Application of thalia dealbata in inhibiting PI3K / Akt / mTOR signaling pathway to slow down animal cell senescence
By inhibiting the PI3K/Akt/mTOR and S6Kl signaling pathways, the application of *Heliotropium indicum* in formulations has solved the problem of insufficient antioxidant and anti-inflammatory effects in existing technologies, achieving an effective slowing down of animal cell aging and enhancing its application in drug development.
Patent Information
- Authority / Receiving Office
- CN · China
- Patent Type
- Applications(China)
- Current Assignee / Owner
- GUANGXI UNIV OF CHINESE MEDICINE
- Filing Date
- 2026-06-29
- Publication Date
- 2026-07-24
AI Technical Summary
In existing technologies, the application of *Heliotropium indicum* is limited to its antioxidant and anti-inflammatory effects, failing to specifically regulate related biological factors to effectively slow down aging, thus limiting its application in drug development.
By inhibiting the activity of the PI3K/Akt/mTOR and S6K1 signaling pathways, *Euphorbia hirta* is used in formulations or pharmaceutical compositions to slow down animal cell aging. The crude drug content is 3.75 g/kg to 15 g/kg, and it is administered orally.
Yellow water lily significantly delays the aging process of animal cells by inhibiting the activity of these signaling pathways, improving its efficiency in anti-aging drugs and exhibiting antioxidant, anti-inflammatory and anti-apoptotic effects.
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Figure CN122440705A_ABST