Specific protein analyzer

Abstract

The invention relates to the technical field of in-vitro diagnostic instruments, in particular to a specific protein analyzer which comprises a machine body and a sample shaking mechanism, the sample shaking-up mechanism comprises a supporting frame, a longitudinal linear motion module, a connecting plate, a transmission guide rail, a lifting plate, a rotating shaft, two test tube clamps, a driven shifting piece, a stainless steel bearing, a rotating piece, a mixing rod, a synchronous rod, a guide block and a closing module, and a shaking-up groove is formed in the side edge of the guide block; when a certain test tube needs to be sampled, the closing module drives the test tube clamps to stably clamp the sampled test tube, the longitudinal linear motion module drives the lifting plate to ascend and descend along the transmission guide rail, at the moment, the stainless steel bearing moves back and forth in the shaking-up groove, the two test tube clamps swing to shake up the sample, and therefore the condensed or uneven sample can be shaken up. Manual treatment is not needed, the working efficiency is improved, and the labor cost is reduced.

Description

Technical Field

[0001] This invention relates to the field of in vitro diagnostic instruments, and more particularly to a specific protein analyzer. Background Technology

[0002] In the field of in vitro diagnostics, the commonly used method for detecting the concentration of specific proteins is immunoturbidimetry. Its basic principle is that after the reagent and sample are mixed and reacted, the turbidity changes, and the concentration of the specific protein in the sample can be obtained by optically detecting the change in turbidity. The detection process requires adding the reagent and sample to the reaction apparatus and mixing thoroughly before using an optical detection module to acquire data.

[0003] Currently, there are semi-automatic and fully automatic specific protein analyzers. However, both semi-automatic and fully automatic specific protein analyzers require manual shaking of the sample tubes beforehand. The purpose of this process is to shake the coagulated or uneven sample before adding the reagents and sample to the reaction device for mixing. Manually shaking the sample tubes is inefficient and has high labor costs. Summary of the Invention

[0004] The purpose of this invention is to provide a specific protein analyzer that can shake agglomerated or uneven samples to achieve uniformity without manual processing, thereby improving work efficiency and reducing labor costs.

[0005] To achieve the above objectives, the present invention provides a specific protein analyzer, including a body and a sample mixing mechanism. The sample mixing mechanism includes a support frame, a longitudinal linear motion module, a connecting plate, a transmission guide rail, a lifting plate, a rotating shaft, two test tube clamps, a driven lever, a stainless steel bearing, a rotating plate, a mixing rod, a synchronization rod, a guide block, and a closing module.

[0006] The support frame is fixedly connected to the inside of the machine body. The longitudinal linear motion module is located on the side of the support frame. The connecting plate is located on the side of the longitudinal linear motion module. The transmission guide rail is fixedly connected to the side of the support frame. The lifting plate is slidably connected to the transmission guide rail and is located on the side of the transmission guide rail. The rotating shaft is rotatably connected to the lifting plate and is located on the side of the lifting plate. The two test tube clamps are sleeved on the side of the rotating shaft. The driven lever is rotatably connected to the rotating shaft and is located at one end of the rotating shaft. The inner ring of the stainless steel bearing is fixedly connected to the driven lever and is located on the side of the driven lever. The rotating plate is fixedly connected to the side of the driven lever. One end of the mixing rod is fixedly connected to the rotating plate, and the other end of the mixing rod passes through one of the test tube clamps. The synchronizing rod is located between the two test tube clamps. The guide block is fixedly connected to the side of the support frame. The guide block has a shaking groove on its side, and the stainless steel bearing is located in the shaking groove. The closing module is located on the two test tube clamps.

[0007] The longitudinal linear motion module includes multiple first synchronous pulleys, a transmission belt, and a lifting motor; the multiple first synchronous pulleys are rotatably connected to the support frame and are located on the side of the support frame; the transmission belt is sleeved on the side of the multiple first synchronous pulleys; the lifting motor is fixedly connected to the side of the support frame, and the output end of the lifting motor is fixedly connected to the first synchronous pulley.

[0008] The closed module includes two second synchronous pulleys, a synchronous belt, a first clamping plate, a second clamping plate, a first lead screw motor, and a docking plate. The two second synchronous pulleys are rotatably connected to the lifting plate and are located on the sides of the lifting plate. The synchronous belt is sleeved on the sides of the two second synchronous pulleys. One end of the first clamping plate is fixedly connected to the synchronous belt, and the other end is on the rotating shaft. One end of the second clamping plate is fixedly connected to the synchronous belt, and the other end is on the rotating shaft. The first lead screw motor is fixedly connected to the side of the lifting plate. The docking plate is fixedly connected to the lead screw of the first lead screw motor and to the first clamping plate, and is located on the side of the first clamping plate.

[0009] The specific protein analyzer also includes an electric linear module and a transfer chamber; the electric linear module is located inside the main body, and the transfer chamber is located on the side of the electric linear module.

[0010] The specific protein analyzer further includes a sampling mechanism, which comprises a horizontal linear motion module, a vertical guide rail, a second lead screw motor, a slider, a fixed base, a limiting plate, a compression spring, a sampling needle, a positioning optocoupler, a liquid level sensing device, a positioning component, and a mixing device. The horizontal linear motion module is disposed inside the main body. The vertical guide rail is disposed on the side of the horizontal linear motion module. The second lead screw motor is fixedly connected to the side of the vertical guide rail. The slider is disposed on the second lead screw motor and slidably connected to the vertical guide rail. The fixed base is fixedly connected to the side of the slider. The limiting plate is fixedly connected to the side of the slider. The compression spring is fixedly connected to the side of the limiting plate. The sampling needle is fixedly connected to the side of the compression spring and passes through the fixed base. The positioning optocoupler is fixedly connected to the side of the vertical guide rail. The liquid level sensing device is fixedly connected to the side of the slider. The positioning component is disposed at the bottom of the horizontal linear motion module and has a positioning groove. The mixing device is disposed between the vertical guide rail and the sampling needle.

[0011] The specific protein analyzer further includes a reagent low-temperature storage mechanism, which comprises a base plate, a heat sink, multiple heat dissipation blocks, a reagent tray, a temperature sensor, a pallet, a rotating module, a Peltier, a heat-conducting plate, an air duct, a cooling fan, and an RFID device. The base plate is fixedly connected to the inside of the main body, the heat sink is fixedly connected to the top of the base plate, and the multiple heat dissipation blocks are respectively fixedly connected to one side of the heat sink. The reagent tray is fixedly connected to the top of the heat sink, and the top of the reagent tray has a sampling hole. The temperature sensor is fixedly connected to the side of the reagent tray. The pallet and the reagent tray are rotatably connected and located inside the reagent tray. The rotating module is disposed between the base plate and the pallet. The Peltier is fixedly connected to the top of the heat sink, and the heat-conducting plate is fixedly connected between the Peltier and the reagent tray. The air duct is fixedly connected to the side of the heat sink. The cooling fan is fixedly connected to the side of the air duct. The RFID device is fixedly connected to the side of the reagent tray.

[0012] The specific protein analyzer further includes a multi-source optical detection mechanism, which includes a mounting base, a reaction cup, a first light source, a second light source, a third light source, an angle receiver, and an angle receiver. The mounting base is fixedly connected to the inside of the main body, the reaction cup is fixedly connected to the inner side of the mounting base, the first light source is fixedly connected to the side of the mounting base, the second light source is fixedly connected to the side of the mounting base, the third light source is fixedly connected to the side of the mounting base, the first angle receiver is fixedly connected to the side of the mounting base, and the second angle receiver is fixedly connected to the side of the mounting base.

[0013] In a specific protein analyzer of the present invention, when a test tube needs to be sampled, the sample injection mechanism conveys it to the area below the test tube clamp. The closing module drives the two test tube clamps to open, and the longitudinal linear motion module drives the lifting plate to fall along the transmission guide rail, so that the test tube clamp reaches the test tube retrieval point. Subsequently, the closing module drives the test tube clamp to hold the sampling test tube firmly. The longitudinal linear motion module drives the lifting plate to rise along the transmission guide rail. When it rises to the point where the stainless steel bearing enters the shaking groove in the guide block, the test tube clamp is driven to tilt to the right. The longitudinal linear motion module lowers the lifting plate along the transmission guide rail, and the guide wheel leaves the guide block. The above steps are repeated, and the sampling test tube held by the test tube clamp is shaken. When the stainless steel bearing moves back and forth in the mixing tank, the driven paddle and the rotating paddle will swing back and forth. The rotating paddle drives the two test tube clamps to swing simultaneously through the mixing rod and the synchronizing rod, thereby achieving the mixing of the sample. In this way, agglomerated or uneven samples can be mixed without manual processing, which improves work efficiency and reduces labor costs. Attached Figure Description

[0014] To more clearly illustrate the technical solutions in the embodiments of this application or the prior art, the accompanying drawings used in the description of the embodiments or the prior art will be briefly introduced below.

[0015] Figure 1 This is a schematic diagram of the overall structure of the specific protein analyzer of the present invention.

[0016] Figure 2 This is a schematic diagram of the internal structure of a specific protein analyzer according to the present invention.

[0017] Figure 3 This is a schematic diagram of the electric linear module and transfer compartment of the present invention.

[0018] Figure 4 This is a schematic diagram of the sample shaking mechanism of the present invention.

[0019] Figure 5 yes Figure 4 A magnified view of detail A.

[0020] Figure 6 This is a schematic diagram of the internal structure of the sample shaking mechanism of the present invention.

[0021] Figure 7 This is a schematic diagram of the guide block of the present invention.

[0022] Figure 8 This is a schematic diagram of the sampling mechanism of the present invention.

[0023] Figure 9This is a schematic diagram of the structure of the vertical guide rail, the second lead screw motor, the slider, the fixed seat, the limiting plate, the compression spring, the sampling needle, and the mixing device of the present invention.

[0024] Figure 10 This is a cross-sectional view of the vertical guide rail, the second lead screw motor, the slider, the fixed seat, the limiting plate, the compression spring, the sampling needle, and the mixing device of the present invention.

[0025] Figure 11 yes Figure 10 A magnified view of detail B.

[0026] Figure 12 This is a schematic diagram of the reagent low-temperature storage mechanism of the present invention.

[0027] Figure 13 This is a schematic diagram of the reagent low-temperature storage mechanism of the present invention from another perspective.

[0028] Figure 14 This is a cross-sectional view of the reagent low-temperature storage mechanism of the present invention.

[0029] Figure 15 This is a schematic diagram of the structure of the multi-source optical detection mechanism of the present invention.

[0030] Figure 16 This is a control block diagram of a specific protein analyzer according to the present invention.

[0031] 1-Main body, 2-Sample shaking mechanism, 3-Support frame, 4-Longitudinal linear motion module, 5-Connecting plate, 6-Transmission guide rail, 7-Lifting plate, 8-Rotating shaft, 9-Test tube clamp, 10-Driven lever, 11-Stainless steel bearing, 12-Rotating plate, 13-Mixing rod, 14-Synchronizing rod, 15-Guide block, 16-Closed module, 17-Shaking groove, 18-First synchronous pulley, 19-Transmission belt, 20-Lifting motor, 21-Second synchronous pulley, 22-Synchronizing belt, 23-First clamping plate, 24-Second clamping plate, 25-First lead screw motor, 26-Dating plate, 27-Electric linear module, 28-Transfer compartment, 29-Sampling mechanism, 30-Horizontal linear motion module, 31-Vertical guide rail, 32-Second lead screw motor 33-Slider, 34-Fixed base, 35-Limiting plate, 36-Compression spring, 37-Sampling needle, 38-Positioning optocoupler, 39-Liquid level sensing device, 40-Positioning component, 41-Mixing device, 42-Reagent low-temperature storage mechanism, 43-Base plate, 44-Heat sink, 45-Heat block, 46-Reagent tray, 47-Temperature sensor, 48-Tray, 49-Rotating module, 50-Peltier, 51-Heat-conducting plate, 52-Air duct, 53-Cooling fan, 54-Radio frequency identification device, 55-Sampling hole, 56-Multi-source optical detection mechanism, 57-Mounting base, 58-Reaction cup, 59-Light source one, 60-Light source two, 61-Light source three, 62-Angle receiver one, 63-Angle receiver two, 64-Positioning groove. Detailed Implementation

[0032] The embodiments of the present invention are described in detail below. Examples of the embodiments are shown in the accompanying drawings. The embodiments described below with reference to the accompanying drawings are exemplary and intended to explain the present invention, but should not be construed as limiting the present invention.

[0033] Please see Figures 1-16This invention provides a specific protein analyzer, comprising a body 1, a sample mixing mechanism 2, an electric linear module 27, a transfer chamber 28, a sampling mechanism 29, a reagent low-temperature storage mechanism 42, and a multi-source optical detection mechanism 56. The sample mixing mechanism 2 includes a support frame 3, a longitudinal linear motion module 4, a connecting plate 5, a transmission guide rail 6, a lifting plate 7, a rotating shaft 8, two test tube clamps 9, a driven lever 10, a stainless steel bearing 11, a rotating plate 12, a mixing rod 13, a synchronization rod 14, a guide block 15, and a closing module 16. The longitudinal linear motion module 4 includes multiple first synchronization pulleys 18, a transmission belt 19, and a lifting motor 20. The closing module 16 includes two second synchronization pulleys 21, a synchronization belt 22, a first clamping plate 23, a second clamping plate 24, a first lead screw motor 25, and a docking plate 26. The sampling mechanism 29 includes a horizontal linear... The linear motion module 30, vertical guide rail 31, second lead screw motor 32, slider 33, fixed seat 34, limiting plate 35, compression spring 36, sampling needle 37, positioning optocoupler 38, liquid level sensing device 39, positioning component 40, and mixing device 41 are included. The reagent low-temperature storage mechanism 42 includes a base plate 43, heat sink 44, multiple heat sink blocks 45, reagent tray 46, temperature sensor 47, tray 48, rotating module 49, Peltier 50, heat-conducting plate 51, air duct 52, cooling fan 53, and radio frequency identification device 54. The multi-source optical detection mechanism 56 includes a mounting base 57, reaction cup 58, light source one 59, light source two 60, light source three 61, angle receiver one 62, and angle receiver two 63. The aforementioned scheme can shake agglomerated or uneven samples evenly without manual processing, improving work efficiency and reducing labor costs.

[0034] In this specific embodiment, the support frame 3 is fixedly connected to the inside of the machine body 1; the longitudinal linear motion module 4 is disposed on the side of the support frame 3; the connecting plate 5 is disposed on the side of the longitudinal linear motion module 4; and the transmission guide rail 6 is fixedly connected to the side of the support frame 3. The lifting plate 7 is slidably connected to the transmission guide rail 6 and is located on the side of the transmission guide rail 6. The rotating shaft 8 is rotatably connected to the lifting plate 7 and is located on the side of the lifting plate 7. Two test tube clamps 9 are sleeved on the side of the rotating shaft 8. The driven lever 10 is rotatably connected to the rotating shaft 8 and is located at one end of the rotating shaft 8. The inner ring of the stainless steel bearing 11 is fixedly connected to the driven lever 10 and located on the side of the driven lever 10; the rotating plate 12 is fixedly connected to the side of the driven lever 10; one end of the mixing rod 13 is fixedly connected to the rotating plate 12, and the other end of the mixing rod 13 passes through one of the test tube clamps 9; the synchronizing rod 14 is disposed between the two test tube clamps 9; the guide block 15 is fixedly connected to the side of the support frame 3, and the side of the guide block 15 is provided with a shaking groove 17, in which the stainless steel bearing 11 is located; the closing module 16 is disposed on the two test tube clamps 9. Two strip-shaped grooves are provided on the test tube clamps 9 for the mixing rod 13 and the synchronizing rod 14 to pass through, respectively. One end of the synchronizing rod 14 is fixedly connected to one of the test tube clamps 9, and the other end of the synchronizing rod 14 passes through the other test tube clamp 9. When a test tube needs to be sampled, the sample injection mechanism delivers it to the area below the test tube clamp 9. The closing module 16 drives the two test tube clamps 9 to open, and the longitudinal linear motion module 4 drives the lifting plate 7 to fall along the transmission guide rail 6, so that the test tube clamp 9 reaches the sampling position. Then, the closing module 16 drives the test tube clamp 9 to hold the sampling test tube firmly. The longitudinal linear motion module 4 drives the lifting plate 7 to rise along the transmission guide rail 6. When it rises to the point where the stainless steel bearing 11 enters the shaking groove 17 in the guide block 15, the test tube clamp 9 is driven to tilt to the right. The longitudinal linear motion module 4 lowers the lifting plate 7 along the transmission guide rail 6, and the guide wheel leaves the guide block 15. The above steps are repeated, and the sampling test tube clamped by the test tube clamp 9 is shaken. When the stainless steel bearing 11 moves back and forth in the shaking groove 17, the driven paddle 10 and the rotating plate 12 will swing back and forth. The rotating plate 12 drives the two test tube clamps 9 to swing simultaneously through the mixing rod 13 and the synchronizing rod 14, thereby achieving the shaking of the sample. In this way, agglomerated or uneven samples can be shaken evenly without manual processing, which improves work efficiency and reduces labor costs.

[0035] In this configuration, multiple first synchronous pulleys 18 are rotatably connected to the support frame 3 and are located on the sides of the support frame 3. A transmission belt 19 is sleeved on the sides of the multiple first synchronous pulleys 18. A lifting motor 20 is fixedly connected to the side of the support frame 3, and the output end of the lifting motor 20 is fixedly connected to the first synchronous pulleys 18. The lifting motor 20 drives the first synchronous pulleys 18 to rotate, the first synchronous pulleys 18 drive the transmission belt 19 to move, and the transmission belt 19, via the connecting plate 5, drives the lifting plate 7 to rise and fall.

[0036] Secondly, the two second synchronous pulleys 21 are rotatably connected to the lifting plate 7 and are located on the side of the lifting plate 7 respectively; the synchronous belt 22 is sleeved on the side of the two second synchronous pulleys 21; one end of the first clamping plate 23 is fixedly connected to the synchronous belt 22, and the other end is on the rotating shaft 8; one end of the second clamping plate 24 is fixedly connected to the synchronous belt 22, and the other end is on the rotating shaft 8; the first lead screw motor 25 is fixedly connected to the side of the lifting plate 7; the docking plate 26 is fixedly connected to the lead screw of the first lead screw motor 25 and fixedly connected to the first clamping plate 23, and is located on the side of the first clamping plate 23. The first clamping plate 23 and the second clamping plate 24 have approximately U-shaped cross-sections. The two test tube clamps 9 are located inside the first clamping plate 23 and the second clamping plate 24, respectively. When the first lead screw motor 25 is activated, it drives the docking plate 26 and the first clamping plate 23 to move. The first clamping plate 23 drives the synchronous belt 22 to move, and the synchronous belt 22 drives the second clamping plate 24 to move. The first clamping plate 23 and the second clamping plate 24 simultaneously drive the two test tube clamps 9 to move. Thus, by controlling the first lead screw motor 25, the two test tube clamps 9 can be controlled to move closer or further apart to clamp and release the test tubes. The first lead screw motor 25 is a through-type linear lead screw stepper motor.

[0037] Meanwhile, the electric linear module 27 is disposed inside the body 1, and the transfer chamber 28 is disposed on the side of the electric linear module 27. The top of the transfer chamber 28 has a placement slot (test tube position) for placing sampling test tubes. The electric linear module 27 is used to drive the transfer chamber 28 to move horizontally. The electric linear module 27 is existing technology and can adopt the existing synchronous belt 22 linear module or the structure of the longitudinal linear motion module 4 of this application. After the sample test tubes are shaken evenly, the electric linear module 27 moves the transfer chamber 28 below the test tube clamp 9. The lifting motor 20 rotates, driving the transmission belt 19 to lower the lifting plate 7 along the transmission guide rail 6, placing the sampling test tubes into the test tube position of the transfer chamber 28. The first lead screw motor... The motor 25 rotates, causing the test tube clamp 9 to open and release the sampling test tube; then the lifting motor 20 rotates, driving the transmission belt 19 to raise the lifting plate 7 along the transmission guide rail 6, causing the test tube clamp 9 to detach from the sampling test tube; the transfer chamber 28 moves the sampling test tube into the sampling position for sampling; after sampling, the transfer chamber 28 returns the sampling test tube to below the test tube clamp 9, the lifting motor 20 rotates, driving the transmission belt 19 to lower the lifting plate 7 along the transmission guide rail 6, causing the test tube clamp 9 to fit onto the sampling test tube, and the clamping screw motor 25 rotates, causing the test tube clamp 9 to clamp tightly. Then, the lifting motor 20 rotates, causing the lifting plate 7 to rise along the transmission guide rail 6, and the test tube clamp 9 carries the sampling test tube away from the transfer chamber 28, and the transfer chamber 28 returns to the sampling position; finally, the lifting motor 20 rotates, driving the transmission belt 19 to lower the lifting plate 7 along the transmission guide rail 6, and put the sampling test tube back into the test tube rack.

[0038] Additionally, the horizontal linear motion module 30 is disposed inside the body 1; the vertical guide rail 31 is disposed on the side of the horizontal linear motion module 30; the second lead screw motor 32 is fixedly connected to the side of the vertical guide rail 31; the slider 33 is disposed on the second lead screw motor 32, and the slider 33 is slidably connected to the vertical guide rail 31; the fixed seat 34 is fixedly connected to the side of the slider 33; the limiting plate 35 is fixedly connected to the side of the slider 33; the compression spring 36 is fixedly connected to the side of the limiting plate 35; the sampling needle 37 is fixedly connected to the side of the compression spring 36, and the sampling needle 37 passes through the fixed seat 34; the positioning optocoupler 38 is fixedly connected to the side of the vertical guide rail 31; the liquid level sensing device 39 is fixedly connected to the side of the slider 33; the positioning member 40 is disposed at the bottom of the horizontal linear motion module 30, and the positioning member 40 is provided with a positioning groove 64; the mixing device 41 is disposed between the vertical guide rail 31 and the sampling needle 37. The horizontal linear motion module 30 is used to drive the transfer chamber 28 to move horizontally. The horizontal linear motion module 30 is existing technology and can adopt either the existing synchronous belt 22 linear module or the structure of the longitudinal linear motion module 4 of this application. The second lead screw motor 32 is a through-shaft lead screw stepper motor with an external nut, and the slider 33 is fixed to the external nut of the second lead screw motor 32. The transfer chamber 28 brings the sampling tube to the sampling position. The horizontal linear motion module 30 sends the sampling needle 37 above the sampling position. The positioning optocoupler 38 determines whether it is in the positioning slot 64 position. The second lead screw motor 32 rotates, and the sampling needle 37 is lowered into the sampling tube via the lead screw. The liquid level sensing device 39 determines whether there is a sample in the sampling tube. After the sampling needle 37 completes sampling, the second lead screw motor 32 rotates, and the sampling needle 37 is raised via the lead screw and the slider 33. Subsequently, the horizontal linear motion module 30 sends the sampling needle 37 above the reaction cup 58 position. The positioning optocoupler 38 determines whether it is in the positioning slot 64 position. Positioning groove 64; after the sampling needle 37 moves above the reaction cup 58, the second lead screw motor 32 rotates, lowering the sampling needle 37 into the reaction cup 58 via the lead screw; then the sampling needle 37 ejects the sample, and simultaneously the mixing device 41 drives the sampling needle 37 to rapidly swing and mix the sample and reagent; finally, the second lead screw motor 32 rotates, raising the sampling needle 37 via the lead screw, and the horizontal linear motion module 30 brings the sampling needle 37 back to its initial position; the mixing device 41 is prior art, for example, a sample constant speed mixing device with closed-loop control can be referred to in patent number 202510116676.5.

[0039] Furthermore, the base plate 43 is fixedly connected to the inside of the body 1, the heat sink 44 is fixedly connected to the top of the base plate 43, and multiple heat sink blocks 45 are respectively fixedly connected to one side of the heat sink 44; the reagent tray 46 is fixedly connected to the top of the heat sink 44, the top of the reagent tray 46 is provided with a sampling hole 55, and the temperature sensor 47 is fixedly connected to the side of the reagent tray 46; the tray 48 is rotatably connected to the reagent tray 46 and is located inside the reagent tray 46; the rotating module 49 is disposed between the base plate 43 and the tray 48; the Peltier 50 is fixedly connected to the top of the heat sink 44, and the heat-conducting plate 51 is fixedly connected between the Peltier 50 and the reagent tray 46; the air duct 52 is fixedly connected to the side of the heat sink 44; the cooling fan 53 is fixedly connected to the side of the air duct 52; and the radio frequency identification device 54 is fixedly connected to the side of the reagent tray 46. The reagent low-temperature storage mechanism 42 is used to keep the reagent tray 46 at a low temperature to prevent the reagent from deteriorating due to temperature. It also has radio frequency identification (RFID) function, which selects reagents by identifying the RFID card information of different reagent bottles. When the reagent low-temperature storage mechanism is working, it collects data from the temperature sensor 47 in real time and controls the Peltier 50 to work. The Peltier 50 is attached to the heat sink 44 on one side and the heat conduction plate 51 on the other side to achieve heat transfer. The air duct 52 and the heat sink 44 are hollow inside, and there is a gap between the adjacent heat sink blocks 45 to allow airflow. The cooling fan 53 works to send the heat from the heat conduction plate 51 and the heat sink blocks 45 to the outside of the instrument through the air duct 52. The reagent is placed on the tray 48. When the reagent is sampled, the rotation module 49 drives the tray 48 to rotate, moving the required reagent to the position below the sampling hole 55. The RFID device 54 identifies the reagent at the sampling position, and the sampling needle 37 samples the reagent. The rotation module 49 is used to drive the tray 48 to rotate, and existing technology can be used, such as a motor as the drive source.

[0040] Finally, the mounting base 57 is fixedly connected to the inside of the body 1, the reaction cup 58 is fixedly connected to the inside of the mounting base 57, the first light source 59 is fixedly connected to the side of the mounting base 57, the second light source 60 is fixedly connected to the side of the mounting base 57, the third light source 61 is fixedly connected to the side of the mounting base 57, the first angle receiver 62 is fixedly connected to the side of the mounting base 57, and the second angle receiver 63 is fixedly connected to the side of the mounting base 57. The sampling needle 37 mixes the sample and reagent in the reaction cup 58. Depending on the test item, the first light source, the second light source 60, or the third light source 61 is selected. The first angle receiver 62 and the second angle receiver 63 simultaneously receive data. After the reaction is completed, the degree of reactivity is calculated based on the received data, and then the concentration is obtained. The first angle receiver 62 and the second angle receiver 63 act as receivers for scattering and transmission, respectively, to detect changes in the receiver signal during the reaction of the mixture in the reaction cup 58. An automatic negative pressure liquid circuit system is installed inside the body 1 for liquid circuit cleaning and filling. The control unit (INC) of this specific protein analyzer mainly consists of an industrial control board and a display touch screen. It communicates with each module via CAN, sets and debugs the analyzer parameters, and controls the analyzer's operating status. By operating the instrument control unit (INC) through the touch screen, selecting the test item and clicking "start test", the instrument control unit (INC) begins to send control commands to each module. The automatic negative pressure liquid circuit system and the control unit are mature technologies in existing specific protein analyzers and are not within the scope of protection of this application. Their working principles will not be described in detail here.

[0041] When using this invention, the automatic sample feeding mechanism transfers the first test tube to the sample mixing mechanism 2's test tube clamping position. When the sample test tube reaches the sample mixing mechanism 2's test tube clamping position, the sample mixing mechanism 2 clamps the test tube and mixes it. After mixing, the test tube is placed in the transfer chamber 28. The electric linear module 27 drives the transfer chamber 28 to move the test tube to the sampling position. The sampling mechanism 29 receives the sampling command, collects the reagent 1 corresponding to the test mode from the sampling hole 55 of the reagent tray 46, adds it to the reaction cup 58 as the base liquid, then collects the sample from the sampling position and adds it to the reaction cup 58, and mixes it using the sampling needle 37. Finally, the sample is collected from the reagent tray... 46. ​​Reagent 2 corresponding to the test mode is added to reaction cup 58 and mixed well, and the sample reagent mixture begins to react; the multi-source optical detection mechanism 56 receives the detection command, turns on the corresponding light source according to the test mode in the command, and collects the light signal in real time; the sample shaking mechanism 2 puts the sample tube back into the test tube rack, and the sample injection mechanism pushes the next sample tube to the test tube clamping position of the sample shaking mechanism 2, and repeats the above steps. When the test in a certain reaction cup 58 is completed, the light source is turned off, the collected data is transmitted to the instrument control unit (INC) for processing and output of the test results, and the automatic negative pressure liquid circuit system rinses the reaction cup 58.

[0042] This invention discloses a specific protein analyzer that, through a sample mixing mechanism 2, can mix agglomerated or uneven samples without manual processing, thus improving work efficiency and reducing labor costs. When samples are added to reaction cups 58, multiple reaction cups 58 are available, allowing for simultaneous testing of multiple samples or multiple tests on the same sample. The reagent tray 46 can automatically transfer reagents for each test item to the reagent sampling position, enabling automatic selection of multiple reagents. The multi-light source optical detection mechanism 56 has multiple wavelengths of light sources, allowing the use of appropriate light sources according to the test requirements. The angle receiver 62 and angle receiver 63 in the multi-light source optical detection mechanism 56 are respectively a scattering receiver and a transmission receiver, allowing for the simultaneous use of scattering turbidimetry and transmission turbidimetry in the testing methodology. This invention solves the problems of existing specific protein analyzers that can only test one sample at a time, can only test one test per sample simultaneously, and require manual sample mixing and addition.

[0043] The above-disclosed embodiments are merely one or more preferred embodiments of this application and should not be construed as limiting the scope of this application. Those skilled in the art can understand that all or part of the processes for implementing the above embodiments and equivalent changes made in accordance with the claims of this application still fall within the scope of this application.

Claims

1. A specific protein analyzer, comprising an organism, characterized in that, It also includes a sample mixing mechanism; The sample mixing mechanism includes a support frame, a longitudinal linear motion module, a connecting plate, a transmission guide rail, a lifting plate, a rotating shaft, two test tube clamps, a driven lever, a stainless steel bearing, a rotating plate, a mixing rod, a synchronizing rod, a guide block, and a closing module. The support frame is fixedly connected to the inside of the machine body. The longitudinal linear motion module is located on the side of the support frame. The connecting plate is located on the side of the longitudinal linear motion module. The transmission guide rail is fixedly connected to the side of the support frame. The lifting plate is slidably connected to the transmission guide rail and is located on the side of the transmission guide rail. The rotating shaft is rotatably connected to the lifting plate and is located on the side of the lifting plate. The two test tube clamps are sleeved on the side of the rotating shaft. The driven lever is rotatably connected to the rotating shaft and is located at one end of the rotating shaft. The inner ring of the stainless steel bearing is fixedly connected to the driven lever and is located on the side of the driven lever. The rotating plate is fixedly connected to the side of the driven lever. One end of the mixing rod is fixedly connected to the rotating plate, and the other end of the mixing rod passes through one of the test tube clamps. The synchronizing rod is located between the two test tube clamps. The guide block is fixedly connected to the side of the support frame. The guide block has a shaking groove on its side, and the stainless steel bearing is located in the shaking groove. The closing module is located on the two test tube clamps.

2. The specific protein analyzer as described in claim 1, characterized in that, The longitudinal linear motion module includes multiple first synchronous pulleys, a transmission belt, and a lifting motor; the multiple first synchronous pulleys are rotatably connected to the support frame and are located on the side of the support frame respectively; The transmission belt is sleeved on the side of the plurality of first synchronous pulleys; The lifting motor is fixedly connected to the side of the support frame, and the output end of the lifting motor is fixedly connected to the first synchronous pulley.

3. The specific protein analyzer as described in claim 2, characterized in that, The closed module includes two second synchronous pulleys, a synchronous belt, a first clamping plate, a second clamping plate, a first lead screw motor, and a docking plate. The two second synchronous pulleys are rotatably connected to the lifting plate and are located on the sides of the lifting plate. The synchronous belt is sleeved on the sides of the two second synchronous pulleys. One end of the first clamping plate is fixedly connected to the synchronous belt, and the other end is on the rotating shaft. One end of the second clamping plate is fixedly connected to the synchronous belt, and the other end is on the rotating shaft. The first lead screw motor is fixedly connected to the side of the lifting plate. The docking plate is fixedly connected to the lead screw of the first lead screw motor and to the first clamping plate, and is located on the side of the first clamping plate.

4. The specific protein analyzer as described in claim 3, characterized in that, The specific protein analyzer also includes an electric linear module and a transfer chamber; the electric linear module is located inside the main body, and the transfer chamber is located on the side of the electric linear module.

5. The specific protein analyzer as described in claim 4, characterized in that, The specific protein analyzer further includes a sampling mechanism, which comprises a horizontal linear motion module, a vertical guide rail, a second lead screw motor, a slider, a fixed base, a limiting plate, a compression spring, a sampling needle, a positioning optocoupler, a liquid level sensing device, a positioning component, and a mixing device. The horizontal linear motion module is disposed inside the machine body. The vertical guide rail is disposed on the side of the horizontal linear motion module. The second lead screw motor is fixedly connected to the side of the vertical guide rail. The slider is disposed on the second lead screw motor and is slidably connected to the vertical guide rail. The fixed base is fixedly connected to the side of the slider. The limiting plate is fixedly connected to the side of the slider. The compression spring is fixedly connected to the side of the limiting plate. The sampling needle is fixedly connected to the side of the compression spring and passes through the fixed base; the positioning optocoupler is fixedly connected to the side of the vertical guide rail; the liquid level sensing device is fixedly connected to the side of the slider; the positioning component is set at the bottom of the horizontal linear motion module and has a positioning groove; the mixing device is set between the vertical guide rail and the sampling needle.

6. The specific protein analyzer as described in claim 5, characterized in that, The specific protein analyzer also includes a reagent low-temperature storage mechanism, which comprises a base plate, a heat sink, multiple heat dissipation blocks, a reagent tray, a temperature sensor, a pallet, a rotating module, a Peltier, a heat-conducting plate, an air duct, a cooling fan, and an RFID device. The base plate is fixedly connected to the inside of the main body, the heat sink is fixedly connected to the top of the base plate, and the multiple heat dissipation blocks are respectively fixedly connected to one side of the heat sink. The reagent tray is fixedly connected to the top of the heat sink, and the top of the reagent tray has a sampling hole. The temperature sensor is fixedly connected to the side of the reagent tray. The pallet and the reagent tray are rotatably connected and located inside the reagent tray. The rotating module is disposed between the base plate and the pallet. The Peltier is fixedly connected to the top of the heat sink, and the heat-conducting plate is fixedly connected between the Peltier and the reagent tray. The air duct is fixedly connected to the side of the heat sink. The cooling fan is fixedly connected to the side of the air duct. The RFID device is fixedly connected to the side of the reagent tray.

7. The specific protein analyzer as described in claim 6, characterized in that, The specific protein analyzer also includes a multi-source optical detection mechanism, which includes a mounting base, a reaction cup, a first light source, a second light source, a third light source, an angle receiver, and an angle receiver. The mounting base is fixedly connected to the inside of the machine body, the reaction cup is fixedly connected to the inner side of the mounting base, the first light source is fixedly connected to the side of the mounting base, the second light source is fixedly connected to the side of the mounting base, the third light source is fixedly connected to the side of the mounting base, the first angle receiver is fixedly connected to the side of the mounting base, and the second angle receiver is fixedly connected to the side of the mounting base.

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