Mouse perfusion device

Abstract

The utility model discloses a mouse perfusion device, which relates to the technical field of medical experiment instruments and comprises a containing disc, a placing plate, an injector and an automatic propelling device. The automatic propelling device comprises a driving device and a mounting base, the injector comprises a needle cylinder and a piston, the mounting base is provided with a first end, a second end and a limiting face, the end, away from the needle cylinder, of the piston is located on the side close to the first end, and the limiting face can limit the needle cylinder to move in the direction away from the first end. An output piece of the driving device can drive one end, away from the needle cylinder, of the piston to move in the direction from the first end to the second end; the containing disc is provided with a containing groove, the containing plate can be fixed in the containing groove, and the side, away from the containing disc, of the containing plate is used for fixing a mouse. Automatic infusion of the injector is achieved through the automatic propelling device, the labor amount of an operator is reduced, the operation difficulty is lowered, and the infusion accuracy and stability are improved.

Description

Technical Field

[0001] The utility model relates to the technical field of medical experimental instruments, in particular to a mouse perfusion device. Background Art

[0002] Laboratory mice are currently the most widely used experimental animals, playing a very important role in exploring the basic functions of genes, the pathogenesis of diseases, and preclinical drug screening. They are currently the most widely used, most versatile, most diverse, and most clearly studied experimental animals. Sampling after cardiac perfusion fixation is an important part of mouse experiments. At present, it is often done by two people, one operating and the other holding a 20ml syringe for injection. The disadvantage is that it requires two people to cooperate, and the injector consumes a lot of physical energy after a long time of injection. Therefore, how to find or improve the perfusion fixation method to reduce the difficulty of operation and save operating costs has become an urgent problem to be solved. Utility Model Content

[0003] The utility model aims to provide a mouse perfusion device to solve the problems existing in the above-mentioned prior art, reduce the difficulty of operation, save the operation cost, and reduce the workload of the operator.

[0004] To achieve the above purpose, the utility model provides the following solutions:

[0005] The utility model provides a mouse perfusion device, comprising a holding tray, a placement plate, a syringe and an automatic propulsion device; the automatic propulsion device comprises a driving device and a mounting seat, the syringe comprises a syringe and a piston, the mounting seat comprises a first end, a second end and a limiting surface, an end of the piston away from the syringe is located on a side close to the first end, the limiting surface can limit the syringe from moving in a direction away from the first end, and an output member of the driving device can drive the end of the piston away from the syringe to move in a direction from the first end to the second end; the holding tray has a holding groove, the placement plate can be fixed in the holding groove, and a side of the placement plate away from the holding tray is used for fixing mice.

[0006] Preferably, the driving device includes a driving motor and a slider, the driving motor is fixedly arranged at the first end, the output shaft of the driving motor is fixedly provided with a threaded rod, the end of the threaded rod away from the driving motor is rotatably connected to the mounting seat, a threaded hole is opened on the slider, the threaded rod is threadedly connected in the threaded hole, the axis of the threaded rod is parallel to the axis of the piston, the end of the slider away from the driving motor can push the piston close to the syringe, and the slider is the output member of the driving device.

[0007] Preferably, the driving device further comprises a controller, and the controller is communicatively connected with the driving motor.

[0008] Preferably, the controller is provided with an adjusting knob for adjusting the rotation speed of the driving motor.

[0009] Preferably, a waste liquid barrel is further included, wherein a discharge port communicating with the containing tank is disposed at the bottom of the containing tray, the discharge port is connected to a discharge pipe, and one end of the discharge pipe away from the containing tray is located in the waste liquid barrel.

[0010] Preferably, an anti-slip layer is fixedly provided on the bottom of the placement board.

[0011] Preferably, a plurality of fixing pins are inserted and fixed on one side of the placement board for fixing the mouse.

[0012] Preferably, it further comprises a connecting needle, which comprises a needle and an extension tube, one end of the extension tube is connected and communicated with one end of the needle, and the other end of the extension tube is connected and communicated with the discharge port of the syringe.

[0013] Preferably, one end of the extension tube away from the needle is threadedly fixedly connected to the discharge port of the syringe.

[0014] Compared with the prior art, the utility model has achieved the following technical effects:

[0015] The mouse perfusion device provided by the utility model realizes automatic perfusion of the syringe by adopting an automatic propulsion device, thereby reducing the operator's workload and the difficulty of operation, and utilizes a mechanical propulsion method to replace a manual propulsion method, thereby saving operation costs and improving perfusion accuracy and stability. Furthermore, the mouse is fixed on a placement plate on a holding tray, and waste liquid generated during the injection process can directly fall into the holding tray for easy centralized collection. BRIEF DESCRIPTION OF THE DRAWINGS

[0016] In order to more clearly illustrate the embodiments of the utility model or the technical solutions in the prior art, the drawings required for use in the embodiments will be briefly introduced below. Obviously, the drawings described below are only some embodiments of the utility model. For ordinary technicians in this field, other drawings can be obtained based on these drawings without paying creative work.

[0017] Figure 1 This is a schematic diagram of the overall structure of the mouse perfusion device provided by the utility model;

[0018] Figure 2 This is a schematic diagram of the structure of a driving device in the mouse perfusion device provided by the utility model.

[0019] In the picture: 100-mouse perfusion device;

[0020] 10- serving tray; 11- discharge port; 12- discharge pipe; 13- waste liquid bucket;

[0021] 20-placement plate; 21-fixing needle;

[0022] 30-syringe; 31-syringe barrel; 311-protruding structure; 32-piston; 33-connecting needle; 331-extension tube; 332-needle;

[0023] 40-automatic propulsion device; 41-driving motor; 42-sliding block; 43-mounting seat; 431-first end; 432-second end; 433-limiting surface; 434-placing groove; 435-clamping groove; 436-taking groove; 44-threaded rod; 45-guide rod;

[0024] 50-Controller. DETAILED DESCRIPTION

[0025] The following will be combined with the drawings in the embodiments of the utility model to clearly and completely describe the technical solutions in the embodiments of the utility model. Obviously, the described embodiments are only part of the embodiments of the utility model, not all of the embodiments. Based on the embodiments in the utility model, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the utility model.

[0026] The utility model aims to provide a mouse perfusion device to solve the problems existing in the prior art, reduce the difficulty of operation, save the operation cost, and reduce the workload of the operator.

[0027] In order to make the above-mentioned purposes, features and advantages of the present invention more obvious and easy to understand, the present invention is further described in detail below in conjunction with the accompanying drawings and specific implementation methods.

[0028] Embodiment 1

[0029] This embodiment provides a mouse perfusion device 100, such as Figure 1 and Figure 2As shown, it includes a holding tray 10, a placement plate 20, a syringe 30 and an automatic propulsion device 40; the automatic propulsion device 40 includes a driving device and a mounting seat 43, the syringe 30 includes a syringe 31 and a piston 32, the mounting seat 43 has a first end 431, a second end 432 and a limiting surface 433, the end of the piston 32 away from the syringe 31 is located on the side close to the first end 431, the limiting surface 433 can limit the syringe 31 from moving in a direction away from the first end 431, and the output member of the driving device can drive the end of the piston 32 away from the syringe 31 to move in a direction from the first end 431 to the second end 432; the holding tray 10 has a holding groove, the placement plate 20 can be fixed in the holding groove, and the side of the placement plate 20 away from the holding tray 10 is used to fix the mouse. By adopting the automatic propulsion device 40 to realize automatic perfusion of the syringe 30, the operator's workload is reduced, the operating difficulty is reduced, the mechanical propulsion method is used instead of the manual propulsion method, the operating cost is saved, the perfusion accuracy and stability are improved, and the mouse is fixed on the placement plate 20 on the holding tray 10, and the waste liquid generated during the injection process can fall directly into the holding tray 10 for easy centralized collection.

[0030] Specifically, a placement groove 434 may be further provided at the second end 432 of the mounting seat 43 for placing the syringe barrel 31 of the syringe 30 to facilitate fixing the syringe barrel 31 of the syringe 30 , and an extension direction of the placement groove 434 is parallel to or coincides with a moving direction of the piston 32 .

[0031] Specifically, the syringe 31 is transparent, and a scale is provided on the outer wall of the syringe 31 .

[0032] Among the optional solutions of this embodiment, it is more preferred that Figure 1 and Figure 2 As shown, the driving device includes a driving motor 41 and a slider 42. The driving motor 41 is fixedly arranged at the first end 431. The output shaft of the driving motor 41 is fixedly provided with a threaded rod 44. The end of the threaded rod 44 away from the driving motor 41 is rotatably connected to the mounting seat 43. A threaded hole is opened on the slider 42. The threaded rod 44 is threadedly connected in the threaded hole. The axis of the threaded rod 44 is parallel to the axis of the piston 32. The end of the slider 42 away from the driving motor 41 can push the piston 32 close to the syringe 31. The slider 42 is the output component of the driving device.

[0033] Specifically, the syringe 31 can be fixed in the placement groove 434. The specific fixing method can be that the syringe 31 is clamped in the placement groove 434, or the placement groove 434 is provided with a clamping groove 435 for fixing the protruding structure 311 on the side wall of the syringe 21 away from its discharge port. At this time, the slider 42 can be fixedly connected to the end of the piston 32 away from the syringe 31, so that the slider 42 can drive the piston 32 to move forward or backward relative to the syringe 31, thereby realizing functions such as injection or extraction.

[0034] Specifically, a taking groove 436 connected to the placement groove 434 is provided to facilitate the operator to take the syringe 31 out of the placement groove 434 .

[0035] Specifically, Figure 1 and Figure 2 As shown, at least one guide rod 45 is fixedly disposed on the mounting seat 43 , and each guide rod 45 is parallel to the axis of the threaded rod 44 . The slider 42 is provided with at least one through hole, and each through hole is provided with a guide rod 45 .

[0036] Among the optional solutions of this embodiment, it is more preferred that Figure 1 As shown, the driving device further includes a controller 50, and the controller 50 is in communication connection with the driving motor 41. The operator can control the opening and closing of the driving motor 41 through the controller 50, which reduces the labor intensity of the operator and facilitates control.

[0037] Specifically, the controller 50 can be connected to an external power source.

[0038] In the optional solution of this embodiment, preferably, the controller 50 is provided with an adjusting knob for adjusting the speed of the driving motor 41. The operator can control the injection speed of the syringe 30 by adjusting the knob to meet different injection requirements.

[0039] Among the optional solutions of this embodiment, it is more preferred that Figure 1 As shown, the mouse perfusion device 100 also includes a waste liquid barrel 13, a discharge port 11 connected to the receiving tank is provided at the bottom of the receiving tray 10, and the discharge port 11 is connected to a discharge pipe 12, and one end of the discharge pipe 12 away from the receiving tray 10 is located in the waste liquid barrel 13. It is convenient for automatic discharge and centralized collection of waste liquid.

[0040] Specifically, the bottom surface of the containing tank can be set as an inclined surface to facilitate the automatic discharge of waste liquid, and the discharge port 11 is set at the bottom of the containing tank to achieve automatic discharge.

[0041] In the optional solution of this embodiment, it is more preferred that an anti-skid layer is fixedly arranged at the bottom of the placement plate 20. The anti-skid layer can ensure the fixing effect of the placement plate 20 in the containing groove.

[0042] Specifically, the anti-slip layer may be formed of a rubber layer.

[0043] Specifically, in addition to the anti-slip layer being fixedly provided at the bottom of the placement plate 20, at least one suction cup may also be used to ensure the fixing effect.

[0044] Among the optional solutions of this embodiment, it is more preferred that Figure 1 As shown, a plurality of fixing pins 21 are inserted and fixed on one side of the placement board 20 for fixing mice.

[0045] Specifically, the fixing pins 21 facilitate the fixation of mice, and the placement board 20 is made of a cork board, which can facilitate the insertion and fixation of the fixing pins 21, and can also make the fixing pins 21 directly fixed on the placement board 20 when not in use, thereby improving the fixation speed of mice.

[0046] Among the optional solutions of this embodiment, it is more preferred that Figure 1 and Figure 2 As shown, the mouse perfusion device 100 further includes a connecting needle 33, which includes a needle 332 and an extension tube 331, one end of the extension tube 331 is connected and communicated with one end of the needle 332, and the other end of the extension tube 331 is connected and communicated with the discharge port of the syringe 31. The setting of the extension tube 331 can meet the operator's need to be inserted at different positions on the mouse body without moving the position of the syringe 30.

[0047] In the optional scheme of this embodiment, it is more preferred that the end of the extension tube 331 away from the needle 332 is threadedly fixedly connected to the discharge port of the syringe 31. The threaded fixed connection can prevent the extension tube 331 from being separated from the syringe 31 due to excessive injection pressure, thereby ensuring injection stability.

[0048] The utility model uses specific examples to illustrate the principle and implementation of the utility model. The above examples are only used to help understand the method and core idea of ​​the utility model. At the same time, for those skilled in the art, according to the idea of ​​the utility model, there will be changes in the specific implementation and application scope. In summary, the content of this specification should not be understood as limiting the utility model.

Claims

1. A mouse perfusion device, characterized in that: Includes a holding tray, placement plate, syringe, and automatic advancement device; The automatic propulsion device comprises a driving device and a mounting seat, the syringe comprises a syringe and a piston, the mounting seat has a first end, a second end and a limiting surface, the end of the piston away from the syringe is located on a side close to the first end, the limiting surface can limit the syringe from moving in a direction away from the first end, and the output member of the driving device can drive the end of the piston away from the syringe to move in a direction from the first end to the second end; The holding tray has a holding groove, the placement plate can be fixed in the holding groove, and the side of the placement plate away from the holding tray is used for fixing mice.

2. The mouse perfusion device according to claim 1, characterized in that: The driving device includes a driving motor and a slider. The driving motor is fixedly arranged at the first end. A threaded rod is fixedly arranged on the output shaft of the driving motor. An end of the threaded rod away from the driving motor is rotatably connected to the mounting seat. A threaded hole is provided on the slider. The threaded rod is threadedly connected in the threaded hole. The axis of the threaded rod is parallel to the axis of the piston. The end of the slider away from the driving motor can push the piston close to the syringe. The slider is the output component of the driving device.

3. The mouse perfusion device according to claim 2, characterized in that: The driving device further includes a controller, which is communicatively connected with the driving motor.

4. The mouse perfusion device according to claim 3, characterized in that: The controller is provided with an adjusting knob for adjusting the rotation speed of the driving motor.

5. The mouse perfusion device according to claim 1, characterized in that: It also includes a waste liquid barrel, wherein a discharge port connected to the containing tank is arranged at the bottom of the containing tray, and a discharge pipe is connected to the discharge port, and an end of the discharge pipe away from the containing tray is located in the waste liquid barrel.

6. The mouse perfusion device according to claim 1, characterized in that: An anti-skid layer is also fixedly arranged on the bottom of the placement board.

7. The mouse perfusion device according to claim 1, characterized in that: The placement board is used to fix the mouse and one side thereof is plugged and fixed with a plurality of fixing pins.

8. The mouse perfusion device according to claim 1, characterized in that: It also includes a connecting needle, which includes a needle and an extension tube, one end of the extension tube is connected and communicated with one end of the needle, and the other end of the extension tube is connected and communicated with the discharge port of the syringe.

9. The mouse perfusion device according to claim 8, characterized in that: One end of the extension tube away from the needle is threadedly fixedly connected to the discharge port of the syringe.

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