一种皮肤间质液中皮质醇的在体检测微针贴片技术及其制备方法
By using surface-modified in vitro microneedle patch technology, the problems of insufficient sample volume and low sensitivity in microneedle detection technology have been solved, achieving high sensitivity and high accuracy in the detection of cortisol in interstitial fluid of the skin, which is suitable for in vivo detection of trace samples.
Patent Information
- Authority / Receiving Office
- CN · China
- Patent Type
- Applications(China)
- Current Assignee / Owner
- BEIHANG UNIV
- Filing Date
- 2026-06-17
- Publication Date
- 2026-07-17
AI Technical Summary
Existing microneedle detection technology suffers from problems such as insufficient sample size, low detection sensitivity, susceptibility to contamination, and difficulty in achieving rapid in-situ detection of cortisol in interstitial fluid of the skin.
By employing surface-modified in vitro microneedle patches and utilizing plasma treatment and protein coating technology, microneedle patches capable of directly capturing cortisol on the skin surface are prepared, reducing sample volume requirements and achieving high sensitivity and high accuracy detection.
It achieves highly sensitive and accurate in vivo detection of cortisol in interstitial fluid of the skin, without the need for venous blood collection and sample separation, and is suitable for quantitative detection of trace samples.
Smart Images
Figure CN122398293A_ABST