Biological sample freezing device
By designing the pick-up and placement device in the biological sample freezing device and simplifying the layout of the frozen storage shelf, the complex problem of the freezing box storage process in the prior art is solved, and higher automation and reliability in low-temperature environments are achieved.
Patent Information
- Application Number
- CN202421339447.7
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- Filing Date
- 2024-06-12
- Publication Date
- 2025-04-08
- Estimated Expiration
- 2034-06-12
AI Technical Summary
The existing biological sample freezing device is not very automated, which leads to the complicated storage process of the frozen storage box and is prone to failure in low-temperature environments.
A biological sample freezing device is designed, and the freezing box is accessed using the pick-up and placement device. In the design of the frozen storage shelf, it is ensured that each placement cavity is only used to place one freezing box, and the placement cavity is not arranged in the horizontal direction, thereby simplifying the pick-up and placement process.
By simplifying the pick-up and placement process of the frozen storage shelf, the structural complexity is reduced, and the risk of failure in low-temperature environments is avoided, making the biological sample frozen storage device more automated and reliable.
Smart Images
Figure CN222722323U_ABST
Abstract
Description
Technical Field
[0001] The present application relates to the technical field of biological sample cryopreservation, and in particular to a biological sample cryopreservation device. Background Art
[0002] With the rapid development of the biopharmaceutical industry, large-scale biological sample banks have emerged, and the storage volume of biological samples has become larger and larger. Generally, biological samples such as tissues and cells in clinical or laboratory settings are placed in biological sample freezing devices for storage. However, the degree of automation of biological sample freezing devices in related technologies is not high. Utility Model Content
[0003] In view of the above problems, the present application is proposed to provide a biological sample freezing device that overcomes the above problems or at least partially solves the above problems.
[0004] The present application provides a biological sample freezing device, comprising: a cavity, the cavity defining a receiving cavity; a first freezing rack, the first freezing rack being arranged in the receiving cavity, the first freezing rack defining a plurality of first placement cavities, the first placement cavity having an opening at at least one end in a first horizontal direction, the first placement cavity being only used to place one freezing box in the first horizontal direction, the freezing box being used to store biological samples, and any two of the first placement cavities being not arranged along the first horizontal direction; and a taking and placing device, the taking and placing device being arranged inside or outside the receiving cavity, the taking and placing device being used to take and place the freezing box through the opening.
[0005] Optionally, the first placement cavity has an opening at a first end in the horizontal first direction.
[0006] Optionally, the biological sample freezing device also includes: a second freezing rack, the second freezing rack is arranged in the accommodating chamber, the second freezing rack defines a plurality of second placement chambers, the second placement chamber has an opening at the second end in the horizontal first direction, the second placement chamber is only used to place one freezing box in the horizontal first direction, the freezing box is used to store biological samples, and any two of the second placement chambers are not arranged along the horizontal first direction.
[0007] Optionally, the first end of the second freezing rack in the horizontal first direction is fixedly connected, fitted or spaced from the second end of the first freezing rack in the horizontal first direction.
[0008] Optionally, the second placement cavity is closed at a first end in the horizontal first direction.
[0009] Optionally, a first end of the second placement cavity in the horizontal first direction is attached to or fixed to an inner wall of the accommodating cavity.
[0010] Optionally, the first placement cavity is closed at a second end in the horizontal first direction.
[0011] Optionally, a second end of the first placement cavity in the horizontal first direction is attached to or fixed to an inner wall of the accommodating cavity.
[0012] Optionally, the first freezing rack is movably disposed in the accommodating chamber, and / or the taking and placing device is movably disposed inside or outside the accommodating chamber.
[0013] Optionally, the cavity includes an inner liner defining the accommodating cavity and a shell arranged outside the inner liner, and a heat preservation device is arranged between the inner liner and the shell.
[0014] The biological sample freezing device provided in the present application utilizes a picking and placing device to store and retrieve freezing boxes, and the first placement cavity is only used to place one freezing box in the horizontal first direction, and any two first placement cavities are not arranged along the horizontal first direction, so that the process of taking and placing the freezing rack is simple, and the picking and placing mechanism is easy to operate, avoiding the risk of failure in a low-temperature environment due to a complex structure. BRIEF DESCRIPTION OF THE DRAWINGS
[0015] Other objects and advantages of the present application will be apparent from the following description of the present application with reference to the accompanying drawings, which will help to provide a comprehensive understanding of the present application.
[0016] Figure 1 is a schematic diagram of a cavity of a biological sample freezing device provided according to some embodiments of the present application;
[0017] Figure 2 is a cross-sectional view of a first freezing rack of a biological sample freezing device provided according to some embodiments of the present application;
[0018] Figure 3 is a cross-sectional view of a first freezing rack and a second freezing rack of a biological sample freezing device provided according to some embodiments of the present application;
[0019] Figure 4 is a cross-sectional view of a biological sample freezing device provided according to some embodiments of the present application.
[0020] Among them, 10 is a biological sample freezing device, 100 is a cavity, 110 is a receiving cavity, 200 is a first freezing rack, 210 is a first placement cavity, 220 is a freezing box, 300 is a taking and placing device, 400 is a second freezing rack, and 410 is a second placement cavity. DETAILED DESCRIPTION
[0021] In order to make the purpose, technical solution and advantages of the present application clearer, the technical solution of the present application will be clearly and completely described below in conjunction with the drawings of the embodiments of the present application. Obviously, the described embodiment is one embodiment of the present application, not all embodiments. Based on the described embodiments of the present application, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of this application.
[0022] Unless otherwise defined, technical or scientific terms used in this application should have the common meanings understood by persons having ordinary skills in the field to which this application belongs.
[0023] This embodiment provides a biological sample freezing device 10. Figure 1 is a schematic diagram of a cavity 100 of a biological sample freezing device 10 provided according to some embodiments of the present application; Figure 2 is a cross-sectional view of a first freezing rack 200 of a biological sample freezing device 10 provided according to some embodiments of the present application (arrows indicate the horizontal direction); Figure 3 is a cross-sectional view of a first freezing rack 200 and a second freezing rack 400 of a biological sample freezing apparatus 10 provided according to some embodiments of the present application (arrows indicate the horizontal direction); Figure 4 is a cross-sectional view of a biological sample freezing device 10 provided according to some embodiments of the present application.
[0024] The biological sample freezing device 10 includes a cavity 100, a first freezing rack 200, and a pick-and-place device 300. The cavity 100 defines a receiving cavity 110; the first freezing rack 200 is disposed in the receiving cavity 110, and the first freezing rack 200 defines a plurality of first placement cavities 210, wherein at least one end of the first placement cavity 210 in a horizontal first direction has an opening, and the first placement cavity 210 is only used to place one freezing box 220 in the horizontal first direction, and the freezing box 220 is used to store biological samples, and any two of the first placement cavities 210 are not arranged along the horizontal first direction; the pick-and-place device 300 is disposed inside or outside the receiving cavity 110, and the pick-and-place device 300 is used to take and place the freezing box 220 through the opening.
[0025] The biological sample freezing device 10 provided in this embodiment utilizes a pick-and-place device 300 to store and retrieve a freezing box 220, and the first placement cavity 210 is only used to place one freezing box 220 in the horizontal first direction, and any two first placement cavities 210 are not arranged along the horizontal first direction, so that the process of taking and placing the freezing rack is simple, and the pick-and-place mechanism is easy to operate, thereby avoiding the risk of failure in a low-temperature environment due to a complex structure.
[0026] The biological sample freezing device 10 may include a refrigerator, a freezer, a cold storage, a liquid nitrogen tank, etc., which is not limited in this embodiment.
[0027] The cavity 100 may include a box, a cabinet, a storage body, a tank, etc. The freezing rack (the first freezing rack 200 and the second freezing rack 400 described later) may be fixed to the accommodating cavity 110 by various means such as bolts, pins, welding, etc., and may be directly fixed to the cavity 100 or indirectly fixed to the cavity 100 through an intermediate device. The freezing rack may also be movably arranged in the accommodating cavity 110. The freezing rack may be in various shapes such as a rectangle and a semicircle.
[0028] The cryopreservation box 220 can be provided with a hole to place a cryopreservation tube or a cryopreservation bag containing a biological sample. The pick-up and placement device 300 can be a clamping claw, so that the cryopreservation box 220 can be taken and placed by clamping the cryopreservation box 220. The pick-up and placement device 300 can be a hook, so that the cryopreservation box 220 can be taken and placed by hooking the cryopreservation box 220. The pick-up and placement device 300 can also be an adsorption device, so that the cryopreservation box 220 can be taken and placed by adsorbing the cryopreservation box 220. The pick-up and placement device 300 can be a shovel plate, so that the cryopreservation box 220 can be taken and placed by shoveling the cryopreservation box 220. The pick-up and placement device 300 can be arranged in the accommodation cavity 110, or can be arranged outside the accommodation cavity 110 through a supporting structure, a suspension mechanism, etc., and this embodiment does not limit this. Multiple pick-up and placement devices 300 can take and place different cryopreservation boxes 220 in the same placement cavity, or can take and place cryopreservation boxes 220 in different placement cavities, and this embodiment does not limit this. The pick-and-place device 300 can be moved in various ways such as a gantry, a track, etc. Such structures are well known to those skilled in the art and will not be described in detail in this embodiment.
[0029] The first freezing rack 200 may define a plurality of first placement chambers 210 through partitions. When the taking and placing device 300 is disposed outside the receiving chamber 110 , the freezing box 220 may be taken and placed when the opening of the receiving chamber 110 is opened.
[0030] In some embodiments, the first placement cavity 210 has an opening at a first end in the horizontal first direction.
[0031] The biological sample freezing device 10 may further include a second freezing rack 400, which is disposed in the accommodating chamber 110. The second freezing rack 400 defines a plurality of second placement chambers 410. The second placement chamber 410 has an opening at the second end in the horizontal first direction. The second placement chamber 410 is only used to place one freezing box 220 in the horizontal first direction. The freezing box 220 is used to store biological samples. Any two of the second placement chambers 410 are not arranged along the horizontal first direction.
[0032] The first freezing rack 200 and the second freezing rack 400 are provided at the same time to facilitate their arrangement in the receiving chamber 110 , thereby increasing the diversity of space utilization.
[0033] In some specific embodiments, the first end of the second freezing rack 400 in the horizontal first direction is fixedly connected and fitted to the second end of the first freezing rack 200 in the horizontal first direction (e.g. Figure 3 as shown) or interval settings.
[0034] In some embodiments, all the first placement cavities 210 of the first freezing rack 200 are arranged along a vertical plane, and / or all the second placement cavities 410 of the second freezing rack 400 are arranged along a vertical plane, specifically, they can be arranged along a rectangular array, then the first freezing rack 200 and / or the second freezing rack 400 are rectangular freezing racks. In other embodiments, the first freezing rack 200 and / or the second freezing rack 400 are semicircular freezing racks, for example, the first freezing rack 200 and the second freezing rack 400 can both be semicircular freezing racks, then the first freezing rack 200 and the second freezing rack 400 are combined into a circular freezing rack, the first freezing rack 200 and the second freezing rack 400 can be arranged at intervals, then the center of the circular freezing rack has a central cavity, the placement device 300 can be arranged in the central cavity, or can be arranged outside the central cavity, the circular freezing rack can be a plurality of nested ones, and the circular freezing rack can be integrally formed, or can be formed by combining the first freezing rack 200 and the second freezing rack 400 by welding or the like.
[0035] In some embodiments, the first end of the second placement cavity 410 in the horizontal first direction is closed, thereby preventing the freezing box 220 from falling.
[0036] In some embodiments, the first end of the second placement cavity 410 in the horizontal first direction is attached to or fixed to the inner wall of the accommodating cavity 110. Thus, the space utilization rate can be improved.
[0037] In some embodiments, the second end of the first placement cavity 210 in the horizontal first direction is closed, thereby preventing the freezing box 220 from falling.
[0038] In some embodiments, the second end of the first placement cavity 210 in the horizontal first direction is attached to or fixed to the inner wall of the accommodating cavity 110. In this way, the space utilization rate can be improved.
[0039] The first freezing rack 200 is movably disposed in the receiving chamber 110, and / or the placing and taking device 300 is movably disposed inside or outside the receiving chamber 110. In addition, the second freezing rack 400 can also be movably disposed in the receiving chamber 110, and the freezing rack can be moved by various means such as slide rails, rollers, and push rods, and the placing and taking device 300 can be moved by various means such as slide rails and gantry frames.
[0040] In some embodiments, the cavity 100 includes an inner liner defining the accommodating cavity 110 and a shell disposed outside the inner liner, and a heat preservation device is disposed between the inner liner and the shell. The heat preservation device can be foaming, bathing, etc., thereby improving the heat preservation effect of the cavity 100.
[0041] Regarding the embodiments of the present application, it should also be noted that, in the absence of conflict, the embodiments of the present application and the features therein can be combined with each other to obtain new embodiments.
[0042] The above are only specific implementation methods of the present application, but the protection scope of the present application is not limited thereto. The protection scope of the present application shall be based on the protection scope of the claims.
Claims
1. A biological sample freezing device, characterized in that: include: a cavity, wherein the cavity defines a receiving cavity; a first freezing rack, the first freezing rack being arranged in the accommodating chamber, the first freezing rack defining a plurality of first placement chambers, the first placement chambers having an opening at at least one end in a first horizontal direction, the first placement chamber being used to place only one freezing box in the first horizontal direction, the freezing box being used to store biological samples, and any two of the first placement chambers being not arranged along the first horizontal direction; A taking and placing device is arranged inside or outside the accommodating cavity, and is used to take and place the freezing box through the opening.
2. The biological sample freezing device according to claim 1, characterized in that: The first placement cavity has an opening at a first end in the horizontal first direction.
3. The biological sample freezing device according to claim 2, characterized in that: Also includes: A second freezing rack, the second freezing rack is arranged in the accommodating cavity, the second freezing rack defines a plurality of second placement cavities, the second placement cavity has an opening at the second end in the horizontal first direction, the second placement cavity is only used to place one freezing box in the horizontal first direction, the freezing box is used to store biological samples, and any two of the second placement cavities are not arranged along the horizontal first direction.
4. The biological sample freezing device according to claim 3, characterized in that: The first end of the second freezing rack in the first horizontal direction is fixedly connected, closely fitted or spaced from the second end of the first freezing rack in the first horizontal direction.
5. The biological sample freezing device according to claim 3, characterized in that: The second placement cavity is closed at a first end in the horizontal first direction.
6. The biological sample freezing device according to claim 3, characterized in that: A first end of the second placement cavity in the horizontal first direction is attached to or fixed to the inner wall of the accommodating cavity.
7. The biological sample freezing device according to claim 2, characterized in that: The first placement cavity is closed at a second end in the horizontal first direction.
8. The biological sample freezing device according to claim 2, characterized in that: The second end of the first placement cavity in the horizontal first direction is attached to or fixed to the inner wall of the accommodating cavity.
9. The biological sample freezing device according to claim 1, characterized in that: The first freezing rack is movably disposed in the accommodating chamber, and / or the taking and placing device is movably disposed inside or outside the accommodating chamber.
10. The biological sample freezing device according to claim 1, characterized in that: The cavity comprises an inner liner defining the accommodating cavity and a shell arranged outside the inner liner, and a heat preservation device is arranged between the inner liner and the shell.