Blood typing analyzer, blood typing system and blood typing method

Abstract

This invention provides a blood typing analyzer, a blood typing system, and a blood typing method. The blood typing analyzer includes a first operating space and a second operating space. The first operating space is configured as a sample application space and contains a test tube rack, a puncture module, and a second transfer module. The second operating space is configured as a storage and transfer space for microcolumn gel cards, including a card holder for placing the microcolumn gel cards, a centrifugation module, an interpretation module, and a first transfer module. This invention separates the two experimental operations—microcolumn gel card transfer and sample application—which almost cover the entire platform, into two different operating spaces, avoiding mutual interference between the modules responsible for microcolumn gel card transfer and sample application. The blood typing analyzer places each module in its corresponding operating space according to its function. The operation of each module is independent and does not affect the others, eliminating the need for complex movement paths to avoid interference between modules, thus making the blood typing analyzer more efficient.

Description

Technical Field

[0001] This invention relates to the field of blood typing technology, specifically to a blood typing analyzer, a blood typing system, and a blood typing method. Background Technology

[0002] Blood typing analyzers typically include gripper modules (such as card grippers, plate grippers, and tube grippers) and a sample dispensing mechanism. These gripper modules transfer blood cards, well plates, sample tubes, and reagent tubes during blood typing, irregular antibody screening, or crossmatching experiments, while the sample dispensing mechanism aspirates the samples and reagents. Traditional blood typing analyzers have a dispensing area and gripper area on a single platform. The dispensing mechanism and various gripper modules need to move back and forth between these areas. To avoid interference between modules, avoidance paths between modules must be pre-planned, resulting in complex module operation and low efficiency. Summary of the Invention

[0003] The present invention aims to at least solve one of the technical problems existing in the prior art. To this end, the present invention provides a blood typing analyzer that can improve the working efficiency of the blood typing analyzer.

[0004] A blood typing analyzer provided in an embodiment of the present invention includes: The rack has a first operating space and a second operating space inside, with the first operating space located above the second operating space; A card slot is provided in the second operating space. The card slot is used to place a card containing a micropillar gel card. The micropillar gel card has multiple detection holes, and the detection holes are sealed by an encapsulation film. The first transfer module is located in the second operating space and is used to pick up, place and transfer micropillar gel cards within the second operating space. A centrifuge, located in the second operating space, is used to centrifuge the microcolumn gel card; The interpretation module, located in the second operating space, is used to interpret the micropillar gel card; The lifting and transferring module includes a supporting component, which is capable of carrying the micropillar gel card transferred by the first transferring module and lifting and lowering between the first operating space and the second operating space to transfer the micropillar gel card between the first operating space and the second operating space. A puncture module is disposed in the first operating space. The puncture module includes a clamping member and a puncture member. The clamping member is used to clamp the puncture member so that the puncture member punctures the encapsulation film of the micropillar gel card carried on the carrier component. A test tube rack is provided in the first operating space. The test tube rack is used to place sample containers, and the sample containers are used to store liquids. The second transfer module is located in the first operating space and is used to aspirate liquid into the detection well or sample container of the microcolumn gel card.

[0005] The blood typing analyzer according to embodiments of the present invention has at least the following beneficial effects: In this invention, the first operating space is designated as a sample application space, containing a test tube rack, a puncture module, and a second transfer module. The puncture module is used to puncture the microcolumn gel card, and the sample application mechanism moves within the first operating space to apply the sample to the punctured microcolumn gel card. The second operating space is designated as a storage and transfer space for the microcolumn gel card, including a card holder slot, a centrifugation module, an interpretation module, and a first transfer module. The first transfer module transfers the microcolumn gel card within the second operating space. A lifting transfer module transfers the microcolumn gel card between the first and second operating spaces, connecting the two spaces. This invention separates the two experimental operations—microcolumn gel card transfer and sample application—which cover almost the entire platform, into two different operating spaces, avoiding mutual interference between the modules responsible for microcolumn gel card transfer and sample application. The blood typing analyzer places each module within its corresponding operating space according to its function. Each module operates independently and without interference, eliminating the need for complex movement paths to avoid module interference and making the blood typing analyzer more efficient.

[0006] According to some embodiments of the present invention, the puncture module includes a needle box assembly, a first gripping mechanism, and a first moving module. The needle box assembly includes a puncture needle seat for carrying the puncture component. The first gripping mechanism is used to grip the puncture component. The first gripping mechanism is mounted on the first moving module. The first moving module is used to drive the first gripping mechanism to move within the first operating space, so that the first gripping mechanism moves above the needle box assembly to grip the puncture component, or moves above the supporting component, so that the puncture component can puncture the encapsulation film. The lifting and transfer module also includes a lifting drive mechanism, which is connected to the carrier component and can drive the carrier component to rise and fall, so that when the first gripping mechanism moves above the carrier component, it drives the carrier component to rise, so that the puncture member punctures the sealing film.

[0007] According to some embodiments of the present invention, the first operating space includes a plurality of first space units, which are arranged in a horizontal direction. Each first space unit is provided with at least one second transfer module, at least one puncture module and a plurality of test tube racks.

[0008] According to some embodiments of the present invention, the second operating space includes a plurality of second space units, which are arranged in a horizontal direction. Each second space unit is provided with a plurality of card slots and at least one first transfer module. The blood typing analyzer includes a plurality of lifting and lowering transfer modules, which correspond one-to-one with the second space units. The first transfer module in the second space unit transfers microcolumn gel cards between the card slots and the corresponding lifting and lowering transfer modules. And / or, each of the lifting and transferring modules includes multiple load-bearing components, and the lifting and lowering of the multiple load-bearing components are independent of each other.

[0009] According to some embodiments of the present invention, the first operating space includes a plurality of first spatial units arranged horizontally, and each first spatial unit is provided with at least one second transfer module, at least one puncture module and a plurality of test tube racks; the second operating space includes a plurality of second spatial units arranged horizontally, and each second spatial unit is provided with a plurality of card slots and at least one first transfer module, wherein the first transfer module in the second spatial unit transfers microcolumn gel cards between the card slots and the corresponding lifting transfer module, and the first spatial unit and the second spatial unit are vertically aligned; the blood typing analyzer includes a plurality of the lifting transfer modules, and the lifting transfer modules are capable of transferring microcolumn gel cards between the corresponding first spatial unit and the second spatial unit.

[0010] According to some embodiments of the present invention, the second operating space includes a card feeding area and a detection area, the card slot is placed in the card feeding area, the centrifuge and the reading module are disposed in the detection area, the centrifuge and the reading module are arranged along a first direction, and the detection area is disposed on one side of the card feeding area along a second direction; the first direction, the second direction and the vertical direction are perpendicular to each other; The blood typing analyzer also includes a third transfer module, which is located in the second operating space and is capable of transferring microcolumn gel cards within the detection area. The first transfer module is capable of transferring microcolumn gel cards between the lifting transfer module and the centrifuge, and between the interpretation module and the card insertion area.

[0011] According to some embodiments of the present invention, the card insertion area includes a half-card slot for storing a half-card, wherein the half-card is a micropillar gel card with some detection holes already used; the first transfer module is used to transfer the half-card from the interpretation module to the half-card slot.

[0012] According to some embodiments of the present invention, the frame further includes a third operating space located below the second operating space, and the third operating space is provided with at least one material hopper; The judgment module includes a base plate, a judgment unit, a card holder assembly, and an unlocking unit. The card holder assembly is movably disposed above the base plate. The judgment unit is installed above the base plate and faces the card holder assembly. The base plate has a vertically penetrating card discarding slot, which is located directly above the material barrel. The card holder assembly includes an openable clamping unit for clamping the micropillar gel card. The unlocking unit is located on the moving path of the card holder assembly so as to trigger the clamping unit to open when the card holder assembly moves to the card discarding port, so that the micropillar gel card falls into the material bucket through the card discarding port.

[0013] According to some embodiments of the present invention, the rack further includes a third operating space located below the second operating space. The blood typing analyzer also includes a plurality of movable frames arranged along a first direction, the movable frames being movably disposed within the third operating space to enter and exit the third operating space, each of the movable frames carrying at least one material container; the first direction is perpendicular to the vertical direction; wherein, At least one of the material bins is located below the interpretation module, and the material bin is used to store microcolumn gel cards discarded by the interpretation module; And / or, the blood typing analyzer further includes a washing station located in the first operating space, the second transfer module including a sampling needle for aspirating liquid into the detection well of the microcolumn gel card or a sample container, the washing station having a washing tank for inserting the sampling needle, the washing tank being connected to at least one of the material tanks via a pipeline, the material tanks being used to supply cleaning solution to the washing tanks, and the washing station being connected to another material tank via a pipeline and discharging cleaning waste liquid to the material tank.

[0014] According to some embodiments of the present invention, the rack includes a first platform and a second platform arranged vertically at intervals, the first platform being located above the second platform, forming a first operating space above the first platform, the test tube rack being movably connected to the first platform; the second operating space is defined between the first platform and the second platform, and the card slot is supported on the second platform; The first platform includes multiple inlet channels, and the test tube rack is movably connected to the inlet channel along a second direction. The inlet channel has a lifting groove that runs vertically through it. Each inlet channel is provided with a limiting part. Along the second direction, the test tube rack has a spaced transfer position and a sample insertion position. The first transfer module includes a lifting mechanism that can move vertically. The second direction is perpendicular to the vertical direction. When the test tube rack enters the racking channel and moves to the transfer position, the test tube rack abuts against the limiting part. The lifting mechanism lifts the test tube rack through the lifting groove, causing the test tube rack to disengage from the limiting part. After the first transfer module drives the test tube rack to move a preset distance along the second direction, the lifting mechanism descends, placing the test tube rack at the sample feeding position.

[0015] According to some embodiments of the present invention, at least one of the test tube racks is used to carry a dilution strip, the dilution strip being a sample container encapsulated with diluent, the dilution strip including a plurality of dilution holes, each of the dilution holes being encapsulated with diluent, and the second transfer module being able to draw up the sample to be tested from the sample container and inject it into the dilution hole for dilution.

[0016] According to some embodiments of the present invention, the frame is provided with a side plate along the side of a first direction. The side plate includes a transparent panel and a light strip bent into a preset shape. The light strip is fixed to the inside of the panel and can emit light outward through the panel. The first direction is perpendicular to the vertical direction.

[0017] According to a second aspect of the present invention, a blood typing system includes the blood typing analyzer of the first aspect embodiment, wherein the first operating space is provided with a sample introduction area, and the blood typing system further includes: The blood typing analyzer includes a main track and at least one sample inlet track for transporting sample holders. The main track is located outside the blood typing analyzer. One end of the sample inlet track is provided with an inlet and outlet and is connected to the main track. The other end extends into the sample inlet area. The sample holder includes multiple sample positions capable of holding sample containers. The sample holder can move from the inlet and outlet to the sample inlet track via the main track to enter the sample inlet area, and can also move from the inlet and outlet track to the main track at the sample inlet track to exit the sample inlet area. Alternatively, the blood typing system may further include a main track and at least one sample inlet track, the main track and the sample inlet track being used to transport sample holders. The main track is located outside the blood typing analyzer. An inlet and an outlet are provided on the same side of the sample inlet track, both of which are connected to the main track. A portion of the sample inlet track extends into the sample inlet area. The sample holder includes a single sample position capable of holding a sample container. The sample holder can move from the inlet to the sample inlet track via the main track to enter the sample inlet area, and from the sample inlet track to the main track via the outlet to exit the sample inlet area.

[0018] The blood typing method according to a third aspect embodiment of the present invention is executed by the blood typing analyzer in the first aspect embodiment; comprising: The first transfer module is controlled to grasp the micropillar gel card and identify the barcode of the micropillar gel card; The first transfer module transfers the successfully identified microcolumn gel card to the lifting transfer module. At the same time, the puncture module grabs the puncture piece corresponding to the number of puncture holes according to the type of the microcolumn gel card and the test items to be tested in the sample, and moves it above the lifting transfer module. When the lifting and transfer module carries the microcolumn gel card upward to the first operating space, the puncture module punctures the microcolumn gel card. After the second transfer module completes the sample dilution and mixing pretreatment, it transfers the pretreated sample into the corresponding detection well of the microcolumn gel card. The lifting module is controlled to descend to the second operating space carrying the microcolumn gel card; The first transfer module transfers the microcolumn gel card to a centrifuge for centrifugation, and then transfers the centrifuged microcolumn gel card to the interpretation module for interpretation.

[0019] According to some embodiments of the present invention, the blood typing method includes: The first operating space includes multiple first spatial units, and the second operating space includes multiple second spatial units. The first spatial units and the second spatial units correspond one-to-one vertically. The blood type analyzer includes multiple lifting and transferring modules. The lifting and transferring modules correspond one-to-one with the second spatial units and with the first spatial units. The blood type analysis method includes: Obtain the position of the first spatial unit where the test tube rack currently injecting samples is located within the first operating space, and determine the corresponding second spatial unit and lifting and transfer module based on the position; The first transfer module is controlled to grab the microcolumn gel card in the corresponding second spatial unit and transfer it to the corresponding lifting transfer module; at the same time, according to the position of the current sample injection tube rack in the first spatial unit, the puncture module in the same first spatial unit is controlled to grab the puncture piece and move it above the corresponding lifting transfer module. The puncture module is controlled to complete the puncture of the microcolumn gel card when the lifting and transfer module carries the microcolumn gel card to the first operating space; Based on the position of the test tube rack currently being injected in the first spatial unit, the second transfer module within the same first spatial unit is controlled to transfer the pretreated sample to the detection well of the microcolumn gel card; The lifting and transfer module is controlled to descend to the second operating space, carrying the microcolumn gel card.

[0020] According to some embodiments of the present invention, the blood typing method includes: the blood typing analyzer further includes a quality detection module, the quality detection module being disposed in the second operating space, and the blood typing method includes: Before the first transfer module transfers the microcolumn gel card to the lifting transfer module, the microcolumn gel card undergoes quality testing. If the microcolumn gel card passes the test, the first transfer module will transfer the microcolumn gel card to the lifting and lowering transfer module. If the microcolumn gel card fails the test, the first transfer module will transfer the microcolumn gel card to the original card box and mark it.

[0021] According to some embodiments of the present invention, the blood typing analyzer further includes a third operating space located below the second operating space, the second operating space having a semi-locking position, and the blood typing analysis method further includes: After the judgment module completes the judgment, if there is no doubt about the judgment result and there are unused detection holes in the current micropillar gel card, the first transfer module is controlled to transfer the micropillar gel card to the half card position. If there is no doubt about the interpretation result, and all the detection wells in the current micropillar gel card have been used, the interpretation module will discard the interpreted micropillar gel card into the material bucket in the third operating space. If there is any doubt about the interpretation result, the first transfer module is controlled to transfer the interpreted micropillar gel card to the original card box and mark it.

[0022] According to some embodiments of the present invention, an abnormal card slot is provided in the second operating space, and the blood type analysis method includes: When the blood typing analyzer stops or loses power during the transfer of the microcolumn gel card by the first transfer module, the first transfer module is controlled to maintain the clamping state of the microcolumn gel card. After the blood typing analyzer resumes operation, if the first transfer module holds the microcolumn gel card, it controls the first transfer module to continue the transfer operation of the microcolumn gel card according to the current detection progress of the microcolumn gel card, or to transfer the microcolumn gel card to the abnormal card position. And / or, the blood typing analyzer further includes a third transfer module and a third operating space, the third transfer module being disposed in the second operating space and capable of transferring microcolumn gel cards within the detection area, the second operating space having an abnormal card position, and the third operating space having a material container; the blood typing analysis method includes: When the blood typing analyzer stops or loses power during the transfer of the microcolumn gel card by the third transfer module, the third transfer module maintains the clamping state of the microcolumn gel card. After the blood typing analyzer resumes operation, if the third transfer module holds the microcolumn gel card, it controls the third transfer module to continue performing the transfer operation on the microcolumn gel card according to the current detection progress of the microcolumn gel card. Alternatively, the third transfer module can be controlled to place the microcolumn gel card into the interpretation module, and the interpretation module can then drop the microcolumn gel card into the material bucket of the third operating space. Alternatively, the third transfer module and / or the first transfer module can be controlled to transfer the micropillar gel card to the abnormal card position.

[0023] Other features and advantages of the invention will be set forth in the description which follows, and will be apparent in part from the description, or may be learned by practicing the invention. Attached Figure Description

[0024] The present invention will be further described below with reference to the accompanying drawings and embodiments, wherein: Figure 1 This is a schematic diagram of one embodiment of the blood typing analyzer of the present invention; Figure 2 A schematic diagram of the blood typing analyzer of the present invention from another perspective; Figure 3 This is a schematic diagram of one embodiment of the modules within the second operating space; Figure 4 A schematic diagram of one embodiment of the micropillar gel card; Figure 5 This is a schematic diagram of one embodiment of the modules within the first operating space; Figure 6 This is a schematic diagram of one embodiment of the second transfer module; Figure 7 This is a schematic diagram showing the coordination between the modules in the first and second operating spaces; Figure 8 A schematic diagram illustrating the cooperation between the lifting and transfer module and the puncture module in one embodiment; Figure 9 This is a schematic diagram illustrating the cooperation between a first mobile module and a first grasping mechanism in one embodiment. Figure 10 A schematic diagram of one embodiment of the pin header assembly; Figure 11 A top view of one embodiment of the first platform; Figure 12 A top view of one embodiment of the second platform; Figure 13 This is a schematic diagram of one embodiment of a centrifuge; Figure 14 This is a schematic diagram of one embodiment of the first transfer module; Figure 15 This is a schematic diagram of the modules in the third operating space; Figure 16 This is a schematic diagram of one embodiment of the interpretation module; Figure 17 for Figure 7 Enlarged view of point A in the middle; Figure 18 This is a schematic diagram illustrating the cooperation between the first transfer module and the rack entry channel in one embodiment. Figure 19 This is a schematic diagram of the cooperation between the test tube rack and the first transfer module during the process of the test tube rack being placed into the rack. (a) The test tube rack is moved to the transfer position. Figure 20 (a) is a schematic diagram of the cooperation between the test tube rack and the first transfer module during the loading process. (b) shows the test tube rack moving to the sample loading position. Figure 21 A schematic diagram of one embodiment of the dilution bar; Figure 22 An exploded view of one embodiment of the side panel; Figure 23 This is a schematic diagram of one embodiment of a sample analysis system; Figure 24 This is a schematic diagram of another embodiment of the sample analysis system.

[0025] Icon labels: Frame 10, First operating space 101, Second operating space 102, First platform 103, Second platform 104, Sample loading area 105, First spatial unit 1051, Left first spatial unit 1051a, Right first spatial unit 1051b, Card loading area 106, Second spatial unit 1061, Left second spatial unit 1061a, Right second spatial unit 1061b, Half card slot 1063, Abnormal card slot 1064, New card drawer 107, Detection area 108, Third operating space 109, Third platform 110, Card slot 11, First transfer module 12, Barcode scanning unit 121, Second gripper Components include: 122 (grabbing mechanism), 123 (fiber optic head), 124 (photoelectric detection unit), 125 (lifting mechanism), 1251 (lifting component), 13 (microcolumn gel card), 131 (detection hole), 14 (test tube rack), 141 (magnet), 142 (detection baffle), 143 (base), 149 (dilution seal), 15 (puncture module), 15 (first puncture module), 15b (second puncture module), 151 (first grasping mechanism), 152 (puncture component), 153 (needle box assembly), 1531 (puncture needle holder), 154 (first moving module), 16 (sample dispensing mechanism), 16a (first sample dispensing mechanism), 16b (second sample dispensing mechanism), 161 (sample dispensing needle), 17 (second transfer module), and 18 (left). Second transfer module 17a, right second transfer module 17b, encoder 171, first transmission unit 172, second transmission unit 173, synchronous belt 1731, driving wheel 1732, driven wheel 1733, lifting transfer module 18, first lifting transfer module 18a, second lifting transfer module 18b, bearing component 181, lifting drive mechanism 182, centrifuge 19, cabin 191, top cover 192, cover 194, cover opening drive component 195, interpretation module 20, base plate 201, discard bayonet 2011, interpretation unit 202, bayonet assembly 203, clamping unit 205, third transfer module 17a, right second transfer module 17b, encoder 171, first transmission unit 172, second transmission unit 173, synchronous belt 1731, driving wheel 1732, driven wheel 1733, driven transfer module 18, first lifting transfer module 18a, second lifting transfer module 18b, bearing component 181, lifting drive mechanism 182, centrifuge 19, cabin 191, top cover 192, cover 194, cover opening drive component 195, interpretation module 20, base plate 201, discard bayonet slot 2011, interpretation unit 202, bayonet seat assembly 203, clamping unit 205, third transfer module 17a, right second transfer module 17b, encoder 171, first transmission unit 172, second transmission unit 173, synchronous belt 1731, driving wheel 1732, driven wheel 1733, driven wheel 1733, driven wheel 1733, driven wheel 1733, driven wheel 1733, driven wheel 1743, driven wheel 175, driven wheel 1733, driven wheel 1743, driven wheel 175, driven wheel 1 Module 21, Incubation Module 22, Quality Inspection Module 23, Movable Frame 24, Material Bucket 25, Washing Station 26, Forced Exhaust Pump 27, Pump Valve Box 28, Connecting Container 29, Power Control Box 30, Control Module 31, Frame Entry Channel 32, Guide Bar 321, Lifting Slot 322, Limiting Part 323, Frame Entry Sensor 324, Position Detection Sensor 325, Connector Assembly 33, Side Plate 34, Panel 341, Light Strip 342, Inner Plate 343, Main Track 35, Sample Inlet Track 36, Inlet / Outlet 361, Inlet 362, Outlet 363, Sample Inlet Section 364, Sample Outlet Section 365, Turntable 37, Diverter 38. Detailed Implementation

[0026] Embodiments of the present invention are described in detail below. Examples of these embodiments are shown in the accompanying drawings, wherein the same or similar reference numerals denote the same or similar elements or elements having the same or similar functions throughout. The embodiments described below with reference to the accompanying drawings are exemplary and are only used to explain the present invention, and should not be construed as limiting the present invention.

[0027] In the description of this invention, it should be understood that the orientation descriptions, such as up, down, etc., are based on the orientation or positional relationship shown in the drawings and are only for the convenience of describing this invention and simplifying the description, and are not intended to indicate or imply that the device or element referred to must have a specific orientation, or be constructed and operated in a specific orientation, and therefore should not be construed as a limitation of this invention.

[0028] In the description of this invention, "multiple" refers to two or more. The use of "first" and "second" is for distinguishing technical features only and should not be construed as indicating or implying relative importance, or implicitly indicating the number of indicated technical features or their sequential relationship.

[0029] In the description of this invention, unless otherwise explicitly defined, terms such as "set up," "install," and "connect" should be interpreted broadly, and those skilled in the art can reasonably determine the specific meaning of the above terms in this invention in conjunction with the specific content of the technical solution.

[0030] The technical solution of the present invention will be clearly and completely described below with reference to the accompanying drawings. Obviously, the embodiments described below are some embodiments of the present invention, not all embodiments.

[0031] To address the issues of cumbersome path planning in traditional blood typing analyzers, which leads to complex operation and low efficiency, this invention provides a blood typing analyzer. (Refer to...) Figure 1 and Figure 2 The blood typing analyzer includes a frame 10, which has multiple operating spaces inside, allowing different operating modules to move independently within their respective spaces. Specifically, the frame 10 divides the internal space of the instrument into a first operating space 101 and a second operating space 102, with the first operating space 101 located above the second operating space 102. In some embodiments, the frame 10 includes a first platform 103 and a second platform 104, with the first platform 103 mounted above the second platform 104. The first operating space 101 is defined above the first platform 103 and the top of the frame, and the second operating space 102 is defined between the first platform 103 and the second platform 104.

[0032] Reference Figures 1 to 3 The blood typing analyzer also includes a cartridge slot 11, a first transfer module 12, a centrifuge 19, and a reading module 20. The cartridge slot 11, centrifuge 19, and reading module 20 are all located within the second operating space 102. Multiple cartridge slots 11 can be provided, arranged in multiple rows and columns. Combined with... Figure 4The cartridge slot 11 is used to place the microcolumn gel card 13. The microcolumn gel card 13 can be placed in the cartridge first. The cartridge can have single or multiple rows of slots. The microcolumn gel card 13 is placed in the slot, and the cartridge is placed in the cartridge slot 11. The microcolumn gel method uses the microcolumn gel card 13 as a detection carrier. The microcolumn gel card 13 includes multiple detection wells 131. The microcolumns in the detection wells 131 contain a gel mixture for detection. Based on the detection requirements, antibodies and / or buffer solutions are pre-filled.

[0033] The first transfer module 12 is used to transfer the micropillar gel card 13 within the second operating space 102. For example, the first transfer module 12 can remove the micropillar gel card 13 from the card slot 11 and transfer the micropillar gel card 13 to other modules in the second operating space 102, or transfer the micropillar gel card 13 from other modules in the second operating space 102 to the card slot 11. Other modules include a lifting and transferring module 18, a centrifuge 19, a reading module 20, a half-card position 1063, and an abnormal card position 1064, etc.

[0034] Centrifuge 19 is used to centrifuge the microcolumn gel card 13 after sample loading. After centrifugation, obvious stratification occurs within the gel microcolumn (detection well 131). Interpretation module 20 interprets the centrifuged microcolumn gel card 13. In some embodiments, such as... Figure 16 As shown, the interpretation module 20 includes an interpretation unit 202, which can capture images of each gel microcolumn in the microcolumn gel card 13 so that the system can identify the red blood cell agglutination in each gel microcolumn and determine the test results of experiments such as blood type, irregular antibody screening or crossmatching of the sample to be tested.

[0035] Reference Figure 5 and Figure 6 The blood typing analyzer also includes a test tube rack 14, a puncture module 15, and a second transfer module 17. The test tube rack 14, puncture module 15, and second transfer module 17 are all located in the first operating space 101. The test tube rack 14 is placed on the first platform 103 and is used to hold sample containers containing samples (such as blood), reaction reagents, diluents, etc. The sample containers are not limited to test tubes, reagent bottles, reaction cups, etc. In some embodiments, the first platform 103 is provided with a structure that slides with the test tube rack 14, allowing the test tube rack 14 to easily enter and exit the first operating space 101; the test tube rack 14 can accommodate multiple sample containers, for example, the test tube rack 14 has one or more rows of placement positions, and the sample containers are arranged in a single row or multiple rows after being placed in the placement positions; the puncture module 15 includes a clamping member for clamping the puncture member 152, which is used to puncture the encapsulation film on the micropillar gel card 13, so that the second transfer module 17 can inject liquid substances, such as the sample to be tested, reaction reagents, or a mixture of sample and diluent, into the detection hole 131 of the micropillar gel card 13.

[0036] The second transfer module 17 is used to aspirate liquid into the detection hole 131 (gel micropillar) or sample container of the micropillar gel card 13 within the first operating space 101. In some embodiments, the second transfer module 17 includes a sample application mechanism 16 and a second moving module. The sample application mechanism 16 is mounted on the second moving module, and the second moving module drives the sample application mechanism 16 to move within the first operating space 101. The sample application mechanism 16 includes a sample application needle 161, which can be inserted into the detection hole 131 or sample container of the micropillar gel card 13, so that the sample application mechanism 16 can aspirate liquid into the detection hole 131 or sample container.

[0037] In this embodiment, refer to Figure 3 and Figure 7 The blood typing analyzer also includes a lifting and transfer module 18, which includes a support component 181. The support component 181 can support the microcolumn gel card 13. The support component 181 can be provided with multiple slots for placing the microcolumn gel card 13, so that the microcolumn gel card 13 is stably placed on the support component 181. The support component 181 can be lifted and lowered between the first operating space 101 and the second operating space 102 to realize the transfer of the microcolumn gel card 13 between the first operating space 101 and the second operating space 102. For example, a new microcolumn gel card 13 is transferred from the first transfer module 12 to the carrier component 181. The carrier component 181 rises, transferring the microcolumn gel card 13 from the second operating space 102 to the first operating space 101. The puncture component 152 punctures the encapsulation film of the microcolumn gel card 13 carried on the carrier component 181. Then, the sample addition mechanism 16 can add a sample into the detection hole 131 of the microcolumn gel card 13. After the sample addition is completed, the microcolumn gel card 13 follows the carrier component 181 down and returns to the second operating space 102 for further incubation, centrifugation, interpretation and other processing of the microcolumn gel card 13.

[0038] In this invention, the first operating space 101 is configured as a sample loading space, and is equipped with a test tube rack 14, a puncture module 15, and a second transfer module 17. The puncture module 15 is used to puncture the microcolumn gel card 13. The sample loading mechanism 16 (e.g., a sample loading arm) moves within the first operating space 101 to load the punctured microcolumn gel card 13. The second operating space 102 is configured as a transfer space for the microcolumn gel card 13, including a card slot 11 for placing the microcolumn gel card 13, a centrifugation module 19, an interpretation module 20, and a first transfer module 12 (e.g., a card gripper arm). The first transfer module 12 transfers the microcolumn gel card 13 within the second operating space 102. The lifting and lowering transfer module 18 transfers the microcolumn gel card 13 between the first operating space 101 and the second operating space 102, connecting the two operating spaces. This invention separates the two experimental operations of transferring and dispensing the microcolumn gel card 13—which cover almost the entire platform—into two different operating spaces. This avoids mutual interference between the modules responsible for transferring and dispensing the microcolumn gel card 13 (e.g., the card gripper arm and the sample dispensing arm). The blood typing analyzer places each module within its corresponding operating space according to its function, ensuring independent operation without mutual interference. This eliminates the need for complex movement paths to avoid module interference, making the blood typing analyzer more efficient.

[0039] Reference Figure 8 The lifting and transfer module 18 also includes a lifting drive mechanism 182. The supporting component 181 is connected to the lifting drive mechanism 182, and the lifting drive mechanism 182 is used to drive the supporting component 181 to lift. The lifting drive mechanism 182 is not limited to being a lead screw mechanism, a gear and rack drive mechanism, a synchronous belt 1731 transmission mechanism, etc. In one embodiment, a lifting and transfer module 18 includes two supporting components 181 and two independently lifting drive mechanisms 182, each lifting drive mechanism 182 controlling the lifting of one supporting component 181. In this way, the two supporting components 181 can work independently, and the puncture and sample addition operations in the first operating space 101 can be performed synchronously with the transfer operation of the microcolumn gel card 13 in the second operating space 102, thereby shortening the waiting time in the blood typing analysis process and improving the working efficiency of the blood typing analyzer.

[0040] Reference Figures 8 to 10The puncture module 15 includes a first gripping mechanism 151, which grips the puncture component 152. The puncture component 152 includes a puncture body and a puncture needle. The puncture needle is located at the end of the puncture body and is used to puncture the encapsulation film of the micropillar gel card 13. The first gripping mechanism 151 can grip the puncture body. Based on different blood type analysis requirements, the puncture component 152 needs to puncture the detection holes 131 at different positions on the micropillar gel card 13, or puncture different numbers of detection holes 131 on the micropillar gel card 13. Therefore, the puncture device 152 may include one or more puncture needles. The first gripping mechanism 151 grips the puncture device 152 with a corresponding number of puncture needles according to the current detection requirements to perform a puncture operation on the micropillar gel card 13. For example, if it is necessary to puncture the encapsulation film of the four detection holes 131 in the micropillar gel card 13, the puncture device 152 gripped by the first gripping mechanism 151 has four puncture needles, or the puncture device 152 gripped by the first gripping mechanism 151 has two puncture needles and performs two puncture operations.

[0041] The puncture module 15 also includes a needle box assembly 153, which includes a puncture needle holder 1531. The puncture needle holder 1531 is used to carry the puncture piece 152. Based on the different carrying requirements of different types of puncture pieces 152, such as different puncture pieces 152 having different numbers of puncture needles or different spacing between puncture needles, the puncture needle holder 1531 is provided with different carrying positions to carry the corresponding puncture pieces 152, so that the carrying positions correspond one-to-one with the puncture pieces 152, realizing the foolproof placement of the puncture pieces 152, avoiding the puncture pieces 152 being placed incorrectly by human error, and the first gripping mechanism 151 gripping incorrectly. The puncture module 15 also includes a first moving module 154, and a first gripping mechanism 151 is mounted on the first moving module 154. The first moving module 154 is used to drive the first gripping mechanism 151 to move within the first operating space 101, so that the first gripping mechanism 151 moves above the needle box assembly 153 to grip the puncture member 152, or moves above the support member 181 so that the puncture member 152 can puncture the encapsulation film.

[0042] When the puncture component 152 performs the puncture action, the puncture component 152 is located directly above the support component 181. In one embodiment, the support component 181 is set to remain stationary during the puncture process, so that the position of the micropillar gel card 13 is fixed. The first moving module 154 drives the first gripping mechanism 151 to carry the puncture component 152 down, so that the puncture component 152 moves downward, allowing the puncture needle to puncture the encapsulation film of the micropillar gel card 13 and complete the puncture operation.

[0043] In another embodiment, the first moving module 154 drives the first gripping mechanism 151 to move the puncture component 152 to directly above the bearing component 181 and then stops. The position of the puncture needle is fixed. The lifting drive mechanism 182 drives the bearing component 181 to rise, so that the micropillar gel card 13 moves upward, allowing the puncture needle to puncture the encapsulation film and complete the puncture operation.

[0044] The micropillar gel card 13 completes the puncture while being transferred to the first operating space 101 along with the carrier component 181, resulting in a compact process cycle and improved puncture efficiency. Simultaneously, the micropillar gel card is moved in the Z-direction by the lifting and transfer module 18's built-in lifting drive mechanism 182 to complete the puncture action. This eliminates the need to set up a Z-direction drive for the puncture module, allowing the lifting drive mechanism 182 to reuse its function and simplify the product structure.

[0045] Reference Figure 5 Multiple test tube racks 14 can be provided, and these racks are arranged along a first direction within the first operating space 101. Different test tube racks 14 can be used to place containers containing different liquid substances. For ease of description, a test tube rack 14 containing a sample to be tested is defined as a sample strip, a test tube rack 14 containing a diluent is defined as a dilution strip, and a test tube rack 14 containing a reaction reagent is defined as a reagent strip. Furthermore, a reagent strip can be equipped with a mixer; such a reagent strip is called a mixing strip. The mixing strip is used to mix samples containing diluent and / or diluted samples. It should be noted that one or more sample strips can be pre-set as emergency strips. The container of the emergency strip stores emergency samples. After the emergency strip is injected, the blood typing analyzer prioritizes processing the emergency samples, enabling the blood typing analyzer to have emergency function.

[0046] The test tube rack 14 can enter and exit the first operating space 101 along the second direction and is arranged in the first operating space 101 along the first direction. In one embodiment, the second direction is set as the front-back direction of the blood type analyzer and the first direction is set as the left-right direction of the blood type analyzer. When the operator pushes the test tube rack 14 into the first operating space 101 or takes out the test tube rack 14, the front side of the blood type analyzer faces the operator to facilitate the entry and exit of the test tube rack 14.

[0047] Similarly, refer to Figure 3 and Figure 12 In one embodiment, the blood typing analyzer includes at least one new card drawer 107, with a card holder slot 11 placed inside the new card drawer 107. If multiple new card drawers 107 are provided, the multiple new card drawers 107 are arranged along a first direction. The new card drawers 107 are movably connected to a second platform 104 along a second direction. The operator can push or pull the new card drawer 107 along the second direction to insert or remove the microcolumn gel card 13 into the card holder slot 11.

[0048] Reference Figure 11 In one embodiment, the first operating space 101 includes a plurality of first spatial units 1051 arranged horizontally. Each first spatial unit 1051 is provided with at least one second transfer module 17, at least one puncture module 15, and a plurality of test tube racks 14. It should be noted that the plurality of first spatial units 1051 may be arranged along a first direction, or along a second direction, or simultaneously along both directions. For example, the first operating space 101 may include two first spatial units 1051, which are distributed front to back within the first operating space 101; or, the two first spatial units 1051 may be distributed left to right within the first operating space 101; or, the first operating space 101 may include three first spatial units 1051, with one distributed at the front and the other two at the rear, the two rear units being distributed left to right.

[0049] In one embodiment, the lifting and transfer module 18 is located on the side of the first platform 103 and the second platform 104 along a first direction or a second direction. For example, the lifting and transfer module 18 is located on the left, right, or rear side of the first platform 103 and the second platform 104. At least one side of the first spatial unit 1051 is adjacent to the edge of the first operating space 101, so that each spatial unit 1051 can be maximized to be close to the corresponding lifting and transfer module 18, which facilitates the lifting and transfer module 18 to pick up and put the micropillar gel card 13 into the first spatial unit 1051. For example, there are two lifting and transfer modules 18. Located on the left and right sides of the first platform 103 and the second platform 104 respectively, the first operating space 101 includes two first spatial units 1051 arranged along the first direction. The left side of the first spatial unit 1051 located on the left is adjacent to the left edge of the first operating space 101. The lifting and transfer module 18 on the left transports the micropillar gel card 13 to the first spatial unit 1051 located on the left. Similarly, the right side of the first spatial unit 1051 located on the right is adjacent to the right edge of the first operating space 1051. The lifting and transfer module 18 on the right transports the micropillar gel card 13 to the first spatial unit 1051 located on the right.

[0050] Understandably, the second transfer module 17 only aspirates liquid into the sample container and microcolumn gel card 13 within its respective first spatial unit 1051, and the puncture module 15 only punctures the microcolumn gel card 13 within its respective first spatial unit 1051. Furthermore, each first spatial unit 1051 integrates the aspiration function of the second transfer module 17 into the sample container and microcolumn gel card 13 and the puncture function of the puncture module 15. On the one hand, the first transfer module 17 and the puncture module 15 do not need to cross different spatial units to perform aspiration or puncture actions. Their movement paths are short, and the response efficiency of aspiration and puncture actions is high. Moreover, the first transfer module 17 and the puncture module 15 in different first spatial units 1051 can perform aspiration or puncture actions simultaneously, thereby improving the sample processing capacity and working efficiency of the blood typing analyzer per unit time.

[0051] Taking a first operating space 101 with two first spatial units 1051 arranged along a first direction as an example, the two first spatial units 1051 are a left first spatial unit 1051a and a right first spatial unit 1051b, as follows: Figure 1 , Figure 2 , Figure 5 and Figure 11 As shown, the first operating space 101 includes a left first space unit 1051a and a right first space unit 1051b arranged along a first direction. Both the left first space unit 1051a and the right first space unit 1051b are equipped with multiple test tube racks 14 arranged along the first direction. The first direction is perpendicular to the vertical direction. The blood typing analyzer includes two sets of sample dispensing mechanisms 16, two puncture modules 15, two second transfer modules 17, and two lifting transfer modules 18. The two sets of sample dispensing mechanisms 16, two puncture modules 15, two second transfer modules 17, and two lifting transfer modules 18 are respectively located on both sides of the sample injection area 105 along the first direction. That is, the sample injection area 105 is located along the first direction. Each side is provided with a puncture module 15, a second transfer module 17, and a lifting transfer module 18. The sample feeding mechanism 16, puncture module 15, second transfer module 17, and lifting transfer module 18 near the left first spatial unit 1051a are defined as the first sample feeding mechanism 16a, the first puncture module 15a, the left second transfer module 17a, and the first lifting transfer module 18a, respectively. The sample feeding mechanism 16, puncture module 15, second transfer module 17, and lifting transfer module 18 near the right first spatial unit 1051b are defined as the second sample feeding mechanism 16b, the second puncture module 15b, the right second transfer module 17b, and the second lifting transfer module 18b, respectively.

[0052] Thus, the modules located within the first operating space 101 are symmetrically arranged along the first direction, forming a left operating area and a right operating area. The first sample application mechanism 16a, the first puncture module 15a, the left second transfer module 17a, and the first lifting transfer module 18a move within the left operating area, while the second sample application mechanism 16b, the second puncture module 15b, the right second transfer module 17b, and the second lifting transfer module 18b move within the right operating area. The first lifting transfer module 18a and the second lifting transfer module 18b only transport the microcolumn gel card 13 in the vertical direction and will not interfere with other modules within the first operating space 101. Thus, the arrangement of two sets of functionally identical and symmetrical modules within the first operating space 101 can improve the detection efficiency of the blood typing instrument, and each module moves independently within its own left and right operating areas without affecting the others.

[0053] Furthermore, the sample dispensing mechanism 16 includes two sample dispensing mechanisms 16. Both the left second transfer module 17 and the right second transfer module 17 are equipped with two sample dispensing mechanisms 16. Two sample dispensing mechanisms 16 are present in both the left and right operating areas to aspirate samples, which can further improve sample dispensing efficiency. In one embodiment, the two sample dispensing mechanisms 16 can move along a second direction. Both the left second transfer module 17 and the right second transfer module 17 can drive the two sample dispensing mechanisms 16 to move along a first direction. The two sample dispensing mechanisms 16 can be driven to move along the second direction within either the left or right operating area, which can reduce the probability of interference between the sample dispensing mechanisms 16 in the left and right operating areas.

[0054] In one embodiment, the second operating space 102 includes a plurality of second spatial units 1061 arranged horizontally. Each second spatial unit 1061 is provided with a plurality of card slots 11 and at least one first transfer module 12. The blood typing analyzer includes a plurality of lifting transfer modules 18, which correspond one-to-one with the second spatial units 1061. The first transfer module 12 in the second spatial unit 1061 transfers the microcolumn gel card 13 between the card slot 11 and the corresponding lifting transfer module 18. It should be noted that the plurality of second spatial units 1061 can be arranged along a first direction, or the plurality of second spatial units 1061 can be arranged along a second direction, or the plurality of second spatial units 1061 can be arranged simultaneously along both the first and second directions; for example, the plurality of second spatial units 1052 are respectively disposed on the front and rear sides of the second operating space 102, or the plurality of second spatial units 1052 are respectively disposed on the front, left and right sides of the second operating space 102.

[0055] It is understood that the first transfer module 12 only transfers the microcolumn gel card 13 within its respective second space unit 1061, so as to transfer the microcolumn gel card 13 between the card slot 11 and the corresponding lifting transfer module 18; the first transfer module 12 in different second space units 1061 can simultaneously perform the transfer operation of the microcolumn gel card 13, thereby improving the transfer volume and working efficiency of the blood typing analyzer per unit time.

[0056] Taking the second operating space 102 as an example, which has two second spatial units 1061 arranged along the first direction, the two second spatial units 1061 are the left second spatial unit 1061a and the right second spatial unit 1061b, respectively. Figure 12 The second operating space 102 includes a left second space unit 1061a and a right second space unit 1061b arranged along the first direction. Both the left second space unit 1061a and the right second space unit 1061b are provided with multiple card slots 11. Figure 3 In the illustrated embodiment, the blood typing analyzer includes two new card drawers 107, which are respectively located in the left second space unit 1061a and the right second space unit 1061b. Each new card drawer 107 has multiple card slots 11. Operators can push and pull the new card drawers 107 to retrieve or place micropillar gel cards 13 into the left second space unit 1061a or the right second space unit 1061b.

[0057] In the case where the first operating space 101 includes multiple first spatial units 1051 and the second operating space 102 includes multiple second spatial units 1061, the lifting and transfer module 18 can transport the micropillar gel card 13 between the corresponding first spatial unit 1051 and second spatial unit 1061 in the vertical direction.

[0058] Since the first spatial unit 1051 and the second spatial unit 1061 are vertically aligned, after the first transfer module 12 transfers the micropillar gel card 13 in the card slot 11 to the corresponding lifting transfer module 18, the lifting transfer module 18 directly transports the micropillar gel card 13 upwards, so that the micropillar gel card 13 can be transferred to the corresponding first spatial unit 1051, where the puncture module 15 in the first spatial unit 1051 can puncture the micropillar gel card 13, and the second transfer module 17 can aspirate liquid into the micropillar gel card 13. The transfer efficiency of the micropillar gel card 13 between the first spatial unit 1051 and the second spatial unit 1061 is high.

[0059] Taking a first operating space 101 with two first space units 1051 along a first direction (defined as the left and right direction) and a second operating space 102 with two second operating spaces 1061 along the first direction as an example, the blood typing analyzer includes two lifting and transferring modules 18. The two lifting and transferring modules 18 are respectively located on both sides of the second operating space 102 along the first direction. The lifting and transferring module 18 closer to the left second space unit 1061a is defined as the first lifting and transferring module 18a, and the lifting and transferring module 18 closer to the right second space unit 1061b is defined as the second lifting and transferring module 18b.

[0060] Thus, the modules located within the second operating space 102 are symmetrically arranged along the first direction, forming a left operating area and a right operating area. The first lifting and transferring module 18a moves within the left half of the second operating space 102, and the second lifting and transferring module 18b moves within the right half of the second operating space 102. The first lifting and transferring module 18a and the second lifting and transferring module 18b only transport the microcolumn gel card 13 in the vertical direction and will not interfere with other modules within the second operating space 102. The first transfer modules 12 within the left and right operating areas can transfer the microcolumn gel card 13 between the left second space unit 1061a and the first lifting and transferring module 18a within their respective areas. There is no interference between the first transfer modules 12 in the two areas, which simplifies the movement path of the first transfer modules 12 and improves the working efficiency of the blood typing analyzer.

[0061] Understandably, the activation order of the modules in the first and second spatial units is related to the sample insertion position of the test tube rack 14. The system detects which test tube rack 14 in the first spatial unit is being inserted, and prioritizes the activation of the second transfer module in that first spatial unit, and also prioritizes the activation of the first transfer module in the vertically corresponding second spatial unit. For example, if the test tube rack 14 is inserted in the left operating area of ​​the first operating space 101, the blood typing analyzer selects the left operating area as the priority processing area. The first transfer module 12 prioritizes transferring the microcolumn gel card 13 within the left half of the second operating space 102 to the first lifting transfer module 18. The left second transfer module 17 aspirates liquid into the sample container in the left operating area or the microcolumn gel card 13 transferred by the first lifting transfer module 18. This shortens the movement path of the first transfer module 12 and the second transfer module 17, improving the working efficiency of the blood typing analyzer.

[0062] In one embodiment, reference is made to Figure 3 and Figure 12 The second operating space 102 includes a card insertion area 106 and a detection area 108. A card slot 11 is located within the card insertion area 106, and the detection area 108 is located on one side of the card insertion area 106 along the second direction. For example, the detection area 108 may be located on the rear side of the card insertion area 106. Figure 3 and Figure 12 Centrifuge 19 and interpretation module 20 are both located in detection area 108, and centrifuge 19 and interpretation module 20 are arranged along the first direction.

[0063] The blood typing analyzer also includes a third transfer module 21, which is located within the second operating space 102 and can transfer the microcolumn gel card 13 within the detection area 108. For example, after centrifugation, the microcolumn gel card 13 can be removed from the centrifuge 19 and placed into the interpretation module 20 for interpretation. The travel of the first transfer module 12 can cover all functional modules within the second operating space 102, facilitating the transfer of the microcolumn gel card 13. A dedicated transfer module (third transfer module 21) is provided for the centrifugation and interpretation module 20, allowing the first transfer module 12 to process the next batch of samples while the previous batch is being interpreted, thus improving detection efficiency. For example, after the lifting and transfer module 18 transports the microcolumn gel card 13 with the sample added to the second operating space 102, the first transfer module 12 transfers the microcolumn gel card 13 on the lifting and transfer module 18 to the centrifuge 19 for centrifugation. After centrifugation, the third transfer module 21 sequentially grabs the centrifuged microcolumn gel card 13 and transfers it to the interpretation module 20 for interpretation. The first transfer module 12 transfers the microcolumn gel card 12 between the card slot 11 and the lifting and transfer module 18, thereby improving work efficiency.

[0064] In this embodiment, the detection area 108 and the card insertion area 106 are arranged along the front-to-back direction. The third transfer module 21 only transfers the micropillar gel card 13 within the detection area 108, without affecting the first transfer module 12's transfer of the micropillar gel card 13 between the detection area 108 and the lifting transfer module 18, or between the detection area 108 and the card insertion area 106. The first transfer module 12 and the third transfer module 21 transfer the micropillar gel card 13 within the card insertion area 106 and the detection area 108, respectively. The micropillar gel card 13 can be scheduled within the second operating space 102 through different transfer modules, resulting in high transfer efficiency for the micropillar gel card 13.

[0065] The blood typing analyzer may include multiple centrifuges 19 arranged along a first direction. Different centrifuges 19 can perform centrifugation operations simultaneously, increasing the centrifugation capacity of the blood typing analyzer and improving its working efficiency. In the case where the blood typing analyzer includes multiple centrifuges 19, the interpretation module 20 can be positioned between two centrifuges 19, so that the interpretation module 20 is as close as possible to the center of the detection area 108 in the first direction. This shortens the travel distance of the third transfer module 21 when transferring the microcolumn gel card 13 from the centrifuge 19 to the interpretation module 20, thereby improving the transfer efficiency of the microcolumn gel card 13.

[0066] Understandably, during centrifugation, the centrifuge chamber remains closed. Before or after centrifugation, the top cover 192 of the centrifuge chamber 191 opens to allow the microcolumn gel card 13 to be placed into or removed from the centrifuge chamber. Traditional centrifuges require a robotic arm to open and close the cover, resulting in a complex structure and cumbersome operation. In this invention, the centrifuge 19 has an automatic cover-opening function. When the microcolumn gel card 13 needs to be transferred into or out of the centrifuge chamber, the top cover 192 automatically opens. The first transfer module 12 and the third transfer module 21 only need to transfer the microcolumn gel card 13, without needing to consider opening the centrifuge 19 cover. This simplifies the movement path of the third transfer module 21 and improves the working efficiency of the blood typing analyzer.

[0067] Specifically, refer to Figure 13 Centrifuge 19 includes a chamber 191 and a top cover 192. The chamber 191 contains a centrifuge cavity. The top cover 192 seals the top of the centrifuge cavity in the chamber 191 and has an opening communicating with the centrifuge cavity. Centrifuge 19 also includes a cover-opening mechanism, which includes a cover 194 and a cover-opening drive component 195. The cover 194 is movably connected to the top cover 192. The cover-opening drive component 195 is connected to the cover 194 and is used to drive the cover 194 to move relative to the top cover 192, thereby opening or closing the opening. The movement of the cover 194 relative to the top cover 192 is not limited to rotation or sliding.

[0068] In some embodiments, such as Figure 3 and Figure 12 As shown, the blood typing analyzer also includes an incubation module 22, which provides a suitable incubation environment for antibody screening, crossmatching, and other detection experiments requiring incubation. The incubation module 22 is located in the second operating space 102 and contains multiple incubation tanks. Microcolumn gel cards 13 can be placed in these tanks. The incubation module 22 provides a suitable temperature incubation environment for the microcolumn gel cards 13. After incubation, the microcolumn gel cards 13 can be transferred to a centrifuge 19 for centrifugation. In one embodiment, the incubation module 22 is located within the card entry area 106 and between adjacent new card drawers 107. The incubation module 22 extends along a second direction to fully utilize the space in the second operating space 102 along this direction. After incubation, the microcolumn gel cards 13 are transferred by the first transfer module 12 to the centrifuge 19 for centrifugation.

[0069] Reference Figure 12 The card insertion area 106 also includes a half-card slot 1063, which is used to store half-cards. A half-card is defined as a micropillar gel card 13 in which some of the detection wells 131 have been used, and the remaining detection wells 131 can be used for other samples. When the half-card is read and there are no questions about the reading result, the first transfer module 12 transfers the half-card to the half-card slot 1063 for use in the next experiment, saving detection costs.

[0070] The half-card slot 1063 can be provided with a card slot for holding the micropillar gel card 13. The card slot at the half-card slot 1063 can be set inside the new card drawer 107 and arranged side by side with the card holder slot 11 for placing new cards, so that the operator can take out and put in the half card by pulling out the new card drawer 107 for maintenance. The half-card slot 1063 can be set in the card holder slot 11 of different second space units 1061.

[0071] In one embodiment, the card receiving area 106 includes an abnormal card slot 1064, which has a slot for placing abnormal cards. An abnormal card is defined as a microcolumn gel card 13 being transferred by the first transfer module 12 and the third transfer module 21 when an abnormal situation occurs in the blood typing analyzer. Abnormal situations may include blood typing analyzer malfunction or power failure. After the abnormal situation is resolved, the instrument is powered on again, and the first transfer module 12 and the third transfer module 21 directly transfer the abnormal card to the abnormal card slot 1064 for operator inspection, or for verification or retesting via the system.

[0072] Reference Figure 3 and Figure 12 The blood typing analyzer also includes a quality detection module 23, which is located in the second operating space 102. The quality detection module 23 is used to perform quality detection on the microcolumn gel card 13 to be sampled, such as detecting whether there are quality problems such as dry glue, air bubbles, and impurities in the microcolumn gel card 13. The microcolumn gel card 13 to be sampled is transferred from the first transfer module 12 to the quality detection module 23. If the microcolumn gel card 13 passes the quality detection, the first transfer module 12 continues to transfer the microcolumn gel card 13 to the lifting transfer module 18, and the lifting transfer module 18 transports the microcolumn gel card 13 to the first operating space 101 to continue to perform puncture, sample addition and other procedures. If the microcolumn gel card 13 fails the quality test, the first transfer module 12 will transfer the unqualified microcolumn gel card 13 to the card box in the original card box slot 11 and mark it through the system so that the operator can further process the marked card. The unqualified microcolumn gel card 13 will no longer be used for testing, thus ensuring the accuracy of blood typing analysis. The marking method of the unqualified microcolumn gel card 13 is not limited to color, text, light or their combination marking.

[0073] Furthermore, multiple quality detection modules 23 can be set, and one quality detection module 23 can be set in each second space unit 1061, which shortens the transfer path of the microcolumn gel card 13 and improves the working efficiency of the blood typing analyzer.

[0074] like Figure 12In the embodiment shown, the quality detection module 23 is disposed on the rear side of the lifting and transferring module 18 along the second direction, and the two are disposed adjacent to each other. Therefore, the quality detection module 23 and the lifting and transferring module 18 are relatively close. If the microcolumn gel card 13 passes the quality detection, the first transfer module 12 can quickly transfer the microcolumn gel card 13 to the lifting and transferring module 18, which can further improve the transfer efficiency of the microcolumn gel card 13.

[0075] Reference Figure 1 and Figure 2 The rack 10 includes a third platform 110, which is located below the second platform 104, and defines a third operating space 109 between the third platform 110 and the second platform 104. (See reference...) Figure 15 The blood typing analyzer also includes a movable frame 24 arranged along a first direction. The movable frame 24 is movably disposed in the third operating space 109 and can enter and exit the third operating space 109. Each movable frame 24 carries at least one material container 25, which can follow the movable frame 24 in and out of the third operating space 109 for the operator to replace and maintain. The movement of the movable frame 24 within the third operating space 109 is not limited to this. The movable frame 24 is slidably connected to the third platform 110 along a second direction, and the operator can push and pull the movable frame 24 along the second direction to move it in and out of the third operating space 109. The movable frame 24 is disposed at the front of the third operating space 109 for easy pushing and pulling by the operator.

[0076] The material container 25 is used to store discarded microcolumn gel cards 13, cleaning solution for cleaning the sample needle 161, and waste liquid after cleaning. The material container 25 used to store discarded microcolumn gel cards 13 is defined as the waste card container, the material container 25 used to store the cleaning solution for the sample needle 161 is defined as the washing solution container, the material container used to store the maintenance solution for the sample needle 161 is defined as the maintenance solution container, and the material container 25 used to store the cleaning waste liquid is defined as the waste liquid container. At least one waste card container, washing solution container, waste liquid container, and maintenance solution container are provided. The waste card container is located directly below the interpretation module 20 so that the discarded microcolumn gel cards 13 in the interpretation module 20 can fall into the waste card container for collection.

[0077] Specifically, refer to Figure 16The interpretation module 20 includes a base plate 201, an interpretation unit 202, a card holder assembly 203, and an unlocking unit. The card holder assembly 203 is movably disposed above the base plate 201. The interpretation unit 202 is mounted above the base plate 201 and faces the card holder assembly 203. The interpretation unit 202 is used to acquire images of the micropillar gel card 13 to be tested. The base plate 201 has a vertically penetrating card disposal slot 2011, which is located directly above the waste card bin and away from the initial position of the card holder assembly 203. The card holder assembly 203 includes an openable clamping unit 205, which is used to support and fix the micropillar gel card 13. The unlocking unit is located on the moving path of the card holder assembly 203 so that when the card holder assembly 203 moves to the card disposal slot 2011, it triggers the clamping unit 205 to open, allowing the micropillar gel card 13 to fall into the waste card bin through the card disposal slot 2011.

[0078] The microcolumn gel card interpretation process is as follows: The card holder assembly 203 is in its initial position. The microcolumn gel card to be interpreted is placed on the card holder assembly 203. The interpretation unit 202 acquires an image of the microcolumn gel card 13 to be tested. After the microcolumn gel card 13 is interpreted, if the interpretation result is satisfactory and the microcolumn gel card 13 is not a half-card, the current microcolumn gel card 13 must be discarded. The card holder assembly 203 then moves towards the interpretation unit 202 carrying the microcolumn gel card 13. When the card holder assembly 203 moves to the card discarding port 2011, the clamping unit 205 is triggered and opens, causing the microcolumn gel card 13 to lose support and fall from the card discarding port 2011 into the waste card bin. The card discarding action is seamless and does not require an additional card-grabbing robotic arm, further improving the working efficiency of the blood typing analyzer.

[0079] Reference Figure 5 and Figure 11 The blood typing analyzer also includes a washing station 26, which is located in the first operating space 101. The sample dispensing mechanism 16 includes a dispensing needle 161, which is used to draw liquid into the detection hole 131 of the microcolumn gel card 13 or the sample container. The washing station 26 has a washing tank for the dispensing needle 161 to be inserted into. The washing tank is connected to at least one material tank 25 through a pipeline. For example, the washing tank is connected to a washing solution tank and a waste liquid tank through a pipeline. The washing solution tank is used to supply cleaning solution to the washing tank for cleaning the dispensing needle 161 and the pipeline. The waste liquid formed after cleaning is discharged to the waste liquid tank through a pipeline. The operator can pull out the washing solution tank and the waste liquid tank from the third operating space 109 by pulling out the movable frame 24, add new cleaning solution to the washing solution tank, or discharge the waste liquid in the waste liquid tank.

[0080] Understandably, there are two washing stations 26, one in each of the left first spatial unit 1051a and the right first spatial unit 1051b, to shorten the sample dispensing path of the sample dispensing mechanism 16 and improve the sample dispensing efficiency of the microcolumn gel card 13. Furthermore, there are two washing solution tanks, each connected to one of the two washing stations 26 via pipelines. The two washing solution tanks are placed on two movable racks 24, allowing for independent post-maintenance of each tank. Additionally, a protective solution tank can be placed behind the washing solution tank. Both the protective solution tank and the aspiration tank are located on the same movable rack 24 and supply cleaning and maintenance solutions to the same washing station 26.

[0081] In one embodiment, reference is made to Figure 15 The blood typing analyzer also includes a forced-flow pump 27, which is located in the third operating space 109. For example, the forced-flow pump 27 can be installed on top of the third platform 110. The forced-flow pump 27 is connected to a pipeline connecting the waste liquid tank and the washing tank. The forced-flow pump 27 can extract the waste liquid formed in the washing station 26 and discharge it into the waste liquid tank, making the discharge of waste liquid in the washing tank more thorough. The forced-flow pump 27 can be located on the rear side of the third platform 110, behind the movable frame 24. (Refer to...) Figure 5 and Figure 7 The blood typing analyzer also includes an infusion pump, which is placed inside a pump and valve box 28 located at the rear of the first operating space 101. The infusion pump is connected to a pipeline that connects the washing tank and the washing solution tank, and when cleaning the sample needle 161, it draws the cleaning solution from the washing solution tank and delivers it to the washing tank.

[0082] Reference Figure 15 When maintaining the washing solution tank and waste liquid tank, the operator can pull out the movable frame 24 forward to remove the pipeline from the washing solution tank and waste liquid tank and place it into the connecting container 29 on the back of the movable frame 24 to prevent residual cleaning solution or waste liquid in the pipeline from dripping into the blood typing analyzer.

[0083] The blood typing analyzer also includes a power control box 30, which is located at the bottom of the rack 10. Specifically, the power control box 30 is situated in the third operating space 109 and fixed to the top of the third platform 110. The power control box 30 is located behind the movable frame 24 and is used to provide power to the various modules of the blood typing analyzer and to distribute data. The blood typing analyzer also includes a control module 31, which can be configured as a computer. The control module 31 is located in the third operating space 109. For example, the control module 31 and the movable frame 24 are arranged along a first direction and are located at the front of the third operating space 109, facilitating maintenance of the control module 31 by operators at the front of the rack 10.

[0084] It should be noted that the blood typing analyzer of the present invention is configured to include a first operating space 101, a second operating space 102, and a third operating space 109 distributed vertically. On the one hand, it can make full use of the vertical space and allocate different working modules to different operating spaces according to their functions and workflows, thereby reducing the footprint of the blood typing analyzer and improving its working efficiency. On the other hand, the layout of each layer of operating space conforms to human operating habits, making the operation of the blood typing analyzer more convenient. For example, the waste card bin is set at the lowest position (third operating space 109) to facilitate the microcolumn gel card 13 to fall by gravity; the display screen is set at a high position (above the first platform 103) to facilitate the operator to operate and view information while standing; the new card drawer 107 is set in the middle layer (second operating space 102), and the test tube rack 14 is set at the upper layer (first operating space 101) to facilitate the operator to deliver samples or cards while standing.

[0085] In addition, such as Figure 14 As shown, the first transfer module 12 includes a barcode scanning unit 121 and a second gripping mechanism 122. The second gripping mechanism 122 is used to grip the microcolumn gel card 13. The barcode scanning unit 121 is located on one side of the second gripping mechanism 122 and is used to scan the barcode of the microcolumn gel card 13. While the second gripping mechanism 122 grips the microcolumn gel card 13, the barcode scanning unit 121 reads the barcode of the microcolumn gel card 13 to obtain information such as the type of microcolumn gel card 13 and the current detection stage. This allows the gripping and transfer process of the microcolumn gel card 13 to be carried out synchronously, without having to scan the barcode after the microcolumn gel card 13 reaches a specific position. This ensures the accuracy of the information of the current stage of the microcolumn gel card 13 and also improves the working efficiency of the blood typing analyzer.

[0086] In addition, the first transfer module 12 also includes an optical fiber head 123, which is used to detect the position, quantity, type, and other information of the micropillar gel cards 13 in the card holder. Specifically, after the new card drawer 107 is pushed into place, the first transfer module 12 moves along the first direction and the second direction. During this process, the optical fiber head 123 scans the card slots in the card holder. Based on the amount of light reflected from the card slots, it determines whether there are micropillar gel cards 13 placed in the card slots in the card holder, thereby enabling the collection of information such as the type of micropillar gel cards 13, the position of different types of micropillar gel cards 13, and the quantity.

[0087] Reference Figure 5 , Figure 7 and Figure 11 The first platform 103 is equipped with a loading channel 32. After the test tube rack 14 is pushed into the loading channel 32, the sample is loaded. Multiple loading channels 32 are arranged along the first direction, each channel 32 accommodating one test tube rack 14. (Refer to...) Figure 15The first transfer module 12 also includes a photoelectric detection unit 124. The photoelectric detection unit 124 is used to detect whether the test tube rack 14 has completed sample loading and whether there is a test tube rack 14 in the loading channel 32. During the movement of the first transfer module 12, the photoelectric detection unit 124 passes through different loading channels 32 to determine whether sample loading has been completed or whether there is a test tube rack 14 being loaded. The photoelectric detection unit 124 can be used for self-testing of the blood typing analyzer after a power outage and restart. By detecting whether there is a test tube rack 14 in the loading channel 32, the photoelectric detection unit 124 can prompt the operator to take action, preventing repeated loading into the loading slot and causing collision damage to the test tube rack 14.

[0088] The test tube rack 14 is movably connected to the inlet channel 32 along the second direction, thereby enabling the test tube rack 14 to be pushed into or out of the inlet channel 32 along the second direction; in one embodiment, referring to Figure 17 The tube rack 14 includes two guide bars 321 spaced apart along a first direction and extending along a second direction. The tube rack 14 can move between the two guide bars 321, which guide the movement of the tube rack 14. Figure 17 and Figure 18 As shown, the rack entry channel 32 has a vertically penetrating lifting groove 322, which is located between two guide bars 321. That is, the lifting groove 322 vertically penetrates the first platform 103, allowing the second operating space 102 to communicate with the first operating space 101 through the lifting groove 322; Figure 14 As shown, the first transfer module 12 includes a lifting mechanism 125 that can be raised and lowered vertically. The lifting component 1251 of the lifting mechanism 125 can enter the first operating space 101 through the lifting groove 322, thereby lifting the test tube rack 14.

[0089] Reference Figure 19 As shown in Figure (a), each infeed channel 32 is equipped with a limiting part 323. Along the second direction, the test tube rack 14 has an interval between a transfer position and a sample feeding position. The limiting part 323 is used to stop the test tube rack 14 when it moves to the transfer position, providing an infeed instruction to the operator. When the test tube rack 14 begins to feed samples, the operator pushes the test tube rack 14 into the infeed channel 32, as shown in Figure (a). Figure 19 As shown in Figure (a), when the test tube rack 14 enters the feed channel 32 and moves to the transfer position, the test tube rack 14 abuts against the limiting part 323. The test tube rack 14 is prevented from moving further due to the limitation of the limiting part 323. At this time, the operator is instructed to stop pushing the test tube rack 14, and the blood typing analyzer's internal mechanism will automatically inject the sample. Afterwards, as... Figure 19As shown in Figure (b), the lifting mechanism 125 lifts the test tube rack 14 via the lifting groove 322, causing the test tube rack 14 to move upward and disengage from the limiting part 323. The limiting part 323 is released from its restriction in the direction of the test tube rack 14 entering the rack. Then, the first transfer module 12 drives the test tube rack 14 to move a preset distance in the second direction. After that, the lifting mechanism 125 descends. At this time, the test tube rack 14 is in the sample injection position, and the sample injection is completed.

[0090] In traditional techniques, manual direct sample injection is used. Due to human factors, the injection accuracy of the test tube rack 14 is difficult to guarantee. Furthermore, there is a risk of repeated injections due to misoperation, which can lead to collisions and damage to the test tube rack 14. In this invention, a semi-automatic injection method is adopted. The initial stage is manual injection, where the operator pushes the test tube rack 14 to the intermediate position. The subsequent stage is propelled by the first transfer module 12, which moves the test tube rack 14 to the final injection position to complete the final injection. This method is convenient, avoids manual intervention, and has high injection accuracy.

[0091] In some embodiments, such as Figure 19 As shown in Figures (a) and (b), the first operating space 101 is also equipped with a rack entry sensor 324 and a position detection sensor 325. The rack entry sensor 324 is used to sense whether a test tube rack 14 has entered the rack entry channel 32, and the position detection sensor 325 is used to determine whether the test tube rack 14 is placed at the sample injection position.

[0092] The traditional dilution method involves setting up a dilution plate with a dilution tank. A sampling needle 161 draws diluent and sample into the dilution tank, where they mix. The diluent then dilutes the sample. The sampling needle 161 continues to draw the diluted sample for further processing. This method requires the sampling needle 161 to repeatedly inject diluent and sample into the dilution plate, making the operation cumbersome and inefficient.

[0093] In one embodiment of the present invention, reference is made to Figure 12 and Figure 20At least one of the test tube racks 14 is used to hold the dilution strip. The dilution seal 149 is a sample container encapsulated with diluent. The dilution seal 149 includes multiple dilution holes, which can be arranged in multiple rows and columns. Each dilution hole is pre-encapsulated with diluent, which is not limited to saline. The sample dispensing mechanism 16 can draw the sample or reagent to be tested from the sample container and inject it into the dilution hole for dilution. For example, when a sample needs to be diluted, the dispensing needle 161 draws the sample or reagent to be tested, and its end is inserted into the dilution hole to inject the sample or reagent into the dilution hole. The diluent dilutes the sample or reagent. In this embodiment, the dispensing needle 161 can directly inject the sample or reagent into the sample container pre-encapsulated with diluent, eliminating the need for the dispensing needle 161 to draw the diluent, simplifying the dilution process and improving the working efficiency of the blood typing analyzer. Furthermore, the diluent is pre-encapsulated, eliminating concerns about exposure or leakage, and facilitating operation and transportation.

[0094] In this invention, the first transfer module 12, the second transfer module 17, the third transfer module 21, and the puncture module 15 all have transfer objects. The puncture module 15, the first transfer module 12, and the third transfer module 21 need to transfer the microcolumn gel card 13, and the second transfer module 17 needs to transfer the sample application mechanism 16. The driving method of the first transfer module 12, the second transfer module 17, the third transfer module 21, and the puncture module 15 for the transfer objects is not limited to belt drive mechanism, gear and rack drive mechanism, etc. For example, the puncture module 15 includes a first gripping mechanism 151 and a first moving module 154. The first gripping mechanism 151 is used to grip the puncture piece 152, and the first moving module 154 is used to transfer the first gripping mechanism 151. The first moving module 154 can transfer the first gripping mechanism 151 along a first direction, a second direction, and a vertical direction. The transfer along the second direction is achieved by a belt drive mechanism, and the transfer in the first direction and the vertical direction is achieved by a gear and rack drive mechanism.

[0095] Understandably, belt drives offer high stability for object transfer, while the sample loading mechanism 16 requires high positional accuracy to precisely engage with the microcolumn gel card 13, sample container, etc. Given that long-term belt drives may loosen or slip, affecting transfer accuracy, in one embodiment of the present invention, such as... Figure 6 As shown, an encoder 171 is configured in the second transfer module 17 to overcome the accuracy problem caused by belt loosening; specifically, refer to... Figure 1 , Figure 2 and Figure 6The second transfer module 17 includes a second moving module, which includes a first transmission unit 172 and a second transmission unit 173. The first transmission unit 172 is mounted on the second transmission unit 173, and the second transmission unit 173 can drive the first transmission unit 172 to move along a first direction. The sample dispensing mechanism 16 is mounted on the first transmission unit 172, and the first transmission unit 172 can drive the sample dispensing mechanism 16 to move along a second direction, so that the second moving module can drive the sample dispensing mechanism 16 to move along the first and second directions. Both the first transmission unit 172 and the second transmission unit 173 include a driving component for providing power, such as a motor. Unit 173 includes a synchronous belt 1731, a drive pulley 1732, a driven pulley 1733, and an encoder 171. The synchronous belt 1731 is wound around the drive pulley 1732 and the driven pulley 1733. The encoder 171 is connected to the driven pulley 1733. The encoder 171 can detect the rotation speed, rotation angle, and direction of the driven pulley 1733. When the belt becomes loose, loses steps, or slips, according to the monitoring of the encoder 171, an increasing error occurs between the command position sent to the second moving module and the feedback position. Based on the feedback, the controller increases the output torque of the motor or adjusts the control signal to gradually eliminate the error, making the position transfer of the sampling mechanism 16 more accurate and improving the sampling accuracy.

[0096] Reference Figure 1 and Figure 2 The frame 10 has side plates 34 along its side in the first direction, positioning the side plates 34 on the left and right sides of the blood typing analyzer. The side plates 34 are located outside the first operating space 101, the second operating space 102, and the third operating space 109, making them exposed. (Refer to...) Figure 21 The side panel 34 includes a transparent panel 341 and a light strip 342 bent into a preset shape. The light strip 342 is fixed to the inside of the panel 341. The panel 341 is not limited to being made of acrylic or glass. The light strip 342 is flexible and can be bent into a preset shape. When the light strip 342 is powered on, it can emit light. The light shines outward through the panel 341, and the outside of the panel 341 presents a bright mark with a preset shape.

[0097] In some embodiments, the side panel 34 further includes an inner panel 343, which is disposed inside the panel 341, i.e., on the side of the panel 341 facing the first operating space 101. The light strip 342 is sandwiched between the inner panel 343 and the panel 341. The inner panel 343 and the panel 341 can be attached to each other, and the connection method between the inner panel 343 and the panel 341 is not limited to threaded connection, adhesive, snap-fit, etc. Furthermore, at least one of the inner panel 343 and the panel 341 is provided with a groove, which is disposed on the side of the inner panel 343 and the panel 341 facing each other. The groove is concave and its shape is the same as that of the light strip 342. The groove limits the position of the light strip 342. To further enhance the fixing strength of the light strip 342, the light strip 342 can be adhesively attached to the panel 341 and / or the inner panel 343.

[0098] This invention also provides a blood type analysis system, referring to Figure 22 and Figure 23 The blood typing analysis system includes the blood typing analyzer described above. The first operating space 101 of the blood typing analyzer is provided with a sample injection area 105. The test tube rack 14 is located in the sample injection area 105. The blood typing analysis system also includes a main track 35 and at least one sample injection track 36. The main track 35 is located outside the blood typing analyzer. The main track 35 can be connected to the production line so that the sample holder can automatically enter the sample injection area 105 via the main track 35. The difference between the sample holder and the test tube rack 14 is that the sample holder is only used to carry the sample container, while the test tube rack 14 needs to be equipped with a sample injection structure that cooperates with the sample injection track 36. The sample holder includes a multi-unit rack and a single-cup sample holder. The multi-unit rack has multiple sample positions that can carry sample containers, and the single-cup sample holder has one sample position. Each sample position can carry one sample container.

[0099] One end of the sample injection track 36 is provided with an inlet / outlet 363, which is connected to the main track 35. The other end extends into the sample injection area 105. The sample holder can move from the inlet / outlet 363 to the sample injection track 36 via the main track 35, and then enter the sample injection area 105. After the sample container completes sample aspiration in the sample injection area 105, it can move from the sample injection track 36 to the main track 35 via the inlet / outlet 363 to remove it from the sample injection area 105, and return to the production line via the main track 35. That is, the sample holder enters or leaves the sample injection track 36 through the same inlet / outlet 363. The path of the sample holder entering the sample injection area 105 is the same as that of the sample holder leaving the sample injection area 105, but the direction of movement is opposite.

[0100] In some embodiments (this embodiment is applicable to the transport of sample holders in multi-frame configuration), refer to Figure 22The sample inlet track 36 extends along the second direction (i.e., the front-to-back direction), and the extension direction of the sample inlet track 36 is the same as the inlet direction of the test tube rack 14. The sample inlet track 36 and the test tube rack 14 are arranged side by side. The transport direction of the main track 35 to the sample holder can be set to be parallel to or perpendicular to the extension direction of the sample inlet track 36. When the main track 35 is parallel to the extension direction of the sample inlet track 36, the end of the main track 35 directly connects to the inlet / outlet 363 of the sample inlet track 36, and the sample holder moves in a straight line, passing through the main track 35 and the sample inlet track 36 in sequence. When the main track 35 is perpendicular to the extension direction of the sample inlet track 36, such as... Figure 22 As shown, the blood typing system also includes a turntable 37 with slide rails. One end of the slide rails is connected to the end of the main track 35, and the other end is connected to the inlet / outlet 363 of the sample injection track 36. When the sample holder is transported to the turntable 37 via the main track 35, the slide rails are parallel to the extension direction of the main track 35. After the turntable 37 rotates 90°, the slide rails are parallel to the extension direction of the sample injection track 36, and the ends of the slide rails are aligned with the inlet / outlet 363. Finally, the sample holders are transported to the sample injection track 36 via the inlet / outlet 363 and further enter the sample injection area 105. The turntable 37 can be equipped with one or more slide rails. For example, when the turntable 37 includes one slide rail, the slide rail is in a straight line shape; when the turntable 37 includes two slide rails, the two slide rails intersect perpendicularly, forming a cross shape.

[0101] In another embodiment of the blood typing system (which in this embodiment is applicable to the delivery of single-cup sample holders), refer to Figure 23 The blood typing system also includes a main track 35 and at least one sample introduction track 36. The main track 35 is located outside the blood typing analyzer. The same side of the sample introduction track 36 has an inlet 362 and an outlet 363. Both the inlet 362 and the outlet 363 are connected to the main track 35. Part of the sample introduction track 36 extends into the sample introduction area 105. The sample holder includes a single sample position that can hold a sample container. That is, the sample holder can hold a sample container. The sample holder can move from the inlet 362 to the sample introduction track 36 via the main track 35 to enter the sample introduction area 105. After the sample container completes sample aspiration in the sample introduction area 105, it can move from the sample introduction track 36 to the main track 35 via the outlet 363 to remove it from the sample introduction area 105 and return to the production line via the main track 35. In this scenario, the sample holder enters the sample inlet track 36 from the inlet / outlet 363 and exits the sample inlet track 36 from the outlet 363. The path of the sample holder entering the sample inlet area 105 is different from the path of the sample holder exiting the sample inlet area 105.

[0102] In one embodiment, the sample inlet track 36 is U-shaped and includes a connected sample inlet section 364 and a sample outlet section 365. One end of the sample inlet section 364 forms an inlet 362, and one end of the sample outlet section 365 forms an outlet 363. The two are arranged side by side. The sample holder moves in opposite directions in the sample inlet section 364 and the sample outlet section 365. The part where the sample inlet section 364 and the sample outlet section 365 are connected is set as an arc shape so that the sample holder can turn within the sample inlet area 105.

[0103] Similarly, the sample introduction track 36 extends along the second direction. The extension direction of the sample introduction track 36 can be parallel or perpendicular to the extension direction of the main track 35. In the case where the extension direction of the main track 35 is perpendicular to that of the sample introduction track 36, the main track 35 and the sample introduction track 36 are connected by a deflector 38, and the deflector 38 transfers the sample holder transported by the main track 35 to the sample introduction track 36 for continued transport.

[0104] Understandably, in the above embodiments, the main track 35 and the sample inlet track 36 are not limited to conveying the sample holder by belt conveying, roller conveying, etc. The outer surface of the sample container is provided with a barcode. After the sample holder moves to the end of the sample inlet track 36, it is positioned and scanned to determine the detection information of the current sample. The detection information is not limited to the sample source, the type of sample to be analyzed, etc. Subsequently, the sampling needle 161 aspirates the sample in the sample container and injects it into the dilution strip for dilution and mixing. After all the sample containers of the sample holder have completed aspiration, the sample holder returns to the main track 35 along the original path.

[0105] Multiple injection tracks 36 can be provided, with multiple injection tracks 36 arranged side by side within the injection area 105, allowing the sample holder to enter the injection area 105 via different injection tracks 36; for example... Figure 23 As shown, there are two sample injection tracks 36, which are respectively located in the left first space unit 1051a and the right first space unit 1051b. The two second transfer modules 17 can respectively draw samples into the sample containers in the sample holders on the two sample injection tracks 36, which can improve the working efficiency of the sample analysis system.

[0106] In one embodiment, a portion of the infeed channels 32 within the blood typing analyzer's sample infeed area 105 is removed, and an infeed track 36 is installed in the corresponding area. Simultaneously, the sample infeed area 105 retains multiple test tube racks 14 for operators to push the test tube racks 14 into the sample infeed area. The infeed track 36 in the sample infeed area 105 is connected to the main track 35 of the automated production line, allowing the blood typing system to be used independently for sample infeeding, or to be connected to the automated production line and use either the main track 35 or the infeed track 36 for sample infeeding. Understandably, since the sample infeed area 105 retains the test tube racks 14, one or more of these racks can still be designated as emergency test tube racks 14, allowing the blood typing analyzer to prioritize the analysis of emergency samples, thus preserving the emergency function of the blood typing analyzer.

[0107] like Figure 22 and Figure 23 In the embodiment shown, a mixing strip is provided in the central area of ​​the sample injection area 105, and two sample injection tracks 36 are respectively provided on both sides of the mixing strip. The left first spatial unit 1051a and the right first spatial unit 1051b are each provided with multiple parallel test tube racks 14. The sample injection track 36 is located between the test tube rack 14 and the mixing strip. The test tube rack 14 is not limited to being a sample strip, dilution strip, etc.

[0108] This invention also provides a blood typing analysis method, which can be performed using the aforementioned blood typing analyzer. The blood typing analysis method includes the following steps: The first transfer module 12 is controlled to grab the micropillar gel card 13 and identify the barcode of the micropillar gel card 13.

[0109] The first transfer module 12 transfers the successfully identified microcolumn gel card 13 to the lifting transfer module 18. At the same time, the puncture module 15, according to the type of microcolumn gel card 13 and the test items to be tested in the sample, grabs the puncture piece 152 corresponding to the number of puncture holes and moves it above the lifting transfer module 18.

[0110] When the lifting and transfer module 18 carrying the microcolumn gel card 13 rises to the first operating space 101, the puncture module 15 punctures the microcolumn gel card 13.

[0111] After the second transfer module 17 completes the sample dilution and mixing pretreatment, it transfers the pretreated sample into the corresponding detection well 131 of the microcolumn gel card 13. Then, the lifting and lowering transfer module 18 lowers the microcolumn gel card 13 into the second operating space 102. Subsequently, the first transfer module 12 transfers the microcolumn gel card 13 to the centrifuge 19 for centrifugation, and then transfers the centrifuged microcolumn gel card 13 to the interpretation module 20 for interpretation, obtaining the analysis results of a single experiment.

[0112] Understandably, in the above steps, the information obtained after barcode recognition can be used for information recording and traceability in subsequent testing processes; the lifting and transfer module 18 carrying the microcolumn gel card 13 can move upwards simultaneously with the puncture module 15 grasping the puncture piece 152, or they can be performed sequentially. The actions of the first transfer module 12 taking out the microcolumn gel card 13 from the card slot 11 and scanning the barcode, the transfer of the microcolumn gel card 13 from the second operating space 102 to the first operating space 101, the action of the puncture module 15 grasping the puncture piece 152, and the reagent mixing action do not conflict with each other's movement paths and can be performed simultaneously, which can shorten the waiting time and improve the analysis efficiency.

[0113] The sample dilution and mixing pretreatment refers to the following process: During the transfer and puncture of the microcolumn gel card 13, the sample dispensing mechanism 16 moves under the drive of the second moving module. The sample dispensing mechanism 16 picks up the sample from the test tube rack 14 and injects it into the dilution strip for dilution. During the sample dilution process, the test tube rack 14 performs a reagent mixing operation, such as the mixing mechanism of the mixing strip, to mix the reagent. After the microcolumn gel card 13 is punctured, the sample dispensing mechanism 16 picks up the diluted sample and reagent and injects them into the detection well 131 of the microcolumn gel card 13, completing the sample dispensing into the microcolumn gel card 13. During the sample dispensing process, the sample dispensing mechanism 16 can first inject the diluted sample into the detection well 131, and then inject the mixed reagent into the detection well 131.

[0114] In the case where the first operating space 101 includes multiple first spatial units 1051 and the second operating space 102 includes multiple second spatial units 1061, the multiple first spatial units 1051 are arranged horizontally, and the first spatial units 1051 and the second spatial units 1061 correspond vertically. The lifting and transfer module 18 corresponds one-to-one with the first spatial units 1051 and with the second spatial units 1061. The lifting and transfer module 18 can transport the micropillar gel card 13 between the corresponding first spatial units 1051 and second spatial units 1061. Based on the above, the first transfer module 12 can scan the microcolumn gel card 13 in the corresponding working area according to the position of the test tube rack 14 where the sample has been successfully injected. For example, if the test tube rack 14 enters the first spatial unit 1051, the first transfer module 12 will first grab the microcolumn gel card 13 in the second spatial unit 1061 corresponding to the first spatial unit 1051, and then transfer the blood card to the first lifting transfer module 18. The first lifting transfer module 18 will then transport the microcolumn gel card 13 between the vertically corresponding first spatial unit 1051 and the second spatial unit 1061. In this way, the transfer path of the microcolumn gel card 13 is short, which can improve the efficiency of blood typing analysis.

[0115] Based on the above, the blood typing method includes the following steps: First, the position of the first space unit 1051 where the currently injected test tube rack 14 is located within the first operating space 101 is obtained, and the corresponding second space unit 1061 and lifting and transferring module 18 are determined based on the position; then, the first transfer module 12 is controlled to grab the microcolumn gel card 13 in the corresponding second space unit 1051 and transfer it to the corresponding lifting and transferring module 18; at the same time, based on the position of the currently injected test tube rack 14 in the first space unit 0151, the puncture module 15 in the same first space unit 1051 is controlled to grab the puncture piece 152 and move it above the corresponding lifting and transferring module 18.

[0116] The puncture module 15 punctures the microcolumn gel card 13 when the lifting and transfer module 18 carrying the microcolumn gel card 13 rises to the first operating space 101; according to the position of the current sample injection tube rack 14 in the first space unit 1051, the second transfer module 17 in the same first space unit 1051 is controlled to transfer the pretreated sample to the detection hole 131 of the microcolumn gel card 13; then the lifting and transfer module 18 carrying the microcolumn gel card 13 is controlled to descend to the second operating space 1061.

[0117] The second operating space 102 is equipped with a quality inspection module 23. The quality inspection module 23 can detect whether there are quality problems such as dry glue, air bubbles, impurities, and barcode recognition abnormalities in the microcolumn gel card 13. Before the microcolumn gel card 13 is transferred to the lifting and transferring module 18, the blood typing method also includes a quality inspection step for the microcolumn gel card 13. If the microcolumn gel card 13 passes the quality inspection, the first transfer module 12 transfers the microcolumn gel card 13 to the lifting and transferring module 18. If the microcolumn gel card 13 fails the quality inspection, the first transfer module 12 transfers the microcolumn gel card 13 back to the original card box and marks it.

[0118] For situations where not all detection wells 131 of the microcolumn gel card 13 are used after a single experiment, the blood typing method of this application further includes: A half-slot 1063 is set in the second operating space 102. After the interpretation module 20 completes the interpretation, if there is no doubt about the interpretation result and there are unused detection holes 131 in the current microcolumn gel card 13, the first transfer module 12 is controlled to transfer the microcolumn gel card 13 to the half-slot 1063 for use in the next experiment, saving detection costs. If there is no doubt about the interpretation result and all detection holes 131 in the current microcolumn gel card 13 have been used, the interpretation module 20 discards the interpreted microcolumn gel card 13 into the material container 25 in the third operating space 109. The microcolumn gel card 13 needs to be transferred again through the first transfer module 12, which can simplify the operation complexity of the first transfer module 12 and improve the analysis efficiency. If there is doubt about the interpretation result, the first transfer module 12 is controlled to transfer the interpreted microcolumn gel card 13 to the original card box, mark it, and display it on the display screen for the operator to check and re-test. Situations where the interpretation result is questionable include: the detection well 131 cannot agglomerate, the agglomeration phenomenon is not obvious and thus cannot be interpreted, or the barcode scanning of the microcolumn gel card 13 fails.

[0119] In the event of a malfunction during the transfer of the microcolumn gel card 13 in the second operating space 102, such as an emergency stop or power failure of the blood typing analyzer during the transfer of the microcolumn gel card 13 by the first transfer module 12 or the third transfer module 21, the blood typing analysis method of this application includes an abnormal card slot 1064 to temporarily store the abnormal microcolumn gel card 31 in the event of the aforementioned malfunction. Specifically, the blood typing analysis method includes the following steps: When the blood typing analyzer stops or loses power during the transfer of the microcolumn gel card 13 by the first transfer module 12, the first transfer module 12 is controlled to maintain the clamping state of the microcolumn gel card 13. After the blood typing analyzer resumes operation, if the first transfer module 12 is holding the microcolumn gel card 13, the first transfer module 12 is controlled to continue the transfer operation of the microcolumn gel card 13 according to the current detection process of the microcolumn gel card 13, or the microcolumn gel card 13 is transferred to the abnormal card position 1064.

[0120] For example, if a power outage occurs during the transfer of the microcolumn gel card 13 by the first transfer module 12, the microcolumn gel card 13 currently being transferred by the first transfer module 12 is an abnormal card. When the blood typing analyzer regains power, the first transfer module 12 can directly transfer the abnormal card to the abnormal card slot 1064. Understandably, this method eliminates the need to determine the detection stage of the abnormal card; placing the abnormal card in the abnormal card slot 1064 for unified processing reduces the complexity of data processing and improves the fault repair efficiency of the blood typing analyzer.

[0121] Alternatively, the processing steps of the microcolumn gel card 13 can be traced to obtain the current processing stage of the microcolumn gel card 13, and then the microcolumn gel card 13 can be processed in the next step, realizing the automated processing of abnormal cards, avoiding waste of detection procedures and microcolumn gel cards 13, and improving the detection efficiency of the blood typing analyzer; for example, such as Figure 14 As shown, the barcode on the micropillar gel card 13 is scanned by the barcode scanning unit 121 mounted on the first transfer module 12 to obtain the current detection stage of the micropillar gel card 13, and then the first transfer module 12 transfers the micropillar gel card 13 to the next process for further processing. For example, if the microcolumn gel card 13 has not yet been sampled, and the first transfer module 12 experiences a power outage during the transfer of the microcolumn gel card 13 to the lifting transfer module 18, then after power is restored, the barcode of the microcolumn gel card 13 is scanned by the scanning unit 121 to obtain the current detection stage of the microcolumn gel card 13, allowing the first transfer module 12 to continue transferring the microcolumn gel card 13 to the lifting transfer module 18; or, if the microcolumn gel card 13 has already been sampled, and the first transfer module 12 experiences a power outage during the transfer of the microcolumn gel card 13 to the centrifuge 19, then after power is restored, the first transfer module 12 continues transferring the microcolumn gel card 13 to the centrifuge 19; or, if the microcolumn gel card 13 has already been sampled, and the first transfer module 12 experiences a power outage during the transfer of the microcolumn gel card 13 to the incubator 18 ...... If a power outage occurs during the transfer of the micropillar gel card 13 by module 22, the first transfer module 12 will continue to transfer the micropillar gel card 13 to the incubation module 22 after the power is restored; or, if the micropillar gel card 13 has been read and the reading result is unambiguous, and the micropillar gel card 13 is a half-card, and a power outage occurs when the first transfer module 12 is transferring the micropillar gel card 13 to the half-card position 1063, the first transfer module 12 will continue to transfer the micropillar gel card 13 to the half-card position 1063 after the power is restored; or, if the micropillar gel card 13 has been read and the reading result is ambiguous, and a power outage occurs when the first transfer module 12 is transferring the micropillar gel card 13 to the original card box, the first transfer module 12 will continue to transfer the micropillar gel card 13 to the original card box after the power is restored.

[0122] The blood typing analysis method also includes the following steps: when the blood typing analyzer stops or loses power during the transfer of the microcolumn gel card 13 by the third transfer module 21, the third transfer module 21 maintains the clamping state of the microcolumn gel card 13; after the blood typing analyzer resumes operation, if the third transfer module 21 is still clamping the microcolumn gel card 13, it controls the third transfer module 21 to continue the transfer operation of the microcolumn gel card 13 according to the current detection progress of the microcolumn gel card 13. Alternatively, the third transfer module 21 can be controlled to place the microcolumn gel card 13 into the reading module 20, and the reading module 20 can then drop the microcolumn gel card 13 into the material bucket 25 of the third operating space 109. Alternatively, the third transfer module 21 and / or the first transfer module 12 can be controlled to transfer the microcolumn gel card 13 to the abnormal card position 1064.

[0123] For example, if a power outage occurs during the transfer of the microcolumn gel card 13 by the third transfer module 21, the microcolumn gel card 13 currently being transferred by the third transfer module 21 is an abnormal card. When the blood typing analyzer is powered back on, the third transfer module 21 transfers the microcolumn gel card 13 to the abnormal card position 1064. Alternatively, the third transfer module 21 may first transfer the microcolumn gel card 13 to the interpretation module 20, and then the first transfer module 12 may transfer the microcolumn gel card 13 to the abnormal card position 1064.

[0124] Alternatively, the barcode on the micropillar gel card 13 can be scanned by the barcode scanning unit 121 mounted on the third transfer module 21, or the barcode on the micropillar gel card 13 can be scanned directly by the barcode scanning unit 202 of the interpretation module 20 to obtain the current detection stage of the micropillar gel card 13, and then the micropillar gel card 13 can be transferred to the next process for further processing by the third transfer module 21 or the first transfer module 12. For example, if the microcolumn gel card 13 has been centrifuged but not yet interpreted, and a power outage occurs during the transfer of the microcolumn gel card 13 from the third transfer module 21 to the interpretation module 20, then after power is restored, the third transfer module 21 will transfer the microcolumn gel card 13 to the interpretation module 20 for barcode scanning to obtain the current detection stage of the microcolumn gel card 13, and the interpretation module 20 will continue to interpret the microcolumn gel card 13; or, after power is restored, the third transfer module 21 will transfer the microcolumn gel card 13 to the interpretation module 20 for barcode scanning. If the microcolumn gel card 13 has been interpreted, the interpretation module 20 will discard the microcolumn gel card 13 into the material container 25.

[0125] In one specific embodiment, the blood typing method includes the following steps: After the blood typing analyzer is powered on, each module (including the transfer module, puncture module 15, test tube rack 14, card holder slot 11, etc.) performs initial position confirmation. The first transfer module 12 scans the new card drawer 107 to obtain information such as the position and type of the microcolumn gel card 13 in the card holder slot 11. When the test tube rack 14 is used for sample feeding, the operator pushes the test tube rack 14 into the feed channel 32. When the test tube rack 14 is stopped by the limiting part 323, the test tube rack 14 moves to the transfer position. The lifting mechanism 125 lifts the test tube rack 14 upward and drives the test tube rack 14 to continue moving into the feed channel 32. After the test tube rack 14 moves a preset distance, the lifting mechanism 125 descends and places the test tube rack 14 in the feed channel 32. At this time, the test tube rack 14 is in the sample feeding position, and the feeding of the test tube rack 14 is completed.

[0126] After the test tube rack 14 is inserted, a priority working area is set according to the insertion position of the test tube rack 14. The first transfer module 12 grabs the microcolumn gel card 13 in the card slot 11 of the corresponding area. During the process of grabbing the microcolumn gel card 13, the first transfer module 12 scans the code to confirm the microcolumn gel card 13, and then transfers it to the quality inspection module 23 for quality inspection. If there is no quality problem with the microcolumn gel card 13, the first transfer module 12 grabs the microcolumn gel card 13 at the quality inspection module 23 and transfers the microcolumn gel card 13 to the lifting and transferring module 18.

[0127] When the micropillar gel card 13 is transferred between the second operating space 102 and the lifting and transfer module 18, the puncture module 15 grabs the puncture piece 152 in the needle box assembly 153 and moves the puncture piece 152 to the top of the lifting and transfer module 18. During the upward movement of the lifting and transfer module 18, the puncture piece 152 punctures the encapsulation film of the micropillar gel card 13 and completes the puncture.

[0128] During the transfer and puncture process of the microcolumn gel card 13, the mixing strip mixes the reagent, while the second transfer module 17 drives the dispensing needle 161 to the washing station 26 for cleaning. Then, the dispensing needle 161 draws the sample from the sample strip and injects it into the dilution strip for dilution. After the sample is diluted, the dispensing needle 161 draws the diluted sample and injects it into the detection well 131 of the microcolumn gel card 13. Finally, the second transfer module 17 drives the dispensing needle 161 to the washing station 26 for cleaning. The mixing strip stops mixing. After cleaning, the dispensing needle 161 draws the reagent from the mixing strip and injects the reagent into the detection well 131 of the microcolumn gel card 13. Then, the second transfer module 17 transfers the dispensing needle 161 to the washing station 26 again for cleaning.

[0129] After the microcolumn gel card 13 is loaded with sample, the lifting and lowering transfer module 18 lowers the microcolumn gel card 13. The first transfer module 12 transfers the microcolumn gel card 13 to the centrifuge 19 for centrifugation. According to the current sample detection requirements, the first transfer module 12 can first transfer the microcolumn gel card 13 to the incubation module 22 for incubation, and then transfer the microcolumn gel card 13 after incubation to the centrifuge 19 for centrifugation. After the microcolumn gel card 13 is centrifuged, the third transfer module 21 grabs the microcolumn gel card 13 in the centrifuge 19 and transfers the microcolumn gel card 13 to the interpretation module 20 for interpretation.

[0130] If the interpretation result is unambiguous and the micropillar gel card 13 is not a half-card, the interpretation module 20 will drop the micropillar gel card 13 into the material cylinder of the third operating space 109; if the interpretation result is unambiguous and the micropillar gel card 13 is a half-card, the first transfer module 12 will transfer the micropillar gel card 13 to the half-card position 1063; if the interpretation result is ambiguous, the first transfer module 12 will transfer the micropillar gel card 13 to the original card slot 11 and mark it.

[0131] In the description of this specification, the references to terms such as "one embodiment," "some embodiments," "illustrative embodiment," "example," "specific example," or "some examples," etc., indicate that a specific feature, structure, material, or characteristic described in connection with that embodiment or example is included in at least one embodiment or example of the invention. In this specification, the illustrative expressions of the above terms do not necessarily refer to the same embodiment or example. Furthermore, the specific features, structures, materials, or characteristics described may be combined in any suitable manner in one or more embodiments or examples.

[0132] The embodiments of the present invention have been described in detail above with reference to the accompanying drawings. However, the present invention is not limited to the above embodiments. Within the scope of knowledge possessed by those skilled in the art, various changes can be made without departing from the spirit of the present invention.

Claims

1. A blood typing analyzer, characterized in that, include: The rack has a first operating space and a second operating space inside, with the first operating space located above the second operating space; A card slot is provided in the second operating space. The card slot is used to place a card containing a micropillar gel card. The micropillar gel card has multiple detection holes, and the detection holes are sealed by an encapsulation film. The first transfer module is located in the second operating space and is used to pick up, place and transfer micropillar gel cards within the second operating space. A centrifuge, located in the second operating space, is used to centrifuge the microcolumn gel card; The interpretation module, located in the second operating space, is used to interpret the micropillar gel card; The lifting and transferring module includes a supporting component, which is capable of carrying the micropillar gel card transferred by the first transferring module and lifting and lowering between the first operating space and the second operating space to transfer the micropillar gel card between the first operating space and the second operating space. A puncture module is disposed in the first operating space. The puncture module includes a clamping member and a puncture member. The clamping member is used to clamp the puncture member so that the puncture member punctures the encapsulation film of the micropillar gel card carried on the carrier component. A test tube rack is provided in the first operating space. The test tube rack is used to place sample containers, and the sample containers are used to store liquids. The second transfer module is located in the first operating space and is used to aspirate liquid into the detection well or sample container of the microcolumn gel card.

2. The blood typing analyzer according to claim 1, characterized in that, The puncture module includes a needle box assembly, a first gripping mechanism, and a first moving module. The needle box assembly includes a puncture needle seat for supporting the puncture component. The first gripping mechanism is used to grip the puncture component and is mounted on the first moving module. The first moving module is used to drive the first gripping mechanism to move within the first operating space, so that the first gripping mechanism moves above the needle box assembly to grip the puncture component, or moves above the supporting component for the puncture component to puncture the encapsulation film. The lifting and transfer module also includes a lifting drive mechanism, which is connected to the carrier component and can drive the carrier component to rise and fall, so that when the first gripping mechanism moves above the carrier component, it drives the carrier component to rise, so that the puncture member punctures the sealing film. Optionally, the first operating space includes a plurality of first space units, which are arranged horizontally, and each first space unit is provided with at least one second transfer module, at least one puncture module and a plurality of test tube racks; Optionally, the second operating space includes multiple second space units, which are arranged horizontally. Each second space unit is provided with multiple card slots and at least one first transfer module. The blood type analyzer includes multiple lifting and lowering transfer modules, which correspond one-to-one with the second space units. The first transfer module in the second space unit transfers the microcolumn gel card between the card slot and the corresponding lifting and lowering transfer module. And / or, each of the lifting and transferring modules includes multiple of the load-bearing components, and the lifting and lowering of the multiple load-bearing components are independent of each other; Optionally, the first operating space includes multiple first spatial units arranged horizontally, each first spatial unit containing at least one second transfer module, at least one puncture module, and multiple test tube racks; the second operating space includes multiple second spatial units arranged horizontally, each second spatial unit containing multiple card slots and at least one first transfer module, the first transfer module in the second spatial unit transferring microcolumn gel cards between the card slot and the corresponding lifting transfer module, the first spatial unit and the second spatial unit corresponding vertically; the blood typing analyzer includes multiple lifting transfer modules, the lifting transfer modules being capable of transferring microcolumn gel cards between corresponding first spatial units and second spatial units.

3. The blood typing analyzer according to claim 1, characterized in that, The second operating space includes a card feeding area and a detection area. The card slot is placed in the card feeding area, and the centrifuge and the reading module are arranged in the detection area. The centrifuge and the reading module are arranged along a first direction, and the detection area is located on one side of the card feeding area along a second direction. The first direction, the second direction, and the vertical direction are perpendicular to each other. The blood typing analyzer also includes a third transfer module, which is located in the second operating space and is capable of transferring microcolumn gel cards within the detection area. The first transfer module is capable of transferring microcolumn gel cards between the lifting transfer module and the centrifuge, and between the interpretation module and the card insertion area.

4. The blood typing analyzer according to claim 3, characterized in that, The card insertion area includes a half-card slot, which is used to store a half-card. The half-card is a micropillar gel card with some detection holes already used. The first transfer module is used to transfer the half-card from the interpretation module to the half-card slot. Optionally, the frame further includes a third operating space located below the second operating space, and the third operating space is provided with at least one material hopper; The judgment module includes a base plate, a judgment unit, a card holder assembly, and an unlocking unit. The card holder assembly is movably disposed above the base plate. The judgment unit is installed above the base plate and faces the card holder assembly. The base plate has a vertically penetrating card discarding slot, which is located directly above the material barrel. The card holder assembly includes an openable clamping unit for clamping the micropillar gel card. The unlocking unit is located on the moving path of the card holder assembly so as to trigger the clamping unit to open when the card holder assembly moves to the card discarding port, so that the micropillar gel card falls into the material barrel through the card discarding port. Optionally, the frame further includes a third operating space located below the second operating space. The blood typing analyzer also includes multiple movable frames arranged along a first direction, which are movably disposed within the third operating space to enter and exit it. Each movable frame carries at least one material container. The first direction is perpendicular to the vertical direction. At least one of the material bins is located below the interpretation module, and the material bin is used to store microcolumn gel cards discarded by the interpretation module; And / or, the blood typing analyzer further includes a washing station located in the first operating space, the second transfer module including a sampling needle for aspirating liquid into the detection well of the microcolumn gel card or a sample container, the washing station having a washing tank for inserting the sampling needle, the washing tank being connected to at least one of the material tanks via a pipeline, the material tanks being used to supply cleaning solution to the washing tanks, and the washing station being connected to another material tank via a pipeline and discharging cleaning waste liquid to the material tank.

5. The blood typing analyzer according to claim 1, characterized in that, The frame includes a first platform and a second platform arranged vertically at intervals. The first platform is located above the second platform, and a first operating space is formed above the first platform. The test tube rack is movably connected to the first platform. The second operating space is defined between the first platform and the second platform. The card slot is supported by the second platform. The first platform includes multiple inlet channels, and the test tube rack is movably connected to the inlet channel along a second direction. The inlet channel has a lifting groove that runs vertically through it. Each inlet channel is provided with a limiting part. Along the second direction, the test tube rack has a spaced transfer position and a sample insertion position. The first transfer module includes a lifting mechanism that can move vertically. The second direction is perpendicular to the vertical direction. When the test tube rack enters the racking channel and moves to the transfer position, the test tube rack abuts against the limiting part. The lifting mechanism lifts the test tube rack through the lifting groove, causing the test tube rack to disengage from the limiting part. After the first transfer module drives the test tube rack to move a preset distance along the second direction, the lifting mechanism descends, causing the test tube rack to be located at the sample feeding position. Optionally, at least one of the test tube racks is used to carry a dilution strip, the dilution strip being a sample container encapsulated with diluent, the dilution strip including a plurality of dilution holes, each of the dilution holes being encapsulated with diluent, the second transfer module being able to draw the sample to be tested from the sample container and inject it into the dilution hole for dilution; Optionally, the frame is provided with a side plate along the side of the first direction. The side plate includes a transparent panel and a light strip bent into a preset shape. The light strip is fixed to the inside of the panel and can emit light outward through the panel. The first direction is perpendicular to the vertical direction.

6. A blood type analysis system, characterized in that, The blood typing analyzer comprising any one of claims 1 to 5, wherein the first operating space is provided with a sample introduction area, and the blood typing analysis system further comprises: The blood typing analyzer includes a main track and at least one sample inlet track for transporting sample holders. The main track is located outside the blood typing analyzer. One end of the sample inlet track is provided with an inlet and outlet and is connected to the main track. The other end extends into the sample inlet area. The sample holder includes multiple sample positions capable of holding sample containers. The sample holder can move from the inlet and outlet to the sample inlet track via the main track to enter the sample inlet area, and can also move from the inlet and outlet track to the main track at the sample inlet track to exit the sample inlet area. Alternatively, the blood typing system may further include a main track and at least one sample inlet track, the main track and the sample inlet track being used to transport sample holders. The main track is located outside the blood typing analyzer. An inlet and an outlet are provided on the same side of the sample inlet track, both of which are connected to the main track. A portion of the sample inlet track extends into the sample inlet area. The sample holder includes a single sample position capable of holding a sample container. The sample holder can move from the inlet to the sample inlet track via the main track to enter the sample inlet area, and from the sample inlet track to the main track via the outlet to exit the sample inlet area.

7. A blood type analysis method, characterized in that, Performed by the blood typing analyzer according to any one of claims 1 to 5; comprising: The first transfer module is controlled to grasp the micropillar gel card and identify the barcode of the micropillar gel card; The first transfer module transfers the successfully identified microcolumn gel card to the lifting transfer module. At the same time, the puncture module grabs the puncture piece corresponding to the number of puncture holes according to the type of the microcolumn gel card and the test items to be tested in the sample, and moves it above the lifting transfer module. When the lifting and transfer module carries the microcolumn gel card upward to the first operating space, the puncture module punctures the microcolumn gel card. After the second transfer module completes the sample dilution and mixing pretreatment, it transfers the pretreated sample into the corresponding detection well of the microcolumn gel card. The lifting module is controlled to descend to the second operating space carrying the microcolumn gel card; The first transfer module transfers the microcolumn gel card to a centrifuge for centrifugation, and then transfers the centrifuged microcolumn gel card to the interpretation module for interpretation.

8. The blood type analysis method according to claim 7, characterized in that, The first operating space includes multiple first spatial units, and the second operating space includes multiple second spatial units. The first spatial units and the second spatial units correspond one-to-one vertically. The blood type analyzer includes multiple lifting and transferring modules. The lifting and transferring modules correspond one-to-one with the second spatial units and with the first spatial units. The blood type analysis method includes: Obtain the position of the first spatial unit where the test tube rack currently injecting samples is located within the first operating space, and determine the corresponding second spatial unit and lifting and transfer module based on the position; The first transfer module is controlled to grab the microcolumn gel card in the corresponding second spatial unit and transfer it to the corresponding lifting transfer module; at the same time, according to the position of the current sample injection tube rack in the first spatial unit, the puncture module in the same first spatial unit is controlled to grab the puncture piece and move it above the corresponding lifting transfer module. The puncture module is controlled to complete the puncture of the microcolumn gel card when the lifting and transfer module carries the microcolumn gel card to the first operating space; Based on the position of the test tube rack currently being injected in the first spatial unit, the second transfer module within the same first spatial unit is controlled to transfer the pretreated sample to the detection well of the microcolumn gel card; The lifting and transfer module is controlled to descend to the second operating space carrying the microcolumn gel card; Optionally, the blood typing analyzer further includes a quality detection module, which is disposed in the second operating space, and the blood typing analysis method includes: Before the first transfer module transfers the microcolumn gel card to the lifting transfer module, the microcolumn gel card undergoes quality testing. If the microcolumn gel card passes the test, the first transfer module will transfer the microcolumn gel card to the lifting and lowering transfer module. If the microcolumn gel card fails the test, the first transfer module will transfer the microcolumn gel card to the original card box and mark it.

9. The blood type analysis method according to claim 7, characterized in that, The blood typing analyzer further includes a third operating space located below the second operating space, and the second operating space is provided with a semi-locking position. The blood typing analysis method further includes: After the judgment module completes the judgment, if there is no doubt about the judgment result and there are unused detection holes in the current micropillar gel card, the first transfer module is controlled to transfer the micropillar gel card to the half card position; If there is no doubt about the interpretation result, and all the detection wells in the current micropillar gel card have been used, the interpretation module will discard the interpreted micropillar gel card into the material bucket in the third operating space. If there is any doubt about the interpretation result, the first transfer module is controlled to transfer the interpreted micropillar gel card to the original card box and mark it.

10. The blood type analysis method according to claim 7, characterized in that, The second operating space is equipped with an abnormal card slot, and the blood type analysis method includes: When the blood typing analyzer stops or loses power during the transfer of the microcolumn gel card by the first transfer module, the first transfer module is controlled to maintain the clamping state of the microcolumn gel card. After the blood typing analyzer resumes operation, if the first transfer module holds the microcolumn gel card, it controls the first transfer module to continue the transfer operation of the microcolumn gel card according to the current detection progress of the microcolumn gel card, or to transfer the microcolumn gel card to the abnormal card position. And / or, the blood typing analyzer further includes a third transfer module and a third operating space, the third transfer module being disposed in the second operating space and capable of transferring microcolumn gel cards within the detection area, the second operating space having an abnormal card position, and the third operating space having a material container; the blood typing analysis method includes: When the blood typing analyzer stops or loses power during the transfer of the microcolumn gel card by the third transfer module, the third transfer module maintains the clamping state of the microcolumn gel card. After the blood typing analyzer resumes operation, if the third transfer module holds the microcolumn gel card, it controls the third transfer module to continue performing the transfer operation on the microcolumn gel card according to the current detection progress of the microcolumn gel card. Alternatively, the third transfer module can be controlled to place the microcolumn gel card into the interpretation module, and the interpretation module can then drop the microcolumn gel card into the material bucket of the third operating space. Alternatively, the third transfer module and / or the first transfer module can be controlled to transfer the micropillar gel card to the abnormal card position.

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