一种带滤膜捕获层的微流控微生物富集检测装置
By employing a micro servo motor to drive the filter membrane plate to tilt and rotate, and a hollowed-out cylinder with a reverse flow-blocking design in the microfluidic microbial enrichment detection device, the problems of uneven wetting of detection reagents and insufficient microbial reaction are solved, thereby improving the sensitivity and accuracy of detection and reducing the risk of false positives and false negatives.
Patent Information
- Authority / Receiving Office
- CN · China
- Patent Type
- Patents(China)
- Current Assignee / Owner
- INST OF BIOLOGY CHINA ACAD OF TESTING TECH
- Filing Date
- 2026-05-12
- Publication Date
- 2026-07-17
AI Technical Summary
Existing microfluidic detection devices based on membrane filtration enrichment suffer from problems such as uneven wetting of detection reagents, insufficient microbial reaction, low detection sensitivity, large result deviation, and susceptibility to false positives and false negatives.
A microfluidic microbial enrichment and detection device with a filter membrane capture layer is adopted. The filter membrane plate is driven to tilt and rotate by a micro servo motor. Combined with the hollow cylinder reverse flow obstruction and split liquid inlet design, it ensures that the detection reagent evenly covers the entire filter membrane and realizes the full and specific reaction between microorganisms and reagents.
It improved the detection signal response value, reduced the risk of false negatives in low-abundance samples, reduced detection errors, and significantly improved the reliability and application value of microfluidic microbial enrichment detection.
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Figure CN122188778B_ABST