Concave pyramid microneedle
By designing the microneedle with a concave pyramid structure, the contradiction between the hardness and puncture effect of traditional microneedles is solved, and better puncture and drug delivery effect is achieved.
Patent Information
- Application Number
- CN202421021643.X
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- Filing Date
- 2024-05-13
- Publication Date
- 2025-02-21
- Estimated Expiration
- 2034-05-13
AI Technical Summary
While ensuring hardness, existing microneedles are difficult to improve the puncture effect, resulting in a small contact area with the tissue fluid after puncture and poor drug delivery effect.
A concave pyramid microneedle was designed. By changing the side of the traditional quadric pyramid-shaped microneedle to a concave surface, the contact area is reduced, the puncture effect is improved, and the microneedle patch is prepared by the reverse mold method to ensure the uniformity and strength of the microneedle. .
On the basis of ensuring structural strength, the concave pyramid microneedle reduces the contact area, improves the puncture effect and drug delivery effect, making the contact area with the tissue fluid after puncture larger, accelerates the dissolution rate, and better drug delivery effect.
Smart Images
Figure CN222510625U_ABST
Abstract
Description
Technical Field
[0001] The utility model relates to the technical field of microneedle patches, in particular to a concave pyramid microneedle. Background Art
[0002] Microcrystal patches are made by molding, stretching and other methods. The method of using microcrystal patches is to use the transdermal technology of microcrystal arrays to allow the cosmetic-related active ingredients or drugs on the backing of the patch to break through the stratum corneum, penetrate into the skin and dissolve the active ingredients, thereby achieving the desired effect.
[0003] Currently, most of the microneedles on the market are regular cones such as tetrahedrons, hexagonal pyramids, octagonal pyramids, and cones. There is a contradiction between the sharpness and hardness of the needle body. If the needle is too thin, the piercing effect is good, but the hardness is not enough and it is easy to break; if the needle is thick, the hardness is enough, the piercing effect is not strong, and the effect of breaking through the stratum corneum is not good. Utility Model Content
[0004] The purpose of the utility model is to provide a concave pyramid microneedle to solve the problem of how to ensure the hardness of the microneedle while improving the puncture effect.
[0005] Technical solution: The utility model provides a concave pyramid microneedle, including: a microneedle patch, the microneedle patch includes a plurality of microneedles and a fixed backing, the microneedles are evenly distributed on the fixed backing, the microneedles are in the shape of a quadrangular pyramid, and the four sides of the microneedle are concave. While ensuring the structural strength of the traditional quadrangular pyramid microneedle, the four sides are changed to concave, which can reduce the contact area, improve the puncture effect, and increase the contact area with the tissue fluid after puncture, so as to achieve better drug delivery effect.
[0006] Furthermore, the above-mentioned concave pyramid microneedle, the microneedle patch is prepared by a reverse molding method.
[0007] Furthermore, the concave pyramid microneedles are arranged in an array to ensure uniform distribution and drug delivery.
[0008] Furthermore, the above-mentioned concave pyramid microneedle is made of soluble material and can be dissolved by contact with tissue fluid after puncture.
[0009] Furthermore, the above-mentioned concave pyramid microneedle contains an effective ingredient.
[0010] Furthermore, the above-mentioned concave pyramid microneedle has a specification of 0.1-1 mm in width and 0.3-3 mm in length.
[0011] Furthermore, in the above-mentioned concave pyramid microneedle, the width of the microneedle tip is 0.01-0.05 mm.
[0012] It can be seen from the above technical scheme that the utility model has the following beneficial effects: the concave pyramid microneedle described in the utility model has a simple structure and is easy to manufacture. The microneedle is made into a concave quadrangular pyramid structure, which not only ensures the strength of the microneedle, but also reduces the contact area. Under the same pressure, the pressure is increased, so that the puncture effect of the microneedle is better, the contact area with the tissue fluid after puncture is larger, and the dissolution effect is better. BRIEF DESCRIPTION OF THE DRAWINGS
[0013] Figure 1 This is a schematic diagram of a concave pyramid microneedle of the utility model;
[0014] Figure 2 This is a top view of the microneedle patch of the utility model;
[0015] Figure 3 It is a schematic diagram of the three-dimensional structure of the microneedle of the utility model.
[0016] In the figure: microneedle patch 1, microneedle 11. DETAILED DESCRIPTION
[0017] Example 1
[0018] like Figure 1-3 A concave pyramid microneedle is shown, comprising: a microneedle patch 1, wherein the microneedle patch 1 comprises a plurality of microneedles 11 and a fixed backing, wherein the microneedles 11 are evenly distributed on the fixed backing, and the microneedles 11 are in the shape of a quadrangular pyramid, and the four sides of the microneedle 11 are concave. While ensuring the structural strength of the traditional quadrangular pyramid, the four sides of the quadrangular pyramid microneedle 11 are changed into concave surfaces, which can reduce the contact area, achieve better puncture effect, and increase the contact area with tissue fluid after puncture, thereby accelerating the dissolution rate and achieving better drug administration effect.
[0019] like Figure 3 A concave pyramid microneedle is shown, wherein the concave surface of the microneedle 11 has a bending radius of 0.41 mm; the specifications of the microneedle 11 are 0.28 mm in width and 0.9 mm in length; and the needle tip of the microneedle 11 is 0.02 mm wide.
[0020] Example 2
[0021] On the basis of Example 1, in this example, Figure 1-2 A concave pyramid microneedle is shown, wherein the microneedles 11 are distributed in an array arrangement.
[0022] In this embodiment, the microneedle patch 1 is prepared by a reverse molding method.
[0023] In this embodiment, the microneedle 11 is made of soluble material, which can be dissolved by contacting with tissue fluid after puncture, and the microneedle 11 contains active ingredients such as drugs. After breaking through the stratum corneum of the skin, the active ingredients in the microneedle 11 penetrate into the skin and dissolve, achieving the expected effect.
[0024] It should be noted that the above is only a technical solution of the utility model and is not a limitation. Although the utility model is described in detail with reference to the preferred embodiments, a person skilled in the art should understand that the technical solution of the utility model can be modified or replaced by equivalents without departing from the scope of the technical solution of the utility model, which should be included in the scope of the claims of the utility model.
Claims
1. A concave pyramid microneedle, characterized in that: include: A microneedle patch (1) comprises a plurality of microneedles (11) and a fixed backing, wherein the microneedles (11) are evenly distributed on the fixed backing, the microneedles (11) are in the shape of a quadrangular pyramid, and the four side surfaces around the microneedles (11) are concave surfaces.
2. A concave pyramid microneedle according to claim 1, characterized in that: The microneedle patch (1) is prepared by a molding method.
3. A concave pyramid microneedle according to claim 1, characterized in that: The microneedles (11) are distributed in an array arrangement.
4. The concave pyramid microneedle according to claim 1, characterized in that: The microneedle (11) is made of a soluble material and can dissolve when in contact with tissue fluid after puncture.
5. The concave pyramid microneedle according to claim 1, characterized in that: The microneedle (11) contains a drug component.
6. The concave pyramid microneedle according to claim 1, characterized in that: The microneedle (11) has a width of 0.1-1 mm and a length of 0.3-3 mm.
7. A concave pyramid microneedle according to claim 6, characterized in that: The needle tip width of the microneedle (11) is 0.01-0.05 mm.