A quantitative kit for detecting hepatitis B virus nucleic acid

By designing a protective mechanism and a constant temperature mechanism in the hepatitis B virus nucleic acid detection kit, the existing kits have poor protection effect and cumbersome insulation structure, and efficient protection of the reagent tube and precise control of the internal temperature of the storage box are achieved.

CN222714045UActive Publication Date: 2025-04-04杭州泰熙生物技术有限公司
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Patent Information

Application Number
CN202421320593.5
Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
Filing Date
2024-06-12
Publication Date
2025-04-04
Estimated Expiration
2034-06-12

AI Technical Summary

Technical Problem

The existing hepatitis B virus nucleic acid detection kit has poor protective effect, a single structure and a disposable consumable, and cannot effectively protect the reagent tube, and the insulation structure is cumbersome and cannot be used to control the constant temperature.

Method used

A quantitative kit for nucleic acid detection of hepatitis B virus including a protective mechanism and a constant temperature mechanism was designed. The protective mechanism improves the stability and protective effect of the reagent tube by flipping the shaft and the protective cover plate, combining the screw-tight assembly and the sponge plate. The constant temperature mechanism realizes constant temperature control of the internal temperature of the storage box through a temperature control machine and a temperature control pipe.

Benefits of technology

It effectively improves the protection and storage effect of the reagent tube, prevents fragmentation caused by shaking and collision of the reagent tube, and realizes accurate control of the internal temperature of the storage box, meeting the low-temperature storage needs of virus samples.

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Abstract

The utility model belongs to the technical field of virus detection reagent tube storage equipment, and provides a quantitative reagent kit for hepatitis B virus nucleic acid detection, including a storage box for centrally storing virus reagent tubes, a protection mechanism for improving the protection effect of the device and preventing the reagent tubes from shaking and causing breakage is arranged above the storage box, and a constant temperature mechanism for improving the preservation effect of the reagent tubes is arranged on the outside of the storage box; the utility model can greatly improve the protection safety provided by the virus reagent tubes when they are placed inside the storage box to a certain extent through the protection mechanism, the flip shaft and protection cover plate provided in the protection mechanism not only facilitate the staff to take and put the reagent tubes, but the compression and cooperation of the sliding screw, the clamping plate and the rotator provided in the screw tightening assembly can effectively improve the safety and stability of the reagent tubes placed in the storage box, prevent the reagent tubes from shaking and colliding and causing breakage, and the sponge plate can also prevent damage to the reagent tubes on the basis of improving the compression effect.
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Description

Technical Field

[0001] The utility model belongs to the technical field of virus detection reagent tube storage equipment, in particular to a quantitative reagent kit for hepatitis B virus nucleic acid detection. Background Art

[0002] Hepatitis B virus (HBV) is a hepatotropic virus that mainly exists in liver cells and damages liver cells, causing inflammation, necrosis and fibrosis of liver cells. It is the main cause of human viral hepatitis. HBV infection is prevalent worldwide, but the prevalence of HBV infection varies greatly in different regions. Therefore, the prevention and diagnosis and treatment of HBV is the top priority of national infectious disease control.

[0003] After searching, a Chinese patent with publication number CN215555826U mentioned a hepatitis B virus nucleic acid detection kit, including a kit body, the back of the kit body is rotatably connected to a box cover by a hinge, an ice box is provided at the bottom of the inner cavity of the kit body, and a plurality of cap slots are provided on one side of the box cover. An ice box is provided inside the kit body, water and a sponge are placed in the ice box, and then the ice box is placed in a refrigerator, waiting for the water to freeze in the sponge, and then the ice box is placed inside the kit body. When the reagent tube is inserted into the corresponding tube groove, the insulation hole and the through hole, the cold air in the ice box is dissipated to the surface of the reagent tube through the through hole, and the insulation cotton can prevent the cold air from dissipating to a certain extent. Through this structure, the kit can be kept in a low temperature state for a long time, thereby improving the detection accuracy.

[0004] However, the main function of the test kit is to store the completed virus reagent tubes, and most of the existing test kits have a single structure and are disposable consumables. A slot plate (for placing the reagent tubes) is provided inside the box body, and the box body is mostly made of paper material. Although the production cost is low and easy to use, the protection effect is poor. The reagent tubes are prone to shaking and colliding when placed in the box, causing breakage. The test kit structure is not perfect enough and cannot protect the virus reagent tubes well. In addition, the insulation structure provided above is cumbersome to use and cannot be controlled at a constant temperature.

[0005] To this end, those skilled in the art have proposed a quantitative kit for detecting hepatitis B virus nucleic acid to solve the problems raised by the background technology. Utility Model Content

[0006] In order to solve the above technical problems, the utility model provides a quantitative kit for detecting hepatitis B virus nucleic acid, so as to solve the problems of poor protection effect and defects in device structure in the prior art.

[0007] A quantitative reagent kit for detecting hepatitis B virus nucleic acid comprises a storage box for centrally storing virus reagent tubes, a protective mechanism for improving the protective effect of the device and preventing the reagent tubes from shaking and breaking is arranged above the storage box, and a constant temperature mechanism for improving the preservation effect of the reagent tubes is arranged outside the storage box.

[0008] Preferably, the protection mechanism includes a flip shaft and a protection cover plate, the flip shaft is arranged at the outer end of the opening of the storage box, the protection cover plate is closed and connected to the outer side of the flip shaft, and a lock is provided on one side of the storage box for cooperating with the protection cover plate to improve the tightness of the cover.

[0009] Preferably, the inner side of the protective cover plate is provided with a screw-tightening assembly for pressing the reagent tube to prevent shaking when the cover is closed, and the screw-tightening assembly includes a sliding screw and a pressing plate, and the pressing plate is welded to the bottom end of the sliding screw.

[0010] Preferably, a rotator for rotating and tightening the screw is provided on the outside of the sliding screw and is arranged above the protective cover plate. A sponge plate is fixed under the clamping plate to prevent the clamping work from damaging the reagent tube and to improve the anti-shake effect. A pull ring is also provided above the protective cover plate for easy closure.

[0011] Preferably, the constant temperature mechanism includes a temperature controller and a temperature control tube with one end passing through the inside of the storage box, the other end of the temperature control tube is connected to the bottom of the temperature controller, and a control panel for displaying the temperature inside the box and adjusting the temperature control value is provided on the outside of the temperature controller.

[0012] Preferably, one side of the temperature controller is connected to a liquid nitrogen tank used for refrigeration work and capable of placing refrigeration equipment and fixed to the outside of the storage box.

[0013] Compared with the prior art, the utility model has the following beneficial effects:

[0014] 1. The utility model can greatly improve the protection safety provided by the virus reagent tube when it is placed inside the storage box to a certain extent through the protective mechanism. The flip shaft and protective cover plate provided in the protective mechanism not only facilitate the staff to take and place the reagent tube, but also enhance the protection. The sliding screw, clamping plate and rotator provided in the screw tightening assembly work together to effectively improve the safety and stability of the reagent tube placed in the storage box and prevent the reagent tube from shaking and colliding and causing breakage. At the same time, the sponge plate can also prevent damage to the reagent tube on the basis of improving the clamping effect.

[0015] 2. The utility model further improves the protective performance of the device through the constant temperature mechanism. Due to the influence of the virus reagent tube, the internal environment of the storage box is generally in a low temperature environment to meet the subsequent detection of virus samples. The temperature control machine and temperature control tube in the constant temperature mechanism can not only adjust the temperature control value, but also display the temperature inside the box for easy observation, so as to better control the internal temperature environment of the storage box. BRIEF DESCRIPTION OF THE DRAWINGS

[0016] Figure 1 It is a schematic diagram of the overall first-view structure of the utility model;

[0017] Figure 2 It is a schematic diagram of the overall structure of the utility model from a second viewing angle;

[0018] Figure 3 This is a schematic diagram of the protection mechanism structure of the utility model;

[0019] Figure 4 It is a schematic diagram of the structure of the constant temperature mechanism of the utility model.

[0020] In the figure:

[0021] 1. Storage box; 2. Protection mechanism; 3. Constant temperature mechanism; 4. Flip shaft; 5. Protection cover; 6. Lock; 7. Sliding screw; 8. Pressing plate; 9. Rotator; 10. Sponge plate; 11. Pull ring; 12. Temperature controller; 13. Temperature control tube; 14. Control panel; 15. Liquid nitrogen tank. DETAILED DESCRIPTION

[0022] The following is a further detailed description of the implementation of the present invention in conjunction with the accompanying drawings and examples. The following examples are used to illustrate the present invention, but cannot be used to limit the scope of the present invention.

[0023] As attached Figure 1 To Attachment Figure 4 As shown:

[0024] Embodiment 1: The utility model provides a quantitative reagent kit for detecting hepatitis B virus nucleic acid, comprising a storage box 1 for collectively storing virus reagent tubes, a protective mechanism 2 for improving the protective effect of the device and preventing the reagent tubes from shaking and causing breakage is provided above the storage box 1, and a constant temperature mechanism 3 for improving the preservation effect of the reagent tubes is provided on the outside of the storage box 1.

[0025] The protective mechanism 2 can, to a certain extent, greatly improve the protective safety provided when the virus reagent tube is placed inside the storage box 1. The flip shaft 4 and the protective cover plate 5 provided in the protective mechanism 2 not only facilitate the staff's work of taking and placing the reagent tube, but also enhance the protective performance. The sliding screw 7, the clamping plate 8, and the rotator 9 provided in the screw tightening assembly can effectively improve the safety and stability of the reagent tube placed in the storage box 1, and prevent the reagent tube from shaking and colliding and causing breakage. At the same time, the sponge plate 10 can also prevent damage to the reagent tube on the basis of improving the clamping effect.

[0026] The constant temperature mechanism 3 further improves the protective performance of the device. Due to the influence of the virus reagent tube, the internal environment of the storage box 1 is generally in a low temperature environment to meet the subsequent detection of virus samples. The temperature control machine 12 and temperature control tube 13 provided in the constant temperature mechanism 3 can not only adjust the temperature control value, but also display the temperature inside the box for easy observation, so as to better control the internal temperature environment of the storage box 1.

[0027] The protection mechanism 2 includes a flip shaft 4 and a protection cover 5. The flip shaft 4 is arranged at the outer end of the opening of the storage box 1. The protection cover 5 is closed and connected to the outer side of the flip shaft 4. A lock 6 is provided on one side of the storage box 1 for cooperating with the protection cover 5 to improve the tightness of the cover.

[0028] As can be seen from the above, the flip shaft 4 and the protective cover 5 mainly provide a closing effect for the storage box 1 to enhance the protection safety. The flip shaft 4 is arranged at the outer end of the opening of the storage box 1, and the protective cover 5 is closed and connected to the outside of the flip shaft 4. When closing, the protective cover 5 is flipped along the outside of the flip shaft 4 to achieve the closing effect. The main function of the lock 6 is to prevent the protective cover 5 from opening when it is not firmly closed. When closing, the buckle of the protective cover 5 can be inserted into the lock 6 to limit it (pressing the lock 6 can pop out the buckle of the protective cover 5 for easy opening) to enhance the tightness of the cover.

[0029] The inner side of the protective cover plate 5 is provided with a screw-tightening assembly for pressing the reagent tube to prevent shaking when the cover is closed. The screw-tightening assembly includes a sliding screw rod 7 and a pressing plate 8. The pressing plate 8 is welded to the bottom end of the sliding screw rod 7.

[0030] A rotator 9 for rotating and tightening the screw is provided on the outside of the sliding screw 7 and is arranged above the protective cover 5. A sponge plate 10 is fixed under the clamping plate 8 to prevent the clamping work from damaging the reagent tube and to improve the anti-shaking effect. A pull ring 11 is also provided above the protective cover 5 for easy closure.

[0031] The main working effect of the screw tightening assembly is to prevent the reagent tube from being placed in the storage box 1 and from shaking, colliding and breaking during the transportation of the storage box 1. Since the sponge plate 10 is fixed under the clamping plate 8, the clamping plate 8 is welded to the lower end of the sliding screw 7, and a rotator 9 for rotating and tightening is provided on the outside of the sliding screw 7 and is arranged above the protective cover plate 5. When the rotator 9 rotates, the sliding screw 7 is pressed downward along the inner side of the rotator 9 toward the inside of the storage box 1, and the sponge plate 10 fixed under the clamping plate 8 is attached to the top of the reagent tube to achieve a clamping effect on it. Since the reagent tube is subjected to the clamping and fitting effect of the sponge plate 10, the reagent tube in the box is effectively prevented from shaking, colliding and breaking during the transportation of the storage box 1.

[0032] Embodiment 2: The constant temperature mechanism 3 includes a temperature controller 12 and a temperature control tube 13 with one end passing through the inner side of the storage box 1, and the other end of the temperature control tube 13 is connected to the bottom of the temperature controller 12. A control panel 14 for displaying the temperature inside the box and adjusting the temperature control value is provided on the outer side of the temperature controller 12.

[0033] One side of the temperature control machine 12 is connected to a liquid nitrogen tank 15 for refrigeration work and capable of placing refrigeration equipment and fixed to the outside of the storage box 1 .

[0034] As can be seen from the above, after a small liquid nitrogen cold air tank is placed in the liquid nitrogen tank 15 (it can also be replaced by other refrigeration equipment), the interface of the liquid nitrogen cold air tank is connected to the adapter interface of the liquid nitrogen tank 15, and the liquid nitrogen tank 15 is connected to one side of the temperature controller 12. A control panel 14 for displaying the temperature in the box and adjusting the temperature control value is provided on the outside of the temperature controller 12. The working value of the temperature controller 12 is adjusted by the control button of the control panel 14. The temperature control tube 13 connected below the temperature controller 12 releases cold air to the inside of the storage box 1 to achieve low-temperature pretreatment, and the staff can intervene and adjust according to the temperature control value displayed on the control panel 14, so as to better control the constant temperature environment inside the storage box 1.

[0035] In the drawings of the embodiments disclosed in the present utility model, only the structures related to the embodiments disclosed in the present utility model are involved, and other structures can refer to the general design. In the absence of conflict, the same embodiment and different embodiments of the present utility model can be combined with each other.

[0036] The embodiments of the present invention are provided for the purpose of illustration and description. Although the embodiments of the present invention have been shown and described above, it can be understood that the above embodiments are exemplary and cannot be understood as limitations on the present invention. Ordinary technicians in this field can change, modify, replace and modify the above embodiments within the scope of the present invention.

Claims

1. A quantitative kit for detecting hepatitis B virus nucleic acid, characterized in that: The invention comprises a storage box (1) for centrally storing virus reagent tubes, wherein a protective mechanism (2) for improving the protective effect of the device and preventing the reagent tubes from shaking and causing breakage is provided above the storage box (1), and a constant temperature mechanism (3) for improving the preservation effect of the reagent tubes is provided outside the storage box (1).

2. A quantitative kit for detecting hepatitis B virus nucleic acid as claimed in claim 1, characterized in that: The protection mechanism (2) comprises a flip shaft (4) and a protection cover plate (5); the flip shaft (4) is arranged at the outer end of the opening of the storage box (1); the protection cover plate (5) is closed and connected to the outer side of the flip shaft (4); and a lock buckle (6) is provided on one side of the storage box (1) for cooperating with the protection cover plate (5) to improve the tightness of the cover.

3. A quantitative kit for detecting hepatitis B virus nucleic acid as claimed in claim 2, characterized in that: The inner side of the protective cover plate (5) is provided with a screw-tightening assembly for pressing the reagent tube to prevent shaking when the cover is closed. The screw-tightening assembly includes a sliding screw (7) and a pressing plate (8). The pressing plate (8) is welded to the bottom end of the sliding screw (7).

4. A quantitative kit for detecting hepatitis B virus nucleic acid as claimed in claim 3, characterized in that: The outer side of the sliding screw (7) is provided with a rotator (9) for rotating and tightening the screw and is arranged above the protective cover (5). A sponge plate (10) is fixed below the clamping plate (8) to prevent the clamping work from damaging the reagent tube and to improve the anti-shaking effect. A pull ring (11) for convenient closing is also provided above the protective cover (5).

5. A quantitative kit for detecting hepatitis B virus nucleic acid as claimed in claim 1, characterized in that: The constant temperature mechanism (3) comprises a temperature controller (12) and a temperature control tube (13) with one end penetrating the inner side of the storage box (1), the other end of the temperature control tube (13) being connected to the bottom of the temperature controller (12), and a control panel (14) for displaying the temperature inside the box and adjusting the temperature control value is provided on the outer side of the temperature controller (12).

6. A quantitative kit for detecting hepatitis B virus nucleic acid as claimed in claim 5, characterized in that: One side of the temperature control machine (12) is connected to a liquid nitrogen tank (15) used for refrigeration work and capable of placing refrigeration equipment and fixed to the outside of the storage box (1).

Citation Information

Patent Citations

  • Hepatitis B virus nucleic acid detection kit

    CN215555826U