Prebiotic micro-ecological balance soothing essence, preparation method and hygienic product

Abstract

The invention discloses a prebiotic micro-ecological balance soothing essence, a preparation method and a hygienic product, the essence is prepared from micromolecule oat beta glucan, lactic acid, potassium lactate, butanediol, sodium hyaluronate, panthenol, a solubilizer, a non-irritant preservative composition and pure water according to specific weight percentage, the pH is strictly controlled to be 4.2 + / -0.1, and the essence has the advantages of no side effect, no side effect, no toxic or side effect, no side effect, no side effect and the like. According to the preparation method, synergistic fusion of raw materials is realized through step-by-step heating dissolution and cooling mixing; the essence can be prepared into a hygienic product containing the essence by coating and dipping a fiber layer or spraying the specific position of the hygienic product, can also be applied to wash supplies such as wet tissue base liquid and antibacterial lotion, maintains the micro-ecological balance of the vulva through double mechanisms of'acid environment regulation and prebiotic supply ', has the characteristics of soothing, repairing, reinforcing a barrier and being free of irritation, and has a good application prospect. Discomfort such as redness and swelling, pain and itching caused by using hygienic products by women can be effectively improved, and the application scene is wide.

Description

Technical Field

[0001] This invention relates to a hygiene product, specifically a prebiotic microecological balancing and soothing essence, its preparation method, and the hygiene product itself. Background Technology

[0002] When a woman's vulva is in prolonged contact with disposable hygiene products (such as sanitary napkins, panty liners, and sanitary underwear), the product's lack of breathability can create a damp and stuffy environment, leading to discomfort such as vulvar redness, swelling, pain, and itching. Furthermore, traditional disposable hygiene products often contain chemical antibacterial ingredients or irritating additives, which, with prolonged contact, can damage the vulvar skin's natural barrier, trigger allergic reactions, and even disrupt the local microecological balance—harmful bacteria (such as Escherichia coli and Staphylococcus aureus) proliferate in a neutral / alkaline environment, while beneficial bacteria (such as lactobacilli) are inhibited, ultimately leading to inflammation and severely impacting women's quality of life. Summary of the Invention

[0003] In order to overcome the shortcomings of the prior art, the present invention provides a prebiotic microecological balancing soothing essence, a preparation method and a hygiene product.

[0004] The technical solution adopted by this invention to solve its technical problem is: A prebiotic microecological balancing and soothing essence is made from the following raw materials in weight percentages: 0.01-10 parts of small molecule oat β-glucan, 0.01-10 parts of lactic acid, 0.01-10 parts of potassium lactate, 0.01-20.0 parts of butylene glycol, 0.01-2.0 parts of sodium hyaluronate, 0.01-5 parts of panthenol, 0.01-10 parts of solubilizer, 0.01-2.0 parts of non-irritating preservative composition, and 31-99.92 parts of pure water. The pH value of the essence is controlled at 4.2±0.1.

[0005] The non-irritating preservative composition is a mixture of capryloyl hydroxamic acid, glyceryl caprylate, and p-hydroxyacetophenone.

[0006] A method for preparing a prebiotic microecological balancing and soothing essence includes the following steps: S1: Mix butanediol and p-hydroxyacetophenone evenly, heat to 50-60℃ while stirring and keep warm for 5 minutes until the material is completely dissolved and the appearance is clear and transparent. S2: Cool the material obtained in step S1 to below 40°C, add solubilizer, octanoyl hydroxamic acid and glyceryl caprylate, and stir until uniform; S3: Add pure water, small molecule oat β-glucan, sodium hyaluronate, panthenol, lactic acid, and potassium lactate to the materials obtained in step S2 one by one, and stir and mix at 50-60 rpm for 15-20 minutes to obtain the prebiotic microecological balancing and soothing essence.

[0007] A prebiotic microecological balancing and soothing essence is a sanitary product. The prebiotic microecological balancing and soothing essence prepared by the above-mentioned preparation method can be prepared by any of the following methods: Method 1: The prebiotic microecological balancing and soothing essence is coated onto the fiber layer, dried and shaped, and then slit, pulled and rolled to obtain a fiber layer containing the prebiotic microecological balancing and soothing essence; the fiber layer is applied to disposable sanitary products, which from top to bottom include a fiber layer, an absorbent layer and a leak-proof layer; Method 2: Spray the prebiotic microecological balancing and soothing essence directly onto specific positions of the fiber layer of disposable sanitary products, and then dry and encapsulate it to form the disposable sanitary products. An application of a prebiotic microecological balancing and soothing essence, wherein the prebiotic microecological balancing and soothing essence is applied to disposable hygiene products or personal care products; the disposable hygiene products include sanitary napkins, panty liners, and sanitary underwear; the personal care products include wet wipe base liquid, antibacterial wash liquid, and antibacterial gel.

[0008] The beneficial effects of this invention are: 1. The serum uses lactic acid to strictly control the pH at 4.2±0.1. This acidic environment can significantly inhibit the growth of harmful bacteria such as Escherichia coli and Staphylococcus aureus, while providing suitable living conditions for beneficial bacteria such as lactic acid bacteria. Combined with small molecule oat β-glucan, it provides energy for beneficial bacteria, promotes their growth, reproduction and metabolism, and forms a dual microecological regulation mechanism of "inhibiting harmful bacteria + promoting beneficial bacteria", reducing the causes of inflammation from the root.

[0009] 2. Butylene glycol and sodium hyaluronate can improve skin elasticity and provide moisturizing effects, enhance the skin barrier function, and protect the skin from damage from the external environment. Panthenol can reduce skin sensitivity, reduce skin discomfort, relieve itching, and reduce stinging and burning sensations.

[0010] 3. Disposable hygiene products made with this essence can maintain the balance of the microecological flora, soothe and repair the skin. When used externally, these products can provide skincare benefits, effectively inhibiting harmful bacteria and promoting beneficial bacteria. They achieve multiple skincare mechanisms, including microecological defense and skin barrier strengthening, leaving the skin hydrated and firm, and building a natural biological protective film on the skin surface. Detailed Implementation

[0011] To make the objectives, technical solutions, and advantages of this invention clearer, the invention will be further described in detail below with reference to specific embodiments. It should be noted that, unless otherwise specified, the embodiments and features described herein can be combined with each other.

[0012] It should be understood that these descriptions are merely exemplary and are not intended to limit the scope of this invention.

[0013] A prebiotic microecological balancing and soothing essence is made from the following raw materials in weight percentages: 0.01-10 parts of small molecule oat β-glucan, 0.01-10 parts of lactic acid, 0.01-10 parts of potassium lactate, 0.01-20.0 parts of butylene glycol, 0.01-2.0 parts of sodium hyaluronate, 0.01-5 parts of panthenol, 0.01-10 parts of solubilizer, 0.01-2.0 parts of non-irritating preservative composition, and 31-99.92 parts of pure water. The non-irritating preservative composition is a mixture of capryloyl hydroxamic acid, glyceryl caprylate, and p-hydroxyacetophenone. The pH value of the essence is controlled at 4.2±0.1.

[0014] In this application, the small molecule oat β-glucan is selected as FM035-small molecule oat β-glucan, the lactic acid is selected as PURAC® Sanilac80, the potassium lactate is PURAC® BFP / 41, the solubilizer is Solubilisant LRI, and the non-irritating preservative composition is NAGO® A91 (capryloyl hydroxamic acid, glyceryl caprylate) and EverGuard HP p-hydroxyacetophenone.

[0015] The serum maintains a strictly controlled pH of 4.2±0.1 using lactic acid and potassium lactate. This acidic environment significantly inhibits the growth of harmful bacteria such as Escherichia coli and Staphylococcus aureus, while providing suitable conditions for the survival of beneficial bacteria such as lactic acid bacteria. Combined with small-molecule oat β-glucan, it provides energy for beneficial bacteria, promoting their growth, reproduction, and metabolism, forming a dual microecological regulation mechanism of "inhibiting harmful bacteria + promoting beneficial bacteria," thereby reducing inflammatory triggers from the root.

[0016] Butylene glycol and sodium hyaluronate can improve skin elasticity and provide moisturizing effects, enhance the skin barrier function, and protect the skin from external environmental damage. Panthenol can reduce skin sensitivity, reduce skin discomfort, relieve itching, and reduce stinging and burning sensations.

[0017] A method for preparing a prebiotic microecological balancing and soothing essence includes the following steps: S1: Mix butanediol and p-hydroxyacetophenone evenly, heat to 50-60℃ while stirring and keep warm for 5 minutes until the material is completely dissolved and the appearance is clear and transparent. S2: Cool the material obtained in step S1 to below 40°C, add solubilizer, octanoyl hydroxamic acid and glyceryl caprylate, and stir until uniform; S3: Add pure water, small molecule oat β-glucan, sodium hyaluronate, panthenol, lactic acid, and potassium lactate to the materials obtained in step S2 one by one, and stir and mix at 50-60 rpm for 15-20 minutes to obtain the prebiotic microecological balancing and soothing essence.

[0018] A prebiotic microecological balancing and soothing essence is a sanitary product. The prebiotic microecological balancing and soothing essence prepared by the above-mentioned preparation method can be prepared by any of the following methods: Method 1: The prebiotic microecological balancing and soothing essence is coated onto the fiber layer, dried and shaped, and then slit, pulled and rolled to obtain a fiber layer containing the prebiotic microecological balancing and soothing essence; the fiber layer is applied to disposable sanitary products, which from top to bottom include a fiber layer, an absorbent layer and a leak-proof layer; Method 2: Spray the prebiotic microecological balancing and soothing essence directly onto specific positions of the fiber layer of disposable sanitary products, and then dry and encapsulate it to form the disposable sanitary products. An application of a prebiotic microecological balancing and soothing essence, wherein the prebiotic microecological balancing and soothing essence is applied to disposable hygiene products or personal care products; the disposable hygiene products include sanitary napkins, panty liners, sanitary underwear, etc.; the personal care products include wet wipe base liquid, antibacterial wash liquid, antibacterial gel, etc.

[0019] Disposable hygiene products made with this essence can maintain the balance of the microecological flora, soothe and repair the skin. When applied topically to the skin, these products provide skincare benefits, effectively inhibiting harmful bacteria and promoting beneficial bacteria. They achieve multiple skincare mechanisms, including microecological defense and skin barrier strengthening, leaving the skin hydrated and firm, and building a natural biological protective film on the skin's surface.

[0020] The antibacterial efficacy of the prebiotic microecological balancing and soothing essence, according to a third-party testing report, is as follows: Under the experimental conditions, the inhibition rates of the sample against Staphylococcus aureus at 4h, 8h, and 12h were 94.3%, 98.6%, and 99.9%, respectively; against Escherichia coli, 92.2%, 97.5%, and 99.8%, respectively; and against Candida albicans, 92.6%, 97.5%, and 99.7%, respectively. This indicates that the prebiotic microecological balancing and soothing essence has an inhibitory effect on harmful bacteria.

[0021] The probiotic microecological balancing and soothing essence's antibacterial effects, according to a third-party testing report, are as follows: Under the experimental conditions, the growth promotion rates of the sample against *Lactobacillus curvatureii* at 4h, 8h, and 12h were 75.0%, 115.4%, and 176.5%, respectively; against *Lactobacillus gasseri* at 68.2%, 120.8%, and 180.0%, respectively; and against *Lactobacillus rhamnosus* at 70.4%, 131.9%, and 162.1%, respectively. This indicates that the prebiotic microecological balancing and soothing essence has a growth-promoting effect on beneficial bacteria.

[0022] The soothing effects of the prebiotic microecological balancing and soothing essence are as follows, according to a third-party testing report: Macrophages can be used as a cell model to study the inhibition of inflammatory factor IL-6 levels by cosmetics. By stimulating with bacterial lipopolysaccharide (LPS), the levels of inflammatory factor IL-6 in the negative control and experimental sample groups were measured to evaluate whether the experimental samples were effective in inhibiting the levels of inflammatory factor IL-6. The IL-6 levels were measured using enzyme-linked immunosorbent assay (ELISA).

[0023] The prebiotic microecological balancing and soothing essence samples showed high cell activity at concentrations of 0.5% and 1.0%, with cellular IL-6 inflammatory factor content at 98.38% and 94.19% of the negative control group, respectively. The 0.5% and 1.0% samples showed significant effects in inhibiting cellular IL-6 inflammatory factor content (P<0.05), indicating that the samples at concentrations of 0.5% and 1.0% significantly inhibited cellular IL-6 inflammatory factor content, suggesting that the samples have a certain soothing effect.

[0024] The repairing effects of the prebiotic microecological balancing and soothing essence are as follows, according to a third-party testing report: When trauma occurs, fibroblasts are regulated by cytokines and the extracellular matrix, rapidly proliferating and migrating, forming granulation tissue to fill the wound, secreting collagen, and ultimately participating in scar formation. Fibroblasts can be used as a cell model to study the repair capabilities of cosmetics. By comparing the degree of scratch healing of fibroblasts after administration of the test substance with that of the negative control and the test substance, the efficacy of the test substance in repair can be evaluated.

[0025] In the positive control, fibroblast scratches were completely healed after 24 hours, with a healing rate of 85.66%. In the negative control, the degree of healing of fibroblast scratches was lower after 24 hours, with a healing rate of 21.96%. When the concentrations of the prebiotic microecological balancing soothing essence were 0.25% and 0.5%, cell activity was high, and the healing rates of fibroblast scratches after 24 hours were 34.70% and 32.57%, respectively. The samples with concentrations of 0.25% and 0.5% promoted the healing of fibroblast scratches, indicating that the samples had a repairing effect.

[0026] Volunteer usage test: Volunteers were recruited from the gynecology clinic of a hospital. The recruitment criteria for volunteers were: having sensitive genital area. A total of 100 female volunteers were recruited and randomly divided into 2 groups of 50 each, namely test group 1 and test group 2. Test group 1 used sanitary napkins made with prebiotic microecological balancing and soothing essence, while test group 2 used antibacterial sanitary napkins (panty liners) and sanitary panties from a foreign brand. The number of samples was calculated based on three months of menstrual period.

[0027] In this test, all sanitary napkins (panty liners) and sanitary panties used had their labels and other identifying materials removed, so the volunteers did not know what kind of sanitary napkins (panty liners) and sanitary panties they were using. After their menstrual period, the volunteers were required to provide the experimenters with their experience of using the products, including: whether the vulva felt clean and refreshed, whether the vagina felt sore or itchy, whether the discharge was reduced, whether it alleviated menstrual discomfort, and whether there was any friction against the sanitary pads. Each item was scored out of 10, with higher scores for better feelings. The average score for each group of volunteers was calculated over three menstrual periods over three months.

[0028] Test results show that test group 1, which uses sanitary napkins (panty liners) and sanitary panties containing prebiotic microecological balancing soothing essence, is significantly better than test group 2 in terms of vaginal freshness, relief from itching, relief from menstrual discomfort, and reduction of friction with the sanitary pad. Therefore, it can be concluded that sanitary napkins (panty liners) and sanitary panties made with prebiotic microecological balancing soothing essence have their nutrients absorbed by the vulvar skin during use, which can enhance skin cell vitality and relieve symptoms such as vulvar inflammation. After use, they have a silky feel and achieve the purpose of nourishing the skin and balancing the skin's microecology.

[0029] In this invention, the term "a plurality of" refers to two or more unless otherwise expressly defined. The term "and / or" as used herein includes any and all combinations of one or more of the associated listed items. The terms "installation," "connection," "linking," "fixing," etc., should be interpreted broadly. For example, "connection" can be a fixed connection, a detachable connection, or an integral connection; "linking" can be a direct connection or an indirect connection via an intermediate medium. Those skilled in the art will understand the specific meaning of the above terms in this invention according to the specific circumstances.

[0030] It should be noted that when a component is referred to as being "assembled on," "mounted on," "fixed to," or "set on" another component, it can be directly on the other component or there may be an intermediate component. When a component is considered to be "connected to" another component, it can be directly connected to the other component or there may be an intermediate component present. The terms "vertical," "horizontal," "upper," "lower," "left," "right," and similar expressions used herein are for illustrative purposes only and do not represent the only possible implementation.

[0031] In the description of this specification, the terms "one embodiment," "some embodiments," "specific embodiment," etc., refer to a specific feature, structure, material, or characteristic described in connection with that embodiment or example, which is included in at least one embodiment or example of the present invention. In this specification, the illustrative expressions of the above terms do not necessarily refer to the same embodiment or example. Furthermore, the specific features, structures, materials, or characteristics described may be combined in any suitable manner in one or more embodiments or examples.

[0032] Although embodiments of the invention have been shown and described, those skilled in the art will understand that various changes, modifications, substitutions and alterations can be made to these embodiments without departing from the principles and spirit of the invention, the scope of which is defined by the claims and their equivalents.

Claims

1. A prebiotic microecological balancing and soothing essence, characterized in that, It is made from the following raw materials in weight percentage: 0.01-10 parts of small molecule oat β-glucan, 0.01-10 parts of lactic acid, 0.01-10 parts of potassium lactate, 0.01-20.0 parts of butylene glycol, 0.01-2.0 parts of sodium hyaluronate, 0.01-5 parts of panthenol, 0.01-10 parts of solubilizer, 0.01-2.0 parts of non-irritating preservative composition, and 31-99.92 parts of pure water. The pH value of the essence is controlled at 4.2±0.

1.

2. The prebiotic microecological balancing and soothing essence according to claim 1, characterized in that... The non-irritating preservative composition is a mixture of capryloyl hydroxamic acid, glyceryl caprylate, and p-hydroxyacetophenone.

3. A method for preparing a prebiotic microecological balancing and soothing essence, characterized in that, Includes the following steps: S1: Mix butanediol and p-hydroxyacetophenone evenly, heat to 50-60℃ while stirring and keep warm for 5 minutes until the material is completely dissolved and the appearance is clear and transparent. S2: Cool the material obtained in step S1 to below 40°C, add solubilizer, octanoyl hydroxamic acid and glyceryl caprylate, and stir until uniform; S3: Add pure water, small molecule oat β-glucan, sodium hyaluronate, panthenol, lactic acid, and potassium lactate to the materials obtained in step S2 one by one, and stir and mix at 50-60 rpm for 15-20 minutes to obtain the prebiotic microecological balancing and soothing essence.

4. A sanitary product containing a prebiotic microecological balancing and soothing essence, characterized in that, The prebiotic microecological balancing and soothing essence prepared by the preparation method described in claim 3 can be prepared by any of the following methods: Method 1: The prebiotic microecological balancing and soothing essence is coated onto the fiber layer, dried and shaped, and then slit, pulled and rolled to obtain a fiber layer containing the prebiotic microecological balancing and soothing essence; the fiber layer is applied to disposable sanitary products, which from top to bottom include a fiber layer, an absorbent layer and a leak-proof layer; Method 2: Spray the prebiotic microecological balancing and soothing essence directly onto specific positions of the fiber layer of disposable sanitary products, and then dry and encapsulate it to form the disposable sanitary products. An application of a prebiotic microecological balancing and soothing essence, characterized in that, The prebiotic microecological balancing and soothing essence is applied to disposable hygiene products or personal care products; the disposable hygiene products include sanitary napkins, panty liners, and sanitary underwear; the personal care products include wet wipe base liquid, antibacterial wash liquid, and antibacterial gel.