Water-free cell resuscitation device

By introducing vibration and temperature control mechanisms into anhydrous cell resuscitation device, the problem of cell agglomeration is solved, uniform heating of cells and precise temperature control are achieved, and the resuscitation efficiency and survival rate are improved.

CN222250786UActive Publication Date: 2024-12-27HUAZHONG HEALTH MANAGEMENT (SHANDONG) CO LTD
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Patent Information

Application Number
CN202420961364.5
Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
Filing Date
2024-05-07
Publication Date
2024-12-27
Estimated Expiration
2034-05-07

AI Technical Summary

Technical Problem

Existing anhydrous cell resuscitation devices cannot effectively break cell agglomeration, resulting in damage to cells or incomplete resuscitation during resuscitation.

Method used

An anhydrous cell resuscitation device including a vibration mechanism and a temperature control mechanism is designed. The vibration mechanism breaks cell agglomeration through continuous slight vibration, and the temperature control mechanism achieves precise temperature control to ensure that each cell is uniformly heated.

Benefits of technology

Cell agglomeration is broken through the vibration mechanism, promote uniform dispersion of cells, improve resuscitation efficiency and vitality, and ensure that cells are always at the appropriate temperature through the temperature control mechanism, improve resuscitation efficiency and survival rate, and avoid heat loss and uneven distribution.

✦ Generated by Eureka AI based on patent content.

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Abstract

The utility model provides a water-free type cell resuscitation device, which relates to the technical field of resuscitation devices and comprises a vibration mechanism, the top of the vibration mechanism is fixedly connected with a temperature control mechanism, the vibration mechanism comprises a base, two fixing plates are fixedly mounted at the top of the base, an eccentric shaft is movably inserted between the inner surface walls of the two fixing plates, and the eccentric shaft is fixedly connected with the temperature control mechanism. One side of the outer wall of the eccentric shaft is fixedly connected with a rotation driving motor, and the outer surface wall of the eccentric shaft is movably sleeved with a connecting rod. According to the utility model, under the mutual cooperation of all the components of the vibration mechanism, the cryopreservation tube can generate continuous and slight vibration in the heating recovery process, and the vibration effect is beneficial to breaking the cell agglomeration phenomenon and promoting the cells to be uniformly dispersed in the recovery liquid, so that the recovery efficiency and vitality of the cells are improved; and the heat conduction effect can be enhanced by continuous slight vibration, so that the cells can reach a proper recovery temperature more quickly.
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Description

Technical Field

[0001] The utility model relates to the technical field of resuscitation devices, in particular to a waterless cell resuscitation device. Background Art

[0002] The waterless cell resuscitation device is an advanced medical device designed to achieve rapid and safe cell resuscitation in a waterless manner. In the traditional cell resuscitation process, a water bath or other liquid media is often used for heating, but this method has many potential risks and inconveniences, such as the inability to accurately control temperature and easy contamination. The emergence of the waterless cell resuscitation device effectively solves these problems.

[0003] Since cells may form aggregates during the freezing process, this phenomenon will significantly affect the recovery effect and cell vitality. Aggregated cells are not easy to be heated evenly during the recovery process. Although the existing waterless cell recovery devices can achieve rapid heating and recovery of cells during use, they lack an effective treatment mechanism for cell aggregates and cannot fully break up cell aggregates. It cannot ensure that each cell can be heated evenly, resulting in cell damage or incomplete recovery during the recovery process. Utility Model Content

[0004] The purpose of the utility model is to solve the problem that when the above-mentioned equipment is in use, the waterless cell resuscitation device cannot fully break up cell agglomerations and cannot heat each cell evenly, resulting in cell damage or incomplete resuscitation during the resuscitation process, thereby proposing a waterless cell resuscitation device.

[0005] In order to achieve the above-mentioned purpose, the utility model adopts the following technical scheme: a waterless cell resuscitation device, comprising a vibration mechanism, the top of which is fixedly connected with a temperature control mechanism;

[0006] The cam is provided with a plurality of springs, each of which has a plurality of springs, each of which has a plurality of springs, each of which has a plurality of springs, each of which has a plurality of springs, each of which has a plurality of springs, each of which has a plurality of springs, each of which has a plurality of springs.

[0007] Preferably, a placement plate is fixedly connected between the tops of the four second springs, and the top of the support column is fixedly connected to the bottom of the placement plate, and a plurality of test tube racks are fixedly installed on the top of the placement plate.

[0008] Preferably, the temperature control mechanism comprises an insulation box, a controller is fixedly mounted on one side of the outer wall of the insulation box, and a temperature sensor is fixedly mounted on the inner wall of the insulation box.

[0009] Preferably, a plurality of connecting plates are fixedly installed between the inner surface walls of the heat preservation box, and a circulation pipe is fixedly connected between the tops of the plurality of connecting plates.

[0010] Preferably, the input end of the circulation pipeline is fixedly connected to a water pump, the input end of the water pump is fixedly connected to a water tank, and the output end of the circulation pipeline is fixedly connected to the input end of the water tank.

[0011] Preferably, a heating pipe is fixedly installed on the inner wall of the water tank.

[0012] Preferably, the top of the mounting plate is fixedly connected to the bottom of the insulation box, the top of the mounting plate is fixedly connected to the bottom of the water pump, and the top of the mounting plate is fixedly connected to the bottom of the water tank.

[0013] Compared with the prior art, the advantages and positive effects of the utility model are:

[0014] In the utility model, through the mutual cooperation of the components of the vibration mechanism, the cryopreservation tube can produce continuous and slight vibration during the heating and resuscitation process. This vibration effect helps to break up the cell agglomeration phenomenon and promote the uniform dispersion of cells in the resuscitation solution, thereby improving the resuscitation efficiency and vitality of the cells. In addition, the continuous slight vibration can also enhance the heat conduction effect, so that the cells can reach the appropriate resuscitation temperature more quickly.

[0015] In the utility model, accurate control of the cell recovery temperature is achieved through the mutual cooperation of the various components of the temperature control mechanism, ensuring that the cells are always in the most suitable temperature environment during the recovery process, thereby improving the cell recovery efficiency and survival rate. In addition, the circulation pipeline surrounds multiple placement plates, which not only effectively avoids heat loss and uneven distribution, but also further enhances the heat conduction efficiency. BRIEF DESCRIPTION OF THE DRAWINGS

[0016] Figure 1 The utility model provides a three-dimensional split diagram of the main structure of a waterless cell resuscitation device;

[0017] Figure 2 A three-dimensional diagram of a vibration mechanism in a waterless cell resuscitation device proposed by the utility model;

[0018] Figure 3 The utility model provides a three-dimensional exploded diagram of the structure of the vibration mechanism in a waterless cell resuscitation device;

[0019] Figure 4 The utility model provides a three-dimensional exploded diagram of a temperature control mechanism in a waterless cell resuscitation device.

[0020] Legend:

[0021] 1. Vibration mechanism; 101. Base; 102. Fixed plate; 103. Eccentric shaft; 104. Driving motor; 105. Connecting rod; 106. Movable slot; 107. Movable rod; 108. Mounting seat; 109. Support column; 110. First spring; 111. Support leg; 112. Mounting plate; 113. Limit block; 114. Limit slot; 115. Spring sleeve; 116. Second spring; 117. Placement plate; 118. Test tube rack;

[0022] 2. Temperature control mechanism; 201. Insulation box; 202. Controller; 203. Temperature sensor; 204. Connecting plate; 205. Circulation pipe; 206. Water pump; 207. Water tank; 208. Heating pipe. DETAILED DESCRIPTION

[0023] In order to more clearly understand the above-mentioned purpose, features and advantages of the utility model, the utility model is further described below in conjunction with the accompanying drawings and embodiments. It should be noted that the embodiments of the present application and the features in the embodiments can be combined with each other without conflict.

[0024] In the following description, many specific details are set forth to facilitate a full understanding of the present invention. However, the present invention may also be implemented in other ways than those described herein. Therefore, the present invention is not limited to the specific embodiments of the following disclosure.

[0025] Embodiment 1, as Figure 1-Figure 4 As shown, the utility model provides a waterless cell resuscitation device, comprising a vibration mechanism 1, and a temperature control mechanism 2 is fixedly connected to the top of the vibration mechanism 1;

[0026] The vibration mechanism 1 includes a base 101, two fixed plates 102 are fixedly installed on the top of the base 101, an eccentric shaft 103 is movably inserted between the inner surface walls of the two fixed plates 102, a driving motor 104 is fixedly connected to one side of the outer wall of the eccentric shaft 103, a connecting rod 105 is movably sleeved on the outer wall of the eccentric shaft 103, a movable groove 106 is opened on one side of the outer wall of the connecting rod 105, a movable rod 107 is movably inserted on the inner surface wall of the movable groove 106, a mounting seat 108 is movably sleeved on the outer wall of the movable rod 107, a support column 109 is fixedly installed on the top of the mounting seat 108, and a first spring 110 is movably sleeved on the outer wall of the support column 109. The top of the base 101 is fixed Four supporting legs 111 are fixedly installed, and a mounting plate 112 is fixedly connected between the tops of the four supporting legs 111. A limiting block 113 is fixedly installed on the top of the mounting plate 112. A limiting groove 114 is provided on the top of the limiting block 113, and the support column 109 is movably inserted in the inside of the limiting groove 114. Four spring sleeves 115 are fixedly installed on the top of the mounting plate 112, and the bottom of the inner wall of the four spring sleeves 115 are fixedly connected with a second spring 116. A placement plate 117 is fixedly connected between the tops of the four second springs 116, and the top of the support column 109 is fixedly connected to the bottom of the placement plate 117, and a plurality of test tube racks 118 are fixedly installed on the top of the placement plate 117.

[0027] The effect achieved by the entire embodiment 1 is that the cryopreservation tubes are first placed in the placement grooves opened on the tops of the multiple placement plates 117. Then, during the process of cell heating and recovery, the controller 202 starts the driving motor 104, and the output end of the driving motor 104 drives the eccentric shaft 103 to start to rotate stably. Since the eccentric part of the eccentric shaft 103 is movably sleeved with a connecting rod 105, when the eccentric shaft 103 moves eccentrically, it will effectively drive the connecting rod 105 to move accordingly. The movement of the connecting rod 105 further drives the movement of the mounting seat 108. Since a support column 109 is fixedly installed on the top of the mounting seat 108, and the support column 109 is movably inserted in the limiting groove 114, it is ensured that the movement of the support column 109 is in a stable path. Therefore, through the transmission action of the connecting rod 105, the support column 109 realizes up and down movement on the inner surface wall of the limiting groove 114. The up and down movement of the support column 109 directly drives the placement plate 117 to move up and down. During the movement of the placement plate 117, the first spring 110 and the four second springs 116 are squeezed. The first spring 110 and the four second springs 116 not only provide the necessary elastic restoring force, but also ensure that the movement of the placement plate 117 is smooth and controllable. In this way, the placement plate 117 will continuously vibrate up and down. This vibration effectively breaks the cell agglomeration that may be formed during the freezing process, promotes the uniform dispersion of cells in the resuscitation solution, and the vibration also helps to enhance the heat conduction efficiency, so that the cells can reach a suitable resuscitation temperature faster.

[0028] Embodiment 2, as Figure 2-Figure 4 As shown, the temperature control mechanism 2 includes an insulation box 201, a controller 202 is fixedly installed on one side of the outer wall of the insulation box 201, a temperature sensor 203 is fixedly installed on the inner wall of the insulation box 201, a plurality of connecting plates 204 are fixedly installed between the inner walls of the insulation box 201, a circulation pipe 205 is fixedly connected between the tops of the plurality of connecting plates 204, an input end of the circulation pipe 205 is fixedly connected to a water pump 206, an input end of the water pump 206 is fixedly connected to a water tank 207, and an output end of the circulation pipe 205 is fixedly connected to an input end of the water tank 207, a heating pipe 208 is fixedly installed on the inner wall of the water tank 207, the top of the mounting plate 112 is fixedly connected to the bottom of the insulation box 201, the top of the mounting plate 112 is fixedly connected to the bottom of the water pump 206, and the top of the mounting plate 112 is fixedly connected to the bottom of the water tank 207.

[0029] The effect achieved by the entire embodiment 2 is that a plurality of connecting plates 204 are fixedly installed between the inner surface walls of the insulated box 201, and a circulation pipe 205 is fixedly connected between the tops of the connecting plates 204, and the circulation pipe 205 is cleverly surrounded by a plurality of placement plates 117 to form an effective heat conduction network. The circulation pipe 205 is made of copper or copper alloy. This material has excellent heat conduction performance, so that the temperature can be quickly and evenly distributed in the pipe. In this way, when the heating medium flows in the circulation pipe 205, the heat can be quickly transferred to each placement plate 117, ensuring that each cryopreservation tube can obtain a uniform and sufficient heat supply. Temperature sensor 203, temperature sensor 203 can monitor the temperature changes inside the incubator 201 in real time. Through precise cooperation with the controller 202, the temperature sensor 203 can timely feed back the temperature information to the controller 202. The controller 202 accurately controls the heating power of the heating tube 208 inside the water tank 207 according to the received temperature data. When the temperature is low, the controller 202 will increase the heating power to accelerate the heat generation. When the temperature reaches or exceeds the set value, the controller 202 will reduce the heating power to avoid overheating. Through this intelligent adjustment method, it is ensured that the temperature in the circulation pipe 205 is always maintained within an appropriate range, providing a stable and efficient thermal environment for cell recovery.

[0030] Working principle: After the equipment is powered on, the heating tube 208 is first started through the controller 202 to heat the water inside the water tank 207 to a preset suitable temperature. Then, the water pump 206 is started. The water pump 206 extracts the heated water from the inside of the water tank 207 and pressurizes the heated water to make it flow into the circulation pipe 205. The heated water circulates inside the circulation pipe 205, transfers the heat to the multiple placement plates 117, and then flows back to the water tank 207 through the output end of the circulation pipe 205, thereby forming a closed heating circulation system. The circulation pipe 205 surrounds the multiple placement plates 117 to ensure that the heat can be evenly distributed to each cryopreservation tube. During the heating cycle, the temperature sensor 203 monitors the temperature changes inside the incubator 201 in real time and feeds the data back to the controller 202. The controller 202 maintains the temperature inside the incubator 201 within the set range by accurately controlling the heating power of the heating tube 208 based on the received temperature information, thereby avoiding overheating. Heat damages cells, but also ensures sufficient heat for resuscitation. When the temperature is appropriate, the staff properly places the cryopreserved tubes in special placement slots opened on the tops of multiple placement plates 117. At this time, the controller 202 starts the drive motor 104. The output end of the drive motor 104 drives the eccentric shaft 103 to rotate. Since the eccentric part of the eccentric shaft 103 is movably sleeved with a connecting rod 105, as the eccentric shaft 103 rotates, the connecting rod 105 reciprocates. The movement of the connecting rod 105 further drives the mounting seat 108 to move. The mounting seat 108 drives the support column 109 to move up and down on the inner surface wall of the limiting groove 114. The movement of the support column 109 drives the placement plate 117 to move up and down. The movement of the placement plate 117 will squeeze the first spring 110 and the four second springs 116. The elastic action of the first spring 110 and the four second springs 116 causes the placement plate 117 to vibrate continuously up and down. This vibration promotes the uniform dispersion of cells in the resuscitation fluid, improves the resuscitation effect and cell vitality.

[0031] The above description is only a preferred embodiment of the present invention and does not limit the present invention in other forms. Any technician familiar with the profession may use the technical content disclosed above to change or modify it into an equivalent embodiment with equivalent changes and apply it to other fields. However, any simple modification, equivalent change and modification made to the above embodiment based on the technical essence of the present invention without departing from the content of the technical solution of the present invention still falls within the protection scope of the technical solution of the present invention.

Claims

1. A waterless cell resuscitation device, comprising a vibration mechanism (1), characterized in that: A temperature control mechanism (2) is fixedly connected to the top of the vibration mechanism (1); The vibration mechanism (1) comprises a base (101), two fixed plates (102) are fixedly installed on the top of the base (101), an eccentric shaft (103) is movably inserted between the inner walls of the two fixed plates (102), a driving motor (104) is fixedly connected to one side of the outer wall of the eccentric shaft (103), a connecting rod (105) is movably sleeved on the outer wall of the eccentric shaft (103), a movable groove (106) is opened on one side of the outer wall of the connecting rod (105), a movable rod (107) is movably inserted into the inner wall of the movable groove (106), a mounting seat (108) is movably sleeved on the outer wall of the movable rod (107), and a mounting seat (108) is fixedly installed on the top of the mounting seat (108). A support column (109), wherein an outer wall of the support column (109) is movably sleeved with a first spring (110), four support legs (111) are fixedly mounted on the top of the base (101), a mounting plate (112) is fixedly connected between the tops of the four support legs (111), a limit block (113) is fixedly mounted on the top of the mounting plate (112), a limit slot (114) is provided on the top of the limit block (113), and the support column (109) is movably inserted into the inside of the limit slot (114), four spring sleeves (115) are fixedly mounted on the top of the mounting plate (112), and the bottoms of the inner walls of the four spring sleeves (115) are all fixedly connected with second springs (116).

2. The waterless cell resuscitation device according to claim 1, characterized in that: A placement plate (117) is fixedly connected between the tops of the four second springs (116), and the top of the support column (109) is fixedly connected to the bottom of the placement plate (117), and a plurality of test tube racks (118) are fixedly installed on the top of the placement plate (117).

3. The waterless cell resuscitation device according to claim 2, characterized in that: The temperature control mechanism (2) comprises a heat preservation box (201), a controller (202) is fixedly mounted on one side of an outer wall of the heat preservation box (201), and a temperature sensor (203) is fixedly mounted on an inner wall of the heat preservation box (201).

4. The waterless cell resuscitation device according to claim 3, characterized in that: A plurality of connection plates (204) are fixedly installed between the inner surface walls of the heat preservation box (201), and a circulation pipe (205) is fixedly connected between the tops of the plurality of connection plates (204).

5. The waterless cell resuscitation device according to claim 4, characterized in that: The input end of the circulation pipeline (205) is fixedly connected to a water pump (206), the input end of the water pump (206) is fixedly connected to a water tank (207), and the output end of the circulation pipeline (205) is fixedly connected to the input end of the water tank (207).

6. The waterless cell resuscitation device according to claim 5, characterized in that: A heating pipe (208) is fixedly mounted on the inner surface wall of the water tank (207).

7. The waterless cell resuscitation device according to claim 6, characterized in that: The top of the mounting plate (112) is fixedly connected to the bottom of the heat preservation box (201), the top of the mounting plate (112) is fixedly connected to the bottom of the water pump (206), and the top of the mounting plate (112) is fixedly connected to the bottom of the water tank (207).