A cell research-oriented experimental process data management method and system

By acquiring the well edge distance and perturbation events in multi-well plate cell experiments, late-mover drift potential and drift contribution values ​​are generated. A reinforcement learning model is used for process management, which solves the problem of inaccurate well data reliability determination in multi-well plate experiments and improves the reliability and traceability of experimental results.

CN122415015APending Publication Date: 2026-07-17

Patent Information

Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Filing Date
2026-04-21
Publication Date
2026-07-17

AI Technical Summary

Technical Problem

In existing cell research and development experiments, it is difficult to uniformly characterize the process disturbance history of different well positions within a multi-well plate, making it difficult to identify the effects of delayed drift, resulting in inaccurate judgment of the reliability of well position data, and affecting the reliability and traceability of experimental results.

Method used

By acquiring the edge distances and disturbance events of each hole in the experimental board, a disturbance event chain is generated, the late drift potential and drift contribution value are calculated, and a reinforcement learning model is used for process governance to generate a management ledger to improve the targeting and temporal consistency of data management.

Benefits of technology

This method enables accurate interpretation of well-level states and identification of drift effects in multi-well plate cell experiments, improving the reliability of experimental data and the traceability of results, and reducing the interference of delayed drift on conclusions.

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Abstract

本发明公开了一种面向细胞研发的实验流程数据管理方法及系统,涉及细胞研发实验数据与流程管理技术领域,包括:获取实验板内各孔位的边缘距离并构建扰动事件链,基于持续时长与记录液量提取迟发漂移势,结合孔位观测值确定漂移贡献值,进一步提取漂移带深度与累计递进量;将漂移带深度、累计递进量和平均漂移强度构建为环境状态并输入强化学习模型,输出流程治理动作;再基于漂移贡献值确定可信系数,完成孔位数据路由处理并生成管理账本。本发明能够识别多孔板细胞实验中边缘向内递进的迟发漂移影响,提高数据分级管理、复核归档和结果分析的可靠性。
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