Vascular covered stent

Abstract

The present application provides a kind of vascular covered stent, including stent body, stent body is covered with covering, the covering is equipped with opening area, the opening area is provided with multiple micropores, the micropore is used to make fluid from the inside of the vascular covered stent to outside, the covering is provided with mark for positioning on both ends of the opening area along its axial direction.The vascular covered stent can also be arranged by mark point, so that it can quickly move the opening area to the communication between aorta and branch artery when placed, facilitate intuitive control the orientation and range of opening area, reduce adjustment time, the overall operation time is reduced to 45-65 minutes from 120-200 minutes, greatly save the overall operation time.

Description

Technical Field

[0001] This invention relates to the field of medical device technology, specifically to a vascular covered stent. Background Technology

[0002] A vascular stent graft is an implantable device that covers a metal stent with a biocompatible membrane. Its core function is to isolate the diseased segment of the blood vessel through the membrane, reconstruct the blood flow channel, and prevent blood leakage. However, when the lesion involves important branch arteries, traditional vascular stent grafts can completely block blood flow to the branch, leading to organ ischemia. Therefore, precisely creating micropores in the graft area corresponding to the branch artery has become a key innovation. These micropores allow blood to perfuse the branch vessel in a controlled manner, maintaining the isolation and sealing of the main vessel while ensuring blood supply to the branch organ.

[0003] For example, Chinese utility model patent with publication number CN223614976U provides a covered stent. This covered stent, by reasonably arranging the diameter and density of the micropores, can ensure that the blood flow in the branch artery is laminar, avoiding turbulent blood flow that could lead to branch artery thrombosis, which would increase the probability of arteriosclerosis, arterial stenosis, and cerebral infarction. It can also prevent turbulent flow from causing aortic dissection that cannot be healed, reduce the blood flow pressure in the branch artery, ensure the blood flow and perfusion volume of the branch artery, and thus ensure the patency of the branch artery.

[0004] However, existing microporous covered stents do not allow for direct visualization of the specific location and orientation of the opening area during placement, which can easily lead to improper placement of the stent in the opening area during surgery, requiring a significant amount of time to adjust the stent's position. Therefore, a vascular covered stent is proposed to solve the above problems. Summary of the Invention

[0005] Therefore, it is necessary to provide a vascular covered stent to address the problem that the specific location and orientation of the opening area of ​​existing microporous vascular covered stents cannot be directly known during placement, which easily leads to the stent not being placed in the correct position during surgery, thus requiring a lot of time to adjust the stent's position.

[0006] To achieve the above objectives, the present invention provides the following technical solution: a vascular covered stent, comprising: The support body; and A membrane is applied to the stent body. The membrane has an opening area with multiple micropores, which allow fluid to flow from the inside of the vascular covered stent to the outside. The film has positioning marks at both ends of the opening area along its axial direction.

[0007] In one embodiment, the diameter of the micropores is 1.5-1.8 mm, the density of the micropores is 25-36 per 2 square centimeters, the angle range of the opening area in the circumferential direction of the vascular stent is 45°-360°, and the length of the opening area along the axial direction of the vascular stent is no more than 12 cm.

[0008] In one embodiment, the angle range of the opening area in the circumferential direction of the vascular stent is 45°-180°.

[0009] In one embodiment, the vascular stent graft has a proximal end and a distal end, with the opening region located at the proximal end of the vascular stent graft.

[0010] In one embodiment, the distance between the opening area and the proximal end face of the vascular stent is 1.5-8 cm.

[0011] In one embodiment, the length of the opening area along the axial direction of the vascular stent is 3-8 cm.

[0012] In one embodiment, the micropores are arranged in an array in the opening region.

[0013] In one embodiment, the micropore includes at least one of a circular hole, an elliptical hole, or a polygonal hole.

[0014] In one embodiment, a set of marks is provided at the centerline of the proximal end near the opening area, and two sets of marks are provided at the proximal end away from the opening area. The two sets of marks are respectively aligned with the two ends of the opening area in the radial direction of the film. A set of marks is provided at the centerline of the distal end near the opening area.

[0015] In one embodiment, three sets of marks are provided at the proximal end and the distal end near the opening region, wherein two sets of marks are aligned with the two ends of the opening region in the radial direction of the coating, and the other set of marks is located at the centerline of the opening region. In one embodiment, the support body is provided with a fixing part at the proximal end.

[0016] In one embodiment, multiple sets of fixing parts are provided and arranged in a circumferential manner at one end of the bracket body, and connected to the curved part of the bracket body near the proximal end.

[0017] In one embodiment, the fixing part is a barb.

[0018] In one embodiment, the length of the barb is 1.2mm to 1.8mm.

[0019] In one embodiment, the proximal end of the membrane covers an area that extends beyond the area of ​​the stent body.

[0020] Compared with the prior art, the present invention has at least the following advantages: This vascular stent graft, through the placement of micropores, ensures laminar blood flow within the branch arteries, preventing turbulent flow that could lead to branch artery thrombosis, increased risk of arteriosclerosis and stenosis, and increased stroke risk. It also prevents aortic dissection from failing to heal due to turbulent flow. Simultaneously, by rationally arranging the diameter and density of the micropores, it reduces blood flow pressure in the branch arteries, ensuring blood flow and perfusion, thereby guaranteeing branch artery patency. This vascular stent graft can be placed at the anterior end of the aorta, including the very anterior portion. Existing perforated stents require fenestration and alignment with the very anterior branch artery. Furthermore, the placement of marker points allows for rapid movement of the perforation area to the junction of the aorta and branch arteries during placement, facilitating intuitive control of the perforation area's orientation and extent, reducing adjustment time, and decreasing the overall surgical time from 120-200 minutes to 45-65 minutes, significantly saving overall surgical time. Attached Figure Description

[0021] To more clearly illustrate the specific embodiments of the present invention, the accompanying drawings used in the specific embodiments will be briefly described below. In all the drawings, the elements or parts are not necessarily drawn to scale.

[0022] Figure 1 A three-dimensional structural schematic diagram of a vascular covered stent provided by the present invention; Figure 2 A schematic diagram of one embodiment of a vascular covered stent provided by the present invention; Figure 3 This is a schematic diagram of another embodiment of a vascular covered stent provided by the present invention; Figure 4 This is a schematic diagram illustrating laminar blood flow within a branch artery. Figure 5 This is a schematic diagram illustrating turbulent blood flow within a branch artery. Figure 6 This is a schematic diagram showing that the interlayer has not healed. Figure 7 A comparison chart of postoperative blood flow in each branch; Figure 8 A graph for assessing the flow rate and velocity in branch vessels; Figure 9 A comparison diagram of pressure waveforms in the true and false chambers; Figure 10 A schematic diagram showing the blood flow and perfusion volume in the branch arteries before and after the implantation of a vascular stent graft. Figure 11 This is a schematic diagram of a vascular stent graft with a micropore diameter of 1.5 mm being installed inside a blood vessel. Figure 12 This is a schematic diagram of a vascular stent graft with a micropore diameter of 2.0 mm being installed inside a blood vessel. Figure 13 This is a schematic diagram showing that the pressure in the branch arteries is significantly lower than that in the aorta. Figure 14 This is a schematic diagram showing that after implantation of a vascular stent graft, the blood flow in the branch artery is laminar and relatively fast. Figure 15 A schematic diagram illustrating the effect of orifice shape on flow rate; Figure 16 An angiographic image after the placement of a vascular stent graft.

[0023] Figure label: 10. Scaffold body; 20. Covering; 201. Proximal end; 202. Distal end; 21. Opening area; 22. Micropore; 23. Marking; 24. Fixation part. Detailed Implementation

[0024] To make the above-mentioned objects, features, and advantages of the present invention more apparent and understandable, specific embodiments of the present invention will be described in detail below with reference to the accompanying drawings. Many specific details are set forth in the following description to provide a thorough understanding of the present invention. However, the present invention can be practiced in many other ways different from those described herein, and those skilled in the art can make similar modifications without departing from the spirit of the invention; therefore, the invention is not limited to the specific embodiments disclosed below.

[0025] It should be noted that when an element is referred to as being "fixed to" another element, it can be directly attached to the other element or there may be an intervening element. When an element is referred to as being "connected to" another element, it can be directly connected to the other element or there may be an intervening element. The terms "vertical," "horizontal," "left," "right," and similar expressions used herein are for illustrative purposes only and do not represent the only possible implementation.

[0026] Unless otherwise defined, all technical and scientific terms used herein have the same meaning as commonly understood by one of ordinary skill in the art to which this invention pertains. The terminology used herein in the description of the invention is for the purpose of describing particular embodiments only and is not intended to be limiting of the invention.

[0027] Example:

[0028] This embodiment discloses a vascular stent graft, mainly used in the clinical treatment of aortic aneurysms and aortic dissections. The standard applicable stent diameter range is 26-42 mm. Figure 1 As shown, the vascular covered stent consists of two parts: the stent body 10 and the covering 20. The stent body 10 serves as the load-bearing support structure for the vascular covered stent, while the covering 20 is entirely placed on the stent body 10. The covering 20 has a specially designed opening area 21, within which micropores 22 are evenly distributed. The micropores 22 act as channels for blood flow, allowing blood from inside the aorta to flow to the outside through the stent, ensuring normal blood perfusion to the branch arteries. Through hemodynamic experiments and clinical studies, the core basic parameters of the micropores were determined: the diameter of the micropores 22 is 1.5-1.8 mm, and the micropore density is 25-36 per 2 square centimeters.

[0029] The diameter of micropore 22 is an important parameter affecting the hemodynamic state of branch arteries. Combined with... Figures 4 to 6 Experimental research results show that the size of the micropore diameter directly determines the blood flow pattern: when the micropore diameter is ≥2mm, the blood flowing through the micropore into the branch artery is in a turbulent state, which significantly increases the incidence of branch artery thrombosis, arteriosclerosis, and arterial stenosis, increases the risk of stroke, and also leads to the inability of aortic dissection to heal properly; when the micropore diameter is 1.9mm, the blood flow in the branch artery exhibits an unstable state with both laminar and turbulent flow; when the micropore diameter is <1.9mm, the blood flow in the branch artery can maintain a stable laminar flow state, effectively reducing the probability of vascular lesions, ensuring sufficient blood flow velocity and cerebral perfusion level, and reducing the occurrence of stroke.

[0030] Based on experimental data, the minimum diameter of the micropores can be further defined: when the micropore diameter is <1.5mm, the pressure drop in the branch artery blood flow will exceed 50%, which can easily lead to cerebral ischemia and induce neurological deficits such as limb weakness, limb numbness, and slurred speech; if the pressure drop exceeds 70%, it will cause irreversible cerebral infarction. Simultaneously, excessively small micropores will be slowly covered by vascular endothelial tissue, leading to micropore occlusion and further inducing cerebral infarction. However, when the micropore diameter is controlled within the range of 1.5-1.8mm, there can be no significant difference in perfusion volume between the branch arteries before and after surgery, ensuring stable and safe blood flow perfusion. Therefore, this protocol sets the lower limit of the diameter of micropore 22 to 1.5mm.

[0031] Besides diameter, micropore density also has a crucial impact on branch arterial blood flow pressure and the stability of the diaphragm structure. (Combined) Figure 10According to the experimental results in Table 1 (see below), under the premise of fixed micropore diameter, when 4, 9, 16 and 25 micropores were arranged in each 2 square centimeter area, the blood flow pressure of the branch artery decreased by about 12.5%, 16%, 20% and 23% respectively; when the number of micropores per 2 square centimeters exceeded 25, the blood flow pressure of the branch artery gradually tended to stabilize.

[0032] However, there is an upper limit to the micropore density. When the number of micropores exceeds 36 per 2 square centimeters, the spacing between micropores becomes too small, which can lead to stress concentration at the pore edges and stress superposition of the coating material between pores. Under continuous blood flow pressure, the coating is prone to tearing and disintegration, causing blood to flow into the branch arteries in a turbulent manner, which can induce thrombosis, arteriosclerosis, arterial stenosis and cerebral infarction, while also hindering the healing of aortic dissection.

[0033] Based on a comprehensive evaluation of multiple indicators, including branch artery blood flow pattern, blood flow pressure, perfusion flow rate, cerebral blood supply safety, and the stability of the diaphragm structure, this scheme ultimately determined the optimal basic parameter range for the micropores: micropore diameter 1.5-1.8 mm, and micropore density 25-36 per 2 square centimeters.

[0034] Combination Figures 4 to 16 The experimental results demonstrate that, after implantation into the human body, the vascular stent graft with the above parameters effectively increases the blood flow velocity in the three branches of the aorta, maintains stable laminar flow throughout, and ensures uniform pressure distribution in the aorta and branch arteries, with branch artery pressure remaining within a reasonable range of reduction. Simultaneously, the micropore diameter and density parameters work synergistically to precisely match the elastic modulus of the vessel wall, reducing local stress concentration. This not only efficiently repairs aortic dissection tears but also reduces blood flow resistance, resulting in a significantly better overall treatment effect than existing conventional stenting methods. Figures 7 to 9 As shown, the postoperative flow rates of all covered branch arteries were within the normal range, as were the peak and average flow velocities of all covered branch arteries, and the total flow rates of all covered branch arteries and the branches above the aortic arch. The postoperative false lumen pressure was significantly lower than that before the operation.

[0035] Within the basic parameter range, specific values ​​can be flexibly selected according to clinical needs: the diameter of micropore 22 can be selected from any value within the range of 1.5mm, 1.6mm, 1.7mm, and 1.8mm; the density of micropore 22 can be selected from any integer within the range of 25-36 per 2 square centimeters (25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, and 36).

[0036] To further enhance clinical safety and structural stability, this design sets a more refined parameter range: micropore diameter of 1.6-1.7 mm and micropore density of 25-30 per 2 square centimeters. Experiments show that a 1.5 mm diameter micropore results in a nearly 50% reduction in branch arterial blood flow pressure, still posing a risk of mild cerebral ischemia and neurological deficits. Therefore, a diameter greater than 1.5 mm is preferred. Simultaneously, a blood flow pressure stabilization is achieved with 25 micropores per 2 square centimeters. Using a low-density range of 25-30 micropores effectively increases the micropore spacing, avoiding stress concentration and stress superposition, and fundamentally preventing membrane tearing and disintegration. The optimal design parameters in this embodiment are: micropore diameter of 1.6 mm and micropore density of 25 per 2 square centimeters.

[0037] Regarding the overall stent specifications, this covered stent is compatible with mainstream clinical vessel sizes, with parameters ranging from 12-24cm in length, 26-46mm in diameter, and 0-12mm in taper. Specifically, stent lengths can be selected from 12.0cm, 14cm, 15cm, 16.0cm, 17.0cm, 18.0cm, 19.0cm, 20.0cm, 21.0cm, 22.0cm, and 24cm; proximal and distal diameters can be selected from 26mm, 28mm, 30mm, 32mm, 34mm, 36mm, 38mm, 40mm, 42mm, 44mm, and 46mm; and stent tapers can be selected from 0, 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, and 12mm.

[0038] like Figures 1 to 3 As shown, the vascular stent graft is divided into a proximal end 201 and a distal end 202 along the axial direction. The end closer to the heart is the proximal end 201, and the end farther from the heart is the distal end 202. In this design, the opening area 21 is concentrated at the proximal end 201 of the stent, adapting to the anatomical location of the aortic branch arteries. In some preferred embodiments, the lining 20 of the proximal end 201 protrudes beyond the stent body 10, completely covering the end of the stent body 10, thereby reducing stress on the proximal end 201 of the vascular stent graft, minimizing damage to the blood vessel, and reducing the risk of rupture.

[0039] Regarding the axial dimension design of the opening area, the maximum length of the opening area 21 along the stent axis (parallel to the stent axis and conforming to the direction of vascular extension) is limited to 12cm. Based on clinical vascular anatomy data, the maximum length of branch arteries in normal individuals and patients with aortic dilatation disease is 86mm, and the minimum length is 19mm. This dimensional limit is then determined by considering the necessary 25mm anchorage zone requirement for the stent. To accommodate the vascular structure of most patients, an axial length of 3-8cm for the opening area is preferred, with values ​​of 3cm, 4cm, 5cm, 6cm, 7cm, 8cm, and any value within this range possible.

[0040] Meanwhile, the distance between the opening area 21 and the proximal end face of the stent 201 is set to 1.5-8cm to precisely define the axial installation position of the opening area. This distance can be flexibly adjusted according to the actual distribution of branch arteries in different patients. The preferred distance includes 1.5cm, 2cm, 3cm, 4cm, 5cm, 6cm, 7cm, 8cm, and any value within the range. By measuring the length of the three branches of the thoracic aorta in 568 patients, the minimum was 1.8cm and the maximum was 7.6cm. The distance between the opening area 21 and the proximal end face of the stent 201 was adjusted from the original 3-8cm to 1.5-8cm, which can fully cover the needs of all patients.

[0041] Regarding the design of the circumferential angle of the opening area, the original adjustable range of the coverage angle of the opening area 21 in the circumferential direction of the vascular stent graft is 45°-360°. During stent delivery, uncontrollable spontaneous rotation can occur. A 360° full circumferential opening can completely avoid the risk of misalignment and blockage between the micropores and branch arteries, but it can cause graft leakage, leading to blood seepage into the dissection and delaying healing. Therefore, this design optimizes the angle range to 45°-180°, which can effectively reduce graft leakage and shorten the dissection healing period by approximately 3 months. Precise alignment of the micropores and branch arteries can be achieved through intraoperative stent fine-tuning. The preferred circumferential coverage angles are 45°, 60°, 90°, 120°, and 180°, with 180° minimizing the difficulty of intraoperative positioning.

[0042] In terms of the shape design of the opening area, in this embodiment, the opening area 21 unfolds into a rectangular structure, with two adjacent sides extending along the circumference and axial direction of the support, respectively. In other embodiments, the opening area 21 can also be designed as a regular shape such as a triangle, quadrilateral, pentagon, or hexagon, or various irregular shapes, depending on actual processing and clinical needs.

[0043] The micro-hole 22 can adopt at least one structure, such as a circular hole or a polygonal hole. The polygonal hole can be a triangular hole, a rhomboid hole, a hexagonal hole, etc. To simplify the processing technology and ensure the accuracy of the opening size, this solution preferably adopts a circular hole for all micro-holes.

[0044] like Figure 15 As shown, to verify the impact of micropore shape on treatment efficacy, this method utilizes real human vascular data and COMSOL simulation software to construct three simulation models, including the true lumen of the aortic arch and branches of the lenticulostriate arteries (LSA), corresponding to circular, rhomboid, and hexagonal pore structures, respectively. By simulating real blood inlet velocity and outlet pressure, five consecutive blood flow cycles (approximately 5 seconds) were calculated, and the average flow rate at the lenticulostriate artery outlet was statistically analyzed. Simulation results show that, under the premise of essentially consistent porosity, the micropore shape has no significant impact on the perfusion flow rate of the branch arteries.

[0045] Regarding the arrangement of micropores, this scheme preferably arranges the micropores 22 in an array uniformly within the opening area 21. This ensures that the spacing between each micropore is uniform, achieving stable output of blood flow and perfusion volume in the branch arteries, while also ensuring uniform stress on the membrane and structural stability. In other optional embodiments, the micropores can also be arranged in a non-array uniform manner or with artificially uniform openings.

[0046] To systematically verify the clinical application efficacy of the vascular covered stent of this application, simulation control experiments were conducted below using multiple sets of examples and comparative examples. The following examples are only used to illustrate the technical solution of this application and are not intended to limit the scope of protection of this application.

[0047] Examples 1-33 and Comparative Examples 1-17 of this experiment adopted the same specifications and installation parameters for vascular covered stents: overall stent length 20cm, diameter 30mm, taper 4; the opening area is set at the proximal end of the stent, with an axial length of 5cm, and the distance between the opening area and the proximal end face is 4cm.

[0048] Based on the above unified parameters, a vascular covered stent simulation model was constructed to simulate the clinical scenario of stent implantation in the thoracic aorta, with the opening area covering the brachiocephalic trunk, carotid artery, and subclavian artery. The simulation test system was used to detect and record the branch artery blood flow characteristics, blood flow pressure, vascular patency rate, and aortic dissection healing status of each group of samples.

[0049] Table 1: Parameters and test results of Examples 1-33 and Comparative Examples 1-17:

[0050] Note: In Table 1 above, a branch artery patency rate of 95% or higher is considered acceptable, while a rate below 95% is considered unacceptable. A decrease in branch artery blood flow pressure exceeding 50% is unacceptable, while a decrease of no more than 50% is acceptable.

[0051] Please continue reading Figure 1-3 and Figure 14 To improve the accuracy of surgical implantation, both sides of the axial edge of the opening area 21 are provided with radiopaque positioning marks 23, preferably of O-type structure, which can be clearly visualized under X-ray. During the operation, the boundary of the opening area can be accurately defined, avoiding stent positioning deviation and ensuring the accurate installation position of the opening area.

[0052] In a preferred embodiment, a set of marks 23 is provided at the midline of the proximal end 201 near the perforation region 21, and two sets of marks 23 are provided at the position of the proximal end 201 away from the perforation region 21. The two sets of marks 23 are respectively aligned with the two ends of the perforation region 21 in the radial direction of the covering 20. A set of marks 23 is provided at the midline of the distal end 202 near the perforation region 21. When placing the vascular covered stent, the placement range of the perforation region 21 can be determined by the two sets of marks 23 closest to the proximal end 201, and the orientation of the perforation region 21 can be determined by the two sets of marks 23 located at the midline of the perforation region 21.

[0053] Understandably, in another preferred embodiment, three sets of marks 23 are provided at the proximal end 201 and the distal end 202 near the perforation area 21. Two sets of marks 23 are aligned with the two ends of the perforation area 21 in the radial direction of the covering film 20, respectively, and the other set of marks 23 is located at the centerline of the perforation area 21. By arranging six sets of marks 23, the placement range and orientation of the perforation area 21 can also be determined.

[0054] It is understood that in some other preferred embodiments, the support body 10 is provided with a fixing part 24 at the proximal end 201. Multiple sets of fixing parts 24 are provided and arranged in a circumferential manner at one end of the support body 10, and are connected to the curved part of the support body 10 near the proximal end 201. Preferably, the fixing part 24 is a barb with a barb length of 1.2mm to 1.8mm.

[0055] The barbed fixing part 24 increases the adhesion between the vascular stent and the vessel wall, reduces gaps between the stent and the vessel wall, and prevents blood from leaking out through these gaps, thus preventing endoleak. Existing vascular stents are mainly fixed to the vessel wall by the outward expansion force of the stent diameter being about 10% larger than the vessel diameter. Adding barbs allows the size of the vascular stent to be designed to match the size of the vessel wall. The barbs then insert into the vessel wall for fixation, which not only reduces the expansion pressure on the cardiovascular system but also makes the vascular stent more securely fixed.

[0056] like Figure 11 , 12 As shown, it can be understood that in some preferred embodiments, the vascular stent graft includes a large bend side and a small bend side after bending, with the length of the large bend side being greater than that of the small bend side. The lengths of the large bend side and the small bend side are πR (bending radius), where R is 14~23mm, the stent tip is 120~150mm, the stent diameter is 26~48mm, and the difference between the diameter of the large bend side and the diameter of the small bend side is πr (large bend side) - πr (small bend side). This design allows the micropores 22 of the vascular stent graft to bend and unfold after bending, avoiding micropore blockage.

[0057] Specific usage and beneficial effects of the present invention: The covered stent 20, through the arrangement of micropores 22, ensures laminar blood flow within the branch arteries, preventing turbulent flow that could lead to branch artery thrombosis, increased risk of arteriosclerosis and stenosis, and increased risk of stroke. It also prevents aortic dissection from failing to heal due to turbulent flow. Simultaneously, by rationally arranging the diameter and density of the micropores 22, the blood flow pressure in the branch arteries is reduced, ensuring blood flow and perfusion, thereby guaranteeing the patency of the branch arteries. The covered stent 20 can be placed at the anterior end of the aorta, including the very anterior portion. Existing perforated stents require fenestration and alignment with the very anterior branch artery. Furthermore, the covered stent 20, with its marked 23 points, allows for rapid movement of the perforation area 21 to the junction of the aorta and branch arteries during placement. This facilitates intuitive control of the orientation and extent of the perforation area 21, reducing adjustment time and decreasing the overall surgical time from 120-200 minutes to 45-65 minutes, significantly saving overall surgical time.

[0058] The above embodiments are only used to illustrate the technical solutions of the present invention, and are not intended to limit it. Although the present invention has been described in detail with reference to the foregoing embodiments, those skilled in the art should understand that modifications can still be made to the technical solutions described in the foregoing embodiments, or equivalent substitutions can be made to some or all of the technical features therein. Such modifications or substitutions do not cause the essence of the corresponding technical solutions to deviate from the scope of the technical solutions of the embodiments of the present invention, and they should all be covered within the scope of the claims and specification of the present invention.

Claims

1. A vascular covered stent, characterized in that, Including: The support body; and A membrane is applied to the stent body. The membrane has an opening area with multiple micropores, which allow fluid to flow from the inside of the vascular covered stent to the outside. The film has positioning marks at both ends of the opening area along its axial direction.

2. The vascular covered stent according to claim 1, characterized in that: The diameter of the micropores is 1.5-1.8 mm, and the density of the micropores is 25-36 per 2 square centimeters; the angle range of the opening area in the circumferential direction of the vascular stent is 45°-360°; the length of the opening area along the axial direction of the vascular stent is no more than 12 cm.

3. The vascular covered stent according to claim 1, characterized in that: The angle range of the opening area in the circumferential direction of the vascular covered stent is 45°-180°.

4. The vascular covered stent according to claim 1, characterized in that: The vascular stent graft has a proximal end and a distal end, and the opening area is located at the proximal end of the vascular stent graft.

5. A vascular covered stent according to claim 3, characterized in that: The distance between the opening area and the proximal end face of the vascular covered stent is 1.5-8cm.

6. A vascular covered stent according to claim 1, 4 or 5, characterized in that: The length of the opening area along the axial direction of the vascular covered stent is 3-8 cm.

7. A vascular covered stent according to claim 1, characterized in that: The micropores are arranged in an array in the opening area.

8. A vascular covered stent according to claim 1, characterized in that: The micropores include at least one of round holes, elliptical holes, or polygonal holes.

9. A vascular covered stent according to claim 4, characterized in that: A set of marks is provided at the proximal end near the centerline of the opening area, and two sets of marks are provided at the proximal end away from the opening area. The two sets of marks are respectively aligned with the two ends of the opening area in the radial direction of the film. A set of marks is provided at the distal end near the centerline of the opening area.

10. A vascular covered stent according to claim 4, characterized in that: Three sets of marks are provided at the proximal end and the distal end near the opening area, two sets of marks being aligned with the two ends of the opening area in the radial direction of the film, and the other set of marks being located at the centerline of the opening area.

11. A vascular covered stent according to claim 4, characterized in that: The support body has a fixing part located at the proximal end.

12. A vascular covered stent according to claim 11, characterized in that: Multiple sets of fixing parts are provided and arranged in a ring around one end of the bracket body, and are connected to the curved part of the bracket body near the proximal end.

13. A vascular covered stent according to claim 11, characterized in that: The fixing part is a barb.

14. A vascular covered stent according to claim 11, characterized in that: The length of the barbs is 1.2mm to 1.8mm.

15. A vascular covered stent according to claim 4, characterized in that: The area covered by the membrane at the proximal end extends beyond the area of ​​the stent body.

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