An in-built flexible temperature measurement system for monitoring body temperature of a human

Abstract

This invention discloses an embedded flexible temperature measurement system for monitoring human body temperature, including an in vivo temperature measurement system and a terminal. The in vivo temperature measurement system is implanted in the human body and includes a temperature acquisition module, a battery module, a communication module, and a micro-energy harvesting module. The battery provides electrical energy, the micro-energy harvesting module detects the remaining power of the battery module, and the output terminals of the micro-energy harvesting module and the temperature acquisition module are connected to the terminal via the communication module. This system can avoid frequent surgery to replace the battery.

Description

Technical Field

[0001] This invention belongs to the field of body temperature detection technology and relates to a built-in flexible temperature measurement system for monitoring human body temperature. Background Technology

[0002] Body temperature is one of the vital signs of the human body. Fever is a symptom of many diseases, including influenza, influenza, and postoperative infections. Timely monitoring of body temperature helps prevent illness and postoperative infections. Traditional body temperature monitoring technologies, such as mercury thermometers, are lengthy and complex, and cannot monitor body temperature in real time. Electronic temperature measuring instruments require wired charging and rely on physical cables, which have limitations such as interface wear, inconvenient storage, and fixed charging locations. Given the significant delay in detecting fever caused by infection after open surgery using conventional external body temperature monitoring methods, implantable body temperature monitoring systems can detect abnormalities promptly, allowing for timely treatment and saving patients' lives, which is of great importance. Implantable temperature measurement systems can be battery-powered, eliminating the limitations of wired charging, but frequent surgeries are needed to replace batteries to maintain system operation, increasing the surgical and economic risks for patients. Summary of the Invention

[0003] The purpose of this invention is to overcome the shortcomings of the prior art and provide a built-in flexible temperature measurement system for monitoring human body temperature, which can avoid frequent surgery and battery replacement.

[0004] To achieve the above objectives, this invention discloses an embedded flexible temperature measurement system for monitoring human body temperature, comprising an in vivo temperature measurement system and a terminal. The in vivo temperature measurement system is implanted in the human body and includes a temperature acquisition module, a communication module, a micro-energy harvesting module, and a power supply module for providing electrical energy. The micro-energy harvesting module detects the remaining power of the power supply module, and the output terminals of the micro-energy harvesting module and the temperature acquisition module are connected to the terminal via the communication module.

[0005] Furthermore, the power module includes a battery and an RF power supply, and the micro-energy harvesting module uses the RF power supply to receive external RF energy to charge the battery. Furthermore, the temperature acquisition module includes a cross-shaped sensor, a Wheatstone bridge, and a differential amplifier. The output of the cross-shaped sensor is connected to the input of the differential amplifier via the Wheatstone bridge, and the output of the differential amplifier is connected to the input of the communication module.

[0006] Furthermore, the micro-energy harvesting module includes a voltage doubler rectifier circuit and an energy harvesting circuit. The input terminal of the voltage doubler rectifier circuit is connected to the radio frequency power supply, the output terminal of the voltage doubler rectifier circuit is connected to the input terminal of the energy harvesting circuit, the energy harvesting circuit is connected to the battery, and the output terminal of the energy harvesting circuit is connected to the communication module.

[0007] Furthermore, the battery is a rechargeable button cell battery.

[0008] Furthermore, the communication module is a Bluetooth BLE SOC module.

[0009] Furthermore, the Bluetooth BLE SOC module includes a Bluetooth BLE SOC chip, a power supply circuit, and a BLE SOC control circuit. The power supply circuit includes a Boost converter and an LDO. The battery is connected to the input of the LDO, and the output of the LDO is connected to the BLE SOC control circuit to power it. The input of the Boost converter is connected to the battery, and the output of the Boost converter is connected to the temperature acquisition module to power it. The output of the BLE SOC control circuit is connected to the control terminal of the Boost converter and the Bluetooth BLE SOC chip. The input of the Bluetooth BLE SOC chip is connected to the outputs of the micro-energy harvesting module and the temperature acquisition module. The output of the Bluetooth BLE SOC chip is connected to the terminal.

[0010] Furthermore, the BLE SOC control circuit is connected to a timer.

[0011] Furthermore, using the timer, the BLE SOC control circuit is woken from sleep mode and put into normal mode at regular intervals. After executing the program, it enters sleep mode again, and the cycle repeats.

[0012] Furthermore, in normal mode, the BLE SOC control circuit controls the Boost circuit and the Bluetooth BLE SOC chip to work normally, providing power to the temperature acquisition module.

[0013] Furthermore, in sleep mode, the BLE SOC control circuit controls the Boost converter circuit and the Bluetooth BLE SOC chip to shut down, stopping power supply to the temperature acquisition module.

[0014] The present invention has the following beneficial effects: In practical operation, the built-in flexible temperature measurement system for monitoring human body temperature described in this invention uses a battery module for power supply. The output terminals of the micro-energy harvesting module and the temperature acquisition module are connected to a terminal via a communication module. The in vivo temperature measurement system is suitable for implantation in the human body to detect human body temperature and simultaneously detect the battery module's charge level. The human body temperature and battery module charge level are then transmitted to the terminal via the communication module to obtain the remaining battery charge in advance and avoid power outages. It should be noted that in actual operation, the battery module in this invention can be a wireless charging battery or a disposable battery, offering high flexibility.

[0015] Furthermore, by charging the battery with radio frequency power, real-time detection of human body temperature and battery power can be achieved, making it easier for nursing staff to detect abnormalities in body temperature and battery power in a timely manner, and to deal with abnormal body temperature in an early stage, so as to reduce the risk of worsening of the condition; when the system battery power is too low, it can be wirelessly charged to reduce the medical risks of frequent surgery and battery replacement. Attached Figure Description

[0016] To more clearly illustrate the technical solutions of the embodiments of this application, the drawings used in the description of the embodiments of this application will be briefly introduced below. Obviously, the drawings described below are only some embodiments of this application. For those skilled in the art, other drawings can be obtained based on these drawings without creative effort.

[0017] Figure 1 This is a schematic diagram of the present invention; Figure 2 This is a block diagram illustrating the principle of an in vivo temperature measurement system. Figure 3 This is a schematic diagram of the circuit board structure; Figure 4 This is a schematic diagram of the BLE SOC control circuit. Figure 5 This is a schematic diagram of the power supply circuit; Figure 6 This is the circuit diagram of the temperature acquisition module; Figure 7 This is a schematic diagram of the structure of the golden cross finger sensor; Figure 8 This is a schematic diagram of an energy harvesting circuit.

[0018] Among them, 1 is the circuit board, 11 is the antenna, 12 is the circuit module, 13 is the gold cross finger sensor connection pad, and 14 is the battery connection pad. Detailed Implementation

[0019] The technical solutions of the embodiments of the present invention will be clearly and completely described below with reference to the accompanying drawings. Obviously, the described embodiments are only some, not all, of the embodiments of the present invention. Based on the embodiments of the present invention, all other embodiments obtained by those skilled in the art without creative effort are within the scope of protection of the present invention.

[0020] In the description of this invention, it should be understood that the terms "comprising" and "including" indicate the presence of the described features, integrals, steps, operations, elements and / or components, but do not exclude the presence or addition of one or more other features, integrals, steps, operations, elements, components and / or collections thereof.

[0021] It should also be understood that the terminology used in this specification is for the purpose of describing particular embodiments only and is not intended to limit the invention. As used in this specification and the appended claims, the singular forms “a,” “an,” and “the” are intended to include the plural forms unless the context clearly indicates otherwise.

[0022] It should also be further understood that the term "and / or" as used in this specification and the appended claims refers to any combination and all possible combinations of one or more of the associated listed items, and includes such combinations. For example, A and / or B can represent three cases: A alone, A and B simultaneously, and B alone. Additionally, the character " / " in this invention generally indicates that the preceding and following objects have an "or" relationship.

[0023] It should be understood that although terms such as first, second, third, etc., may be used in the embodiments of the present invention to describe the preset range, these preset ranges should not be limited to these terms. These terms are only used to distinguish the preset ranges from one another. For example, without departing from the scope of the embodiments of the present invention, the first preset range may also be referred to as the second preset range, and similarly, the second preset range may also be referred to as the first preset range.

[0024] Depending on the context, the word "if" as used here can be interpreted as "when," "when," "in response to determination," or "in response to detection." Similarly, depending on the context, the phrase "if determination" or "if detection (of the stated condition or event)" can be interpreted as "when determination," "in response to determination," "when detection (of the stated condition or event)," or "in response to detection (of the stated condition or event)."

[0025] To make the objectives, technical solutions, and advantages of the embodiments of the present invention clearer, the technical solutions of the embodiments of the present invention will be clearly and completely described below with reference to the accompanying drawings. Obviously, the described embodiments are only some, not all, of the embodiments of the present invention. The components of the embodiments of the present invention described and shown in the accompanying drawings can generally be arranged and designed in various different configurations. Therefore, the following detailed description of the embodiments of the present invention provided in the accompanying drawings is not intended to limit the scope of the claimed invention, but merely to illustrate selected embodiments of the invention. All other embodiments obtained by those skilled in the art based on the embodiments of the present invention without inventive effort are within the scope of protection of the present invention.

[0026] The accompanying drawings illustrate various structural schematic diagrams according to embodiments disclosed in this invention. These drawings are not to scale, and some details have been enlarged for clarity, and some details may have been omitted. The shapes of the various regions and layers shown in the drawings, as well as their relative sizes and positional relationships, are merely exemplary and may deviate from reality due to manufacturing tolerances or technical limitations. Furthermore, those skilled in the art can design regions / layers with different shapes, sizes, and relative positions as needed.

[0027] Example 1 The built-in flexible temperature measurement system for monitoring human body temperature according to the present invention includes an in vivo temperature measurement system and a terminal. The in vivo temperature measurement system is implanted in the human body to detect the human body temperature, and the terminal is used to receive the body temperature information detected by the human body temperature measurement system and the status information of the in vivo temperature measurement system.

[0028] Specifically, the in vivo temperature measurement system includes a temperature acquisition module, a communication module, a micro-energy harvesting module, and a battery module. The battery module includes a radio frequency power supply and a battery. The battery provides electrical energy, and the micro-energy harvesting module detects the remaining battery power and receives external radio frequency energy to charge the battery. The output terminals of the micro-energy harvesting module and the temperature acquisition module are connected to the terminal via the communication module. Preferably, the communication module is a Bluetooth BLE SOC module, and the radio frequency power supply is an antenna.

[0029] In this embodiment, the temperature acquisition module includes a cross-shaped sensor, a Wheatstone bridge, and a differential amplifier. The output terminal of the cross-shaped sensor is connected to the input terminal of the differential amplifier via the Wheatstone bridge, and the output terminal of the differential amplifier is connected to the input terminal of the communication module.

[0030] During operation, the resistance of the interdigitated finger sensor has a linear relationship with temperature, making it suitable for attaching to human organs to detect body temperature. The interdigitated finger sensor is connected between the bridge arm resistor and ground in a Wheatstone bridge as the resistor to be measured. The Wheatstone bridge collects the resistance change of the interdigitated finger sensor and converts it into a voltage change. The input terminal of the differential amplifier is connected to the midpoint of the two bridge arms in the Wheatstone bridge to amplify the voltage change.

[0031] Specifically, the Wheatstone bridge accurately acquires the resistance change of the cross-finger sensor caused by a temperature change of 0.1℃, and converts it into a small voltage change. The differential amplifier amplifies the small voltage change to the minimum voltage value that can be acquired by the ADC built into the Bluetooth BLE SOC chip. The Bluetooth BLE SOC chip obtains the accurate human body temperature based on the detected organ temperature and organ temperature compensation, and sends the human body temperature to the terminal.

[0032] In this embodiment, the micro-energy harvesting module includes a voltage doubler rectifier circuit, an energy harvesting circuit, and an antenna. The input terminal of the voltage doubler rectifier circuit is connected to the antenna, the output terminal of the voltage doubler rectifier circuit is connected to the input terminal of the energy harvesting circuit, the energy harvesting circuit is connected to a battery (a rechargeable button cell battery), and the output terminal of the energy harvesting circuit is connected to a communication module.

[0033] During operation, the voltage doubler rectifier circuit receives the radio frequency energy received by the antenna, rectifies and boosts it into DC voltage, and charges the battery through the energy harvesting circuit. At the same time, the energy harvesting circuit detects the remaining battery power information and sends it to the terminal through the communication module.

[0034] Specifically, the ADC2 pin of the Bluetooth BLE SOC module is connected to the VBAT_OK pin of the energy harvesting circuit; the VCC pin of the power supply circuit of the Bluetooth BLE SOC module is connected to the VSTOR pin of the energy harvesting circuit; the antenna receives the radio frequency energy from the radio frequency power supply and converts it into high-frequency AC power; the voltage doubler rectifier circuit rectifies and boosts the high-frequency AC power to provide DC voltage for the energy harvesting circuit; the energy harvesting circuit collects DC voltage energy and supplies power to the battery and power supply circuit, while VBAT_OK detects the battery voltage; the ADC2 pin of the Bluetooth BLE SOC chip acquires the VBAT_OK voltage, and since there is a certain relationship between battery power and voltage, the battery power is obtained after processing and sent to the terminal.

[0035] In this embodiment, the Bluetooth BLE SOC module includes a Bluetooth BLE SOC chip, a power supply circuit, and a BLE SOC control circuit. The power supply circuit includes a Boost converter and an LDO. The battery is connected to the input of the LDO, and the output of the LDO is connected to the BLE SOC control circuit to power it. The input of the Boost converter is connected to the battery, and the output of the Boost converter is connected to the temperature acquisition module to power it. The output of the BLE SOC control circuit is connected to the control terminal of the Boost converter and the Bluetooth BLE SOC chip. The BLE SOC control circuit is equipped with a timer that periodically wakes the BLE SOC control circuit from sleep mode to normal mode, executes the program, and then returns to sleep mode, repeating the cycle.

[0036] The input terminal of the Bluetooth BLE SOC chip is connected to the output terminal of the micro-energy harvesting module and the temperature acquisition module, and the output terminal of the Bluetooth BLE SOC chip is connected to the terminal.

[0037] During operation, in normal mode, the BLE SOC control circuit controls the Boost circuit and Bluetooth BLE SOC chip to work normally, providing power to the temperature acquisition module; in sleep mode, the BLE SOC control circuit controls the Boost circuit and Bluetooth BLE SOC chip to shut down, stopping the power supply to the temperature acquisition module, thus stopping the human body temperature and battery power detection functions as well as the Bluetooth communication function.

[0038] For details, please refer to Figure 4 When the body temperature measurement system is in normal mode, the BLE SOC control circuit controls the IO port (EN pin of the Bluetooth BLE SOC) to output a high level to enable the boost function of the boost circuit, thus powering the temperature acquisition module and the micro-energy harvesting module. The ADC1 pin of the Bluetooth BLE SOC chip is connected to the output of the temperature acquisition circuit to acquire the body temperature, and the ADC2 pin of the Bluetooth BLE SOC chip is connected to the VBAT_OK pin of the micro-energy harvesting circuit to acquire the battery level. The Bluetooth BLE SOC chip performs digital-to-analog conversion and processing on the acquired data, and transmits radio frequency communication signals to the terminal through the radio frequency pin (RF pin of the Bluetooth BLE SOC). When in sleep mode, the BLE SOC control circuit sets the control IO port (EN pin of Bluetooth BLE SOC) to a low level, shutting off the power supply to the temperature acquisition module and the micro-energy harvesting module, stopping the human body temperature and battery power detection functions, as well as the Bluetooth communication function.

[0039] In sleep mode, the Bluetooth BLE SOC module's Bluetooth communication, I / O port control, and functions for collecting human body temperature and battery power are all turned off. It is woken up by a timer after a certain period of time (e.g., 30 seconds) and returned to normal mode. The system remains in sleep mode for a long time and only enters normal mode when it is woken up. Data transmission requires a Bluetooth connection with a terminal (such as a mobile phone). Then, the terminal scans the broadcast data of the body temperature measurement system to obtain human body temperature and battery power in real time.

[0040] In this embodiment, the terminal can be a mobile phone or a computer, etc. It receives the remaining power information sent by the micro-energy collection and display module and the temperature information sent by the temperature acquisition module, and issues an alarm when the body temperature and battery power are abnormal.

[0041] In this embodiment, the radio frequency power supply is used to wirelessly charge the internal battery when the battery power is too low, realizing real-time monitoring of human body temperature and system battery power, which makes it easier for nursing staff to quickly detect abnormal body temperature and prevent danger in time. In addition, the use of microwave wireless charging to charge the internal temperature measurement system reduces the surgical and economic risks caused by frequent surgery and battery replacement.

[0042] In this embodiment, the in vivo temperature measurement system needs to be implanted in the human body. Therefore, the battery and circuit board are sealed with a mixture of medical low-modulus silicone and polyolefin. The sealing body leads out the gold cross finger sensor connection line to connect the gold cross finger sensor.

[0043] In this embodiment, the terminal determines whether the human body is overheating and whether the battery is depleted based on the received human body temperature and battery level, and displays the human body temperature and battery level in real time. When it is determined that the human body is overheating or the battery level is too low, an alarm is triggered.

[0044] In this embodiment, the radio frequency power supply outputs radio frequency energy that meets the charging power of the system battery according to the low battery alarm, and wirelessly charges the battery of the in vivo temperature measurement system. The wireless charging frequency is in the 2.4 GHz band.

[0045] Example 2 The internal temperature measurement system is implanted in the open area of ​​the kidney surgical site. The gold interdigital sensor is surgically attached to the kidney injury site. The internal temperature measurement system detects the temperature at the kidney injury site and compensates for it by comparing it with the body's core temperature to obtain an accurate body temperature. This temperature is then sent to a terminal (such as a mobile phone or computer held by the user, caregiver, monitor, or medical staff) at regular intervals. The terminal receives the body temperature data from the internal temperature measurement system and judges the body temperature according to the judgment criteria. If the body temperature is abnormal, an alarm is triggered.

[0046] Example 3 When the terminal determines that the battery power is too low based on the judgment conditions, the radio frequency power supply amplifies the 2.4GHz band radio frequency signal to the minimum power level that meets the system battery charging and system operation requirements. The emitted electromagnetic waves are transmitted through the air to the receiving antenna of the body temperature measurement system, which operates at a frequency of 2.4GHz. The receiving antenna receives energy and supplies power to the battery and power supply circuit through the micro energy harvesting module.

[0047] In summary, the in vivo temperature measurement system of this invention is suitable for implantation in the human body to detect body temperature and battery power, and transmits the body temperature and battery power to a terminal. The terminal is suitable for receiving the body temperature and battery power transmitted by the in vivo temperature measurement system, and triggering an alarm when the body temperature or battery power is abnormal. When the radio frequency power supply battery is too low, it wirelessly charges the battery of the in vivo temperature measurement system, realizing real-time detection of body temperature and battery power. This facilitates timely detection of abnormal body temperature and battery power by nursing staff, enabling early intervention for abnormal body temperature and reducing the risk of disease progression. Wireless charging of the system battery when it is too low reduces the medical risks associated with frequent surgical battery replacements.

[0048] Other embodiments of the invention will readily occur to those skilled in the art upon consideration of the specification and disclosure of the invention. This application is intended to cover any variations, uses, or adaptations of the invention that follow the general principles of the invention and include common knowledge or customary techniques in the art not disclosed herein. The specification and examples are to be considered exemplary only, and the true scope and spirit of the invention are indicated by the following claims.

[0049] It should be understood that the present invention is not limited to the precise structure described above and shown in the accompanying drawings, and various modifications and changes can be made without departing from its scope. The scope of the invention is limited only by the appended claims.

[0050] The above description is merely a preferred embodiment of the present invention and does not constitute any limitation on the present invention. Any simple modifications, alterations, or equivalent structural changes made to the above embodiments based on the technical essence of the present invention shall still fall within the protection scope of the present invention.

Claims

1. A built-in flexible temperature measurement system for monitoring human body temperature, characterized in that, The invention includes an in vivo temperature measurement system and a terminal. The in vivo temperature measurement system is implanted in the human body and includes a temperature acquisition module, a communication module, a micro-energy harvesting module, and a power supply module for providing electrical energy. The micro-energy harvesting module detects the remaining power of the power supply module. The output terminals of the micro-energy harvesting module and the temperature acquisition module are connected to the terminal via the communication module.

2. The built-in flexible temperature measurement system for monitoring human body temperature according to claim 1, characterized in that, The power module includes a battery and an RF power supply. The micro-energy harvesting module uses the RF power supply to receive external RF energy to charge the battery. The temperature acquisition module includes a gold interdigitation sensor, a Wheatstone bridge, and a differential amplifier. The output of the gold interdigitation sensor is connected to the input of the differential amplifier via the Wheatstone bridge, and the output of the differential amplifier is connected to the input of the communication module.

3. The built-in flexible temperature measurement system for monitoring human body temperature according to claim 2, characterized in that, The micro-energy harvesting module includes a voltage doubler rectifier circuit and an energy harvesting circuit. The input terminal of the voltage doubler rectifier circuit is connected to the radio frequency power supply, the output terminal of the voltage doubler rectifier circuit is connected to the input terminal of the energy harvesting circuit, the energy harvesting circuit is connected to the battery, and the output terminal of the energy harvesting circuit is connected to the communication module.

4. The built-in flexible temperature measurement system for monitoring human body temperature according to claim 2, characterized in that, The battery is a rechargeable button cell battery.

5. The built-in flexible temperature measurement system for monitoring human body temperature according to claim 2, characterized in that, The communication module is a Bluetooth BLE SOC module.

6. The built-in flexible temperature measurement system for monitoring human body temperature according to claim 5, characterized in that, The Bluetooth BLE SOC module includes a Bluetooth BLE SOC chip, a power supply circuit, and a BLE SOC control circuit. The power supply circuit includes a Boost converter and an LDO. The battery is connected to the input of the LDO, and the output of the LDO is connected to the BLE SOC control circuit to power it. The input of the Boost converter is connected to the battery, and its output is connected to the temperature acquisition module to power it. The output of the BLE SOC control circuit is connected to the control terminal of the Boost converter and the Bluetooth BLE SOC chip. The input of the Bluetooth BLE SOC chip is connected to the outputs of the micro-energy harvesting module and the temperature acquisition module. The output of the Bluetooth BLE SOC chip is connected to the terminal.

7. The built-in flexible temperature measurement system for monitoring human body temperature according to claim 6, characterized in that, The BLE SOC control circuit is connected to a timer.

8. The built-in flexible temperature measurement system for monitoring human body temperature according to claim 7, characterized in that, Using the timer, the BLE SOC control circuit is woken from sleep mode at regular intervals to enter normal mode. After executing the program, it enters sleep mode again, and the cycle repeats.

9. The built-in flexible temperature measurement system for monitoring human body temperature according to claim 8, characterized in that, In normal mode, the BLE SOC control circuit controls the Boost circuit and the Bluetooth BLE SOC chip to work normally, providing power to the temperature acquisition module.

10. The built-in flexible temperature measurement system for monitoring human body temperature according to claim 8, characterized in that, In sleep mode, the BLE SOC control circuit shuts down the Boost converter circuit and the Bluetooth BLE SOC chip, stopping power supply to the temperature acquisition module.

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