Incubator for cell culture

By integrated temperature and humidity sensors, temperature control modules and humidity control modules in the cultivation box in cell culture, the problem of poor temperature and humidity control in the existing technology has been solved, and the stable control of the cell culture environment is realized, and the success of cell culture has been improved. Rate and reliability.

CN222411617UActive Publication Date: 2025-01-28HUAXIAYUAN (JIANGSU) CELL GENE ENGINEERING GROUP CO LTD
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Patent Information

Application Number
CN202420716671.7
Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
Filing Date
2024-04-09
Publication Date
2025-01-28
Estimated Expiration
2034-04-09

AI Technical Summary

Technical Problem

The existing cell culture incubator lacks a control mechanism for the internal temperature and humidity of the box, and cannot effectively monitor and regulate the temperature and humidity, resulting in unstable cell culture environment and affecting the success rate and reliability of cell culture.

Method used

It is designed to cultivate a culture training box that includes the temperature and humidity sensor, the temperature control module and the humidity control module. Through the combination of these modules, the real -time monitoring and accurate adjustment of the temperature and humidity inside the box can be achieved.

Benefits of technology

The stable control of the cell culture environment is realized, the temperature and humidity are within the appropriate range, and the success rate and reliability of cell culture are improved.

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Abstract

The utility model discloses an incubator for cell culture, which comprises an incubator body, through the cooperative use of a temperature and humidity sensor, a temperature control module and a humidity control module, the temperature and humidity sensor can monitor the temperature and humidity conditions in the incubator body in real time, and the temperature and humidity sensor can accurately sense the temperature and humidity changes in the incubator body; the data is transmitted to the control system, so that researchers can know the temperature and humidity conditions of the cell culture environment in real time, and the growth and reproduction of cells in a proper environment are ensured; due to the existence of the temperature control module and the humidity control module, the box body has accurate temperature and humidity adjusting capacity, and through the two modules, the box body can perform heating, refrigeration, humidification or dehumidification operation according to temperature and humidity data monitored by the temperature and humidity sensor so as to maintain the temperature and the humidity in the box body within a set range, and the temperature and the humidity in the box body can be controlled. The accurate regulation capability ensures the stability of a cell culture environment, and the success rate and reliability of cell culture are improved.
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Description

Technical Field

[0001] The utility model relates to the technical field of cell culture, in particular to a culture box for cell culture. Background Art

[0002] With the rapid development of biomedicine, cells need to be cultured. Cell culture incubators are commonly used tools in cell culture. In existing cell culture incubators, culture dishes are laid flat on a plate body, and the plate body is generally movable. However, in this placement method, when taking out several culture dishes located deep inside, since the culture dishes are laid flat on the plate body, the culture dishes block each other. When taking them out, they are subject to height restrictions, which makes operation inconvenient. It is very easy to cause the culture dishes near the target culture dishes to shake, causing the liquid in the culture dishes to overflow, the incubator to be contaminated, and lead to culture failure.

[0003] For example, a cell culture incubator (Announcement No.: CN212270126U) includes a box body, a fixed block is welded on the inner wall of the box body, a groove is provided in the fixed block, a support plate is slidably arranged in the groove, and the cell culture incubator is provided with rollers and balls in the support plate. When the support plate is pulled, the friction between the support plate and the fixed block can be reduced, which is convenient for removal or insertion. After the support plate is inserted, the roller squeezes and fixes the support plate, which is convenient for the user to pull out or fix the support plate, which is convenient for use and ensures stability. Loosen the threaded sleeve and push the semicircular clamping block. The connecting rod will squeeze the second spring, and then tighten the threaded sleeve to place the culture dish between the two semicircular clamping blocks. Loosen the threaded sleeve and clamp the culture dish under the action of the restoring force of the second spring to prevent the culture dish from shaking and causing the internal culture fluid to overflow, thereby improving safety.

[0004] But the device still has the following defects:

[0005] When the device is in use, there is a lack of a mechanism to control the temperature and humidity inside the box. The temperature and humidity inside the box cannot be well detected and adjusted, and the temperature and humidity inside the box cannot be well guaranteed to be at a level suitable for cell culture. It is impossible to create a suitable temperature and humidity environment, which is not conducive to cell culture work. Therefore, we need to propose an incubator for cell culture. Utility Model Content

[0006] The utility model aims to provide an incubator for cell culture, aiming to solve the problem that the prior art lacks a mechanism for controlling the temperature and humidity inside the box, the temperature and humidity inside the box cannot be well detected and adjusted, the temperature and humidity inside the box cannot be well guaranteed to be at a level suitable for cell culture, and a suitable temperature and humidity environment cannot be created, which is not conducive to cell culture work.

[0007] In order to achieve the above purpose, the utility model provides the following technical solutions:

[0008] A cell culture incubator, comprising a box, a temperature and humidity sensor is fixedly installed on the top of the box, a temperature control module is fixedly embedded in the bottom of the box, a humidity control module is fixedly embedded on one side of the box located at the temperature control module, a control panel is fixedly installed on one side wall of the box, and the temperature and humidity sensor, the temperature control module and the humidity control module are all electrically connected to the control panel through wires;

[0009] Three groups of culture trays are arranged inside the box, and four groups of culture dish placement slots are opened on the top of the three groups of culture trays. Blind holes are opened on the inner walls of both sides of the culture dish placement slots respectively, and clamping components for positioning the culture dishes are arranged inside the blind holes.

[0010] Preferably, the clamping assembly comprises a telescopic spring, one end of which is fixedly connected to an inner wall of one side of the blind hole, the other end of which is fixedly connected to a connecting rod, and one end of which is fixedly connected to a clamping plate.

[0011] Preferably, the connecting rod is adapted to the blind hole, and the connecting rod is slidably inserted into the interior of the blind hole.

[0012] Preferably, six groups of mounting bars are fixedly connected to the inner walls on both sides of the box body, the six groups of mounting bars are symmetrically arranged in pairs, and a slide groove is opened on one side wall of the six groups of mounting bars. Slide blocks are fixedly connected to the side walls on both sides of the three groups of culture trays, and the slide blocks are slidably connected to the inside of the slide groove.

[0013] Preferably, the tops of the six groups of mounting strips are all provided with locking assemblies for positioning the sliders, the locking assemblies comprising sleeves, the sleeves being fixedly embedded in the tops of the mounting strips, a positioning rod being slidably inserted into the interior of the sleeves, the bottom end of the positioning rod being inserted into the interior of the sliders, and the top end of the positioning rod being fixedly connected to a connecting block.

[0014] Preferably, it also includes a return spring, the top end of which is fixedly connected to the bottom of the connecting block, the bottom end of which is fixedly connected to the top end of the sleeve, and the return spring is movably sleeved on the outer wall of the positioning rod.

[0015] Preferably, the tops of the three groups of culture trays are each provided with a plurality of through grooves, and a push-pull handle is fixedly connected to one side wall of the three groups of culture trays.

[0016] Preferably, a box door is hinged on one side wall of the box body through a hinge, and an observation window is provided on the box door.

[0017] Compared with the prior art, the beneficial effects of the utility model are:

[0018] The utility model sets a temperature and humidity sensor, a temperature control module and a humidity control module for coordinated use. The temperature and humidity sensor can monitor the temperature and humidity conditions inside the box in real time. The temperature and humidity sensor can accurately sense the temperature and humidity changes in the box and transmit the data to the control system. In this way, researchers can understand the temperature and humidity conditions of the cell culture environment in real time to ensure that the cells grow and reproduce in a suitable environment. The existence of the temperature control module and the humidity control module enables the box to have accurate temperature and humidity adjustment capabilities. Through these two modules, the box can perform heating, cooling, humidification or dehumidification operations according to the temperature and humidity data monitored by the temperature and humidity sensor to maintain the temperature and humidity in the box within the set range. This precise adjustment capability ensures the stability of the cell culture environment and improves the success rate and reliability of cell culture. BRIEF DESCRIPTION OF THE DRAWINGS

[0019] Figure 1 It is a schematic diagram of the structure of the utility model;

[0020] Figure 2 It is a schematic diagram of the structure inside the box of the utility model;

[0021] Figure 3 It is a structural schematic diagram of the culture support plate and the locking assembly of the utility model;

[0022] Figure 4 For this utility model Figure 3 The enlarged structural diagram at A in the middle;

[0023] Figure 5 It is a structural schematic diagram of the culture support plate and the clamping assembly of the utility model.

[0024] In the figure: 1. box body; 2. temperature and humidity sensor; 3. temperature control module; 4. humidity control module; 5. control panel; 6. culture tray; 7. culture dish placement slot; 8. blind hole; 9. clamping assembly; 901. telescopic spring; 902. connecting rod; 903. clamping plate; 10. mounting strip; 11. slide groove; 12. slider; 13. locking assembly; 1301. sleeve; 1302. positioning rod; 1303. connecting block; 14. reset spring; 15. through groove; 16. push-pull handle; 17. box door. DETAILED DESCRIPTION

[0025] The following will be combined with the drawings in the embodiments of the utility model to clearly and completely describe the technical solutions in the embodiments of the utility model. Obviously, the described embodiments are only part of the embodiments of the utility model, not all of the embodiments. Based on the embodiments in the utility model, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the utility model.

[0026] See also Figure 1-5 , the utility model provides a technical solution:

[0027] A cell culture incubator comprises a box body 1, a temperature and humidity sensor 2 is fixedly installed on the top of the box body 1, a temperature control module 3 is fixedly embedded on the bottom of the box body 1, a humidity control module 4 is fixedly embedded on one side of the box body 1 located at the temperature control module 3, and a control panel 5 is fixedly installed on one side wall of the box body 1. The temperature and humidity sensor 2, the temperature control module 3 and the humidity control module 4 are all electrically connected to the control panel 5 through wires. The temperature and humidity sensor 2 detects the temperature and humidity changes inside the box body 1 in real time and transmits the data to the control panel 5. After receiving the data, the control panel 5 presents them to researchers in an intuitive manner (such as a digital display or a graphical interface), so that they can understand the box in real time. 1, then the control panel 5 compares the received temperature and humidity data with the preset target values. If the actual temperature and humidity values ​​deviate from the target range, the control panel 5 sends corresponding adjustment instructions to the temperature control module 3 and the humidity control module 4. After receiving the instructions, the temperature control module 3 adjusts the temperature in the box 1 through the heating or cooling element according to the difference between the actual temperature and the target temperature. If the temperature is too low, the heating element will start to increase the temperature; if the temperature is too high, the cooling element will work to lower the temperature. At the same time, the temperature control module 3 will also continuously adjust the intensity of heating or cooling according to the feedback data of the sensor to ensure that the temperature is stable within the target range;

[0028] Three groups of culture trays 6 are arranged inside the box 1, and four groups of culture dish placement slots 7 are opened on the top of the three groups of culture trays 6. Blind holes 8 are respectively opened on the inner walls of the two sides of the culture dish placement slots 7. The blind holes 8 are provided inside the clamping components 9 for positioning the culture dishes. The utility model can heat, cool, humidify or dehumidify the box 1 according to the temperature and humidity data monitored by the temperature and humidity sensor 2 to maintain the temperature and humidity in the box 1 within the set range. This precise adjustment ability ensures the stability of the cell culture environment and improves the success rate and reliability of cell culture.

[0029] The clamping assembly 9 includes a telescopic spring 901, one end of which is fixedly connected to an inner wall of one side of the blind hole 8, the other end of which is fixedly connected to a connecting rod 902, and one end of which is fixedly connected to a clamping plate 903;

[0030] The connecting rod 902 is adapted to the blind hole 8, and the connecting rod 902 is slidably inserted into the inside of the blind hole 8. When the researcher places the cell culture dish (not shown in the figure) inside the culture dish placement groove 7, the rebound force of the telescopic spring 901 can be used to drive the clamping plate 903 to clamp and position the cell culture dish to avoid deviation or even shaking and tilting.

[0031] Six groups of mounting bars 10 are fixedly connected to the inner walls on both sides of the box body 1, and the six groups of mounting bars 10 are symmetrically arranged in pairs. A slide groove 11 is opened on one side wall of each of the six groups of mounting bars 10. Slide blocks 12 are fixedly connected to the side walls on both sides of the three groups of culture trays 6, and the slide blocks 12 are slidably connected to the inside of the slide groove 11.

[0032] The top of each of the six groups of mounting bars 10 is provided with a locking assembly 13 for positioning the slider 12. The locking assembly 13 includes a sleeve 1301, which is fixedly embedded in the top of the mounting bar 10. A positioning rod 1302 is slidably inserted inside the sleeve 1301. The bottom end of the positioning rod 1302 is inserted into the inside of the slider 12. The top end of the positioning rod 1302 is fixedly connected with a connecting block 1303.

[0033] The reset spring 14 is also included. The top of the reset spring 14 is fixedly connected to the bottom of the connecting block 1303. The bottom end of the reset spring 14 is fixedly connected to the top of the sleeve 1301. The reset spring 14 is movably sleeved on the outer wall of the positioning rod 1302. The bottom end of the positioning rod 1302 is set to be hemispherical. The top of the slider 12 is provided with a positioning hole that matches the bottom end of the positioning rod 1302. When the staff takes out or installs the culture tray 6, the reset spring 14 can be adaptively telescopically adjusted, thereby driving the positioning rod 1302 to be inserted into the inside of the positioning hole, so as to achieve the function of locking and positioning the culture tray 6, so as to improve the stability of the incubator.

[0034] The tops of the three groups of culture trays 6 are all provided with a plurality of through grooves 15, and the side walls of the three groups of culture trays 6 are all fixedly connected with push-pull handles 16. By providing the push-pull handles 16, researchers can conveniently disassemble and assemble the culture trays 6;

[0035] A door 17 is hinged on one side wall of the box body 1 through a hinge, and an observation window is provided on the door 17. Researchers can view the cell culture status inside the box body 1 in real time through the observation window.

[0036] Although embodiments of the present invention have been shown and described, it will be appreciated by those skilled in the art that various changes, modifications, substitutions and variations may be made to the embodiments without departing from the principles and spirit of the present invention, and that the scope of the present invention is defined by the appended claims and their equivalents.

Claims

1. A cell culture incubator, comprising a box body (1), characterized in that: A temperature and humidity sensor (2) is fixedly mounted on the inner top of the box (1), a temperature control module (3) is fixedly embedded on the bottom of the box (1), a humidity control module (4) is fixedly embedded on one side of the box (1) located on the temperature control module (3), a control panel (5) is fixedly mounted on one side wall of the box (1), and the temperature and humidity sensor (2), the temperature control module (3) and the humidity control module (4) are all electrically connected to the control panel (5) via wires; Three groups of culture trays (6) are arranged inside the box (1), four groups of culture dish placement grooves (7) are opened on the top of the three groups of culture trays (6), blind holes (8) are opened on the inner walls of both sides of the culture dish placement grooves (7), and clamping components (9) for positioning the culture dishes are arranged inside the blind holes (8).

2. A cell culture incubator according to claim 1, characterized in that: The clamping assembly (9) comprises a telescopic spring (901), one end of the telescopic spring (901) is fixedly connected to an inner wall of one side of the blind hole (8), the other end of the telescopic spring (901) is fixedly connected to a connecting rod (902), and one end of the connecting rod (902) is fixedly connected to a clamping plate (903).

3. A cell culture incubator according to claim 2, characterized in that: The connecting rod (902) is adapted to the blind hole (8), and the connecting rod (902) is slidably inserted into the interior of the blind hole (8).

4. The cell culture incubator according to claim 1, characterized in that: Six groups of mounting bars (10) are fixedly connected to the inner walls on both sides of the box body (1), and the six groups of mounting bars (10) are symmetrically arranged in pairs. A slide groove (11) is opened on one side wall of the six groups of mounting bars (10). Slide blocks (12) are fixedly connected to the side walls on both sides of the three groups of culture trays (6), and the slide blocks (12) are slidably connected to the inside of the slide groove (11).

5. A cell culture incubator according to claim 4, characterized in that: The top of each of the six groups of mounting strips (10) is provided with a locking assembly (13) for positioning the slider (12), wherein the locking assembly (13) comprises a sleeve (1301), wherein the sleeve (1301) is fixedly embedded in the top of the mounting strip (10), wherein a positioning rod (1302) is slidably inserted inside the sleeve (1301), wherein the bottom end of the positioning rod (1302) is inserted into the inside of the slider (12), and the top end of the positioning rod (1302) is fixedly connected to a connecting block (1303).

6. A cell culture incubator according to claim 5, characterized in that: It also includes a return spring (14), the top end of the return spring (14) is fixedly connected to the bottom of the connecting block (1303), the bottom end of the return spring (14) is fixedly connected to the top end of the sleeve (1301), and the return spring (14) is movably sleeved on the outer wall of the positioning rod (1302).

7. The cell culture incubator according to claim 1, characterized in that: The tops of the three groups of culture trays (6) are all provided with a plurality of through grooves (15), and a push-pull handle (16) is fixedly connected to one side wall of the three groups of culture trays (6).

8. The cell culture incubator according to claim 1, characterized in that: A box door (17) is hingedly connected to a side wall of the box body (1) via a hinge, and an observation window is arranged on the box door (17).

Citation Information

Patent Citations

  • Incubator for cell culture

    CN212270126U