Critical temperature label components and pharmaceutical packaging

Abstract

The utility model discloses a critical temperature label assembly and medicine packaging, wherein the critical temperature label assembly includes a first label, the first label includes a first substrate layer and a first adhesive layer that are stacked, the first adhesive layer is made of a polyurethane adhesive material with a specific glass transition temperature Tg, when the ambient temperature is higher than the glass transition temperature Tg, the polyurethane adhesive material is in a glass state and has a high adhesive force, when the ambient temperature is lower than the glass transition temperature Tg, the polyurethane adhesive material is in a crystalline state, and the adhesive force is greatly reduced. For the above critical temperature label assembly, when the ambient temperature is higher than its glass transition temperature Tg, the polyurethane adhesive material is in a glass state and has a high adhesive force, and can be attached to the surface of an object through the adhesive force; when the ambient temperature is lower than its glass transition temperature Tg, the polyurethane adhesive material is in a crystalline state, and the adhesive force is greatly reduced, so that the label assembly can fall off the surface of the object under the action of gravity.

Description

Technical Field

[0001] The utility model relates to the technical field of labels, in particular to a critical temperature label component and medicine packaging. Background Art

[0002] As we all know, most vaccines, sera and other biological products need to be stored in an environment of 2-8°C. When the ambient temperature is higher than the upper limit of 8°C or lower than the lower limit of 2°C, the biological products will quickly lose their activity. Therefore, it is necessary to test the storage temperature of biological products.

[0003] In the prior art, there are a large number of color-changing labels that can detect the upper temperature limit, but there are very few labels that can detect the lower temperature limit, and the structure is complex and the cost is high.

[0004] Therefore, it is necessary to provide a critical temperature label assembly and a medicine package to solve the above problems. Utility Model Content

[0005] A first aspect of the present invention provides a critical temperature label assembly.

[0006] A critical temperature label assembly comprises a first label, wherein the first label comprises a first substrate layer and a first adhesive layer which are stacked, wherein the first adhesive layer is made of a polyurethane adhesive material having a specific glass transition temperature Tg, and when the ambient temperature is higher than the glass transition temperature Tg, the polyurethane adhesive material is in a glassy state and has a high adhesive force, and when the ambient temperature is lower than the glass transition temperature Tg, the polyurethane adhesive material is in a crystalline state and the adhesive force is greatly reduced.

[0007] In one embodiment, the first substrate layer is selected from any one of PP film, PET film, PVC film or paper.

[0008] In one embodiment, the glass transition temperature Tg is 2°C or 0°C.

[0009] In one embodiment, the first substrate layer is provided with first warning information.

[0010] In one embodiment, the first warning information is a color block or text information.

[0011] In one embodiment, the second label is further included. The second label is stacked below the first label. The second label includes a second substrate layer, a second adhesive layer, and a release layer that are stacked.

[0012] In one embodiment, second warning information is provided on the second substrate layer.

[0013] In one embodiment, the area of ​​the second label is larger than the area of ​​the first label.

[0014] The above-mentioned critical temperature label assembly, the first adhesive layer is made of a polyurethane adhesive material, the polyurethane adhesive material has a specific glass transition temperature Tg, when the ambient temperature is higher than its glass transition temperature Tg, the polyurethane adhesive material is in a glassy state, has a high adhesive force, and can be attached to the surface of the object through the adhesive force; when the ambient temperature is lower than its glass transition temperature Tg, the polyurethane adhesive material is in a crystalline state, the adhesive force is greatly weakened, so that the label assembly can fall off the surface of the object under the action of gravity.

[0015] A second aspect of the utility model provides a medicine package.

[0016] A medicine package comprises a package body and a critical temperature label assembly arranged on the package body, wherein the critical temperature label assembly is any one of the critical temperature label assemblies provided in the first aspect of the utility model.

[0017] In one embodiment, the packaging body is in the shape of a hexahedron or a cylinder. BRIEF DESCRIPTION OF THE DRAWINGS

[0018] Figure 1 is a schematic diagram of a critical temperature tag assembly according to one embodiment;

[0019] Figure 2 is a schematic diagram of a critical temperature tag assembly according to another embodiment;

[0020] Figure 3 A pharmaceutical packaging according to an embodiment;

[0021] Figure 4 This is another embodiment of a pharmaceutical packaging. DETAILED DESCRIPTION

[0022] In order to make the above-mentioned purposes, features and advantages of the utility model more obvious and easy to understand, the specific implementation methods of the utility model are described in detail below in conjunction with the accompanying drawings. In the following description, many specific details are set forth to facilitate a full understanding of the utility model. However, the utility model can be implemented in many other ways different from those described herein, and those skilled in the art can make similar improvements without violating the connotation of the utility model. Therefore, the utility model is not limited by the specific implementation methods disclosed below.

[0023] It should be noted that when an element is referred to as being "fixed to" another element, it may be directly on the other element or there may be a central element. When an element is considered to be "connected" or "communicated" with another element, it may be directly connected to the other element or there may be a central element at the same time. The terms "upper", "lower", "vertical", "horizontal", "left", "right" and similar expressions used herein are for illustrative purposes only and are not intended to be the only implementation method.

[0024] The critical temperature label and drug packaging are further described in detail below mainly in conjunction with the accompanying drawings and specific embodiments.

[0025] A critical temperature label assembly 1 of one embodiment, see Figure 1 The critical temperature label assembly 1 includes a first label 10 , and the first label 10 includes a first substrate layer 11 and a first adhesive layer 12 which are stacked.

[0026] The first substrate layer 11 is used to support the first adhesive layer 12. At the same time, the first substrate layer 11 can fall off from the first adhesive layer 12 by its own gravity when the first adhesive layer 12 changes from a glass state to a crystalline state, thereby playing a warning role.

[0027] Preferably, the first substrate layer 11 has a certain elastic deformation ability. When the first substrate layer 11 is attached to the surface of a curved object along with the first adhesive layer 12 and deforms accordingly, a predetermined amount of elastic torque can be generated at both ends of the first substrate layer 11. The elastic torque can restore the first substrate layer 11 from a curved state to a straight state when the first adhesive layer 12 changes from a glass state to a crystalline state. At this time, the contact area between the first substrate layer 11 and the curved object surface is greatly reduced, further reducing the bonding force between the first substrate layer 11 and the first adhesive layer 12, which is conducive to the first substrate layer 11 falling off from the surface of the object by its own gravity, thereby playing a warning role.

[0028] The two factors that affect the magnitude of the elastic moment of the first substrate layer 11 include: (1) the thickness of the first substrate layer 11. When the length of the force arm remains unchanged, the thicker the first substrate layer 11 is, the greater the elastic moment it generates. (2) the length of the force arm of the first substrate layer 11. When the magnitude of the elastic force remains unchanged, the greater the length of the force arm of the first substrate layer 11 is, the greater the elastic moment it generates.

[0029] Optionally, the thickness of the first substrate layer 11 is 50 micrometers to 100 micrometers. The material of the first substrate layer 11 within this thickness range is widely used in the packaging industry and has the characteristic of low cost.

[0030] Optionally, the first substrate layer 11 includes but is not limited to: PP film, PET film, PVC film or paper.

[0031] Preferably, the first substrate layer 11 has a smooth surface. The smooth surface can ensure that the molecules of the first adhesive layer 12 will not penetrate into the first substrate layer 11. The two are only connected by hydrogen bonds. When the first adhesive layer 12 changes from a glassy state to a crystalline state, the hydrogen bonds can be easily destroyed, thereby causing the bonding force between the first adhesive layer 12 and the first substrate layer 11 to be greatly reduced, thereby causing the first substrate layer 11 to fall off from the first adhesive layer 12.

[0032] In this embodiment, the upper surface of the first substrate layer 11 is provided with first warning information, and the first warning information is used to prompt that the ambient temperature is in a safe state.

[0033] Optionally, the first warning information is a color block or text information.

[0034] The first adhesive layer 12 is laminated below the first substrate layer 11 . The first adhesive layer 12 is sticky and can adhere to the first substrate layer 11 and the surface of an object through bonding force.

[0035] Specifically, the first adhesive layer 12 is made of a polyurethane adhesive material having a specific glass transition temperature Tg. When the ambient temperature is higher than its glass transition temperature Tg, the polyurethane adhesive material is in a glassy state and has a high adhesive force, so that the critical temperature label component 1 can be attached to the surface of the object through the adhesive force; when the ambient temperature is lower than its glass transition temperature Tg, the polyurethane adhesive material is in a crystalline state. Compared with the glassy polyurethane adhesive material, the adhesive force of the crystalline polyurethane adhesive material is greatly weakened, so that the label component or the first substrate layer 11 can fall off from the surface of the object under the action of its own gravity.

[0036] The invention patent application with the publication number CN110627985A discloses a polylactic acid-based thermoplastic polyurethane elastomer material and its preparation method. It can be known from the records in paragraphs 0025 and 0084 of the specification that the soft segment of the polyurethane elastomer is polylactic acid diol, and the hard segment includes diisocyanate compounds and small molecule diols. In the preparation process, polylactic acid diols (PLA) with different molecular weights are used as soft segments, diisocyanate and small molecule diols are used as hard segments, and by changing the molar ratio of the two, a thermoplastic polylactic acid-based polyurethane elastomer with a glass transition temperature Tg between -15 and 3.6°C can be prepared. Thermoplastic polylactic acid-based polyurethane elastomer with a glass transition temperature Tg in this range is particularly suitable as the material of the first adhesive layer 12 of the utility model.

[0037] Optionally, the glass transition temperature Tg is 0°C. 0°C is the freezing point of water at normal pressure, and it is of great significance to warn about this temperature value.

[0038] Preferably, the glass transition temperature Tg is 2°C, which is the lower storage temperature limit for most biological products. The critical temperature label component 1 prepared using this glass transition temperature has a wide range of uses in the field of biological products.

[0039] In another embodiment, see Figure 2 The critical temperature label assembly 1 further includes a second label 20 , which is stacked below the first label 10 .

[0040] Specifically, the second label 20 is made of a common self-adhesive material, and includes a second substrate layer 21, a second adhesive layer 22, and a release layer 23, which are stacked. The second substrate layer 21 is provided with a second warning message. When the ambient temperature is higher than the glass transition temperature Tg of the first adhesive layer 12, the first label 10 is firmly attached to the second label 20. At this time, the user can see the first warning message provided above the first substrate layer 11, while the second warning message provided below the first label 10 is in a shielded state. When the ambient temperature is lower than the glass transition temperature Tg of the first adhesive layer 12, the first label 10 falls off from the second label 20. At this time, the second warning message is in an exposed state, and people can be warned through the second warning message: the ambient temperature has been lower than the lower limit of the storage temperature.

[0041] Optionally, the second warning information is a color block or text information.

[0042] Preferably, the area of ​​the second label 20 is larger than that of the first label 10, and the second warning information is arranged at the projection of the first label 10 on the second substrate layer 21. By increasing the area of ​​the second label 20, it helps to increase the information carrying capacity of the critical temperature label assembly 1.

[0043] In addition, by setting the second label 20, the following beneficial effects can be brought about: when the user sees only the second label 20 but no first label 10 on the product, it can be determined that the first label 10 fell off because the storage temperature was lower than the lower limit of the temperature, and not because of missing label.

[0044] In the above-mentioned critical temperature label assembly 1, the first adhesive layer 12 is made of a polyurethane adhesive material, and the polyurethane adhesive material has a specific glass transition temperature Tg. When the ambient temperature is higher than its glass transition temperature Tg, the polyurethane adhesive material is in a glassy state and has a high adhesive force, and can be attached to the surface of an object through the adhesive force; when the ambient temperature is lower than its glass transition temperature Tg, the polyurethane adhesive material is in a crystalline state, and the adhesive force is greatly weakened, so that the critical temperature label assembly 1 or the first substrate layer 11 can fall off from the surface of the object under the action of gravity.

[0045] For a pharmaceutical packaging according to an embodiment of the present invention, please refer to Figure 3, which includes a packaging body 2 and a critical temperature label assembly 1 attached to the packaging body 2, wherein the critical temperature label assembly 1 is any one of the critical temperature label assemblies 1 provided in the first aspect of the utility model.

[0046] In this embodiment, the packaging body 2 is a hexahedral packaging box, and the material of the packaging box can be paper or other materials. It should be understood that packaging boxes of other shapes can also be used as the packaging body 2 of the present utility model.

[0047] In another embodiment, see Figure 4 The packaging body 2 is a cylindrical glass bottle, which can be a vial or an ampoule.

[0048] The above-mentioned pharmaceutical packaging includes a critical temperature label component 1. The first adhesive layer 12 of the critical temperature label component 1 is made of a polyurethane adhesive material. The polyurethane adhesive material has a specific glass transition temperature Tg. When the ambient temperature is higher than its glass transition temperature Tg, the polyurethane adhesive material is in a glassy state and has a high adhesive force, and can be attached to the surface of an object through the adhesive force; when the ambient temperature is lower than its glass transition temperature Tg, the polyurethane adhesive material is in a crystalline state, and the adhesive force is greatly weakened, so that the label component or the first substrate layer 11 can fall off from the surface of the object under the action of gravity.

[0049] The following are specific embodiments.

[0050] Example 1

[0051] The first aspect of this embodiment provides a critical temperature label assembly 1, see Figure 1 The critical temperature label assembly 1 comprises a first label 10, and the first label 10 comprises a first substrate layer 11 and a first adhesive layer 12 which are stacked. In this embodiment, the first substrate layer 11 is a PVC film, and the first adhesive layer 12 is a polyurethane adhesive material with a glass transition temperature Tg of 2°C.

[0052] In the above-mentioned critical temperature label assembly 1, the first adhesive layer 12 is made of a polyurethane adhesive material, and the polyurethane adhesive material has a specific glass transition temperature Tg. When the ambient temperature is higher than its glass transition temperature Tg, the polyurethane adhesive material is in a glassy state and has a high adhesive force, and can be attached to the surface of an object through the adhesive force; when the ambient temperature is lower than its glass transition temperature Tg, the polyurethane adhesive material is in a crystalline state, and the adhesive force is greatly weakened, so that the label assembly or the first substrate layer 11 can fall off from the surface of the object under the action of gravity.

[0053] The second aspect of this embodiment also provides a medicine packaging. Figure 3The pharmaceutical packaging includes a packaging body 2 and a critical temperature label assembly 1 arranged on the packaging body 2. In this embodiment, the packaging body 2 is a hexahedral paper packaging box, and the critical temperature label assembly 1 is the critical temperature label assembly 1 provided in the first aspect of this embodiment.

[0054] Example 2

[0055] See also Figure 2 In a first aspect of the present embodiment, a critical temperature label assembly 1 is provided, which includes a first label 10 and a second label 20 which are stacked, wherein the first label 10 includes a first substrate layer 11 and a first adhesive layer 12 which are stacked, and the upper surface of the first substrate layer 11 is provided with first warning information, and the second label 20 includes a second substrate layer 21, a second adhesive layer 22 and a release layer 23 which are stacked, and the second substrate layer 21 is provided with second warning information.

[0056] In this embodiment, the area of ​​the second label 20 is larger than that of the first label 10 , the first substrate layer 11 is a PET film, and the first adhesive layer 12 is a polyurethane adhesive material with a glass transition temperature Tg of 0° C.

[0057] The critical temperature label assembly 1 helps to increase the information carrying capacity by increasing the area of ​​the second label 20. In addition, by providing the second label 20, the following beneficial effects can be brought about: when the user sees only the second label 20 but no first label 10 on the product in the cold chain, it can be determined that the first label 10 fell off because the storage temperature was lower than the lower critical value, not because of missing label.

[0058] See also Figure 4 This embodiment also provides a drug package, which includes a package body 2 and a critical temperature label assembly 1 arranged on the package body 2.

[0059] In this embodiment, the packaging body 2 is a cylindrical vial, and the critical temperature label assembly 1 is the critical temperature label assembly 1 provided in the first aspect of this embodiment.

[0060] The above-mentioned embodiments only express several implementation methods of the utility model, and the description is relatively specific and detailed, but it cannot be understood as limiting the scope of the utility model patent. It should be pointed out that for ordinary technicians in this field, several modifications and improvements can be made without departing from the concept of the utility model, which all belong to the protection scope of the utility model. Therefore, the protection scope of the utility model patent shall be based on the attached claims.

Claims

1. A critical temperature label assembly, characterized in that: The invention comprises a first label, wherein the first label comprises a first substrate layer and a first adhesive layer which are stacked, wherein the first adhesive layer is made of a polyurethane adhesive material having a specific glass transition temperature Tg, and when the ambient temperature is higher than the glass transition temperature Tg, the polyurethane adhesive material is in a glassy state and has a high adhesive force, and when the ambient temperature is lower than the glass transition temperature Tg, the polyurethane adhesive material is in a crystalline state and the adhesive force is greatly reduced.

2. The critical temperature label assembly according to claim 1, characterized in that: The first substrate layer is selected from any one of PP film, PET film, PVC film or paper.

3. The critical temperature label assembly according to claim 2, characterized in that: The glass transition temperature Tg is 2°C or 0°C.

4. The critical temperature label assembly according to claim 3, characterized in that: The first substrate layer is provided with first warning information.

5. The critical temperature label assembly according to claim 4, characterized in that: The first warning information is a color block or text information.

6. The critical temperature label assembly according to any one of claims 1 to 5, characterized in that: The invention also comprises a second label, wherein the second label is stacked below the first label, and the second label comprises a second substrate layer, a second adhesive layer and a release layer which are stacked.

7. The critical temperature label assembly according to claim 6, characterized in that: The second substrate layer is provided with second warning information.

8. The critical temperature label assembly according to claim 7, characterized in that: The area of ​​the second label is larger than that of the first label.

9. A medicine package, characterized in that: It comprises a packaging body and a critical temperature label assembly arranged on the packaging body, and the critical temperature label assembly is the critical temperature label assembly according to any one of claims 1-8.

10. The drug packaging according to claim 9, characterized in that: The packaging body is in the shape of a hexahedron or a cylinder.

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