Method for preparing a gastric soluble film-coated tablet

Abstract

This invention relates to the field of coated tablet technology, specifically to a method for preparing gastric-soluble film-coated tablets, comprising the following steps: preparation of modified sodium alginate powder, preparation of tablet core, preparation of coating solution, coating, and drying. Modified sodium alginate powder prepared using an optimized process is added to the coating solution. The optimized preparation process of the modified sodium alginate powder includes the following steps. The modified sodium alginate powder preparation process of this invention is optimized, resulting in excellent performance: By optimizing process parameters such as the modifier ratio, reaction temperature, and reaction time, this invention effectively improves the water solubility and film-forming properties of natural sodium alginate. The resulting modified sodium alginate powder exhibits strong adhesion, good film-forming properties, excellent gastric solubility, and stable performance, providing a foundation for the excellent performance of the coating layer.

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