Film pasting equipment for immunochromatography test paper
By designing a film sticking device including base, channel, block, spring and guide plate, the problem of low and uneven film sticking efficiency of immunochromatography test paper film sticking is solved, and a more efficient and stable film sticking process is achieved, and the detection performance is improved and productivity.
Patent Information
- Application Number
- CN202421137751.3
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- Filing Date
- 2024-05-23
- Publication Date
- 2025-01-10
- Estimated Expiration
- 2034-05-23
AI Technical Summary
The film-patting operation efficiency of existing immunochromatography test strips is low and uneven, which leads to the impact of detection performance and lacks unified standards, affecting production efficiency and benefits.
A film sticking device including a base, channel, block, spring and guide plate is designed. Through the cooperation of the block and spring, the uniform adhesion of the NC film is achieved, and the stability of the film is improved through the shearing mechanism and limiting rod. efficiency.
The efficiency and pass rate of the film are improved, ensuring uniform adhesion of the NC film is avoided, and the stability and production efficiency of the film are enhanced.
Smart Images
Figure CN222329102U_ABST
Abstract
Description
Technical Field
[0001] The utility model relates to the field of preparation of immunochromatographic test papers, in particular to a film-sticking device for immunochromatographic test papers. Background Art
[0002] Immunochromatography is a thin layer chromatography analysis technique. Immunochromatography is to pre-couple known antigens or antibodies to a carrier as a capture line. The sample to be tested flows through the capture line driven by the capillary action of the carrier. If there are corresponding antibodies or antigens in the sample, they can react specifically with the antigens or antibodies on the carrier and stick to the carrier, and use the marker to develop color or emit light to determine whether it contains the test substance or the content of the test substance. For this reason, immunochromatography is not only easy to operate, fast to detect, highly specific, and stable, but also easy to carry. It has been widely used in clinical diagnosis, food safety, drug testing, environmental pollution and other fields. In recent years, the maturity of fluorescent immunochromatography has been significantly improved. Fluorescent immunochromatography is an immunochromatography detection method that uses nano fluorescent particles as immune markers. Fluorescent immunochromatography has excellent detection sensitivity and equipment compatibility, and can accurately give test results, making fluorescent immunochromatography widely used in a variety of fields.
[0003] The core of fluorescent immunochromatography technology lies in the fluorescent immunochromatography reagent strip inside the kit. The preparation process of fluorescent immunochromatography reagent strip includes steps such as fluorescent labeling, antigen or antibody fixation, membrane material preparation, and immunochromatography test strip composition. Among them, the nitrocellulose membrane (NC membrane) is used as a solid phase carrier to carry the detection antibody. In the process of immunochromatography test strip composition, the NC membrane needs to be pasted to the specified position of the polyvinyl chloride base plate (PVC base plate). The NC membrane is required to be flat and uniform during the pasting process, otherwise the wrinkled NC membrane will directly affect the detection performance of the immunochromatography test strip. The composition of the immunochromatography test strip requires the film-sticking personnel to hold the two ends of the NC membrane with both hands to align the pasting position of the NC membrane on the PVC base plate, and then quickly paste the NC membrane on the PVC base plate. To this end, the film-sticking personnel must have good eyesight, light hands, fast movements, and uniform pressure, so as to avoid uneven pasting of the NC membrane, excessive pressure, etc. However, in actual operation, there are still cases where the product film is uneven, uneven, or the film is crushed due to improper operation, which affects the qualified rate of the immunochromatographic test strips. At the same time, although the film-sticking operation is simple, the efficiency of manual film-sticking still needs to be improved. In addition, there is no unified standard for manual film-sticking operation, so the quality of the finished product after film-sticking is uneven, which seriously affects production efficiency and benefits. Summary of the invention
[0004] In view of the deficiencies in the prior art, the utility model provides a film-sticking device for immunochromatographic test paper which is convenient for unified film-sticking operation, improves film-sticking efficiency and qualified rate, and has high film-sticking stability, so as to overcome the defects in the prior art.
[0005] The technical solution adopted by the utility model is: a film-sticking device for immunochromatographic test paper, comprising a base, a first channel and a second channel are respectively opened on the base along the horizontal direction, the first channel is located below the second channel, the first channel and the second channel are connected, a pressure block is arranged in the second channel, a sleeve hole is opened on the top surface of the base along the vertical direction, the sleeve hole is connected with the second channel, a pressure rod is movably sleeved on the sleeve hole, two sides of the pressure rod are respectively passed through the two ends of the sleeve hole, the bottom end of the pressure rod is connected to the pressure block, and the pressure rod above the sleeve hole is sleeved with a first spring. A pressure ball is arranged at the top of the pressure rod, and two sides of the first spring are in contact with the pressure ball and the base respectively; a fixed plate is arranged on one side of the base, and the top surface of the fixed plate and the bottom surface of the first channel are located on the same plane, and a sleeve groove is opened on the top surface of the fixed plate, and a support plate is movably sleeved in the sleeve groove, and the height of the top of the support plate is not lower than the height of the top surface of the first channel, and the side of the support plate close to the base is inclined toward the bottom end of the base, and a second spring is arranged below the other side of the support plate, and the two sides of the second spring are respectively connected to the support plate and the fixed plate.
[0006] Preferably, a shearing mechanism is provided on the fixed plate; the shearing mechanism includes a bracket provided on the fixed plate, a support rod movably mounted on the bracket, a supporting ball provided on the top of the support rod, a third spring mounted on the support rod, and a cutter provided at the bottom end of the support rod, the bottom end of the cutter is at a height not lower than the bottom end of the pressing block, the cutter is located above the second spring, a supporting hole is provided at the top of the bracket, the support rod is mounted in the supporting hole, and both ends of the third spring are respectively connected to the bracket and the supporting ball.
[0007] Preferably, a fixing tube is vertically arranged in the sleeve groove, the fixing tube is located below the second spring, a limiting rod is sleeved in the fixing tube, one end of the limiting rod passes through the fixing tube and is installed on the support plate, the second spring is sleeved on the limiting rod, and both ends of the second spring are respectively installed on the support plate and the fixing tube.
[0008] Preferably, a guide plate is provided on the side of the base away from the fixed plate, the guide plate adopts an inverted N-shaped plate structure, the top surface of the bottom plate of the guide plate and the bottom surface of the first channel are located on the same plane, the two side plates of the guide plate are respectively installed obliquely on the base, and the distance between the two side plates of the guide plate gradually decreases along the direction from the top end of the base toward the bottom end of the base.
[0009] Preferably, a through slot is provided in the middle of the bottom plate of the guide plate, and a placement hole is provided on one end of the base close to the guide plate, and the placement hole and the through slot are connected.
[0010] Preferably, a column is arranged at the top of the base, and a support is horizontally arranged at the top of the column.
[0011] Preferably, the width of the first channel is not less than the width of the second channel.
[0012] The beneficial effects of the utility model are as follows: firstly, the utility model allows the NC film to pass through the second channel below the pressing block, and then places the bottom plate in the first channel. By pressing the pressure ball, the pressing block and the NC film can be driven to move toward the bottom plate set in the first channel, and the NC film is evenly pressed on the bottom plate by the pressing block, so that the NC film can be evenly and accurately pasted on the bottom plate, so that there is no unified standard for film pasting operations. The method improves the efficiency and qualified rate of film pasting, and by pasting the NC film passing through the second channel on the top surface of the support plate, the elastic force of the second spring makes the NC film passing through the second channel located above the first channel, avoiding contact between the NC film and the bottom plate, thereby improving the stability of film pasting.
[0013] Secondly, the utility model can control the cutter to move toward the support plate by pressing the support ball, so as to facilitate the shearing of the NC film placed on the support plate. At the same time, the cutter squeezes the NC films on both sides of the cutter and pastes them on the support plate respectively. With the help of the second spring, the NC film pasted on the inner side of the support plate can be driven to rise and reset. By inserting the bottom plate into the first channel again and pressing the pressure ball, the film pasting operation can be repeated. In addition, the utility model limits the movement of the support plate by setting a fixed tube and a limit rod to improve the stability of the support plate.
[0014] Thirdly, the utility model can guide the bottom plate to be inserted into the first channel by the guide plate, so as to facilitate the placement of the bottom plate. The channel is provided on the guide plate and the placement hole is provided on the base, so as to facilitate the bottom plate to be pushed into the first through groove. Moreover, the utility model can support the NC film roll by the support provided, so as to facilitate repeated film laminating. By limiting the width of the first channel and the width of the second channel, the bottom plate is prevented from entering the second channel, that is, when the bottom plate is inserted into the first channel, the bottom plate and the NC film are prevented from contacting. BRIEF DESCRIPTION OF THE DRAWINGS
[0015] Figure 1 It is a first stereoscopic schematic diagram of the utility model.
[0016] Figure 2 It is a second stereoscopic schematic diagram of the utility model.
[0017] Figure 3 It is a three-dimensional cross-sectional view of the utility model.
[0018] Figure 4It is a schematic diagram of the assembly of the fixing plate and the supporting plate in the utility model. DETAILED DESCRIPTION
[0019] like Figures 1 to 4 As shown, a film-sticking device for immunochromatographic test paper comprises a base 1, on which a first channel 2 and a second channel 3 are respectively opened in the horizontal direction, the first channel 2 is located below the second channel 3, the first channel 2 and the second channel 3 are connected, a pressing block 4 is arranged in the second channel 3, a sleeve hole 5 is opened in the top surface of the base 1 in the vertical direction, the sleeve hole 5 is connected with the second channel 3, a pressing rod 6 is movably sleeved on the sleeve hole 5, both sides of the pressing rod 6 pass through the two ends of the sleeve hole 5 respectively, the bottom end of the pressing rod 6 is connected with the pressing block 4, the pressing rod 6 above the sleeve hole 5 is sleeved with a first spring 7, a pressing ball 8 is arranged at the top end of the pressing rod 6, and both sides of the first spring 7 are in contact with the pressing ball 8 and the base 1 respectively; a fixing plate 9 is arranged on one side of the base 1, the top surface of the fixing plate 9 and the bottom surface of the first channel 2 are located on the same plane, a sleeve groove 10 is opened on the top surface of the fixing plate 9, a supporting plate 11 is movably sleeved in the sleeve groove 10, and the top end of the supporting plate 11 is located at a height not lower than the first channel 2, one side of the support plate 11 close to the base 1 is inclined toward the bottom end of the base 1, and a second spring 12 is arranged below the other side of the support plate 11, and the two sides of the second spring 12 are respectively connected to the support plate 11 and the fixing plate 9, the first channel 2 is used to fit the bottom plate, and the second channel 3 is used to fit the NC film, and the NC film fitted in the second channel 3 is located below the pressing block 4, and by pressing the pressing ball 8, the pressing block 4 and the NC film can be driven to move toward the bottom plate fitted in the first channel 2, so that the NC film is evenly and accurately pasted on the bottom plate; by pasting the NC film passing through the second channel 3 on the top surface of the support plate 11, under the elastic force of the second spring 12, the NC film passing through the second channel 3 is located above the first channel 2, so as to prevent the NC film in the second channel 3 from falling into the first channel 2, that is, in the process of the bottom plate passing through the first channel 2, the NC film and the bottom plate are prevented from contacting, thereby improving the stability of the film.
[0020] In this embodiment, a shearing mechanism is provided on the fixed plate 9; the shearing mechanism includes a bracket 13 provided on the fixed plate 9, a support rod 14 movably mounted on the bracket 13, a support ball 15 provided at the top of the support rod 14, a third spring 16 mounted on the support rod 14, and a cutter 17 provided at the bottom end of the support rod 14, the bottom end of the cutter 17 is located at a height not lower than the bottom end of the pressing block 4, the cutter 17 is located above the second spring 12, a support hole is provided at the top of the bracket 13, the support rod 14 is mounted in the support hole, and the two ends of the third spring 16 are respectively connected to the bracket 13 and the support ball 15 By pressing the support ball 15, the cutter 17 can be driven to move toward the support plate 11, so as to shear the NC film placed on the support plate 11. At the same time, the cutter 17 squeezes the NC films on both sides of the cutter 17 and pastes them on the support plate 11 respectively. With the help of the second spring 12, the support plate 11 is quickly reset, and the support plate 11 is driven to move, and the NC film pasted on the outside of the support plate 11 is torn off to complete the film pasting process, and the NC film pasted on the inside of the support plate 11 is raised and reset, and the bottom plate is inserted into the first channel again, and the pressure ball 8 is pressed to facilitate the film pasting process again. It should be noted that the width of the cutter 17 is not greater than the width of the sleeve groove 10, and the descending cutter 17 is sleeved in the sleeve groove 10.
[0021] Please refer again Figure 4 A fixing tube 18 is vertically arranged in the sleeve groove 10, and the fixing tube 18 is located below the second spring 12. A limiting rod 19 is sleeved in the fixing tube 18, and one end of the limiting rod 19 passing through the fixing tube 18 is installed on the support plate 11. The second spring 12 is sleeved on the limiting rod 19, and the two ends of the second spring 12 are respectively installed on the support plate 11 and the fixing tube 18, thereby limiting the support plate 11 so that the support plate 11 can only move up and down, so as to avoid the bottom plate pulled out by the first channel 2, driving the support plate 11 to move horizontally, thereby improving the stability of the support plate 11 when used.
[0022] In this embodiment, a guide plate 20 is provided on the side of the base 1 away from the fixed plate 9. The guide plate 20 adopts an inverted N-shaped plate structure. The top surface of the bottom plate of the guide plate 20 and the bottom surface of the first channel 2 are located on the same plane. The two side plates of the guide plate 20 are respectively installed obliquely on the base 1. The distance between the two side plates of the guide plate 20 gradually decreases along the direction from the top end of the base 1 toward the bottom end of the base 1, so as to facilitate guiding the bottom plate to be inserted into the first channel 2.
[0023] Please refer again Figure 2 A through slot 21 is provided in the middle of the bottom plate of the guide plate 20 , and a placement hole 22 is provided on one end of the base 1 close to the guide plate 20 . The placement hole 22 is connected to the through slot 21 so as to facilitate pushing the bottom plate into the first through slot 21 .
[0024] In this embodiment, a column 23 is disposed at the top of the base 1, and a support 24 is horizontally disposed at the top of the column 23. By sleeved the NC film roll on the support 24, the NC film roll can be conveniently limited to meet the need of repeated film application.
[0025] Specifically, the width of the first channel 2 is not less than the width of the second channel 3 to prevent the bottom plate from entering the second channel 3, thereby facilitating film application on the bottom plate.
[0026] The method of using this product is as follows: Figures 1 to 4 As shown, first, take out the NC film roll, place one end of the NC film roll in the second channel 3 under the pressing block 4, so that the bonding surface of the NC film is close to the bottom end of the base 1, and the NC film is pushed and pulled to make the NC film pass through the second channel 3 under the pressing block 4, and the NC film passing through the second channel 3 is pasted on the support plate 11, and the elastic force of the second spring 12 is used to drive the NC film passing through the second channel 3 to be located above the first channel 2; then, put the NC film roll on the pillar 24, and slightly rotate the NC film roll so that the NC film in the second channel 3 is subjected to tension, that is, the NC film in the second channel 3 is tightly attached to the bottom surface of the pressing block 4.
[0027] Then, one end of the bottom plate is placed on the guide plate 20, and the bottom plate is guided to the side of the first channel 2 by the guide plate 20. The bottom plate is pushed so that it is inserted into the first channel 2. By pressing the pressure ball 8, the pressure block 4 and the NC membrane can be driven to move toward the bottom plate installed in the first channel 2, so that the NC membrane is adhered to the bottom plate; the pressure ball 8 is released, and the elastic action of the first spring 7 is used to drive the pressure ball 8, the pressure rod 6 and the pressure block 4 to reset.
[0028] Then, tear off the NC film pasted on the support plate 11, and drive the NC film roll to rotate in the opposite direction by pulling the NC film torn off from the support plate 11. At the same time, the bottom plate and NC film brought into the base 1 pass through the base 1, and by pressing the support ball 15, drive the cutter 17 to move toward the support plate 11, thereby shearing the NC film above the support plate 11 to complete the film sticking operation.
[0029] In addition, it should be noted that when the cutter 17 cuts the NC film, the cutter 17 squeezes the NC film on both sides of the cutter 17, so that the NC film on both sides of the cutter 17 is respectively attached to the support plate 11, and the support plate 11 is reset by the second spring 12, and the NC film attached to the outside of the support plate 11 is torn off to complete the film application. At the same time, the NC film attached to the inside of the support plate 11 is raised and reset, so that the bottom plate is inserted into the first channel again, and the pressure ball 8 is pressed, and the film application can be performed again to avoid repeatedly attaching the NC film to the support plate 11, thereby reducing the difficulty of operation.
[0030] In this embodiment, the NC film is passed through the second channel 3 below the pressing block 4, and then the bottom plate is placed in the first channel. By pressing the pressure ball 8, the pressing block 4 and the NC film can be driven to move toward the bottom plate set in the first channel 2. The NC film is evenly pressed on the bottom plate by the pressing block 4, so that the NC film can be evenly and accurately pasted on the bottom plate, so that there is no unified standard for the film pasting operation. The method improves the efficiency and pass rate of the film pasting, and the NC film passing through the second channel 3 is pasted on the top surface of the support plate 11. Under the elastic force of the second spring 12, the NC film passing through the second channel 3 is located above the first channel 2, avoiding contact between the NC film and the bottom plate, thereby improving the stability of the film pasting.
[0031] The embodiments described above are only preferred embodiments of the present invention and are not intended to limit the scope of implementation of the present invention. Therefore, any equivalent changes or modifications made based on the structures, features and principles described in the patent scope of the present invention should be included in the patent application scope of the present invention.
Claims
1. A film-sticking device for immunochromatographic test paper, characterized in that: The invention comprises a base (1), wherein a first channel (2) and a second channel (3) are respectively provided on the base (1) along the horizontal direction, wherein the first channel (2) is located below the second channel (3), wherein the first channel (2) and the second channel (3) are connected, wherein a pressure block (4) is arranged in the second channel (3), wherein a sleeve hole (5) is provided on the top surface of the base (1) along the vertical direction, wherein the sleeve hole (5) is connected to the second channel (3), wherein a pressure rod (6) is movably sleeved on the sleeve hole (5), wherein two sides of the pressure rod (6) respectively pass through two ends of the sleeve hole (5), wherein the bottom end of the pressure rod (6) is connected to the pressure block (4), wherein a first spring (7) is sleeved on the pressure rod (6) above the sleeve hole (5), wherein a pressure ball (8) is arranged on the top end of the pressure rod (6), wherein the first spring (7) is sleeved on the pressure rod (6 ... The two sides of a spring (7) are in contact with the pressure ball (8) and the base (1) respectively; a fixing plate (9) is arranged on one side of the base (1); the top surface of the fixing plate (9) and the bottom surface of the first channel (2) are located on the same plane; a sleeve groove (10) is provided on the top surface of the fixing plate (9); a support plate (11) is movably sleeved in the sleeve groove (10); the top of the support plate (11) is located at a height not lower than the top surface of the first channel (2); the side of the support plate (11) close to the base (1) is inclined toward the bottom end of the base (1); a second spring (12) is arranged below the other side of the support plate (11); the two sides of the second spring (12) are respectively connected to the support plate (11) and the fixing plate (9).
2. The film-sticking device for immunochromatographic test paper according to claim 1, characterized in that: The fixing plate (9) is provided with a shearing mechanism; the shearing mechanism comprises a bracket (13) provided on the fixing plate (9), a support rod (14) movably mounted on the bracket (13), a supporting ball (15) provided at the top end of the support rod (14), a third spring (16) mounted on the support rod (14), and a cutter (17) provided at the bottom end of the support rod (14), wherein the height at which the bottom end of the cutter (17) is located is not lower than the height at which the bottom end of the pressing block (4) is located, the cutter (17) is located above the second spring (12), a supporting hole is provided at the top of the bracket (13), the support rod (14) is mounted in the supporting hole, and the two ends of the third spring (16) are respectively connected to the bracket (13) and the supporting ball (15).
3. The film-sticking device for immunochromatographic test paper according to claim 1, characterized in that: A fixing tube (18) is vertically arranged in the sleeve groove (10). The fixing tube (18) is located below the second spring (12). A limiting rod (19) is sleeved in the fixing tube (18). One end of the limiting rod (19) protruding from the fixing tube (18) is mounted on the support plate (11). The second spring (12) is sleeved on the limiting rod (19). Two ends of the second spring (12) are respectively mounted on the support plate (11) and the fixing tube (18).
4. The film-sticking device for immunochromatographic test paper according to claim 1, characterized in that: A guide plate (20) is provided on a side of the base (1) away from the fixed plate (9); the guide plate (20) adopts an inverted N-shaped plate structure; the top surface of the bottom plate of the guide plate (20) and the bottom surface of the first channel (2) are located on the same plane; two side plates of the guide plate (20) are respectively installed obliquely on the base (1); and the distance between the two side plates of the guide plate (20) gradually decreases in a direction from the top end of the base (1) toward the bottom end of the base (1).
5. The film-sticking device for immunochromatographic test paper according to claim 4, characterized in that: A through slot (21) is provided in the middle of the bottom plate of the guide plate (20), and a placement hole (22) is provided on one end of the base (1) close to the guide plate (20), wherein the placement hole (22) and the through slot (21) are connected.
6. The film-sticking device for immunochromatographic test paper according to claim 1, characterized in that: A column (23) is arranged at the top of the base (1), and a support column (24) is arranged horizontally at the top of the column (23).
7. The film-sticking device for immunochromatographic test paper according to claim 1, characterized in that: The width of the first channel (2) is not less than the width of the second channel (3).