Immunohistochemical equipment

By introducing ultrasonic cleaning tanks and lifting components into the immunohistochemistry equipment, automatic cleaning and drying of slides is achieved, solving the problems of cumbersome operation and slow detection speed of existing equipment, and improving work efficiency.

CN222529365UActive Publication Date: 2025-02-25HUNAN HECHUANGSI MEDICAL TECH CO LTD
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Patent Information

Application Number
CN202421016437.X
Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
Filing Date
2024-05-11
Publication Date
2025-02-25
Estimated Expiration
2034-05-11

AI Technical Summary

Technical Problem

Existing immunohistochemistry equipment cannot automatically clean the slides, and requires manual cleaning, and automatic drying cannot be achieved, resulting in cumbersome operations, wasted manpower and material resources, and delayed detection speed.

Method used

An immunohistochemistry device is designed, including an ultrasonic cleaning tank and lifting assembly, capable of automatically cleaning slides and automatic drying through a thermostat.

Benefits of technology

Automatic cleaning and drying of slides is realized, manual operation is reduced, detection speed is improved, and manpower and material resources are saved.

✦ Generated by Eureka AI based on patent content.

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Abstract

The utility model discloses immunohistochemical equipment, which relates to the technical field of medical treatment, and comprises a box body, the top of the box body movably abuts against a box cover, one side of the inner bottom wall of the box body is movably connected with a waste water barrel, and the other side of the inner bottom wall of the box body is fixedly connected with a fixed table. A water purifying barrel is movably connected to one side of the top of the fixing table, a cover plate is movably connected to the top end of the water purifying barrel, one side of the cover plate is fixedly connected to the inner wall of the box body, a thermostat is fixedly connected to the upper end face of the cover plate, and a cleaning assembly used for cleaning glass slides is arranged on the inner wall of the box body. A fixing assembly for fixing a bottle body is arranged on the inner wall of the box body, the cleaning assembly can be used for placing slides in an ultrasonic cleaning pool for cleaning, and the temperature in the box body can be increased through a thermostat after cleaning is completed, so that water on a slide group is evaporated, the detection speed can be effectively increased, repeated manual operation is avoided, and the detection efficiency is improved. And the fixing assembly is beneficial to storage and observation of the reagent bottles.
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Description

Technical Field

[0001] The utility model relates to the technical field of medical treatment, in particular to an immunohistochemical device. Background Art

[0002] Immunohistochemistry is the application of the basic principle of immunology - antigen-antibody reaction, that is, the principle of specific binding of antigen and antibody. It uses chemical reaction to make the color developer of labeled antibody develop color to determine the antigen in tissue cells, and conduct localization, qualitative and relative quantitative research on it. This is called immunohistochemistry or immunocytochemistry.

[0003] Most of the existing immunohistochemistry equipment cannot automatically clean the slides and need to be cleaned manually, which is cumbersome and troublesome, and wastes manpower and material resources. At the same time, after the slides are cleaned, they need to be dried manually to evaporate the moisture on the slides. Automatic drying cannot be completed, which slows down the detection speed.

[0004] Based on this, an immunohistochemistry device is now provided, which can eliminate the disadvantages of the existing devices. Utility Model Content

[0005] The utility model aims to provide an immunohistochemistry device to solve the problems in the background technology.

[0006] In order to achieve the above purpose, the utility model provides the following technical solutions:

[0007] An immunohistochemical device comprises a box body, the top of the box body is movably abutted with a box cover, one side of the inner bottom wall of the box body is movably connected with a waste water bucket, the other side of the inner bottom wall of the box body is fixedly connected with a fixed platform, one side of the top of the fixed platform is movably connected with a clean water bucket, the top of the clean water bucket is movably connected with a cover plate, one side of the cover plate is fixedly connected to the inner wall of the box body, and the upper end surface of the cover plate is fixedly connected with a thermostat;

[0008] A cleaning component for cleaning the slide is arranged on the inner wall of the box;

[0009] The inner wall of the box is provided with a fixing assembly for fixing the bottle body.

[0010] On the basis of the above technical solutions, the present invention also provides the following optional technical solutions:

[0011] In an optional solution: the cleaning component includes an ultrasonic cleaning pool, one side of the ultrasonic cleaning pool is fixedly connected to the inner wall of the box body, a water inlet is opened on the side of the box body close to the clean water bucket, and a water inlet pipe is movably connected in the water inlet, a first solenoid valve is arranged on the water inlet pipe, and the other end of the water inlet pipe is fixedly connected to the clean water bucket, a water outlet is opened on the side of the ultrasonic cleaning pool close to the waste water bucket, and a water outlet pipe is movably connected in the water outlet, a second solenoid valve is fixedly connected to the water outlet pipe, and the other end of the water outlet pipe is fixedly connected to the waste water bucket;

[0012] A lifting component for lifting the object to be cleaned is arranged on one side of the ultrasonic cleaning tank close to the box body.

[0013] In an optional scheme: the lifting assembly includes a fixing bar, two of the fixing bars are fixedly connected to one side of the box body, a support column is fixedly connected between the two fixing bars, a reciprocating screw is arranged on the side between the two fixing bars away from the support column, a guide block is slidably connected to the outer surface of the support column, the reciprocating screw is threadedly connected to the guide block, a glass slide plate is fixedly connected to one side of the guide block, a glass slide group is fixedly connected to the upper end surface of the glass slide plate, a motor is fixedly connected to the lower end surface of the fixing bar, the output end of the motor passes through the fixing bar and is fixedly connected to the bottom end of the reciprocating screw, and the bottom end of the motor is fixedly connected to the upper end surface of the fixed platform.

[0014] In an optional solution: the fixing component includes a fixing plate, which is arranged above the waste water barrel and fixedly connected to the inner wall of the box body, and a plurality of reagent slots are provided on the fixing plate. A placement plate is arranged above the fixing plate, and the placement plate is fixedly connected to the box body, and a plurality of reagent holes are provided on the placement plate, and reagent bottles are stored in the reagent holes.

[0015] In an optional solution: a groove corresponding to the waste water bucket and the clean water bucket is opened on the side of the box body away from the fixing bar, and a door is arranged in the groove, and a handle is arranged on the door.

[0016] In an optional solution, a plurality of slide sets are provided.

[0017] In an optional solution: the box cover is L-shaped.

[0018] In an optional solution: the handle is in an arc shape.

[0019] Compared with the prior art, the beneficial effects of the present invention are as follows:

[0020] 1. The utility model can lift the glass slide plate and the glass slide group up and down through the lifting component, so as to realize the cleaning of the glass slide group, and the process does not require manual operation, which is convenient and trouble-free.

[0021] 2. The utility model uses a cleaning component to place the glass slide in an ultrasonic cleaning tank for cleaning. After cleaning, the temperature in the box can be increased by a thermostat to evaporate the moisture on the glass slide group, which can effectively speed up the detection speed and avoid repeated manual operations;

[0022] 3. The utility model achieves the goal of securing the reagent bottle on the fixing table and the placement plate by means of the fixing assembly, thereby preventing the reagent bottle from falling during storage or observation. BRIEF DESCRIPTION OF THE DRAWINGS

[0023] Figure 1 It is a structural schematic diagram of the utility model.

[0024] Figure 2 It is a schematic diagram of the cutaway structure of the utility model.

[0025] Figure 3 It is a partial structural schematic diagram of the utility model.

[0026] Among them: 1. Box body; 2. Box cover; 3. Waste water bucket; 4. Fixed table; 5. Clean water bucket; 6. Cover plate; 7. Thermostat; 8. Ultrasonic cleaning pool; 9. Water inlet pipe; 10. First solenoid valve; 11. Water outlet pipe; 12. Second solenoid valve; 13. Fixed bar; 14. Support column; 15. Reciprocating screw rod; 17. Guide block; 19. Glass slide plate; 20. Glass slide group; 21. Motor; 22. Fixed plate; 23. Placement plate. DETAILED DESCRIPTION

[0027] The following will be combined with the drawings in the embodiments of the utility model to clearly and completely describe the technical solutions in the embodiments of the utility model. Obviously, the described embodiments are only part of the embodiments of the utility model, not all of the embodiments. Based on the embodiments in the utility model, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the utility model.

[0028] Example 1

[0029] See also Figure 1-Figure 3 In an embodiment of the utility model, an immunohistochemical device comprises a box body 1, the top of the box body 1 is movably abutted with a box cover 2, one side of the inner bottom wall of the box body 1 is movably connected with a waste water bucket 3, the other side of the inner bottom wall of the box body 1 is fixedly connected with a fixed platform 4, one side of the top of the fixed platform 4 is movably connected with a clean water bucket 5, the top of the clean water bucket 5 is movably connected with a cover plate 6, one side of the cover plate 6 is fixedly connected to the inner wall of the box body 1, and the upper end surface of the cover plate 6 is fixedly connected with a thermostat 7;

[0030] A cleaning component for cleaning the slide is provided on the inner wall of the box 1;

[0031] The inner wall of the box body 1 is provided with a fixing assembly for fixing the bottle body.

[0032] In one embodiment, Figure 3 As shown, the cleaning component includes an ultrasonic cleaning tank 8, one side of which is fixedly connected to the inner wall of the box body 1, a water inlet is provided on the side of the box body 1 close to the clean water bucket 5, and a water inlet pipe 9 is movably connected in the water inlet, a first solenoid valve 10 is provided on the water inlet pipe 9, and the other end of the water inlet pipe 9 is fixedly connected to the clean water bucket 5, a water outlet is provided on the side of the ultrasonic cleaning tank 8 close to the waste water bucket 3, and a water outlet pipe 11 is movably connected in the water outlet, a second solenoid valve 12 is fixedly connected to the water outlet pipe, and the other end of the water outlet pipe 11 is fixedly connected to the waste water bucket 3; by opening the first solenoid valve 10, the liquid in the clean water bucket 5 is put into the ultrasonic cleaning tank 8, so that the ultrasonic cleaning tank 8 is filled with liquid, and after the ultrasonic cleaning tank 8 finishes cleaning the object, the first solenoid valve 10 is closed, and the second solenoid valve 12 is started, and the waste water flows into the waste water bucket 3 through the water pipe;

[0033] The ultrasonic cleaning tank 8 is provided with a lifting assembly for lifting the object to be cleaned on one side close to the box body 1 .

[0034] In one embodiment, Figure 3 As shown, the lifting assembly includes a fixing bar 13, two of the fixing bars 13 are fixedly connected to one side of the box body 1, a support column 14 is fixedly connected between the two fixing bars 13, a reciprocating screw rod 15 is arranged on the side away from the support column 14 between the two fixing bars 13, the outer surface of the support column 14 is slidably connected with a guide block 17, the reciprocating screw rod 15 is threadedly connected to the guide block 17, one side of the guide block 17 is fixedly connected with a glass plate 19, the upper end surface of the glass plate 19 is fixedly connected with a glass slide group 20, the lower end surface of the fixing bar 13 is fixedly connected with a motor 21, the output end of the motor 21 passes through the fixing bar 13 and is fixedly connected to the bottom end of the reciprocating screw rod 15, and the bottom end of the motor 21 is fixedly connected to the upper end surface of the fixed platform 4; by starting the motor 21, the reciprocating screw rod 15 is driven to move, and at the same time, the reciprocating screw rod 15 drives the guide block 17 to move up and down, and the guide block drives the glass plate 19 to move, thereby realizing the up and down lifting of the glass plate 19.

[0035] In one embodiment, Figure 2 and Figure 3As shown, the fixing assembly includes a fixing plate 22, which is arranged above the waste water bucket 3 and fixedly connected to the inner wall of the box body 1. A plurality of reagent slots are provided on the fixing plate 22. A placement plate 23 is provided above the fixing plate 22, which is fixedly connected to the box body 1 and provided with a plurality of reagent holes, in which reagent bottles are stored. The grooves provided on the fixing plate 22 can fix the reagent bottles to prevent the bottoms thereof from swaying left and right, and at the same time, the placement plate 23 stabilizes the reagent bottles inside it to prevent the upper and middle parts of the reagent bottles from swaying.

[0036] In one embodiment, Figure 1 As shown, a groove corresponding to the waste water bucket 3 and the clean water bucket 5 is opened on the side of the box body 1 away from the fixing bar 13, and a door is arranged in the groove, and a handle is arranged on the door; it is convenient for checking the internal situation of the equipment, and at the same time, the waste water bucket 3 and the clean water bucket 5 can also be taken out.

[0037] Example 2

[0038] In one embodiment, Figure 3 As shown, the slide set 20 is provided in plurality, and multiple samples can be detected simultaneously.

[0039] In one embodiment, Figure 1 As shown, the box cover 2 is L-shaped, ensuring that bacteria are prevented from falling in during detection.

[0040] In one embodiment, Figure 1 As shown, the handle is in an arc shape, which conforms to the curvature of the experimenter's hand, and the curved arc prevents sharp collisions from occurring between experimental instruments.

[0041] The working principle of the utility model is as follows: the above embodiment discloses an immunohistochemical device, wherein the box cover 2 is opened, after opening, the motor 21 is started, and the motor 21 drives the reciprocating screw rod 15 and the guide block 17 to move up and down, so that the glass slide plate 19 and the glass slide group 20 can be lowered into the ultrasonic cleaning tank 8 for cleaning. After the glass slide plate 19 and the glass slide group 20 are placed in the ultrasonic cleaning tank 8, the first solenoid valve 10 is opened, and the liquid in the clean water bucket 5 flows into the ultrasonic cleaning tank 8 through the water inlet pipe 9. After the liquid in the ultrasonic cleaning tank 8 reaches a certain preset value, the first solenoid valve 10 is closed, and then the glass slide group 20 is cleaned. After the cleaning is completed, the second solenoid valve is opened. 12, make the waste water in the ultrasonic cleaning pool 8 flow into the waste water bucket 3 through the outlet pipe 11, after the glass slide plate 19 and the glass slide group 20 are raised to a position flush with the upper surface of the placement plate 23, turn on the thermostat 7, after the temperature in the box body 1 rises, the water on the glass slide group 20 is evaporated, and then the temperature of the thermostat 7 can be adjusted to a preset value, and then the liquid or object to be tested can be manually placed on the glass slide group 20, and the box cover 2 can be closed for testing. At the same time, when the reagent bottle needs to be stored under constant temperature conditions or needs to be observed, the reagent bottle can be placed on the placement plate 20 and the fixing plate 19 to stabilize the reagent bottle and prevent it from falling and shaking left and right.

[0042] The above is only a specific implementation of the present application, but the protection scope of the present application is not limited thereto. Any person skilled in the art who is familiar with the present technical field can easily think of changes or substitutions within the technical scope disclosed in the present application, which should be included in the protection scope of the present application. Therefore, the protection scope of the present application should be based on the protection scope of the claims.

Claims

1. An immunohistochemistry device, comprising a housing (1), characterized in that: The top of the box body (1) is movably abutted against a box cover (2); one side of the inner bottom wall of the box body (1) is movably connected to a waste water bucket (3); the other side of the inner bottom wall of the box body (1) is fixedly connected to a fixed platform (4); one side of the top of the fixed platform (4) is movably connected to a clean water bucket (5); the top of the clean water bucket (5) is movably connected to a cover plate (6); one side of the cover plate (6) is fixedly connected to the inner wall of the box body (1); and the upper end surface of the cover plate (6) is fixedly connected to a thermostat (7); A cleaning component for cleaning a glass slide is arranged on the inner wall of the box (1); A fixing assembly for fixing the bottle body is arranged on the inner wall of the box body (1).

2. An immunohistochemistry device according to claim 1, characterized in that: The cleaning assembly comprises an ultrasonic cleaning pool (8), one side of the ultrasonic cleaning pool (8) is fixedly connected to the inner wall of the box body (1), a water inlet is provided on a side of the box body (1) close to the clean water bucket (5), and a water inlet pipe (9) is movably connected to the water inlet, a first solenoid valve (10) is provided on the water inlet pipe (9), and the other end of the water inlet pipe (9) is fixedly connected to the clean water bucket (5), a water outlet is provided on a side of the ultrasonic cleaning pool (8) close to the waste water bucket (3), and a water outlet pipe (11) is movably connected to the water outlet, a second solenoid valve (12) is fixedly connected to the water outlet pipe (11), and the other end of the water outlet pipe (11) is fixedly connected to the waste water bucket (3); A lifting component for lifting the object to be cleaned is arranged on one side of the ultrasonic cleaning tank (8) close to the box body (1).

3. An immunohistochemistry device according to claim 2, characterized in that: The lifting assembly comprises a fixing bar (13), two fixing bars (13) are fixedly connected to one side of the box body (1), a support column (14) is fixedly connected between the two fixing bars (13), a reciprocating screw rod (15) is arranged on the side away from the support column (14) between the two fixing bars (13), a guide block (17) is slidably connected to the outer surface of the support column (14), the reciprocating screw rod (15) is threadedly connected to the guide block (17), a glass plate (19) is fixedly connected to one side of the guide block (17), the upper end surface of the glass plate (19) is fixedly connected to a glass slide group (20), and a plurality of glass slide groups (20) are arranged, the lower end surface of the fixing bar (13) is fixedly connected to a motor (21), the output end of the motor (21) passes through the fixing bar (13) and is fixedly connected to the bottom end of the reciprocating screw rod (15), and the bottom end of the motor (21) is fixedly connected to the upper end surface of the fixed platform (4).

4. The immunohistochemistry device according to claim 1, characterized in that: The fixing assembly comprises a fixing plate (22), the fixing plate (22) being arranged above the waste water bucket (3), and the fixing plate (22) being fixedly connected to the inner wall of the box body (1), the fixing plate (22) being provided with a plurality of reagent grooves, a placement plate (23) being arranged above the fixing plate (22), the placement plate (23) being fixedly connected to the box body (1), and the placement plate (23) being provided with a plurality of reagent holes, and reagent bottles being stored in the reagent holes.

5. The immunohistochemistry device according to claim 1, characterized in that: A groove corresponding to the waste water bucket (3) and the clean water bucket (5) is provided on a side of the box body (1) away from the fixing bar (13), and a door is provided in the groove, and a handle is provided on the door.

6. The immunohistochemistry device according to claim 1, characterized in that: The box cover (2) is L-shaped.

7. The immunohistochemistry device according to claim 5, characterized in that: The handle is in an arc shape.