A traditional Chinese medicine composition for fascia self-healing and a preparation of medicinal liquid and medicinal paste thereof

Abstract

This invention discloses a traditional Chinese medicine composition for fascial self-healing and its prepared liquid and ointment formulations, belonging to the field of external preparations of traditional Chinese medicine. The composition comprises the following components by weight: 10-20 parts of *Lycopodium clavatum*, 10-20 parts of *Clematis chinensis*, 8-15 parts of *Angelica sinensis*, 8-15 parts of *Ligusticum chuanxiong*, 6-12 parts of *Carthamus tinctorius*, 6-12 parts of *Boswellia carterii*, 6-12 parts of *Commiphora myrrha*, 6-12 parts of *Cinnamomum cassia*, 3-8 parts of *Asarum heterotropoides*, and 3-8 parts of *Glycyrrhiza uralensis*. Based on this composition, two dosage forms, a liquid and an ointment, are prepared. The liquid and ointment of this invention require heating at 40-45℃ and massage during use. The heat effect promotes drug penetration, and massage helps loosen fascial adhesions, guiding the superficial fascia to achieve self-relaxation and repair. It specifically relieves fascial tension, stiffness, and adhesions, exhibiting significant self-healing effects and being safe with no side effects. It can be widely applied in the field of fascial conditioning and is suitable for home use and professional physiotherapy institutions.

Description

Technical Field

[0001] This invention relates to the field of traditional Chinese medicine external preparations, and in particular to a traditional Chinese medicine composition for fascia self-healing and the prepared liquid and ointment thereof. Background Technology

[0002] Fascia is a connective tissue that runs through the human body. It is divided into superficial fascia and deep fascia. The superficial fascia is located between the skin and muscles, and plays a role in connecting, cushioning, and protecting muscles and joints. Due to prolonged sitting or standing, improper exercise, and overuse, modern people are prone to tension, stiffness, and adhesions in the superficial fascia, which can lead to muscle soreness, limited mobility, and poor local blood circulation, seriously affecting their health and quality of life.

[0003] Currently, the main methods of myofascial therapy include massage, hot compresses, physical therapy, and topical medications. However, existing technologies have significant shortcomings: simple massage is difficult to penetrate deep into the superficial fascia, and without medication, the fascia relaxes slowly and has poor self-healing effects; ordinary hot compresses can only temporarily relieve surface tension and cannot fundamentally improve fascial adhesions and repair damage; existing topical myofascial therapy medications are mostly analgesic and anti-inflammatory, lacking the ability to specifically promote fascial self-repair and relieve adhesions, and do not combine the synergistic effect of "heating + massage" to maximize the stimulation of the fascia's self-healing potential.

[0004] Traditional Chinese medicine (TCM) external application has the advantages of being gentle, having strong penetrability, and having few side effects. Combining it with heating can promote the penetration of medicinal components into the superficial fascia, and combining it with massage can help the superficial fascia passively relax, thereby guiding it to achieve self-repair. Therefore, developing a TCM composition, liquid, or ointment that is suitable for "heating + massage" and has targeted fascia repair effects has significant practical value in solving the problems of low efficiency and poor effect of fascia self-healing in existing technologies. Summary of the Invention

[0005] The purpose of this invention is to address the deficiencies and shortcomings of existing technologies by providing a traditional Chinese medicine composition for fascial self-healing and its prepared liquid and ointment. Through scientific formulation and combination with heating to promote drug penetration and massage to assist relaxation, the superficial fascia can achieve self-relaxation and repair, relieve fascial tension, stiffness, and adhesion, and fundamentally enhance the fascia's self-healing ability.

[0006] The technical solution adopted by the present invention to solve its technical problem is: a traditional Chinese medicine composition for fascia self-healing, comprising the following components by weight: 10-20 parts of *Lycopodium clavatum*, 10-20 parts of *Herba Clematis chinensis*, 8-15 parts of *Radix Angelicae Sinensis*, 8-15 parts of *Rhizoma Ligustici Chuanxiong*, 6-12 parts of *Flos Carthami*, 6-12 parts of *Radix Boswelliae*, 6-12 parts of *Radix Myrrha*, 6-12 parts of *Radix Cinnamomi*, 3-8 parts of *Radix Asarum*, and 3-8 parts of *Radix Glycyrrhizae*.

[0007] Preferably, the traditional Chinese medicine composition comprises, by weight, 15 parts of *Lycopodium clavatum*, 15 parts of *Clematis chinensis*, 12 parts of *Angelica sinensis*, 12 parts of *Ligusticum chuanxiong*, 9 parts of safflower, 9 parts of frankincense, 9 parts of myrrh, 9 parts of cinnamon twig, 5 parts of *Asarum heterotropoides*, and 5 parts of licorice.

[0008] Furthermore, the herbal composition for fascial self-healing also contains auxiliary ingredients, by weight: 6-12 parts of mugwort and 6-12 parts of ginger. It is used to enhance the effects of warming and unblocking the meridians, dispelling cold and relieving pain, and is suitable for people with fascial tension due to cold and dampness obstruction.

[0009] The formulation mechanism of this traditional Chinese medicine composition is as follows: The formulation of this invention is based on the core principles of "warming and unblocking the meridians, promoting blood circulation and removing blood stasis, relaxing muscles and tendons, and loosening adhesions." Combining the principles of monarch, minister, assistant, and guide in traditional Chinese medicine formulation, the components work synergistically to target the superficial fascia, providing conditions for its self-healing. The principal herbs are *Shenjincao* and *Tougucao*: *Shenjincao* is bitter and pungent in taste, and warm in nature. It can dispel wind and dampness, relax muscles and tendons, and is good at relieving fascial tension and loosening adhesions; *Tougucao* is pungent and bitter in taste, and warm in nature. It can dispel wind and dampness, promote blood circulation and relieve pain, soften hardness and dissipate nodules. It can promote the penetration of drugs into the deep layers of fascia, assist in loosening adhesions, and clear obstacles for fascial self-healing.

[0010] Angelica sinensis, Ligusticum chuanxiong, and Carthamus tinctorius are the assistant herbs: Angelica sinensis nourishes and invigorates blood, regulates menstruation and relieves pain, and can improve local blood circulation in the fascia, providing nutrition for fascia repair; Ligusticum chuanxiong invigorates blood and qi, dispels wind and relieves pain, and can clear meridian blockages and relieve pain caused by fascia stiffness; Carthamus tinctorius invigorates blood and unblocks menstruation, disperses blood stasis and relieves pain, further enhancing the effect of invigorating blood and removing blood stasis, promoting the excretion of fascia metabolic waste and accelerating the repair process.

[0011] Frankincense, myrrh, and cinnamon twig are used as adjuvants: Frankincense and myrrh both have the effects of promoting blood circulation, relieving pain, reducing swelling and promoting tissue regeneration. They can alleviate the inflammatory response after fascial injury and promote the repair of damaged fascial tissue. Cinnamon twig is pungent and sweet in taste and warm in nature. It can induce sweating, relieve muscle tension, and warm and unblock the meridians. When heated, it can enhance the warming and unblocking effect, promote the penetration of drug components, and at the same time assist in massage to relax the fascia.

[0012] Asarum and licorice are the guiding herbs: Asarum is pungent and warm in nature. It can dispel wind and cold, open the orifices and relieve pain, enhance the effect of warming and unblocking the meridians, and relieve soreness caused by fascial tension; Licorice can invigorate qi and replenish the middle jiao, clear heat and detoxify, harmonize the herbs, and moderate the irritation of the herbs in the formula, so that the components can work together and avoid the side effects caused by excessive dosage of a single drug.

[0013] A method for preparing a traditional Chinese medicine liquid for fascial self-healing, using the above-mentioned traditional Chinese medicine composition as raw material, and including the following preparation steps: (1) Raw material pretreatment: Weigh each Chinese herbal medicine component according to the weight parts, remove impurities, wash and dry, then pulverize to 80-100 mesh coarse powder, mix evenly to obtain mixed herbal coarse powder; (2) Extraction: Add 8 to 12 times the total mass of purified water to the mixed medicinal powder, soak for 30 to 60 minutes, heat to boiling and then simmer for 1.5 to 2 hours, filter to obtain the first extract; add 6 to 8 times the total mass of purified water to the filter residue, simmer again for 1 to 1.5 hours, filter to obtain the second extract; (3) Concentration: Combine the two extracts, let stand for 24 hours, take the supernatant, and concentrate under reduced pressure to a relative density of 1.05-1.10 (60℃) to obtain the concentrate; (4) Preparation: Add purified water to the concentrate and adjust the concentration to 20-30g of raw medicinal material per 100mL of concentrate. Stir evenly, filter, sterilize, and then dispense to obtain the medicinal solution for fascia self-healing.

[0014] This invention also protects the traditional Chinese medicine liquid for fascial self-healing prepared by the above preparation method.

[0015] A method for preparing a traditional Chinese medicine ointment for fascial self-healing, using the aforementioned traditional Chinese medicine liquid for fascial self-healing as a raw material, and including the following preparation steps: (1) Matrix preparation: Take 60-80 parts of petrolatum, 10-20 parts of lanolin and 5-10 parts of liquid paraffin, place them in a water bath and heat to 60-70℃, stir evenly to obtain the ointment matrix; (2) Mixing: Slowly add the Chinese herbal medicine liquid to the ointment base while stirring, keeping the temperature at 50-60℃, and stir until the mixture is uniform and forms a fine ointment; (3) Preparation: After cooling to room temperature, dispensing and sterilization, the finished product is obtained.

[0016] This invention also protects the traditional Chinese medicine ointment for fascial self-healing prepared by the above preparation method.

[0017] The traditional Chinese medicine composition of the present invention is used to prepare a topical preparation for fascial self-healing. The preparation type is the above-mentioned liquid or ointment. The preparation needs to be used in conjunction with heating and massage. By utilizing the effects of warming and unblocking the meridians and loosening adhesions, the superficial fascia can be self-healed, relieving the problems of fascial tension, stiffness and adhesions.

[0018] The specific usage method is as follows: 1. Application of the medicinal solution: Heat the medicinal solution to 40-45℃ (warm to the touch but not hot to the skin), and apply it evenly to the areas of tense and stiff fascia, with a thickness of 0.5-1mm; use your palm or a professional massage tool to massage the area with gentle pressing, kneading and stretching, gradually increasing the pressure, for 10-15 minutes each time, 1-2 times a day, for 7-14 days as one course of treatment; 2. Application of the ointment: Apply the ointment evenly to the area of ​​fascia discomfort, with a thickness of 1-2 mm. Apply a warm towel to the area for 5-10 minutes (maintaining a temperature of 40-45℃) to allow the ointment ingredients to fully penetrate. Then massage for 10-15 minutes, using the same massage technique as the liquid medication. Use once daily for 7-14 consecutive days as one course of treatment.

[0019] Core principle: Heating allows the medicinal components in the liquid / ointment to quickly penetrate into the superficial fascia, while the heat effect initially relaxes the fascia and dilates local blood vessels; combined with massage, it further loosens fascial adhesions, relieves fascial tension, and guides the superficial fascia to restore its normal elasticity and tension, thereby achieving self-relaxation and repair of the superficial fascia.

[0020] Compared with the prior art, the present invention has the following significant advantages: 1. Highly targeted and with significant self-healing effects: The formula is specifically designed for problems such as fascial tension, stiffness, and adhesions. The components work synergistically to achieve the effects of warming and unblocking the meridians, promoting blood circulation and removing blood stasis, loosening adhesions, and repairing fascia. Combined with the synergistic effect of "heating + massage", it can quickly guide the relaxation of superficial fascia and stimulate its self-healing potential. Compared with simple massage or ordinary topical drugs, the self-healing efficiency is increased by more than 30%.

[0021] 2. Good dosage form compatibility and convenient use: It provides two dosage forms, liquid and ointment. The liquid is heated before application and the ointment is applied after hot compress. Both are suitable for massage. It can be flexibly selected according to different people (such as sensitive skin, dry skin) and usage scenarios (home, professional physiotherapy institutions). It is convenient and easy to use.

[0022] 3. Traditional Chinese medicine is natural and safe with few side effects: It uses pure traditional Chinese medicine formulas, without the pain-relieving and anti-inflammatory ingredients of Western medicine. It is gentle and non-irritating to the skin and does not cause dependence. It is suitable for long-term use and is suitable for all types of people (except those with allergies).

[0023] 4. Simple preparation process and low cost: The preparation process does not require complex equipment, the extraction, concentration and formulation steps are simple, the raw materials are readily available and the cost is controllable, which facilitates large-scale production and promotion. Detailed Implementation

[0024] The present invention will be further illustrated below with reference to specific embodiments. These embodiments are only some, not all, of the embodiments described herein.

[0025] Example 1: The following components are weighed according to their weight as a traditional Chinese medicine composition for fascial self-healing: 15 parts of *Shenjincao*, 15 parts of *Tougucao*, 12 parts of *Danggui*, 12 parts of *Chuanxiong*, 9 parts of *Honghua*, 9 parts of *Boxiang*, 9 parts of *Moyao*, 9 parts of *Guizhi*, 5 parts of *Xixin*, and 5 parts of *Gancao*.

[0026] Preparation method: Remove impurities from each component, wash and dry them, then pulverize them into 80-mesh coarse powder, mix them evenly, and the traditional Chinese medicine composition is obtained.

[0027] Example 2: The medicinal solution for fascial self-healing, based on the traditional Chinese medicine composition of Example 1, is prepared as follows: (1) Raw material pretreatment: Take 100g of the mixed medicinal material coarse powder prepared in Example 1 and set aside; (2) Extraction: Add 1000mL of purified water to the mixed herbal powder, soak for 45 minutes, heat to boiling and then simmer for 1.5 hours, filter to obtain the first extract; add 700mL of purified water to the residue, simmer again for 1 hour, filter to obtain the second extract; (3) Concentration: Combine the two extracts, let stand for 24 hours, take the supernatant, and concentrate under reduced pressure until the relative density is 1.08 at 60℃ to obtain the concentrate; (4) Preparation: Add purified water to the concentrate and adjust it to contain 25g of raw medicinal material per 100mL of concentrate. Stir well, filter with a 0.22μm filter membrane, sterilize at 121℃ for 15 minutes, and dispense into 100mL / bottle to obtain the finished medicinal liquid.

[0028] Example 3: The ointment for fascial self-healing, based on the traditional Chinese medicine liquid prepared in Example 2, is prepared as follows: (1) Matrix preparation: Take 70g of petrolatum, 15g of lanolin and 8g of liquid paraffin, place them in a water bath and heat to 65℃, stir evenly to obtain the ointment matrix; (2) Mixing: Take 50g of the Chinese medicine liquid prepared in Example 2 and slowly add it to the ointment base while stirring. Keep the temperature at 55℃ and stir for 20 minutes until it is mixed evenly and has a fine ointment. (3) Preparation: Cool the paste mixture to room temperature, dispense into 20g / boxes, and autoclave at 121℃ for 15 minutes to obtain the finished ointment.

[0029] Example 4: A traditional Chinese medicine composition and preparation containing auxiliary ingredients, wherein the traditional Chinese medicine composition contains, by weight: 18 parts of *Lycopodium clavatum*, 18 parts of *Clematis chinensis*, 10 parts of *Angelica sinensis*, 10 parts of *Ligusticum chuanxiong*, 8 parts of *Carthamus tinctorius*, 8 parts of *Boswellia carterii*, 8 parts of *Commiphora myrrha*, 8 parts of *Cinnamomum cassia*, 6 parts of *Asarum heterotropoides*, 6 parts of *Glycyrrhiza uralensis*, 9 parts of *Artemisia argyi*, and 9 parts of ginger. The preparation methods of Examples 2 and 3 are used to prepare a liquid and an ointment, respectively. The usage methods are consistent with those of the liquid and ointment disclosed in this invention, and are suitable for people with cold-dampness obstruction type fascial tension, with more prominent effects in warming and dispersing cold and repairing fascia.

[0030] Effect verification: To further verify the fascia self-healing effect and safety of the liquid and ointment of the present invention, a volunteer verification experiment was conducted. The specific verification plan and results are as follows: 1. Volunteer Selection Criteria Sixty volunteers (aged 25-55, 30 men and 30 women) who meet the following criteria will be selected: ① diagnosed with superficial fascia tension and stiffness, manifested as shoulder, neck / lower back pain and limited mobility, without obvious organic lesions; ② have not used similar conditioning drugs or received physiotherapy / massage in the past month; ③ have no history of allergy to traditional Chinese medicine, skin ulcers or other contraindications; ④ can strictly follow the protocol to complete the 14-day verification without dropping out midway.

[0031] 2. Validate grouping and control conditions Sixty volunteers were randomly divided into three groups (20 people in each group). There were no statistically significant differences in age, gender, and symptom severity among the three groups (P>0.05) to ensure comparability. During the validation period, the three groups maintained the same daily routine, avoided additional myofascial treatments, strictly followed the product usage instructions, and recorded their symptoms. ①Medicated solution application group: The medicated solution prepared in Example 2 of this invention was used and operated according to the usage method disclosed in this invention (the medicated solution was heated to 40-45°C and applied, combined with massage for 10-15 minutes, twice a day) for 14 consecutive days; ② Ointment usage group: The ointment prepared in Example 3 of this invention was used and operated according to the usage method disclosed in this invention (apply hot compress for 5-10 minutes after application, and massage for 10-15 minutes, once a day) for 14 consecutive days; ③ Control group: Commercially available common topical analgesic ointment was used, applied according to the instructions, without heating or massage, once a day for 14 consecutive days.

[0032] 3. Detailed Rules for Judging Results The verification cycle is 14 days. After the cycle, volunteers are divided into three assessment levels based on their symptom improvement to ensure consistent and objective assessment criteria. - Cured: Symptoms of fascial tension and stiffness are completely relieved, muscle soreness in the shoulders, neck, and lower back disappears, movement is free, there is no stiffness when pressed, the elasticity of the superficial fascia returns to normal, and normal work and life can be resumed without any signs of recurrence. - Effective: Significantly reduces symptoms of fascial tension and stiffness, relieves muscle soreness by more than 80%, improves limited mobility, and provides a slight stiffness upon pressure. It does not affect daily work or life, and may cause slight discomfort after occasional exertion. - Ineffective: Symptoms of fascia tension, stiffness, and muscle soreness show no improvement or even worsen, limited mobility is not relieved, and there is obvious stiffness upon palpation, making it impossible to relieve discomfort symptoms normally.

[0033] Overall effectiveness rate = (number of cured + number of effective cases) / total number of people in each group × 100%. At the same time, adverse reactions such as skin irritation and allergies during the verification period of the three groups of volunteers were recorded to assess the safety of the product.

[0034] The statistical results are recorded in the table below: (Table 1) Table 1

[0035] Analysis of verification results: The total effective rate of both the liquid and ointment groups was 95%, significantly higher than that of the control group (55%). The cure rates were 80% and 75%, respectively, indicating that the combination of the liquid and ointment of this invention with heating and massage has a much better fascia repair effect than ordinary topical analgesic ointments. No adverse reactions such as skin irritation or allergies were observed in any of the three groups, indicating that the product is safe, gentle, and has no side effects, making it suitable for long-term use. In addition, a small-scale verification (10 people per group) was conducted on the liquid and ointment prepared using Example 4 (containing mugwort and ginger as auxiliary ingredients) for people with cold-dampness obstruction type fascia tension. Its warming and dispersing effects and fascia repair effects were more prominent than those of Examples 2 and 3, with a total effective rate of up to 98%, further demonstrating the flexibility and optimization advantages of the formulation of this invention.

[0036] The above embodiments are only used to explain the present invention and are not intended to limit the protection of the present invention. Any non-substantial modifications made based on the essential solution of the present invention should fall within the protection scope of the present invention.

Claims

1. A traditional Chinese medicine composition for fascial self-healing, characterized in that, By weight, it includes the following components: 10-20 parts of *Lycopodium clavatum*, 10-20 parts of *Herba Clematis chinensis*, 8-15 parts of *Radix Angelicae Sinensis*, 8-15 parts of *Rhizoma Ligustici Chuanxiong*, 6-12 parts of *Flos Carthami*, 6-12 parts of *Radix Boswelliae*, 6-12 parts of *Radix Myrrha*, 6-12 parts of *Radix Cinnamomi*, 3-8 parts of *Radix Asarum*, and 3-8 parts of *Radix Glycyrrhizae*.

2. The traditional Chinese medicine composition for fascial self-healing according to claim 1, characterized in that, By weight, it includes: 15 parts of *Shenjincao*, 15 parts of *Tougucao*, 12 parts of *Danggui*, 12 parts of *Chuanxiong*, 9 parts of *Honghua*, 9 parts of *Boxiang*, 9 parts of *Moyao*, 9 parts of *Guizhi*, 5 parts of *Xixin*, and 5 parts of *Gancao*.

3. The traditional Chinese medicine composition for fascial self-healing according to claim 1 or 2, characterized in that, It also contains auxiliary ingredients, by weight: 6-12 parts mugwort and 6-12 parts ginger.

4. A method for preparing a traditional Chinese medicine liquid for fascial self-healing, characterized in that: Using the traditional Chinese medicine composition as described in any one of claims 1 to 3 as raw material, and comprising the following preparation steps: (1) Raw material pretreatment: Weigh each Chinese herbal medicine component, remove impurities, wash and dry, then pulverize to 80-100 mesh coarse powder, mix evenly to obtain mixed herbal coarse powder; (2) Extraction: Add 8 to 12 times the total mass of purified water to the mixed medicinal powder, soak for 30 to 60 minutes, heat to boiling and then simmer for 1.5 to 2 hours, filter to obtain the first extract; add 6 to 8 times the total mass of purified water to the residue, simmer again for 1 to 1.5 hours, filter to obtain the second extract; (3) Concentration: Combine the two extracts, let stand for 24 hours, take the supernatant, and concentrate under reduced pressure until the relative density is 1.05 to 1.10 at 60°C to obtain the concentrate; (4) Preparation: Add purified water to the concentrate and adjust the concentration to 20-30g of raw medicinal material per 100mL of concentrate. Stir evenly, filter, sterilize and then package to obtain the finished product.

5. A traditional Chinese medicine liquid for fascial self-healing, characterized in that: It is prepared by the preparation method described in claim 4.

6. A method for preparing a traditional Chinese medicine ointment for fascial self-healing, characterized in that: The preparation method uses the traditional Chinese medicine liquid for fascial self-healing as described in claim 5 as a raw material and includes the following preparation steps: (1) Matrix preparation: Take 60-80 parts of petrolatum, 10-20 parts of lanolin and 5-10 parts of liquid paraffin, place them in a water bath and heat to 60-70℃, stir evenly to obtain the ointment matrix; (2) Mixing: Slowly add the Chinese herbal medicine liquid to the ointment base while stirring, keeping the temperature at 50-60℃, and stir until the mixture is uniform and forms a fine ointment; (3) Preparation: After cooling to room temperature, dispensing and sterilization, the finished product is obtained.

7. A traditional Chinese medicine ointment for fascial self-healing, characterized in that: It is prepared by the method described in claim 6.

8. The use of the traditional Chinese medicine composition according to any one of claims 1 to 3 in the preparation of a topical preparation for fascial self-healing, wherein the preparation type is the liquid of claim 5 or the ointment of claim 7, and the preparation is used in conjunction with heating and massage to promote superficial fascia relaxation, repair fascial damage, and relieve fascial tension, stiffness and adhesion.

9. The application according to claim 8, characterized in that: The heating temperature is 40-45℃, and the massage operation includes gentle pressing, kneading, and stretching. Each operation lasts 10-15 minutes and is used 1-2 times a day.

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