Detection circuit for blood glucose testing device

Abstract

The utility model discloses a detection circuit for a blood glucose testing device, the blood glucose testing device comprises a test paper reaction unit and a processing unit, and the test paper reaction unit comprises an impedance testing electrode pair and a current testing electrode pair; the processing unit comprises an impedance detection module, a current detection module and a potential tracking module, the impedance detection module is connected with the impedance test electrode pair and used for testing the impedance of the blood glucose sample, the impedance detection module comprises a signal generator, and the signal generator is used for applying an alternating current signal or a direct current signal to the impedance test electrode pair; the current detection module and the potential tracking module are respectively connected with the current test electrode pair, the current detection module can apply excitation voltage to the current test electrode pair for testing the current of the blood glucose sample, and after the excitation voltage is disconnected, the potential tracking module can test the attenuation potential of the current test electrode pair. The attenuation potential is measured, and the attenuation potential can be used as one of blood glucose calibration parameters, so that the blood glucose detection accuracy can be improved.

Description

Technical Field

[0001] The present application relates to the field of blood sugar testing, and in particular to a detection circuit for a blood sugar testing device. Background Art

[0002] At present, the blood glucose measuring devices on the market generally use the electrochemical method principle to measure human blood glucose. The specific implementation principle is that when blood is sucked into the test paper reaction area, the enzyme in the test paper reaction area will catalyze the redox reaction of glucose in the blood and generate a weak current. After the instrument detects the weak current through the sensor, it is converted into a blood glucose concentration value through a specific algorithm. Although this method has been widely used in blood glucose measuring devices on the market, there is still a lot of room for improvement in accuracy. In whole blood samples, the hematocrit level (i.e., HCT) has a great impact on the blood glucose measurement results. In the latest national standards for blood glucose testing, the accuracy requirement for blood glucose measurement is not more than ±20%. However, for some special anemic people, such as pregnant women, their HCT is very low; for children and even newborns, their HCT is very high. Therefore, for the above-mentioned groups of people, if the blood glucose measuring device does not have an HCT calibration function, it will greatly affect the accuracy of the measurement. In addition, due to the influence of factors such as the environment and production process, the test paper electrodes and the sensor electrodes in the blood glucose measuring device will also show different phenomena in the discharge characteristics, which will affect the entire current detection process, thereby affecting the accuracy of the blood glucose measurement results. Utility Model Content

[0003] In order to solve the above problems, the present application proposes a detection circuit for a blood sugar testing device, wherein the blood sugar testing device comprises a test paper reaction unit and a processing unit, wherein the test paper reaction unit comprises an impedance testing electrode pair and a current testing electrode pair, and the test paper reaction unit can be electrically connected to the processing unit;

[0004] The processing unit includes an impedance detection module, a current detection module and a potential tracking module. When the test paper reaction unit is electrically connected to the processing unit,

[0005] The impedance detection module is connected to the impedance test electrode pair and is used to test the impedance of the blood glucose sample. The impedance detection module includes a signal generator, and the signal generator is used to apply an AC signal or a DC signal to the impedance test electrode pair. The current detection module and the potential tracking module are respectively connected to the current test electrode pair. The current detection module can apply an excitation voltage to the current test electrode pair to test the current of the blood glucose sample. After the excitation voltage is disconnected, the potential tracking module can test the attenuation potential of the current test electrode pair.

[0006] In one example, the impedance testing electrode pair includes a first electrode and a second electrode;

[0007] The impedance detection module further includes a first operational amplifier, the signal generator is connected to the first electrode, and the first operational amplifier is connected to the second electrode.

[0008] In one example, the current testing electrode pair includes a third electrode and a fourth electrode;

[0009] The current detection module includes a second operational amplifier, the third electrode is grounded or connected to a fixed level through a switch, and the second operational amplifier is connected to the fourth electrode through a switch.

[0010] In one example, the potential tracking module includes a fourth operational amplifier;

[0011] The potential tracking module is connected to the third electrode and the fourth electrode respectively through switches.

[0012] In one example, the test paper reaction unit further includes a sample injection detection electrode, the processing unit further includes a sample injection detection module, and the sample injection detection module includes a third operational amplifier;

[0013] The sampling detection module is connected to the sampling detection electrode through a switch. Based on the third operational amplifier, the sampling detection module detects whether the blood sugar sample covers the test paper reaction unit through the sampling detection electrode.

[0014] In one example, one of the impedance testing electrode pairs is electrically connected to one of the current testing electrode pairs.

[0015] The detection circuit for the blood sugar testing device proposed in this application can bring the following beneficial effects:

[0016] Compared with the traditional scheme, the utility model has the following advantages: firstly, the circuit of the blood glucose measuring device can not only detect the current related to the blood glucose concentration through the blood glucose measuring module, but also identify whether the blood is filled in the reaction area of ​​the test strip through the sampling detection module, thereby preventing inaccurate measurement due to insufficient blood sampling; secondly, the circuit of the blood glucose measuring device can detect the hematocrit level (HCT) in the blood through the impedance detection module, and then realize the correction of the blood glucose result through the HCT; finally, the circuit of the blood glucose measuring device can detect the attenuation potential of the test strip electrode through the potential tracking module, and can further correct the blood glucose result, thereby finally improving the accuracy of the blood glucose detection result. BRIEF DESCRIPTION OF THE DRAWINGS

[0017] The drawings described herein are used to provide a further understanding of the present application and constitute a part of the present application. The illustrative embodiments of the present application and their descriptions are used to explain the present application and do not constitute an improper limitation on the present application. In the drawings:

[0018] Figure 1 is a schematic diagram of a detection circuit in an embodiment of the present application;

[0019] Figure 2 This is a schematic diagram of a blood glucose test strip in an embodiment of the present application;

[0020] Among them, 100 is a test paper reaction unit, 101 is an impedance detection module, 102 is a current detection module, 103 is a sample injection detection module, and 104 is a potential tracking module. DETAILED DESCRIPTION

[0021] In order to more clearly illustrate the overall concept of the present invention, a detailed description is given below in the form of examples in conjunction with the accompanying drawings.

[0022] In the following description, many specific details are set forth to facilitate a full understanding of the present invention. However, the present invention may also be implemented in other ways different from those described herein. Therefore, the protection scope of the present invention is not limited to the specific embodiments disclosed below.

[0023] In addition, in the description of the present invention, it should be understood that the terms "top", "bottom", "inside", "outside", "axial", "radial", "circumferential", etc., indicating orientations or positional relationships, are based on the orientations or positional relationships shown in the accompanying drawings, and are only for the convenience of describing the present invention and simplifying the description, and do not indicate or imply that the device or element referred to must have a specific orientation, be constructed and operated in a specific orientation, and therefore cannot be understood as a limitation on the present invention.

[0024] In the present invention, unless otherwise clearly specified and limited, the terms "install", "connect", "connect", "fix" and the like should be understood in a broad sense, for example, it can be a fixed connection, a detachable connection, or an integral connection; it can be a mechanical connection, an electrical connection, or a communication; it can be a direct connection, or an indirect connection through an intermediate medium, it can be the internal connection of two elements or the interaction relationship between two elements. For ordinary technicians in this field, the specific meanings of the above terms in the present invention can be understood according to specific circumstances.

[0025] In the present utility model, unless otherwise clearly specified and limited, the first feature "above" or "below" the second feature may be that the first and second features are in direct contact, or the first and second features are in indirect contact through an intermediate medium. In the description of this specification, the description with reference to the terms "one embodiment", "some embodiments", "example", "specific example", or "some examples" means that the specific features, structures, materials or characteristics described in conjunction with the embodiment or example are included in at least one embodiment or example of the utility model. In this specification, the schematic representation of the above terms does not necessarily refer to the same embodiment or example. Moreover, the specific features, structures, materials or characteristics described may be combined in an appropriate manner in any one or more embodiments or examples.

[0026] like Figure 1 As shown, the embodiment of the present application provides a detection circuit for a blood sugar test device, and the detection circuit is built in the blood sugar test device. The blood sugar test device includes a test strip reaction unit 100 and a processing unit. The test strip reaction unit 100 is used to connect with a blood sugar test strip. The blood sugar test strip and the detection circuit can be independent detachable structures or integrated fixed structures.

[0027] like Figure 2 As shown, the blood glucose test strip includes multiple electrodes, namely, electrode A to electrode E. The upper ends of these multiple electrodes are used to place the blood glucose sample to be tested, and the lower ends are connected to the corresponding electrode interfaces (interface A to interface E) in the test strip reaction unit 100. The electrodes in the blood glucose test strip correspond to the electrode interfaces in the test strip reaction unit 100 one by one. For the convenience of description, when describing below, if no additional explanation is given, it is assumed that the blood glucose test strip is connected to the test strip reaction unit 100.

[0028] Based on this, the multiple electrodes included in the test paper reaction unit 100 are combined, and corresponding electrode pairs can be formed according to the different combined electrodes, and the processing units connected to each electrode pair have corresponding functions according to the different structures.

[0029] Specifically, the test paper reaction unit includes at least an impedance test electrode pair and a current test electrode pair. The impedance test electrode pair is composed of electrode A and electrode B, which are connected to the impedance detection module 101 in the processing unit, and the current test electrode is composed of electrode C and electrode D, which are connected to the current detection module 102 and the potential tracking module 104 in the processing unit.

[0030] The impedance detection module 101 is used to test the impedance of the blood glucose sample. Figure 1 As shown, a signal generator is included, which can apply an AC signal or a DC signal to the impedance test electrode pair based on demand.

[0031] The current detection module 102 can apply an excitation voltage to the current test electrode pair to test the current of the blood glucose sample. After the excitation voltage is disconnected, the potential tracking module 104 can test the attenuation potential of the current test electrode pair.

[0032] Compared with the traditional solution, which only detects the current to obtain the blood sugar value in the blood sugar sample, the decay potential of the current test electrode pair can also be measured. The decay potential can be used as one of the blood sugar calibration parameters to improve the accuracy of blood sugar detection.

[0033] In one embodiment, the impedance test electrode pair includes a first electrode (i.e. Figure 1 The electrode A in the Figure 1 At this time, the impedance detection module 101 also includes a first operational amplifier OP1, a signal generator is connected to the first electrode, and the first operational amplifier OP1 is connected to the second electrode. The signal generator applies an AC signal or a DC signal to both ends of the impedance test electrode pair based on demand, and realizes impedance detection through the operational amplifier OP1.

[0034] In one embodiment, the current testing electrode pair includes a third electrode (i.e. Figure 1 The electrode C in the middle), the fourth electrode (i.e. Figure 1 The current detection module 102 includes a second operational amplifier OP2, the third electrode is grounded through a switch, and the second operational amplifier OP2 is connected to the fourth electrode through a switch. When the blood in the blood sugar sample is sucked into the test paper reaction unit, an excitation voltage V is applied between the current test electrode pair, and the glucose enzyme reacts with the glucose in the blood sugar sample to generate a weak current. The weak current in the current test electrode pair is detected by the second operational amplifier OP2 and then converted into a blood sugar value.

[0035] Further, the potential tracking module 104 includes a fourth operational amplifier OP4. The potential tracking module 104 is connected to the third electrode and the fourth electrode through switches. By adopting a double pulse excitation method, when the excitation voltage at both ends of the current test electrode pair is disconnected, the attenuation potential of the third electrode and the fourth electrode can be detected by the potential tracking module 104, so that it can be used for the detection of blood sugar value, thereby increasing the detection accuracy.

[0036] In one embodiment, the test paper reaction unit 100 further includes a sample injection detection electrode (i.e. Figure 1 and Figure 2 The processing unit further includes an injection detection module 103, and the injection detection module 103 includes a third operational amplifier OP3.

[0037] The sampling detection module 103 is connected to the sampling detection electrode through a switch. The sampling detection module 103 is based on the third operational amplifier OP3. It detects whether the blood glucose sample covers the test paper reaction unit 100 through the sampling detection electrode, and then determines whether the test paper reaction unit is full of blood. Only when it is full, the corresponding blood glucose value will be detected.

[0038] In one embodiment, one of the impedance test electrode pairs is electrically connected to one of the current test electrode pairs, such as Figure 2 As shown, electrode A and electrode C may be electrically connected, and electrode B and electrode D may be electrically connected.

[0039] The above is only an embodiment of the present application and is not intended to limit the present application. For those skilled in the art, the present application may have various changes and variations. Any modification, equivalent replacement, improvement, etc. made within the spirit and principle of the present application should be included in the scope of the claims of the present application.

Claims

1. A detection circuit for a blood sugar testing device, the blood sugar testing device comprising a test strip reaction unit and a processing unit, characterized in that: The test paper reaction unit includes an impedance test electrode pair and a current test electrode pair, and the test paper reaction unit can be electrically connected to the processing unit; The processing unit includes an impedance detection module, a current detection module and a potential tracking module. When the test paper reaction unit is electrically connected to the processing unit, The impedance detection module is connected to the impedance test electrode pair and is used to test the impedance of the blood glucose sample. The impedance detection module includes a signal generator, and the signal generator is used to apply an AC signal or a DC signal to the impedance test electrode pair. The current detection module and the potential tracking module are respectively connected to the current test electrode pair. The current detection module can apply an excitation voltage to the current test electrode pair to test the current of the blood glucose sample. After the excitation voltage is disconnected, the potential tracking module can test the attenuation potential of the current test electrode pair.

2. The detection circuit for a blood sugar testing device according to claim 1, characterized in that: The impedance testing electrode pair includes a first electrode and a second electrode; The impedance detection module further includes a first operational amplifier, the signal generator is connected to the first electrode, and the first operational amplifier is connected to the second electrode.

3. The detection circuit for a blood sugar testing device according to claim 1, characterized in that: The current testing electrode pair includes a third electrode and a fourth electrode; The current detection module includes a second operational amplifier, the third electrode is grounded or connected to a fixed potential through a switch, and the second operational amplifier is connected to the fourth electrode through a switch.

4. The detection circuit for a blood sugar testing device according to claim 3, characterized in that: The potential tracking module includes a fourth operational amplifier; The potential tracking module is connected to the third electrode and the fourth electrode respectively through switches.

5. The detection circuit for a blood sugar testing device according to claim 1, characterized in that: The test paper reaction unit further includes a sample injection detection electrode, the processing unit further includes a sample injection detection module, and the sample injection detection module includes a third operational amplifier; The sampling detection module is connected to the sampling detection electrode through a switch. Based on the third operational amplifier, the sampling detection module detects whether the blood sugar sample covers the test paper reaction unit through the sampling detection electrode.

6. The detection circuit for a blood sugar testing device according to claim 1, characterized in that: One of the impedance testing electrode pairs is electrically connected to one of the current testing electrode pairs.

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