Ultrasonic treatment and imaging integrated probe and cavity FUS treatment system
By integrating the therapeutic transducer and imaging transducer in the integrated ultrasound therapy and imaging probe, the problem of combining ultrasound imaging and ultrasound therapy modules in the prior art is solved, and diagnosis, treatment and monitoring are realized in a small space Integration improves the accuracy and reliability of treatment.
Patent Information
- Application Number
- CN202323625160.9
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- Filing Date
- 2023-12-28
- Publication Date
- 2025-02-07
- Estimated Expiration
- 2033-12-28
AI Technical Summary
When existing ultrasound imaging and ultrasound therapy modules are combined, it is difficult to meet functional needs, especially when the therapeutic transducer is small in size, making it difficult to implement an effective combination.
Design an integrated ultrasound therapy and imaging probe that integrates a therapeutic transducer and an imaging transducer on the rod, allowing it to work independently and accurately treat and image patients through the treatment focus.
The integration of diagnosis, treatment and monitoring in small spaces (such as the esophagus, nasal cavity, vagina, uterus, rectum, blood vessels, etc.) has been achieved, improving the accuracy and reliability of treatment.
Smart Images
Figure CN222427019U_ABST
Abstract
Description
Technical Field
[0001] The utility model belongs to the technical field of medical equipment, in particular to an integrated ultrasonic treatment and imaging probe. Background Art
[0002] FUS (Focused Ultrasound) technology focuses ultrasound waves in a focal area in space to generate high energy density, thereby achieving heating and destruction of local biological tissues. FUS technology is widely used in the medical field. As a non-invasive physical therapy technology, FUS provides more advanced clinical treatment options for many diseases. During FUS treatment, the ultrasound waves emitted by the treatment transducer are focused in the body to form a focus, and then a series of biological effects (thermal effect, mechanical effect, cavitation effect, etc.) are generated at the focus to achieve the purpose of treating or intervening in the disease. In order to ensure the accuracy of FUS treatment, it is particularly important to monitor its focal position and treatment process. Therefore, most FUS treatment systems need to be equipped with medical imaging modules; due to the obvious advantages of ultrasound imaging in terms of cost-effectiveness, real-time capability and compatibility, ultrasound imaging has become one of the most important guidance and monitoring methods in FUS treatment.
[0003] There are two main ways to integrate the two modules of ultrasound imaging and ultrasound therapy. First, design an ultrasound transducer that can be used for both imaging and treatment (dual-mode transducer). The advantage of the dual-mode transducer is that it has a simple structure and unique spatial coordinates for treatment and imaging, which eliminates the spatial registration process of the two. However, the performance of the dual-mode transducer is difficult to take into account the two different application requirements of treatment and imaging, and the two modes cannot work at the same time. Therefore, the existing ultrasound-guided FUS system generally adopts the second method, that is, the ultrasound imaging transducer and the ultrasound therapy transducer are designed separately and then combined in space. When combining the therapy transducer and the imaging transducer in space, the two main goals are: (1) the imaging area is large enough to represent the anatomical relationship between the target treatment area and the surrounding organs or tissues in the image; (2) the focus of the therapy transducer must be within the coverage of the ultrasound imaging to ensure that the imaging module can guide, locate and monitor the therapy module. At present, the most commonly used combination method is that the imaging transducer and the therapy transducer have overlapping and intersecting axes in space.
[0004] Although both the axis coincidence and axis intersection combinations are widely used clinically, they are only suitable for larger therapeutic transducers. If the two transducers for imaging and treatment are coaxially combined, it is generally necessary to dig out a part of the space in the central area of the emitting surface of the therapeutic transducer to place the detachable or integrated imaging transducer. Obviously, if the therapeutic transducer itself is small in size, this method is difficult to implement. For the combination of intersecting axes, the existing design generally requires placing a transducer in each direction, which has high requirements on space availability and is only suitable for in vitro FUS treatment scenarios supported by larger ultrasonic therapeutic transducers. Utility Model Content
[0005] In view of the above-mentioned shortcomings of the prior art, the purpose of the present invention is to provide an integrated ultrasound therapy and imaging probe to solve the problem in the prior art that the combination of ultrasound imaging and ultrasound therapy modules cannot meet functional requirements.
[0006] In order to achieve the above-mentioned purpose and other related purposes, the technical solution of the utility model is as follows:
[0007] An integrated ultrasonic treatment and imaging probe, comprising:
[0008] A rod, wherein the rod is a hollow structure, and an opening is provided on the side of the front end of the rod;
[0009] A therapeutic transducer, the therapeutic transducer is arranged at the front of the rod and located in the hollow structure, the geometric focusing axis of the therapeutic transducer is located on one side of the rod, and emits acoustic energy from the opening of the rod, and has a therapeutic focus in the geometric focusing axis;
[0010] An imaging transducer is arranged at the front part of the rod and located in the hollow structure, and an imaging area of the imaging transducer covers the treatment focus.
[0011] Optionally, the rod is a cylindrical or polygonal column structure, and the axial diameter of the rod can remain consistent or gradually change in the axial direction.
[0012] Optionally, the diameter of the rod is 2 mm-10 mm.
[0013] Optionally, the therapeutic transducer is a single element or a phased array and faces the opening.
[0014] Optionally, the geometric focusing axis of the therapeutic transducer is perpendicular to the central axis of the rod, and the energy output of the therapeutic transducer is 1-100W.
[0015] Optionally, the array of imaging transducers is inclined to the central axis of the rod, and the imaging transducer is located on one side of the therapeutic transducer.
[0016] Optionally, the imaging transducers are distributed on both sides of the therapeutic transducer, and the imaging areas of the imaging transducers on both sides do not overlap.
[0017] Optionally, the array of the imaging transducer is a linear array or a convex array, and the number of array elements of the imaging array of the imaging transducer is 32-128.
[0018] Optionally, the rod has a cavity outside the opening, the cavity is filled with degassed water, the outside of the cavity is wrapped with a sound-permeable material, the sound-permeable material seals the degassed water, and the cavity is connected to a circulating water device.
[0019] Accordingly, the utility model also provides a cavity FUS treatment system, comprising:
[0020] An integrated ultrasound therapy and imaging probe, any of the above integrated ultrasound therapy and imaging probes;
[0021] The system host comprises an ultrasonic treatment module, an ultrasonic imaging module and a control module. The ultrasonic treatment module is electrically connected to the treatment transducer, the ultrasonic imaging module is electrically connected to the imaging transducer, the ultrasonic treatment module and the ultrasonic imaging module are both electrically connected to the control module, and the control module is connected to an image display.
[0022] In the present invention, the integrated ultrasonic treatment and imaging probe and the cavity FUS treatment system are connected by a fixed cable or a plug-in connector, and the treatment transducer and the imaging transducer are integrated on the rod. The treatment transducer works independently to emit the treatment focus, and the imaging transducer works independently to perform imaging to cover the treatment focus, so that the patient can be accurately treated through the treatment focus. The mutual coordination of treatment and imaging in this solution realizes accurate and reliable focused ultrasound ablation, and realizes the integration of diagnosis, treatment, and monitoring in a small space (such as the esophagus, nasal cavity, vagina, uterus, rectum, blood vessels, etc.). Compared with the prior art, in this solution, the integrated ultrasonic treatment and imaging probe is used to combine the treatment transducer and the imaging transducer together and drive them independently. When used, they cooperate with each other to effectively and accurately complete the treatment of the patient. BRIEF DESCRIPTION OF THE DRAWINGS
[0023] Figure 1 This is a schematic structural diagram of an exemplary integrated ultrasound therapy and imaging probe of the present invention;
[0024] Figure 2 4 is a system diagram of an exemplary cavity FUS treatment system of the present invention.
[0025] The description of the reference numerals in the embodiments includes:
[0026] Rod 10, hollow structure 11, opening 12, cavity 13, sound-transmitting material 14,
[0027] Therapeutic transducer 20, geometric focusing axis 21, therapeutic focus 22,
[0028] Imaging transducer 30 , imaging area 31 . DETAILED DESCRIPTION
[0029] In the following description, a large number of specific details are given to provide a more thorough understanding of the utility model. However, it is obvious to those skilled in the art that the utility model can be implemented without one or more of these details. In other examples, in order to avoid confusion with the utility model, some technical features known in the art are not described.
[0030] It should be understood that the utility model can be implemented in different forms and should not be construed as being limited to the embodiments presented herein. On the contrary, providing these embodiments will make the disclosure thorough and complete, and fully convey the scope of the utility model to those skilled in the art. In the accompanying drawings, the same reference numerals represent the same components throughout.
[0031] In the present invention, the integrated ultrasound treatment and imaging probe is a part of the cavity FUS treatment system. The cavity FUS treatment system includes a system host. Figure 2 As shown, the system host includes an ultrasonic treatment module, an ultrasonic imaging module and a control module. The ultrasonic treatment and imaging integrated probe is connected to the system host through a fixed cable or a plug-in connector. The ultrasonic treatment and imaging integrated probe integrates a treatment transducer 20 and an imaging transducer 30. The ultrasonic treatment module is electrically connected to the treatment transducer 20, the ultrasonic imaging module is electrically connected to the imaging transducer 30, and both the ultrasonic treatment module and the ultrasonic imaging module are electrically connected to the control module, and the control module is connected to an image display. The system host provides energy and controls the treatment transducer 20 and the imaging transducer 30 through cables to meet the needs of doctors; wherein, the ultrasonic treatment and imaging integrated probe can be the ultrasonic treatment and imaging integrated probe of any of the following embodiments.
[0032] Specifically, in the actual implementation process, in order to cooperate with the use of the integrated ultrasound therapy and imaging probe, a control system is designed in the system host to meet the mutual coordination of treatment and imaging and realize accurate and reliable focused ultrasound ablation. In this control system, ultrasound imaging and monitoring algorithms are used to obtain the location information and treatment progress of the target treatment area, but are not limited to a certain algorithm; the image information obtained by the ultrasound imaging module will be transmitted to the control module and the image display module. The control module can analyze the image information and make decisions to adjust the treatment (such as changing the treatment position, adjusting the treatment time, treatment power and other related parameters), and provide real-time feedback to the ultrasound therapy module for execution. The system host can be designed to be handheld portable or desktop, and can be plugged and unplugged with different models of the above-mentioned integrated ultrasound therapy and imaging probes.
[0033] The specific structure of the ultrasonic treatment and imaging integrated probe in the utility model is shown in FIG. Figure 1 The integrated ultrasound therapy and imaging probe includes:
[0034] A rod 10, wherein the rod 10 is a hollow structure 11, and an opening 12 is provided on the side of the front end of the rod 10;
[0035] A therapeutic transducer 20, wherein the therapeutic transducer 20 is disposed at the front of the rod 10 and is located in the hollow structure 11, wherein a geometric focusing axis 21 of the therapeutic transducer 20 is located at one side of the rod 10, and emits acoustic energy from an opening 12 of the rod 11, and has a therapeutic focus 22 in the geometric focusing axis;
[0036] An imaging transducer 30 is disposed at the front portion of the rod 10 and located in the hollow structure 11 . An imaging region 31 of the imaging transducer 30 covers the treatment focus 22 .
[0037] The main function of the imaging transducer 30 is to guide, locate and monitor the treatment area, and the imaging area 31 thereof is a plane area with narrow edges, and the imaging area 31 needs to cover the treatment focus 22. For the rod 10, the end for inserting into the patient's body is the front end or front part of the rod 10, and the end held by the doctor is the rear end or rear part of the rod 10. In order to describe the positions of the arrangement of other related structures, reference is made to the rod 10 for description.
[0038] In the actual implementation process, the treatment transducer 20 and the imaging transducer 30 are integrated on the rod 10. The treatment transducer 20 works independently to emit ultrasonic waves focused at the treatment focus 22, and the imaging transducer 30 works independently to perform imaging to cover the treatment focus 22. The two are integrated on one probe, which is convenient for doctors to carry out FUS treatment in the patient's body cavity 13 (such as rectal, vaginal, nasal, etc.) or blood vessels, and can accurately treat the patient through the treatment focus 22.
[0039] In some embodiments, the rod 10 is a cylindrical or polygonal structure, and the axial diameter of the rod 10 can remain consistent or change gradually in the axial direction. Figure 1 As shown, the overall structure of the rod 10 is a cylindrical or multi-prism structure, which is convenient for entering the patient's body cavity, such as the esophagus, nasal cavity, vagina, uterus, rectum, blood vessels and the like; the rod 10 can also be plate-shaped or cubic-strip-shaped, and the outer diameter in the axial direction of the rod 10 can remain consistent, or it can gradually change in the axial direction, that is, the outer diameter along the axial direction of the rod 10 gradually decreases or increases from one end of the rod 10 to the other end; the outer part of the rod 10 can also be wavy in the axial direction, as long as it can be convenient for entering the patient's body cavity.
[0040] In some embodiments, the diameter of the rod 10 is 2 mm to 10 mm. Figure 1 As shown, the size and structure of the rod 10 can realize the integration of diagnosis, treatment and monitoring in a small space (such as the esophagus, nasal cavity, vagina, uterus, rectum, blood vessels, etc.).
[0041] In some embodiments, the therapeutic transducer 20 is a single element or a phased array and is directed toward the opening 12. For example, Figure 1 As shown, the geometric dimensions, focal depth, focusing gain and other parameters of the therapeutic transducer 20 can be adjusted according to the probe body size and specific application requirements.
[0042] In some embodiments, the geometric focusing axis 21 of the therapeutic transducer 20 is perpendicular to the central axis of the rod 10, and the energy output of the therapeutic transducer 20 is 1-100 W. For example, Figure 1 As shown, the treatment focus 22 is located on the geometric focusing axis 21 for implementing the treatment process. The geometric focusing axis 21 is perpendicular to the central axis of the rod 10 for convenient control. In fact, the geometric focusing axis 21 can also be tilted within a certain range.
[0043] In some embodiments, the array of the imaging transducer 30 is inclined to the central axis of the rod 10, and the imaging transducer 30 is located on one side of the therapeutic transducer 20. For example, Figure 1As shown, the imaging transducer 30 is located at the right side ① or the left side ② of the therapeutic transducer 20 and is tilted to ensure that the imaging area 31 of the imaging transducer 30 covers the therapeutic focus 22 .
[0044] In some embodiments, the imaging transducers 30 are distributed on both sides of the therapeutic transducer 20, and the imaging areas 31 of the imaging transducers 30 on both sides do not overlap. Figure 1 As shown, the imaging transducers 30 are disposed at the left and right sides (① and ②) of the therapeutic transducer 20, and the imaging areas 31 of the imaging transducers 30 at the two locations do not overlap, which can enhance the imaging effect.
[0045] In some embodiments, the array of the imaging transducer 30 is a linear array or a convex array, and the number of array elements of the imaging array of the imaging transducer 30 is 32-128. Figure 1 As shown, different imaging beamforming methods can be applied to the transducer.
[0046] In some embodiments, the rod 10 has a cavity 13 outside the opening 12, the cavity 13 is filled with degassed water, the cavity 13 is wrapped with a sound-permeable material 14 outside, the sound-permeable material 14 seals the degassed water, and the cavity 13 is connected to a circulating water device. For example, Figure 1 As shown, in order to ensure good coupling between ultrasound and human tissue, the area where the rod 10 contacts the human tissue is filled with degassed water (this structure can be discarded for intravascular applications), and the degassed water is sealed with a sound-permeable material 14. The cavity 13 of the degassed water is connected to a circulating water device. The cavity 13 is on the side of the rod 10 close to the opening 12. At the opening 12, the cavity 13 is formed and sealed by the sound-permeable material 14, and the cavity 13 is filled with degassed water.
[0047] The above embodiments are merely illustrative of the principles and effects of the present invention, and are not intended to limit the present invention. Anyone familiar with the technology may modify or alter the above embodiments without departing from the spirit and scope of the present invention. Therefore, all equivalent modifications or alterations made by a person of ordinary skill in the art without departing from the spirit and technical concept disclosed in the present invention shall still be covered by the claims of the present invention.
Claims
1. An integrated ultrasonic treatment and imaging probe, characterized in that: include: A rod, wherein the rod is a hollow structure, and an opening is provided on the side of the front end of the rod; A therapeutic transducer, the therapeutic transducer is arranged at the front of the rod and located in the hollow structure, the geometric focusing axis of the therapeutic transducer is located on one side of the rod, and emits acoustic energy from the opening of the rod, and has a therapeutic focus in the geometric focusing axis; An imaging transducer is arranged at the front part of the rod and located in the hollow structure, and an imaging area of the imaging transducer covers the treatment focus.
2. The integrated ultrasonic therapy and imaging probe according to claim 1, characterized in that: The rod is a cylindrical or polygonal column structure, and the axial diameter of the rod can remain consistent or change gradually in the axial direction.
3. The integrated ultrasonic therapy and imaging probe according to claim 1, characterized in that: The diameter of the rod is 2mm-10mm.
4. The integrated ultrasonic therapy and imaging probe according to claim 1, characterized in that: The therapeutic transducer is a single array element or a phased array and faces the opening.
5. The integrated ultrasonic therapy and imaging probe according to claim 1, characterized in that: The geometric focusing axis of the therapeutic transducer is perpendicular to the central axis of the rod, and the energy output of the therapeutic transducer is 1-100W.
6. The integrated ultrasonic therapy and imaging probe according to claim 5, characterized in that: The array of the imaging transducer is inclined to the central axis of the rod, and the imaging transducer is located on one side of the therapeutic transducer.
7. The integrated ultrasonic therapy and imaging probe according to claim 5, characterized in that: The imaging transducers are distributed on both sides of the therapeutic transducer, and the imaging areas of the imaging transducers on both sides do not overlap.
8. The integrated ultrasonic therapy and imaging probe according to claim 1, characterized in that: The array of the imaging transducer is a linear array or a convex array, and the number of array elements of the imaging array of the imaging transducer is 32-128.
9. The integrated ultrasonic therapy and imaging probe according to any one of claims 1 to 7, characterized in that: The rod is provided with a cavity outside the opening, the cavity is filled with degassed water, the outside of the cavity is wrapped with a sound-permeable material, the sound-permeable material seals the degassed water, and the cavity is connected to a circulating water device.
10. A cavity FUS treatment system, characterized in that: include: An integrated ultrasound therapy and imaging probe, the integrated ultrasound therapy and imaging probe according to any one of claims 1 to 9; The system host comprises an ultrasonic treatment module, an ultrasonic imaging module and a control module. The ultrasonic treatment module is electrically connected to the treatment transducer, the ultrasonic imaging module is electrically connected to the imaging transducer, the ultrasonic treatment module and the ultrasonic imaging module are both electrically connected to the control module, and the control module is connected to an image display.