Glass slide and cover glass bonding structure

By using the combination of light -sensitive glue and ultraviolet lamps, the rapid, efficient, and non -toxic adhesion of the glass and the glass sheet is realized, and the problem of the volatilization and static drying time in existing technologies has been solved. The efficiency and accuracy of scanning.

CN222419712UActive Publication Date: 2025-01-28SUZHOU RUIQIAN TECH CO LTD
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Patent Information

Application Number
CN202420708252.9
Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
Filing Date
2024-04-08
Publication Date
2025-01-28
Estimated Expiration
2034-04-08

AI Technical Summary

Technical Problem

In the prior art, during cell scanning, the volatility of xylene in resin glue poses a threat to the environment and personnel safety, and the long-drying time of static reduction of scanning efficiency, and may lead to coverslip offset, affecting the scanning results. accuracy.

Method used

The combination of light -sensitive glue and ultraviolet lamps is used to direct the rapid adhesion of the glass with the light -sensitive glue through the ultraviolet light to avoid the static drying process of resin glue and ensure the non -toxicity of the bonding.

Benefits of technology

The rapid, efficient, and non -toxic adhesion between the glass and the cover glass are achieved, avoiding relative movement, and improving the scanning efficiency and accuracy.

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Abstract

The utility model belongs to the technical field of cell sealing sheets, and discloses a slide and cover glass bonding structure which comprises a slide, a cover glass and photosensitive glue, the photosensitive glue is arranged on the upper surface of the slide, the cover glass covers the photosensitive glue, and the slide, the photosensitive glue and the cover glass can be bonded into a whole by directly irradiating the photosensitive glue through an ultraviolet lamp. According to the utility model, the photosensitive glue can be quickly dried by using the ultraviolet lamp, and the glass slide and the cover glass are tightly attached by using the photosensitive glue, so that a glass slide and cover glass bonding structure is formed and is used for placing and scanning target cells. Specifically, the photosensitive adhesive is non-toxic and harmless, does not cause harm to the environment and personnel in the bonding process and after a bonding structure of the glass slide and the cover glass is formed, can realize rapid and efficient bonding between the glass slide and the cover glass under the cooperation with the ultraviolet lamp, improves the scanning efficiency, and also ensures the scanning precision.
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Description

Technical Field

[0001] The utility model relates to the technical field of cell sealing, in particular to a glass slide and cover glass bonding structure. Background Art

[0002] In the prior art, in order to scan cells, a substance containing target cells is often placed on a glass slide, and a cover glass is covered on the cells, and the cover glass is bonded to the glass slide by resin glue, so that the target cells can be transferred and detected. However, when adding resin glue, it is usually necessary to add xylene to the resin glue for dilution, and then the diluted resin glue is transferred to the glass slide or cover glass using a dropper or other liquid transfer equipment, and the two are aligned to make them fit closely and squeeze out bubbles, and dry for about 96 hours until completely dry. The xylene added to the resin glue during its addition and drying process will evaporate into the air, and xylene is harmful to the environment and personnel safety, and there is a certain safety risk. At the same time, the time of static drying is too long, which greatly reduces the scanning efficiency of the target cells. If the drying is incomplete, the cover glass may also be offset during the scanning process, which seriously affects the scanning results and makes the final diagnosis inaccurate. Therefore, how to ensure fast, efficient and non-toxic bonding between the glass slide and the cover glass, ensure that the two will not move relative to each other during the scanning process, and effectively improve the overall scanning efficiency and accuracy are the problems that the current technicians in this field need to solve. Utility Model Content

[0003] The utility model aims to provide a glass slide and cover glass bonding structure to ensure fast, efficient and non-toxic bonding between the glass slide and the cover glass, to ensure that the two will not move relative to each other during the scanning process, and to effectively improve the overall scanning efficiency and accuracy.

[0004] To achieve this purpose, the utility model adopts the following technical solutions:

[0005] A glass slide and cover glass bonding structure, comprising:

[0006] A glass slide, a cover glass and a photosensitive adhesive, wherein the photosensitive adhesive is arranged on the upper surface of the glass slide, the cover glass is covered on the photosensitive adhesive, and the glass slide, the photosensitive adhesive and the cover glass can be bonded into one by directly irradiating the photosensitive adhesive with an ultraviolet lamp.

[0007] Optionally, a placement area is provided on the glass slide, and one side of the photosensitive adhesive is attached to the placement area.

[0008] Optionally, a hand-holding area is provided on the glass slide to facilitate moving the glass slide.

[0009] As an option, the size of the cover glass is smaller than or equal to the size of the placement area.

[0010] As an option, the photosensitive adhesive is configured as a circular structure, and the diameter of the photosensitive adhesive is smaller than the width of the placement area.

[0011] As an option, the size of the hand-holding area is smaller than the size of the placement area.

[0012] As an option, the glass slide and the cover glass are both made of transparent materials.

[0013] Optionally, there are no bubbles between the glass slide and the photosensitive adhesive, between the cover glass and the photosensitive adhesive, and between the glass slide and the cover glass.

[0014] Optionally, the photosensitive adhesive is made of non-toxic material.

[0015] As an option, the irradiation area of ​​the ultraviolet lamp can cover the bonding area between the cover glass and the photosensitive adhesive.

[0016] Beneficial effects of the utility model:

[0017] The utility model can quickly dry the photosensitive adhesive by using an ultraviolet lamp, and use the photosensitive adhesive sandwiched between the glass slide and the cover glass to achieve a close fit between the glass slide and the cover glass, and form an integral structure of the glass slide and cover glass bonding structure for the placement and scanning of target cells. Specifically, the photosensitive adhesive is non-toxic and harmless, and will not cause harm to the environment and personnel during the bonding process and after the glass slide and cover glass bonding structure is formed. At the same time, the cooperation of the ultraviolet lamp and the photosensitive adhesive can effectively avoid the process of the resin glue in the prior art being statically dried for a long time, thereby achieving fast and efficient bonding between the glass slide and the cover glass, ensuring that the two will not move relative to each other during the subsequent scanning process, which not only improves the scanning efficiency, but also ensures the scanning accuracy. BRIEF DESCRIPTION OF THE DRAWINGS

[0018] Figure 1 It is a schematic diagram of the glass slide and cover glass bonding structure according to the embodiment of the utility model in an unbonded state;

[0019] Figure 2 It is a structural schematic diagram of the glass slide and cover glass bonding structure described in an embodiment of the utility model in a bonding state.

[0020] In the figure:

[0021] 10-glass slide; 11-placing area; 12-handling area; 20-cover glass; 30-photosensitive adhesive; 40-ultraviolet lamp. DETAILED DESCRIPTION

[0022] The embodiments of the present invention are described in detail below, and examples of the embodiments are shown in the accompanying drawings, wherein the same or similar reference numerals throughout represent the same or similar components or components having the same or similar functions. The embodiments described below with reference to the accompanying drawings are exemplary and are intended to be used to explain the present invention, and should not be construed as limiting the present invention.

[0023] In the description of the present invention, unless otherwise clearly specified and limited, the terms "connected", "connected", and "fixed" should be understood in a broad sense, for example, it can be a fixed connection or a detachable connection, it can be a mechanical connection or an electrical connection, it can be a direct connection or an indirect connection through an intermediate medium, it can be the internal connection of two elements or the interaction relationship between two elements. For ordinary technicians in this field, the specific meanings of the above terms in the present invention can be understood according to specific circumstances.

[0024] In the description of the present utility model, unless otherwise clearly stipulated and limited, a first feature being "above" or "below" a second feature may include the first feature and the second feature being in direct contact, or may include the first feature and the second feature being in contact not directly but through another feature between them. Moreover, a first feature being "above", "above" and "above" a second feature includes the first feature being directly above and obliquely above the second feature, or simply indicates that the first feature is higher in level than the second feature. A first feature being "below", "below" and "below" a second feature includes the first feature being directly below and obliquely below the second feature, or simply indicates that the first feature is lower in level than the second feature.

[0025] In the prior art, in order to scan cells, a substance containing target cells is often placed on a glass slide, and a cover glass is covered on the cells, and the cover glass is bonded to the glass slide by resin glue, so that the target cells can be transferred and detected. However, when adding resin glue, it is usually necessary to add xylene to the resin glue for dilution, and then the diluted resin glue is transferred to the glass slide or cover glass using a dropper or other liquid transfer equipment, and the two are aligned to make them fit closely, squeeze out bubbles, and dry for about 96 hours until completely dry. The xylene added to the resin glue during its addition and drying process will evaporate into the air, and xylene is harmful to the environment and personnel safety, and there is a certain safety risk. At the same time, the time of static drying is too long, which greatly reduces the scanning efficiency of the target cells. If the drying is incomplete, the cover glass may also be offset during the scanning process, which seriously affects the scanning results and makes the final diagnosis inaccurate. Therefore, how to ensure fast, efficient and non-toxic bonding between the glass slide and the cover glass, ensure that the two will not move relative to each other during the scanning process, and effectively improve the overall scanning efficiency and accuracy are the problems that the current technicians in this field need to solve.

[0026] The technical solution of this embodiment is further explained below with reference to the accompanying drawings and through specific implementation methods.

[0027] like Figure 1-Figure 2 As shown, this embodiment provides a glass slide and cover glass bonding structure, including a glass slide 10, a cover glass 20 and a photosensitive adhesive 30, the photosensitive adhesive 30 is arranged on the upper surface of the glass slide 10, the cover glass 20 is covered on the photosensitive adhesive 30, and the glass slide 10, the photosensitive adhesive 30 and the cover glass 20 can be bonded into one by directly irradiating the photosensitive adhesive 30 with an ultraviolet lamp 40.

[0028] Specifically, in this embodiment, the use of the ultraviolet lamp 40 can quickly dry the photosensitive adhesive 30, and the photosensitive adhesive 30 sandwiched between the glass slide 10 and the cover glass 20 can be used to achieve a close fit between the glass slide 10 and the cover glass 20, and form a whole glass slide and cover glass bonding structure for the placement and scanning of target cells. Specifically, the photosensitive adhesive 30 is non-toxic and harmless, and will not cause harm to the environment and personnel during the bonding process and after the glass slide and cover glass bonding structure is formed. At the same time, the cooperation of the ultraviolet lamp 40 and the photosensitive adhesive 30 can effectively avoid the process of the resin glue in the prior art being statically dried for a long time, thereby achieving fast and efficient bonding between the glass slide 10 and the cover glass 20, ensuring that the two will not move relative to each other during the subsequent scanning process, which not only improves the scanning efficiency, but also ensures the scanning accuracy.

[0029] The specific structure of the bonding structure between the glass slide and the cover glass in this embodiment is described below.

[0030] like Figure 1-Figure 2 As shown, in this embodiment, the glass slide and cover glass bonding structure includes a glass slide 10, a cover glass 20 and a photosensitive adhesive 30. Specifically, the photosensitive adhesive 30 is arranged on the upper surface of the glass slide 10, and the cover glass 20 is covered on the photosensitive adhesive 30, that is, the photosensitive adhesive 30 is sandwiched between the glass slide 10 and the cover glass 20. Further, the glass slide 10, the photosensitive adhesive 30 and the cover glass 20 can be bonded together by directing the ultraviolet lamp 40 to the photosensitive adhesive 30 to form a glass slide and cover glass bonding structure, so that the glass slide 10 and the cover glass 20 are bonded together, and then when the cells on the glass slide 10 are scanned later, the position of the cover glass 20 will not be offset, thereby ensuring the accuracy of the scanning result.

[0031] Specifically, in this embodiment, a placement area 11 and a hand-holding area 12 are provided on the glass slide 10. Figure 1 and Figure 2As shown, one side of the photosensitive adhesive 30 is attached to the placement area 11, and the other side is attached to the cover glass 20. Exemplarily, the glass slide 10 is set as a rectangular structure, and the placement area 11 and the hand-held area 12 are adjacently arranged. In this embodiment, the size of the hand-held area 12 is smaller than the size of the placement area 11, and the hand-held area 12 is used by the operator to move and transfer the glass slide 10. Specifically, the partitioning of the placement area 11 and the hand-held area 12 makes it difficult to misplace the position of the subsequent photosensitive adhesive 30, and after the photosensitive adhesive 30 is placed in the placement area 11 or after the cover glass 20 is covered on the photosensitive adhesive 30, the operator can transfer the entire glass slide 10 by holding the hand-held area 12, and can also adjust the position of the glass slide and the cover glass bonding structure under the ultraviolet lamp 40.

[0032] Optionally, in this embodiment, the cover glass 20 is also configured as a rectangular structure, and the size of the cover glass 20 is less than or equal to the size of the placement area 11, so that the cover glass 20 can be stably placed on the placement area 11. Further, the photosensitive adhesive 30 is configured as a circular structure, and the diameter of the photosensitive adhesive 30 is less than the width of the placement area 11. At the same time, the diameter of the photosensitive adhesive 30 is also less than the width of the cover glass 20, thereby ensuring that the photosensitive adhesive 30 is stably placed on the placement area 11 without overflowing, and ensuring that the cover glass 20 can be completely covered on the photosensitive adhesive 30, thereby achieving stable adhesion between the cover glass 20, the photosensitive adhesive 30 and the glass slide 10.

[0033] Specifically, there are no bubbles between the glass slide 10 and the photosensitive adhesive 30, between the cover glass 20 and the photosensitive adhesive 30, and between the glass slide 10 and the cover glass 20 in the glass slide and cover glass bonding structure, so that the bonding effect between the glass slide 10, the photosensitive adhesive 30 and the cover glass 20 can be ensured, and relative movement will not occur after bonding, so that the overall stability of the glass slide and cover glass bonding structure is better. Specifically, the thickness of the glass slide 10, the cover glass 20 and the photosensitive adhesive 30 can be set as needed to ensure the stability of the connection between the three, and the absence of gap bubbles in the final glass slide and cover glass bonding structure.

[0034] Optionally, the glass slide 10 and the cover glass 20 are both made of transparent materials, so that the position of the photosensitive adhesive 30 can be observed and subsequent scanning observation is convenient. Further, the photosensitive adhesive 30 is made of non-toxic materials, so as to ensure that during the entire bonding process, the formed glass slide and cover glass bonding mechanism will not cause pollution to the environment or endanger the safety of the operator.

[0035] like Figure 2As shown, the irradiation area of ​​the ultraviolet lamp 40 in this embodiment can cover the bonding area of ​​the cover glass 20 and the photosensitive adhesive 30, thereby ensuring that the ultraviolet lamp 40 can fully irradiate the photosensitive adhesive 30, and enable the glass slide 10, the photosensitive adhesive 30 and the cover glass 20 to form a glass slide and cover glass bonding structure in a relatively short time, thereby achieving a fast, efficient and non-toxic bonding operation, thereby improving the overall scanning preparation efficiency while ensuring the quality of subsequent scanning.

[0036] For example, after the operator covers the cover glass 20 on the photosensitive adhesive 30 and makes the center lines of the two on the same straight line, the operator can transfer the glass slide 10, the photosensitive adhesive 30 and the cover glass 20 that have not been firmly attached to the bottom of the ultraviolet lamp 40 through the hand-held area 12 on the glass slide 10, and adjust the ultraviolet lamp 40 to directly irradiate the photosensitive adhesive 30, so that it can quickly dry and solidify to achieve the bonding effect. Further, in this embodiment, the ultraviolet lamp 40 is arranged perpendicular to the cover glass 20, so that the light of the ultraviolet lamp 40 can be irradiated on the cover glass 20 as much as possible, thereby improving the direct effect and its drying, solidification and bonding efficiency.

[0037] Obviously, the above embodiments of the present invention are merely examples for clearly illustrating the present invention, and are not intended to limit the implementation methods of the present invention. For those skilled in the art, other different forms of changes or modifications can be made based on the above description. It is not necessary and impossible to list all implementation methods here. Any modifications, equivalent substitutions, and improvements made within the spirit and principles of the present invention shall be included in the protection scope of the claims of the present invention.

Claims

1. A glass slide and cover glass bonding structure, characterized in that: include: A glass slide (10), a cover glass (20) and a photosensitive adhesive (30), wherein the photosensitive adhesive (30) is arranged on the upper surface of the glass slide (10), the cover glass (20) is covered on the photosensitive adhesive (30), and the glass slide (10), the photosensitive adhesive (30) and the cover glass (20) can be bonded together by directly irradiating the photosensitive adhesive (30) with an ultraviolet lamp (40).

2. The glass slide and cover glass bonding structure according to claim 1, characterized in that: A placement area (11) is provided on the glass slide (10), and one side of the photosensitive adhesive (30) is attached to the placement area (11).

3. The glass slide and cover glass bonding structure according to claim 2, characterized in that: The glass slide (10) is also provided with a hand-holding area (12) to facilitate the movement of the glass slide (10).

4. The glass slide and cover glass bonding structure according to claim 2, characterized in that: The size of the cover glass (20) is smaller than or equal to the size of the placement area (11).

5. The glass slide and cover glass bonding structure according to claim 2, characterized in that: The photosensitive adhesive (30) is arranged in a circular structure, and the diameter of the photosensitive adhesive (30) is smaller than the width of the placement area (11).

6. The glass slide and cover glass bonding structure according to claim 3, characterized in that: The size of the hand-holding area (12) is smaller than the size of the placement area (11).

7. The glass slide and cover glass bonding structure according to claim 1, characterized in that: The glass slide (10) and the cover glass (20) are both made of transparent materials.

8. The glass slide and cover glass bonding structure according to claim 1, characterized in that: There are no bubbles between the glass slide (10) and the photosensitive adhesive (30), between the cover glass (20) and the photosensitive adhesive (30), and between the glass slide (10) and the cover glass (20).

9. The glass slide and cover glass bonding structure according to claim 1, characterized in that: The photosensitive adhesive (30) is made of non-toxic material.

10. The glass slide and cover glass bonding structure according to claim 1, characterized in that: The irradiation area of ​​the ultraviolet lamp (40) can cover the bonding area between the cover glass (20) and the photosensitive adhesive (30).

Citation Information

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