A fungicidal composition containing pyridylmethylcarbamate

Abstract

The present application belongs to the technical field of pesticides, and particularly relates to a kind of fungicidal composition containing fluazinam. A kind of fungicidal composition, the effective component of the fungicidal composition is compounded by triforine and fluazinam, or is compounded by fluazinam and fluazinam. The present application compounds triforine or fluazinam and fluazinam, and it is found through indoor biological activity test that the compound combination has a synergistic effect on rhynchosporium orthosporum causing wheat sharp eyespot in a certain mass ratio range, which helps to improve the control effect on wheat sharp eyespot, and has important significance for the research and development of high-efficiency agents for preventing and treating wheat sharp eyespot.

Description

Technical Field

[0001] This invention belongs to the field of pesticide technology, specifically relating to a fungicide composition containing fluopyram. Background Technology

[0002] Trifluridine is a novel succinate dehydrogenase inhibitor developed by Syngenta. It works by inhibiting succinate dehydrogenase in pathogens, interfering with mitochondrial respiration, leading to the pathogen's inability to synthesize energy normally, and ultimately causing its exhaustion and death, thus achieving disease control. Currently, trifluridine has been found to have good control effects on strawberry wilt, rapeseed sclerotinia stem rot, wheat stem rot, and rice bakanae disease.

[0003] Fluopyram, developed by BASF, is a novel succinate dehydrogenase inhibitor. It is characterized by high efficiency, broad spectrum, long-lasting effect, strong selectivity, and resistance to rain washout. It also exhibits excellent systemic conductivity and provides both preventative and curative effects. This agent can be used for foliar spraying or seed treatment. Currently, fluopyram is registered for use on various crops to control powdery mildew, gray mold, and sheath blight, among other diseases.

[0004] Fluopyram is a novel succinate dehydrogenase inhibitor developed by Syngenta. However, unlike other novel succinate dehydrogenase inhibitors, it introduces a new structure, namely the N-methoxy structure, into its molecule, giving it a broader fungicidal spectrum. Studies have found that fluopyram has good control effects on sclerotinia rot, gray mold, and maize leaf blight.

[0005] Plant diseases cause enormous losses to agricultural production, not only limiting crop yields but also significantly reducing the quality of agricultural products. Using chemical agents is an economical and effective method for controlling plant diseases. In recent years, due to the rapid mutation of pathogens, the resistance of disease-resistant cultivars in major crops is easily lost. Therefore, the synergistic effect and reduced dosage of compound pesticides are of great significance for the prevention and control of crop diseases and for ensuring crop yield and quality.

[0006] The information disclosed in this background section is intended only to enhance the understanding of the overall background of the invention and should not be construed as an admission or in any way implying that the information constitutes prior art known to those skilled in the art. Summary of the Invention

[0007] The purpose of this invention is to provide a bactericidal composition containing fluopyram to solve the problems existing in the prior art.

[0008] To achieve the above objectives, the present invention provides the following technical solution: A bactericidal composition, wherein the active ingredient of the bactericidal composition is a compound of trifluopyridine and fluopyram, or a compound of fluopyram and fluopyram.

[0009] Furthermore, the mass ratio of trifluoropyridine to fluopyram is 1:9.

[0010] Furthermore, the mass ratio of fluopyram to fluopyram is 1-8:9-2.

[0011] The present invention also provides the application of the pesticide composition in the prevention and control of crop diseases.

[0012] Furthermore, the crop disease is caused by infection with Rhizoctonia graminearum.

[0013] Compared with the prior art, the present invention has the following beneficial effects: This invention combines trifluopyridine or fluopyram with fluopyram. Indoor bioactivity tests revealed that the combination, within a certain mass ratio range, has a synergistic effect on Rhizoctonia graminearum, which causes wheat sheath blight. This helps improve the control effect of wheat sheath blight and is of great significance for the research and development of highly effective agents for the control of wheat sheath blight. Detailed Implementation

[0014] The technical solution of this invention patent will be clearly and completely described below. Obviously, the described embodiments are only some, not all, of the embodiments of this invention. Based on the embodiments of this invention, all other embodiments obtained by those skilled in the art without inventive effort are within the scope of protection of this invention.

[0015] Example: Indoor Activity Test 1. Test strains Rhizoctonia granatum ( Rhizoctonia cereale (), isolated from wheat sheath blight pathogens in Xinxiang City, Henan Province, and has been preserved in the laboratory to this day.

[0016] 2. Test reagents 86% triflupyridine technical grade, 96% fluopyram technical grade, and 98% fluopyram technical grade.

[0017] After the test reagent is dissolved, it is diluted with 0.1% Tween-80 aqueous solution to form a single-agent stock solution. Multiple ratios are set up, and each single-agent stock solution and ratio mixture is then diluted with 0.1% Tween-80 aqueous solution to form 5 mass concentration gradients.

[0018] 3. Test Methods Add 27 mL of pre-melted PDA medium and 3 mL of drug solution to a sterile conical flask, shake well, and pour the mixture into three 9 cm diameter petri dishes to prepare drug-containing plates of the corresponding concentrations. Each drug solution concentration is replicated three times, with three plates per replicate. A 0.1% Tween-80 aqueous solution is used as a blank control.

[0019] After the tested strains were propagated on PDA culture media, 5 mm diameter mycelial discs were cut from the edge of the colonies using a punch. These discs were then inoculated into the center of both the drug-containing and blank control plates, one disc per plate. The plates were then capped and incubated at 25°C. When the diameter of the blank control colonies reached approximately 2 / 3 of the plate's diameter, the colony diameter was measured using the cross-sectional method, and the inhibition rate of mycelial growth by different treatments was calculated.

[0020]

[0021] 4. Data Analysis Linear regression was performed with the logarithm of the fungicide concentration as x and the corresponding probability of mycelial growth inhibition as y to derive the virulence regression equation and the EC50 of the fungicide against the target pathogen. 50 The value was calculated, and the cotoxicity coefficient (CTC) was calculated according to Sun Yunpei's method.

[0022] 5. Measurement Results The synergistic effect of the drug was evaluated based on the calculated co-toxicity coefficient (CTC). CTC ≤ 80 indicates antagonistic effect, 80 < CTC < 120 indicates additive effect, and CTC ≥ 120 indicates synergistic effect. The results are shown in Table 1-2.

[0023] Table 1. Bioactivity test of trifluopyridine and fluopyram combined with Rhizoctonia graminearum As shown in Table 1, when trifluopyridine and fluopyram are combined in a mass ratio of 1:9, the co-toxicity coefficient of the combination against Rhizoctonia graminearum is greater than 120, showing a synergistic effect and improving the control effect against Rhizoctonia graminearum diseases.

[0024] Table 2. Bioactivity test of fluopyram and fluopyram combination against Rhizoctonia graminearum As shown in Table 2, when fluopyram and fluopyram are combined in a mass ratio of 1-8:9-2, the co-toxicity coefficient of the combination against Rhizoctonia graminearum is greater than 120, showing a synergistic effect and improving the control effect against Rhizoctonia graminearum diseases.

[0025] In summary, this invention combines trifluopyridine or fluopyram with fluopyram. Indoor bioactivity tests revealed that this combination, within a certain mass ratio range, has a synergistic effect against Rhizoctonia graminearum, which causes wheat sheath blight. This helps improve the control effect against wheat sheath blight and is of great significance for the research and development of highly effective agents for controlling wheat sheath blight.

Claims

1. A bactericidal composition, characterized in that, The active ingredient of the bactericidal composition is a compound of trifluoropyridine and fluopyram, or a compound of fluopyram and fluopyram.

2. The pesticide composition according to claim 1, characterized in that, The mass ratio of trifluoropyridine to fluopyram is 1:

9.

3. The pesticide composition according to claim 1, characterized in that, The mass ratio of fluopyram to fluopyram is 1-8:9-2.

4. The application of the pesticide composition according to claim 1 in the prevention and control of crop diseases.

5. The application according to claim 4, characterized in that, The crop disease is caused by infection with Rhizoctonia graminearum.

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