 is connected between the connectors 14 on one side. When the drive motor 51 rotates, it can drive multiple connectors 14 to move synchronously through the drive rod 511 and the synchronizing rod 15, thereby driving the sliding part 23 to reciprocate within the limiting groove 22.

[0046] When the movable part 59 is adjusted to be close to the center of the output shaft of the drive motor 51, that is, close to the end of the isolation plate 54, the distance between it and the rotation center is small and the effective eccentricity is short. Under the drive of this small eccentricity, the angular amplitude of the sliding part 23 driven by the drive rod 511 to swing back and forth also decreases, which ultimately manifests as the dyeing cup 32 making a low-amplitude, gentle sway.

[0047] When the movable part 59 is adjusted to be far away from the center of the output shaft of the drive motor 51, that is, far away from the isolation plate 54, the distance between it and the rotation center increases, the effective eccentricity becomes longer, and the angular amplitude of the sliding part 23 driven by the drive rod 511 to swing back and forth under this large eccentricity also increases, which ultimately manifests as the dyeing cup 32 shaking with high amplitude and violently.

[0048] It should be noted that during the staining process, the user can adjust the meshing state of the second gear 67 and the first gear 58 by controlling the on and off of the electromagnet 64 according to the characteristics of the slide sample and the properties of the staining solution. When the second gear 67 and the first gear 58 are meshing, the position of the movable part 59 on the adjusting screw 57 can be precisely adjusted by controlling the rotation direction of the adjusting motor 6. The change in position of the movable part 59 alters the lever ratio and movement trajectory of the drive rod 511, thereby adjusting the swaying amplitude of the sliding part 23. When the movable part 59 approaches the output shaft of the drive motor 51, the swaying amplitude decreases, suitable for fine structures or low-viscosity staining solutions. When the movable part 59 moves away from the output shaft of the drive motor 51, the swaying amplitude increases, suitable for thick tissues or high-viscosity staining solutions. This adjustment mechanism can regulate the swaying amplitude, ensuring that sections in different staining tanks can obtain the best staining solution exchange effect, while avoiding staining defects caused by excessive or insufficient swaying. After the drive motor 51 is started, the rotational motion is converted into the reciprocating swaying of the sliding part 23 through the eccentric part 52 and the drive rod 511, combined with the selective mechanism of the staining cup 32, to achieve customizable uniform staining of sections in multiple tanks.

[0049] In summary, by controlling the on / off state of the electromagnet 64, this invention can adjust the meshing state of the second gear 67 and the first gear 58. When the second gear 67 and the first gear 58 are meshed, the position of the movable part 59 on the adjusting screw 57 can be precisely adjusted by controlling the rotation direction of the adjusting motor 6. When the movable part 59 is close to the output shaft of the drive motor 51, the shaking amplitude is reduced, which is suitable for fine structures or low-viscosity dye solutions. When the movable part 59 is far away from the output shaft of the drive motor 51, the shaking amplitude is increased, which is suitable for thick tissues or high-viscosity dye solutions. This allows for adjustment of the shaking amplitude, ensuring that sections in different staining tanks can obtain the best dye exchange effect, avoiding staining defects caused by excessive or insufficient shaking. Furthermore, combined with the selective mechanism of the staining cup 32, it enables customized uniform staining of sections in multiple tanks.

[0050] Finally, it should be noted that the above descriptions are merely preferred embodiments of the present invention and are not intended to limit the present invention. Although the present invention has been described in detail with reference to the foregoing embodiments, those skilled in the art can still modify the technical solutions described in the foregoing embodiments or make equivalent substitutions for some of the technical features. Any modifications, equivalent substitutions, improvements, etc., made within the spirit and principles of the present invention should be included within the protection scope of the present invention.

Claims

1. A temperature- and speed-controlled multi-groove section staining device, comprising a main body, characterized in that: The main body of the equipment is provided with a receiving groove, and multiple sets of installation components are provided in the receiving groove; Each set of mounting components has multiple equally spaced mounting slots, each mounting slot contains a placement component, and each mounting component also has a limiting groove, in which a sliding component is slidably connected. The bottom of each mounting slot has a transition groove that communicates with the corresponding limiting groove, and the bottom of each placement component has an adjusting clip. Each sliding component has a number of corresponding adjusting clips and corresponding slots. When the sliding component moves in the limiting groove, the adjustment clips and slots work together to selectively cause the corresponding placement component to shake.

2. The temperature- and speed-controlled multi-groove section staining apparatus according to claim 1, characterized in that: The adjusting clip includes an adjusting member fixedly connected to the bottom of the corresponding placement piece. The outer wall of the adjusting member is slidably connected to the inner wall of the transition groove. A sealed chamber is opened inside the placement piece. Each sealed chamber is filled with thermally expanding gas. A movable groove is opened inside the adjusting member and communicates with the sealed chamber. A movable member is slidably connected inside the movable groove. An elastic member is connected between the top of the movable member and the inner wall of the sealed chamber. A snap-fit ​​member is fixedly connected to the bottom of the movable member.

3. The temperature- and speed-controlled multi-groove section staining apparatus according to claim 2, characterized in that: Each of the adjusting components has two symmetrically arranged extrusion grooves on its outer wall. Each extrusion groove has a friction component slidably connected inside it. Each extrusion groove has a guide groove that communicates with the corresponding moving groove inside it. Each guide groove has a wedge-shaped component that is slidably connected to the corresponding friction component inside it. Each moving component has wedge-shaped grooves that are the same number and position as the corresponding guide grooves. Each wedge-shaped component is slidably connected to the corresponding wedge-shaped groove.

4. The temperature- and speed-controlled multi-groove section staining apparatus according to claim 1, characterized in that: Each of the mounting slots has two symmetrically arranged connecting slots inside, and each connecting slot has a connecting rod that is rotatably connected to the corresponding placement component. Each placement component has a placement slot, and each placement slot has a dyeing cup installed inside. Each placement slot has a heating plate at its bottom.

5. The temperature- and speed-controlled multi-groove section staining apparatus according to claim 1, characterized in that: The outer side of the main body of the device located on the end face of the sliding member is provided with an installation chamber that communicates with the limiting slide groove. Each installation chamber is fixedly connected with a rotating shaft that is the same number as the sliding member and corresponds to the position of the sliding member. Each rotating shaft is rotatably connected with a connecting member that is fixedly connected to the corresponding sliding member.

6. The temperature- and speed-controlled multi-groove section staining apparatus according to claim 5, characterized in that: A drive chamber communicating with the installation chamber is provided on one side of the main body of the device. A drive motor is provided inside the drive chamber. An eccentric component is fixedly connected to the output shaft of the drive motor. An adjustment groove is provided inside the eccentric component. An isolation plate is fixedly connected inside the adjustment groove. The isolation plate can divide the adjustment groove into a first chamber and a second chamber. An adjustment screw is rotatably connected inside the isolation plate. One end of the adjustment screw is rotatably connected to the inner wall of the second chamber. The other end of the adjustment screw is located inside the first chamber and is fixedly connected to a first gear. A movable component that is slidably connected to the inner wall of the second chamber is rotatably connected to the outer wall of the adjustment screw.

7. The temperature- and speed-controlled multi-groove section staining apparatus according to claim 6, characterized in that: Each of the aforementioned installation chambers is equipped with a sealing plate. The sealing plate located on one side of the drive motor is equipped with an adjusting motor concentric with the output shaft of the drive motor. The output shaft of the adjusting motor passes through the sealing plate and is fixedly connected to a transition shaft. The outer wall of the other end of the transition shaft is fixedly connected to a fixing member. A third chamber is opened inside the fixing member. An electromagnet is fixedly connected inside the third chamber. A magnet is slidably connected inside the third chamber. The magnetic poles of the magnet and the electromagnet on the opposite side are arranged in the same order. The end of the magnet away from the electromagnet is fixedly connected to an adjusting shaft that passes through the fixing member. The other end of the adjusting shaft is located inside the first chamber and is fixedly connected to a second gear.

8. The temperature- and speed-controlled multi-groove section staining apparatus according to claim 7, characterized in that: The second gear can mesh with the first gear. When the electromagnet is energized, the magnetic force generated by the electromagnet can cause the magnet to move away from the electromagnet, allowing the second gear to enter the first chamber and mesh with the first gear. At this time, the driving adjustment motor can be used to adjust the position of the moving part.

9. The temperature- and speed-controlled multi-groove section staining apparatus according to claim 8, characterized in that: The movable component is rotatably connected to a drive rod that is rotatably connected to the connector. A synchronizing rod is connected between the connectors on one side. When the drive motor rotates, it can drive multiple connectors to move synchronously through the drive rod and the synchronizing rod.

10. The temperature- and speed-controlled multi-groove section staining apparatus according to claim 1, characterized in that: The main body of the device is also equipped with oxygen supply equipment and a control panel.

Citation Information

Patent Citations

  • Specimen section dyeing equipment for pathology department

    CN117538128A