Split type temperature control medical intermediate reaction kettle

Abstract

The utility model discloses a split type temperature control medicine intermediate reaction kettle which comprises a reaction kettle main body and a sealing cover, the sealing cover is arranged at the top of the reaction kettle main body, and a vertically downward motor fixing cover is fixedly arranged on the outer wall of the top of the sealing cover. A rotating shaft is fixedly arranged at the center position, penetrating through the sealing cover, of an output shaft of the motor fixing cover through a coupler, and balls distributed at equal intervals are movably connected to the side wall of the rotating shaft through open holes. The output shaft of the motor drives the rotating shaft to rotate, the rotating shaft drives the rotating sleeve to rotate at a high speed, the output shafts of the two reciprocating push rod motors reciprocate up and down to drive the fixing plate to move, and the fixing plate drives the rotating sleeve to reciprocate up and down in the reaction kettle main body through the bearing. The stirring paddle arranged on the outer wall of the rotating sleeve reciprocates up and down in the reaction kettle main body in the rotating process, so that the medical intermediates with different depths can be fully stirred and mixed.

Description

Technical Field

[0001] The utility model relates to the field of pharmaceutical auxiliary equipment, in particular to a split-type temperature-controlled pharmaceutical intermediate reaction kettle. Background Art

[0002] Pharmaceutical intermediates are mainly used for some chemical raw materials or chemical products in the process of drug synthesis. In the production process of pharmaceutical intermediates, a reactor is needed as a reaction container. The intermediates are made of cyclic compounds such as benzene, naphthalene, anthracene, etc. through sulfonation, alkali fusion, nitration, reduction and other reactions. During the reaction, the intermediates need stirring equipment to mix them. However, the existing stirring equipment has a stirring structure fixed at a specified position in the reactor for stirring. However, the mixing radiation range of the stirring structure is limited, and the mixing effect of the raw materials far away from the stirring structure is insufficient. In order to improve the mixing effect during the reaction of pharmaceutical intermediates, we propose a split temperature-controlled pharmaceutical intermediate reactor. Utility Model Content

[0003] The purpose of the utility model is to provide a split temperature-controlled pharmaceutical intermediate reaction kettle to solve the above-mentioned deficiencies in the technology.

[0004] In order to achieve the above-mentioned purpose, the utility model provides the following technical solutions: a split-type temperature-controlled pharmaceutical intermediate reactor, comprising a reactor body and a sealing cover, the sealing cover is arranged on the top of the reactor body, the top outer wall of the sealing cover is fixedly provided with a motor fixing cover vertically downward, the output shaft of the motor fixing cover passes through the central position of the sealing cover and is fixedly provided with a rotating shaft through a coupling, the side wall of the rotating shaft is movably connected with equidistantly distributed balls through an opening, the outer wall of the rotating shaft is sleeved with a rotating sleeve, the inner wall of the rotating sleeve is provided with equidistantly distributed arc-shaped grooves, the inner wall of the arc-shaped groove and the outer wall of the ball are slidably connected, the outer wall of the rotating sleeve is fixedly provided with equidistantly distributed stirring paddles, the top outer wall of the rotating sleeve is fixedly provided with a bearing, the outer ring of the bearing is fixedly provided with two fixed plates, the bottom outer wall of the sealing cover is fixedly provided with two vertically downward reciprocating push rod motors, and one end of the bottom of the reciprocating push rod motor is fixedly connected to the top outer wall of the fixed plate.

[0005] Preferably, a sealing cover is fixedly provided on the outer wall of the reactor body, an electromagnetic heating coil is sleeved on the inner wall of the sealing cover, and a metal heating lining is fixedly provided on the inner wall of the reactor body. During the operation of the electromagnetic heating coil, the metal heating lining generates heat to heat the pharmaceutical intermediate raw materials in the reactor body.

[0006] Preferably, a feeding pipe is connected to the outer wall on one side of the top of the reactor body through an opening, and a discharge pipe is connected to the outer wall on one side of the bottom of the reactor body through an opening. The feeding pipe is convenient for adding the pharmaceutical intermediate into the reactor body, and the discharge pipe is convenient for discharging the material in the reactor body.

[0007] Preferably, a thermometer is fixedly provided on the outer wall of one end of the bottom of the reactor body, and the detection end of the thermometer is located on the inner wall of the reactor body, so that the temperature inside the reactor body can be easily detected by the thermometer.

[0008] Preferably, the top outer wall of the reactor body is fixed with first fixing plates distributed at equal distances, and the outer wall of the first fixing plate is provided with first fixing holes, and the bottom outer wall of the sealing cover is fixed with second fixing plates distributed at equal distances, and the outer wall of the second fixing plate is provided with second fixing holes distributed at equal distances, and the inner walls of the first fixing holes and the second fixing holes are provided with matching bolts to facilitate fixing the sealing cover to the top of the reactor body.

[0009] Preferably, a motor fixing cover is fixedly provided on the top outer wall of the sealing cover, and the motor is located on the inner wall of the motor fixing cover.

[0010] Preferably, a fixing ring is fixedly provided on the bottom outer wall of the sealing cover, and vertically downward supporting legs are fixedly provided on the bottom outer wall of the fixing ring, so that the utility model can be conveniently placed at a designated position through the supporting legs.

[0011] In the above technical solution, the technical effects and advantages provided by the utility model are:

[0012] The output shaft of the motor drives the rotating shaft to rotate, and the rotating shaft drives the rotating sleeve to rotate at a high speed. The output shafts of the two reciprocating push rod motors reciprocate up and down to drive the fixed plate to move. The fixed plate drives the rotating sleeve to reciprocate up and down in the reactor body through the bearing. The stirring paddle provided on the outer wall of the rotating sleeve reciprocates up and down during the rotation process in the reactor body, which can fully stir and mix pharmaceutical intermediates of different depths, greatly improving the mixing effect of the pharmaceutical intermediates. BRIEF DESCRIPTION OF THE DRAWINGS

[0013] In order to more clearly illustrate the embodiments of the present application or the technical solutions in the prior art, the drawings required for use in the embodiments will be briefly introduced below. Obviously, the drawings described below are only some embodiments recorded in the present utility model. For ordinary technicians in this field, other drawings can also be obtained based on these drawings.

[0014] Figure 1 This is a three-dimensional structural schematic diagram of a split temperature-controlled pharmaceutical intermediate reaction kettle of the utility model;

[0015] Figure 2 This is a schematic diagram of the cutaway structure of the reactor body of a split-type temperature-controlled pharmaceutical intermediate reactor of the utility model;

[0016] Figure 3 This is a schematic diagram of the sealing cover structure of a split-type temperature-controlled pharmaceutical intermediate reactor of the utility model;

[0017] Figure 4 This is a schematic diagram of the rotating shaft structure of a split-type temperature-controlled pharmaceutical intermediate reactor of the utility model;

[0018] Figure 5 The utility model is a schematic diagram of the rotating sleeve structure of a split temperature-controlled pharmaceutical intermediate reactor.

[0019] Description of reference numerals:

[0020] 1 reactor body, 2 sealing cover, 3 sealing cover, 4 electromagnetic heating coil, 5 metal heating lining, 6 feeding pipe, 7 discharge pipe, 8 thermometer, 9 first fixing plate, 10 first fixing hole, 11 second fixing plate, 12 second fixing hole, 13 motor fixing cover, 14 motor, 15 rotating shaft, 16 ball bearing, 17 rotating sleeve, 18 arc slide, 19 bearing, 20 fixing plate, 21 reciprocating push rod motor, 22 stirring paddle, 23 fixing ring, 24 supporting legs. DETAILED DESCRIPTION

[0021] In order to enable those skilled in the art to better understand the technical solution of the present invention, the present invention will be further described in detail below in conjunction with the accompanying drawings.

[0022] Embodiment 1

[0023] Refer to the instruction manual Figure 1-5 A split temperature-controlled pharmaceutical intermediate reactor comprises a reactor body 1 and a sealing cover 2. The sealing cover 2 is arranged on the top of the reactor body 1. A motor fixing cover 13 is fixedly arranged on the top outer wall of the sealing cover 2. The output shaft of the motor fixing cover 13 passes through the central position of the sealing cover 2 and is fixedly provided with a rotating shaft 15 through a coupling. The side wall of the rotating shaft 15 is movably connected with balls 16 distributed at equal distances through openings. A rotating sleeve 17 is sleeved on the outer wall of the rotating shaft 15. The rotating sleeve 17 The inner wall is provided with arc grooves 18 distributed at equal distances, the inner wall of the arc groove 18 is slidably connected to the outer wall of the ball bearing 16, the outer wall of the rotating sleeve 17 is fixedly provided with stirring paddles 22 distributed at equal distances, the top outer wall of the rotating sleeve 17 is fixedly provided with a bearing 19, the outer ring of the bearing 19 is fixedly provided with two fixed plates 20, the bottom outer wall of the sealing cover 2 is fixedly provided with two vertically downward reciprocating push rod motors 21, and the bottom end of the reciprocating push rod motor 21 is fixedly connected to the top outer wall of the fixed plate 20.

[0024] Embodiment 2

[0025] Based on the first embodiment, a feeding pipe 6 is connected to the outer wall of the top side of the reactor body 1 through an opening, and a discharge pipe 7 is connected to the outer wall of the bottom side of the reactor body 1 through an opening. The feeding pipe 6 is used to facilitate the addition of pharmaceutical intermediates into the reactor body 1, and the discharge pipe 7 is used to facilitate the discharge of materials in the reactor body 1. A sealing cover 3 is fixedly provided on the outer wall of the reactor body 1, and an electromagnetic heating coil 4 is sleeved on the inner wall of the sealing cover 3. A metal heating lining 5 is fixedly provided on the inner wall of the reactor body 1. During the operation of the electromagnetic heating coil 4, the metal heating lining 5 generates heat to heat the pharmaceutical intermediate raw materials in the reactor body 1. A thermometer 8 is fixedly provided on the outer wall of one end of the bottom of the reactor body 1, and the detection end of the thermometer 8 is located on the inner wall of the reactor body 1. The temperature inside the reactor body 1 is conveniently detected by the thermometer 8.

[0026] Embodiment 3

[0027] Based on the first embodiment, a motor fixing cover 13 is fixedly arranged on the top outer wall of the sealing cover 2, and the motor 14 is located on the inner wall of the motor fixing cover 13; a first fixing plate 9 is fixedly arranged on the top outer wall of the reactor body 1, and a first fixing hole 10 is opened on the outer wall of the first fixing plate 9; a second fixing plate 11 is fixedly arranged on the bottom outer wall of the sealing cover 2, and a second fixing hole 12 is opened on the outer wall of the second fixing plate 11; matching bolts are provided on the inner walls of the first fixing hole 10 and the second fixing hole 12 to facilitate fixing the sealing cover 2 to the top of the reactor body 1; a fixing ring 23 is fixedly arranged on the bottom outer wall of the sealing cover 3, and a vertical downward supporting leg 24 is fixedly arranged on the bottom outer wall of the fixing ring 23, so that the utility model can be conveniently placed in a designated position through the supporting leg 24.

[0028] Working principle of this utility model:

[0029] Refer to the instruction manual Figure 1-5When the utility model is used, the utility model is placed at a designated position by supporting the legs 24, the pharmaceutical intermediate raw material is added into the reactor body 1 through the feeding pipe 6, the electromagnetic heating coil 4 works to generate heat through the metal heating lining 5, and the pharmaceutical intermediate in the reactor body 1 is heated, and the temperature of the pharmaceutical intermediate is detected by the thermometer 8 provided at the bottom of the reactor body 1. When the pharmaceutical intermediate reaches the designated temperature range, the electromagnetic heating coil 4 stops working, and when the temperature of the pharmaceutical intermediate is lower than the designated temperature, the electromagnetic heating coil 4 continues to work to heat it through the metal heating lining 5, and the pharmaceutical intermediate in the reactor body 1 is controlled, and at this time, the rotating shaft 15 is driven by the output shaft of the motor 14. The rotating shaft 15 is engaged with the arc-shaped slide groove 18 on the inner wall of the rotating sleeve 17 through the ball 16, driving the rotating sleeve 17 to rotate at a high speed. During the rotation of the rotating sleeve 17, the output shafts of the two reciprocating push rod motors 21 move up and down to drive the fixed plate 20 to move. The fixed plate 20 drives the rotating sleeve 17 to move up and down in the reactor body 1 through the bearing 19, so that the stirring paddle 22 provided on the outer wall of the rotating sleeve 17 can move up and down during the rotation of the reactor body 1, and can fully stir and mix the pharmaceutical intermediates of different depths, greatly improving the mixing effect of the pharmaceutical intermediates. After the pharmaceutical intermediates are mixed, the pharmaceutical intermediates in the reactor body 1 are discharged through the discharge pipe 7.

[0030] The above only describes some exemplary embodiments of the present invention by way of illustration. It is undoubted that those skilled in the art can modify the described embodiments in various ways without departing from the spirit and scope of the present invention. Therefore, the above drawings and descriptions are illustrative in nature and should not be construed as limiting the scope of protection of the claims of the present invention.

Claims

1. A split temperature-controlled pharmaceutical intermediate reactor, comprising a reactor body (1) and a sealing cover (2), wherein the sealing cover (2) is arranged on the top of the reactor body (1), characterized in that: A motor fixing cover (13) is fixedly provided on the top outer wall of the sealing cover (2) and extends vertically downward. The output shaft of the motor fixing cover (13) passes through the central position of the sealing cover (2) and is fixedly provided with a rotating shaft (15) through a coupling. The side wall of the rotating shaft (15) is movably connected with balls (16) distributed at equal distances through openings. A rotating sleeve (17) is sleeved on the outer wall of the rotating shaft (15). The inner wall of the rotating sleeve (17) is provided with arc-shaped sliding grooves (18) distributed at equal distances. The arc-shaped sliding grooves (18) are provided on the inner wall of the rotating sleeve (17). The inner wall of the rotating sleeve (18) and the outer wall of the ball (16) are slidably connected, the outer wall of the rotating sleeve (17) is fixedly provided with stirring paddles (22) distributed at equal distances, the top outer wall of the rotating sleeve (17) is fixedly provided with a bearing (19), the outer ring of the bearing (19) is fixedly provided with two fixed plates (20), the bottom outer wall of the sealing cover (2) is fixedly provided with two vertically downward reciprocating push rod motors (21), and the bottom end of the reciprocating push rod motor (21) is fixedly connected to the top outer wall of the fixed plate (20).

2. A split temperature-controlled pharmaceutical intermediate reactor according to claim 1, characterized in that: A sealing cover (3) is fixedly provided on the outer wall of the reactor body (1), an electromagnetic heating coil (4) is sleeved on the inner wall of the sealing cover (3), and a metal heating lining (5) is fixedly provided on the inner wall of the reactor body (1).

3. A split temperature-controlled pharmaceutical intermediate reactor according to claim 1, characterized in that: The outer wall on one side of the top of the reactor body (1) is connected to a feeding pipe (6) through an opening, and the outer wall on one side of the bottom of the reactor body (1) is connected to a discharge pipe (7) through an opening.

4. A split temperature-controlled pharmaceutical intermediate reactor according to claim 1, characterized in that: A thermometer (8) is fixedly provided on the outer wall of one end of the bottom of the reactor body (1), and the detection end of the thermometer (8) is located on the inner wall of the reactor body (1).

5. A split temperature-controlled pharmaceutical intermediate reactor according to claim 1, characterized in that: The top outer wall of the reactor body (1) is fixedly provided with first fixing plates (9) distributed at equal distances, and the outer wall of the first fixing plates (9) is provided with first fixing holes (10); the bottom outer wall of the sealing cover (2) is fixedly provided with second fixing plates (11) distributed at equal distances, and the outer wall of the second fixing plates (11) is provided with second fixing holes (12) distributed at equal distances, and the inner walls of the first fixing holes (10) and the second fixing holes (12) are provided with matching bolts.

6. A split temperature-controlled pharmaceutical intermediate reactor according to claim 1, characterized in that: A motor fixing cover (13) is fixedly provided on the top outer wall of the sealing cover (2), and the motor (14) is located on the inner wall of the motor fixing cover (13).

7. A split temperature-controlled pharmaceutical intermediate reactor according to claim 2, characterized in that: A fixing ring (23) is fixedly provided on the bottom outer wall of the sealing cover (3), and a supporting leg (24) extending vertically downward is fixedly provided on the bottom outer wall of the fixing ring (23).

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