Antigen-antibody reaction kit

By designing an antigen antibody reaction box including the reaction box body and the lid, the contamination problem caused by improper operation in the prior art is solved, and a safer and more convenient experimental operation is achieved.

CN222748590UActive Publication Date: 2025-04-11SUZHOU RUI YING BIOTECHNOLOGY CO LTD
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Patent Information

Application Number
CN202420849189.0
Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
Filing Date
2024-04-23
Publication Date
2025-04-11
Estimated Expiration
2034-04-23

AI Technical Summary

Technical Problem

When using the existing antigen antibody reaction box, improper operation can easily lead to incomplete cutting of the protective film or fragments falling into the container, affecting subsequent operations, and making troublesome operations and unable to meet people's needs.

Method used

An antigen antibody reaction box is designed, including the reaction box body and the box cover. The box cover forms a threaded structure through the through hole and the threaded plug, the protrusion forms an elastic structure through the spring and the round block, and the sealing groove and the sealing ring strengthen the sealing effect, allowing the injection of antigen antibodies through the through hole to avoid the risk of contamination when removing the box cover.

Benefits of technology

The antigen antibody reaction box with simple operation and easy-to-use operation is realized, which enhances the sealing effect between the box cover and the reaction box body, avoids the risk of contamination, and makes the experimental process safer and more convenient.

✦ Generated by Eureka AI based on patent content.

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Abstract

The utility model relates to the technical field of antigen-antibody detection, and discloses an antigen-antibody reaction box, including a storage box, a placement groove is provided on the top of the storage box, and a rubber sleeve is fixedly connected inside the placement groove. The antigen-antibody reaction box can inject antigens and antibodies into the reaction box body by disassembling the box cover from the reaction box body, and the operation is simple and convenient to use. The box cover is assembled with the reaction box body, and the round block is pressed against the reaction box body by the elastic force of the spring, so that the box cover is assembled more stably. By providing a sealing ring, the sealing effect between the box cover and the reaction box body is strengthened. When it is necessary to add antigens and antibodies midway, it is not necessary to disassemble the box cover, disassemble the threaded plug, and use a dropper to inject the antigens and antibodies into the reaction box body through the through hole, avoiding the risk of contamination caused by exposing a large opening due to disassembling the box cover, making the experimental process safer and more convenient, and meeting people's needs.
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Description

Technical Field

[0001] The utility model relates to the technical field of antigen and antibody detection, in particular to an antigen and antibody reaction box. Background Art

[0002] When doing protein immunoblotting experiments, the antigen-antibody binding reaction between the primary antibody and the protein on the cellulose acetate membrane carrying the protein antigen is a key step in determining the success or failure of detecting the presence of a certain protein; the antigen-antibody reaction is generally carried out in an antigen-antibody reaction box to facilitate the full binding of the antigen and antibody.

[0003] The prior art patent document with publication number CN216209186U provides an antigen-antibody reaction box, which is provided with a plurality of reaction containers on a reaction substrate, and a protective film is covered on the reaction substrate at the end face of the open end of the reaction container for protection. When the corresponding reaction container is needed, the protective film at the corresponding reaction container can be destroyed, thereby avoiding contamination of the interior of the reaction container at adjacent or other positions during use.

[0004] Although the above-mentioned prior art has a protective film on the container to ensure its sealing, when using it, when putting antigens and antibodies into the container, it is necessary to use a knife to destroy the protective film. If the operation is improper, the protective film will not be cut completely or fragments will fall into the container, which will affect subsequent operations. It is very inconvenient and troublesome to operate, and cannot meet people's needs. Therefore, we need an antigen-antibody reaction box. Utility Model Content

[0005] The purpose of the utility model is to provide an antigen-antibody reaction box to solve the problems raised in the above background technology.

[0006] In order to solve the above technical problems, the utility model provides the following technical solutions: an antigen-antibody reaction box, comprising a storage box, a placement groove is provided on the top of the storage box, and a rubber sleeve is fixedly connected to the inside of the placement groove, a box body component is arranged inside the rubber sleeve, and a marking component is arranged on the outer wall of the box body component, a supporting foot is fixedly connected to the bottom of the storage box, and a rubber pad is fixedly connected to the bottom of the supporting foot;

[0007] The box body assembly includes a reaction box body, and a box cover is arranged on the top of the reaction box body, a protrusion is fixedly connected to the inner wall of the box cover, and a through hole is opened on the top of the box cover, a threaded plug is threadedly connected to the inner wall of the through hole, a circular groove is opened on the outer wall of the protrusion, and a spring is fixedly connected to the inner wall of the circular groove, a round block is fixedly connected to one end of the spring, a sealing groove is opened on the outer wall of the protrusion, and a sealing ring is arranged on the inner wall of the sealing groove;

[0008] The identification component comprises a placement box, and the outer wall of the placement box is provided with fixing bolts, the top of the placement box is provided with a slot, and the inner wall of the placement box is fixedly connected with a visual window, and the inner wall of the slot is slidably connected with an identification card.

[0009] Preferably, the shape and size of the protrusion match the shape and size of the reaction box body, and one end of the protrusion extends into the reaction box body for connection.

[0010] Preferably, the box cover forms a threaded structure with the threaded plug through the through hole, and one end of the threaded plug is threadedly inserted into the through hole for connection.

[0011] Preferably, the protrusion forms an elastic structure with the round block through a spring, and one end of the round block extends into the circular groove to be connected with the spring.

[0012] Preferably, the shape and size of the inner wall of the sealing groove matches the shape and size of the outer wall of the sealing ring, and the inner wall of the sealing groove fits the outer wall of the sealing ring.

[0013] Preferably, the reaction box body forms a fixed structure with the placement box through a fixing bolt, and one end of the fixing bolt is threadedly passed through the placement box and extends into the reaction box body for connection.

[0014] Preferably, the placement box and the identification card form a sliding structure through a slot, and one end of the identification card extends into the slot for connection.

[0015] Compared with the prior art, the beneficial effects achieved by the utility model are:

[0016] First, the utility model is provided with a reaction box body, a box cover, a protrusion, a through hole, a threaded plug, a round groove, a spring, a round block, a sealing groove and a sealing ring. By removing the box cover from the reaction box body, the antigen and antibody can be injected into the reaction box body. The operation is simple and easy to use. The box cover is assembled with the reaction box body, and the round block is pressed against the reaction box body by the elastic force of the spring, so that the box cover is assembled more stably. By providing a sealing ring, the sealing effect between the box cover and the reaction box body is strengthened. When it is necessary to add antigens and antibodies midway, there is no need to remove the box cover, but to remove the threaded plug, and use a dropper to inject the antigens and antibodies into the reaction box body through the through hole, thereby avoiding the risk of contamination caused by exposing a large hole due to removing the box cover, making the experimental process safer and more convenient, and meeting people's needs.

[0017] Second, the utility model is provided with a placement box, fixing bolts, slots, a visual window and an identification card. By providing the identification card, the experimenter can record the relevant information of the antigen and antibody on the identification card, and can directly see the information on the identification card through the visual window, which is convenient for searching. By providing each reaction box body with an identification card that matches it, the experimenter can more easily manage multiple reaction box bodies, which is convenient for using multiple reaction box bodies to conduct multiple experiments. The structure is simple and easy to use. BRIEF DESCRIPTION OF THE DRAWINGS

[0018] Figure 1 This is a schematic diagram of the main structure of the utility model;

[0019] Figure 2 This is a schematic diagram of the structure of the rubber sleeve and the reaction box body of the utility model;

[0020] Figure 3 For this utility model Figure 2 The enlarged structural diagram at A in the middle;

[0021] Figure 4 It is a schematic diagram of the structure of the reaction box body and the placement box of the utility model.

[0022] Among them: 1. Storage box; 2. Placement slot; 3. Rubber sleeve; 4. Box body assembly; 401. Reaction box body; 402. Box cover; 403. Protrusion; 404. Through hole; 405. Threaded plug; 406. Round groove; 407. Spring; 408. Round block; 409. Sealing groove; 410. Sealing ring; 5. Identification assembly; 501. Placement box; 502. Fixing bolt; 503. Slot; 504. Visual window; 505. Identification card; 6. Support foot; 7. Rubber pad. DETAILED DESCRIPTION

[0023] The following will be combined with the drawings in the embodiments of the utility model to clearly and completely describe the technical solutions in the embodiments of the utility model. Obviously, the described embodiments are only part of the embodiments of the utility model, not all of the embodiments. Based on the embodiments in the utility model, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the utility model.

[0024] See also Figure 1 , Figure 2 , Figure 3 and Figure 4, an antigen-antibody reaction box, comprising a storage box 1, a placement slot 2 is provided on the top of the storage box 1, and a rubber sleeve 3 is fixedly connected to the inside of the placement slot 2, a box body component 4 is arranged inside the rubber sleeve 3, and an identification component 5 is arranged on the outer wall of the box body component 4, a supporting foot 6 is fixedly connected to the bottom of the storage box 1, and a rubber pad 7 is fixedly connected to the bottom of the supporting foot 6; the box body component 4 comprises a reaction box body 401, and a box cover 402 is provided on the top of the reaction box body 401, a protrusion 403 is fixedly connected to the inner wall of the box cover 402, and a through hole 404 is provided on the top of the box cover 402, and the inner wall of the through hole 404 is provided with a protrusion 403. A threaded plug 405 is connected to the wall thread, a circular groove 406 is provided on the outer wall of the protrusion 403, and a spring 407 is fixedly connected to the inner wall of the circular groove 406, a round block 408 is fixedly connected to one end of the spring 407, a sealing groove 409 is provided on the outer wall of the protrusion 403, and a sealing ring 410 is provided on the inner wall of the sealing groove 409; the identification component 5 includes a placement box 501, and a fixing bolt 502 is provided on the outer wall of the placement box 501, a slot 503 is provided on the top of the placement box 501, and a visual window 504 is fixedly connected to the inner wall of the placement box 501, and an identification card 505 is slidably connected to the inner wall of the slot 503.

[0025] Through the above technical solution, the antigen and antibody can be injected into the reaction box body 401 by removing the box cover 402 from the reaction box body 401. The operation is simple and easy to use. The box cover 402 is assembled with the reaction box body 401, and the round block 408 is pressed against the reaction box body 401 by the elastic force of the spring 407, so that the assembly of the box cover 402 is more stable. The sealing effect between the box cover 402 and the reaction box body 401 is strengthened by providing a sealing ring 410. When it is necessary to add antigens and antibodies midway, there is no need to remove the box cover 402, but to remove the threaded plug 405, and use a dropper to inject the antigens and antibodies into the reaction box body 401 through the through hole 404, thereby avoiding the risk of contamination caused by the large opening exposed due to the removal of the box cover 402, making the experiment more convenient. The process is safer and more convenient, meeting people's needs. The experimenter can record relevant information of antigen and antibody on the identification card 505, and can directly see the information on the identification card 505 through the visual window 504, which is convenient for searching. By setting a matching identification card 505 for each reaction box body 401, the experimenter can more easily manage multiple reaction box bodies 401, and it is convenient to use multiple reaction box bodies 401 to conduct multiple experiments. The structure is simple and easy to use. By providing a rubber sleeve 3, the reaction box body 401 can be inserted into the rubber sleeve 3 more stably, which is convenient for the operator to remove and put in the reaction box body 401. The storage box 1 can be well supported by four supporting feet 6, and the anti-slip effect is enhanced by providing a rubber pad 7.

[0026] Specifically, the shape and size of the protrusion 403 match the shape and size of the reaction box body 401, and one end of the protrusion 403 extends into the reaction box body 401 for connection.

[0027] Through the above technical solution, the connection effect between the protrusion 403 and the reaction box body 401 is strengthened, one end of the protrusion 403 on the box cover 402 extends into the reaction box body 401, and the sealing effect is strengthened by the provided sealing ring 410.

[0028] Specifically, the box cover 402 forms a threaded structure with the threaded plug 405 through the through hole 404, and one end of the threaded plug 405 is threadedly extended into the through hole 404 for connection.

[0029] Through the above technical solution, the connection effect between the box cover 402 and the through hole 404 and the threaded plug 405 is strengthened. An internal thread is provided on the inner wall of the through hole 404, and the internal thread matches the external thread at one end of the threaded plug 405, which facilitates the installation and removal of the threaded plug 405.

[0030] Specifically, the protrusion 403 forms an elastic structure with the round block 408 through the spring 407 , and one end of the round block 408 extends into the circular groove 406 to be connected with the spring 407 .

[0031] Through the above technical solution, the connection effect between the protrusion 403 and the spring 407 and the round block 408 is strengthened. When the box cover 402 is assembled on the reaction box body 401, the protrusion 403 extends into the reaction box body 401. During the insertion process, the inner wall of the reaction box body 401 squeezes the round block 408, and the movement of the round block 408 causes the spring 407 to contract. After the spring 407 contracts, it rebounds and drives the round block 408 to move. One end of the round block 408 presses against the reaction box body 401, thereby strengthening the stability of the assembly of the box cover 402 and the reaction box body 401.

[0032] Specifically, the shape and size of the inner wall of the sealing groove 409 match the shape and size of the outer wall of the sealing ring 410 , and the inner wall of the sealing groove 409 fits the outer wall of the sealing ring 410 .

[0033] Through the above technical solution, the connection effect between the sealing groove 409 and the sealing ring 410 is strengthened, the sealing effect is strengthened, and it is convenient to install the sealing ring 410 in the sealing groove 409.

[0034] Specifically, the reaction box body 401 forms a fixed structure with the placement box 501 through the fixing bolt 502, and one end of the fixing bolt 502 is threadedly passed through the placement box 501 and extends into the reaction box body 401 for connection.

[0035] Through the above technical solution, the connection effect between the reaction box body 401 and the fixing bolts 502 and the placement box 501 is strengthened. There are multiple fixing bolts 502, which can well fix the placement box 501 on the reaction box body 401, making it easy to install and disassemble.

[0036] Specifically, the placement box 501 forms a sliding structure with the identification card 505 through the slot 503, and one end of the identification card 505 extends into the slot 503 for connection.

[0037] Through the above technical solution, the connection effect between the placement box 501 and the slot 503 and the identification card 505 is strengthened, which makes it easier for operators to insert the identification card 505 into the slot 503 and facilitate insertion and removal.

[0038] When in use, first remove the box cover 402 on the reaction box body 401, then inject the antigen and antibody into the reaction box body 401, and cover the reaction box body 401 with the box cover 402. The round block 408 is pressed against the inner wall of the reaction box body 401 by the elastic force of the spring 407, so that the box cover 402 is assembled on the reaction box body 401 more stably. The sealing effect between the box cover 402 and the reaction box body 401 is strengthened by providing a sealing ring 410. When it is necessary to add antigens, antibodies or liquid medicine midway, the threaded plug 405 can be removed, and the antigens, antibodies or liquid medicine to be added can be sucked in with a dropper, and one end of the dropper is aligned with the through hole 404, and the dropper is pressed to inject the antigens, antibodies or liquid medicine into the reaction box body 401 through the through hole 404, thereby avoiding the large opening exposed due to the removal of the box cover 402. The risk of contamination is reduced, making the experimental process safer and more convenient, meeting people's needs. The experimenter can take out the identification card 505 from the slot 503 of the placement box 501, and record the relevant information of the antigen and antibody on the identification card 505. After the information is recorded, the identification card 505 can be inserted into the slot 503 of the placement box 501. The experimenter can directly see the information on the identification card 505 through the visual window 504, which is convenient for searching. By providing each reaction box body 401 with a matching identification card 505, the experimenter can more easily manage multiple reaction box bodies 401, which is convenient for using multiple reaction box bodies 401 for multiple experiments. The structure is simple and easy to use, which completes all the work. The content not described in detail in this specification belongs to the prior art known to professional and technical personnel in this field.

[0039] Although embodiments of the present invention have been shown and described, it will be appreciated by those skilled in the art that various changes, modifications, substitutions and variations may be made to the embodiments without departing from the principles and spirit of the present invention, and the scope of the invention is defined by the appended claims and their equivalents.

Claims

1. An antigen-antibody reaction box, comprising a storage box (1), characterized in that: The top of the storage box (1) is provided with a placement groove (2), and a rubber sleeve (3) is fixedly connected to the inside of the placement groove (2), a box body component (4) is arranged inside the rubber sleeve (3), and an identification component (5) is arranged on the outer wall of the box body component (4), and a supporting foot (6) is fixedly connected to the bottom of the storage box (1), and a rubber pad (7) is fixedly connected to the bottom of the supporting foot (6); The box body assembly (4) comprises a reaction box body (401), and a box cover (402) is arranged on the top of the reaction box body (401), a protrusion (403) is fixedly connected to the inner wall of the box cover (402), and a through hole (404) is provided on the top of the box cover (402), a threaded plug (405) is threadedly connected to the inner wall of the through hole (404), a circular groove (406) is provided on the outer wall of the protrusion (403), and a spring (407) is fixedly connected to the inner wall of the circular groove (406), and a round block (408) is fixedly connected to one end of the spring (407), and a sealing groove (409) is provided on the outer wall of the protrusion (403), and a sealing ring (410) is provided on the inner wall of the sealing groove (409); The identification component (5) comprises a placement box (501), wherein the outer wall of the placement box (501) is provided with a fixing bolt (502), a slot (503) is provided at the top of the placement box (501), and a visual window (504) is fixedly connected to the inner wall of the placement box (501), and an identification card (505) is slidably connected to the inner wall of the slot (503).

2. An antigen-antibody reaction kit according to claim 1, characterized in that: The shape and size of the protrusion (403) match the shape and size of the reaction box body (401), and one end of the protrusion (403) extends into the reaction box body (401) for connection.

3. An antigen-antibody reaction kit according to claim 1, characterized in that: The box cover (402) forms a threaded structure with the threaded plug (405) through the through hole (404), and one end of the threaded plug (405) is threadedly inserted into the through hole (404) for connection.

4. The antigen-antibody reaction kit according to claim 1, characterized in that: The protrusion (403) forms an elastic structure with the round block (408) through the spring (407), and one end of the round block (408) extends into the circular groove (406) to be connected with the spring (407).

5. The antigen-antibody reaction kit according to claim 1, characterized in that: The shape and size of the inner wall of the sealing groove (409) match the shape and size of the outer wall of the sealing ring (410), and the inner wall of the sealing groove (409) fits the outer wall of the sealing ring (410).

6. The antigen-antibody reaction kit according to claim 1, characterized in that: The reaction box body (401) forms a fixed structure with the placement box (501) through a fixing bolt (502), and one end of the fixing bolt (502) is threadedly passed through the placement box (501) and extends into the reaction box body (401) for connection.

7. The antigen-antibody reaction kit according to claim 1, characterized in that: The placement box (501) forms a sliding structure with the identification card (505) through the slot (503), and one end of the identification card (505) extends into the slot (503) for connection.

Citation Information

Patent Citations

  • Antigen-antibody reaction box

    CN216209186U