Water bath device capable of oscillating

By designing a oscillable water bath device, using the combined structure of sliding plate, limiting shaft and mounting plate, the problem of difficulty in fixing and oscillating 96-well incubation plates during water bath incubation is solved, and the authenticity and repeatability of experimental data are achieved.

CN222777954UActive Publication Date: 2025-04-22GUIZHOU BEIKE FACTORR BIOTECH CO LTD
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Patent Information

Application Number
CN202420612598.9
Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
Filing Date
2024-03-27
Publication Date
2025-04-22
Estimated Expiration
2034-03-27

AI Technical Summary

Technical Problem

During the water bath incubation process, the 96-well incubation plate is difficult to fix and oscillates with the water bath device, resulting in the authenticity and repeatability of the data.

Method used

A vibrating water bath device is designed. By setting a sliding plate on the top of the housing and using an electric push rod to drive the sliding plate to reciprocate, the limiting shaft and the mounting plate are coupled with the incubation plate, and the incubation plate is fixed with a spring clip to ensure that it oscillates with the water bath device.

Benefits of technology

The stable fixation and oscillation of the 96-well incubation plate was achieved, which improved the authenticity and repeatability of the experimental data, and the structure was simple and the operation was fast.

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Abstract

The utility model relates to the technical field of biological medicine, and particularly discloses an oscillatory water bath device which comprises a shell, the shell is in a box shape with an upward opening, the upper ends of the two opposite side walls of the shell are slidably connected with oscillation units, each oscillation unit comprises a sliding plate and a limiting shaft, and the side wall of each sliding plate is connected with the output end of an electric push rod; the sliding plate can slide back and forth along the top wall of the shell through the electric push rod, the limiting shafts are vertically connected to the bottom of the sliding plate, a horizontal mounting plate is detachably connected between the limiting shafts, a first clamping plate capable of bearing an incubation plate is arranged on the mounting plate, and spring clamps are arranged on the opposite side walls of the first clamping plate respectively. And the two side walls of the incubation plate can abut against each other through the spring clips. According to the scheme, the problem that the incubation plate is difficult to fix and oscillate along with the water bath device when the water bath is carried out on the porous incubation plate at present can be solved.
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Description

Technical Field

[0001] The utility model relates to the technical field of biomedicine, in particular to an oscillating water bath device. Background Art

[0002] Water bath heating refers to transferring heat to the container that needs to be heated by heating water. The conditions are mild and controllable. It is a commonly used treatment method in the field of chemistry to promote the dissolution of substances or chemical reactions. At present, in the process of biomedical research and development, water bath incubation is a more realistic reflection of human metabolism in the drug evaluation process. At the same time, compared with other temperature control equipment, water baths have great advantages. The temperature is less affected by the system, the temperature accuracy is higher, and experiments can be carried out in an open environment. The operability is strong during the experiment.

[0003] During the drug metabolism simulation process, the incubation system needs to be continuously oscillated, and the incubation container needs to be fixed to ensure that the container is always below the water level. At the same time, the oscillation frequency and the instrument setting value need to maintain a high degree of consistency to ensure the authenticity and repeatability of the data; 96-well incubation plates are increasingly used in incubation experiments. In vitro drug evaluation experiments generally require multi-step operations, which are more operable under open water bath conditions. However, 96-well plates are generally made of polypropylene, which has a low density and is easy to float on the water surface. It cannot truly oscillate with the oscillation plate of the oscillating water bath, so effective measures need to be taken to fix the 96-well incubation plate on the oscillation plate. Utility Model Content

[0004] The utility model provides an oscillating water bath device to solve the problem that it is difficult to fix the incubation plate and make the incubation plate oscillate with the water bath device when the multi-hole incubation plate is water bathed.

[0005] To solve the above problems, the technical solution adopted by the utility model is as follows: an oscillating water bath device, comprising a shell, the shell is a box-shaped shell with an opening facing upward, and the upper ends of the two opposite side walls of the shell are slidably connected with an oscillation unit, the oscillation unit comprises a sliding plate and a limiting shaft, the side walls of the sliding plate are connected with the output end of an electric push rod, and the sliding plate can be reciprocated along the top wall of the shell by the electric push rod, the limiting shafts are respectively vertically connected to the bottom of the sliding plate, and a horizontal mounting plate is detachably connected between the limiting shafts, and a first clamping plate that can carry an incubation plate is provided on the mounting plate, and spring clips are respectively provided on the opposite side walls of the first clamping plate, and the two side walls of the incubation plate can be pressed against each other by the spring clips.

[0006] The basic scheme of this scheme is: a sliding plate is set on the top of the shell, and the sliding plate is driven by an electric push rod to slide back and forth in the horizontal direction. The limit shaft is connected to the sliding plate and reciprocates with the sliding plate. A mounting plate is horizontally set on the limit shaft, and the limit shaft drives the mounting plate to move together. The incubation plate is clamped on the mounting plate, and the incubation plate oscillates together with the mounting plate.

[0007] The beneficial effects of this solution are as follows: when the existing device puts the multi-porous incubation plate in a water bath, it is difficult to fix the incubation plate and make the incubation plate oscillate with the water bath device. This solution is designed to clamp the first clamping plate of the incubation plate, fix the incubation plate on the first clamping plate with a spring clip, and limit the position of the first clamping plate inside the shell with a limiting shaft, so that the incubation plate can oscillate back and forth following the movement of the limiting shaft while being in a water bath in the shell. At the same time, the structure is simple and the operation is quick.

[0008] Furthermore, the limiting shaft includes a plurality of first connecting shafts connected in sequence, the vertices of the mounting plate are respectively vertically penetrated with first through holes, the inner diameter of the first through holes is the same as the maximum outer diameter of the first connecting shaft, and the first connecting shaft is detachably connected with a support ring, the inner diameter of the support ring is smaller than the inner diameter of the first through hole. The height of the mounting plate in the housing is limited by the cooperation of the first connecting shaft and the support ring, so that multiple incubation plates can be simultaneously subjected to water bath oscillation.

[0009] Furthermore, the upper end of the first connecting shaft is provided with a threaded portion, and the lower end of the first connecting shaft is provided with a threaded groove, and the threaded portion matches the threaded groove. The first connecting shaft connected by threads is used to form a limit shaft, and the length of the limit shaft can be adjusted automatically.

[0010] Furthermore, a magnet is embedded on the inner wall of the support ring, a magnetic column is embedded in the threaded portion, and the polarities of the magnet and the magnetic column at opposite ends are different, thereby improving the installation stability of the support ring on the limiting column.

[0011] Furthermore, the upper part of the incubation plate is in the shape of a rectangular plate, and holes are formed on the surface of the incubation plate, and the lower end of the hole is in the shape of a tapered test tube stretched downward, and the first clamping plate is provided with vertical second through holes at the tapered test tube ends of the incubation plate, and the mounting plate is also provided with third through holes at the locations corresponding to the second through holes, so as to ensure that the bottom of the incubation plate can contact with the water flow.

[0012] Furthermore, a slide groove is provided on the upper length of the opposite end of the sliding plate and the top wall of the housing, and a convex strip is provided on the top wall of the housing corresponding to the slide groove, and the sliding plate slides along the top wall of the housing through the cooperation between the slide groove and the convex strip. The sliding plate is installed using the slide groove and convex strip structure. BRIEF DESCRIPTION OF THE DRAWINGS

[0013] Figure 1 A schematic diagram of an embodiment of the utility model;

[0014] Figure 2 for Figure 1 Enlarged schematic diagram of part A. DETAILED DESCRIPTION

[0015] The following is further described in detail through specific implementation methods:

[0016] The figure marks in the drawings of the specification include: shell 1, sliding plate 2, slide groove 3, convex strip 4, electric push rod 5, limit shaft 6, first connecting shaft 7, threaded portion 8, mounting plate 9, first through hole 91, first clamping plate 10, second through hole 11, spring clip 12, support ring 13, incubation plate 14.

[0017] The embodiment is basically as shown in the attached Figure 1 To Attachment Figure 2 As shown:

[0018] An oscillating water bath device includes a shell 1, which is in the shape of a box with an opening facing upward. Heating wires are installed at intervals on the inner wall of the shell 1. The water received inside the shell 1 can be heated by the heating wires. The heating wires are electrically connected to an external controller, and the controller is used to control the opening and closing of the heating wires. An oscillating unit is slidably connected to the upper ends of the two opposite side walls of the shell 1. The oscillating unit includes a sliding plate 2 and a limit shaft 6. The sliding plate 2 is slidably connected to the top wall of the shell 1 in a "7" shape. A slide groove 3 is arranged along the length of the upper ends of the opposite ends of the sliding plate 2 and the top wall of the shell 1. A convex strip 4 is arranged on the top wall of the shell 1 corresponding to the slide groove 3. An electric push rod 5 is also fixedly installed on the top wall of the shell 1. The electric push rod 5 is axially horizontal. The output end of the electric push rod 5 is connected to the side wall of the sliding plate 2. The reciprocating extension and retraction of the electric push rod 5 can drive the entire sliding plate 2 to slide back and forth. The electric push rod 5 is also electrically connected to the controller, and the controller is also used to control the opening and closing of the electric push rod 5.

[0019] A vertical limiting shaft 6 is connected to one side of the sliding plate 2 close to the inside of the housing 1. There are two limiting shafts 6 on a single sliding plate 2. The limiting shafts 6 are symmetrically arranged along the length center axis of the sliding plate 2. The limiting shaft 6 includes a plurality of first connecting shafts 7 connected in sequence. The upper end of the first connecting shaft 7 is a threaded portion 8. The lower end of the first connecting shaft 7 is an internal thread groove opening downward. The threaded portion 8 of one first connecting shaft 7 is threadedly connected to the internal thread groove of another first connecting shaft 7. This is repeated to form a limiting shaft 6 with a custom length. A threaded hole is opened on the bottom wall of the sliding plate 2, and the installed limiting shaft 6 can be threadedly connected to the sliding plate 2 through the threaded hole.

[0020] In this embodiment, a total of four limiting shafts 6 are installed on two opposite side walls of the shell 1, thereby forming four vertices of the frame. The upper ends of the four limiting shafts 6 horizontally pass through the mounting plate 9, and the mounting plate 9 is in the shape of a rectangular plate. The four vertices of the mounting plate 9 are respectively vertically penetrated by first through holes 91. The inner diameter of the first through hole 91 matches the maximum outer diameter of the first connecting shaft 7, so that multiple layers of mounting plates 9 can be arranged along the limiting shaft 6.

[0021] A first clamping plate 10 is fixed on the top surface of the mounting plate 9, and spring clips 12 are rotatably connected to the side walls at both ends of the first clamping plate 10. In this embodiment, the spring clips 12 are common spring clips 12 on paper clips. In a normal state, the torsion spring in the spring clip 12 is in a contracted state, and the torsion spring is opened by pulling the finger. The spring clips 12 on the first clamping plate 10 are arranged oppositely, so that the incubation plate 14 can be clamped from opposite sides to ensure the stability of the incubation plate 14 on the mounting plate 9.

[0022] like Figure 1 As shown, the upper part of the incubation plate 14 is a rectangular plate, and a hole pattern is spaced apart on the surface of the incubation plate 14, and the lower end of the hole pattern is a tapered test tube shape stretched downward. A vertical second through hole 11 is respectively opened on the first card plate 10 corresponding to the tapered test tube end of the incubation plate 14, so as to ensure that the tapered test tube can penetrate the second through hole 11, and at the same time, a third through hole is opened on the mounting plate 9 corresponding to the second through hole 11, so that the water flow in the housing 1 can pass through the second through hole 11 and the third through hole to cover the lower end of the tapered test tube, thereby ensuring the water bath effect.

[0023] A support ring 13 is clamped on the outer wall of the limiting shaft 6 below the first through hole 91 of the mounting plate 9. The support ring 13 is in an incomplete ring shape, and an opening is opened on the side wall of the support ring 13. The inner diameter of the support ring 13 is smaller than the inner diameter of the first through hole 91, so that the support ring 13 can be directly clamped horizontally on the limiting shaft 6, and the lower wall of the support ring 13 can be lifted by the top wall at the step on the first connecting shaft 7. In this embodiment, in order to increase the stability of the support ring 13, a magnetic column is embedded in the threaded portion 8, and a magnet is also embedded on the inner wall of the support ring 13. The magnetic pole of the magnetic column is different from the magnetic pole of the magnet, so that the support ring 13 can be adsorbed on the threaded portion 8.

[0024] The specific implementation process is as follows:

[0025] Thread multiple first connecting shafts 7 in sequence to form four limit columns, take the mounting plate 9 and pass the mounting plate 9 horizontally through the limit columns, clamp the support ring 13 on the four vertices of the mounting plate 9 respectively, so as to ensure that the mounting plate 9 is clamped on the limit columns up and down, and the limit columns are threadedly installed on the sliding plate 2 respectively, and the upper end threaded portion 8 of the limit column is connected to the threaded hole on the bottom wall of the sliding plate 2. After the limit column is installed, the mounting plate 9 is limited to a fixed height in the shell 1.

[0026] Pull the spring clip 12 on the mounting plate 9, align the conical test tube on the incubation plate 14 with the second through hole 11 and place it flat on the first clamping plate 10, loosen the spring clips 12 on both sides, and the spring clips 12 rotate towards each other to clamp the incubation plate 14, add water into the shell 1, start the heating wire, and after the water temperature is heated to a preset temperature, start the electric push rod 5, which drives the sliding plate 2 to slide back and forth in the horizontal direction, thereby forming oscillation, and the entire incubation plate 14 is subjected to oscillation to perform the incubation process.

[0027] The above is only an embodiment of the utility model, and the common knowledge such as the known specific structure and characteristics in the scheme is not described in detail here. It should be pointed out that for those skilled in the art, several deformations and improvements can be made without departing from the structure of the utility model, which should also be regarded as the protection scope of the utility model, and these will not affect the effect of the implementation of the utility model and the practicality of the patent. The scope of protection required by this application shall be based on the content of its claims, and the specific implementation methods and other records in the specification can be used to interpret the content of the claims.

Claims

1. An oscillating water bath device, characterized in that: It includes a shell, which is a box-shaped shell with an opening upward. The upper ends of the two opposite side walls of the shell are slidably connected with an oscillation unit. The oscillation unit includes a sliding plate and a limiting shaft. The side walls of the sliding plate are connected with the output end of an electric push rod. The sliding plate can be reciprocated along the top wall of the shell by the electric push rod. The limiting shafts are vertically connected to the bottom of the sliding plate respectively. A horizontal mounting plate is detachably connected between the limiting shafts. A first clamping plate that can carry an incubation plate is provided on the mounting plate. Spring clips are respectively provided on the opposite side walls of the first clamping plate. The two side walls of the incubation plate can be pressed against each other by the spring clips.

2. An oscillating water bath device according to claim 1, characterized in that: The limiting shaft includes a plurality of first connecting shafts connected in sequence, and first through holes are vertically penetrated through the vertices of the mounting plate respectively. The inner diameter of the first through hole is the same as the maximum outer diameter of the first connecting shaft. A support ring is detachably connected to the first connecting shaft, and the inner diameter of the support ring is smaller than the inner diameter of the first through hole.

3. An oscillating water bath device according to claim 2, characterized in that: The upper end of the first connecting shaft is provided with a threaded portion, and the lower end of the first connecting shaft is provided with a threaded groove inside, and the threaded portion matches the threaded groove.

4. An oscillating water bath device according to claim 3, characterized in that: A magnet is embedded on the inner wall of the support ring, a magnetic column is embedded inside the threaded portion, and the polarities of the magnet and the magnetic column at opposite ends are different.

5. An oscillating water bath device according to claim 4, characterized in that: The upper part of the incubation plate is a rectangular plate, and holes are spaced apart on the surface of the incubation plate. The lower end of the hole is a downwardly stretched conical test tube shape. The first card plate corresponds to the conical test tube end of the incubation plate and has vertical second through holes. The mounting plate also has a third through hole corresponding to the second through hole.

6. An oscillating water bath device according to claim 5, characterized in that: A sliding groove is arranged along the length of the upper end opposite to the top wall of the housing, and a convex strip is arranged at the top wall of the housing corresponding to the sliding groove, and the sliding groove cooperates with the convex strip to enable the sliding plate to slide along the top wall of the housing.