Pipetting device

Abstract

The utility model belongs to the technical field of pipettors, and discloses a pipetting device. The pipetting device comprises an installation part, a first pipettor and a second pipettor, the first pipettor is arranged on the installation part in a lifting mode, and the first pipettor is provided with a first pipetting channel; the second pipettor is arranged on the mounting part in a lifting manner, the second pipettor is provided with at least two second pipetting channels, and the first pipettor and the second pipettor can be respectively and selectively moved to pipetting stations. The pipetting device can meet the requirements of one-time single operation and batch operation, the equipment cost is reduced, and the compatibility is good.

Description

Technical Field

[0001] The utility model relates to the technical field of pipettes, in particular to a pipetting device. Background Art

[0002] In modern biological science and biotechnology, pipettes are commonly used experimental tools, often used to transfer small or trace amounts of liquid. They appear in various links, such as sample processing and testing. The accuracy of pipettes plays a vital role in discovering scientific research results.

[0003] Existing pipettes are generally single-channel or multi-channel. Multi-channel pipettes usually have 8, 24, 48, 96, and other specifications of the number of channels. When using a single-channel pipette, only one tip is used to transfer liquid, which is convenient to operate; multi-channel pipettes can usually use one or more columns of channels and perform batch transfer through multiple tips. Single-channel and multi-channel pipettes are applicable to different scenarios. In order to meet the needs of the experiment, it is necessary to select single-channel pipettes and multi-channel pipettes according to the needs. The equipment cost is high and the operation is inconvenient. Utility Model Content

[0004] The utility model aims to provide a liquid transfer device, which can solve the problem that a single-channel liquid transfer device and a multi-channel liquid transfer device need to be used separately, resulting in high equipment cost and inconvenient operation.

[0005] To achieve this purpose, the utility model adopts the following technical solutions:

[0006] A liquid transfer device, comprising:

[0007] Mounting parts;

[0008] A first pipette, wherein the first pipette is movably disposed on the mounting member, and the first pipette is provided with a first pipetting channel;

[0009] a second pipette, the second pipette being movably disposed on the mounting member, the second pipette being provided with at least two second pipetting channels;

[0010] The first pipette and the second pipette can be selectively moved to the pipetting station respectively.

[0011] As an optional solution of the above-mentioned pipetting device, in the second pipette, the volumes of any two of the second pipetting channels are the same, or the volumes of at least two of the second pipetting channels are different;

[0012] And / or, the volume of the first pipetting channel is different from the volume of at least one of the second pipetting channels.

[0013] As an optional solution of the above-mentioned pipetting device, the first pipette and the second pipette both include a pipette body and a pipette tip, a piston cavity is formed in the pipette body, the pipette tip is detachably connected to the pipette body, and the pipette tip is connected to the piston cavity to form a pipetting channel.

[0014] As an optional solution of the above-mentioned pipetting device, the pipette body includes a universal adapter, and the universal adapter is detachable and connectable to the pipette tip, and the universal adapter can connect the pipette tips of at least two capacities.

[0015] As an optional solution of the above-mentioned pipetting device, the first pipette and the second pipette further include a pipetting drive assembly and a piston rod, the piston rod is arranged in the piston cavity, and the pipetting drive assembly is connected to the piston rod to drive the piston rod to reciprocate in the piston cavity to change the effective volume of the piston cavity;

[0016] The first pipette and / or the second pipette further comprises a transfer linkage assembly, and the linkage assembly can cooperate with the piston rod or the pipetting drive assembly to push the pipetting tip to be disengaged from the pipette body.

[0017] As an optional solution of the above-mentioned pipetting device, the linkage assembly includes:

[0018] A guide rod, wherein the guide rod is parallel to the piston rod, the guide rod is slidably disposed in the pipette body, and an end of the guide rod facing away from the pipette tip can abut against the piston rod or the pipette drive assembly;

[0019] A pusher, disposed at one end of the guide rod close to the pipette tip, the pusher being capable of abutting against the pipette tip;

[0020] An elastic member, connecting the guide rod and the pipette body, the elastic member being used to drive the guide rod to move in a direction away from the pipette tip;

[0021] Or, the linkage component includes:

[0022] A guide rod, wherein the guide rod is parallel to the piston rod, the guide rod is slidably disposed in the pipette body, and an end of the guide rod facing away from the pipette tip can abut against the piston rod or the pipette drive assembly;

[0023] A pusher, slidably disposed in the pipette body, one end of the pusher being able to abut against the guide rod, and the other end being able to abut against the pipette tip;

[0024] An elastic member connects the pushing member and the pipette body, and the elastic member is used to drive the pushing member to move in a direction away from the pipette tip.

[0025] As an optional solution of the above-mentioned pipetting device, in the second pipette, the pushing member can abut against each of the pipetting tips in the second pipette.

[0026] As an optional solution of the above-mentioned pipetting device, the first pipette and the second pipette can be both movably arranged on the mounting member, and the first pipette and the second pipette can be selectively lifted and lowered respectively.

[0027] As an optional solution of the above-mentioned pipetting device, the pipetting device further includes:

[0028] a first lifting mechanism, which is disposed on the mounting member and connected to the first pipette and is used to drive the first pipette to move up and down;

[0029] a first position detection member, the first position detection member being communicatively connected to the first lifting mechanism, and the first position detection member being capable of being triggered by the first pipette located at the pipetting station;

[0030] And / or, the pipetting device further comprises:

[0031] A second lifting mechanism, which is disposed on the mounting member and connected to the second pipette and is used to drive the second pipette to move up and down;

[0032] A second position detection component is communicatively connected with the second lifting mechanism, and the second position detection component can be triggered by the second pipette located at the pipetting station.

[0033] As an optional solution of the above-mentioned pipetting device, the first pipette and the second pipette are both slidably disposed on the mounting member, and the first pipette is disposed on one side of the second pipette.

[0034] Beneficial effects of the utility model:

[0035] In the pipetting device provided by the utility model, the first pipette is a single-channel pipette, which can perform a single pipetting operation at one time, and the second pipette is a multi-channel pipette, which can perform a batch pipetting operation at one time. The first pipette and the second pipette are integrated on a mounting part, and the first pipette and the second pipette can be respectively selected to move to the pipetting station, so that the first pipette or the second pipette can be selected for operation according to actual needs. The needs of one-time single operation and batch operation can be met by one pipetting device, thereby reducing equipment costs and having good compatibility. BRIEF DESCRIPTION OF THE DRAWINGS

[0036] Figure 1 This is a front view of the liquid transfer device provided by the utility model;

[0037] Figure 2 It is a front view of the second pipette provided by the utility model;

[0038] Figure 3 yes Figure 2 Middle AA section view;

[0039] Figure 4 It is a structural schematic diagram of a second pipette provided by the utility model;

[0040] Figure 5 yes Figure 2 Middle BB section view;

[0041] Figure 6 It is a side view of the first pipette provided by the utility model;

[0042] Figure 7 It is a front view of the first pipette provided by the utility model;

[0043] Figure 8 This is a schematic diagram of the structure of the liquid transfer device provided by the utility model. Figure 1 ;

[0044] Fig. 9 This is a schematic diagram of the structure of the liquid transfer device provided by the utility model. Figure 2 .

[0045] In the figure:

[0046] 10. Mounting member; 20. First pipette; 21. First pipette body; 211. First protective cover; 212. First piston cylinder; 213. First gun head adapter; 214. First piston rod; 22. First pipette tip; 23. First pipette drive assembly; 231. First pipette motor; 232. First pipette lead screw; 233. First pipette nut; 241. First guide rod; 242. First push member; 243. First elastic member; 25. First pipette mounting plate; 251. Upper limit member; 252. Lower limit member; 30. Second pipette; 31. Second pipette body; 311. Second protective cover; 312. Second piston cylinder; 313. Second gun head adapter; 314. Second piston rod; 32. Second pipette tip; 33. Second pipette drive assembly Component; 331, second pipetting motor; 332, second pipetting screw; 333, second pipetting nut; 334, second pipetting guide rail; 335, second pipetting slider; 34, second linkage assembly; 341, second guide rod; 342, second elastic component; 343, second pusher; 35, second pipetting mounting plate; 40, first lifting mechanism; 41, first motor seat; 42, first lifting motor; 43, first lifting screw; 44, first lifting nut; 45, first lifting guide rail; 46, first rotary support seat; 50, second lifting mechanism; 51, second motor seat; 52, second lifting motor; 53, second lifting screw; 54, second lifting nut; 55, adapter; 56, second lifting guide rail; 61, first position detection component; 62, second position detection component. DETAILED DESCRIPTION

[0047] The present invention is further described in detail below in conjunction with the accompanying drawings and embodiments. It is to be understood that the specific embodiments described herein are only used to explain the present invention, rather than to limit the present invention. It should also be noted that, for ease of description, only the parts related to the present invention, rather than all structures, are shown in the accompanying drawings.

[0048] In the description of the present invention, unless otherwise clearly specified and limited, the terms "connected", "connected", and "fixed" should be understood in a broad sense, for example, it can be a fixed connection, a detachable connection, or an integral connection; it can be a mechanical connection or an electrical connection; it can be a direct connection or an indirect connection through an intermediate medium, it can be the internal connection of two elements or the interaction relationship between two elements. For ordinary technicians in this field, the specific meanings of the above terms in the present invention can be understood according to specific circumstances.

[0049] In the present utility model, unless otherwise clearly specified and limited, a first feature being "above" or "below" a second feature may include that the first and second features are in direct contact, or may include that the first and second features are not in direct contact but are in contact through another feature between them. Moreover, a first feature being "above", "above" and "above" a second feature includes that the first feature is directly above and obliquely above the second feature, or simply indicates that the first feature is higher in level than the second feature. A first feature being "below", "below" and "below" a second feature includes that the first feature is directly below and obliquely below the second feature, or simply indicates that the first feature is lower in level than the second feature.

[0050] In the description of this embodiment, the terms "upper", "lower", "right", etc., are based on the directions or positions shown in the drawings, and are only for the convenience of description and simplified operation, rather than indicating or implying that the device or element referred to must have a specific direction, be constructed and operated in a specific direction, and therefore cannot be understood as a limitation of the present invention. In addition, the terms "first" and "second" are only used to distinguish in the description and have no special meaning.

[0051] This embodiment provides a liquid transfer device that can be used for transferring liquids. Figure 1 As shown, the pipetting device includes a mounting member 10, a first pipette 20 and a second pipette 30. The first pipette 20 and the second pipette 30 are both movably arranged on the mounting member 10, so that the first pipette 20 and the second pipette 30 can be respectively selected to move to the pipetting station, so as to select the first pipette 20 or the second pipette 30 to perform the liquid pipetting operation according to actual needs. Among them, the first pipette 20 is provided with a first pipetting channel, and the first pipette 20 can suck or discharge the liquid into the first pipetting channel; the second pipette 30 is provided with at least two second pipetting channels, and the second pipette 30 can suck or discharge the liquid into the second pipetting channel.

[0052] It can be understood that the first pipette 20 and the second pipette 30 can move independently, and both can move to the pipetting station at the same time, or only one of them can move to the pipetting station.

[0053] In this embodiment, the first pipette 20 is a single-channel pipette that can perform a single pipetting operation at one time, and the second pipette 30 is a multi-channel pipette that can perform a batch pipetting operation at one time. The first pipette 20 and the second pipette 30 are integrated on the mounting part 10. According to actual needs, the first pipette 20 or the second pipette 30 is selected to be moved to the pipetting station for operation. One pipetting device can meet the needs of one-time single operation and batch operation, thereby reducing equipment costs and having good compatibility.

[0054] like Figure 1As shown, the first pipette 20 and the second pipette 30 are both arranged on the mounting member 10, and the first pipette 20 and the second pipette 30 can be moved to the pipetting station by lifting, and the first pipette 20 and the second pipette 30 can be selectively lifted and lowered respectively, that is, the lifting and lowering of the first pipette 20 and the second pipette 30 are independent. In order to improve the stability of the movement of the first pipette 20 and the second pipette 30, the first pipette 20 and the second pipette 30 can be slidably arranged on the mounting member 10.

[0055] The first pipetting channel and the second pipetting channel extend vertically, and the openings are both arranged downwards, so as to take and place the liquid after moving downwards to the pipetting station.

[0056] In this embodiment, the volume of each second pipetting channel in the second pipette 30 is the same. The volume of the second pipetting channel can be designed to be smaller to meet the batch transfer requirements of a small amount of liquid. The volume of the first pipetting channel is different from the volume of the second pipetting channel. The volume of the first pipetting channel can be designed to be larger to meet the pipetting requirements.

[0057] Optionally, the volume of the first pipetting channel may be greater than the volume of the second pipetting channel to ensure that the total amount of liquid pipetted at a single time meets usage requirements.

[0058] In other embodiments, the volumes of at least two second pipetting channels in the second pipette 30 are different to meet different pipetting requirements.

[0059] The first pipette 20 and the second pipette 30 both include a pipette body and a pipette tip. A piston cavity is formed in the pipette body. The pipette tip is connected to the pipette body, and the pipette tip is communicated with the piston cavity to form a pipetting channel.

[0060] For the convenience of introduction, the pipette body and the pipette tip in the first pipette 20 are respectively the first pipette body 21 and the first pipette tip 22, the piston cavity in the first pipette body 21 is the first piston cavity, the first piston cavity is connected with the first pipette tip 22 to form a first pipette channel; the pipette body and the pipette tip in the second pipette 30 are respectively the second pipette body 31 and the second pipette tip 32, the piston cavity in the second pipette body 31 is the second piston cavity, the second piston cavity is connected with the second pipette tip 32 to form a second pipette channel.

[0061] In this embodiment, the second pipette 30 includes eight second pipette tips 32, which are arranged in a row, and the capacities of the eight second pipette tips 32 may be the same. In other embodiments, the number of second pipette tips 32 in the second pipette 30 may be set as needed, and may be less than eight, such as six or seven, or more than eight, such as nine, ten, eleven or more. The plurality of second pipette tips 32 may be arranged in one row, or in two or more rows.

[0062] Since the amount of liquid transferred by the pipetting device each time is small, the capacity of the active pipetting channel is mainly based on the capacity of the pipetting tip. In order to adjust the specifications of the pipetting tip according to needs, thereby adjusting the capacity of the pipetting channel, the pipetting tip and the pipette body can be detachably connected to facilitate the replacement of the appropriate pipetting tip according to needs.

[0063] Specifically, Figure 2 and Figure 3 As shown, the second pipette body 31 includes a second piston cylinder 312 and a gun tip adapter (hereinafter, the gun tip adapter in the second pipette 30 is referred to as the second gun tip adapter 313), a plurality of second piston cavities are formed in the second piston cylinder 312, and a piston rod (hereinafter, the piston rod in the second pipette 30 is referred to as the second piston rod 314) is slidably arranged in the second piston cavity; the second gun tip adapter 313 has a channel, one end of the second gun tip adapter 313 is connected to the second piston cylinder 312 body, and the other end is used for detachably connecting the second pipette tip 32. The second piston rod 314 slides in the second piston cavity, and can adjust the effective volume of the second piston cavity, so as to suck the liquid into the second pipette tip 32 or discharge it from the second pipette tip 32.

[0064] In this embodiment, the capacity of the second pipetting tip 32 is 250 μL, and the capacities of the plurality of second pipetting tips 32 are the same.

[0065] In other embodiments, the capacity of the second pipette tip 32 can be 50 μL-1000 μL, for example, 50 μL, 70 μL, 100 μL, 125 μL, 150 μL, 175 μL, 200 μL, 225 μL, 250 μL, 275 μL, 300 μL, 325 μL, 350 μL, 375 μL, 400 μL, 425 μL, 450 μL, The specific capacity of the second pipette tip 32 can be selected according to needs.

[0066] In other embodiments, among the plurality of second pipette tips 32 , at least two second pipette tips 32 may have different capacities, so that the second pipette 30 has better compatibility and can meet different usage requirements.

[0067] To facilitate the adjustment of the model of the second pipetting tip 32 as needed, the second pipetting tip 32 is detachably connected to the second pipetting body. Specifically, the second pipetting tip 32 is detachably connected to the second gun head adapter 313 to facilitate the adjustment of the model of the second pipetting tip 32 according to the amount of pipetting required.

[0068] For easy disassembly and assembly, the second pipette tip 32 is sleeved with the second gun tip adapter 313, and the second pipette tip 32 can be fixed on the second gun tip adapter 313 by tight fit. The second pipette tip 32 is sleeved on the second gun tip adapter 313, and a clamping protrusion is provided on the outer wall of the second gun tip adapter 313. When the second pipette tip 32 is sleeved on the second gun tip adapter 313, the clamping protrusion can abut against the inner wall of the second pipette tip 32, so as to achieve a tight fit between the second pipette tip 32 and the second gun tip adapter 313, thereby fixing the two.

[0069] The second pipette tip 32 and the second gun head adapter 313 are fixed by the above structure, and the two can be assembled by pressing and disassembled by pushing and pulling the second pipette tip 32. The operation is simple and convenient for replacing second pipette tips 32 of different models.

[0070] In this embodiment, the second gun tip adapter 313 is a universal adapter, which can connect at least two types of pipette tips, so that the size of the second gun tip adapter 313 is universal, so that it can adapt to different types of second pipette tips 32 according to usage requirements, and there is no need to replace the second gun tip adapter 313, so as to reduce costs, simplify operations, and improve the compatibility of the pipetting device. It should be noted here that the universal adapter is a conventional structure in the field of pipette tip adapters, which can mainly connect the piston cavity and the pipette tip, and is compatible with the installation of various types of pipette tips, and will not be described in detail in this embodiment.

[0071] like Figure 3 and Figure 4 As shown, the second pipette 30 also includes a second pipette mounting plate 35 and a second pipette drive assembly 33. The second piston cylinder 312 and the second pipette drive assembly 33 are both arranged on the second pipette mounting plate 35 to improve the modularity of the second pipette 30. The second pipette drive assembly 33 is connected to the second piston rod 314 to drive the second piston rod 314 to reciprocate in the second piston chamber to achieve liquid aspiration and liquid discharge.

[0072] In this embodiment, the second pipetting drive assembly 33 includes a second pipetting motor 331, a second pipetting screw 332, and a second pipetting nut 333. The second pipetting motor 331 is fixed to the second pipetting mounting plate 35, the second pipetting screw 332 is rotatably disposed on the second pipetting mounting plate 35, and is transmission-connected to the second pipetting motor 331, the second pipetting nut 333 is sleeved on the second pipetting screw 332 and is threadedly connected to the second pipetting screw 332, and the second pipetting nut 333 is connected to the second piston rod 314. When the second pipetting motor 331 is started, it can drive the second pipetting screw 332 to rotate, thereby driving the second pipetting nut 333 to move along the length direction of the second pipetting screw 332, and the second piston rod 314 is driven to move by the second pipetting nut 333 to achieve pipetting or discharging.

[0073] In this embodiment, the second pipetting nut 333 is connected to each second piston rod 314 respectively to synchronously drive the multiple second piston rods 314 to move, thereby achieving batch pipetting of liquid.

[0074] To prevent the second pipetting nut 333 from getting stuck, a second pipetting guide rail 334 is also provided on the second pipetting mounting plate 35. The second pipetting nut 333 or the second pipetting slider 335 connected to the second pipetting nut 333 is slidably connected to the second pipetting guide rail 334 to guide the second pipetting nut 333 through the second pipetting guide rail 334 to prevent the second pipetting nut 333 from getting stuck due to rotation or other reasons.

[0075] In this embodiment, two second pipetting rails 334 are provided, and the second pipetting screw 332 is located between the two second pipetting rails 334, so that the second pipetting nut 333 is subjected to a more uniform force and has a better guiding effect. In other embodiments, the second pipetting rail 334 can be provided with only one, or three, four or more.

[0076] In other embodiments, the second pipetting drive assembly 33 may include an electric push rod, a pneumatic cylinder, a hydraulic cylinder, or a rack and pinion drive assembly, as long as it can drive the second piston rod 314 to move back and forth.

[0077] In this embodiment, the second pipette 30 further includes a second protective cover 311 , which is disposed on the second pipetting mounting plate 35 , and the second piston cylinder 312 is located in the second protective cover 311 to play a protective role.

[0078] The first pipette 20 includes a first piston cylinder 212, a first piston rod 214 and a first gun tip adapter 213. The first piston cavity is disposed in the first piston cylinder 212, and the first piston rod 214 is slidably disposed in the first piston cavity. The first gun tip adapter 213 has a channel therein, and one end of the first gun tip adapter 213 is connected to the main body of the first piston cylinder 212, and the other end is used for detachably connecting the first liquid transfer tip 22. The first piston rod 214 slides in the first piston cavity and can adjust the effective volume of the first piston cavity, so as to suck the liquid into the first liquid transfer tip 22 or discharge it from the first liquid transfer tip 22.

[0079] In this embodiment, the capacity of the first pipette tip 22 is 1000 μl. In other embodiments, the capacity of the first pipette tip 22 can be 50 μl-1000 μl, such as 50 μl, 70 μl, 100 μl, 125 μl, 150 μl, 175 μl, 200 μl, 225 μl, 250 μl, 275 μl, 300 μl, 325 μl, 350 μl, 375 μl, 400 μl, 425 μl, 450 μl, 50 ... The specific capacity of the first pipette tip 22 can be selected according to needs, such as 475 μl, 500 μl, 525 μl, 550 μl, 575 μl, 600 μl, 625 μl, 650 μl, 675 μl, 700 μl, 725 μl, 750 μl, 875 μl, 900 μl, 925 μl, 950 μl, 975 μl or 1000 μl.

[0080] In other embodiments, the capacity of the pipette tip in the first pipette 20 is different from the capacity of the pipette tip in at least one of the second pipettes 30 to meet diverse needs.

[0081] It should be noted here that the first pipette tip adapter 213 is a universal adapter, so as to replace the first pipette tip 22 of different capacity according to actual needs, thereby improving versatility.

[0082] To facilitate automatic disassembly of the pipette tip, the first pipette 20 and the second pipette 30 further include a linkage assembly, which can cooperate with the pipette drive assembly or the piston rod transmission to push the pipette tip to be disengaged from the pipette body.

[0083] For the convenience of introduction, the linkage component in the second pipette 30 is the second linkage component 34. Figure 2 , Figure 4 and Figure 5As shown, the second linkage assembly 34 includes a second guide rod 341, a second pusher 343 and a second elastic member 342. The second guide rod 341 is arranged in parallel with the second piston rod 314, and the second guide rod 341 is slidably arranged in the second pipette body 31, and the end of the second guide rod 341 away from the second pipette head 32 can abut against the second piston rod 314; the second pusher 343 is arranged at the end of the second guide rod 341 close to the second pipette head 32, and the second pusher 343 can abut against the second pipette head 32, so that under the drive of the second guide rod 341, the second pipette head 32 is pushed downward to realize the disassembly of the second pipette head 32; the second elastic member 342 connects the second guide rod 341 and the second pipette body 31, and the second elastic member 342 is used to drive the second guide rod 341 to move in the direction away from the second pipette head 32, so that the second pusher 343 can be away from the second pipette head 32.

[0084] For the convenience of introduction, the second pipette tip 32 is set at the bottom end of the second pipette body 31 as an example for explanation. When the second pipette tip 32 needs to be automatically disassembled, the second pipette drive assembly 33 drives the second pipette nut 333 downward to drive the second piston rod 314 downward. After the second pipette nut 333 moves down to the specified position, the second pipette nut 333 can abut against the second guide rod 341, pushing the second guide rod 341 to move downward, and the second guide rod 341 will overcome the elastic force of the second elastic member 342, driving the second pusher 343 downward until the second pusher 343 abuts against the second pipette tip 32, and the second pipette tip 32 is disengaged from the second gun head adapter 313.

[0085] When the second pipetting drive assembly 33 drives the second pipetting nut 333 to move upward, the second guide rod 341 drives the second pusher 343 to move upward under the drive of the second elastic member 342 until the second guide rod 341 is reset.

[0086] In this embodiment, a second through hole is provided on the second pusher 343 corresponding to each second gun tip adapter 313, and the second gun tip adapter 313 is inserted into the second through hole. When the second pusher 343 moves downward, the second gun tip adapter 313 moves in the second through hole to provide a guide for the second pusher 343, which is also conducive to ensuring the position accuracy of the second pusher 343 and the second liquid transfer tip 32, ensuring that the second pusher 343 can smoothly abut the second liquid transfer tip 32, thereby pushing the second liquid transfer tip 32 to disengage from the second gun tip adapter 313.

[0087] Optionally, the second pushing member 343 and the second guide rod 341 may be connected by fasteners such as screws and pins.

[0088] Optionally, two second guide rods 341 are provided, and the opposite ends of the second piston cylinder 312 slide through the second guide rods 341. The two second guide rods 341 are connected to the second pushing member 343 to make the second pushing member 343 move more smoothly, thereby improving the disassembly effect of multiple second pipette tips 32.

[0089] like Figure 6 and Figure 7 As shown, the first pipette 20 includes a first pipette mounting plate 25 and a first pipette drive assembly 23. The first piston cylinder 212 and the first pipette drive assembly 23 are both arranged on the first pipette mounting plate 25 to improve the modularity of the first pipette 20. The first pipette drive assembly 23 is connected to the first piston rod 214, and is used to drive the first piston rod 214 to reciprocate in the first piston chamber to achieve liquid aspiration and liquid discharge.

[0090] In this embodiment, the output end of the first liquid transfer driving assembly 23 is connected to the first piston rod 214 to drive the first piston rod 214 to move back and forth in the first piston chamber to achieve liquid transfer or liquid discharge.

[0091] In this embodiment, the first pipetting drive assembly 23 includes a first pipetting motor 231, a first pipetting screw 232 and a first pipetting nut 233. The first pipetting motor 231 is fixed to the first pipetting mounting plate 25, the first pipetting screw 232 is rotatably disposed on the first pipetting mounting plate 25, and is in transmission connection with the first pipetting motor 231, the first pipetting nut 233 is sleeved on the first pipetting screw 232 and is threadedly connected with the first pipetting screw 232, and the first pipetting nut 233 is connected to the first piston rod 214. When the first pipetting motor 231 is started, it can drive the first pipetting screw 232 to rotate, thereby driving the first pipetting nut 233 to move along the length direction of the first pipetting screw 232, and the first piston rod 214 is driven to move by the first pipetting nut 233 to achieve pipetting or discharge.

[0092] To prevent the first pipetting nut 233 from getting stuck, a first pipetting guide rail is also provided on the first pipetting mounting plate 25, and the first pipetting nut 233 is slidably connected to the first pipetting guide rail so as to guide the first pipetting nut 233 through the first pipetting guide rail to prevent the first pipetting nut 233 from getting stuck due to rotation or other reasons.

[0093] In other embodiments, the first pipetting drive assembly 23 may include an electric push rod, a pneumatic cylinder, a hydraulic cylinder, or a rack and pinion drive assembly, as long as it can drive the first piston rod 214 to move back and forth.

[0094] In this embodiment, the first pipette 20 further includes a first protective cover 211 . The first protective cover 211 is disposed on the first pipetting mounting plate 25 . The first piston cylinder 212 is located in the first protective cover 211 to play a protective role.

[0095] The first pipette 20 also includes a first linkage assembly. Figure 6 and Figure 7 As shown, the first linkage assembly includes a first guide rod 241 , a first pushing member 242 and a first elastic member 243 . The first guide rod 241 is arranged in parallel with the first piston rod 214, and the first guide rod 241 is slidably penetrated in the first pipette body 21, and the end of the first guide rod 241 away from the first pipette head 22 can be connected with the first piston rod 214 or the first pipette nut 233; the first pusher 242 is slidably arranged on the first pipette body 21 and is located at the end of the first guide rod 241 close to the first pipette head 22, one end of the first pusher 242 can abut against the first guide rod 241, and the other end of the first pusher 242 can abut against the first pipette head 22, so that under the drive of the first guide rod 241, the first pipette head 22 is pushed downward to realize the disassembly of the first pipette head 22; the first elastic member 243 connects the first pusher 242 and the first pipette body 21, and the first elastic member 243 is used to drive the first pusher 242 to move in the direction away from the first pipette head 22, so that the first pusher 242 can be away from the first pipette head 22.

[0096] For the convenience of introduction, the first pipette tip 22 is set at the bottom end of the first pipette body 21 as an example for explanation. When the first pipette tip 22 needs to be automatically disassembled, the first pipette drive assembly 23 drives the first pipette nut 233 downward to drive the first piston rod 214 downward. After the first pipette nut 233 moves down to the specified position, the first pipette nut 233 can abut against the first guide rod 241, pushing the first guide rod 241 to move downward, and the first guide rod 241 will push the first pusher 242 to overcome the elastic force of the first elastic member 243 and move downward until the first pusher 242 abuts against the first pipette tip 22, and the first pipette tip 22 is disengaged from the first gun head adapter 213.

[0097] When the first pipetting drive assembly 23 drives the first pipetting nut 233 to move upward, the first pipetting nut 233 drives the first guide rod 241 to move upward, and the first pusher 242 moves upward under the drive of the first elastic member 243 until the first pusher 242 is reset.

[0098] In this embodiment, the first pusher 242 is provided with a first through hole corresponding to the first gun tip adapter 213, and the first gun tip adapter 213 is inserted into the first through hole. When the first pusher 242 moves downward, the first gun tip adapter 213 moves in the first through hole to provide guidance for the first pusher 242, which is also conducive to ensuring the position accuracy of the first pusher 242 and the first liquid transfer tip 22, ensuring that the first pusher 242 can smoothly abut against the first liquid transfer tip 22, thereby pushing the first liquid transfer tip 22 to disengage from the first gun tip adapter 213.

[0099] In order to make the stroke of the first guide rod 241 controllable, the first pipette 20 further includes an upper limit member 251 and a lower limit member 252. The upper limit member 251 is arranged on the first pipette nut 233 and can be raised and lowered with the first pipette nut 233. When the first pipette nut 233 abuts against the first guide rod 241, the upper limit member 251 can be triggered. The lower limit member 252 is arranged on the first push member 242, and is triggered when the first push member 242 moves to the lowest position under the push of the first guide rod 241, at which time the first pipette tip 22 can be ensured to be disengaged from the first gun tip adapter 213.

[0100] Optionally, the upper limit member 251 and the lower limit member 252 may be proximity sensors, micro switches, infrared sensors or mechanical limit members.

[0101] Optionally, the second pipette 30 may also include an upper limit member 251 and a lower limit member 252 , and the specific structure may refer to the upper limit member 251 and the lower limit member 252 in the first pipette 20 , as long as the limit position of the second guide rod 341 can be detected.

[0102] In order to facilitate the first pipette 20 and the second pipette 30 to move to the pipetting station as needed, the pipetting device also includes a first lifting mechanism 40 and a second lifting mechanism 50. The first lifting mechanism 40 and the second lifting mechanism 50 are both arranged on the mounting member 10, and the first lifting mechanism 40 is connected to the first pipette 20 for driving the first pipette 20 to rise and fall. The second lifting mechanism 50 is connected to the second pipette 30 for driving the second pipette 30 to rise and fall.

[0103] The first lifting mechanism 40 includes a first lifting motor 42, a first lifting screw 43 and a first lifting nut 44. The mounting member 10 is provided with a first motor seat 41 and a first rotary support seat 46, the first motor seat 41 and the first rotary support seat 46 are arranged opposite to each other, the first lifting motor 42 is arranged on the first motor seat 41, one end of the first lifting screw 43 is transmission-connected to the first lifting motor 42, and the other end of the first lifting screw 43 is rotationally connected to the first rotary support seat 46. The first lifting nut 44 is screw-matched with the first lifting screw, and the first lifting nut 44 is connected to the first liquid transfer mounting plate 25. After the first lifting motor 42 is started, it can drive the first lifting screw 43 to rotate, so that the first lifting nut 44 moves back and forth along the length direction of the first lifting screw 43, thereby driving the first liquid transfer mounting plate 25 to rise and fall.

[0104] In order to make the first pipette 20 move more smoothly, a first lifting guide rail 45 is further provided on the mounting member 10 , and the first lifting nut 44 is slidably connected to the first lifting guide rail 45 to guide the first lifting nut 44 .

[0105] The pipetting device also includes a first position detection member 61, which can be triggered when the first pipette 20 moves to the pipetting position. The first position detection member 61 is communicatively connected with the first lifting mechanism 40 so that the first lifting mechanism 40 stops after the first pipette 20 moves to the pipetting position.

[0106] Optionally, the first position detection member 61 may be a micro switch, a proximity switch or an infrared beam sensor, and the first position detection member 61 may be triggered by the first pipette 20 moved to the pipetting position.

[0107] The second lifting mechanism 50 includes a second lifting motor 52, a second lifting screw 53 and a second lifting nut 54. The mounting member 10 is provided with a second motor seat 51 and a second rotary support seat, the second motor seat 51 and the second rotary support seat are arranged opposite to each other, the second lifting motor 52 is arranged on the second motor seat 51, one end of the second lifting screw 53 is transmission-connected to the second lifting motor 52, and the other end of the second lifting screw 53 is rotationally connected to the second rotary support seat. The second lifting nut 54 is screw-matched with the second lifting screw, and the second lifting nut 54 can be connected to the second liquid transfer mounting plate 35 through the adapter 55. After the second lifting motor 52 is started, it can drive the second lifting screw 53 to rotate, so that the second lifting nut 54 moves back and forth along the length direction of the second lifting screw 53, and then drives the second liquid transfer mounting plate 35 to rise and fall through the adapter 55.

[0108] In order to make the second pipette 30 move more smoothly, a second lifting rail 56 is further provided on the mounting member 10 , and the second lifting nut 54 and / or the adapter 55 are slidably connected to the second lifting rail 56 to guide the second lifting nut 54 .

[0109] The pipetting device also includes a second position detection member 62, which can be triggered when the second pipette 30 moves to the pipetting position. The second position detection member 62 is communicatively connected to the second lifting mechanism 50 so that the second lifting mechanism 50 stops after the second pipette 30 moves to the pipetting position.

[0110] Optionally, the second position detection member 62 may be a micro switch, a proximity switch or an infrared beam sensor, and the second position detection member 62 may be triggered by the second pipette 30 moving to the pipetting position.

[0111] Obviously, the above embodiments of the present invention are merely examples for the purpose of clearly illustrating the present invention, and are not intended to limit the implementation methods of the present invention. For those skilled in the art, various obvious changes, readjustments and substitutions can be made without departing from the scope of protection of the present invention. It is not necessary and impossible to list all implementation methods here. Any modifications, equivalent substitutions and improvements made within the spirit and principles of the present invention shall be included in the scope of protection of the claims of the present invention.

Claims

1. A liquid transfer device, characterized in that: include: Mounting member (10); A first pipette (20), the first pipette (20) being movably arranged on the mounting member (10), the first pipette (20) being provided with a first pipetting channel; a second pipette (30), the second pipette (30) being movably arranged on the mounting member (10), the second pipette (30) being provided with at least two second pipetting channels; The first pipette (20) and the second pipette (30) can be selectively moved to the pipetting station respectively.

2. The liquid transfer device according to claim 1, characterized in that: In the second pipette (30), the volumes of any two of the second pipetting channels are the same, or the volumes of at least two of the second pipetting channels are different; And / or, the volume of the first pipetting channel is different from the volume of at least one of the second pipetting channels.

3. The liquid transfer device according to claim 1, characterized in that: The first pipette (20) and the second pipette (30) both comprise a pipette body and a pipette tip, a piston cavity is formed in the pipette body, the pipette tip is detachably connected to the pipette body, and the pipette tip is connected to the piston cavity to form a pipetting channel.

4. The liquid transfer device according to claim 3, characterized in that: The pipette body comprises a universal adapter, and the universal adapter is detachably connected to the pipette tip, and the universal adapter can be connected to the pipette tips of at least two capacities.

5. The liquid transfer device according to claim 3, characterized in that: The first pipette (20) and the second pipette (30) further include a pipetting drive assembly and a piston rod, wherein the piston rod is disposed in the piston cavity, and the pipetting drive assembly is connected to the piston rod and is used to drive the piston rod to reciprocate in the piston cavity to change the effective volume of the piston cavity; The first pipette (20) and / or the second pipette (30) further comprises a linkage assembly, which can cooperate with the piston rod or the pipetting drive assembly to push the pipetting tip to disengage from the pipette body.

6. The liquid transfer device according to claim 5, characterized in that: The linkage components include: A guide rod, wherein the guide rod is parallel to the piston rod, the guide rod is slidably disposed in the pipette body, and an end of the guide rod facing away from the pipette tip can abut against the piston rod or the pipette drive assembly; A pusher, disposed at one end of the guide rod close to the pipette tip, the pusher being capable of abutting against the pipette tip; An elastic member, connecting the guide rod and the pipette body, the elastic member being used to drive the guide rod to move in a direction away from the pipette tip; Or, the linkage component includes: A guide rod, wherein the guide rod is parallel to the piston rod, the guide rod is slidably disposed in the pipette body, and an end of the guide rod facing away from the pipette tip can abut against the piston rod or the pipette drive assembly; A pusher, slidably disposed in the pipette body, one end of the pusher being able to abut against the guide rod, and the other end being able to abut against the pipette tip; An elastic member connects the pushing member and the pipette body, and the elastic member is used to drive the pushing member to move in a direction away from the pipette tip.

7. The liquid transfer device according to claim 6, characterized in that: In the second pipette (30), the pushing member can abut against each of the pipette tips in the second pipette (30).

8. The liquid transfer device according to any one of claims 1 to 7, characterized in that: The first pipette (20) and the second pipette (30) are both movably mounted on the mounting member (10), and the first pipette (20) and the second pipette (30) can be selectively lifted or lowered respectively.

9. The liquid transfer device according to claim 8, characterized in that: The liquid transfer device also includes: a first lifting mechanism (40), the first lifting mechanism (40) being arranged on the mounting member (10) and connected to the first pipette (20), and being used for driving the first pipette (20) to move up and down; A first position detection member (61), the first position detection member (61) being communicatively connected to the first lifting mechanism (40), and the first position detection member (61) being capable of being triggered by the first pipette (20) located at the pipetting station; And / or, the pipetting device further comprises: A second lifting mechanism (50), the second lifting mechanism (50) is arranged on the mounting member (10) and connected to the second pipette (30), and is used to drive the second pipette (30) to move up and down; A second position detection component (62), the second position detection component (62) is communicatively connected to the second lifting mechanism (50), and the second position detection component (62) can be triggered by the second pipette (30) located at the pipetting station.

10. The liquid transfer device according to any one of claims 1 to 7, characterized in that: The first pipette (20) and the second pipette (30) are both slidably arranged on the mounting member (10), and the first pipette (20) is arranged on one side of the second pipette (30).

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