Sample application needle drying device

Abstract

The utility model relates to a spotting needle drying device which is used for vacuum drying of spotting needles and comprises a base plate, an air suction connector is arranged on any side face of the base plate, and a through hole communicated with the air suction connector is formed in the middle of the upper surface of the base plate. The flow channel plate is provided with a connecting hole, a main flow channel and four secondary flow channels, the connecting hole is communicated with the through hole, the main flow channel comprises four main flow channels, any ends of the four main flow channels intersect at one point, the intersection point of the four main flow channels is located on the axis of the connecting hole, and the secondary flow channels comprise four secondary flow channels; any ends of the four secondary main flow channels intersect at one point, and the end, away from the connecting hole, of each primary main flow channel communicates with the intersection point of the four secondary main flow channels of one primary flow channel. And the needle plate is provided with a via hole group for accommodating the sample application needle head, the via hole group comprises a plurality of via holes arranged in an array, and each via hole corresponds to the position of one end, far away from the intersection point of the secondary main flow channel, of the primary main flow channel. By arranging the runner plate, the drying efficiency of the spotting needle head is improved.

Description

Technical Field

[0001] The utility model relates to the technical field of sample spotting instruments, in particular to a sample spotting needle drying device. Background Art

[0002] As a pre-treatment device for nucleic acid mass spectrometry, the spotter spots trace samples on the target sheet for use in nucleic acid mass spectrometry analysis.

[0003] In order to avoid contamination, the spotting needle usually needs to be cleaned after use and the spotting needle with residual liquid needs to be dried.

[0004] An existing spotting needle drying device includes a plurality of drying holes, each of which is abutted against a spotting needle to seal the drying hole, a cavity below the drying hole is connected to the plurality of drying holes and a vacuum is drawn in the cavity to extract residual liquid on the spotting needle. This drying device usually only has one exhaust channel, and the drying holes arranged in an array have a certain horizontal area. The exhaust efficiencies of the drying holes are different due to the different distances from the exhaust points of the exhaust channel. After the drying holes closer to the exhaust point are dried, the drying holes farther from the exhaust point may still have residual liquid that needs to be further exhausted, which results in prolonged drying time of the spotting needle and waste of resources.

[0005] Therefore, it is urgent to provide a spotting needle drying device that can improve the drying efficiency of the spotting needle. Utility Model Content

[0006] In order to solve the above problems, the utility model provides a sample spotting needle drying device.

[0007] The above technical objectives of the utility model are achieved through the following technical solutions:

[0008] A spotting needle drying device, used for vacuum drying of spotting needles, comprising:

[0009] A substrate, wherein an air intake connector is provided on any side of the substrate, and a through hole connected to the air intake connector is provided in the middle of the upper surface of the substrate;

[0010] A flow channel plate, the flow channel plate is arranged on the upper surface of the substrate, the flow channel plate is provided with a connecting hole, a main flow channel and four secondary flow channels, the connecting hole is arranged in the middle of the flow channel plate, the connecting hole is connected to the through hole, the main flow channel includes four main flow channels, any ends of the four main flow channels intersect at one point, the intersection point of the four main flow channels is located on the axis of the connecting hole, and the adjacent main flow channels are axially symmetrically arranged, the secondary flow channel includes four secondary flow channels, any ends of the four secondary flow channels intersect at one point, the adjacent secondary flow channels are axially symmetrically arranged, and one end of each main flow channel away from the connecting hole is connected to the intersection point of the four secondary flow channels of one secondary flow channel;

[0011] A needle plate, wherein the needle plate is provided with a via group for accommodating the spotting needles, the via group includes a plurality of vias arranged in an array, the needle plate is arranged on the upper surface of the substrate, the lower surface of the needle plate abuts against the upper surface of the flow channel plate, and each of the vias is arranged at a position corresponding to an end of the secondary main flow channel away from the intersection point of the secondary main flow channel.

[0012] As a further improvement: a circular paving groove for accommodating the spotting needle is provided at one end of the secondary main flow channel away from the intersection of the secondary main flow channel, and the diameter of the circular paving groove is greater than the width of the secondary main flow channel.

[0013] As a further improvement: the flow channel plate is a rectangular plate, the midpoint of the main flow channel is offset in the direction away from the line connecting the two ends of the main flow channel to form an expansion portion and an extension portion, the expansion portion is close to the connecting hole, the extension portion is away from the connecting hole, the extension line of the expansion portion along the length direction intersects with the side wall of the flow channel plate, and the extension line of the extension portion along the length direction is parallel to any pair of opposing side walls of the flow channel plate.

[0014] As a further improvement: the via group includes two via sub-groups, the via sub-group includes six vias, each via sub-group corresponds to two secondary flow channels, and the four ends of the four secondary main flow channels corresponding to the two secondary flow channels of each via sub-group are arranged to intersect in pairs.

[0015] As a further improvement: the needle plate is a rectangular plate, and the four corners of the needle plate extend vertically downward to form a clip-on plate, and a fixing through hole is provided at one end of the clip-on plate away from the needle plate, and four clip-on grooves for the clip-on plate to be clipped are provided on the side wall of the base plate corresponding to the position of the clip-on plate, and a threaded through hole is provided on the groove wall of the clip-on groove corresponding to the position of the fixing through hole, and the needle plate is threadedly connected to the base plate by four bolts.

[0016] As a further improvement: a switch accommodating groove is provided on the upper surface of the substrate, a temperature control switch is provided in the switch accommodating groove, and an annular PI heating film is provided on the upper surface of the substrate, and the annular PI heating film is electrically connected to the temperature control switch.

[0017] As a further improvement: a wire accommodating groove is provided on the upper surface of the substrate, the wire accommodating groove intersects with the switch accommodating groove, and a wire through hole connected to the side wall of the substrate is provided on the side wall of the wire accommodating groove.

[0018] As a further improvement: a mounting block is provided on the side wall of the substrate, and a mounting through hole is provided on the mounting block.

[0019] The utility model has the following beneficial effects: by setting a flow channel plate and setting a main flow channel on the flow channel plate, an air extraction point at a connecting hole located in the middle of the main flow channel can evenly extract air from one end of the four main flow channels away from the connecting hole, and by setting four center points, the secondary flow channels at one end of the four main flow channels away from the connecting hole are respectively connected, and the four secondary flow channels of the secondary flow channels can be evenly extracted by the four main flow channels at one end away from the connecting hole, respectively, so that in the case of only one air extraction point, air can be more evenly extracted from the through holes at different distances from the air extraction point, thereby improving the drying efficiency of the spotting needle, reducing the drying time of the spotting needle, and reducing the waste of resources. BRIEF DESCRIPTION OF THE DRAWINGS

[0020] In order to more clearly illustrate the technical solution of the implementation mode of the utility model, the drawings required for use in the implementation mode will be briefly introduced below. It should be understood that the following drawings only show certain embodiments of the utility model and therefore should not be regarded as limiting the scope. For ordinary technicians in this field, other relevant drawings can be obtained based on these drawings without paying creative work.

[0021] Figure 1 It is a schematic diagram of the overall structure of the utility model;

[0022] Figure 2 It is a structural schematic diagram of the flow channel plate of the utility model;

[0023] Figure 3 It is a schematic diagram of the structure of the substrate, temperature control switch and annular PI heating film of the utility model.

[0024] Reference numerals:

[0025] 1-substrate; 2-flow channel plate; 3-needle plate; 4-temperature control switch; 5-ring PI heating film;

[0026] 11-air suction connector; 12-through hole; 13-card connection slot; 14-wire slot; 15-wire hole; 16-mounting block;

[0027] 21-connecting hole; 22-main flow channel; 23-secondary flow channel;

[0028] 221-main stream;

[0029] 221a- expansion portion; 221b- extension portion;

[0030] 231- secondary main stream;

[0031] 31-through hole; 32-clip board. DETAILED DESCRIPTION

[0032] In order to make the purpose, technical scheme and advantages of the embodiments of the utility model clearer, the technical scheme in the embodiments of the utility model will be clearly and completely described below in conjunction with the drawings in the embodiments of the utility model. Obviously, the described embodiments are part of the embodiments of the utility model, not all of the embodiments. Based on the embodiments in the utility model, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the utility model. Therefore, the following detailed description of the embodiments of the utility model provided in the drawings is not intended to limit the scope of the utility model for which protection is claimed, but merely represents selected embodiments of the utility model.

[0033] In the description of the present invention, the terms "upper", "lower", "above", "both ends" and the like indicate orientations or positional relationships based on the orientations or positional relationships shown in the accompanying drawings, and are only for the convenience of describing the present invention and simplifying the description, and do not indicate or imply that the device or element referred to must have a specific orientation, be constructed and operated in a specific orientation, and therefore should not be understood as a limitation on the present invention.

[0034] In the description of the present invention, the terms "first" and "second" are used for descriptive purposes only and cannot be understood as indicating or implying relative importance or implicitly indicating the number of the indicated technical features. Therefore, the features defined as "first" and "second" may explicitly or implicitly include one or more of the features.

[0035] The following combination Figure 1-3 The utility model is described in further detail.

[0036] Example 1

[0037] Reference Figure 1-3 As shown, this embodiment provides a spotting needle drying device for vacuum drying of spotting needles, comprising:

[0038] A substrate 1, wherein an air intake connector 11 is disposed on any side surface of the substrate 1, and a through hole 12 connected to the air intake connector 11 is disposed in the middle of the upper surface of the substrate 1;

[0039] A flow channel plate 2, the flow channel plate 2 is arranged on the upper surface of the substrate 1, and is provided with a connecting hole 21, a main flow channel 22 and four secondary flow channels 23. The connecting hole 21 is arranged in the middle of the flow channel plate 2, and the connecting hole 21 is connected to the through hole 12. The main flow channel 22 includes four main flow channels 22, and any ends of the four main flow channels 22 intersect at one point, and the intersection point of the four main flow channels 22 is located on the axis of the connecting hole 21, and the adjacent main flow channels 22 are arranged axially symmetrically. The secondary flow channel 23 includes four secondary flow channels 231, and any ends of the four secondary flow channels 231 intersect at one point, and the adjacent secondary flow channels 231 are arranged axially symmetrically, and one end of each main flow channel 22 away from the connecting hole 21 is connected to the intersection point of the four secondary flow channels 231 of the primary flow channel 23;

[0040] The needle plate 3 is provided with a via group for accommodating the spotting needles, and the via group includes a plurality of vias 31 arranged in an array. The needle plate 3 is arranged on the upper surface of the substrate 1, and the lower surface of the needle plate 3 abuts against the upper surface of the flow channel plate 2. Each via 31 is arranged at a position corresponding to an end of a primary main flow channel 231 away from the intersection point of the secondary main flow channel 231.

[0041] In this embodiment, the spotting needle may abut against the sealed via hole 31 to ensure the airtightness of the cavity formed between the main flow channel 22 and the secondary flow channel 23 and the spotting needle.

[0042] In one embodiment, the upper end of the through hole 31 may be chamfered to match the inclined outer peripheral surface of the spotting needle to further improve the airtightness when the spotting needle abuts against the through hole 31 .

[0043] In order to reduce the area of ​​the flow channel plate 2 and simplify the overall structure of the utility model, as a further improvement, a circular clearance groove for accommodating the spotting needle is provided at one end of the secondary main flow channel 231 away from the intersection of the secondary main flow channel 231, and the diameter of the circular clearance groove is greater than the width of the secondary main flow channel 231.

[0044] In order to make the overall structure of the main channel 22 and the secondary channel 23 more compact, as a further improvement, the flow channel plate 2 is a rectangular plate, and the midpoint of the main flow channel 22 is offset in the direction away from the line connecting the two ends of the main flow channel 22 to form an expansion portion 221a and an extension portion 221b, the expansion portion 221a is close to the connecting hole 21, and the extension portion 221b is away from the connecting hole 21, the extension line of the expansion portion 221a along the length direction intersects with the side wall of the flow channel plate 2, and the extension line of the extension portion 221b along the length direction is parallel to any pair of opposing side walls of the flow channel plate 2.

[0045] By providing the expansion portion 221 a , the end of the main flow channel 22 away from the connecting hole 21 can be moved away from the connecting hole 21 with higher efficiency.

[0046] By providing the extension portion 221 b , the intersection point of the four secondary main flow channels 231 of the secondary flow channel 23 can be moved away from the main flow channel 22 at a faster efficiency, thereby providing a space for the secondary main flow channel 231 closest to the connection point.

[0047] In order to facilitate the installation of the needle plate 3 on the base plate 1, as a further improvement, the needle plate 3 is a rectangular plate, and the four corners of the needle plate 3 extend vertically downward to form a clamping plate 32. The clamping plate 32 is provided with a fixing through hole at one end away from the needle plate 3. The side wall of the base plate 1 is provided with four clamping grooves 13 for clamping the clamping plate 32 at a position corresponding to the clamping plate 32. The groove wall of the clamping groove 13 is provided with a threaded through hole 12 at a position corresponding to the fixing through hole. The needle plate 3 is threadedly connected to the base plate 1 by four bolts.

[0048] By respectively arranging the clamping plates 32 at the four corners of the needle plate 3 , the four corners of the needle plate 3 can be fixedly connected to the base plate 1 , thereby ensuring the connection stability of the needle plate 3 on the base plate 1 .

[0049] By setting the card-connecting groove 13 and the card-connecting plate 32, the positioning installation of the needle plate 3 on the base plate 1 is realized by vertically carding the card-connecting plate 32 downwards, and the removal of the needle plate 3 on the base plate 1 is realized by vertically pulling out the card-connecting plate 32 upwards, thereby realizing convenient installation / removal of the needle plate 3 on the base plate 1.

[0050] In order to facilitate the installation of the utility model on other structures, as a further improvement, a mounting block 16 is provided on the side wall of the base plate 1 , and a mounting through hole is provided on the mounting block 16 .

[0051] Example 2

[0052] Reference Figure 2 As shown, in order to adapt to two groups of six-channel spotting needles, this embodiment proposes an improvement based on embodiment 1, the via group includes two groups of via sub-groups, the via sub-group includes six vias 31, each via sub-group corresponds to two secondary channels 23, and the four ends of the four adjacent secondary main channels 231 corresponding to the two secondary channels 23 of each via sub-group are arranged to intersect in pairs.

[0053] When the four ends of the four adjacent sub-main flow channels 231 of the two sub-flow channels 23 corresponding to each via sub-group intersect in pairs, the two intersecting endpoints will be simultaneously subjected to the suction extraction of the endpoints of the two main flow channels 22 away from the connecting hole 21 compared to the endpoints of the other non-intersecting sub-main flow channels 231. This situation will reduce the uniformity of the extraction received by the via 31. Therefore, at this time, the two non-intersecting sub-main flow channels 231 of the four intersecting sub-main flow channels 231 close to the end of the intersection of the four sub-main flow channels can be sealed to ensure that all the vias 31 are evenly extracted.

[0054] Example 3

[0055] Reference Figure 3 As shown, in order to further improve the drying effect of the spotting needle, this embodiment proposes an improvement based on Embodiment 1, a switch accommodating groove is provided on the upper surface of the substrate 1, a temperature control switch 4 is provided in the switch accommodating groove, and an annular PI heating film 5 (polyimide film electric heating film) is provided on the upper surface of the substrate 1, and the annular PI heating film 5 is electrically connected to the temperature control switch 4.

[0056] After vacuum extraction is performed on the spotting needle, liquid may still remain on the spotting needle, so the annular PI heating film 5 is provided to heat and dry the residual liquid. The temperature control switch 4 is provided to control the heating temperature to a predetermined temperature.

[0057] In one embodiment, the annular PI heating film 5 may also be replaced with a PI heating film of other shapes.

[0058] In order to facilitate the accommodation of the internal electrical connection wires of the utility model, as a further improvement, the upper surface of the substrate 1 is provided with a wire accommodating groove 14, which intersects with the switch accommodating groove, and the side wall of the wire accommodating groove 14 is provided with a wire hole 15 connected to the side wall of the substrate 1.

[0059] The wire holes 15 are provided to facilitate the electrical connection wires in the wire accommodating grooves 14 to be led out of the side wall of the substrate 1 .

[0060] The above description is only the preferred implementation of the utility model, and is not intended to limit the utility model. For those skilled in the art, the utility model can have various modifications and changes. Any modification, equivalent replacement, improvement, etc. made within the spirit and principle of the utility model shall be included in the protection scope of the utility model.

Claims

1. A spotting needle drying device, used for vacuum drying of spotting needles, characterized in that: include: A substrate, wherein an air intake connector is provided on any side of the substrate, and a through hole connected to the air intake connector is provided in the middle of the upper surface of the substrate; A flow channel plate, the flow channel plate is arranged on the upper surface of the substrate, the flow channel plate is provided with a connecting hole, a main flow channel and four secondary flow channels, the connecting hole is arranged in the middle of the flow channel plate, the connecting hole is connected to the through hole, the main flow channel includes four main flow channels, any ends of the four main flow channels intersect at one point, the intersection point of the four main flow channels is located on the axis of the connecting hole, and the adjacent main flow channels are axially symmetrically arranged, the secondary flow channel includes four secondary flow channels, any ends of the four secondary flow channels intersect at one point, the adjacent secondary flow channels are axially symmetrically arranged, and one end of each main flow channel away from the connecting hole is connected to the intersection point of the four secondary flow channels of one secondary flow channel; A needle plate, wherein the needle plate is provided with a via group for accommodating the spotting needles, the via group includes a plurality of vias arranged in an array, the needle plate is arranged on the upper surface of the substrate, the lower surface of the needle plate abuts against the upper surface of the flow channel plate, and each of the vias is arranged at a position corresponding to an end of the secondary main flow channel away from the intersection point of the secondary main flow channel.

2. The spotting needle drying device according to claim 1, characterized in that: A circular paving groove for accommodating the spotting needle is provided at one end of the secondary main flow channel away from the intersection of the secondary main flow channel, and the diameter of the circular paving groove is greater than the width of the secondary main flow channel.

3. The spotting needle drying device according to claim 1, characterized in that: The flow channel plate is a rectangular plate, and the midpoint of the main flow channel is offset in a direction away from the line connecting the two ends of the main flow channel to form an expansion portion and an extension portion, the expansion portion is close to the connecting hole, and the extension portion is away from the connecting hole, the extension line of the expansion portion along the length direction intersects with the side wall of the flow channel plate, and the extension line of the extension portion along the length direction is parallel to any pair of opposing side walls of the flow channel plate.

4. The spotting needle drying device according to claim 1, characterized in that: The via group includes two via sub-groups, each via sub-group includes six vias, each via sub-group corresponds to two secondary flow channels, and four ends of four secondary main flow channels adjacent to each other corresponding to the two secondary flow channels of each via sub-group are arranged to intersect in pairs.

5. The spotting needle drying device according to claim 1, characterized in that: The needle plate is a rectangular plate, and the four corners of the needle plate extend vertically downward to form a clamping plate. A fixing through hole is provided at one end of the clamping plate away from the needle plate. The side wall of the base plate is provided with four clamping grooves for clamping the clamping plate at a position corresponding to the clamping plate. The groove wall of the clamping groove is provided with a threaded through hole at a position corresponding to the fixing through hole. The needle plate is threadedly connected to the base plate by four bolts.

6. The spotting needle drying device according to claim 1, characterized in that: A switch accommodating groove is provided on the upper surface of the substrate, a temperature control switch is provided in the switch accommodating groove, and an annular PI heating film is provided on the upper surface of the substrate, and the annular PI heating film is electrically connected to the temperature control switch.

7. The spotting needle drying device according to claim 6, characterized in that: A wire accommodating groove is provided on the upper surface of the substrate, the wire accommodating groove intersects with the switch accommodating groove, and a wire passing hole connected to the side wall of the substrate is provided on the side wall of the wire accommodating groove.

8. The spotting needle drying device according to claim 1, characterized in that: A mounting block is provided on the side wall of the substrate, and a mounting through hole is provided on the mounting block.

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