Device for checking use specifications of pipettor

By setting up an inspection device between the pipette and the pipette tip, the thin-layer filter element and the color-changing reagent layer are used to detect liquid contamination, the pollution problem caused by irregular operation during use of the pipette is solved, and real-time monitoring and inspection of the standardized use of the pipette is achieved.

CN222599524UActive Publication Date: 2025-03-11HUBEI THREE GORGES POLYTECHNIC
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Patent Information

Application Number
CN202420655743.1
Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
Filing Date
2024-04-01
Publication Date
2025-03-11
Estimated Expiration
2034-04-01

AI Technical Summary

Technical Problem

Existing pipettes need to better control the spring retraction speed when absorbing liquid. If the speed is too fast or the pipette tip leaves the liquid level, it will lead to liquid contamination and affect the accuracy of the inspection data.

Method used

Design a device with standardized use of pipettes, including a housing of the inspection device, a thin-layer filter element and a color-changing reagent layer, which is arranged between the pipette and the pipette tip, absorbs possible liquid contamination through the thin-layer filter element, and judges the pollution situation through the color-changing reagent layer.

Benefits of technology

It effectively avoids contamination of the pipette, reduces maintenance costs, promptly detects irregular operation conditions, ensures the accuracy of inspection data, and improves inspection efficiency.

✦ Generated by Eureka AI based on patent content.

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Abstract

A device for checking use specifications of a pipettor is arranged between the pipettor and a pipettor gun head and comprises a checking device shell, the upper end of the checking device shell is sleeved outside the lower end of the pipettor, and the lower end of the checking device shell is sleeved inside the upper end of the pipettor gun head. A color-changeable reagent layer and a thin filter element are sequentially arranged in the lower end of the inspection device shell from top to bottom, the inspection device shell is in an inverted cone frustum shape, the large end and the small end of the inspection device shell are matched with the outer circle of the lower end of the pipettor and an inner hole in the upper end of a pipettor gun head respectively, and the large end is detachably sleeved on the outer circle of the lower end of the pipettor in a sealed mode. The small end is detachably inserted into an inner hole in the upper end of the pipettor gun head in a sealing manner; the device is used for detecting whether the pipettor is polluted due to high retraction speed of the spring in the using process of the pipettor, and does not cause adverse effects on the liquid taking process of the pipettor; and whether misoperation exists in the using process or not can be judged by observing whether the color-changeable reagent layer changes color or not, so that the aim of checking whether the pipettor used by an operator is standard or not is fulfilled.
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Description

Technical Field

[0001] The utility model relates to the technical field of inspection, in particular to a device for inspecting the use specification of a pipette. Background Art

[0002] The working principle of the pipette is that the piston achieves liquid suction and discharge through the expansion and contraction movement of the spring. Under the push of the piston, part of the air is discharged, the liquid is sucked in by the atmospheric pressure, and then the piston pushes the air to discharge the liquid. Therefore, when using the pipette, the speed and force of the pipette can be well controlled by operating it in conjunction with the expansion and contraction characteristics of the spring. The widely used pipette at present is the air displacement pipette, which is to press the piston down to press out the air inside the lower end of the pipette. After that, when the piston moves up, the air pressure inside the lower end of the pipette is less than the external air pressure, so that the liquid can be sucked up under the action of the external air pressure. In short, the air goes out and the liquid comes in. Its disadvantages are: When sucking liquid, it is necessary to better control the spring retraction speed. If the amount of liquid sucked is large and the spring retraction speed is too fast or the pipette tip has left the liquid surface when the spring retracts, the large negative pressure will directly suck the liquid into the pipette, causing contamination, which will affect the accuracy of the test data.

[0003] Therefore, a technology for inspecting or preventing the contamination of the liquid inside the pipette is needed at present. For example, CN218459554U discloses an anti-contamination needle-type pipette gun tip, including a gun tip body, a filter element and a syringe needle; the gun tip body is an integrally formed structure, including an interface section, a liquid suction section and a needle seat, and the interface section is a cylindrical structure; the filter element is engaged or embedded in the middle section or the lower middle end of the interface section, and the syringe needle is fixed in the needle seat. The utility model combines the functions of a filter element gun tip for a pipette and a syringe needle, and is specially matched with a manual pipette and an automatic pipetting workstation for puncture micro-pipetting without opening the cover, so as to avoid cross-contamination of samples and contamination of inspectors; however, the device is essentially a pipette gun tip, which is a commonly used consumable in the laboratory. The cost is relatively high when it is put into use, and the filter element in the gun tip can prevent the contamination of the pipette gun, but it cannot detect whether contamination has already occurred during use. Summary of the invention

[0004] The technical problem to be solved by the utility model is to provide a device for checking the use specification of a pipette, to check whether the pipette is contaminated due to the fast retraction speed of the spring during the use of the pipette, and not to cause adverse effects on the liquid collection process of the pipette; and whether improper operation has occurred during the use process can be determined by observing whether the color-changing reagent layer changes color, thereby achieving the purpose of checking whether the operator uses the pipette in a standardized manner.

[0005] In order to solve the above technical problems, the technical solution adopted by the utility model is: a device for testing the usage specifications of a pipette, which is arranged between the pipette and the pipette tip, and includes a testing device shell, the upper end of the testing device shell is sleeved on the outside of the lower end of the pipette, and the lower end of the testing device shell is sleeved on the inside of the upper end of the pipette tip, and the inside of the lower end of the testing device shell is sequentially sleeved with a color-changing reagent layer and a thin layer filter element from top to bottom.

[0006] In a preferred solution, the testing device housing is in the shape of an inverted frustum of a cone, and the sizes of the large and small ends of the testing device housing respectively match the outer circle of the lower end of the pipette and the inner hole size of the upper end of the pipette tip.

[0007] In a preferred solution, the inverted frustum-shaped large end of the testing device housing is sleeved on the outer circle of the lower end of the pipette, and the two are detachably sealed and fixed together.

[0008] In a preferred solution, the small end of the testing device housing is inserted into the inner hole at the upper end of the pipette tip, and the two are detachably sealed and connected and fixed together.

[0009] In a preferred embodiment, holes are provided in the centers of the thin layer filter element and the color-changeable reagent layer.

[0010] In a preferred embodiment, the color-changing reagent layer is stacked tightly on the thin-layer filter element, and the hole at the center of the thin-layer filter element is concentric with the hole at the center of the color-changing reagent layer and has the same diameter.

[0011] In a preferred embodiment, the outer circumference of the thin layer filter element and the color-changeable reagent layer is fixed to the inner wall of the testing device housing by adhesive.

[0012] In a preferred embodiment, the cross-sectional diameter of the thin-layer filter element and the color-changeable reagent layer is 3 / 4 to 4 / 5 of the outer diameter of the housing of the installation position inspection device.

[0013] In a preferred embodiment, the thin layer filter element is absorbent cotton or absorbent sponge.

[0014] In a preferred embodiment, the color-changing reagent layer is a water-changing color label paper made of a hydrogel material.

[0015] The utility model provides a small area concrete curing device, which has the following beneficial effects:

[0016] 1. The utility model is provided with a thin layer filter element, which is a strong water-absorbing material, which can effectively prevent the liquid from impacting upward when using the pipette, thereby protecting the pipette from contamination and reducing the maintenance cost of the pipette;

[0017] 2. The utility model is provided with a color-changing reagent layer, which changes color sensitively when encountering water, and can promptly discover the fact that the operator is not operating in a standardized manner;

[0018] 3. The housing of the calibration device of the utility model is set as an inverted frustum structure, so that the size range of the applicable pipettes and pipette tips is wider and the practicality is stronger;

[0019] 4. The structural size design of the calibration device housing, thin-layer filter element and color-changing reagent layer of the utility model effectively ensures the effective sealing between the calibration device housing and the pipette and the pipette tip, and is more conducive to the operator to promptly detect the contamination of the liquid at the pipette tip;

[0020] 5. The connection structure design of the housing of the calibration device of the utility model and the pipette and the pipette tip makes the connection between them tight while not affecting the use of the original pipette, and no special consumables are required. If the device does not change color, it means that it is not contaminated and can be reused;

[0021] 6. The thin filter element and the color-changing reagent layer of the device are provided with holes in the center, so that the pressure in the original pipette is not affected during use, and the normal use of the pipette is not affected;

[0022] 7. The utility model is assembled between a common pipette tip and a pipette gun when in use, and the inspection room does not need to update new pipette tip consumables;

[0023] 8. The color-changing reagent layer inside the utility model changes color quickly when it comes into contact with water, which quickly helps the operator determine whether there has been improper operation during use, so as to discover problems in time, thereby ensuring the accuracy of the test data and avoiding repeated testing work, thereby improving the test efficiency. BRIEF DESCRIPTION OF THE DRAWINGS

[0024] The utility model is further described below in conjunction with the accompanying drawings and implementation examples:

[0025] Figure 1 It is a schematic diagram of the overall structure of the utility model;

[0026] Figure 2 It is a cross-sectional view of the overall structure of the utility model;

[0027] Figure 3 This is a schematic diagram of the assembly of the housing, thin-layer filter element and color-changing reagent layer of the testing device of the utility model;

[0028] In the figure: a pipette 1, a testing device housing 2, a pipette tip 3, a thin layer filter element 4, and a color-changeable reagent layer 5. DETAILED DESCRIPTION

[0029] like Figures 1 to 3As shown, a device for testing the standard of use of a pipette is arranged between a pipette 1 and a pipette tip 3, and comprises a testing device housing 2, wherein the upper end of the testing device housing 2 is sleeved on the outside of the lower end of the pipette 1, and the lower end of the testing device housing 2 is sleeved on the inside of the upper end of the pipette tip 3, and the inside of the lower end of the testing device housing 2 is sequentially sleeved with a color-changing reagent layer 5 and a thin layer filter element 4 from top to bottom.

[0030] In this embodiment, the testing device housing 2 is in the shape of an inverted frustum of a cone, and the sizes of the large and small ends of the testing device housing 2 match the outer circle of the lower end of the pipette 1 and the inner hole size of the upper end of the pipette tip 3 respectively.

[0031] Furthermore, the inverted frustum-shaped large end of the testing device housing 2 is sleeved on the outer circle of the lower end of the pipette 1, and the two are detachably sealed and fixed together.

[0032] Furthermore, the small end of the testing device housing 2 is inserted into the inner hole at the upper end of the pipette tip 3, and the two are detachably sealed and fixed together.

[0033] Furthermore, holes are provided at the centers of the thin layer filter element 4 and the color-changeable reagent layer 5 .

[0034] Furthermore, the color-changing reagent layer 5 is stacked and closely attached to the thin-layer filter element 4 , and the hole at the center of the thin-layer filter element 4 and the hole at the center of the color-changing reagent layer 5 are concentric and of equal diameter.

[0035] Furthermore, the outer circumference of the thin layer filter element 4 and the color-changeable reagent layer 5 are bonded and fixed to the inner wall of the testing device housing 2 by an adhesive.

[0036] Furthermore, the cross-sectional diameters of the thin-layer filter element 4 and the color-changeable reagent layer 5 are 3 / 4 to 4 / 5 of the outer diameter of the housing 2 of the installation position inspection device.

[0037] Furthermore, the thin layer filter element 4 is absorbent cotton or absorbent sponge.

[0038] Furthermore, the color-changing reagent layer 5 is a water-changing color label paper, which is made of a hydrogel material.

[0039] When used specifically: This example is a device for checking whether the use of a pipette is standardized. When the user does not operate in a standardized manner, the liquid in the pipette tip 3 will be sucked upward to the lower end of the pipette by the negative pressure formed by the pipette, which will cause contamination of the pipette. When using this device, the device is installed between the lower end of the pipette 1 and the upper end of the pipette tip 3. The size of the upper end of the device housing 2 is consistent with the size of the upper end of the pipette tip 3 that the pipette is adapted to, and the size of the lower end of the device housing 3 is consistent with the size of the lower end of the pipette. Therefore, after installing the device, the compatibility of the pipette and the pipette tip is not affected, and the pipette can be used normally. There are a color-changing reagent layer 5 and a thin filter layer 4 inside the device. The filter layer 4 can quickly absorb the liquid that is about to contaminate the pipette 1 during the pipetting process of the pipette 1 and transfer the liquid to the color-changing reagent layer 5. The latter will change color after contacting the liquid, indicating that the operator is not using the pipette 1 in a standardized manner at this time, causing the liquid in the pipette tip 3 to contaminate the pipette 1 upward. Since the color-changing reagent layer 5 and the thin filter element layer 4 have a central hole at the center, the negative pressure generated during the liquid aspiration process is not affected, and the liquid aspiration resistance is not increased, so the pipette 1 can be used normally.

[0040] In the preferred embodiment, the testing device shell 2 is in the shape of an inverted frustum, and the sizes of the large and small ends of the testing device shell 2 are respectively matched with the outer circle of the lower end of the pipette 1 and the inner hole size of the upper end of the pipette tip 3; the above structural arrangement makes the testing device shell 2 applicable to a wider range of sizes of pipettes 1 and pipette tips 3, with higher interchangeability and stronger practicality.

[0041] In the preferred scheme, the inverted frustum-shaped large end of the testing device shell 2 is sleeved on the outer circle of the lower end of the pipette 1, and the two are detachably sealed and installed to be fixed together; the small end of the testing device shell 2 is inserted into the inner hole of the upper end of the pipette tip 3, and the two are detachably sealed and installed to be fixed together; the above arrangement effectively ensures timely and reliable identification of liquid contamination in the testing device shell 2, while ensuring the cleanliness of the testing liquid in the device, thereby further ensuring the accuracy of the test results.

[0042] In a preferred embodiment, holes are provided in the centers of the thin layer filter element 4 and the color-changing reagent layer 5; the color-changing reagent layer 5 is stacked and tightly attached to the thin layer filter element 4, and the hole in the center of the thin layer filter element 4 is concentric with and equal in diameter to the hole in the center of the color-changing reagent layer 5; the above arrangement ensures that the pressure of the pipette 1 does not change and does not affect the use of the pipette 1, while the contaminated liquid can be promptly adsorbed onto the thin layer filter element 4, thereby improving the inspection efficiency and the accuracy and timeliness of the inspection results.

[0043] In a preferred embodiment, the outer circumference of the thin layer filter element 4 and the color-changing reagent layer 5 are bonded and fixed to the inner wall of the testing device housing 2 by an adhesive; the above arrangement enables the thin layer filter element 4 and the color-changing reagent layer 5 to be effectively fixed, thereby ensuring the effective implementation of the test.

[0044] In the preferred scheme, the cross-sectional diameter of the thin layer filter element 4 and the color-changing reagent layer 5 is 3 / 4 to 4 / 5 of the outer diameter of the testing device housing 2 at the installation position; the above arrangement not only ensures the strength of the testing device housing 2, but also enables the smooth implementation of the threaded sealing between the testing device housing 2 and the pipette 1 and the pipette tip 3, and also facilitates disassembly, which is conducive to timely and intuitive observation of the color change of the color-changing reagent layer 5, thereby timely discovering the contamination of the liquid at the pipette tip 3.

[0045] In the preferred embodiment, the thin layer filter element 4 is absorbent cotton or absorbent sponge; the above arrangement effectively ensures that the contaminated liquid at the pipette tip 3 is absorbed in time, and can be transmitted to the color-changing reagent layer 5 in time, while preventing it from further rising and contaminating the liquid in the pipette 1, thereby further ensuring the accuracy of the test results and avoiding repeated inspection work.

[0046] In a preferred embodiment, the color-changing reagent layer 5 is a water-changing color label paper made of a hydrogel material; the above arrangement enables the color change of the color-changing reagent layer 5 to be achieved while promptly detecting the contamination of the pipette tip 3, thereby further ensuring the effectiveness and accuracy of the test results. At the same time, the water-changing color label paper made of a hydrogel material can be reused after drying, which is energy-saving and environmentally friendly.

[0047] In summary, the utility model patent proposes a device for checking the standard use of a pipette, which is composed of a verification device housing 2, a thin layer filter element 4 and a color-changing reagent layer 5. When in use, the device is installed between the pipette 1 and the pipette tip 3 to form an independent space. When the operator uses the pipette tip 3 improperly, causing the water in the tip to impact upward, it will pass through the thin layer filter element 4 and the color-changing reagent layer 5 of the device, wherein the thin layer filter element 4 is a strong water-absorbing material that can transfer water to the color-changing reagent layer 5 and the water will no longer enter the pipette 1 upward. The color-changing reagent layer 5 will change color after absorbing water, thereby protecting the pipette 1 from contamination and detecting the operator's operating problems; there is no adhesive effect between the thin layer filter element 4 and the color-changing reagent layer 5, and the water absorbed in the thin layer filter element 4 can be directly transferred to the color-changing reagent layer 5, thereby detecting that water is absorbed; the verification device housing 2 of the device is set to an inverted frustum structure, so that the size range of the pipette 1 and the pipette tip 3 that it is applicable to is The utility model is wider and more practical; the housing 2 of the device for verifying the device is tightly connected with the pipette 1 and the pipette tip 3, so as to further ensure the accuracy and timeliness of the test results; the thin-layer filter element 4 and the color-changing reagent layer 5 of the device are provided with holes in the center, so as not to affect the pressure in the original pipette 1 during use, and not to affect the normal use of the pipette 1; the device is exquisitely designed and simple to operate, and can solve the problem that the operator is operating the pipette 1 to take liquid due to improper operation, which leads to the contamination of the pipette 1, avoids various inaccurate test results caused by the continued use of the contaminated pipette 1, and reduces the damage and aging of the pipette 1; at the same time, the fact that the operation is not standardized can be discovered, which can help beginners to standardize the operation practice, and the device is easy to install and disassemble, and can be reused when the color of the device is not found to be changed; different sizes can be set during production to match different models of pipettes 1 and pipette tips 3, which has high practical application value, good economic benefits and social benefits.

Claims

1. A device for checking the use specification of a pipette, characterized in that: The device is arranged between a pipette (1) and a pipette tip (3), and comprises a testing device housing (2), wherein the upper end of the testing device housing (2) is sleeved on the outside of the lower end of the pipette (1), and the lower end of the testing device housing (2) is sleeved on the inside of the upper end of the pipette tip (3), and the inside of the lower end of the testing device housing (2) is sleeved with a color-changeable reagent layer (5) and a thin-layer filter element (4) in sequence from top to bottom.

2. A device for checking the use specification of a pipette according to claim 1, characterized in that: The testing device housing (2) is in the shape of an inverted frustum of a cone, and the sizes of the large and small ends of the testing device housing (2) respectively match the outer circle of the lower end of the pipette (1) and the inner hole size of the upper end of the pipette tip (3).

3. A device for checking the use specification of a pipette according to claim 2, characterized in that: The inverted frustum-shaped large end of the testing device housing (2) is sleeved on the outer circle of the lower end of the pipette (1), and the two are detachably sealed and connected and fixed together.

4. A device for checking the use specification of a pipette according to claim 3, characterized in that: The small end of the testing device housing (2) is inserted into the inner hole at the upper end of the pipette tip (3), and the two are detachably sealed and fixedly connected together.

5. A device for checking the use specification of a pipette according to claim 1, characterized in that: The thin layer filter element (4) and the color-changeable reagent layer (5) are both provided with holes at their centers.

6. A device for checking the use specification of a pipette according to claim 5, characterized in that: The color-changing reagent layer (5) is stacked and closely attached to the thin-layer filter element (4), and the hole at the center of the thin-layer filter element (4) and the hole at the center of the color-changing reagent layer (5) are concentric and of equal diameter.

7. A device for checking the use specification of a pipette according to claim 1, characterized in that: The outer circumference of the thin layer filter element (4) and the color-changeable reagent layer (5) are bonded and fixed to the inner wall of the testing device housing (2) by an adhesive.

8. A device for checking the use specification of a pipette according to claim 1, characterized in that: The cross-sectional diameters of the thin-layer filter element (4) and the color-changeable reagent layer (5) are 3 / 4 to 4 / 5 of the outer diameter of the housing (2) of the installation position inspection device.

9. A device for checking the use specification of a pipette according to claim 1, characterized in that: The thin layer filter element (4) is water-absorbing cotton or water-absorbing sponge.

10. A device for checking the use specification of a pipette according to claim 1, characterized in that: The color-changing reagent layer (5) is a water-changing color label paper, which is made of a hydrogel material.

Citation Information

Patent Citations

  • Anti-pollution needle type pipette tip

    CN218459554U