High-low temperature ablation needle with balloon and ablation equipment

Abstract

The embodiment of the utility model relates to the technical field of cryotherapy, in particular to a high-low temperature ablation needle with a balloon and ablation equipment, which comprise a puncture probe, a rewarming component, the balloon, a liquid inlet tube, an air return tube and a vacuum tube, the vacuum tube is connected with the puncture probe, and the liquid inlet tube and the air return tube sequentially penetrate through the vacuum tube from inside to outside; the rewarming assembly is connected with the puncture probe; the puncture probe is provided with a liquid inlet hole and a liquid outlet hole which are communicated with each other; the air return pipe communicates with the liquid outlet hole and is used for outputting the ablation working medium; the balloon is arranged on the puncture probe in a sleeving mode and communicated with the liquid outlet hole. The balloon is additionally arranged on the puncture probe, under the condition that the basic effect of the ablation needle is not affected, the balloon body is made to be well attached to a cavity tumor by means of the expansibility of the balloon, cold energy can be better transmitted, and through the combination of the vacuum tube and the balloon in the two freezing structures, the ablation needle can be used for ablation. Therefore, the product can be better suitable for various operation scenes.

Description

Technical Field

[0001] The embodiments of the utility model relate to the technical field of low-temperature cryotherapy, and in particular to a high-low temperature ablation needle with a balloon and an ablation device. Background Art

[0002] Currently, the cryoablation technology for treating tumors is developing very rapidly. It mainly uses refrigeration technology for cooling, or directly uses the cold energy of cryogenic working fluids to cryotherapy the target tissue. The former is represented by gas throttling refrigeration technology, and the latter is represented by liquid nitrogen direct freezing technology.

[0003] The cryoablation system using gas throttling technology is represented by the argon-helium knife, which realizes the freezing and thawing treatment process through argon throttling cooling and helium throttling heating. This system is easier to implement because the gas is at room temperature before throttling. However, in order to ensure the treatment effect, it is necessary to configure a high-pressure gas source with a higher safety risk level (for example, up to 40MPa), which makes transportation and storage inconvenient and the cost is high.

[0004] The liquid nitrogen cryoablation system directly pressurizes low-temperature liquid nitrogen and delivers it to the ablation needle, and then freezes the tumor through the endothermic evaporation of liquid nitrogen. The rewarming process can be heated by anhydrous ethanol vapor or by radio frequency, microwave, etc. Since liquid nitrogen is easier to obtain and has a lower temperature, the pressure during use is much lower than that of gas throttling technology (about 0.3MPa-0.5MPa), so it has better economy and applicability.

[0005] The current liquid nitrogen cryoablation system is represented by the "hot and cold knife", which is mainly used for surgical puncture and cryotherapy of solid tumors. It is not very effective in the treatment of hollow tumors, so there is an urgent need for a cryoablation system that is compatible with both hollow tumors and solid tumors. Utility Model Content

[0006] The embodiment of the utility model provides a high-low temperature ablation needle with a balloon, comprising: a puncture probe, a rewarming component, a balloon, a liquid inlet tube, an air return tube and a vacuum tube;

[0007] The vacuum tube is connected to the puncture probe, and the liquid inlet pipe and the air return pipe are sequentially arranged in the vacuum tube from the inside to the outside;

[0008] The rewarming component is connected to the puncture probe;

[0009] The puncture probe is provided with a liquid inlet and a liquid outlet which are interconnected;

[0010] The liquid inlet pipe is connected to the liquid inlet hole and is used for inputting ablative working fluid;

[0011] The air return pipe is in communication with the liquid outlet hole and is used for outputting the ablative working fluid;

[0012] The balloon is sleeved on the puncture probe and is communicated with the liquid outlet.

[0013] Based on the above scheme, it can be known that when the ablation needle is not in use (no fluid is introduced), the balloon will be in a contracted state. When in use, liquid nitrogen is introduced into the liquid inlet tube, and the liquid nitrogen flows out from the liquid outlet. Most of the liquid nitrogen exchanges cold with the outside, turns into nitrogen and flows back from the return air tube. A small part of the liquid nitrogen enters the balloon, exchanges cold with the balloon surface, and turns into nitrogen and flows back from the return air tube. The continuous liquid nitrogen fluid ensures the stability of the balloon's external dimensions, and it can also be understood that the balloon is opened due to pressure. During surgery, the balloon can fit the cavity tumor well and achieve better cold transfer, making the product better suitable for a variety of surgical scenarios.

[0014] In a feasible solution, the liquid inlet is located at the top of the puncture probe close to one end of the vacuum tube, and the liquid outlet is located on the side wall of the puncture probe and corresponds to the position of the balloon, so as to increase the fluid flow performance.

[0015] In a feasible solution, a plurality of the liquid outlet holes are provided, and the plurality of the liquid outlet holes are evenly arranged along the axial direction of the puncture probe.

[0016] In a feasible solution, along the axial direction of the puncture probe, the radius from both ends of the balloon to the center gradually increases.

[0017] In a feasible solution, a reflective layer and / or a heat absorbing layer is provided outside the return air pipe, wherein the reflective layer is used to reflect light and heat radiation, and the heat absorbing layer is used to absorb heat.

[0018] In a feasible solution, the rewarming component includes a metal rod and a wire, and the wire is inserted into the liquid inlet pipe;

[0019] The metal rod is arranged in the vacuum tube and contacts the puncture probe, and the wire is wound around the metal rod to realize eddy current heating of the puncture probe.

[0020] In a feasible solution, the rewarming assembly includes: a head end electrode, a tail end electrode, a wire and a connecting ring;

[0021] The connecting ring is arranged between the head end electrode and the tail end electrode to insulate and isolate the head end electrode and the tail end electrode;

[0022] The wires are connected to the head end electrode and the tail end electrode respectively to achieve bipolar heating of the puncture probe.

[0023] In a feasible solution, the high and low temperature ablation needle further includes: a handle, a transmission vacuum tube and a plug-in connector;

[0024] The proximal end of the handle is connected to the vacuum tube, the distal end is connected to the transmission vacuum tube, and the liquid inlet tube is in communication with the transmission vacuum tube;

[0025] The plug-in connector is arranged at the far end of the transmission vacuum tube and is used for connecting the ablative working medium.

[0026] An embodiment of the utility model further provides an ablation device, comprising the high and low temperature ablation needle described in any one of the above feasible solutions. BRIEF DESCRIPTION OF THE DRAWINGS

[0027] In order to more clearly illustrate the embodiments of the utility model or the technical solutions in the prior art, the drawings required for use in the embodiments or the description of the prior art will be briefly introduced below. Obviously, the drawings described below are some embodiments of the utility model. For ordinary technicians in this field, other drawings can be obtained based on these drawings without paying creative labor.

[0028] Figure 1 Schematic diagram of the high and low temperature ablation needle in the first embodiment of the present invention Figure 1 ;

[0029] Figure 2 This is a partial cross-sectional view of the high and low temperature ablation needle in the first embodiment of the utility model;

[0030] Figure 3 Schematic diagram of the high and low temperature ablation needle in the first embodiment of the present invention Figure 2 ;

[0031] Figure 4 This is a schematic diagram of a high and low temperature ablation needle in the second embodiment of the present utility model;

[0032] Figure 5 This is a schematic diagram of the high and low temperature ablation needle in the third embodiment of the present utility model.

[0033] Numbers in the figure:

[0034] 1. Puncture probe; 101. Liquid outlet; 2. Balloon; 3. Vacuum tube; 4. Handle; 5. Transmission vacuum tube; 6. Connector; 7. Heat absorption layer; 8. Reflection layer; 9. Air return pipe; 10. Liquid inlet pipe; 11. Wire; 12. Metal rod; 13. Front electrode; 14. Connecting ring; 15. Tail electrode. DETAILED DESCRIPTION

[0035] The inventor of the present application has found that there are at least the following problems in the prior art:

[0036] (1) The front end structure of the existing high- and low-temperature ablation needle is a stainless steel probe structure, which is convenient for puncturing the epidermis and entering the tumor location in the body. It can effectively target solid tumors, but it is not suitable for hollow tumors. Since the transfer of cold requires a solid medium to achieve better and faster cooling, the gas in the hollow tumor will affect the transfer of cold and cannot effectively achieve cryoablation of the tumor.

[0037] (2) The rewarming of existing high and low temperature ablation needles is mostly a thawing process. There is no good high temperature to kill cancer cells again. Anhydrous ethanol is generally used as the rewarming medium. Anhydrous ethanol is a flammable gas and has certain risks. There is also the problem of needing to add alcohol regularly. Using alcohol for rewarming also requires heating the entire cooled pipeline to transfer heat to the front end of the product, which takes a long time and will also extend the subsequent freezing time.

[0038] (3) When the high- and low-temperature ablation needle is currently undergoing high-temperature rewarming, heat is easily transferred to the catheter surface, resulting in the problem of heat transfer to undesirable areas.

[0039] In order to make the purpose, technical solution and advantages of the embodiment of the utility model clearer, the technical solution in the embodiment of the utility model will be clearly and completely described below in conjunction with the drawings in the embodiment of the utility model. Obviously, the described embodiment is a part of the embodiment of the utility model, not all of the embodiments. Based on the embodiment of the utility model, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the utility model.

[0040] In the description of the present invention, it should be understood that the terms "center", "longitudinal", "lateral", "up", "down", "front", "back", "left", "right", "vertical", "horizontal", "top", "bottom", "inside", "outside", "axial", "radial", "circumferential" and the like indicate orientations or positional relationships based on the orientations or positional relationships shown in the accompanying drawings, and are only for the convenience of describing the present invention and simplifying the description, and do not indicate or imply that the device or element referred to must have a specific orientation, be constructed and operated in a specific orientation, and therefore should not be understood as a limitation on the present invention.

[0041] In the present invention, unless otherwise clearly specified and limited, the terms "install", "connect", "connect", "fix" and the like should be understood in a broad sense, for example, it can be a fixed connection, a detachable connection, or an integral connection; it can be a mechanical connection, an electrical connection, or a communication connection; it can be a direct connection, or an indirect connection through an intermediate medium, it can be the internal connection of two elements or the interaction relationship between two elements, unless otherwise clearly defined. For ordinary technicians in this field, the specific meanings of the above terms in the present invention can be understood according to specific circumstances.

[0042] The following specific embodiments are used to describe the technical solution of the utility model in detail. The following specific embodiments can be combined with each other, and the same or similar concepts or processes may not be described in detail in some embodiments.

[0043] Embodiment 1

[0044] Figure 1 Schematic diagram of the high and low temperature ablation needle in the first embodiment of the present invention Figure 1 ; Figure 2 This is a partial cross-sectional view of the high and low temperature ablation needle in the first embodiment of the utility model; Figure 3 Schematic diagram of the high and low temperature ablation needle in the first embodiment of the present invention Figure 2 ;like Figure 1-3 As shown, the high-low temperature ablation needle with a balloon 2 of this embodiment includes: a puncture probe 1, a balloon 2, a rewarming component, a liquid inlet tube 10, an air return tube 9 and a vacuum tube 3.

[0045] Specifically, the vacuum tube 3 and the rewarming assembly are respectively connected to the puncture probe 1, and the liquid inlet pipe 10 and the air return pipe 9 are sequentially inserted into the vacuum tube 3 from the inside to the outside. In this embodiment, the vacuum tube 3, the liquid inlet pipe 10, and the air return pipe 9 are concentrically arranged. The rewarming assembly is electrically connected to the puncture probe 1 to make the puncture probe 1 heat up. The puncture probe 1 is provided with a liquid inlet hole and a liquid outlet hole 101 that are interconnected. The liquid inlet hole is located at the top of the puncture probe 1, and the liquid outlet hole 101 is located on the side wall of the puncture probe 1. The liquid inlet pipe 10 is connected to the liquid inlet hole for inputting fluid, and the air return pipe 9 is connected to the liquid outlet hole 101 for outputting fluid. Then the balloon 2 is mounted on the puncture probe 1 and connected to the liquid outlet hole 101.

[0046] Preferably, a plurality of liquid outlet holes 101 are provided, and the plurality of liquid outlet holes 101 are evenly arranged along the axial direction of the puncture probe, so that the liquid nitrogen is evenly output from the liquid outlet holes to gradually expand the balloon.

[0047] It is not difficult to find from the above content that when not in use (no fluid is introduced), the balloon 2 will be in a contracted state. When in use, liquid nitrogen is introduced into the liquid inlet pipe 10, and the liquid nitrogen flows out from the liquid outlet. Most of the liquid nitrogen exchanges cold with the outside and turns into nitrogen gas to flow back from the return pipe 9. A small part of the liquid nitrogen enters the balloon 2 and exchanges cold with the surface of the balloon 2. After turning into nitrogen gas, it also flows back from the return pipe 9. The continuous liquid nitrogen fluid ensures that the outer size of the balloon 2 is stable. It can also be understood that the balloon 2 is opened due to pressure. During the operation, the balloon body can fit the cavity tumor well and achieve better cold transfer.

[0048] Optionally, along the axial direction of the puncture probe, the radius of the balloon 2 from both ends to the center gradually increases to an elliptical shape, and the balloon 2 as a whole is in the shape of a cone at both ends and a cylindrical shape in the middle, which can reduce the resistance of entering and exiting the cavity and is easier to shape. In this way, the shape of the balloon 2 after opening is similar to an oblong ellipsoid, which is easier to fit the lesion, for example, it is easier to fit a cavity tumor.

[0049] In addition, the material of the balloon 2 is generally PA (Polyamide, thermoplastic linear polyamide). PA material not only has high mechanical strength, good toughness, high tensile and compressive strength, but also has excellent fatigue resistance. The parts can maintain their original mechanical strength after repeated bending. In addition, PA material also has the advantages of high softening point and heat resistance, smooth surface, good wear resistance, corrosion resistance, no inertia to biological erosion, good antibacterial and mildew resistance, electrical insulation, light weight of parts, etc.

[0050] In this embodiment, a reflective layer 8 and a heat-absorbing layer 7 are provided outside the return air pipe 9. The reflective layer 8 is used to reflect light and radiation, such as aluminum foil and other materials that can reflect light well. The heat-absorbing layer 7 is used to absorb heat, such as absorbent cotton, which can absorb residual heat well. Since the transfer of high temperature is different from the transfer of low temperature, in the transfer of high temperature, heat radiation, heat conduction and heat convection exist at the same time. The vacuum layer can well prevent heat conduction and heat convection, but it is difficult to prevent heat radiation. The added reflective layer 8 and heat-absorbing layer 7 can well prevent heat radiation, so that the surface temperature of the product remains normal.

[0051] In addition, the wire 11 is provided with an insulating sheath to improve safety.

[0052] like Figure 3As shown, the rewarming component of the high and low temperature ablation needle in this embodiment, specifically, the puncture probe 1 is provided with a metal rod 12, and the wire 11 is wound around the metal rod 12. That is, the eddy current principle is adopted, and the ablation device end provides a high-frequency alternating current to generate a rapidly changing magnetic field around the wire 11. The rapidly changing magnetic field generates an induced current inside the metal rod 12, which quickly generates heat. The heat generated inside the metal rod 12 is quickly transferred to the puncture probe 1 through the connection with the puncture probe 1, thereby achieving rapid, efficient and safe heating.

[0053] Embodiment 2

[0054] Figure 4 Schematic diagram of the high and low temperature ablation needle in the second embodiment of the present utility model, as shown in Figure 4 As shown, the second embodiment is a replacement of the first embodiment, and the difference is that in the second embodiment, the rewarming component of the high and low temperature ablation needle in this embodiment, specifically, the rewarming component includes: a wire 11, a head end electrode 13, a tail end electrode 15 and a connecting ring 14, the connecting ring 14 is arranged between the head end electrode 13 and the tail end electrode 15, and the two are insulated and isolated, and the wire 11 is connected to the head end electrode 13 and the tail end electrode 15 respectively. That is, the bipolar principle is adopted, the head end electrode 13 and the tail end electrode 15 are respectively connected to a wire 11, and the middle is connected and electrically isolated by the connecting ring 14, and the connecting ring 14 is an insulating material (such as ceramic, etc.), and the high-frequency current is emitted from the device end, flows into the head end electrode 13 through the wire 11, and generates a large amount of heat at the place where the head end electrode 13 contacts the tissue, so as to achieve rapid and safe temperature rise, and the current flows through the human tissue, and then returns to the wire 11 from the tail end electrode 15, and finally returns to the device end.

[0055] Embodiment 3

[0056] Figure 5 This is a schematic diagram of the high and low temperature ablation needle in the third embodiment of the utility model. The high and low temperature ablation needle also includes: a handle 4, a transmission vacuum tube 5 and a plug-in connector 6. The proximal end of the handle 4 is connected to the vacuum tube 3, and the distal end is connected to the transmission vacuum tube 5. The liquid inlet tube 10 is connected to the transmission vacuum tube 5. The plug-in connector 6 is arranged at the distal end of the transmission vacuum tube 5 for connecting the fluid.

[0057] In summary, the ablation needle has the following advantages:

[0058] (1) The scope of application of the product has been expanded. Without affecting the original use effect, cryoablation of cavity tumors has been added, which can adapt to more application scenarios;

[0059] (2) To achieve safer thermal insulation, and no unexpected temperature rise will occur during the use of the product;

[0060] (3) Faster, safer, and more controllable heating, avoiding heating of the entire pipeline, saving time, alternating between hot and cold, and better killing cancer cells.

[0061] Embodiment 4

[0062] This embodiment also provides an ablation device, which includes the high and low temperature ablation needle described in any of the above embodiments.

[0063] In the present invention, unless otherwise clearly specified and limited, a first feature being “on” or “under” a second feature may mean that the first feature and the second feature are in direct contact, or the first feature and the second feature are in indirect contact via an intermediate medium.

[0064] Moreover, the first feature being “above”, “above”, and “above” the second feature may mean that the first feature is directly above or obliquely above the second feature, or simply means that the first feature is higher in level than the second feature. The first feature being “below”, “below”, and “below” the second feature may mean that the first feature is directly below or obliquely below the second feature, or simply means that the first feature is lower in level than the second feature.

[0065] In the description of this specification, the description with reference to the terms "one embodiment", "some embodiments", "example", "specific example" or "some examples" etc. means that the specific features, structures, materials or characteristics described in conjunction with the embodiment or example are included in at least one embodiment or example of the utility model. In this specification, the schematic representations of the above terms do not necessarily refer to the same embodiment or example. Moreover, the specific features, structures, materials or characteristics described may be combined in any one or more embodiments or examples in a suitable manner. In addition, those skilled in the art may combine and combine the different embodiments or examples described in this specification and the features of the different embodiments or examples, without contradiction.

[0066] Finally, it should be noted that the above embodiments are only used to illustrate the technical solution of the utility model, rather than to limit it. Although the utility model has been described in detail with reference to the aforementioned embodiments, ordinary technicians in this field should understand that they can still modify the technical solutions recorded in the aforementioned embodiments, or replace some or all of the technical features therein with equivalents. However, these modifications or replacements do not make the essence of the corresponding technical solution deviate from the scope of the technical solution of the embodiments of the utility model.

Claims

1. A high and low temperature ablation needle with a balloon, characterized in that: include: Puncture probe, rewarming assembly, balloon, fluid inlet tube, gas return tube and vacuum tube; The vacuum tube is connected to the puncture probe, and the liquid inlet pipe and the air return pipe are sequentially arranged in the vacuum tube from the inside to the outside; The rewarming component is connected to the puncture probe; The puncture probe is provided with a liquid inlet and a liquid outlet which are interconnected; The liquid inlet pipe is connected to the liquid inlet hole and is used for inputting ablative working fluid; The air return pipe is in communication with the liquid outlet hole and is used for outputting the ablative working fluid; The balloon is sleeved on the puncture probe and is communicated with the liquid outlet.

2. The high and low temperature ablation needle according to claim 1, characterized in that: The liquid inlet hole is located at the top of the puncture probe close to one end of the vacuum tube, and the liquid outlet hole is located on the side wall of the puncture probe and corresponds to the position of the balloon.

3. The high and low temperature ablation needle according to claim 2, characterized in that: A plurality of the liquid outlet holes are provided, and the plurality of the liquid outlet holes are evenly arranged along the axial direction of the puncture probe.

4. The high and low temperature ablation needle according to claim 1, characterized in that: Along the axial direction of the puncture probe, the radius from both ends of the balloon to the center gradually increases.

5. The high and low temperature ablation needle according to claim 1, characterized in that: A reflective layer and / or a heat absorbing layer is arranged outside the air return pipe, wherein the reflective layer is used to reflect light and heat radiation, and the heat absorbing layer is used to absorb heat.

6. The high and low temperature ablation needle according to claim 1, characterized in that: The rewarming component includes a metal rod and a wire, and the wire is inserted into the liquid inlet pipe; The metal rod is arranged in the vacuum tube and contacts the puncture probe, and the wire is wound around the metal rod.

7. The high and low temperature ablation needle according to claim 1, characterized in that: The rewarming component is arranged in the vacuum tube and connected to the puncture probe; The rewarming assembly comprises: a head end electrode, a tail end electrode, a wire and a connecting ring; The connecting ring is arranged between the head end electrode and the tail end electrode to insulate and isolate the head end electrode and the tail end electrode; The wires are connected to the head end electrode and the tail end electrode respectively.

8. The high and low temperature ablation needle according to claim 6 or 7, characterized in that: The wire is provided with an insulating sheath.

9. The high and low temperature ablation needle according to claim 1, characterized in that: Also includes: handle, transfer vacuum tube and docking connector; The proximal end of the handle is connected to the vacuum tube, the distal end is connected to the transmission vacuum tube, and the liquid inlet tube is in communication with the transmission vacuum tube; The plug-in connector is arranged at the far end of the transmission vacuum tube and is used for connecting the ablative working medium.

10. An ablation device, characterized in that: A high and low temperature ablation needle comprising any one of claims 1-9.

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