Automatic decalcification device for pathological bone specimen

By designing an automatic decalcification device, using a microcontroller, ultrasonic wave and calcium ion detector, the automated decalcification process of pathological bone specimens is realized, solving the problem of strong artificial dependence in the existing technology, and improving efficiency and automation.

CN222166683UActive Publication Date: 2024-12-13SUN YAT SEN MEMORIAL HOSPITAL SUN YAT SEN UNIV
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Patent Information

Application Number
CN202420630875.9
Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
Filing Date
2024-03-28
Publication Date
2024-12-13
Estimated Expiration
2034-03-28

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Abstract

The utility model discloses an automatic decalcification device for a pathological bone specimen. The automatic decalcification device comprises a box body, a decalcification mechanism and a spraying mechanism, a single chip microcomputer is fixedly connected to the front side face of the box body, the input end of the single chip microcomputer is electrically connected with an external power source, an ultrasonic mounting plate is arranged on the bottom wall of the box body, transducers which are evenly distributed are arranged in the ultrasonic mounting plate, and signal sources of the transducers are externally connected with an external ultrasonic generator; the decalcification mechanism comprises a sealing groove, a sealing ring, a rectangular plate and a pre-placing groove, the sealing groove is formed in the upper end of the box body, the sealing ring is in butt joint with the interior of the sealing groove, the rectangular plate is fixedly connected to the upper end of the sealing ring, and the pre-placing groove is formed in the upper surface of the rectangular plate; according to the automatic decalcification device for the pathological bone specimens, when the automatic decalcification device for the pathological bone specimens is used for decalcification of the pathological bone specimens, dependence on manpower is low, the automation degree is high, and the working process does not need to be manually supervised in real time.
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Description

Technical Field

[0001] The utility model relates to the technical field of medicine, in particular to an automatic decalcification device for pathological bone specimens. Background Art

[0002] When making slices in pathological experiments, we often encounter some calcium-containing tissues, and calcium is very hard. Due to the difference in density between calcium and paraffin in the tissue, calcium-containing tissues generally cannot be directly sliced, but need to be decalcified:

[0003] Existing decalcification methods often use tissue decalcification fluid, which often uses some strong organic acids, or inorganic acids such as hydrochloric acid and nitric acid, and then manually prepares the solution in real time. Based on the technician's experience, a pin is used to puncture the bone specimen to test its hardness to determine whether decalcification is complete.

[0004] There are some problems with this decalcification method of manually preparing solutions and judging by personnel in real time. For example, it is highly dependent on manual labor and requires staff to detect bone specimens in real time. For this reason, we propose an automatic decalcification device for pathological bone specimens. Utility Model Content

[0005] The technical problem to be solved by the utility model is to overcome the existing defects and provide an automatic decalcification device for pathological bone specimens, which has a high degree of automation and can effectively solve the problems in the background technology.

[0006] To achieve the above-mentioned purpose, the utility model provides the following technical solutions: an automatic decalcification device for pathological bone specimens, comprising a box body, a decalcification mechanism and a spray mechanism;

[0007] Box body: The front side thereof is fixedly connected with a single-chip microcomputer, the input end of the single-chip microcomputer is electrically connected to an external power supply, the bottom wall of the box body is provided with an ultrasonic mounting plate, the interior of the ultrasonic mounting plate is provided with evenly distributed transducers, and the signal source of the transducer is externally connected to an external ultrasonic generator;

[0008] Decalcification mechanism: It includes a sealing groove, a sealing ring, a rectangular plate and a pre-placement groove. The sealing groove is opened at the upper end of the box body, the sealing ring is connected to the inside of the sealing groove, the upper end of the sealing ring is fixedly connected to the rectangular plate, and the upper surface of the rectangular plate is opened with a pre-placement groove;

[0009] Spray mechanism: It is arranged on the upper inner side of the box body. When decalcifying pathological bone specimens, it has low dependence on manual labor, high degree of automation, and no need for manual real-time supervision of the workflow.

[0010] Furthermore, the decalcification mechanism also includes a docking groove, a docking block, a handle, a connecting block and a placement basket. The docking groove is symmetrically opened on the bottom wall of the pre-placement groove, the inside of the docking groove is slidably connected with a docking block, the lower end of the docking block is fixedly connected with a connecting block, the lower ends of the two connecting blocks are fixedly connected to the upper end of a placement basket, and a handle is fixedly connected between the two connecting blocks to realize the function of placing pathological bone specimens.

[0011] Furthermore, it also includes a cover plate, which is hinged to the left end of the rectangular plate through a pin shaft, and a handle is provided on the left side of the cover plate to achieve a sealing function.

[0012] Furthermore, the spray mechanism includes a water inlet pipe, an annular water pipe and a spray head. The annular water pipe is arranged on the upper side of the inner wall of the box body, a water inlet pipe is provided on the right side of the box body, the right end of the water inlet pipe is connected to an external water pump, and evenly distributed spray heads are provided on the lower side of the outer arc surface of the annular water pipe to realize the function of spraying and flushing.

[0013] Furthermore, it also includes a calcium ion detector, which is arranged on the lower middle side of the front side of the box body, and the measuring end of the calcium ion detector extends into the interior of the box body. The box body is bidirectionally electrically connected to the single-chip microcomputer to achieve the function of measuring calcium ions.

[0014] Furthermore, it also includes a water outlet, which is arranged on the lower side of the right side of the box body. The upper side of the right side of the box body is provided with a front-to-back symmetrical feed pipe. The middle part of the feed pipe is connected in series with an electronic metering valve. The input end of the electronic metering valve is electrically connected to the output end of the single-chip microcomputer. The water outlet is externally connected to an external wastewater treatment device, and the right end of the feed pipe is externally connected to an external feeding device to realize the function of water inlet and outlet.

[0015] Furthermore, it also includes a viewing window, which is symmetrically arranged on the front side of the box body. The bottom end of the box body is provided with a support foot, so that the pathological bone specimen in the box body can be observed.

[0016] Compared with the prior art, the beneficial effects of the utility model are: the automatic decalcification device for pathological bone specimens has the following advantages:

[0017] 1. When calcium ions of pathological bone specimens need to be removed, place the pathological bone specimens in the placement basket, manually lift the handle, and then refer to the position of the docking slot and the docking block, insert the docking block into the docking slot, and then close the cover. The cover is embedded in the pre-placement slot to complete the sealing of the box body and form a sealed working environment;

[0018] 2. During the process of pathological bone specimens, the electronic metering valve is opened, and a certain amount of reaction liquid is introduced into the box body through the feed pipe. The reaction liquid submerges the pathological bone specimens placed in the basket. At this time, the external ultrasonic generator can be regulated to transmit the ultrasonic signal to the transducer, and the transducer converts these signals into amplitude, and oscillates the pathological bone specimens in the reaction liquid in real time to accelerate the decalcification liquid to penetrate into the bone specimen for decalcification reaction. At this time, the single-chip microcomputer is regulated, and the calcium ion detector is operated. The calcium ion detector detects the calcium ion content of the reaction liquid every thirty minutes. When the calcium ion detector detects that the calcium ion concentration of the reaction liquid no longer changes, the external wastewater treatment equipment can be regulated to discharge the calcium ion-containing wastewater in the box body. At this time, the external water pump can be regulated, and the high-pressure water source continuously sprays the pathological bone specimen through the annular water pipe and the spray head to complete the flushing. At this time, the pathological bone specimen can be taken out, placed in a designated storage bottle, and a fixative is added to the storage bottle for storage. When decalcifying pathological bone specimens, the dependence on manual labor is low, the degree of automation is high, and there is no need for manual real-time supervision of the workflow. BRIEF DESCRIPTION OF THE DRAWINGS

[0019] Figure 1 It is a schematic diagram of the structure of the utility model;

[0020] Figure 2 It is a partial cross-sectional structural schematic diagram of the utility model;

[0021] Figure 3 This is an enlarged structural diagram of the utility model at A;

[0022] Figure 4 It is a schematic diagram of the structure of the utility model when viewed from above.

[0023] In the figure: 1 box body, 2 decalcification mechanism, 21 sealing groove, 22 sealing ring, 23 rectangular plate, 24 pre-placement groove, 25 docking groove, 26 docking block, 27 handle, 28 connecting block, 29 placement basket, 3 spray mechanism, 31 water inlet pipe, 32 annular water pipe, 33 spray head, 4 single chip microcomputer, 5 calcium ion detector, 6 legs, 7 ultrasonic mounting plate, 8 transducer, 9 visual window, 10 water outlet, 11 feed pipe, 12 cover plate, 13 handle. DETAILED DESCRIPTION

[0024] The following will be combined with the drawings in the embodiments of the utility model to clearly and completely describe the technical solutions in the embodiments of the utility model. Obviously, the described embodiments are only part of the embodiments of the utility model, not all of the embodiments. Based on the embodiments in the utility model, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the utility model.

[0025] See also Figure 1-4,This embodiment provides a technical solution: an automatic decalcification device for pathological bone specimens, comprising a box body 1, a decalcification mechanism 2 and a spray mechanism 3;

[0026] Box body 1: A single-chip microcomputer 4 is fixedly connected to the front side thereof, and the input end of the single-chip microcomputer 4 is electrically connected to an external power supply. An ultrasonic mounting plate 7 is provided on the bottom wall of the box body 1, and uniformly distributed transducers 8 are provided inside the ultrasonic mounting plate 7. The signal source of the transducer 8 is externally connected to an external ultrasonic generator. The box body 1 also includes a calcium ion detector 5, which is arranged on the lower middle side of the front side of the box body 1. The measuring end of the calcium ion detector 5 extends into the interior of the box body 1. The box body 1 is bidirectionally electrically connected to the single-chip microcomputer 4, and also includes a water outlet 10, which is arranged on the lower right side of the box body 1. A front-to-back symmetrical feed pipe 11 is provided on the upper right side of the box body 1. An electronic metering valve is connected in series in the middle of the feed pipe 11. The input end of the electronic metering valve is electrically connected to the output end of the single-chip microcomputer 4, and the water outlet 10 is externally connected to an external wastewater. The processing equipment, the right end of the feed pipe 11 is externally connected to the external feeding equipment, and also includes a visual window 9, which is symmetrically arranged on the front side of the box body 1. The bottom end of the box body 1 is provided with a support leg 6, and the device is placed on the designated workstation through the support leg 6, and the external ultrasonic generator is regulated to transmit the ultrasonic signal to the transducer 8, and the transducer 8 converts these signals into amplitude, and oscillates the pathological bone specimen in the reaction solution in real time to accelerate the decalcification solution to penetrate into the bone specimen for decalcification reaction. At this time, the single-chip microcomputer 4 is regulated, and the calcium ion detector 5 is operated. The calcium ion detector 5 detects the calcium ion content of the reaction solution every thirty minutes. When the calcium ion detector 5 detects that the calcium ion concentration of the reaction solution no longer changes, the external wastewater treatment equipment can be regulated to discharge the calcium ion-containing wastewater in the box body 1;

[0027] The decalcification mechanism 2 includes a sealing groove 21, a sealing ring 22, a rectangular plate 23 and a pre-placement groove 24. The sealing groove 21 is provided at the upper end of the box body 1. The sealing groove 21 is connected to the sealing ring 22. The upper end of the sealing ring 22 is fixedly connected to the rectangular plate 23. The upper surface of the rectangular plate 23 is provided with a pre-placement groove 24. The decalcification mechanism 2 also includes a docking groove 25, a docking block 26, a handle 27, a connecting block 28 and a placement basket 29. The docking groove 25 is symmetrically provided on the bottom wall of the pre-placement groove 24. The docking groove 25 is slidably connected to the docking block 26. The lower end of the docking block 26 is fixedly connected to the connecting block 28. The lower ends of the two connecting blocks 28 are fixed to the upper end of a placement basket 29. The two connecting blocks 28 are connected, and a handle 27 is fixedly connected between them. The cover plate 12 is also included. The cover plate 12 is hinged to the left end of the rectangular plate 23 through a pin shaft. The left side of the cover plate 12 is provided with a handle 13. The pathological bone specimen is placed in the placement basket 29. At this time, the handle 27 is manually lifted, and then the position of the docking groove 25 and the docking block 26 is referred to. The docking block 26 is inserted into the docking groove 25. At this time, the cover plate 12 is closed, and the cover plate 12 is embedded in the pre-placement groove 24 to complete the sealing of the box body 1. The single-chip microcomputer 4 is regulated, and the electronic metering valve is opened to allow a certain amount of reaction liquid to enter the interior of the box body 1 through the feeding pipe 11. The reaction liquid submerges the pathological bone specimen in the placement basket 29 at this time;

[0028] Spray mechanism 3: It is arranged on the upper side of the inner part of the box body 1. The spray mechanism 3 includes a water inlet pipe 31, an annular water pipe 32 and a spray head 33. The annular water pipe 32 is arranged on the upper side of the inner wall of the box body 1. The water inlet pipe 31 is arranged on the right side of the box body 1. The right end of the water inlet pipe 31 is connected to an external water pump. The lower side of the outer arc surface of the annular water pipe 32 is provided with evenly distributed spray heads 33. The external water pump is regulated, and the high-pressure water source continuously sprays the pathological bone specimen through the annular water pipe 32 and the spray head 33 to complete the flushing. At this time, the pathological bone specimen can be taken out and placed in a designated storage bottle, and fixative is added into the storage bottle for storage.

[0029] The working principle of an automatic decalcification device for pathological bone specimens provided by the utility model is as follows: the device is placed on a designated workstation via the support legs 6, at which time the pathological bone specimen is placed in the placement basket 29, the handle 27 is manually lifted, and the docking block 26 is inserted into the docking slot 25 with reference to the position of the docking slot 25 and the docking block 26, the cover plate 12 is closed, and the cover plate 12 is embedded in the pre-placement slot 24 to complete the sealing of the box body 1, the single-chip microcomputer 4 can be regulated at this time, the electronic metering valve is opened, and a certain amount of reaction liquid is introduced into the box body 1 through the feed pipe 11, and the reaction liquid submerges the pathological bone specimen in the placement basket 29, and at this time, the external ultrasonic generator can be regulated to transmit the ultrasonic signal The signals are then transmitted to the transducer 8, which then converts the signals into amplitudes, and oscillates the pathological bone specimen in the reaction solution in real time to accelerate the decalcification solution to penetrate into the bone specimen for decalcification reaction. At this time, the single chip microcomputer 4 is regulated to operate the calcium ion detector 5, which detects the calcium ion content of the reaction solution every thirty minutes. When the calcium ion detector 5 detects that the calcium ion concentration of the reaction solution no longer changes, the external wastewater treatment equipment can be regulated to discharge the calcium ion-containing wastewater in the box body 1. At this time, the external water pump can be regulated, and the high-pressure water source can continuously spray the pathological bone specimen through the annular water pipe 32 and the spray head 33 to complete the flushing. At this time, the pathological bone specimen can be taken out, placed in a designated storage bottle, and a fixative is added to the storage bottle for storage.

[0030] It is worth noting that the single chip microcomputer 4 disclosed in the above embodiment is specifically model S7-200, and the calcium ion detector 5, the electronic metering valve and the transducer 8 can be freely configured according to the actual application scenario. The calcium ion detector 5 is recommended to use the MHY-29345 industrial online calcium ion detector, the electronic metering valve is recommended to use the EVE2000 intelligent flow control integrated valve, and the transducer 8 is recommended to use the YTH series ultrasonic transducer. The single chip microcomputer 4 controls the calcium ion detector 5 and the electronic metering valve using methods commonly used in the prior art.

[0031] The above description is only an embodiment of the present invention, and does not limit the patent scope of the present invention. Any equivalent structure or equivalent process transformation made by using the contents of the specification and drawings of the present invention, or directly or indirectly applied in other related technical fields, are also included in the patent protection scope of the present invention.

Claims

1. An automatic decalcification device for pathological bone specimens, characterized in that: It comprises a box body (1), a decalcification mechanism (2) and a spraying mechanism (3); The box body (1) has a single-chip microcomputer (4) fixedly connected to its front side, the input end of the single-chip microcomputer (4) is electrically connected to an external power source, the bottom wall of the box body (1) is provided with an ultrasonic mounting plate (7), the interior of the ultrasonic mounting plate (7) is provided with uniformly distributed transducers (8), and the signal source of the transducer (8) is externally connected to an external ultrasonic generator; The decalcification mechanism (2) comprises a sealing groove (21), a sealing ring (22), a rectangular plate (23) and a pre-placement groove (24); the sealing groove (21) is provided at the upper end of the box body (1); the sealing ring (22) is butt-jointed inside the sealing groove (21); the upper end of the sealing ring (22) is fixedly connected to the rectangular plate (23); and the upper surface of the rectangular plate (23) is provided with the pre-placement groove (24); Spraying mechanism (3): It is arranged on the upper side of the interior of the box body (1).

2. The automatic decalcification device for pathological bone specimens according to claim 1, characterized in that: The decalcification mechanism (2) further comprises a docking groove (25), a docking block (26), a handle (27), a connecting block (28) and a placement basket (29); the docking groove (25) is symmetrically arranged on the bottom wall of the pre-placement groove (24); the interior of the docking groove (25) is slidably connected with a docking block (26); the lower ends of the docking blocks (26) are fixedly connected with connecting blocks (28); the lower ends of the two connecting blocks (28) are fixedly connected to the upper end of a placement basket (29); and the handle (27) is fixedly connected between the two connecting blocks (28).

3. The automatic decalcification device for pathological bone specimens according to claim 1, characterized in that: It also comprises a cover plate (12), wherein the cover plate (12) is hinged to the left end of the rectangular plate (23) via a pin shaft, and a handle (13) is provided on the left side of the cover plate (12).

4. The automatic decalcification device for pathological bone specimens according to claim 1, characterized in that: The spray mechanism (3) comprises a water inlet pipe (31), an annular water pipe (32) and a spray head (33); the annular water pipe (32) is arranged on the upper side of the inner wall of the box body (1); the water inlet pipe (31) is arranged on the right side of the box body (1); the right end of the water inlet pipe (31) is externally connected to an external water pump; and the spray heads (33) are evenly distributed on the lower side of the outer arc surface of the annular water pipe (32).

5. The automatic decalcification device for pathological bone specimens according to claim 1, characterized in that: It also comprises a calcium ion detector (5), which is arranged on the lower middle side of the front side of the box body (1), and the measuring end of the calcium ion detector (5) extends into the interior of the box body (1), and the box body (1) is bidirectionally electrically connected to the single-chip computer (4).

6. The automatic decalcification device for pathological bone specimens according to claim 1, characterized in that: The box body (1) further comprises a water outlet (10), the water outlet (10) being arranged on the lower side of the right side surface of the box body (1), a front-to-rear symmetrical feed pipe (11) being arranged on the upper side of the right side surface of the box body (1), an electronic metering valve being connected in series in the middle of the feed pipe (11), an input end of the electronic metering valve being electrically connected to an output end of the single-chip computer (4), the water outlet (10) being externally connected to an external wastewater treatment device, and the right end of the feed pipe (11) being externally connected to an external decalcification solution storage tank.

7. The automatic decalcification device for pathological bone specimens according to claim 1, characterized in that: It also comprises a visual window (9), which is symmetrically arranged on the front side of the box body (1), and a supporting foot (6) is arranged at the bottom end of the box body (1).