Medicament sample adding and extracting device for nucleic acid detection

Abstract

The utility model relates to the technical field of detection and analysis equipment, and discloses a nucleic acid detection medicament sample adding and extracting device which comprises a placing table, a sampling plate is arranged at the top of the placing table, a first motor is fixedly connected to the left side of the placing table, and the output end of the first motor is fixedly connected with a lead screw; a guide column is fixedly connected to the right side of the placement table, a nut pair is in threaded connection with the exterior of the lead screw, a lifting assembly is arranged at the top of the nut pair, a lifting assembly is further arranged outside the guide column, supporting plates are connected to the tops of the two lifting assemblies, and three through holes are formed in each supporting plate in a penetrating mode; a sampling bottle is arranged in the through hole, and a liquid outlet pipe is fixedly connected to the bottom of the sampling bottle. According to the utility model, through mutual cooperation of the screw rod, the nut pair, the moving block, the placing groove, the air cylinder and the lifting column, the lifting assembly can drive the supporting plate and the sampling bottle on the supporting plate to carry out lifting adjustment, so that the efficiency is improved.

Description

Technical Field

[0001] The utility model relates to the technical field of detection and analysis equipment, in particular to a drug sample adding and extracting device for nucleic acid detection. Background Art

[0002] Nucleic acid testing is to collect samples such as human throat swabs, analyze the RNA gene sequence of the virus under laboratory conditions, and use PCR amplification methods to perform clinical etiology diagnosis. At present, nucleic acid testing is the most effective detection method for early determination of whether a patient is infected with the virus, early detection, and early treatment. In the prior art, the nucleic acid test swab sampling process uses a swab like a cotton swab to wipe the pharynx and tonsils, or the secretions around the nasal cavity. After the throat swab is taken, it is placed in a tube with a preservation solution and then taken to the laboratory for testing.

[0003] After searching, the existing Chinese patent announcement number is: CN217052227U, which provides a drug sampling and extraction device for nucleic acid detection. The patent squeezes out the sample liquid in the bottle by squeezing the air bag. Compared with using a pipette for pipetting, squeezing it out from the air bag is more convenient and quick. The support plate and the sampling plate are placed on the lifting shaft. The lifting shaft can raise the sampling plate to facilitate the liquid in the lower liquid outlet tube to leak out on the sampling hole to realize the sampling operation. The sampling plate is magnetically connected to the lower connecting plate of the support plate through the upper connecting plate, which is convenient for disassembly and stable placement.

[0004] Although the above patent is more convenient and quicker than using a pipette to transfer liquid by squeezing it out from the air bag, the above-mentioned nucleic acid detection drug sampling and extraction device still has the following problems: the sampling bottle cannot be fixed, which may cause the sampling bottle to loosen during the sampling process, affecting the extraction effect.

[0005] In view of the above problems, a nucleic acid detection reagent sampling and extraction device is proposed. Utility Model Content

[0006] The utility model aims to provide a nucleic acid detection reagent sampling and extraction device, which solves the problem in the background technology that the sampling bottle cannot be fixed, which may cause the sampling bottle to loosen during the sampling process.

[0007] To achieve the above-mentioned purpose, the utility model provides the following technical solutions: a drug sampling and extraction device for nucleic acid detection, comprising a placing table, a sampling plate is arranged on the top of the placing table, a first motor is fixedly connected to the left side of the placing table, a screw rod is fixedly connected to the output end of the first motor, a guide column is fixedly connected to the right side of the placing table, a nut pair is threadedly connected to the outside of the screw rod, a lifting assembly is arranged on the top of the nut pair, a lifting assembly is also arranged on the outside of the guide column, two lifting assemblies are connected to the top of a support plate, three through holes are penetrated and opened in the support plate, a sampling bottle is arranged in the through hole, a liquid outlet pipe is fixedly connected to the bottom of the sampling bottle, a second motor is fixedly connected to the left side of the support plate, a bidirectional threaded rod is fixedly connected to the output end of the second motor, a moving plate is threadedly connected to the outside of both sides of the bidirectional threaded rod, a groove block is fixedly connected to the opposite side of the two moving plates, and a clamping block is slidably connected in the groove block.

[0008] By adopting the above technical solution, the bidirectional threaded rod drives the two movable plates to move relative to each other, and the two sides of the sampling bottle are fixed and clamped by the clamping block to prevent the sampling bottle from loosening during the sample addition and extraction process. The spring expansion and contraction can drive the clamping block to expand and contract in the groove of the groove block, thereby protecting the outer wall of the sampling bottle.

[0009] As a further description of the above technical solution: the lifting assembly includes a moving block, the bottom of the moving block on the left side is fixedly connected to the nut pair, the moving block on the right side penetrates and is slidably connected to the outside of the guide column, and a placement groove is opened on the top of the two moving blocks, a cylinder is fixedly connected in the placement groove, the output end of the cylinder is fixedly connected to the lifting column, and the top of the lifting column is fixedly connected to the support plate.

[0010] By adopting the above technical solution, the cylinder can move the lifting component and the support plate above it, and cooperate with the lifting component to drive the support plate and the sampling bottle on the support plate to be raised and lowered.

[0011] As a further description of the above technical solution: a solenoid valve is arranged outside the liquid outlet pipe.

[0012] By adopting the above technical solution, the outflow of liquid in the sampling bottle can be controlled by the solenoid valve.

[0013] As a further description of the above technical solution: a guide rod passes through and is slidably connected to the left end of the movable plate, and both ends of the guide rod are fixedly connected to the support plate.

[0014] By adopting the above technical solution, the guide rod plays a role in limiting the movable plate.

[0015] As a further description of the above technical solution: three springs are fixedly connected in the groove block, and the other end of the spring is fixedly connected to the clamping block.

[0016] By adopting the above technical solution, the expansion and contraction of the spring can drive the clamping block to expand and contract in the groove of the groove block.

[0017] As a further description of the above technical solution: the clamping block is arranged on the outside of the sampling bottle.

[0018] By adopting the above technical solution, the outer wall of the sampling bottle can be clamped by the clamping block.

[0019] As a further description of the above technical solution: the bottom of the lifting column is arranged in the placement groove, and the outer part of the lifting column is slidably connected with the inner wall of the placement groove.

[0020] By adopting the above technical solution, the lifting column can be lifted and lowered in the placement groove.

[0021] Compared with the prior art, the beneficial effects of the utility model are as follows:

[0022] 1. The utility model provides a nucleic acid detection reagent sampling and extraction device. First, the second motor, the two-way threaded rod, the movable plate, the groove block, the spring, the clamp block, the guide rod and the support plate work in coordination with each other. The two-way threaded rod drives the two movable plates to move relative to each other, and the two sides of the sampling bottle are fixed and clamped by the clamp block to prevent the sampling bottle from loosening during the sampling and extraction process. The spring can drive the clamp block to expand and contract in the groove of the groove block to protect the outer wall of the sampling bottle.

[0023] 2. The utility model provides a drug sampling and extraction device for nucleic acid detection. Through the cooperation of a first motor, a screw rod, a nut pair, a moving block, a placement slot, a cylinder and a lifting column, the screw rod can drive the lifting assembly and the support plate above to move, and the lifting assembly can drive the support plate and the sampling bottle on the support plate to be raised and lowered to improve efficiency. BRIEF DESCRIPTION OF THE DRAWINGS

[0024] Figure 1 It is a schematic diagram of the overall structure of the utility model;

[0025] Figure 2 It is an exploded schematic diagram of the overall structure of the utility model;

[0026] Figure 3 It is an exploded schematic diagram of the movable plate structure of the utility model.

[0027] In the figure: 1. placement table; 2. sampling plate; 3. first motor; 4. screw rod; 5. guide column; 6. moving block; 7. placement slot; 8. cylinder; 9. lifting column; 10. support plate; 11. nut pair; 12. through hole; 13. sampling bottle; 14. liquid outlet pipe; 15. solenoid valve; 16. second motor; 17. bidirectional threaded rod; 18. moving plate; 19. guide rod; 20. groove block; 21. spring; 22. clamping block. DETAILED DESCRIPTION

[0028] The following will refer to the drawings in the embodiments of the utility model to clearly and completely describe the technical solutions in the embodiments of the utility model. Obviously, the described embodiments are only part of the embodiments of the utility model, not all of the embodiments. Based on the embodiments of the utility model, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the utility model.

[0029] In order to further understand the content of the utility model, the utility model is described in detail with reference to the accompanying drawings.

[0030] Reference Figure 1 , Figure 2 and Figure 3 The utility model is a nucleic acid detection agent sample extraction device, comprising a placement table 1, a sampling plate 2 is arranged on the top of the placement table 1, a sampling slot (not marked in the figure) is arranged on the sampling plate 2, a first motor 3 is fixedly connected to the left side of the placement table 1, a screw rod 4 is fixedly connected to the output end of the first motor 3, and the screw rod 4 is driven to rotate by the first motor 3, a guide column 5 is fixedly connected to the right side of the placement table 1, the guide column 5 is fixed on the extended plate of the placement table 1, a nut pair 11 is threadedly connected to the outside of the screw rod 4, a lifting component is arranged on the top of the nut pair 11, a lifting component is also arranged on the outside of the guide column 5, and the tops of the two lifting components are connected to support A support plate 10 is provided with three through holes 12 therein, which are convenient for installing a sampling bottle 13. A sampling bottle 13 is arranged in the through hole 12, and a liquid outlet pipe 14 is fixedly connected to the bottom of the sampling bottle 13. A second motor 16 is fixedly connected to the left side of the support plate 10, and a bidirectional threaded rod 17 is fixedly connected to the output end of the second motor 16. The bidirectional threaded rod 17 is driven to rotate by the second motor 16. Moving plates 18 are threadedly connected to the outside of the two sides of the bidirectional threaded rod 17. A groove block 20 is fixedly connected to the opposite side of the two moving plates 18. A clamping block 22 is slidably connected to the groove block 20, and an anti-slip strip is arranged on the outside of the clamping block 22.

[0031] Reference Figure 2The lifting assembly includes a moving block 6, the bottom of the left moving block 6 is fixedly connected to the nut pair 11, the right moving block 6 penetrates and is slidably connected to the outside of the guide column 5, and a placement groove 7 is opened on the top of the two moving blocks 6. A cylinder 8 is fixedly connected in the placement groove 7, and a lifting column 9 is fixedly connected to the output end of the cylinder 8. The top of the lifting column 9 is fixedly connected to the support plate 10, and the bottom of the lifting column 9 is arranged in the placement groove 7, and the outside of the lifting column 9 is slidably connected to the inner wall of the placement groove 7. The screw rod 4 can drive the lifting assembly and the support plate 10 above to move, and the lifting assembly can drive the support plate 10 and the sampling bottle 13 on the support plate 10 to be lifted and lowered to improve efficiency.

[0032] Reference Figure 2 and Figure 3 A solenoid valve 15 is arranged outside the liquid outlet pipe 14, and the solenoid valve 15 can control the outflow of liquid in the sampling bottle 13. A guide rod 19 is penetrated and slidably connected at the left end of the movable plate 18. Both ends of the guide rod 19 are fixedly connected to the support plate 10. The guide rod 19 serves to limit the movable plate 18. Three springs 21 are fixedly connected in the groove block 20. The other end of the spring 21 is fixedly connected to the clamping block 22. The expansion and contraction of the spring 21 can drive the clamping block 22 to expand and contract in the groove of the groove block 20. The clamping block 22 is arranged on the outside of the sampling bottle 13.

[0033] Working principle: During operation, the sampling bottle 13 filled with the specimen liquid is placed in the through hole 12 of the support plate 10, and then the second motor 16 is started to drive the bidirectional threaded rod 17 to rotate, and the two movable plates 18 are driven to move relative to each other along the guide rod 19 through the bidirectional threaded rod 17, and the clamping block 22 is driven to move relative to each other, and the anti-slip strips on the outside of the clamping block 22 are used to clamp the outer walls of the sampling bottle 13 on both sides to prevent loosening, and the clamping block 22 can be driven to expand and contract in the groove of the groove block 20 through the compression and expansion of the spring 21, so as to protect the outer wall of the sampling bottle 13, and the first motor 3 is started to drive the screw rod 4 to rotate, and the screw rod 4 drives the nut pair 11 to move, thereby driving the lifting assembly and the support plate 10 to move along the guide column 5, driving the support plate 10 and the sampling bottle 13 to move, and when reaching the sampling slot above the sampling plate 2, the cylinder 8 contracts to drive the lifting column 9 and the support plate 10 to descend, thereby driving the sampling bottle 13 to descend, and the specimen liquid in the sampling bottle 13 is controlled to flow out through the solenoid valve 15 and drips into the sampling slot on the sampling plate 2 below.

[0034] It should be noted that, in this article, relational terms such as first and second, etc. are only used to distinguish one entity or operation from another entity or operation, and do not necessarily require or imply any such actual relationship or order between these entities or operations. Moreover, the terms "include", "comprise" or any other variants thereof are intended to cover non-exclusive inclusion, so that a process, method, article or device including a series of elements includes not only those elements, but also other elements not explicitly listed, or also includes elements inherent to such process, method, article or device.

[0035] Although embodiments of the present invention have been shown and described, it will be appreciated by those skilled in the art that various changes, modifications, substitutions and variations may be made to the embodiments without departing from the principles and spirit of the present invention, and that the scope of the present invention is defined by the appended claims and their equivalents.

Claims

1. A nucleic acid detection reagent sample addition and extraction device, comprising a placement table (1), characterized in that: A sampling plate (2) is arranged on the top of the placement platform (1), a first motor (3) is fixedly connected to the left side of the placement platform (1), a lead screw (4) is fixedly connected to the output end of the first motor (3), a guide column (5) is fixedly connected to the right side of the placement platform (1), a nut pair (11) is threadedly connected to the outside of the lead screw (4), a lifting component is arranged on the top of the nut pair (11), a lifting component is also arranged on the outside of the guide column (5), and the tops of the two lifting components are connected to a support plate (10), and a support plate (10) is penetrated and provided with a There are three through holes (12), a sampling bottle (13) is arranged in the through hole (12), a liquid outlet pipe (14) is fixedly connected to the bottom of the sampling bottle (13), a second motor (16) is fixedly connected to the left side of the support plate (10), a bidirectional threaded rod (17) is fixedly connected to the output end of the second motor (16), both sides of the bidirectional threaded rod (17) are threadedly connected to the outside of the moving plates (18), the two moving plates (18) are fixedly connected to the opposite side with a groove block (20), and a clamping block (22) is slidably connected inside the groove block (20).

2. A nucleic acid detection reagent sampling and extraction device according to claim 1, characterized in that: The lifting assembly comprises a moving block (6), the bottom of the left moving block (6) is fixedly connected to a nut pair (11), the right moving block (6) penetrates and is slidably connected to the outside of a guide column (5), the tops of the two moving blocks (6) are each provided with a placement groove (7), a cylinder (8) is fixedly connected in the placement groove (7), the output end of the cylinder (8) is fixedly connected to a lifting column (9), and the top of the lifting column (9) is fixedly connected to a support plate (10).

3. A nucleic acid detection reagent sample addition and extraction device according to claim 1, characterized in that: A solenoid valve (15) is arranged outside the liquid outlet pipe (14).

4. A nucleic acid detection reagent sampling and extraction device according to claim 1, characterized in that: A guide rod (19) passes through and is slidably connected to the left end of the movable plate (18), and both ends of the guide rod (19) are fixedly connected to the support plate (10).

5. A nucleic acid detection reagent sampling and extraction device according to claim 1, characterized in that: Three springs (21) are fixedly connected inside the groove block (20), and the other end of the spring (21) is fixedly connected to the clamping block (22).

6. A nucleic acid detection reagent sampling and extraction device according to claim 1, characterized in that: The clamping block (22) is arranged outside the sampling bottle (13).

7. A nucleic acid detection reagent sampling and extraction device according to claim 2, characterized in that: The bottom of the lifting column (9) is arranged in the placement groove (7), and the outside of the lifting column (9) is slidably connected to the inner wall of the placement groove (7).

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