Liquid path system and chemiluminescence immunoassay analyzer

Abstract

The utility model discloses a liquid path system and a chemiluminescence immunoassay analyzer, the liquid path system comprises: a liquid supplementing module, which comprises a cleaning liquid branch, and the cleaning liquid branch comprises a cleaning liquid buffer barrel; the first cleaning module comprises an input pipeline and a plurality of cleaning branches arranged in parallel, and each cleaning branch comprises an injection pump, an electromagnetic reversing valve communicated with the injection pump and an output branch communicated with the electromagnetic reversing valve; wherein the electromagnetic directional valve is communicated with the cleaning fluid buffer barrel through an input pipeline, so that cleaning fluid in the cleaning fluid buffer barrel enters the injection pump through the electromagnetic directional valve; the electromagnetic reversing valve is communicated with the liquid adding needle through an output branch, so that the cleaning liquid in the injection pump is injected into the reaction tube through the liquid adding needle. A plurality of cleaning branches which are connected in parallel are arranged in a first cleaning module, each cleaning branch is provided with an injection pump and an electromagnetic reversing valve which can be independently controlled, and the electromagnetic reversing valves are subjected to reversing control, so that liquid suction and liquid spitting of the injection pumps are realized, and cleaning liquid in the injection pumps is controllably injected into a reaction tube to clean a conjugate in the reaction tube; therefore, the liquid adding precision of each cleaning branch can be guaranteed.

Description

Technical Field

[0001] The utility model relates to the technical field of medical detection equipment, in particular to a liquid circuit system and a chemiluminescent immunoassay analyzer. Background Art

[0002] The chemiluminescent immunoassay analyzer is a medical testing instrument that performs immunoassay on the human body by testing the patient's serum. It mainly includes: a liquid adding arm, a cleaning plate, a sample library, an incubation plate, a reagent compartment, a test plate, etc. The chemiluminescent immunoassay analyzer can automatically test samples and has the advantages of automation and high efficiency. Figure 1 As shown, when the reaction tubes in the cleaning plate are cleaned, the liquid path devices used are a plunger pump and four two-way solenoid valves. The on-off of the solenoid valve 1-1 is used to control the liquid suction of the plunger pump 1-2, and the on-off of the solenoid valve 1-3 is used to control the plunger pump 1-2 to pump liquid into the reaction tubes in the cleaning plate. When only one of the channels pumps liquid, the liquid addition accuracy into the reaction tubes in the cleaning plate is reliable and easy to control. If two or three channels pump liquid at the same time, the liquid addition accuracy is difficult to control. Utility Model Content

[0003] The utility model aims to provide a liquid path system and a chemiluminescent immunoassay analyzer.

[0004] The first aspect of the utility model provides a liquid circuit system, including: a liquid replenishing module, which includes a cleaning liquid branch, and the cleaning liquid branch includes a cleaning liquid buffer barrel; a first cleaning module, which includes an input pipeline and a plurality of cleaning branches arranged in parallel, each cleaning branch includes an injection pump, an electromagnetic reversing valve connected to the injection pump, and an output branch connected to the electromagnetic reversing valve; wherein the electromagnetic reversing valve is connected to the cleaning liquid buffer barrel through the input pipeline, so that the cleaning liquid in the cleaning liquid buffer barrel enters the injection pump via the electromagnetic reversing valve; the electromagnetic reversing valve is connected to the liquid adding needle through the output branch, so that the cleaning liquid in the injection pump is injected into the reaction tube via the liquid adding needle.

[0005] Furthermore, the liquid circuit system also includes: a cooling module, which includes a cooling branch, and the cooling branch is connected to the shell of the reagent chamber so that coolant is passed into the shell of the reagent chamber for cooling; wherein, the cooling branch includes an electric pump and a radiator connected to the input end of the electric pump, the input end of the shell of the reagent chamber is connected to the output end of the electric pump, and the output end of the shell of the reagent chamber is connected to the radiator, so that the coolant flows through the electric pump, the shell of the reagent chamber and the radiator in sequence and circulates.

[0006] Furthermore, the injection pump is configured as a triplet injection pump; and the electromagnetic reversing valve is configured as a two-position three-way electromagnetic valve.

[0007] Furthermore, the liquid circuit system also includes: a waste liquid module, which includes a first peristaltic pump and a waste liquid buffer barrel connected to the output end of the first peristaltic pump, and the input end of the first peristaltic pump is provided with a plurality of first waste liquid branches and second waste liquid branches in parallel; wherein, the first waste liquid branch is connected to the pipetting needle so that the first peristaltic pump extracts the waste liquid generated by the first cleaning module into the waste liquid buffer barrel; the second waste liquid branch is connected to the pipetting needle so that the first peristaltic pump extracts the waste liquid in the reaction tube after the detection is completed.

[0008] Furthermore, the liquid circuit system also includes: an excitation liquid module, which includes an excitation liquid barrel, an excitation liquid reserve barrel, a metering pump group and a third solenoid valve group, the excitation liquid reserve barrel and the excitation liquid barrel are connected to the input end of the third solenoid valve group, and the output end of the third solenoid valve group is connected to the metering pump group, so as to supply the excitation liquid stored in the excitation liquid reserve barrel or the excitation liquid barrel to the metering pump group through the control of the third solenoid valve group.

[0009] Furthermore, the liquid circuit system also includes: a pure water cleaning module, which includes a pure water barrel and at least one second peristaltic pump, the pure water barrel is connected to the second peristaltic pump, and the output end of the second peristaltic pump is connected to the metering pump group, so that the pure water stored in the pure water barrel is input into the metering pump group through the second peristaltic pump to clean the internal cavity of the metering pump.

[0010] Furthermore, the metering pump group is connected to the waste liquid buffer barrel so that the waste water after cleaning the internal cavity of the metering pump enters the waste liquid buffer barrel; a filter is provided between the pure water barrel and the second peristaltic pump.

[0011] Furthermore, the liquid circuit system also includes: a second cleaning module, which includes: a first diaphragm pump and a first solenoid valve group connected in sequence, and an external cleaning branch and an internal cleaning branch respectively connected to the first solenoid valve group; the external cleaning branch includes: a first liquid supply pipeline connected to the first solenoid valve group and the sample cleaning tank or the reagent cleaning tank; the internal cleaning branch includes: at least one first plunger pump, and a second liquid supply pipeline connected to the first plunger pump and the inside of the sample needle or the reagent needle; the fluid replenishment module also includes a system liquid branch, and the system liquid branch includes a system liquid buffer barrel; the system liquid buffer barrel is connected to the external cleaning branch so that the system liquid is injected into the sample cleaning tank or the reagent cleaning tank, thereby cleaning the outer wall of the sample needle or the reagent needle; the system liquid buffer barrel is connected to the internal cleaning branch so that the system liquid is injected into the sample needle or the reagent needle, thereby cleaning the inner wall of the sample needle or the reagent needle.

[0012] The second aspect of the utility model provides a chemiluminescent immunoassay analyzer, comprising a cleaning unit, a detection unit, a sample needle robot, a reagent needle robot, and the liquid circuit system; wherein the second cleaning module in the liquid circuit system provides system liquid to the sample needle robot and the reagent needle robot respectively, the first cleaning module in the liquid circuit system provides cleaning liquid to the cleaning unit respectively, and the excitation liquid module provides excitation liquid to the detection unit respectively; the waste liquid generated by the cleaning unit, the detection unit, the sample needle robot and the reagent needle robot is discharged through the waste liquid module.

[0013] The above technical solution of the utility model has the following beneficial technical effects:

[0014] 1. By setting a plurality of parallel cleaning branches in the first cleaning module, each cleaning branch is provided with a separately controllable injection pump and an electromagnetic reversing valve, and the electromagnetic reversing valve is reversingly controlled to realize the suction and discharge of the injection pump. When the electromagnetic reversing valve is in a normally closed state, the injection pump starts to suck liquid, and the cleaning liquid in the cleaning liquid buffer barrel enters the cavity of the injection pump through the electromagnetic reversing valve; when a single path is pumping liquid, the electromagnetic reversing valve of the path is switched to a normally open state, and the injection pump performs controllable liquid pumping, and the cleaning liquid is injected into the reaction tube through the liquid filling needle to clean the binding substances in the reaction tube and remove interfering substances. It can be seen that the liquid filling accuracy on the cleaning branch is reliable; if two or three paths are pumping liquid at the same time, the switching of different electromagnetic reversing valves on each cleaning branch is controlled to pump liquid, so that the liquid filling accuracy on each cleaning branch can be guaranteed.

[0015] 2. Cooling water is introduced into the shell of the reagent compartment for circulating cooling, which can improve the heat dissipation effect of the shell of the reagent compartment and maintain 2-8°C in the reagent compartment to achieve effective and reliable refrigeration of the loaded reagent kit, further reducing the instrument failure rate. BRIEF DESCRIPTION OF THE DRAWINGS

[0016] Figure 1 It is a schematic diagram of the structure of the liquid path device in the cleaning process in the prior art;

[0017] Figure 2 is a schematic diagram of a fluid circuit system according to a first embodiment of the utility model;

[0018] Figure 3 is a schematic diagram of a first cleaning module in a liquid circuit system according to a second embodiment of the present utility model;

[0019] Figure 4 is a schematic diagram of a cooling module in a liquid circuit system according to a third embodiment of the present utility model;

[0020] Figure 5It is a schematic structural diagram of a chemiluminescent immunoassay analyzer according to the fourth embodiment of the present utility model. DETAILED DESCRIPTION

[0021] In order to make the purpose, technical solution and advantages of the utility model clearer, the utility model is further described in detail below in combination with specific implementation methods and with reference to the accompanying drawings. It should be understood that these descriptions are only exemplary and are not intended to limit the scope of the utility model. In addition, in the following description, the description of well-known structures and technologies is omitted to avoid unnecessary confusion of the concept of the utility model.

[0022] The first aspect of the utility model provides a fluid circuit system, such as Figure 2-Figure 4 As shown, it includes: a replenishing module, which includes a cleaning liquid branch 11, and the cleaning liquid branch 11 includes a cleaning liquid buffer barrel Y5; a first cleaning module 12, which includes an input pipeline 121 and a plurality of cleaning branches arranged in parallel, each cleaning branch includes an injection pump SR3, an electromagnetic reversing valve SV3 connected to the injection pump SR3, and an output branch 122 connected to the electromagnetic reversing valve; wherein the electromagnetic reversing valve SV3 is connected to the cleaning liquid buffer barrel Y5 through the input pipeline 121, so that the cleaning liquid in the cleaning liquid buffer barrel Y5 enters the injection pump SR3 via the electromagnetic reversing valve SV3; the electromagnetic reversing valve SV3 is connected to the liquid adding needle 1B through the output branch 122, so that the cleaning liquid in the injection pump SR3 is injected into the reaction tube through the liquid adding needle 1B.

[0023] Specifically, the cleaning liquid branch 11 may also include a cleaning liquid storage barrel Y2, and a first electric pump LP6 located between the cleaning liquid storage barrel Y2 and the cleaning liquid buffer barrel Y5, the first electric pump LP6 is used to extract the cleaning liquid in the cleaning liquid storage barrel into the cleaning liquid buffer barrel; the cleaning liquid buffer barrel and the cleaning liquid storage barrel are both provided with a liquid level sensor, the liquid level sensor is used to monitor the liquid level in the barrel. The provision of the cleaning liquid buffer barrel can ensure timely replenishment of the cleaning liquid, further improve the working efficiency of the analyzer, so that the analyzer does not need to be shut down and can work continuously. A filter FV2 may be provided on the input pipeline 121, and the filter FV2 is used to remove impurities in the cleaning liquid; the input pipeline 121 is divided into a plurality of cleaning branches 11 arranged in parallel by a three-way joint, and the injection pump SR3 may be, for example, an independent single electric pump. When the plurality of cleaning branches 11 arranged in parallel are, for example, three, the injection pump SR3 may be a triplet injection pump, that is, the three pump bodies are driven by the same motor, so that the three pump bodies can suck and pump out liquid separately, which can improve the efficiency under the same working conditions and make the medium transportation faster and more efficient; when the electromagnetic reversing valve SV3 is in the normally closed state, the injection pump SR3 starts to suck liquid, and the cleaning liquid in the cleaning liquid buffer barrel Y5 is sucked by the electromagnetic reversing valve SV3 enters the cavity of the syringe pump SR3; when a single route is used to pump liquid, the electromagnetic reversing valve SV3 of that route is switched to the normally open state, and the syringe pump SR3 pumps liquid. The electromagnetic reversing valve SV3 is connected to the liquid adding needle 1B through the output branch 122, so that the cleaning liquid in the syringe pump SR3 is injected into the reaction tube through the liquid adding needle 1B. The cleaning liquid is used to clean the conjugate in the reaction tube and remove interfering substances; since the volume in each pump body is certain, the cleaning liquid injected into the reaction tube can be controlled, which shows that the liquid adding accuracy is reliable. If two or three routes are pumping liquid at the same time, the switching of different electromagnetic reversing valves on each cleaning branch is controlled to pump liquid, so the liquid adding accuracy on each cleaning branch can be guaranteed. Preferably, the electromagnetic reversing valve SV3 can use a two-position three-way electromagnetic valve.

[0024] The reagent compartment of the chemiluminescent immunoassay analyzer is used to load the reagent kit and keep it refrigerated at 2-8°C. If cold air is introduced into the shell of the reagent compartment for cooling, the heat dissipation effect is poor, which may easily lead to instrument failure. In response to this technical problem, the applicant of this application has also made the following design:

[0025] In some embodiments, the liquid circuit system also includes: a cooling module 20, which includes a cooling branch, and the cooling branch is connected to the shell 22 of the reagent chamber so that coolant is passed into the shell 22 of the reagent chamber for cooling; wherein, the cooling branch includes an electric pump CP1 and a radiator 21 connected to the input end of the electric pump CP1, the input end of the shell 22 of the reagent chamber is connected to the output end of the electric pump CP1, and the output end of the shell 22 of the reagent chamber is connected to the radiator 21, so that the coolant flows through the electric pump CP1, the shell of the reagent chamber and the radiator 21 in sequence and circulates. Specifically, a drain port may be provided on the shell 22 of the reagent bin, so that waste water in the shell 22 of the reagent bin can be regularly discharged into a trash can, or the shell 22 of the reagent bin can be regularly cleaned; the coolant introduced into the shell 22 of the reagent bin can be, for example, cooling water, and a spaced baffle is provided in the shell 22 of the reagent bin so that the introduced cooling water forms an S-line path, and the output end of the shell 22 of the reagent bin can be set higher than the input end of the shell 22 of the reagent bin so that the shell 22 of the reagent bin is filled with cooling water, which can improve the heat dissipation effect, and the cooling water can take away more heat during the circulation process, and the cooling is more uniform; or, a plurality of Peltier modules may be provided on the shell 22 of the reagent bin, and the Peltier modules Used to cool the shell 22 of the reagent compartment so that the temperature in the reagent compartment is maintained at 2-8°C; multiple Peltier modules can be configured to be connected in series to allow cooling water to pass through, that is, the inlet of the first Peltier module is connected to the output end of the electric pump CP1, the outlet of the first Peltier module is connected to the inlet of the next Peltier module, and the outlet of the last Peltier module is connected to the input end of the radiator 21, so that the introduced cooling water flows through multiple Peltier modules in sequence, and the cooling water exchanges heat with the Peltier modules to take away the heat of the Peltier modules, so as to achieve sustainable cooling of the shell 22 of the reagent compartment by the Peltier modules; alternatively, multiple Peltier modules can be configured to be connected in parallel to allow cooling water to pass through. The electric pump CP1 provides power for the circulation of cooling water. After the cooling water flowing out from the output end of the shell 22 of the reagent chamber undergoes heat exchange with the radiator 21, the cooled cooling water can be transported to the shell 22 of the reagent chamber through the electric pump CP1 for circulation. Therefore, the heat dissipation effect of the shell of the reagent chamber can be improved, and the temperature in the reagent chamber can be maintained at 2-8°C, so as to achieve an effective and reliable refrigeration effect for the loaded reagent kit, thereby reducing the instrument failure rate.

[0026] In some embodiments, the liquid circuit system also includes: a waste liquid module, which includes a first peristaltic pump SR4 and a waste liquid buffer barrel Y6 connected to the output end of the first peristaltic pump SR4, and the input end of the first peristaltic pump SR4 is provided with a plurality of first waste liquid branches 31 and second waste liquid branches 32 in parallel; wherein, the first waste liquid branch 31 is connected to the pipetting needle 1A, so that the first peristaltic pump SR4 extracts the waste liquid generated by the first cleaning module 12 into the waste liquid buffer barrel Y6; the second waste liquid branch 32 is connected to the pipetting needle 5A, so that the first peristaltic pump SR4 extracts the waste liquid in the reaction tube after the detection is completed. Specifically, when the cleaning liquid is injected into the reaction tube through the liquid adding needle 1B, the waste liquid generated after cleaning the conjugate in the reaction tube is drawn to the waste liquid buffer bucket Y6 through the liquid aspiration needle 1A and the first waste liquid branch 31 through the first peristaltic pump SR4; when the sample detection is completed, the waste liquid in the reaction tube is drawn to the waste liquid buffer bucket Y6 through the liquid aspiration needle 5A and the second waste liquid branch 32 through the first peristaltic pump SR4; therefore, by adding the second waste liquid branch 32, the waste liquid in the reaction tube after the detection is completed can be sucked away, thereby achieving the effect of solid-liquid separation, so that there is only the reaction tube in the trash can (the residual liquid in the reaction tube can be ignored), which makes the cleaning of the trash can more convenient, thereby avoiding liquid contamination.

[0027] In some embodiments, the liquid circuit system further includes: an excitation liquid module, which includes an excitation liquid barrel Y8, an excitation liquid standby barrel Y9, a metering pump group and a third solenoid valve group, wherein the excitation liquid standby barrel and the excitation liquid barrel are connected to the input end of the third solenoid valve group, and the output end of the third solenoid valve group is connected to the metering pump group, so as to supply the excitation liquid stored in the excitation liquid standby barrel or the excitation liquid barrel to the metering pump group by controlling the third solenoid valve group. The third solenoid valve group may include, for example, a third solenoid valve SV7 and a fourth solenoid valve SV8, and the metering pump group may include, for example, a metering pump SR5, and when the third solenoid valve SV7 is in a normally open state, the metering pump SR5 extracts the excitation liquid stored in the excitation liquid barrel Y8; when the liquid capacity stored in the excitation liquid barrel Y8 is lower than a preset capacity threshold, the third solenoid valve SV7 is closed, the fourth solenoid valve SV8 is opened, and the metering pump SR5 extracts the excitation liquid in the excitation liquid standby barrel Y9; wherein, both the third solenoid valve SV7 and the fourth solenoid valve SV8 may be two-position two-way solenoid valves.

[0028] The above-mentioned excitation liquid module uses the on-off of the solenoid valve to control the liquid injection of the metering pump. When the metering pump does not work for a long time and the liquid is emptied, due to the pH of the excitation liquid, crystallization is likely to occur in the metering pump and cause the metering pump to get stuck. In response to this technical problem, the applicant of this application has also made the following design:

[0029] In some embodiments, the liquid circuit system further includes: a pure water cleaning module, which includes a pure water bucket Y3 and at least one second peristaltic pump SR7, the pure water bucket Y3 is connected to the second peristaltic pump SR7, and the output end of the second peristaltic pump SR7 is connected to the cleaning port of the metering pump group, so that the pure water stored in the pure water bucket Y3 is input into the cleaning port of the metering pump group through the second peristaltic pump to clean the internal cavity of the metering pump. Specifically, a filter FV3 can be set before the second peristaltic pump SR7, and the second peristaltic pump SR7 is used regularly to extract the pure water stored in the pure water bucket Y3 to flush the internal cavity of the metering pump SR5, which can avoid crystallization and cause the metering pump SR5 to get stuck.

[0030] In some embodiments, the metering pump group is connected to the waste liquid buffer barrel Y6 so that the waste water after cleaning the internal cavity of the metering pump SR5 enters the waste liquid buffer barrel Y6; a filter FV3 is provided between the pure water barrel Y3 and the second peristaltic pump SR7. A liquid level sensor may be provided in the waste liquid buffer barrel Y6 to detect the liquid level of the waste liquid stored in the waste liquid buffer barrel Y6. When the liquid level is higher than a set threshold, the electric pump LP7 is started to extract the waste liquid stored in the waste liquid buffer barrel Y6 into the waste liquid barrel Y7. The waste liquid module may also include a sewer discharge branch, which is used to discharge the waste liquid in the waste liquid buffer barrel Y6.

[0031] In some embodiments, the liquid circuit system also includes: a second cleaning module, which includes: a first diaphragm pump LP2, a first solenoid valve group, and an external cleaning branch 41 and an internal cleaning branch 42 respectively connected to the first solenoid valve group; the external cleaning branch 41 includes: a first liquid supply pipeline connected to the first solenoid valve group and the sample cleaning tank Q1 or the reagent cleaning tank Q2; the internal cleaning branch 42 includes: at least one first plunger pump SR1, and a second liquid supply pipeline connecting the first plunger pump SR1 to the inside of the sample needle 2A or the reagent needle 3A; the fluid replenishment module also includes a system liquid branch, and the system liquid branch includes a system liquid buffer barrel Y4, a system liquid storage barrel Y1 and a pump body LP1. The pump body LP1 is located between the system liquid storage barrel Y1 and the system liquid buffer barrel Y4. The pump body LP1 can be, for example, a diaphragm pump, a plunger pump or a peristaltic pump, etc., which can extract the system liquid in the system liquid storage barrel Y1 into the system liquid buffer barrel Y4; the first solenoid valve group can include, for example, a first solenoid valve SV1 and a second solenoid valve SV2. The first diaphragm pump LP2 is started. When the first solenoid valve SV1 is opened, the first plunger pump SR1 sucks the system liquid in the system liquid buffer barrel Y4, and then the first plunger pump SR1 injects the system liquid into the sample needle 2A or the reagent needle 3A, thereby cleaning the inner wall of the sample needle 2A or the reagent needle 3A; when the second solenoid valve SV2 is opened, the system liquid in the system liquid buffer barrel Y4 is input into the external cleaning branch 41, and is injected into the sample cleaning tank Q1 or the reagent cleaning tank Q2 through the first liquid supply pipeline, thereby cleaning the outer wall of the sample needle 2A or the reagent needle 3A. The waste liquid in the sample cleaning pool Q1 and the reagent cleaning pool Q2 is injected into the waste liquid buffer barrel Y6 through the second diaphragm pump LP3 provided on the respective output pipelines.

[0032] The second aspect of the utility model provides a chemiluminescent immunoassay analyzer, such as Figure 5As shown, it includes a cleaning unit 51, a detection unit 52, a sample needle mechanical arm 53, a reagent needle mechanical arm 54, and the liquid circuit system; wherein, the second cleaning module in the liquid circuit system provides system liquid for the sample needle mechanical arm and the reagent needle mechanical arm, the first cleaning module in the liquid circuit system provides cleaning liquid for the cleaning unit, and the excitation liquid module provides excitation liquid for the detection unit; the waste liquid generated by the cleaning unit, the detection unit, the sample needle mechanical arm and the reagent needle mechanical arm is discharged through the waste liquid module. The chemiluminescent immunoassay analyzer may also include an incubation unit 55 and a tube library 100, the incubation unit 55 is used to provide a constant temperature for the sample and reactant in the reaction tube; the tube library 100 includes a cup tray 101, and the tube library 100 can automatically arrange disordered reaction tubes on the cup tray 101. The reaction tubes on the tube library 100 can be transferred in the incubation unit 55, the cleaning unit 51 and the detection unit 52 in the chemiluminescent immunoassay analyzer to carry samples and reagents. The tube warehouse gripper 56 is arranged between the incubation unit 55 and the tube warehouse 100, and can grab the reaction tube from the tube grabbing position on the cup tray 101 and transport it to the incubation unit 55. The reagent compartment 90 is used to load the reagent kit containing the reagent. The reagent needle robot 54 is arranged between the reagent compartment 90 and the incubation unit 55, and the reagent needle robot 54 is used to transfer the reagent in the reagent compartment 90 to the reaction tube on the reagent position.

[0033] The chemiluminescent immunoassay analyzer provided in the embodiment of the present application can meet the requirements of the cleaning unit 51, the detection unit 52, the sample needle mechanical arm 53, and the reagent needle mechanical arm 54 for cleaning liquid, system liquid, excitation liquid, and waste liquid treatment. In the chemiluminescent immunoassay analyzer provided in the embodiment of the present application, the liquid path systems of each unit module can work simultaneously without interfering with each other, which can also save time to a certain extent and improve the working efficiency of the chemiluminescent immunoassay analyzer.

[0034] It should be understood that the above specific embodiments of the present invention are only used to illustrate or explain the principles of the present invention, and do not constitute a limitation on the present invention. Therefore, any modifications, equivalent substitutions, improvements, etc. made without departing from the spirit and scope of the present invention should be included in the protection scope of the present invention. In addition, the claims attached to the present invention are intended to cover all changes and modifications that fall within the scope and boundaries of the attached claims, or the equivalent forms of such scope and boundaries.

Claims

1. A liquid circuit system, characterized in that: include: A liquid replenishing module, comprising a cleaning liquid branch, wherein the cleaning liquid branch comprises a cleaning liquid buffer tank; The first cleaning module comprises an input pipeline and a plurality of cleaning branches arranged in parallel, each cleaning branch comprises an injection pump, an electromagnetic reversing valve connected to the injection pump and an output branch connected to the electromagnetic reversing valve; wherein, The electromagnetic reversing valve is connected to the cleaning liquid buffer barrel through an input pipeline, so that the cleaning liquid in the cleaning liquid buffer barrel enters the injection pump through the electromagnetic reversing valve; The electromagnetic reversing valve is connected with the liquid adding needle through the output branch, so that the cleaning liquid in the injection pump is injected into the reaction tube through the liquid adding needle.

2. The fluid circuit system according to claim 1, characterized in that: Also includes: A cooling module includes a cooling branch, which is connected to the shell of the reagent compartment so that a coolant is passed into the shell of the reagent compartment for cooling; wherein, The cooling branch includes an electric pump and a radiator connected to the input end of the electric pump, the input end of the reagent compartment shell is connected to the output end of the electric pump, and the output end of the reagent compartment shell is connected to the radiator, so that the coolant flows sequentially and circulates through the electric pump, the reagent compartment shell and the radiator.

3. The fluid circuit system according to claim 1, characterized in that: The syringe pump is set as a triple syringe pump; The electromagnetic reversing valve is set as a two-position three-way electromagnetic valve.

4. The fluid circuit system according to claim 1, characterized in that: Also includes: A waste liquid module, comprising a first peristaltic pump and a waste liquid buffer barrel connected to the output end of the first peristaltic pump, wherein the input end of the first peristaltic pump is provided with a plurality of first waste liquid branches and second waste liquid branches in parallel; wherein, The first waste liquid branch is connected to the liquid suction needle, so that the first peristaltic pump draws the waste liquid generated by the first cleaning module into the waste liquid buffer barrel; The second waste liquid branch is connected to the liquid aspiration needle, so that the first peristaltic pump can extract the waste liquid in the reaction tube after the detection is completed.

5. The fluid circuit system according to claim 4, characterized in that: Also includes: The excitation liquid module includes an excitation liquid barrel, an excitation liquid reserve barrel, a metering pump group and a third solenoid valve group. The excitation liquid reserve barrel and the excitation liquid barrel are connected to the input end of the third solenoid valve group, and the output end of the third solenoid valve group is connected to the metering pump group, so as to supply the excitation liquid stored in the excitation liquid reserve barrel or the excitation liquid barrel to the metering pump group through the control of the third solenoid valve group.

6. The fluid circuit system according to claim 5, characterized in that: Also includes: A pure water cleaning module comprises a pure water bucket and at least one second peristaltic pump. The pure water bucket is connected to the second peristaltic pump, and the output end of the second peristaltic pump is connected to the metering pump group, so that the pure water stored in the pure water bucket is input into the metering pump group through the second peristaltic pump to clean the internal cavity of the metering pump.

7. The fluid circuit system according to claim 6, characterized in that: The metering pump group is connected to the waste liquid buffer barrel so that the waste water after cleaning the internal cavity of the metering pump enters the waste liquid buffer barrel; A filter is arranged between the pure water bucket and the second peristaltic pump.

8. The fluid circuit system according to claim 1, characterized in that: Also includes: The second cleaning module comprises: a first diaphragm pump and a first electromagnetic valve group which are connected in sequence, and an external cleaning branch and an internal cleaning branch which are respectively connected to the first electromagnetic valve group; The external cleaning branch includes: a first liquid supply pipeline connected to the first electromagnetic valve group and the sample cleaning tank or the reagent cleaning tank; The internal cleaning branch includes: at least one first plunger pump, and a second liquid supply pipeline connected between the first plunger pump and the inside of the sample needle or the reagent needle; The liquid replenishment module also includes a system liquid branch, and the system liquid branch includes a system liquid buffer tank; The system liquid buffer barrel is connected to the external cleaning branch, so that the system liquid is injected into the sample cleaning pool or the reagent cleaning pool, thereby cleaning the outer wall of the sample needle or the reagent needle; The system liquid buffer barrel is communicated with the internal cleaning branch so that the system liquid is injected into the sample needle or the reagent needle, thereby cleaning the inner wall of the sample needle or the reagent needle.

9. A chemiluminescent immunoassay analyzer, characterized in that: It comprises a cleaning unit, a detection unit, a sample needle mechanical arm, a reagent needle mechanical arm, and a liquid path system as claimed in any one of claims 1 to 8; wherein, The second cleaning module in the liquid circuit system provides system liquid to the sample needle robot and the reagent needle robot respectively, the first cleaning module in the liquid circuit system provides cleaning liquid to the cleaning unit respectively, and the excitation liquid module provides excitation liquid to the detection unit respectively; the waste liquid generated by the cleaning unit, the detection unit, the sample needle robot and the reagent needle robot is discharged through the waste liquid module.

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