Kit for early diagnosis of susceptibility genes

Abstract

The utility model discloses an early diagnosis susceptibility gene kit, which comprises a kit base body for installation, a box cover rotatably connected to the upper end of the kit base body, a cushioning layer and a connecting rod, the cushioning layer is fixedly installed on the inner side of the kit base body, and an installation plate and an installation block are arranged in the cushioning layer. The mounting block is fixedly connected to the inner side of the rear section of the kit base body, the connecting rod is mounted on the front side of the mounting plate, the mounting plate is mounted in the front section of the kit base body, the kit cover is connected with the mounting plate through the connecting rod, and a detection table and a storage box are fixedly mounted at the upper ends of the left section and the right section of the mounting plate respectively. According to the kit for early diagnosis of the susceptibility genes, the position of a specimen in the kit can be fixed, falling and damage caused by displacement of the specimen are effectively avoided when the kit is carried, the specimen can be conveniently and rapidly taken out during diagnosis, the working time is saved, the detection table is pulled to move upwards when the kit cover is unfolded, and diagnosis work can be conveniently carried out.

Description

Technical Field

[0001] The utility model relates to the technical field of melanoma diagnosis, in particular to an early diagnosis susceptibility gene kit. Background Art

[0002] Malignant melanoma, also known as melanoma, is the most aggressive skin cancer with a high incidence rate. The number of deaths caused by melanoma accounts for the highest proportion of all skin cancers. Inhibiting the invasive growth and metastasis of melanoma cells has become an important focus of research on treatment strategies. PAF15 is closely related to the development of melanoma and can significantly inhibit cell proliferation. PAF15 can be used as a marker for diagnosing melanoma.

[0003] For example, the utility model with the authorization announcement number CN210479407U provides a susceptibility gene kit for early diagnosis of malignant melanoma, including a box body, a rotating body and a storage area are arranged in the box body, a main motor is arranged at the bottom of the rotating body, a storage tube is arranged in the rotating body, a grinding tube is inserted in the storage tube, an ultraviolet lamp is arranged at the top of the storage area, a storage hole is arranged inside the storage area, and a drawer is arranged at the bottom of the storage area. The kit provided by the utility model has a compact design and is easy to transfer. It can provide a specimen processing environment for melanoma detection in a timely manner, can reduce the specimen's contact with other genes, reduce the probability of specimen contamination, slow down the sample degradation rate, improve the accuracy and stability of the detection, ensure the efficiency of the test, and has wide applicability in the medical field;

[0004] However, the above technical solution still has some disadvantages. The specimen lacks a fixed limiting structure inside the reagent kit, and is easily displaced when the reagent kit is transported, causing damage to the specimen, affecting the diagnosis work and the leakage of melanoma reagents. Therefore, we propose an early diagnosis susceptibility gene kit to solve the above problems. Utility Model Content

[0005] The utility model aims to provide a kit for early diagnosis of susceptible genes, so as to solve the problem raised in the above-mentioned background technology that the specimen currently lacks a fixed limiting structure inside the kit, and is prone to displacement during transportation of the kit, causing damage to the specimen, affecting the development of diagnosis and leakage of melanoma reagents.

[0006] To achieve the above object, the utility model provides the following technical solution: an early diagnosis susceptibility gene kit, comprising: a kit base for installation and a box cover rotatably connected to the upper end of the kit base;

[0007] Also includes:

[0008] A shock absorbing layer, wherein the shock absorbing layer is fixedly mounted on the inner side of the reagent kit base, and a mounting plate and a mounting block are arranged inside the shock absorbing layer, and the mounting block is fixedly connected to the inner side of the rear section of the reagent kit base;

[0009] A connecting rod, the connecting rod is installed on the front side of the mounting plate, and the mounting plate is installed inside the front section of the reagent box base, and the box cover is connected to the mounting plate through the connecting rod, and the upper ends of the left and right sections of the mounting plate are respectively fixedly mounted with a detection table and a storage box;

[0010] A driving sleeve, wherein the driving sleeve is mounted on the outside of the mounting sleeve, and sliders are fixedly mounted on the front and rear sides of the lower end of the mounting sleeve, and a limiting sleeve is arranged on the outside of the driving sleeve, and the outer end of the limiting sleeve is fixedly connected to the mounting block;

[0011] The clamping plate is arranged on the left and right sides of the specimen, and a swing rod is installed at the middle outer end of the clamping plate, and a second spring is fixedly installed at the outer end of the clamping plate, and the specimen is arranged on the inner side of the mounting tube.

[0012] Preferably, the upper end of the connecting rod is rotatably connected to the inner side of the box cover, and the lower end of the connecting rod is fixedly connected to a cylindrical protrusion, and the protrusion is slidably connected to the inside of a groove opened at the front end of the mounting plate.

[0013] Preferably, the groove at the front end of the mounting plate is in an "L"-shaped structure, and the left and right ends of the mounting plate are slidably connected to the inner side of the limit plate, and the limit plate is fixedly installed on the inner side of the shock-absorbing layer, and blocks are provided under the left and right sections of the mounting plate.

[0014] Preferably, the block is slidably connected to the inner side of the test kit base and the upper section of the shock-absorbing layer, and a first spring is sleeved on the outer side of the middle part of the block, and the two ends of the first spring are respectively fixedly connected, the inner end of the block is arranged in an inclined structure, and the outer end of the block is rotatably connected to a pull rod, and the pull rod is connected to the rotating shaft of the first spring through a torsion spring.

[0015] Preferably, the driving sleeve is rotatably connected to the inner side of the limiting sleeve, and the upper end of the driving sleeve protrudes above the mounting block, and vertical through grooves are provided at both the front and rear ends of the driving sleeve, and the slider is slidably connected inside the through groove of the driving sleeve.

[0016] Preferably, the mounting tube is rotatably connected to the inner side of the driving sleeve through a slider, and the inner side of the lower end of the mounting tube is an arc-shaped structure, and an elastic pad is fixedly installed on the inner side of the lower end of the mounting tube, and the outer section of the slider is slidably connected to the spiral through groove opened inside the limiting sleeve.

[0017] Preferably, the middle part of the swing rod is rotatably connected to the mounting tube, and the upper end of the swing rod is rotatably connected to the clamping plate, and an elastic pad is fixedly installed on the inner end of the clamping plate, the clamping plate is symmetrically arranged along the central axis of the specimen, and the end of the second spring away from the clamping plate is fixedly connected to the inner wall of the mounting tube.

[0018] Compared with the prior art, the utility model has the following beneficial effects: the early diagnosis susceptibility gene kit can fix the position of the specimen inside the kit, effectively avoid the specimen from falling off and being damaged due to displacement when the kit is carried, and facilitate the rapid removal of the specimen during diagnosis, saving working time, and pull the detection table upward when the box cover is unfolded, facilitating the diagnosis work;

[0019] 1. A connecting rod and a stopper are provided. When the box cover is opened, the connecting rod is pulled to swing, and the connecting rod slides in the groove inside the mounting plate, so that the mounting plate moves up with the rotation of the box cover, and the detection table and the storage box are higher than the test kit base. Then, the position of the mounting plate is limited by the support of the stopper and the engagement of the lower end protrusion of the connecting rod with the mounting plate, which is convenient for the diagnosis of melanoma and simple to operate;

[0020] 2. A driving sleeve, a mounting sleeve and a limiting sleeve are provided. The driving sleeve is rotated to move the slider by using the through grooves at the front and rear parts thereof. When the slider slides, the mounting sleeve is driven to move. When the slider is driven by the driving sleeve to slide in the spiral groove inside the limiting sleeve, the mounting sleeve moves up with the slider and rises above the driving sleeve, which is convenient for quick access to the specimen. The specimen is stored inside the mounting sleeve to avoid the position movement of the reagent kit during transportation, avoid the damage of the specimen, and prevent safety accidents;

[0021] 3. A swing rod, a clamping plate and a second spring are provided. The clamping plate firmly fixes the specimen on the inner side of the mounting tube by the thrust provided by the second spring, and the elastic pad at the inner end of the clamping plate plays a buffering and protective role while increasing the friction. The swing rod protruding from the mounting tube can be rotated by pressing the upper end of the swing rod to pull the clamping plate away from the specimen, and the specimen can be pulled up to be taken out. The operation is simple, and the position of the fixed specimen is limited. In addition, the clamping plate is suitable for specimens of different diameters. BRIEF DESCRIPTION OF THE DRAWINGS

[0022] Figure 1 This is a schematic diagram of the front cross-sectional structure of the utility model;

[0023] Figure 2 This is a schematic diagram of the cross-sectional structure of the utility model from top view;

[0024] Figure 3 This is a schematic diagram of the front cross-sectional structure of the installation tube of the utility model;

[0025] Figure 4 This is a schematic diagram of the overall structure of the drive sleeve of the utility model;

[0026] Figure 5 This is a schematic diagram of the overall structure of the limiting sleeve of the utility model;

[0027] Figure 6 For this utility model Figure 1 Enlarged structural diagram at A in the middle.

[0028] In the figure: 1. reagent box base; 2. box cover; 3. shock-absorbing layer; 4. connecting rod; 5. mounting plate; 6. limiting plate; 7. block; 8. first spring; 9. pull rod; 10. testing table; 11. storage box; 12. mounting block; 13. specimen; 14. driving sleeve; 15. mounting cylinder; 16. slider; 17. limiting sleeve; 18. swing rod; 19. clamping plate; 20. second spring. DETAILED DESCRIPTION

[0029] The following will be combined with the drawings in the embodiments of the utility model to clearly and completely describe the technical solutions in the embodiments of the utility model. Obviously, the described embodiments are only part of the embodiments of the utility model, not all of the embodiments. Based on the embodiments in the utility model, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the utility model.

[0030] See also Figure 1-6 The utility model provides a technical solution: an early diagnosis susceptibility gene test kit, comprising: a test kit base 1, a box cover 2, a shock absorbing layer 3, a connecting rod 4, a mounting plate 5, a limiting plate 6, a stopper 7, a first spring 8, a pull rod 9, a detection table 10, a storage box 11, a mounting block 12, a specimen 13, a driving sleeve 14, a mounting cylinder 15, a slider 16, a limiting sleeve 17, a swing rod 18, a clamping plate 19 and a second spring 20.

[0031] When using the early diagnosis susceptibility gene kit, first Figure 1 , Figure 2 and Figure 6 As shown, the shock-absorbing layer 3 is fixedly installed on the inner side of the reagent box base 1, the box cover 2 is rotatably connected to the upper end of the reagent box base 1, and the inner side of the box cover 2 is rotatably connected to the upper end of the connecting rod 4, and a cylindrical protrusion is fixedly installed on the rear side of the lower end of the connecting rod 4, and the protrusion is movably connected to the inside of the groove opened at the front end of the mounting plate 5, and the groove at the front end of the mounting plate 5 is in an "L"-shaped structure, the left and right ends of the mounting plate 5 are slidably connected to the inner side of the limit plate 6, and the limit plate 6 is fixedly installed on the inner side of the front section of the shock-absorbing layer 3, and stoppers 7 are provided under the left and right sections of the mounting plate 5;

[0032] When the box cover 2 is rotated to open, the box cover 2 pulls the connecting rod 4 to swing, and the connecting rod 4 slides in the groove on the inner side of the mounting plate 5, and the mounting plate 5 is pulled by the connecting rod 4 to slide on the inner side of the limit plate 6. When the mounting plate 5 is pulled to the uppermost end of the limit plate 6 by the connecting rod 4, the protrusion at the lower end of the connecting rod 4 is stuck in the lower end of the groove of the mounting plate 5, and when the mounting plate 5 moves up, it contacts the stopper 7;

[0033] The stopper 7 is slidably connected to the inner side of the reagent kit base 1 and the upper section of the shock absorbing layer 3, and a first spring 8 is sleeved on the outer side of the middle part of the stopper 7, and the two ends of the first spring 8 are fixedly connected to the reagent kit base 1 and the stopper 7, respectively. The inner end of the stopper 7 is arranged in an inclined structure, and the outer end of the stopper 7 is rotatably connected to a pull rod 9, and the pull rod 9 is connected to the rotating shaft of the first spring 8 through a torsion spring. The detection table 10 and the storage box 11 are fixedly mounted on the left and right sections of the upper end of the mounting plate 5, respectively.

[0034] When the mounting plate 5 contacts the inclined surface of the block 7, the block 7 is squeezed to slide into the shock-absorbing layer 3, and the first spring 8 is squeezed to undergo elastic deformation. As the mounting plate 5 moves upward, the block 7 loses the obstruction, and the first spring 8 recovers its elastic deformation to push the block 7 to reset. The mounting plate 5 is supported by the block 7 to prevent it from being displaced and affecting the normal diagnosis work. Subsequently, the PAF15 reagent is taken out from the storage box 11 and the detection and diagnosis work is performed on the top of the testing table 10. When the mounting plate 5 is folded up, the connecting rod 4 is pushed upward to move the protrusion up to the horizontal groove, the pull rod 9 is rotated to expand it to be level with the block 7, and the pull rod 9 is pulled outward to make the block 7 leave the bottom of the mounting plate 5, and the mounting plate 5 is lowered to complete the folding work.

[0035] like Figure 1 , Figure 2 , Figure 3 , Figure 4 and Figure 5 As shown, the mounting block 12 is fixedly connected to the inner side of the rear section of the reagent box base 1, and the specimen 13 is arranged inside the mounting block 12, and the specimen 13 is mounted on the inner side of the mounting tube 15, and the driving sleeve 14 is sleeved on the outer side of the mounting tube 15, and the upper end of the driving sleeve 14 protrudes above the mounting block 12, and the front and rear ends of the driving sleeve 14 are provided with vertical through grooves, and the front and rear ends of the lower end of the mounting tube 15 are fixedly installed with sliders 16, and the sliders 16 are slidably connected inside the through grooves of the driving sleeve 14, and the driving sleeve 14 is rotatably connected to the outer side of the mounting tube 15 through the sliders 16, and the driving sleeve 14 is rotatably connected to the inner side of the limiting sleeve 17, and the outer end of the limiting sleeve 17 is fixedly connected to the mounting block 12, and the outer section of the slider 16 is slidably connected to the spiral through groove provided inside the limiting sleeve 17;

[0036] The specimen 13 is stored inside the mounting tube 15. When the specimen 13 needs to be taken out, the upper end of the driving sleeve 14 is rotated. At this time, the through groove inside the driving sleeve 14 drives the slider 16 to move. While the outer section of the slider 16 slides inside the limiting sleeve 17, the slider 16 slides inside the driving sleeve 14. The mounting tube 15 is driven by the slider 16 to rotate and move upward until the slider 16 is stuck at the turning point of the upper end of the through groove of the driving sleeve 14. The mounting tube 15 drives the specimen 13 to move above the mounting block 12, which is convenient for taking the specimen 13. The operation is simple and convenient for quickly taking and placing the specimen 13. The specimen 13 is stored inside the mounting block 12 to protect the safety of the specimen 13 and provide a heat preservation function for the specimen 13.

[0037] The clamping plate 19 is symmetrically mounted on the left and right sides of the upper section of the specimen 13, and an elastic pad is fixedly mounted on the inner end of the clamping plate 19, and a second spring 20 is fixedly mounted on the outer end of the clamping plate 19, and one end of the second spring 20 away from the clamping plate 19 is fixedly connected to the inner wall of the mounting tube 15, and a swing rod 18 is rotatably connected to the middle part of the outer end of the clamping plate 19, and the middle part of the swing rod 18 is rotatably connected to the specimen 13, and the lower end of the specimen 13 is supported by the elastic pad on the inner side of the lower end of the mounting tube 15, and the inner side of the lower end of the mounting tube 15 is an arc-shaped structure;

[0038] When the specimen 13 is stored inside the mounting tube 15, the elastic pad at the lower end of the mounting tube 15 acts as a shock absorber to protect the safety of the specimen 13. The second spring 20 provides thrust for the clamping plate 19, and the clamping plate 19 is used to firmly clamp the specimen 13. The elastic pad at the inner end of the clamping plate 19 acts as a buffer and protects while increasing the friction to prevent the specimen 13 from moving when the reagent kit is transported, thereby avoiding damage to the specimen 13 and the occurrence of safety accidents. At the same time, the shock-absorbing layer 3 plays a shock-absorbing role. When the specimen 13 is transmitted to the top, the part of the swing rod 18 protruding from the mounting tube 15 is pressed to rotate it. The upper end of the swing rod 18 pulls the clamping plate 19 outward, and the clamping plate 19 squeezes the second spring 20 to cause elastic deformation. The specimen 13 loses the squeezing of the clamping plate 19 and can be easily lifted and taken away.

[0039] The contents not described in detail in this specification belong to the prior art known to professional and technical personnel in this field. In addition, the directional terms such as up, down, left, right, front, and back in the text only represent their relative positions rather than absolute positions.

[0040] The standard parts used in the utility model can all be purchased from the market, and special-shaped parts can be customized according to the instructions and the drawings. The specific connection methods of each part adopt the conventional means such as mature bolts, rivets, welding, etc. in the existing technology. The machinery, parts and equipment all adopt the conventional models in the existing technology, and the circuit connection adopts the conventional connection method in the existing technology, which will not be described in detail here.

[0041] Although the present invention has been described in detail with reference to the aforementioned embodiments, those skilled in the art may still modify the technical solutions described in the aforementioned embodiments, or make equivalent substitutions for some of the technical features therein. Any modifications, equivalent substitutions, improvements, etc. made within the spirit and principles of the present invention shall be included in the protection scope of the present invention.

Claims

1. A kit for early diagnosis of susceptibility genes, comprising: A reagent box base (1) for installation and a box cover (2) rotatably connected to the upper end of the reagent box base (1); It is characterized by further comprising: A shock absorbing layer (3), the shock absorbing layer (3) is fixedly mounted on the inner side of the reagent kit base (1), and a mounting plate (5) and a mounting block (12) are arranged inside the shock absorbing layer (3), and the mounting block (12) is fixedly connected to the inner side of the rear section of the reagent kit base (1); A connecting rod (4), wherein the connecting rod (4) is mounted on the front side of a mounting plate (5), and the mounting plate (5) is mounted inside the front section of the reagent box base (1), and the box cover (2) is connected to the mounting plate (5) via the connecting rod (4), and the upper ends of the left and right sections of the mounting plate (5) are respectively fixedly mounted with a detection table (10) and a storage box (11); A driving sleeve (14), wherein the driving sleeve (14) is mounted on the outside of the mounting sleeve (15), and sliders (16) are fixedly mounted on both sides of the front and rear ends of the lower end of the mounting sleeve (15), and a limiting sleeve (17) is arranged on the outside of the driving sleeve (14), and the outer end of the limiting sleeve (17) is fixedly connected to the mounting block (12); A clamping plate (19) is arranged on the left and right sides of the specimen (13), and a swing rod (18) is installed at the middle outer end of the clamping plate (19), and a second spring (20) is fixedly installed at the outer end of the clamping plate (19), and the specimen (13) is arranged on the inner side of the mounting tube (15).

2. The early diagnosis susceptibility gene kit according to claim 1, characterized in that: The upper end of the connecting rod (4) is rotatably connected to the inner side of the box cover (2), and the lower end of the connecting rod (4) is fixedly connected to a cylindrical protrusion, and the protrusion is slidably connected to the inside of a groove opened at the front end of the mounting plate (5).

3. The early diagnosis susceptibility gene kit according to claim 2, characterized in that: The groove at the front end of the mounting plate (5) is in an "L"-shaped structure, and the left and right ends of the mounting plate (5) are slidably connected to the inner side of the limit plate (6), and the limit plate (6) is fixedly mounted on the inner side of the shock absorbing layer (3), and stoppers (7) are provided below the left and right sections of the mounting plate (5).

4. The early diagnosis susceptibility gene kit according to claim 3, characterized in that: The block (7) is slidably connected to the inner side of the upper section of the reagent box base (1) and the shock-absorbing layer (3), and a first spring (8) is sleeved on the outer side of the middle part of the block (7), and the two ends of the first spring (8) are fixedly connected to (1) and the block (7), respectively. The inner end of the block (7) is arranged in an inclined structure, and the outer end of the block (7) is rotatably connected to a pull rod (9), and the pull rod (9) is connected to the rotating shaft of the first spring (8) through a torsion spring.

5. The early diagnosis susceptibility gene kit according to claim 1, characterized in that: The driving sleeve (14) is rotatably connected to the inner side of the limiting sleeve (17), and the upper end of the driving sleeve (14) protrudes above the mounting block (12), and vertical through grooves are provided at both the front and rear ends of the driving sleeve (14), and the sliding block (16) is slidably connected inside the through groove of the driving sleeve (14).

6. The early diagnosis susceptibility gene kit according to claim 5, characterized in that: The mounting tube (15) is rotatably connected to the inner side of the driving sleeve (14) via a slider (16), and the inner side of the lower end of the mounting tube (15) is an arc-shaped structure, and an elastic pad is fixedly installed on the inner side of the lower end of the mounting tube (15), and the outer section of the slider (16) is slidably connected to a spiral through groove provided inside the limiting sleeve (17).

7. The early diagnosis susceptibility gene kit according to claim 1, characterized in that: The middle part of the swing rod (18) is rotatably connected to the mounting tube (15), and the upper end of the swing rod (18) is rotatably connected to the clamping plate (19), and an elastic pad is fixedly installed on the inner end of the clamping plate (19), the clamping plate (19) is symmetrically arranged along the central axis of the specimen (13), and one end of the second spring (20) away from the clamping plate (19) is fixedly connected to the inner wall of the mounting tube (15).

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